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Fibromyalgia in children

Marina de Tommaso, Vittorio Sciruicchio, Marianna Delussi, Eleonora Vecchio, Marvita Goffredo, Michele Simeone, Maria Grazia Foschino Barbaro
BACKGROUND: Central sensitization is an important epiphenomenon of the adult migraine, clinically expressed by allodynia, pericranial tenderness and comorbidity for fibromyalgia in a relevant number of patients. This study aimed to evaluate the frequency and the clinical characteristics of allodynia, pericranial tenderness, and comorbidity for Juvenile Fibromialgia (JFM) in a cohort of migraine children selected in a tertiary headache center. METHODS: This was an observational cross-sectional study on 8-15 years old migraine patients...
December 2017: Journal of Headache and Pain
N Draheim, F Ebinger, E Schnöbel-Müller, B Wolf, W Häuser
BACKGROUND: The regular update of the guidelines on fibromyalgia syndrome, AWMF number 145/004, was scheduled for April 2017. METHODS: The guidelines were developed by 13 scientific societies and 2 patient self-help organizations coordinated by the German Pain Society. Working groups (n = 8) with a total of 42 members were formed balanced with respect to gender, medical expertise, position in the medical or scientific hierarchy and potential conflicts of interest...
May 10, 2017: Der Schmerz
Natoshia R Cunningham, Susmita Kashikar-Zuck, Constance Mara, Kenneth R Goldschneider, Dennis A Revicki, Carlton Dampier, David D Sherry, Lori Crosby, Adam Carle, Karon F Cook, Esi M Morgan
Pain behaviors are important indicators of functioning in chronic pain; however, no self-reported pain behavior instrument has been developed for pediatric populations. The purpose of this study was to create a brief pediatric measure of patient-reported pain behaviors as part of the Patient-Reported Outcome Measurement Information System (PROMIS). A pool of 47 candidate items for this measure had been previously developed through qualitative research. In this study, youth with chronic pain associated with juvenile fibromyalgia, juvenile idiopathic arthritis, or sickle cell disease (ages 8-18 years) from 3 pediatric centers completed all 47 candidate items for development of the pain behavior item bank along with established measures of pain interference, depressive symptoms, fatigue, average pain intensity, and pain catastrophizing...
July 2017: Pain
Terri Voepel-Lewis, Michelle S Caird, Alan R Tait, Shobha Malviya, Frances A Farley, Ying Li, Matthew D Abbott, Tara van Veen, Afton L Hassett, Daniel J Clauw
BACKGROUND: Preoperative pain predicts persistent pain after spine fusion, yet little is understood about the nature of that pain, related symptoms, and how these symptoms relate to postoperative pain outcomes. This prospective study examined children's baseline pain and symptom profiles and the association between a high symptom profile and postoperative outcomes. METHODS: Seventy children (aged 10-17 years) scheduled for correction of idiopathic scoliosis completed pain and symptom surveys during their preoperative visit (ie, pain intensity [0-10 numeric rating scores], a pediatric version of the 2011 fibromyalgia survey criteria [including pain locations and symptom severity scale], neuropathic pain symptoms [painDETECT], and Patient-Reported Outcome Measurement System measures of fatigue, depression, function, pain interference, and pain catastrophizing)...
May 2017: Anesthesia and Analgesia
Linda E Dean, Lesley Arnold, Leslie Crofford, Robert Bennett, Don Goldenberg, Mary-Ann Fitzcharles, Eduardo S Paiva, Roland Staud, Dan Clauw, Piercarlo Sarzi-Puttini, Gareth T Jones, Abimbola Ayorinde, Elisa Fluß, Marcus Beasley, Gary J Macfarlane
OBJECTIVES: The current study investigated whether associations between pain and the additional symptoms associated with fibromyalgia are different in persons with chronic widespread (CWP) compared to multi-site pain (MSP), with or without joint areas. PATIENTS/METHODS: Six studies were utilized: 1958 British birth cohort, EpiFunD, Kid LBP, MUSICIAN, SHAMA and WHEST (females) studies. MSP was defined as the presence of pain in ≥8/≥10 body sites (adults/children) indicated on 4-view body manikins; conducted firstly to include joints (+joints) and secondly without (-joints)...
February 9, 2017: Arthritis Care & Research
Babatunde Hakeem Olaosebikan, Olufemi Oladipo Adelowo, Barakat Adeola Animashaun, Richard Oluyinka Akintayo
BACKGROUND: Paediatric rheumatology service in Sub-Sahara African is virtually not available as there is a shortage of paediatric rheumatologists and other rheumatology health professionals. We aim to describe the clinical spectrum and the frequencies of paediatric rheumatic diseases (PRDs) in Lagos State University Teaching Hospital (LASUTH), Lagos, Nigeria. METHODS: This is a retrospective review of patients with PRDs seen over a five year period (March 2010 to February 2016) at the rheumatology clinic and children ward of LASUTH...
January 31, 2017: Pediatric Rheumatology Online Journal
Ezra M Cohen, Alessio Morley-Fletcher, Darshan H Mehta, Yvonne C Lee
BACKGROUND: To assess the quality of evidence for the effects of psychosocial therapies on pain and function in children with rheumatic diseases. METHODS: We conducted a literature search of MEDLINE and PsycINFO for randomized clinical trials of psychosocial interventions for pain and disability in children with rheumatic diseases from January 1969 to September 2015. Studies with a sample size less than 10 subjects were excluded. Study quality was assessed using the Jadad score...
January 17, 2017: Pediatric Rheumatology Online Journal
Taylor A Betsch, Ayala Y Gorodzinsky, G Allen Finley, Michael Sangster, Jill Chorney
OBJECTIVES: Diagnostic labels can help patients better understand their symptoms and can influence providers' treatment planning and patient interactions. Recurrent pain is common in childhood; however, there are various diagnostic labels used. The objective of this study was to evaluate the influence of diagnostic labels on pediatric healthcare providers' perceptions of pediatric chronic pain patients. METHODS: Using an online survey, providers were randomly assigned to one of two vignette conditions (differing only in diagnostic label provided) and completed questionnaires about their perceptions of the vignette patient...
December 5, 2016: Clinical Journal of Pain
Gisela Chelimsky, Katja Kovacic, Pippa Simpson, Melodee Nugent, Donald Basel, Julie Banda, Thomas Chelimsky
OBJECTIVE: To determine if children with benign joint hypermobility (BJH) syndrome and chronic functional pain disorders have more autonomic dysfunction. STUDY DESIGN: Retrospective chart review study of pediatric patients seen in the pediatric neurogastroenterology and autonomic clinic who underwent autonomic testing and had either a Beighton score of ≥6 and met Brighton criteria for BJH (with BJH) or a score of ≤2 (no BJH). RESULTS: Twenty-one female subjects (10 without BJH) met inclusion criteria; 64% of BJH had diagnosis confirmed by genetics consultation...
October 2016: Journal of Pediatrics
Jennifer M Allen, Danielle M Graef, Jennifer H Ehrentraut, Brooklee L Tynes, Valerie M Crabtree
BACKGROUND: Sleep disruption is a common comorbidity of pediatric pain. Consequences of pain and disrupted sleep, evidence for the pain-sleep relation, and how aspects of illness, treatment, and pharmacological pain management may contribute to or exacerbate these issues are presented. AIMS: This conceptual review explored the relation between pain and sleep in children diagnosed with chronic medical or developmental conditions. The goal of this review is to expand upon the literature by examining common themes in sleep disturbances associated with painful conditions across multiple pediatric illnesses...
July 15, 2016: CNS Neuroscience & Therapeutics
Susan T Tran, Jessica W Guite, Ashley Pantaleao, Megan Pfeiffer, Gregory D Myer, Soumitri Sil, Staci M Thomas, Tracy V Ting, Sara E Williams, Barbara Edelheit, Sylvia Ounpuu, Jennifer Rodriguez-MacClintic, Lawrence Zemel, William Zempsky, Susmita Kashikar-Zuck
OBJECTIVE: Cognitive-behavioral therapy (CBT) is effective in reducing disability among youth with juvenile fibromyalgia (FM); however, engagement in moderate to vigorous physical activity remains poor, even after CBT. The purpose of this study was to evaluate the feasibility and preliminary outcomes of an innovative program combining CBT with specialized neuromuscular exercise: the Fibromyalgia Integrative Training for Teens (FIT Teens) program. METHODS: Adolescents with juvenile FM (n = 22, all female, ages 12-18 years) from 2 urban children's hospitals participated in the 8-week FIT Teens intervention...
March 2017: Arthritis Care & Research
Martin Offenbächer, Niko Kohls, Lynn Walker, Christiane Hermann, Boris Hügle, Natalie Jäger, Matthias Richter, Johannes-Peter Haas
Our objective was to translate the Functional Disability Inventory (FDI) into German, to evaluate its validity and to assess functional limitation in a large cohort of children and adolescents with juvenile fibromyalgia syndrome (jFMS). We administered several questions (e.g., sociodemographics, school-related issues) and questionnaires to 329 patients and one parent. The questionnaires included, among others, a German version of the FDI, the CHAQ (parent report), KIDSCREEN, tender point score (TPS), Depression Inventory for Children and Adolescents (DIKJ) and others...
October 2016: Rheumatology International
Susmita Kashikar-Zuck, Christopher King, Tracy V Ting, Lesley M Arnold
While a majority of research has focused on adult fibromyalgia (FM), recent evidence has provided insights into the presence and impact of FM in children and adolescents. Commonly referred as juvenile fibromyalgia (JFM), youths, particularly adolescent girls, present with persistent widespread pain and cardinal symptoms observed in adult FM. A majority of youth with JFM continue to experience symptoms into adulthood, which highlights the importance of early recognition and intervention. Some differences are observed between adult and juvenile-onset FM syndrome with regard to comorbidities (e...
April 2016: Current Rheumatology Reports
Sadako Vargas, Jay R Lucker
A quantitative summary of existing research examining the effects of The Listening Program (TLP) on various functions in children is presented. Nine studies were used, looking at TLP intervention effects across studies, within each study and for various outcome measures. The studies looked at TLP intervention on children with autism spectrum disorder, Down syndrome, learning disabilities, auditory processing disorders, attention deficit hyperactivity disorders, Rhett syndrome, dyspraxia, cerebral palsy, fibromyalgia, arthritis and stroke...
June 2016: Occupational Therapy International
Manuel Herrador-Colmenero, Inmaculada C Álvarez-Gallardo, Víctor Segura-Jiménez, Fernando Estévez-López, Alberto Soriano-Maldonado, Pedro J Ruiz-Montero, Pablo Tercedor, María José Girela-Rejón, Manuel Delgado-Fernández, Palma Chillón
OBJECTIVES: The aims of this study were to know whether active commuting behaviour differs between fibromyalgia patients and controls, and to test whether active commuting is associated with socioeconomic factors in this population. METHODS: This cross-sectional study included 459 women with fibromyalgia (52.2 years) and 214 female control participants (51.3 years) from Andalusia (southern Spain). Participants reported patterns of active commuting and socioeconomic factors (civil status, accompaniment at home, living with, educational level, and current occupational and professional status)...
March 2016: Clinical and Experimental Rheumatology
Cara M Hoffart, David D Sherry
No abstract text is available yet for this article.
February 2016: Journal of Pediatrics
Bradford W Landry, Philip R Fischer, Sherilyn W Driscoll, Krista M Koch, Cynthia Harbeck-Weber, Kenneth J Mack, Robert T Wilder, Brent A Bauer, Joline E Brandenburg
Chronic pain in children and adolescents can be difficult for a single provider to manage in a busy clinical setting. Part of this difficulty is that pediatric chronic pain not only impacts the child but also the families of these children. In this review article, we discuss etiology and pathophysiology of chronic pain, along with variables that impact the severity of chronic pain and functional loss. We review diagnosis and management of selected chronic pain conditions in pediatric patients, including headache, low back pain, hypermobility, chronic fatigue, postural orthostatic tachycardia syndrome, abdominal pain, fibromyalgia, and complex regional pain syndrome...
November 2015: PM & R: the Journal of Injury, Function, and Rehabilitation
Stalin Ramprakash, Daniel Fishman
Juvenile fibromyalgia in children with sickle cell disease has not been reported in the literature. We report an adolescent patient with sickle cell whose pain symptoms progressed from having recurrent acute sickle cell pain crisis episodes to a chronic pain syndrome over several years. He was eventually diagnosed with juvenile fibromyalgia based on the clinical history and myofascial tender points and his pain symptoms responded better to multidisciplinary strategies for chronic fibromyalgia pain. Chronic pain in sickle cell disease is an area of poor research, and in addition there is inconsistency in the definition of chronic pain in sickle cell disease...
2015: BMJ Case Reports
Theoharis C Theoharides, Julia M Stewart, Erifili Hatziagelaki, Gerasimos Kolaitis
Brain "fog" is a constellation of symptoms that include reduced cognition, inability to concentrate and multitask, as well as loss of short and long term memory. Brain "fog" characterizes patients with autism spectrum disorders (ASDs), celiac disease, chronic fatigue syndrome, fibromyalgia, mastocytosis, and postural tachycardia syndrome (POTS), as well as "minimal cognitive impairment," an early clinical presentation of Alzheimer's disease (AD), and other neuropsychiatric disorders. Brain "fog" may be due to inflammatory molecules, including adipocytokines and histamine released from mast cells (MCs) further stimulating microglia activation, and causing focal brain inflammation...
2015: Frontiers in Neuroscience
Lesley M Arnold, Lucinda Bateman, Robert H Palmer, Yuhua Lin
BACKGROUND: There are no approved medications for juvenile fibromyalgia (JFM), a disorder that is often under-diagnosed. The effects of milnacipran, a drug approved for the management of fibromyalgia (FM) in adults, was assessed in a clinical trial program for JFM. METHODS: Patients, ages 13-17 years who met the Yunus and Masi criteria for JFM and/or 1990 American College of Rheumatology criteria for FM, were enrolled in a responder-enriched, randomized withdrawal trial...
June 26, 2015: Pediatric Rheumatology Online Journal
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