Shotaro Harada, Yoshihisa Koyama, Takao Imai, Yoshichika Yoshioka, Takuya Sumi, Hidenori Inohara, Shoichi Shimada
Autoimmune inner ear disease (AIED) is an organ-specific disease characterized by irreversible, prolonged, and progressive hearing and equilibrium dysfunctions. The primary symptoms of AIED include asymmetric sensorineural hearing loss accompanied by vertigo, aural fullness, and tinnitus. AIED is divided into primary and secondary types. Research has been conducted using animal models of rheumatoid arthritis (RA), a cause of secondary AIED. However, current models are insufficient to accurately analyze vestibular function, and the mechanism underlying the onset of AIED has not yet been fully elucidated...
April 24, 2024: Biochimica et Biophysica Acta. Molecular Basis of Disease