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https://www.readbyqxmd.com/read/29040557/divergence-and-convergence-in-cause-specific-premature-adult-mortality-in-mexico-and-us-mexican-hispanics-from-1995-to-2015-analyses-of-4-9-million-individual-deaths
#1
Luz Myriam Reynales-Shigematsu, Carlos Manuel Guerrero-López, Mauricio Hernández Ávila, Hyacinth Irving, Prabhat Jha
Background: Mexicans and US Mexican Hispanics share modifiable determinants of premature mortality. We compared trends in mortality at ages 30-69 in Mexico and among US Mexican Hispanics from 1995 to 2015. Methods: We examined nationally representative statistics on 4.2 million Mexican and 0.7 million US deaths to examine cause-specific mortality. We used lung cancer indexed methods to estimate smoking-attributable deaths stratified by high and lower burden Mexican states...
September 23, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29034955/a-review-of-issues-of-nomenclature-and-taxonomy-of-hypericum-perforatum-l-and-kew-s-medicinal-plant-names-services
#2
REVIEW
Elizabeth Anne Dauncey, Jason Thomas Whitley Irving, Robert Allkin
OBJECTIVES: To review which names are used to refer to Hypericum perforatum L. in health regulation and medicinal plant references, and the potential for ambiguity or imprecision. KEY FINDINGS: Structured searches of Kew's Medicinal Plant Names Services Resource, supplemented with other online bibliographic resources, found that the scientific name Hypericum perforatum L. is used consistently in the literature, but variation between subspecies is rarely considered by researchers...
October 16, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/29033043/in%C3%A2-vivo-lung-perfusion-rehabilitates-sepsis-induced-lung-injury
#3
J Hunter Mehaffey, Eric J Charles, Sarah Schubert, Morgan Salmon, Ashish K Sharma, Dustin Money, Mark H Stoler, Victor E Laubach, Curtis G Tribble, Mark E Roeser, Irving L Kron
BACKGROUND: Sepsis is the leading cause of lung injury in adults and can lead to acute respiratory distress syndrome (ARDS). Using a novel technique of isolated in vivo lung perfusion (IVLP), we hypothesized that normothermic IVLP will improve oxygenation and compliance in a porcine model of sepsis-induced lung injury. METHODS: Mature adult swine (n = 8) were administered lipopolysaccharide (LPS; 50 μg/kg over 2 hours) via the external jugular vein, followed by sternotomy and central extracorporeal membrane oxygenation (ECMO) cannulation (right atrium to ascending aorta)...
September 14, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29032725/percutaneous-pedestals-in-cochlear-implantation
#4
Alistair Mitchell-Innes, Richard Irving, Robert Briggs
Percutaneous pedestals have been integral to the development of cochlear implants since 1969. By enabling direct electrical access to implanted electrodes or other devices, they allow optimization of control of stimulation strategies. Similarly, technology not validated for implantable use can be safely tested. These advantages have facilitated the development of cochlear implants and also resulted in their inclusion in trials investigating electronic implants developed for other organs. Surgery is straightforward, but post-operative care, in particular, skin-care is crucial to ensure complications are minimized...
October 16, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/29029272/bsr-and-bhpr-guideline-for-the-prescription-and-monitoring-of-non-biologic-disease-modifying-anti-rheumatic-drugs
#5
Jo Ledingham, Nicola Gullick, Katherine Irving, Rachel Gorodkin, Melissa Aris, Jean Burke, Patrick Gordon, Dimitrios Christidis, Sarah Galloway, Eranga Hayes, Andrew Jeffries, Scott Mercer, Janice Mooney, Sander van Leuven, James Galloway
No abstract text is available yet for this article.
September 28, 2017: Rheumatology
https://www.readbyqxmd.com/read/29029064/2015-2016-vaccine-effectiveness-of-live-attenuated-and-inactivated-influenza-vaccines-in-children-in-the-united-states
#6
Katherine A Poehling, Herve Caspard, Timothy R Peters, Edward A Belongia, Blaise Congeni, Manjusha Gaglani, Marie R Griffin, Stephanie A Irving, Poornima K Kavathekar, Huong Q McLean, Allison L Naleway, Kathleen Ryan, H Keipp Talbot, Christopher S Ambrose
Background: In the 2015-2016 season, quadrivalent live attenuated influenza vaccine (LAIV) and both trivalent and quadrivalent inactivated influenza vaccine (IIV) were available in the United States. Methods: This study, conducted according to a test-negative case-control design, enrolled children aged 2-17 years presenting to outpatient settings with fever and respiratory symptoms for <5 days at 8 sites across the United States between November 30, 2015 and April 15, 2016...
October 4, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29020505/socioecological-factors-related-to-hazardous-alcohol-use-among-female-sex-workers-in-lilongwe-malawi-a-mixed-methods-study
#7
Kathryn E Lancaster, Sarah A MacLean, Thandie Lungu, Pearson Mmodzi, Mina C Hosseinipour, Rebecca B Hershow, Kimberly A Powers, Brian W Pence, Irving F Hoffman, William C Miller, Vivian F Go
BACKGROUND: Alcohol use is pervasive among female sex workers (FSW) placing them at increased risk of violence and sexual risk behaviors. FSW often live and work where alcohol is highly normative. OBJECTIVE: To understand the socioecological influences on hazardous alcohol use among FSW in Malawi. METHODS: In 2014, 200 FSW identified through venue-based sampling in Lilongwe, Malawi, completed a quantitative behavioral survey, with a sub-sample participating in qualitative interviews...
October 11, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28993512/loss-of-nlrx1-exacerbates-neural-tissue-damage-and-nf-%C3%AE%C2%BAb-signaling-following-brain-injury
#8
Michelle H Theus, Thomas Brickler, Armand L Meza, Sheryl Coutermarsh-Ott, Amanda Hazy, Denis Gris, Irving C Allen
Traumatic and nontraumatic brain injury results from severe disruptions in the cellular microenvironment leading to massive loss of neuronal populations and increased neuroinflammation. The progressive cascade of secondary events, including ischemia, inflammation, excitotoxicity, and free-radical release, contribute to neural tissue damage. NLRX1 is a member of the NLR family of pattern recognition receptors and is a potent negative regulator of several pathways that significantly modulate many of these events...
October 9, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28993261/volatile-organic-compounds-in-feces-associate-with-response-to-dietary-intervention-in-patients-with-irritable-bowel-syndrome
#9
Megan Rossi, Raphael Aggio, Heidi M Staudacher, Miranda C Lomer, James O Lindsay, Peter Irving, Chris Probert, Kevin Whelan
BACKGROUND & AIMS: Dietary interventions are effective in management of patients with irritable bowel syndrome (IBS), although responses vary. We investigated whether fecal levels of volatile organic compounds (VOCs) associate with response to dietary interventions in patients with IBS. METHODS: Adults who fulfilled the Rome III criteria for IBS were recruited to a 2x2 factorial randomized controlled trial. Patients were randomly assigned to a group counselled to follow a diet low in fructans, galacto-oligosaccharides, lactose, fructose, and polyols (low-FODMAP diet, n=46) or a group that received placebo dietary advice (sham diet, n=47) for 4 weeks...
October 6, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28991066/defense-automated-neurobehavioral-assessment-accurately-measures-cognition-in-patients-undergoing-electroconvulsive-therapy-for-major-depressive-disorder
#10
Kristen R Hollinger, Steven R Woods, Alexis Adams-Clark, So Yung Choi, Caroline L Franke, Ryoko Susukida, Carol Thompson, Irving M Reti, Adam I Kaplin
OBJECTIVES: The Defense Automated Neurobehavioral Assessment (DANA) is an electronic cognitive test battery. The present study compares DANA to the standard Mini-Mental State Examination (MMSE) in subjects undergoing electroconvulsive therapy for the treatment of major depressive disorder. METHODS: Seventeen inpatient subjects in the Johns Hopkins Hospital Department of Psychiatry were administered longitudinal paired DANA and MMSE tests (7.6 ± 4.1 per patient) from January 10, 2014 to September 26, 2014...
October 3, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28989194/effective-dementia-education-and-training-for-the-health-and-social-care-workforce-a-systematic-review-of-the-literature
#11
Claire A Surr, Cara Gates, Donna Irving, Jan Oyebode, Sarah Jane Smith, Sahdia Parveen, Michelle Drury, Alison Dennison
Ensuring an informed and effective dementia workforce is of international concern; however, there remains limited understanding of how this can be achieved. This review aimed to identify features of effective dementia educational programs. Critical interpretive synthesis underpinned by Kirkpatrick's return on investment model was applied. One hundred and fifty-two papers of variable quality were included. Common features of more efficacious educational programs included the need for educational programs to be relevant to participants' role and experience, involve active face-to-face participation, underpin practice-based learning with theory, be delivered by an experienced facilitator, have a total duration of at least 8 hours with individual sessions of 90 minutes or more, support application of learning in practice, and provide a structured tool or guideline to guide care practice...
October 2017: Review of Educational Research
https://www.readbyqxmd.com/read/28982718/contemporary-outcomes-in-reoperative-mitral-valve-surgery
#12
Hunter J Mehaffey, Robert B Hawkins, Sarah Schubert, Clifford Fonner, Leora T Yarboro, Mohammed Quader, Alan Speir, Jeff Rich, Irving L Kron, Gorav Ailawadi
OBJECTIVE: Data suggest that redo mitral valve surgery is being performed in increasing numbers, possibly with superior results according to single-centre studies. The purpose of this study is to describe outcomes of redo mitral valve surgery and identify risk-adjusted predictors of poor outcomes. METHODS: All (11 973) open mitral valve cases were evaluated (2002-2016) from a regional Society of Thoracic Surgery (STS) database. Patients were stratified by primary versus redo mitral valve surgery...
October 5, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28978794/delivery-of-monocyte-lineage-cells-in-a-biomimetic-scaffold-enhances-tissue-repair
#13
Michael S Hu, Graham G Walmsley, Leandra A Barnes, Kipp Weiskopf, Robert C Rennert, Dominik Duscher, Michael Januszyk, Zeshaan N Maan, Wan Xing Hong, Alexander Tm Cheung, Tripp Leavitt, Clement D Marshall, Ryan C Ransom, Samir Malhotra, Alessandra L Moore, Jayakumar Rajadas, H Peter Lorenz, Irving L Weissman, Geoffrey C Gurtner, Michael T Longaker
The monocyte lineage is essential to normal wound healing. Macrophage inhibition or knockout in mice results in impaired wound healing through reduced neovascularization, granulation tissue formation, and reepithelialization. Numerous studies have either depleted macrophages or reduced their activity in the context of wound healing. Here, we demonstrate that by increasing the number of macrophages or monocytes in the wound site above physiologic levels via pullulan-collagen composite dermal hydrogel scaffold delivery, the rate of wound healing can be significantly accelerated in both wild-type and diabetic mice, with no adverse effect on the quality of repair...
October 5, 2017: JCI Insight
https://www.readbyqxmd.com/read/28978289/-we-have-heard-it-together-a-qualitative-analysis-of-couple-hiv-testing-and-counselling-recruitment-in-malawi-s-option-b-programme
#14
Nora E Rosenberg, Rebecca Gross, Tiwonge Mtande, Suzanne Maman, Carol E Golin, Friday Saidi, Olivia Manthalu, Irving Hoffman, Mina C Hosseinipour, William C Miller
Encouraging HIV-infected pregnant women to recruit male partners for couple HIV testing and counselling (CHTC) is promoted by the World Health Organization, but remains challenging. Formal strategies for recruiting the male partners of pregnant women have not been explored within an Option B+ programme. Our objective was to learn about experiences surrounding CHTC recruitment within a formal CHTC recruitment study. A randomised controlled trial comparing two CHTC recruitment strategies was conducted among HIV-infected pregnant women presenting to Bwaila Antenatal Unit in 2014...
September 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/28977997/expression-of-hypothalamic-neurohormones-and-their-receptors-in-the-human-eye
#15
Sander R Dubovy, Maria P Fernandez, Jose J Echegaray, Norman L Block, Noriyuki Unoki, Roberto Perez, Irving Vidaurre, Richard K Lee, Mehrdad Nadji, Andrew V Schally
Extrapituitary roles for hypothalamic neurohormones have recently become apparent and clinically relevant, based on the use of synthetic peptide analogs for the treatment of multiple conditions including cancers, pulmonary edema and myocardial infarction. In the eye, it has been suggested that some of these hormones and their receptors may be present in the ciliary body, iris, trabecular meshwork and retina, but their physiological role has yet to be elucidated. Our study intends to comprehensively demonstrate the expression of some hypothalamic neuroendocrine hormones and their receptors within different retinal and extraretinal structures of the human eye...
September 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28977562/short-term-preoperative-exercise-training-should-we-expect-long-term-benefits-without-postoperative-exercise-stimulus
#16
Vinicius Cavalheri, Catherine L Granger, Louis B Irving, Daniel A Galvão
No abstract text is available yet for this article.
August 2, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28971977/human-lung-branching-morphogenesis-is-orchestrated-by-the-spatio-temporal-distribution-of-acta2-sox2-and-sox9
#17
Soula Danopoulos, Irving Alonso, Matthew Thornton, Brendan Grubbs, Saverio Bellusci, David Warburton, Denise Al Alam
Lung morphogenesis relies on a number of important processes including proximal-distal patterning, cell proliferation, migration and differentiation, as well as epithelial-mesenchymal interactions. In mouse lung development, SOX2+ cells are localized in the proximal epithelium whereas SOX9+ cells are present in the distal epithelium. We show that in human lung, expression of these transcription factors differs, in that during the pseudoglandular stage distal epithelial progenitors at the tips co-express SOX2 and SOX9...
September 28, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28969355/intensive-case-management-for-severe-mental-illness
#18
Marina Dieterich, Claire B Irving, Hanna Bergman, Mariam A Khokhar, Bert Park, Max Marshall
No abstract text is available yet for this article.
July 1, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28962608/benefits-of-home-based-multidisciplinary-exercise-and-supportive-care-in-inoperable-non-small-cell-lung-cancer-protocol-for-a-phase-ii-randomised-controlled-trial
#19
Lara Edbrooke, Sanchia Aranda, Catherine L Granger, Christine F McDonald, Mei Krishnasamy, Linda Mileshkin, Louis Irving, Sabine Braat, Ross A Clark, Ian Gordon, Linda Denehy
BACKGROUND: Lung cancer is one of the most commonly diagnosed cancers, and is a leading cause of cancer mortality world-wide. Due to lack of early specific symptoms, the majority of patients present with advanced, inoperable disease and five-year relative survival across all stages of non-small cell lung cancer (NSCLC) is 14%. People with lung cancer also report higher levels of symptom distress than those with other forms of cancer. Several benefits for survival and patient reported outcomes are reported from physical activity and exercise in other tumour groups...
September 29, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28953450/enhanced-immune-response-to-rabies-viruses-by-the-use-of-a-liposome-adjuvant-in-vaccines
#20
Li Miao, Yi Yang, Mingkun Yan, Yanchun Li, Jieshu Zhao, Jieshi Guo, Dong Zheng
Essen regimen, the Thai Red Cross two-site ID regimen, Zagreb schedule, and the eight-site ID regimen are the standard rabies vaccines recommended by the World Health Organization (WHO). In this study, a liposomal rabies vaccine (LipoRV) was developed, which was found to facilitate the production of rabies virus neutralizing antibody (RVNA) in BALB/c mice. Liposome solution was prepared with hydrogenated soya phosphatide and cholesterol. LipoRV composed of liposome solution and inactivated rabies vaccine (IRV)...
September 27, 2017: Viral Immunology
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