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https://www.readbyqxmd.com/read/28922767/photosynthetic-and-metabolic-acclimation-to-repeated-drought-events-play-key-roles-in-drought-tolerance-in-coffee
#1
Paulo E Menezes-Silva, Lilian M V P Sanglard, Rodrigo T Ávila, Leandro E Morais, Samuel C V Martins, Priscilla Nobres, Camila M Patreze, Marcio A Ferreira, Wagner L Araújo, Alisdair R Fernie, Fábio M DaMatta
Over the last decades, most information on the mechanisms underlying tolerance to drought has been gained by considering this stress as a single event that happens just once in the life of a plant, in contrast to what occurs under natural conditions where recurrent drought episodes are the rule. Here we explored mechanisms of drought tolerance in coffee (Coffea canephora) plants from a broader perspective, integrating key aspects of plant physiology and biochemistry. We show that plants exposed to multiple drought events displayed higher photosynthetic rates, which were largely accounted for by biochemical rather than diffusive or hydraulic factors, than those submitted to drought for the first time...
July 10, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28921675/altered-cav1-2-function-in-the-timothy-syndrome-mouse-model-produces-ascending-serotonergic-abnormalities
#2
Daniel G Ehlinger, Kathryn G Commons
Polymorphism in the gene CACNA1C, encoding the pore-forming subunit of Cav1.2 L-type calcium channels, has one of the strongest genetic linkages to schizophrenia, bipolar disorder, and major depressive disorder: psychopathologies in which serotonin signaling has been implicated. Additionally, a gain-of-function mutation in CACNA1C is responsible for the neurodevelopmental disorder Timothy Syndrome that presents with prominent behavioral features on the autism spectrum. Given an emerging role for serotonin in the etiology of autism spectrum disorders, we investigate the relationship between Cav1...
September 16, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28921474/origins-of-phantom-limb-pain
#3
Damien P Kuffler
Phantom limb pain (PLP) is a chronic neuropathic pain occurring in 45-85% of patients who undergo major amputations of the upper and lower extremities. Chronic pain is physically and mentally debilitating, affecting an individual's potential for self-care and the performance of daily living activities essential for personal and economic independence. In addition, chronic pain may lead to depression and feelings of hopelessness. A National Center for Biotechnology Information study found that in the USA alone, the annual cost of dealing with neuropathic pain is more than $600 billion, with an estimated 20 million people in the USA suffering this condition...
September 18, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28921418/coping-with-phantom-limb-pain
#4
Damien P Kuffler
Phantom limb pain is a chronic neuropathic pain that develops in 45-85% of patients who undergo major amputations of the upper and lower extremities and appears predominantly during two time frames following an amputation: the first month and later about 1 year. Although in most patients the frequency and intensity of pain diminish over time, severe pain persists in about 5-10%. It has been proposed that factors in both the peripheral and central nervous systems play major roles in triggering the development and maintenance of pain associated with extremity amputations...
September 18, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28919135/are-experiences-of-discrimination-related-to-poorer-dietary-intakes-among-south-asians-in-the-masala-study
#5
Sarah Nadimpalli, Akilah Keita, Jeremy Wang, Alka Kanaya, Namratha Kandula, Kimberly Gans, Sameera Talegawkar
OBJECTIVE: To examine associations between self-reported discrimination and dietary intakes among South Asian (SA) people. METHODS: Data from the Mediators of Atherosclerosis in South Asians Living in America study were used to analyze the relationship between self-reported discrimination and dietary behaviors (n = 866). Self-reported discrimination was measured with the 9-item continuous Everyday Discrimination Scale. Diet was measured with a culturally tailored, validated, 163-item food frequency questionnaire for SA individuals...
September 14, 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/28918460/effects-of-cadmium-exposure-on-metal-accumulation-and-energy-metabolism-of-silver-carp-hypophthalmichthys-molitrix
#6
Deliang Li, Jie Pi, Jianping Wang, Pengfei Zhu, Deming Liu, Ting Zhang
Effects of cadmium (Cd) exposure on metal accumulation and energy metabolism of silver carp (Hypophthalmichthys molitrix) were studied during 14 days. The results showed that Cd accumulated in tissues of silver carp significantly with time and Cd concentration, as the order: liver > kidney > gill > muscle. The levels of muscle glycogen, triglyceride, and plasma triglyceride decreased significantly (p < 0.05). The levels of muscle protein, plasma glucose and lactate significantly increased during the first 8 days, and then all significantly decreased (p < 0...
September 16, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28916265/glycans-function-as-anchors-for-antibodies-and-help-drive-hiv-broadly-neutralizing-antibody-development
#7
Raiees Andrabi, Ching-Yao Su, Chi-Hui Liang, Sachin S Shivatare, Bryan Briney, James E Voss, Salar Khan Nawazi, Chung-Yi Wu, Chi-Huey Wong, Dennis R Burton
Apex broadly neutralizing HIV antibodies (bnAbs) recognize glycans and protein surface close to the 3-fold axis of the envelope (Env) trimer and are among the most potent and broad Abs described. The evolution of apex bnAbs from one donor (CAP256) has been studied in detail and many Abs at different stages of maturation have been described. Using diverse engineering tools, we investigated the involvement of glycan recognition in the development of the CAP256.VRC26 Ab lineage. We found that sialic acid-bearing glycans were recognized by germline-encoded and somatically mutated residues on the Ab heavy chain...
September 8, 2017: Immunity
https://www.readbyqxmd.com/read/28913979/physical-pain-increases-interpersonal-trust-in-females
#8
C Wang, J Gao, Y Ma, C Zhu, X-W Dong
BACKGROUND: People behave and interact with others differently when experiencing physical pain. Pain has dramatic effects on one's emotional responses, cognitive functions and social interaction. However, little has been known about whether and how physical pain influences interpersonal trust in social interaction. In the present study, we examined the influence of physical pain on trusting behaviour. METHODS: A total of 112 healthy participants were recruited and assigned to physical pain condition (induced by Capsaicin) and control condition (with hand cream), respectively...
September 14, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28913895/nramp2-a-trans-golgi-network-localized-manganese-transporter-is-required-for-arabidopsis-root-growth-under-manganese-deficiency
#9
Huiling Gao, Wenxiang Xie, Changhong Yang, Jingyi Xu, Jingjun Li, Hua Wang, Xi Chen, Chao-Feng Huang
To cope with manganese (Mn) deficiency, plants have evolved an efficient transport system to uptake and redistribute Mn. However, the underlying molecular mechanisms remain to be demonstrated. We carried out a forward genetic screen in a root high-affinity Mn transporter nramp1 mutant background in Arabidopsis thaliana and identified an uncharacterized Mn transport NRAMP2. We investigated the effect of nramp2 mutation on root growth and reactive oxygen species (ROS) accumulation and we also examined the NRAMP2 expression pattern, and the subcellular localization and transport activity of NRAMP2...
September 15, 2017: New Phytologist
https://www.readbyqxmd.com/read/28912799/triportheus-albus-cope-1872-in-the-blackwater-clearwater-and-whitewater-of-the-amazon-a-case-of-phenotypic-plasticity
#10
José D A Araújo, Andrea Ghelfi, Adalberto L Val
The Amazon basin includes 1000s of bodies of water, that are sorted according to their color in three types: blackwater, clearwater, and whitewater, which significantly differ in terms of their physicochemical parameters. More than 3,000 species of fish live in the rivers of the Amazon, among them, the sardine, Triportheus albus, which is one of the few species that inhabit all three types of water. The purpose of our study was to analyze if the gene expression of T. albus is determined by the different types of water, that is, if the species presents phenotypic plasticity to live in blackwater, clearwater, and whitewater...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/28910765/multiple-semantic-matching-on-augmented-n-partite-graph-for-object-co-segmentation
#11
Chuan Wang, Hua Zhang, Liang Yang, Xiaochun Cao, Hongkai Xiong
Recent methods for object co-segmentation focus on discovering single co-occurring relation of candidate regions representing the foreground of multiple images. However, region extraction based only on low and middle level information often occupies a large area of background without the help of semantic context. In addition, seeking single matching solution very likely leads to discover local parts of common objects. To cope with these deficiencies, we present a new object cosegmentation framework, which takes advantages of semantic information and globally explores multiple co-occurring matching cliques based on an N-partite graph structure...
September 8, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28902052/overcoming-education-failures-and-retakes-a-spiritual-process
#12
Stephanie T Wynn
The retention of students is a major challenge for nursing education programs. Although students who fail can often retake courses, negative internalities may occur. After a failure, students regularly present with emotional distress. A mental health practitioner, who is a nursing faculty member, is ideal to assist these students and offer support. The integration of spirituality as a coping mechanism for these students can serve as a protective factor.
October 2017: Journal of Christian Nursing: a Quarterly Publication of Nurses Christian Fellowship
https://www.readbyqxmd.com/read/28900680/coordinating-organismal-metabolism-during-protein-misfolding-in-the-er-through-the-unfolded-protein-response
#13
Vishwanatha K Chandrahas, Jaeseok Han, Randal J Kaufman
The endoplasmic reticulum (ER) is a cellular organelle responsible for folding of secretory and membrane proteins. Perturbance in ER homeostasis caused by various intrinsic/extrinsic stimuli challenges the protein-folding capacity of the ER, leading to an ER dysfunction, called ER stress. Cells have developed a defensive response to adapt and/or survive in the face of ER stress that may be detrimental to cell function and survival. When exposed to ER stress, the cell activates a complex and elaborate signaling network that includes translational modulation and transcriptional induction of genes...
September 13, 2017: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/28900256/genomic-and-transcriptomic-analysis-of-the-toluene-degrading-black-yeast-cladophialophora-immunda
#14
Barbara Blasi, Hakim Tafer, Christina Kustor, Caroline Poyntner, Ksenija Lopandic, Katja Sterflinger
Cladophialophora immunda is an ascomycotal species belonging to the group of the black yeasts. These fungi have a thick and melanized cell wall and other physiological adaptations that allows them to cope with several extreme physical and chemical conditions. Member of the group can colonize some of the most extremophilic environments on Earth. Cladophialophora immunda together with a few other species of the order Chaetothyriales show a special association with hydrocarbon polluted environments. The finding that the fungus is able to completely mineralize toluene makes it an interesting candidate for bioremediation purposes...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28899829/multi-scale-mechanical-characterization-of-prostate-cancer-cell-lines-relevant-biological-markers-to-evaluate-the-cell-metastatic-potential
#15
J Zouaoui, A M Trunfio-Sfarghiu, L Brizuela, A Piednoir, O Maniti, B Munteanu, S Mebarek, A Girard-Egrot, A Landoulsi, T Granjon
BACKGROUND: Considering the importance of cellular mechanics in the birth and evolution of cancer towards increasingly aggressive stages, we compared nano-mechanical properties of non-tumoral (WPMY-1) and highly aggressive metastatic (PC-3) prostate cell lines both on cell aggregates, single cells, and membrane lipids. METHODS: Cell aggregate rheological properties were analyzed during dynamic compression stress performed on a homemade rheometer. Single cell visco-elasticity measurements were performed by Atomic Force Microscopy using a cantilever with round tip on surface-attached cells...
September 9, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28899584/evaluating-the-past-to-improve-the-future-a-qualitative-study-of-icu-patients-experiences
#16
Kristin Dahle Olsen, Marit Nester, Britt Sætre Hansen
BACKGROUND: The recovery period for patients who have been in an intensive care unitis often prolonged and suboptimal. Anxiety, depression and post-traumatic stress disorder are common psychological problems. Intensive care staff offer various types of intensive aftercare. Intensive care follow-up aftercare services are not standard clinical practice in Norway. OBJECTIVE: The overall aim of this study is to investigate how adult patients experience theirintensive care stay their recovery period, and the usefulness of an information pamphlet...
September 9, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28898859/antibacterial-clay-against-gram-negative-antibiotic-resistant-bacteria
#17
Luis Zarate-Reyes, Cynthia Lopez-Pacheco, Antonio Nieto-Camacho, Eduardo Palacios, Virginia Gómez-Vidales, Stephan Kaufhold, Kristian Ufer, Eduardo García Zepeda, Javiera Cervini-Silva
Antibiotic resistant bacteria persist throughout the world because they have evolved the ability to express various defense mechanisms to cope with antibiotics and the immune system; thus, low-cost strategies for the treatment of these bacteria are needed, such as the usage of environmental minerals. This paper reports the antimicrobial properties of a clay collected from Brunnenberg, Germany, that is composed of ferroan saponite with admixtures of quartz, feldspar and calcite as well as exposed or hidden (layered at inner regions) nano Fe(0)...
September 1, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28898654/plant-cell-walls
#18
Herman Höfte, Aline Voxeur
Plants are able to generate large leaf surfaces that act as two-dimensional solar panels with a minimum investment in building material, thanks to a hydrostatic skeleton. This requires high intracellular pressures (up to 1 MPa), which depend on the presence of strong cell walls. The walls of growing cells (also called primary walls), are remarkably able to reconcile extreme tensile strength (up to 100 MPa) with the extensibility necessary for growth. All walled organisms are confronted with this dilemma - the need to balance strength and extensibility - and bacteria, fungi and plants have evolved independent solutions to cope...
September 11, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28898109/factors-associated-with-type-ii-trauma-in-occupational-groups-working-with-traumatised-children-a-systematic-review
#19
Clara A M Sage, Samantha K Brooks, Neil Greenberg
BACKGROUND: There is evidence that "Type II trauma" (TTT) - repeated exposure to traumatic events - can lead to the development of post-traumatic stress disorder (PTSD). TTT frequently occurs in occupational groups working with children who are themselves victims of trauma. AIM: To conduct a systematic review identifying risk factors for/protective factors against TTT-associated mental ill-health in employees working with traumatised children and explore how this type of work impacts upon social functioning...
September 12, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28895988/pain-in-women
#20
Inna Belfer
Men and women are different in response to experimental painful stimulation, in pain attitude such as reporting pain and pain coping behavior, in symptoms and signs of painful disorders and in response to pain treatment. Both acute and chronic pain conditions have diverse prevalence among the sexes. Overall, women have more than twice higher prevalence in painful disorders compared to men. Here I review putative mechanisms underlying sex differences in pain, including genetic factors that have sex-specific or sex-biased effects controlling pain and analgesia...
April 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
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