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allergy contact dermatitis

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https://www.readbyqxmd.com/read/29029310/fragrance-allergens-linalool-and-limonene-allylic-hydroperoxides-in-skin-allergy-mechanisms-of-action-focusing-on-transcription-factor-nrf2
#1
Chloé Raffalli, Elodie Clouet, Salen Kuresepi, Marie-Hélène Damiens, Jean-Pierre Lepoittevin, Marc Pallardy, Pierre-Jacques Ferret, Elena Giménez-Arnau, Saadia Kerdine-Römer
Allergic contact dermatitis (ACD) is regarded as the most frequent expression of immunotoxicity in humans. Many odorant terpenes commonly used in fragrance compositions are considered as weak skin sensitizers, whereas some of their autoxidation products, allylic hydroperoxides, are classified as strong sensitizers according to the Local Lymph Node Assay (LLNA). However, the mechanism of their effects on the immune system remains unclear. Since dendritic cells play a key role in ACD, we studied their activation by the frequently used linalool (LINA) and limonene (LIMO), and their respective sensitizing allylic hydroperoxides (LINA-OOH, LIMO-OOH)...
September 29, 2017: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28969846/prospective-single-center-observational-study-of-the-allergenic-potential-of-mercromina-film-and-other-common-antiseptics-in-patients-with-contact-dermatitis
#2
S Baltà Cruz, N Moreno Ribera, M T Estrach Panella
INTRODUCTION: Although Mercromina Film and other topical antiseptics are widely used, they are not included in the standard series recommended by the Spanish Contact Dermatitis and Skin Allergy Research Group for testing suspected allergic contact dermatitis (ACD). Furthermore, no recent studies have investigated the allergenic potential of merbromin. OBJECTIVE: To determine the allergenic potential of merbromin and compare it with that of other topical antiseptics widely used in clinical practice, including povidone-iodine, chlorhexidine, and eosin...
September 29, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28969253/patch-test-results-from-an-occupational-and-contact-dermatitis-clinic-in-a-tertiary-care-hospital-of-southern-india-a-retrospective-study
#3
Kumaravel Sadagopan, Deepa Kalappan, Nirmala Sivaprakasam, Vinoth
INTRODUCTION: Occupational contact dermatitis, accounting for 95% of cases of occupational dermatoses, is the most common occupational skin disease. AIM: To find out the various allergens in different occupational and environmental settings causing contact allergy, from our patients presented with contact dermatitis. MATERIALS AND METHODS: It was a retrospective study from the data in hospital outpatient register over one year period, which includes patients with age ranging from 11 years to 73 years...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28961293/wearable-health-device-dermatitis-a-case-of-acrylate-related-contact-allergy
#4
Flaura K Winston, Albert C Yan
The popularity of mobile wearable health devices has skyrocketed. Some of these devices are worn on the wrist and have been associated with the development of allergic contact dermatitis. Although nickel has been the suspected culprit in cases reported by the media for consumers, we present a rare report of a patient who developed a localized contact dermatitis that was linked to acrylate allergy on epicutaneous patch testing. We surmise that the source of this acrylate might derive from leaching of this compound from the rechargeable battery housing given its correspondence to where the rash arose...
August 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28951705/the-role-of-nickel-allergy-in-hand-dermatitis-and-its-impact-on-handling-cupronickel-currency-coins-a-comparative-cohort-study-from-kuwait
#5
Nawaf Almutairi, Fahad Almutawa
INTRODUCTION: Contact with nickel-releasing coins as a cause of hand dermatitis has been debated. AIM: Studying a hand dermatitis risk from handling Kuwaiti cupronickel coins among nickel-allergic and nickel non-allergic subjects. MATERIAL AND METHODS: One hundred hand dermatitis patients (group I: nickel-allergic) and 100 matched patients (group II: nickel non-allergic) were selected from over 500 hand dermatitis cases seen between September 2014 and September 2015...
August 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28940507/contact-dermatitis-caused-by-tulips-identification-of-contact-sensitizers-in-tulip-workers-of-kashmir-valley-in-north-india
#6
Iffat Hassan, Farhan Rasool, Saniya Akhtar, Afifa Kamili, Parvaiz Rather, Raihana Kanth, Yasmeen Bhat, Shagufta Rather, Syed Mubashir, Atiya Yaseen, Safia Bashir
BACKGROUND: Tulip, belonging to the genus Tulipa and family Liliaceae, is a spring-blooming perennial that grows from bulbs. Owing to manual handling, contact dermatitis can occur in professionals at any stage of the growth cycle of the tulip plant. OBJECTIVES: To determine the clinical pattern of contact dermatitis resulting from tulip plant cultivation, and to assess contact allergy in workers coming into contact with this plant. METHODS: One hundred and sixty-four tulip workers were screened, and 48 patients with suspected contact dermatitis were patch tested with 39 allergens, including haptens from the Indian baseline series, a plant series, and extracts from different parts of the tulip plant...
September 21, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28940210/contact-allergy-to-lanolin-temporal-changes-in-prevalence-and-association-with-atopic-dermatitis
#7
Marloes Fransen, Line E K Overgaard, Jeanne D Johansen, Jacob P Thyssen
BACKGROUND: Lanolin has been tested as lanolin alcohols (30% pet.) in baseline patch test series since 1969, and this has shown clinically relevant allergic contact dermatitis cases. OBJECTIVES: To investigate the temporal development of lanolin allergy (i.e. positive reaction to lanolin alcohols and/or Amerchol™ L-101), and the association between contact allergy to lanolin and patient characteristics from the MOAHLFA index. METHODS: A retrospective observational study of consecutively patch tested dermatitis patients (n = 9577) between 1 January 2004 and 31 December 2015 with lanolin alcohols 30% pet...
September 21, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28895957/atopic-dermatitis-addressing-allergy-infection-itch-and-complementary-therapies
#8
Jusleen Ahluwalia, Dawn Marie Davis, Sharon Jacob, Andrea Waldman, Peter Y Ong, Stuart Cohen, Adam Friedman, Peter Lio, Nathan Jetter, Jeffrey Bienstock, Jennifer LeBovidge, Jonathan Spergel, Luz Fonacier
Atopic dermatitis (AD) is a complex condition that results from the dynamic interplay between genetic predisposition, skin barrier defects, environmental factors, and a dysfunctional immune system. As a result, AD can be complicated by irritant and allergic contact dermatitis and imbalances in the skin microbiome, which can subsequently exacerbate the severity and complicate the course of preexisting atopic disease. Itch is an important symptom of AD, as it plays a large role in the quality of life of patients and their families...
September 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28889150/screening-for-skin-sensitizing-allergens-among-patients-with-clinically-suspected-allergic-contact-dermatitis
#9
Zahid Shakoor, Ahlam S Al-Mutairi, Afnan M Al-Shenaifi, Areej M Al-Abdulsalam, Bashayer Z Al-Shirah, Shahad A Al-Harbi
To detect common skin-sensitizing agents among patients experiencing allergic contact dermatitis (ACD). Methods: This was a retrospective study of 152 patients with clinically suspected ACD who underwent patch testing in an allergy clinic at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between January 2012 and February 2015. Of these patients, only 74 (48%) patients reacted to one or more contact allergens. This group of patients included 58 (78.4%) women and 16 (21.6%) men (mean age: 37...
September 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28871922/development-and-significance-of-the-e-surveillance-system-for-contact-allergies-in-slovenia
#10
Aleksandra Dugonik, Maja Kalač Pandurovič, Marko Vok, Bogdan Dugonik
This paper describes the development and significance of online systems for the collection and analysis of medical data (patch test results) with a web application. Modern digital tools greatly aid in collecting, combining, and preserving the data in a way that is friendly, undemanding and time-efficient for the dermatologist. Creating a central database for the results of patch testing provides a better picture of contact sensitivity and characteristics of allergic contact dermatitis in Slovenia. An electronic database and connected network was started in Slovenia in 2010...
July 2017: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28776709/allergic-contact-dermatitis-caused-by-dimethylthiocarbamylbenzothiazole-sulfide-dmtbs-in-canvas-shoes-in-search-of-the-culprit-allergen
#11
Marie L Schuttelaar, Joost M Meijer, Malin Engfeldt, Hilde Lapeere, An Goossens, Magnus Bruze, Christina Persson, Ola Bergendorff
BACKGROUND: During rubber vulcanization, new compounds can be formed. OBJECTIVES: To report a case of allergic shoe dermatitis in which the search for the allergen ultimately led to the identification of dimethylthiocarbamylbenzothiazole sulfide (DMTBS). METHODS: A female presented with eczema on her feet after wearing Sperry Top Sider® canvas sneakers. Patch testing was performed with the European baseline series, additional series, shoe materials, and extracts of shoe materials...
August 4, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28748553/accelerator-free-gloves-as-alternatives-in-cases-of-glove-allergy-in-healthcare-workers
#12
Marie-Noëlle Crepy, Jérome Lecuen, Carole Ratour-Bigot, Jill Stocks, Lynda Bensefa-Colas
BACKGROUND: Accelerators in rubber gloves constitute an important group of contact allergens, particularly in healthcare workers. OBJECTIVES: To assess the efficacy of accelerator-free medical gloves in the secondary prevention of allergic contact dermatitis caused by rubber accelerators in healthcare workers. METHODS: Nine healthcare workers with hand eczema were advised to use accelerator-free rubber gloves after a diagnosis of allergic contact dermatitis caused by rubber accelerators...
July 27, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28732699/triggers-of-oral-lichen-planus-flares-and-the-potential-role-of-trigger-avoidance-in-disease-management
#13
Hannah X Chen, Rachel Blasiak, Edwin Kim, Ricardo Padilla, Donna A Culton
OBJECTIVE: Many patients with oral lichen planus (OLP) report triggers of flares, some of which overlap with triggers of other oral diseases, including oral allergy syndrome and oral contact dermatitis. The purpose of this study was to evaluate the prevalence of commonly reported triggers of OLP flares, their overlap with triggers of other oral diseases, and the potential role of trigger avoidance as a management strategy. STUDY DESIGN: Questionnaire-based survey of 51 patients with biopsy-proven lichen planus with oral involvement seen in an academic dermatology specialty clinic and/or oral pathology clinic between June 2014 and June 2015...
May 30, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28730624/prevalence-of-nickel-allergy-in-europe-following-the-eu-nickel-directive%C3%A2-%C3%A2-a-review
#14
REVIEW
Malin G Ahlström, Jacob P Thyssen, Torkil Menné, Jeanne D Johansen
Nickel contact allergy remains a problem in EU countries, despite the EU Nickel Directive. To study the prevalence of nickel allergy in EU countries following the implementation of the EU Nickel Directive, we performed a systematic search in PubMed for studies that examined the prevalence of nickel allergy in EU countries published during 2005-2016. We identified 46 studies: 10 in the general population and 36 in patch tested dermatitis patients. A significantly lower prevalence of nickel allergy after than before the implementation of the EU Nickel Directive was found in women aged 18-35 years (11...
July 21, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28719475/allergic-contact-dermatitis-from-methylisothiazolinone-in-residential-wall-paint
#15
Molly C Goodier, Linda Ljungberg, Christina Persson, Malin Engfeldt, Magnus Bruze, Erin M Warshaw
A 33-year-old woman presented to our clinic for suspected photoallergic contact dermatitis with a recent episode of severe, vesicular dermatitis involving exposed skin and correlating with relocation to a new home. Biopsy results showed spongiotic and lichenoid dermatitis with eosinophils. Patch test results showed a very strong (+++) reaction to methylisothiazolinone (MI), mild (+) reaction to MI/methylchloroisothiazolinone, and no reaction to benzisothiazolinone. These allergens were found in several personal products...
July 2017: Dermatitis
https://www.readbyqxmd.com/read/28675503/a-population-based-study-of-self-reported-skin-exposures-and-symptoms-in-relation-to-contact-allergy-in-adolescents
#16
Maria Lagrelius, Carl-Fredrik Wahlgren, Mihály Matura, Anna Bergström, Inger Kull, Carola Lidén
BACKGROUND: Knowledge about the relations between skin exposures, skin symptoms and contact allergy in adolescents is limited. OBJECTIVES: To explore self-reported skin exposures and skin symptoms in girls and boys, and to assess the associations between exposures, symptoms and contact allergy at age 16 years. PARTICIPANTS AND METHODS: In all, 3115 adolescents from the population-based BAMSE birth cohort answered a questionnaire at age 16 concerning various skin exposures and related skin symptoms...
July 4, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28672829/fexofenadine-suppresses-delayed-type-hypersensitivity-in-the-murine-model-of-palladium-allergy
#17
Ryota Matsubara, Kenichi Kumagai, Hiroaki Shigematsu, Kazutaka Kitaura, Yasunari Nakasone, Satsuki Suzuki, Yoshiki Hamada, Ryuji Suzuki
Palladium is frequently used in dental materials, and sometimes causes metal allergy. It has been suggested that the immune response by palladium-specific T cells may be responsible for the pathogenesis of delayed-type hypersensitivity in study of palladium allergic model mice. In the clinical setting, glucocorticoids and antihistamine drugs are commonly used for treatment of contact dermatitis. However, the precise mechanism of immune suppression in palladium allergy remains unknown. We investigated inhibition of the immune response in palladium allergic mice by administration of prednisolone as a glucocorticoid and fexofenadine hydrochloride as an antihistamine...
June 25, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28670256/contact-allergy-in-the-population-of-patients-with-chronic-inflammatory-dermatoses-and-contact-hypersensitivity-to-corticosteroids
#18
Marek Kot, Jarosław Bogaczewicz, Beata Kręcisz, Anna Woźniacka
INTRODUCTION: Clinical studies indicate that contact allergy to glucocorticosteroids (GCS) is not rare and has been increasingly reported over the past decade. Among the risk factors for developing contact hypersensitivity to topical corticosteroids, chronic inflammatory skin diseases and polyvalent contact allergy seem to be most important. AIM: To present the structure of contact allergy in the population of patients with chronic inflammatory dermatoses (CID) and contact hypersensitivity to corticosteroids...
June 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28670248/allergic-contact-dermatitis-pattern-in-kuwait-nickel-leads-the-pack-in-depth-analysis-of-nickel-allergy-based-on-the-results-from-a-large-prospective-patch-test-series-report
#19
Nawaf Almutairi, Fahad Almutawa
INTRODUCTION: Contact dermatitis is a relatively common dermatosis reported among several population groups from all around the globe. However, the data from Kuwait is unavailable. Patch tests are essential for the diagnosis of contact sensitization. AIM: To determine a relative frequency and pattern of sensitizers to different allergens in patients of suspected contact dermatitis in Kuwait and, also to study the role of the commonest sensitizer in detail. MATERIAL AND METHODS: Patch tests were performed in 2461 consecutive patients with a clinical diagnosis of contact dermatitis seen at our hospital between September 1, 2014 and August 31, 2015...
June 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28653246/allergy-and-sexual-behaviours-an-update
#20
REVIEW
Marco Caminati, Veronica Giorgis, Boaz Palterer, Francesca Racca, Chiara Salvottini, Oliviero Rossi
The exact prevalence of hypersensitivity reactions related to sexual behaviours is not known; however, they heavily impact on the quality of life and of sex life of affected patients. In fact, not only common respiratory and skin allergies, such as asthma, rhinitis, urticaria and atopic dermatitis, but also food and drug allergy have been found to negatively affect the quality of sex life. Allergic diseases impact on the sexual function in both physical and psychological ways, representing one of the main complaints of a considerable proportion of patients...
June 26, 2017: Clinical Reviews in Allergy & Immunology
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