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journal of virology

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No abstract text is available yet for this article.
January 15, 2017: Journal of Virology
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2017: Journal of Virology
Rozanne M Sandri-Goldin
No abstract text is available yet for this article.
December 15, 2016: Journal of Virology
Frederik Graw, Alan S Perelson
The way in which a viral infection spreads within a host is a complex process that is not well understood. Different viruses, such as human immunodeficiency virus type 1 and hepatitis C virus, have evolved different strategies, including direct cell-to-cell transmission and cell-free transmission, to spread within a host. To what extent these two modes of transmission are exploited in vivo is still unknown. Mathematical modeling has been an essential tool to get a better systematic and quantitative understanding of viral processes that are difficult to discern through strictly experimental approaches...
September 29, 2016: Annual Review of Virology
Huldrych F Günthard, Michael S Saag, Constance A Benson, Carlos del Rio, Joseph J Eron, Joel E Gallant, Jennifer F Hoy, Michael J Mugavero, Paul E Sax, Melanie A Thompson, Rajesh T Gandhi, Raphael J Landovitz, Davey M Smith, Donna M Jacobsen, Paul A Volberding
IMPORTANCE: New data and therapeutic options warrant updated recommendations for the use of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults. OBJECTIVE: To provide updated recommendations for the use of antiretroviral therapy in adults (aged ≥18 years) with established HIV infection, including when to start treatment, initial regimens, and changing regimens, along with recommendations for using ARVs for preventing HIV among those at risk, including preexposure and postexposure prophylaxis...
July 12, 2016: JAMA: the Journal of the American Medical Association
Karina Butler, Jamie Inshaw, Deborah Ford, Sarah Bernays, Karen Scott, Julia Kenny, Nigel Klein, Anna Turkova, Lynda Harper, Eleni Nastouli, Sara Paparini, Rahela Choudhury, Tim Rhodes, Abdel Babiker, Diana Gibb
BACKGROUND: For human immunodeficiency virus (HIV)-infected adolescents facing lifelong antiretroviral therapy (ART), short-cycle therapy (SCT) with long-acting agents offers the potential for drug-free weekends, less toxicity, better adherence and cost savings. OBJECTIVES: To determine whether or not efavirenz (EFV)-based ART in short cycles of 5 days on and 2 days off is as efficacious (in maintaining virological suppression) as continuous EFV-based ART (continuous therapy; CT)...
June 2016: Health Technology Assessment: HTA
Zhengting Wang, Yongdi Chen, Gaofeng Cai, Zhenggang Jiang, Kui Liu, Bin Chen, Jianmin Jiang, Hua Gu
Middle East Respiratory Syndrome (MERS), a pandemic threat to human beings, has aroused huge concern worldwide, but no bibliometric studies have been conducted on MERS research. The aim of this study was to map research productivity on the disease based on the articles indexed in PubMed. The articles related to MERS dated from 2012 to 2015 were retrieved from PubMed. The articles were classified into three categories according to their focus. Publication outputs were assessed and frequently used terms were mapped using the VOS viewer software...
2016: International Journal of Environmental Research and Public Health
Ehsan Aminizadeh, Seyed Moayyed Alavian, Ali Akbari Sari, Nasser Ebrahimi Daryani, Bita Behnava
CONTEXT: Hepatitis C virus (HCV) infection is a major cause of liver-morbidity and mortality among patients with thalassemia. Peginterferon plus ribavirin is currently the recommended therapy for hepatitis C infection in patients do not have thalassemia, but using ribavirin in patients with thalassemia is restricted due to its hemolytic effect. To evaluate the efficacy and safety of adding ribavirin to peginterferon or interferon, authors performed a systematic review on the available literatures...
March 2016: Hepatitis Monthly
Andrew Blann, Brian Nation
In 2015, the British Journal of Biomedical Science published 47 reports on topics relating to the various disciplines within biomedical science. Of these, the majority were in infection science (15 in microbiology and two in virology) and blood science (seven in biochemistry, four in haematology, three in immunology and one in transplantation), with a smaller number in cellular sciences (four reports) and with one review across disciplines. The present report will summarise key aspects of these publications that are of greatest relevance to laboratory scientists...
2016: British Journal of Biomedical Science
Nimer Assy, Masad Barhoum
No abstract text is available yet for this article.
April 28, 2016: New England Journal of Medicine
Graham R Foster, Alessandra Mangia, Mark Sulkowski
No abstract text is available yet for this article.
April 28, 2016: New England Journal of Medicine
Fengyun Yi, Pin Yang, Huifeng Sheng
BACKGROUND: Ebola virus disease (hereafter EVD or Ebola) has a high fatality rate. The devastating effects of the current epidemic of Ebola in West Africa have put the global health response in acute focus. In response, the World Health Organization (WHO) has declared the Ebola outbreak in West Africa as a "Public Health Emergency of International Concern". A small proportion of scientific literature is dedicated to Ebola research. METHODS: To identify global research trends in Ebola research, the Institute for Scientific Information (ISI) Web of Science™ database was used to search for data, which encompassed original articles published from 1900 to 2013...
April 15, 2016: BMC Research Notes
Nicholas I Paton, Wolfgang Stöhr, Lars Oddershede, Alejandro Arenas-Pinto, Simon Walker, Mark Sculpher, David T Dunn
BACKGROUND: Standard-of-care antiretroviral therapy (ART) for human immunodeficiency virus (HIV) infection uses a combination of drugs, until now considered essential to minimise treatment failure and development of drug resistance. Protease inhibitors (PIs) are potent with a high genetic barrier to resistance and have the potential for use as monotherapy after viral load (VL) suppression achieved on combination therapy. However, longer-term resistance and toxicity risks are uncertain...
March 2016: Health Technology Assessment: HTA
(no author information available yet)
The article "Immune memory responses to HBV vaccine 13-18 years after primary vaccination" by L. Hou, W. Li, X. Wei, Y. Zhou, Y. Zhuo, H. Wu, B. Shen published in 2015 in Genetics and Molecular Research 14(3): 8466-8472 ( has been found to be substantially equal to the article "Immune memory response induced in vitro by recombinant hepatitis B surface antigen challenge 13-18 years after primary vaccination" published in the Journal of Medical Virology 86:1700-1704 (2014) from Andrea do Livramento et al...
2016: Genetics and Molecular Research: GMR
Linfa Wang
The editors of Virology Journal would like to thank all our reviewers who have contributed to the journal in Volume 12 (2015). The success of any scientific journal depends on an effective and strict peer review process and Virology Journal could not operate without your contribution.Our record time from submission to online, open access, publication in 2015 was 36 days for a Research Article (Virol J 12:107, 2015). This is a great achievement by any standard. We look forward to your continuous support of Virology Journal either as an invited reviewer or a contributing author in the years to come...
2016: Virology Journal
Leonard W Seymour, Kerry D Fisher
Oncolytic viruses can be found at the confluence of virology, genetic engineering and pharmacology where versatile platforms for molecularly targeted anticancer agents can be designed and optimised. Oncolytic viruses offer several important advantages over traditional approaches, including the following. (1) Amplification of the active agent (infectious virus particles) within the tumour. This avoids unnecessary exposure to normal tissues experienced during delivery of traditional stoichiometric chemotherapy and maximises the therapeutic index...
February 16, 2016: British Journal of Cancer
Robin A Weiss
No abstract text is available yet for this article.
December 2015: Journal of General Virology
Susanna K P Lau, Jasper F W Chan
The severe acute respiratory syndrome coronavirus (SARS-CoV) and recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV) epidemics have proven the ability of coronaviruses to cross species barrier and emerge rapidly in humans. Other coronaviruses such as porcine epidemic diarrhea virus (PEDV) are also known to cause major disease epidemics in animals with huge economic loss. This special issue in Virology Journal aims to highlight the advances and key discoveries in the animal origin, viral evolution, epidemiology, diagnostics and pathogenesis of the emerging and re-emerging coronaviruses in both humans and animals...
December 22, 2015: Virology Journal
Yin Xu, Peng Huang, Ming Yue, Jing Su, Hongbo Chen, Mingzhu Chen, Jie Wang, Jun Li, Zhihang Peng, Yun Zhang, Rongbin Yu
A recent genome-wide association study (GWAS) has identified the single-nucleotide polymorphism (SNP) rs4273729 in a 100-kbp region comprising human leukocyte antigens (HLAs) class II genes as an important predictor of hepatitis C virus (HCV) clearance in European and African populations. This study was to determine whether this polymorphism is also associated with spontaneous HCV clearance as well as response to interferon treatment in Chinese patients. Thus, 686 chronic HCV carriers, 432 individuals with spontaneous viral clearance and 243 patients with pegylated interferon-α and ribavirin (PEG IFN-α/RBV) treatment were genotyped...
April 2016: Journal of Human Genetics
Julian Ruiz-Saenz, Marlen Martinez-Gutierrez
INTRODUCTION: Bibliometric analysis demonstrates that the virology research in Latin America has increased. For this reason, the objective of this study was to evaluate Colombian publications on viruses and viral diseases in indexed journals during the period from 2000 to 2013. METHODOLOGY: The bibliographic data were collected from MedLine, SciELO, LILACS and Scopus databases. The database was constructed in Excel descriptive statistics. The SCImago Journal Rank (SJR) was evaluated using the SCImago Journal & Country Rank in 2013 and was used as an indicator of the quality of the journals used by the Colombian researchers...
November 30, 2015: Journal of Infection in Developing Countries
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