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JOURNAL ARTICLE
Eman Alazmi, Zahraa Akbar, Mariam Aldarweesh, Khalid Almuzayen, Eelaf Husain, Jehad Alharmi, Fatmah Alhadhoud
OBJECTIVES: COVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2 virus). This virus evolved into several variants, each with different severity. There are surges in the numbers of infected patients, commonly described as "waves". In Kuwait, three waves occurred. Our study describes and compares the clinical presentation and outcomes of critically ill pregnant patients infected with different variants. METHODS: This was a retrospective cohort study in two intensive care units (ICU) dedicated to patients with COVID-19...
April 20, 2024: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
#22
JOURNAL ARTICLE
ZhaoMin Huang, Jiayi Zheng, Mingyang Wang, Shaoting Zeng, Miaoting Huang, Shuyi Peng, Jiajun Li, Jiaming Ji, Quan Chen, Xin Xu, Chao Yang, GuiLin Peng, Hanyu Yang
BACKGROUND: In lung transplantation (LTx) surgery, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can provide mechanical circulatory support to patients with cardiopulmonary failure. However, the use of heparin in the administration of ECMO can increase blood loss during LTx. This study aimed to evaluate the safety of heparin-free V-A ECMO strategies. METHODS: From September 2019 to April 2022, patients who underwent lung transplantation at the First Affiliated Hospital of Guangzhou Medical University were retrospectively reviewed...
April 20, 2024: Journal of Cardiothoracic Surgery
#23
JOURNAL ARTICLE
Sasa Rajsic, Benedikt Treml, Nicole Innerhofer, Christine Eckhardt, Aleksandra Radovanovic Spurnic, Robert Breitkopf
OBJECTIVE: The mismatch between the demand for and supply of organs for transplantation is steadily growing. Various strategies have been incorporated to improve the availability of organs, including organ use from patients receiving extracorporeal membrane oxygenation (ECMO) at the time of death. However, there is no systematic evidence of the outcome of grafts from these donors. DESIGN: Systematic literature review (Scopus and PubMed, up to October 11, 2023). SETTING: All study designs...
March 20, 2024: Journal of Cardiothoracic and Vascular Anesthesia
#24
Zhenhua Du, Yu-Hua Zhang, Liang Sun
No abstract text is available yet for this article.
March 13, 2024: Archivos de Bronconeumología
#25
JOURNAL ARTICLE
Li Wang, Xinyan Pang, Shouluan Ding, Ke Pei, Zijia Li, Jianhong Wan
OBJECTIVE: In this study, we investigated the effect of various oxygen therapy regimens on oxygenation in patients with acute type A aortic dissection (AAD). METHODS: A quasi-randomized controlled trial was conducted, in which patients with AAD hospitalized for surgery from June to September 2021 were assigned to the control group (patients received conventional oxygen therapy after postoperative mechanical ventilation, weaning, and extubation) and those who were admitted from October to December 2021 were assigned to the observation group [patients underwent optimally adjusted therapy based on the treatment of the control group, which mainly included prioritized elevation of positive end-expiratory pressure (PEEP) and restricted use of the fraction of inspired oxygen (FiO2 )]...
April 30, 2024: Heliyon
#26
Jose Alejandro Posso-Nuñez, Astrid Carolina Álvarez-Ortega, Diego Fernando Bautista-Rincón, Carlos Alejandro García-González, Indira Fabiana Cujiño-Álvarez, Álvaro Ignacio Sánchez-Ortiz, Mauricio Velásquez-Galvis
A 47-year-old male patient was referred to a level 1 trauma center with refractory acute respiratory distress syndrome, bilateral lung contusions, and flail chest after initial management for injuries sustained 5 days prior from an 8-m fall from a tower crane. Surgical stabilization of the rib fractures was achieved under extracorporeal membrane oxygenation support, with successful decannulation 4 days after surgery. The patient was discharged after 42 days and following multidisciplinary interventions...
June 2024: Trauma Case Reports
#27
JOURNAL ARTICLE
Li-Min Zhu, Chun-Xiang Li, Xiao-Lei Gong, Zhuo-Ming Xu, Jin-Long Liu, Hai-Bo Zhang
BACKGROUND: Plastic bronchitis (PB) can occur in patients who have undergone congenital heart surgery (CHS). This study aimed to investigate the clinical features of PB in children after CHS. METHODS: We conducted a retrospective cohort study using the electronic medical record system. The study population consisted of children diagnosed with PB after bronchoscopy in the cardiac intensive care unit after CHS from May 2016 to October 2021. RESULTS: A total of 68 children after CHS were finally included in the study (32 in the airway abnormalities group and 36 in the right ventricular dysfunction group)...
April 19, 2024: Italian Journal of Pediatrics
#28
JOURNAL ARTICLE
Clare E Ferguson, Kate Hayes, Oana A Tatucu-Babet, Kate J Lambell, Eldho Paul, Carol L Hodgson, Emma J Ridley
BACKGROUND: Adverse changes in muscle health (size and quality) are common in patients receiving extracorporeal membrane oxygenation (ECMO). Nutrition delivery may attenuate such changes, yet the relationship with muscle health remains poorly understood. This study explored the association between energy and protein delivery and changes in muscle health measured using ultrasound from baseline to day 10 and 20 in patients receiving ECMO. METHODS: A secondary analysis of data from a prospective study quantifying changes in muscle health using ultrasound in adults receiving ECMO was completed...
April 17, 2024: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
#29
JOURNAL ARTICLE
W F Shang, D C Chen
Prone positioning ventilation (PPV) is considered one of the essential therapeutic approaches in the management of acute respiratory distress syndrome (ARDS). Several randomized controlled clinical trials have demonstrated the efficacy of PPV in the treatment of patients with ARDS. However, it is not clear whether PPV treatment can reduce mortality in patients with veno-venous extracorporeal membrane oxygenation (VV-ECMO)-supported ARDS and corona virus disease 2019 (COVID-19)-associated ARDS. This review aims to discuss the known and unknown aspects of the mechanism of PPV for ARDS, the clinical efficacy of PPV for ARDS, VV-ECMO-supported ARDS, and COVID-19-related ARDS...
April 16, 2024: Zhonghua Yi Xue za Zhi [Chinese medical journal]
#30
JOURNAL ARTICLE
María V Fraga, Holly L Hedrick, Natalie E Rintoul, Yan Wang, Devon Ash, Sabrina J Flohr, Leny Mathew, Tom Reynolds, Jenny L Engelman, Catherine M Avitabile
OBJECTIVES: To describe the scope of left ventricular (LV) dysfunction and left heart hypoplasia (LHH) in infants with congenital diaphragmatic hernia (CDH), to determine associations with CDH severity, and to evaluate the odds of extracorporeal membrane oxygenation (ECMO) and death with categories of left heart disease. STUDY DESIGN: Demographic and clinical variables were collected from a single-center, retrospective cohort of CDH patients from January 2017 through May 2022...
April 16, 2024: Journal of Pediatrics
#31
JOURNAL ARTICLE
Carlotta Cacciatore, Mathilde Baudet, Estelle Jean, Simona Presente, Marylou Para, Romain Sonneville, Dimitri Arangalage, Nassim Ait Abdallah, Flore Sicre de Fontbrune, Pedro Henrique Prata, Benjamin Crichi, Baptiste Hervier, Nathalie Parquet, Gilles Soulat, Elie Mousseaux, Richard K Burt, Dominique Farge
Systemic sclerosis (SSc) is a rare autoimmune disease (AD), characterised by early diffuse vasculopathy, activation of the immune response and progressive skin and internal organ fibrosis. In severe progressive diffuse SSc (dSSc), autologous hematopoietic stem cell transplantation (aHSCT) improves survival, despite its own risk of complications and transplant related mortality (TRM). We present herein the case of a dSSc patient undergoing aHSCT with low dose cyclophosphamide conditioning and sudden acute myopericarditis and cardiogenic shock, four weeks after a second mRNA SARS-CoV-2 vaccine (Pfizer) injection...
April 9, 2024: Current Research in Translational Medicine
#32
JOURNAL ARTICLE
Laura D Zambrano, Margaret M Newhams, Regina M Simeone, Amanda B Payne, Michael Wu, Amber O Orzel-Lockwood, Natasha B Halasa, Jemima M Calixte, Pia S Pannaraj, Kanokporn Mongkolrattanothai, Julie A Boom, Leila C Sahni, Satoshi Kamidani, Kathleen Chiotos, Melissa A Cameron, Aline B Maddux, Katherine Irby, Jennifer E Schuster, Elizabeth H Mack, Austin Biggs, Bria M Coates, Kelly N Michelson, Katherine E Bline, Ryan A Nofziger, Hillary Crandall, Charlotte V Hobbs, Shira J Gertz, Sabrina M Heidemann, Tamara T Bradford, Tracie C Walker, Stephanie P Schwartz, Mary Allen Staat, Samina S Bhumbra, Janet R Hume, Michele Kong, Melissa S Stockwell, Thomas J Connors, Melissa L Cullimore, Heidi R Flori, Emily R Levy, Natalie Z Cvijanovich, Matt S Zinter, Mia Maamari, Cindy Bowens, Danielle M Zerr, Judith A Guzman-Cottrill, Ivan Gonzalez, Angela P Campbell, Adrienne G Randolph
Pediatric COVID-19 vaccination is effective in preventing COVID-19-related hospitalization, but duration of protection of the original monovalent vaccine during SARS-CoV-2 Omicron predominance merits evaluation, particularly given low coverage with updated COVID-19 vaccines. During December 19, 2021-October 29, 2023, the Overcoming COVID-19 Network evaluated vaccine effectiveness (VE) of ≥2 original monovalent COVID-19 mRNA vaccine doses against COVID-19-related hospitalization and critical illness among U...
April 18, 2024: MMWR. Morbidity and Mortality Weekly Report
#33
JOURNAL ARTICLE
Dariusz Zieliński, Szymon Darocha, Arkadiusz Pietrasik, Michał Machowski, Krzysztof Wróbel, Marcin Kurzyna, Piotr Pruszczyk, Adam Torbicki, Andrzej Biederman
BACKGROUND: This study aimed to assess the prevalence of chronic thromboembolic lesions in the pulmonary arteries among patients undergoing pulmonary embolectomy for acute pulmonary embolism and their impact on treatment outcomes. METHODS: We conducted a retrospective, single-center analysis of consecutive patients undergoing emergency pulmonary embolectomy for acute pulmonary embolism between 2013 and August 2021. According to European Society of Cardiology guidelines, the diagnosis was based on clinical presentation, imaging studies and laboratory tests...
April 18, 2024: Journal of Cardiovascular Surgery
#34
JOURNAL ARTICLE
Jeffrey Balian, Saad Mallick, Nguyen Le, Giselle Porter, Amulya Vadlakonda, Konmal Ali, Elsa Kronen, Peyman Benharash
BACKGROUND: Extracorporeal membrane oxygenation (ECMO) has emerged as a life-sustaining measure for individuals with end-stage cardiopulmonary derangements. An estimated one-third of patients must be transferred to a specialized center to receive this intervention. Therefore, the present study sought to characterize the impact of interhospital transfer (IHT) status on outcomes following ECMO. METHODS: The 2016-2020 National Inpatient Sample was queried to identify all adult (≥18 years) hospitalizations for ECMO...
April 18, 2024: American Surgeon
#35
JOURNAL ARTICLE
Bhoumesh Patel, Ahmed S Said, Angelo Justus, Darryl Abrams, Tái Pham, Marta Velia Antonini, Elizabeth Moore, Kiran Shekar, Bishoy Zakhary
BACKGROUND: The use of extracorporeal membrane oxygenation (ECMO) has grown rapidly over the past decades because of evolving indications, advances in circuit technology, and encouraging results from modern trials. Because ECMO is a complex and highly invasive therapy that requires a multidisciplinary team, optimal education, training, and credentialing remain a challenge. OBJECTIVE: The primary objectives of this study were to investigate the prevalence and application of ECMO education and ECMO practitioner credentialing at ECMO centers globally...
March 2024: ATS scholar
#36
REVIEW
Smitesh Padte, Vikramaditya Samala Venkata, Priyal Mehta, Sawsan Tawfeeq, Rahul Kashyap, Salim Surani
Critical care medicine in the 21st century has witnessed remarkable advancements that have significantly improved patient outcomes in intensive care units (ICUs). This abstract provides a concise summary of the latest developments in critical care, highlighting key areas of innovation. Recent advancements in critical care include Precision Medicine: Tailoring treatments based on individual patient characteristics, genomics, and biomarkers to enhance the effectiveness of therapies. The objective is to describe the recent advancements in Critical Care Medicine...
March 9, 2024: World Journal of Critical Care Medicine
#37
REVIEW
Erin D Wieruszewski, Mariam ElSaban, Patrick M Wieruszewski, Nathan J Smischney
The discovery and utilization of volatile anesthetics has significantly transformed surgical practices since their inception in the mid-19th century. Recently, a paradigm shift is observed as volatile anesthetics extend beyond traditional confines of the operating theatres, finding diverse applications in intensive care settings. In the dynamic landscape of intensive care, volatile anesthetics emerge as a promising avenue for addressing complex sedation requirements, managing refractory lung pathologies including acute respiratory distress syndrome and status asthmaticus, conditions of high sedative requirements including burns, high opioid or alcohol use and neurological conditions such as status epilepticus...
March 9, 2024: World Journal of Critical Care Medicine
#38
Marjolein C de Jongh, Matthijs Bax, Khalil Ayan, Sakir Akin
BACKGROUND: The prone position is recommended as supportive therapy in patients with moderate-to-severe acute respiratory distress syndrome (ARDS). However, little is known about prone position ventilation in patients with cardiogenic shock supported by extracorporeal membrane oxygenation (ECMO) plus Impella (ECPELLA) developing ARDS. CASE SUMMARY: A 66-year-old man with severe left ventricular dysfunction was admitted to a non-academic ECMO centre for a high-risk coronary artery bypass grafting...
April 2024: European Heart Journal. Case Reports
#39
Jaquelyn Kakalecik, Amanda M Frantz, Michael T Talerico, Thomas A Krupko, Jennifer E Hagen, Matthew R Patrick
Extracorporeal membrane oxygenation (ECMO) has become a salvage therapy for patients with severe acute respiratory distress syndrome (ARDS). The management of orthopaedic trauma in ECMO-supported patients with ARDS remains an evolving area of interest. Orthopaedic injuries are often temporized with external fixators, skeletal traction, or splints due to hemodynamic instability as well as concerns of exacerbating underlying pulmonary injury. However, patients requiring ECMO support do not rely on their pulmonary system for oxygenation, the need for delayed fixation may not apply...
June 2024: Trauma Case Reports
#40
Yuki Yamafuji, Masafumi Suga, Seiya Fujisawa, Gentoku Oosuki, Takuya Taira, Ryo Takahashi, Shigenari Matsuyama, Satoshi Ishihara
Fat embolism syndrome (FES) is a rare complication of long bone fractures, with fulminant FES developing within 12 h of injury and often proving fatal (Shaikh, 2009 [1]). Here, we present a case of fulminant FES in a patient who developed sudden right heart failure after undergoing external fixation of a lower leg fracture and required veno-arterial extracorporeal membrane oxygenation (VA-ECMO). A 79-year-old woman injured in a traffic accident was transferred to our emergency department. Upon arrival, her level of consciousness deteriorated, and she developed circulatory failure...
June 2024: Trauma Case Reports
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