keyword
https://read.qxmd.com/read/38528943/quantification-of-p-phenylenediamine-in-hair-dyes-and-health-risk-implications-in-the-uae-describing-discordances-between-regulations-and-real-life-practices
#1
JOURNAL ARTICLE
Ammar Abdulrahman Jairoun, Sabaa Saleh Al-Hemyari, Moyad Shahwan, Obaida Jairoun, Sa'ed H Zyoud
BACKGROUND: p-Phenylenediamine (PPD) has been used over the past five decades as a primary precursor in the production of oxidative hair dyes. Numerous health dangers are associated with the short- and long-term use of PPD, raising concerns about its safety. For instance, mounting data suggests that PPD is linked to dermatitis and allergy cases. OBJECTIVE: To quantify the PPD content in hair dyes by measuring the PPD concentration after mixing the ingredients of commercial hair dyes...
2024: Risk Management and Healthcare Policy
https://read.qxmd.com/read/38522571/sweat-protects-against-contact-hypersensitivity-transient-sweat-suppression-compromises-skin-barrier-function-in-mice
#2
JOURNAL ARTICLE
Hironobu Ishimaru, Kenta Nakamoto, Mariko Yamane, Takenobu Yamamoto, Keisuke Kitakaze, Yasuhiro Takenouchi, Kazuhito Tsuboi, Yasuo Okamoto, Yumi Aoyama
Although subtle barrier defects may facilitate allergen penetration, thereby enabling allergic sensitization, the relationship between sweating disturbance and skin barrier function is unknown. However, many studies on contact hypersensitivity in mice examined ear skin, which does not sweat, instead of the footpad, where sweating is uniquely present. Here, we assessed whether sweat suppression in the footpad before hapten application provoked a skin barrier abnormality and reduced inflammatory thresholds to topical haptens...
March 22, 2024: Journal of Investigative Dermatology
https://read.qxmd.com/read/38522555/neutrophil-derived-oxidative-stress-contributes-to-skin-inflammation-and-scratching-in-a-mouse-model-of-allergic-contact-dermatitis-via-triggering-pro-inflammatory-cytokine-and-pruritogen-production-in-skin
#3
JOURNAL ARTICLE
Yunqin Yang, Yushuang Pan, Boyu Liu, Yunwen Zhang, Chengyu Yin, Jie Wang, Huimin Nie, Ruoyao Xu, Yan Tai, Xiaofen He, Xiaomei Shao, Yi Liang, Jianqiao Fang, Boyi Liu
Allergic contact dermatitis (ACD) is a common skin disease featured with skin inflammation and a mixed itch/pain sensation. The itch/pain causes the desire to scratch, affecting both physical and psychological aspects of patients. Nevertheless, the mechanisms underlying itch/pain sensation of ACD still remain elusive. Here, we found that oxidative stress and oxidation-related injury were remarkably increased in the inflamed skin of a mouse model of ACD. Reducing oxidative stress significantly attenuated itch/pain-related scratching, allokonesis and skin inflammation...
March 22, 2024: Biochemical Pharmacology
https://read.qxmd.com/read/38513967/association-between-alopecia-areata-and-allergic-diseases-an-all-of-us-database-study
#4
JOURNAL ARTICLE
Erika Tsutsui, Austin J Piontkowski, Divija Sharma, Nicole Ramsey, Benjamin Ungar
No abstract text is available yet for this article.
March 19, 2024: Annals of Allergy, Asthma & Immunology
https://read.qxmd.com/read/38506867/-patch-test-in-the-diagnosis-of-food-allergy
#5
JOURNAL ARTICLE
Selva Iris Ale
Food allergens are capable of producing adverse reactions through multiple mechanisms of an allergic or non-allergic nature, and through different routes of exposure; generally by ingestion or contact, as in protein contact dermatitis or contact urticaria, including inhalation. Food allergy reactions, in turn, can be mediated by immediate hypersensitivity mechanisms, delayed hypersensitivity or mixed immediate-delayed mechanisms. The reference diagnostic method in food allergy is the double-blind placebo-controlled food challenge test (DBPCFC), but skin and serological tests are important in the clinical context...
December 31, 2023: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://read.qxmd.com/read/38502840/insulin-allergy-presenting-as-protein-contact-dermatitis-letter
#6
JOURNAL ARTICLE
Brittany Ehlert, Kathleen Coerdt, James S Taylor, Fred Hsieh, John S Anthony
No abstract text is available yet for this article.
March 19, 2024: Dermatitis
https://read.qxmd.com/read/38501375/contact-allergy-in-swedish-professional-ice-hockey-players
#7
JOURNAL ARTICLE
Tomas B J Eriksson, Marléne Isaksson, Malin Engfeldt, Jakob Dahlin, Yelverton Tegner, Robert Ofenloch, Magnus Bruze
BACKGROUND: Professional ice hockey players may contract irritant and allergic contact dermatitis. AIMS: To investigate the presence of contact allergy (CA) in professional ice hockey players in Sweden. METHODS: Ten teams from the two top leagues were assessed for potential occupational exposure to sensitizers. Exactly 107 players were patch tested with an extended baseline series and a working series, in total 74 test preparations. The CA rates were compared between the ice hockey players and controls from the general population and dermatitis patients...
March 19, 2024: Contact Dermatitis
https://read.qxmd.com/read/38471795/analysis-of-preservatives-and-fragrances-in-topical-medical-devices-the-need-for-more-stringent-regulation
#8
JOURNAL ARTICLE
Ania Stras, Aleksandra Grassmann, Peter Van Campenhout, Eric Deconinck, Tamara Vanhaecke, Bart Desmedt
INTRODUCTION: Medical devices (MDs) have a long history of use, and come with regulatory frameworks to ensure user safety. Although topically applied MDs in the form of gels and creams might be used on damaged skin, their composition is often similar to that of cosmetic products applicable to intact skin, especially in terms of preservatives and fragrances. However, unlike cosmetics, these products are not subject to compound-specific restrictions when used in MDs. OBJECTIVE: This study aimed to identify and quantify preservatives and fragrances in topically applied MDs and assess their safety towards the Cosmetic Regulation (EC) 1223/2009...
March 12, 2024: Contact Dermatitis
https://read.qxmd.com/read/38469666/first-case-of-protein-contact-dermatitis-after-botulinum-toxin-injection-related-to-a-human-albumin-s-allergy
#9
Pauline Sueur, Fabien Pelletier, Pascal Girardin, Laurianne Moumane, Anne Jeand'Heur, François Aubin, Florence Castelain
No abstract text is available yet for this article.
March 12, 2024: Contact Dermatitis
https://read.qxmd.com/read/38466947/unusual-occupational-eczematous-dermatitis-in-a-fish-tank-cleaner-nitrofurantoin-contact-allergy-unveiled
#10
JOURNAL ARTICLE
Hailey Konisky, Krishna Sharma, Aashka Suvarnakar, Hubert Huho, A Neal Gregory, Albert Huho
No abstract text is available yet for this article.
March 11, 2024: Dermatitis
https://read.qxmd.com/read/38448285/case-report-contact-allergy-to-tapinarof
#11
Andrew Scheman, Eric King, Lilly Kerchinsky, Jack Herbster
No abstract text is available yet for this article.
March 6, 2024: Contact Dermatitis
https://read.qxmd.com/read/38448210/contact-allergy-to-olanzapine-and-saxagliptin-in-a-pharmaceutical-industrial-worker-a-case-report
#12
Huršidić Radulović Azra, Babić Željka, Macan Marija, Macan Jelena
No abstract text is available yet for this article.
March 6, 2024: Contact Dermatitis
https://read.qxmd.com/read/38443083/risk-factors-for-medical-adhesive-related-skin-injury-at-the-site-of-peripherally-inserted-central-venous-catheter-placement-in-patients-with-cancer-a-single-centre-prospective-study-from-china
#13
JOURNAL ARTICLE
Mengying Qi, Yuju Qin, Siya Meng, Nan Feng, Yan Meng
OBJECTIVES: This study aims to explore the incidence of, and risk factors for medical adhesive-related skin injury (MARSI) at peripherally inserted central venous catheter (PICC) sites in patients with cancer. DESIGN: A prospective observational cohort study was conducted at a tertiary hospital in Shenzhen, China. SETTING: This was a single-centre study conducted in a tertiary hospital in Shenzhen, China. PARTICIPANTS: A total of 340 patients with cancer and PICC placement from January 2022 to June 2023 were selected using a convenience sampling method...
March 4, 2024: BMJ Open
https://read.qxmd.com/read/38439720/hypersensitivity-reactions-to-homemade-topical-preparations
#14
JOURNAL ARTICLE
Mislav Rončević, Katarina Radas, Suzana Ljubojević Hadžavdić
Homemade topical preparations are becoming increasingly popular due to the widespread belief that herbal and natural products are a safer and better option in the treatment of various conditions. However, homemade topical preparations can precipitate allergic and irritant reactions, depending on the herbal composition of the preparation. Hypersensitivity reactions to such preparations range from contact allergic dermatitis, contact irritant dermatitis, contact urticaria, toxic reaction, photosensitivity, and phototoxic reaction...
December 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38439631/acquired-aquagenic-syringeal-keratoderma-following-covid-19-infection
#15
JOURNAL ARTICLE
Bryce W Polascik, Samantha P Karklins, Matthew C Johnson, Warren C Hammert, Amy J McMichael
Aquagenic syringeal keratoderma (ASK), rare in males, is characterized by the rapid onset of edematous palmar wrinkling with small white papules after brief contact with water or sweat. A 24-year-old atopic male presented with a 2-week subacute history of bilateral palmar edema with whitish-colored papules after exposure to water, 3 months after having had COVID-19 infection treated with a full course of ritonavir-boosted nirmatrelvir (PAXLOVIDTM ). He had received 3 COVID-19 vaccines (Pfizer, New York, NY) about 12 months prior...
March 4, 2024: Hand: Official Journal of the American Association for Hand Surgery
https://read.qxmd.com/read/38413219/prevalence-of-potential-contact-allergens-in-best-selling-baby-cleansers
#16
JOURNAL ARTICLE
Sasan D Noveir, Jayden Galamgam, Carol E Cheng
Many baby cleansers are promoted as hypoallergic products; however, these claims are not typically validated. This study assessed the 50 best-selling baby cleansers from online retailer Amazon for potential allergens. We found that the presence of most marketing claims, including "hypoallergenic" or "allergy-tested," did not correlate with the number of potential allergens in a cleanser. Furthermore, the total number of marketing claims of a cleanser was positively correlated with the number of allergens, highlighting the discordance between marketing claims and allergen content in baby cleansers...
February 27, 2024: Pediatric Dermatology
https://read.qxmd.com/read/38411217/examining-the-benefits-of-extended-patch-test-series-in-children-a-comprehensive-analysis
#17
JOURNAL ARTICLE
Nicolas Andre, Alisa Usher, Mai Ofri, Vitali Kilimnik, Amir Horev
INTRODUCTION: The growing presence of allergens in materials and scarce data on allergic contact dermatitis in children has increased our need to refine its diagnosis in this population. We aimed to analyze children's specific responsivity to highly reactive subcomponents of Fragrance mix I, Fragrance mix II, and Textile dye mix from the European baseline series. METHODS: We retrospectively analyzed patch test records of children aged 2 to 18 who underwent patch testing with the European baseline series between 2014 and 2022 in Israel...
February 27, 2024: International Journal of Dermatology
https://read.qxmd.com/read/38408437/occupational-contact-allergy-to-black-rubber-antioxidants-in-the-protective-equipment
#18
Annarita Antelmi, Ola Bergendorff
No abstract text is available yet for this article.
February 26, 2024: Contact Dermatitis
https://read.qxmd.com/read/38387040/results-of-patch-testing-with-five-fragrance-materials-hitherto-not-tested-a-dose-finding-study-in-the-clinical-population
#19
JOURNAL ARTICLE
Thanisorn Sukakul, Wolfgang Uter, Margarida Gonçalo, Joseph Huggard, Suzana Ljubojević Hadžavdić, Marie L A Schuttelaar, Cecilia Svedman, Matthias Vey, Marléne Isaksson, Bo Niklasson, Thomas Rustemeyer, Magnus Bruze
BACKGROUND: Quantitative risk assessment (QRA) for skin sensitization is used to derive safe use levels of sensitising fragrance ingredients in products. Post-marketing surveillance of the prevalence of contact allergy to these ingredients provides relevant data to help evaluate the performance of these measures. OBJECTIVES: To determine a suitable patch test concentration for five fragrance materials that had hitherto not been tested on a regular basis. These concentrations are then to be used in a surveillance study with patch testing consecutive patients over an extended monitoring period...
February 22, 2024: Contact Dermatitis
https://read.qxmd.com/read/38386591/allergic-contact-dermatitis-to-linalool-hydroperoxides-pitfalls-in-the-diagnostic-process-findings-from-a-repeated-open-application-test-study
#20
JOURNAL ARTICLE
Thanisorn Sukakul, Magnus Bruze, Martin Mowitz, Anna Kiuru, Cecilia Svedman
<u> Background: </u> Increasing trends of oxidized linalool contact allergy have been reported. However, the impact of reactivity and dose in eliciting allergic contact dermatitis caused by linalool hydroperoxides is insufficiently investigated. <u> Objectives: </u> To perform repeated open application tests (ROATs) using the real-world concentrations of linalool hydroperoxides in patients and control participants. <u> Materials and Methods: </u> Patients who previously had a positive (patients) and a negative (controls) patch test reaction to linalool hydroperoxides 1...
February 21, 2024: Dermatitis
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