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Endolymphatic hydrops

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https://www.readbyqxmd.com/read/28449168/mri-sequences-in-head-neck-radiology-state-of-the-art
#1
Gerlig Widmann, Benjamin Henninger, Christian Kremser, Werner Jaschke
Background Magnetic resonance imaging (MRI) has become an essential imaging modality for the evaluation of head & neck pathologies. However, the diagnostic power of MRI is strongly related to the appropriate selection and interpretation of imaging protocols and sequences. The aim of this article is to review state-of-the-art sequences for the clinical routine in head & neck MRI and to describe the evidence for which medical question these sequences and techniques are useful. Method Literature review of state-of-the-art sequences in head & neck MRI...
May 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28413076/detection-of-endolymphatic-hydrops-using-traditional-mr-imaging-sequences
#2
John H Keller, Barry E Hirsch, Ryan S Marovich, Barton F Branstetter
PURPOSE: The purpose of this study was to determine whether Meniere's disease (MD) produces endolymphatic cavity size changes that are detectable using unenhanced high-resolution T2-weighted MRI. MATERIALS & METHODS: This retrospective case-control study included patients with documented MD who had a high-resolution T2-weighted or steady-state free procession MRI of the temporal bones within one month of diagnosis, between 2002 and 2015. Patients were compared to age- and sex- matched controls...
April 6, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28399691/effect-of-aldosterone-on-cochlear-af9-expression-and-hearing-in-guinea-pig
#3
Li Qin, Biyun Zhang, Qianying Wang, Duanchao Li, Xiaoli Luo, Shixun Zhong
CONCLUSIONS: Af9 protein in cochlea may be closely related to endolymph regulation by aldosterone and thus may be involved in pathogenesis of endolymphatic hydrops (EH). OBJECTIVES: EH is the pathological characteristic of Ménière's disease (MD). Aldosterone could induce EH, but its relationship with MD is still controversial. The aim of the present study is to investigate the Af9 protein expression in guinea pig cochlea and regulation of Af9 expression and cochlear function by aldosterone...
April 11, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28382128/endolymphatic-sac-surgery-for-m%C3%A3-ni%C3%A3-re-s-disease-current-opinion-and-literature-review
#4
Maria de Lourdes Flores García, Carolina de la Llata Segura, Juan Carlos Cisneros Lesser, Carlo Pane Pianese
Introduction The endolymphatic sac is thought to maintain the hydrostatic pressure and endolymph homeostasis for the inner ear, and its dysfunction may contribute to the pathophysiology of Ménière's disease. Throughout the years, different surgical procedures for intractable vertigo secondary to Ménière's disease have been described, and though many authors consider these procedures as effective, there are some who question its long-term efficacy and even those who think that vertigo control is achieved more due to a placebo effect than because of the procedure itself...
April 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28374851/claudin-expression-in-the-rat-endolymphatic-duct-and-sac-first-insights-into-regulation-of-the-paracellular-barrier-by-vasopressin
#5
Daniel Runggaldier, Lidia Garcia Pradas, Peter H Neckel, Andreas F Mack, Bernhard Hirt, Corinna Gleiser
Hearing and balance functions of the inner ear rely on the homeostasis of the endolymphatic fluid. When disturbed, pathologic endolymphatic hydrops evolves as observed in Menière's disease. The molecular basis of inner ear fluid regulation across the endolymphatic epithelium is largely unknown. In this study we identified the specific expression of the tight junction (TJ) molecules Claudin 3, 4, 6, 7, 8, 10, and 16 in epithelial preparations of the rat inner ear endolymphatic duct (ED) and endolymphatic sac (ES) by high-throughput qPCR and immunofluorescence confocal microscopy...
April 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28330066/endolymphatic-hydrops-imaging-why-oving-from-semi-quantitative-to-anatomical-based-evaluation
#6
Michael Eliezer, Irène Tropres, Alexandre Krainik, Arnaud Attye
INTRODUCTION: Recently, the semi-quantitative ratio grading for endolymphatic hydrops (EH) was found as none specific of MD because all healthy subjects referred with at least one hydrops location with this grading method and 3D-FLAIR sequence. The objectives of this study were to assess the EH prevalence in MD using both the semi-quantitative ratio method of grading and the Saccule to Utricle Ration Inversion (SURI) technique with two 3D-FLAIR sequences, closely similar except for the inversion time of the sequence...
March 2017: Journal of Neuroradiology. Journal de Neuroradiologie
https://www.readbyqxmd.com/read/28306649/secondary-endolymphatic-hydrops
#7
Ashley P O'Connell Ferster, Sebahattin Cureoglu, Nevra Keskin, Michael M Paparella, Huseyin Isildak
HYPOTHESIS: A review of the most recent literature will provide clinicians with an update of secondary endolymphatic hydrops, aiding in diagnosis and treatment of affected patients. BACKGROUND: Secondary endolymphatic hydrops is a pathologic finding of the inner ear resulting in episodic vertigo and intermittent hearing loss. It is a finding for which extensive research is being performed. METHODS: A review of the most recent literature on secondary endolymphatic hydrops was performed using PubMed literature search...
March 16, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28269598/3d-reconstruction-of-cochlea-using-optical-coherence-tomography
#8
Tuukka Karvonen, Yuki Uranishi, Tatsunori Sakamoto, Yosuke Tona, Kazuya Okamoto, Hiroshi Tamura, Tomohiro Kuroda
Recently, in vivo visualization of the cochlea and the smaller structures inside of it has been achieved by optical coherence tomography (OCT). This makes it possible to use OCT imaging for diagnosis of diseases such as Meniere's disease through measuring the degree of endolymphatic hydrops. To this end, we present a novel method for 3D segmentation of these cochlear OCT images that is based on superpixels and diffusion maps. The method takes as input grayscale volumetric OCT images and outputs a binary image with the segmented cochlea...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28256285/imaging-of-the-endolymphatic-space-in-patients-with-m%C3%A3-ni%C3%A3-re-s-disease
#9
Tadao Yoshida, Satofumi Sugimoto, Masaaki Teranishi, Hironao Otake, Masahiro Yamazaki, Shinji Naganawa, Tsutomu Nakashima, Michihiko Sone
OBJECTIVE: To examine endolymphatic hydrops (EH) using magnetic resonance imaging (MRI) in patients with definite Ménière's disease (MD) and those with nonotological diseases. METHODS: We studied 32 patients with unilateral MD, 10 patients with bilateral MD and 21 patients with control ears who had other benign diseases not associated with hearing or vestibular dysfunction. The mean age of the subjects was 54.0 years (range 27-74) in the MD group and 56.1 years (range 24-79) in the control group...
February 27, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28227854/3d-reconstruction-of-cochlea-using-optical-coherence-tomography
#10
Tuukka Karvonen, Yuki Uranishi, Tatsunori Sakamoto, Yosuke Tona, Kazuya Okamoto, Hiroshi Tamura, Tomohiro Kuroda, Tuukka Karvonen, Yuki Uranishi, Tatsunori Sakamoto, Yosuke Tona, Kazuya Okamoto, Hiroshi Tamura, Tomohiro Kuroda, Yuki Uranishi, Hiroshi Tamura, Tatsunori Sakamoto, Yosuke Tona, Tomohiro Kuroda, Kazuya Okamoto, Tuukka Karvonen
Recently, in vivo visualization of the cochlea and the smaller structures inside of it has been achieved by optical coherence tomography (OCT). This makes it possible to use OCT imaging for diagnosis of diseases such as Meniere's disease through measuring the degree of endolymphatic hydrops. To this end, we present a novel method for 3D segmentation of these cochlear OCT images that is based on superpixels and diffusion maps. The method takes as input grayscale volumetric OCT images and outputs a binary image with the segmented cochlea...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28220492/magnetic-resonance-imaging-of-intratympanic-gadolinium-helps-differentiate-vestibular-migraine-from-m%C3%A3-ni%C3%A3-re-disease
#11
Wenfang Sun, Ping Guo, Tongli Ren, Wuqing Wang
OBJECTIVES/HYPOTHESIS: To study the differential diagnosis of vestibular migraine (VM) and Ménière disease (MD) by using magnetic resonance imaging (MRI) of intratympanic gadolinium. STUDY DESIGN: Prospective cohort study. METHODS: Definite MD patients (n = 30) and definite or probable VM patients (n = 30) were included, and the two groups were age and sex matched. Three-dimensional real inversion recovery (3D-real-IR) MRI was performed 24 hours after bilateral intratympanic gadolinium to assess the presence and degree of endolymphatic hydrops (EH)...
February 21, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28219165/-the-pilot-study-of-type-%C3%A2-allergic-reaction-in-meniere-s-disease-patients
#12
T Pan, Y Zhao, Y J Ding, Z Y Lu, F R Ma
Objective: To evaluate the correlation between type Ⅰ allergic reaction and pathogenesis of Meniere's disease. Methods: A total of 35 (10 male vs. 25 female) patients aged between 21-66 years diagnosed with Meniere's disease were recruited to this study, mean age of them was (47.3±13.6) years. The control group consisted of 15 inpatients (5 male vs. 10 female) with pharyngolaryngeal diseases but without otologic and rhinologic abnormity, mean age was 45.4±12.8 years. Allergic prevalence, serous total immunoglobulin E( tIgE ) levels, serous specific immunoglobulin E( sIgE ) levels and subtypes of T lymphocytes were measured and compared in patients with Meniere's disease and the control group...
February 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28145833/a-new-theory-for-m%C3%A3-ni%C3%A3-re-s-disease
#13
Jeremy Hornibrook, Philip Bird
Ménière's disease is an inner ear disorder characterized by vertigo attacks, fluctuating and progressive hearing loss, tinnitus, and aural fullness in the affected ear. The pathophysiology of Ménière's disease remains elusive. Theories so far are anatomical variation in the size or position of the endolymphatic sac and duct, viral inflammation or autoimmune involvement of the sac, or a genetically determined abnormality of endolymph control. Animal studies on blocking the ductus reuniens and endolymphatic duct have produced hydrops in the cochlea, saccule, and utricle...
February 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28106624/intraoperative-electrocochleography-a-window-into-endolymphatic-hydrops-in-a-patient-with-an-endolymphatic-sac-tumor
#14
William J Riggs, Dominic J Catalano, Michael S Harris, Oliver F Adunka, Aaron C Moberly
OBJECTIVES: Intraoperative electrocochleography (ECochG) provides valuable information regarding inner ear function during surgical procedures. Here, we report findings from ECochG collected at three time intervals during the management of a patient with symptoms of inner ear hydrops. PATIENTS: A 38-year-old man with an endolymphatic sac tumor who demonstrated classic Ménière's symptoms. INTERVENTIONS: Endolymphatic shunt, tumor biopsy, and definitive resection of an endolymphatic sac tumor...
April 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28072657/assessment-of-cochlea-endolymphatic-hydrops-using-3-d-flair-and-3-d-real-ir-sequence-in-guinea-pigs-via-3t-mri-after-intratympanic-gadolinium-a-histopathological-comparison
#15
Feng Wang, Huiying Lyu, Menglong Zhao, Yan Sha, Fang Zhang, Yushu Cheng, Wenhu Huang, Wenlin Tang, Youzhou Xie, Ping Lu
OBJECTIVE: We assessed whether the three-dimensional fluid-attenuated inversion-recovery (3-D FLAIR) and three-dimensional inversion-recovery with real reconstruction (3-D real IR) sequences can be used to detect cochlea endolymphatic hydrops (EHs) in guinea pigs using 3 Tesla magnetic resonance imaging (3T MRI). The results of 3-D real IR imaging were compared with histopathological outcomes. MATERIALS AND METHODS: Fourteen healthy men and women albino guinea pigs were used in this study...
April 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28033296/intratympanic-steroids-injection-is-effective-for-the-treatment-of-drop-attacks-with-m%C3%A3-ni%C3%A3-re-s-disease-and-delayed-endolymphatic-hydrops-a-retrospective-study
#16
Bo Liu, Yangming Leng, Renhong Zhou, Jingjing Liu, Dongdong Liu, Su-Lin Zhang, Wei-Jia Kong
Drop attack (DA) associated with Ménière's disease (MD) and delayed endolymphatic hydrops (DEH) is not common and may cause life-threatening clinical problems. The intratympanic dexamethasone (ITD) is one of primary treatments for MD or DEH. Our study investigated the effect of ITD on the DA associated with endolymphatic hydrops (EH).We retrospectively reviewed 10 patients with MD- and DEH-associated DA between January 2009 and December 2013 in Outpatient Department of Otolaryngology, Union Hospital, Wuhan, China...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28017456/diagnosis-of-endolymphatic-hydrops-by-means-of-3t-magnetic-resonance-imaging-after-intratympanic-administration-of-gadolinium
#17
M Tuñón Gómez, D R Lobo Duro, B Brea Álvarez, J R García-Berrocal
OBJECTIVE: To detect and graduate endolymphatic hydrops or endolymphatic space dilations in patients with suspected Meniere's disease or immune-mediated inner ear disease by magnetic resonance imaging. MATERIAL AND METHODS: A prospective study was performed including all the patients with clinical suspicion of Meniere's disease or immune-mediated inner ear disease treated at the Otolaryngology department during a one year period. In all cases, magnetic resonance imaging (MRI) was performed in a 3T scanner...
December 22, 2016: Radiología
https://www.readbyqxmd.com/read/27999985/mri-of-endolymphatic-hydrops-in-patients-with-meniere-s-disease-a-case-controlled-study-with-a-simplified-classification-based-on-saccular-morphology
#18
Arnaud Attyé, Michael Eliezer, Naïla Boudiaf, Irène Tropres, David Chechin, Sébastien Schmerber, Georges Dumas, Alexandre Krainik
OBJECTIVES: Endolymphatic hydrops (EH) can be studied in patients by MRI. With the semi-quantitative grading system, previous imaging studies showed discrepancies in the occurrence and grading of EH in patients with Meniere's disease (MD). Here, we compared the inversion of the saccule to utricle area ratio (SURI) with the semi-quantitative method of grading conventionally used to diagnose MD. METHODS: Imaging was carried out on a 3-T MRI scanner. We performed 3D-FLAIR sequences 4 h after a single intravenous dose of contrast agent...
December 20, 2016: European Radiology
https://www.readbyqxmd.com/read/27974068/endolymphatic-sac-drainage-for-the-treatment-of-m%C3%A3-ni%C3%A3-re-s-disease
#19
R F Bento, J C Cisneros, A C De Oliveira Fonseca
OBJECTIVE: To describe the results obtained with endolymphatic sac drainage in patients with Ménière's disease. METHOD: A retrospective case review study was conducted of 95 Ménière's disease patients who underwent endolymphatic sac drainage in a tertiary care referral centre, after failing a long course of medical management. The main outcome measures were vertigo control and hearing preservation. RESULTS: In patients with unilateral disease, vertigo control was obtained in 94...
February 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/27942898/assessment-of-endolymphatic-hydrops-and-otolith-function-in-patients-with-m%C3%A3-ni%C3%A3-re-s-disease
#20
Tomoko Okumura, Takao Imai, Yasumitsu Takimoto, Noriaki Takeda, Tadashi Kitahara, Atsuhiko Uno, Takefumi Kamakura, Yasuhiro Osaki, Yoshiyuki Watanabe, Hidenori Inohara
Ménière's disease is associated with hydrops of the inner ear endolymphatic space, and histopathologically, the cochlea and vestibule are usually involved. We used gadolinium-enhanced magnetic resonance imaging and measured cervical and ocular vestibular evoked myogenic potentials and the gain in the utricular induced linear vestibulo-ocular reflex to test the hypothesis that vestibular hydrops in Ménière's disease patients is associated with otolith organ dysfunction. We evaluated 21 patients diagnosed with unilateral definitive Ménière's disease using gadolinium magnetic resonance imaging to detect endolymphatic hydrops in the cochlea and vestibule...
December 10, 2016: European Archives of Oto-rhino-laryngology
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