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allergy contact dermatitis

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https://www.readbyqxmd.com/read/28776709/allergic-contact-dermatitis-caused-by-dimethylthiocarbamylbenzothiazole-sulfide-dmtbs-in-canvas-shoes-in-search-of-the-culprit-allergen
#1
Marie L Schuttelaar, Joost M Meijer, Malin Engfeldt, Hilde Lapeere, An Goossens, Magnus Bruze, Christina Persson, Ola Bergendorff
BACKGROUND: During rubber vulcanization, new compounds can be formed. OBJECTIVES: To report a case of allergic shoe dermatitis in which the search for the allergen ultimately led to the identification of dimethylthiocarbamylbenzothiazole sulfide (DMTBS). METHODS: A female presented with eczema on her feet after wearing Sperry Top Sider® canvas sneakers. Patch testing was performed with the European baseline series, additional series, shoe materials, and extracts of shoe materials...
August 4, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28748553/accelerator-free-gloves-as-alternatives-in-cases-of-glove-allergy-in-healthcare-workers
#2
Marie-Noëlle Crepy, Jérome Lecuen, Carole Ratour-Bigot, Jill Stocks, Lynda Bensefa-Colas
BACKGROUND: Accelerators in rubber gloves constitute an important group of contact allergens, particularly in healthcare workers. OBJECTIVES: To assess the efficacy of accelerator-free medical gloves in the secondary prevention of allergic contact dermatitis caused by rubber accelerators in healthcare workers. METHODS: Nine healthcare workers with hand eczema were advised to use accelerator-free rubber gloves after a diagnosis of allergic contact dermatitis caused by rubber accelerators...
July 27, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28732699/triggers-of-oral-lichen-planus-flares-and-the-potential-role-of-trigger-avoidance-in-disease-management
#3
Hannah X Chen, Rachel Blasiak, Edwin Kim, Ricardo Padilla, Donna A Culton
OBJECTIVE: Many patients with oral lichen planus (OLP) report triggers of flares, some of which overlap with triggers of other oral diseases, including oral allergy syndrome and oral contact dermatitis. The purpose of this study was to evaluate the prevalence of commonly reported triggers of OLP flares, their overlap with triggers of other oral diseases, and the potential role of trigger avoidance as a management strategy. STUDY DESIGN: Questionnaire-based survey of 51 patients with biopsy-proven lichen planus with oral involvement seen in an academic dermatology specialty clinic and/or oral pathology clinic between June 2014 and June 2015...
May 30, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28730624/prevalence-of-nickel-allergy-in-europe-following-the-eu-nickel-directive%C3%A2-%C3%A2-a-review
#4
REVIEW
Malin G Ahlström, Jacob P Thyssen, Torkil Menné, Jeanne D Johansen
Nickel contact allergy remains a problem in EU countries, despite the EU Nickel Directive. To study the prevalence of nickel allergy in EU countries following the implementation of the EU Nickel Directive, we performed a systematic search in PubMed for studies that examined the prevalence of nickel allergy in EU countries published during 2005-2016. We identified 46 studies: 10 in the general population and 36 in patch tested dermatitis patients. A significantly lower prevalence of nickel allergy after than before the implementation of the EU Nickel Directive was found in women aged 18-35 years (11...
July 21, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28719475/allergic-contact-dermatitis-from-methylisothiazolinone-in-residential-wall-paint
#5
Molly C Goodier, Linda Ljungberg, Christina Persson, Malin Engfeldt, Magnus Bruze, Erin M Warshaw
A 33-year-old woman presented to our clinic for suspected photoallergic contact dermatitis with a recent episode of severe, vesicular dermatitis involving exposed skin and correlating with relocation to a new home. Biopsy results showed spongiotic and lichenoid dermatitis with eosinophils. Patch test results showed a very strong (+++) reaction to methylisothiazolinone (MI), mild (+) reaction to MI/methylchloroisothiazolinone, and no reaction to benzisothiazolinone. These allergens were found in several personal products...
July 2017: Dermatitis
https://www.readbyqxmd.com/read/28675503/a-population-based-study-of-self-reported-skin-exposures-and-symptoms-in-relation-to-contact-allergy-in-adolescents
#6
Maria Lagrelius, Carl-Fredrik Wahlgren, Mihály Matura, Anna Bergström, Inger Kull, Carola Lidén
BACKGROUND: Knowledge about the relations between skin exposures, skin symptoms and contact allergy in adolescents is limited. OBJECTIVES: To explore self-reported skin exposures and skin symptoms in girls and boys, and to assess the associations between exposures, symptoms and contact allergy at age 16 years. PARTICIPANTS AND METHODS: In all, 3115 adolescents from the population-based BAMSE birth cohort answered a questionnaire at age 16 concerning various skin exposures and related skin symptoms...
July 4, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28672829/fexofenadine-suppresses-delayed-type-hypersensitivity-in-the-murine-model-of-palladium-allergy
#7
Ryota Matsubara, Kenichi Kumagai, Hiroaki Shigematsu, Kazutaka Kitaura, Yasunari Nakasone, Satsuki Suzuki, Yoshiki Hamada, Ryuji Suzuki
Palladium is frequently used in dental materials, and sometimes causes metal allergy. It has been suggested that the immune response by palladium-specific T cells may be responsible for the pathogenesis of delayed-type hypersensitivity in study of palladium allergic model mice. In the clinical setting, glucocorticoids and antihistamine drugs are commonly used for treatment of contact dermatitis. However, the precise mechanism of immune suppression in palladium allergy remains unknown. We investigated inhibition of the immune response in palladium allergic mice by administration of prednisolone as a glucocorticoid and fexofenadine hydrochloride as an antihistamine...
June 25, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28670256/contact-allergy-in-the-population-of-patients-with-chronic-inflammatory-dermatoses-and-contact-hypersensitivity-to-corticosteroids
#8
Marek Kot, Jarosław Bogaczewicz, Beata Kręcisz, Anna Woźniacka
INTRODUCTION: Clinical studies indicate that contact allergy to glucocorticosteroids (GCS) is not rare and has been increasingly reported over the past decade. Among the risk factors for developing contact hypersensitivity to topical corticosteroids, chronic inflammatory skin diseases and polyvalent contact allergy seem to be most important. AIM: To present the structure of contact allergy in the population of patients with chronic inflammatory dermatoses (CID) and contact hypersensitivity to corticosteroids...
June 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28670248/allergic-contact-dermatitis-pattern-in-kuwait-nickel-leads-the-pack-in-depth-analysis-of-nickel-allergy-based-on-the-results-from-a-large-prospective-patch-test-series-report
#9
Nawaf Almutairi, Fahad Almutawa
INTRODUCTION: Contact dermatitis is a relatively common dermatosis reported among several population groups from all around the globe. However, the data from Kuwait is unavailable. Patch tests are essential for the diagnosis of contact sensitization. AIM: To determine a relative frequency and pattern of sensitizers to different allergens in patients of suspected contact dermatitis in Kuwait and, also to study the role of the commonest sensitizer in detail. MATERIAL AND METHODS: Patch tests were performed in 2461 consecutive patients with a clinical diagnosis of contact dermatitis seen at our hospital between September 1, 2014 and August 31, 2015...
June 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28653246/allergy-and-sexual-behaviours-an-update
#10
REVIEW
Marco Caminati, Veronica Giorgis, Boaz Palterer, Francesca Racca, Chiara Salvottini, Oliviero Rossi
The exact prevalence of hypersensitivity reactions related to sexual behaviours is not known; however, they heavily impact on the quality of life and of sex life of affected patients. In fact, not only common respiratory and skin allergies, such as asthma, rhinitis, urticaria and atopic dermatitis, but also food and drug allergy have been found to negatively affect the quality of sex life. Allergic diseases impact on the sexual function in both physical and psychological ways, representing one of the main complaints of a considerable proportion of patients...
June 26, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28638049/immunomodulatory-effects-of-nanoparticles-on-skin-allergy
#11
Samreen Jatana, Brian C Palmer, Sarah J Phelan, Lisa A DeLouise
In recent years there has been considerable effort to understand the interaction of nanomaterials with the skin. In this study we use an in vivo mouse model of allergic contact dermatitis to investigate how nanoparticles (NPs) may alter allergic responses in skin. We investigate a variety of NPs that vary in size, charge and composition. Results show that small (<200 nm) negative and neutral charged NPs exhibit an immunosuppressive effect but that positively charged NPs do not. Confocal imaging suggests positively charged NPs may penetrate skin to a lesser extent and thereby are less able interact with and alter the local immune responses...
June 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28627111/european-surveillance-system-on-contact-allergies-essca-results-with-the-european-baseline-series-2013-14
#12
W Uter, J C Amario-Hita, A Balato, B Ballmer-Weber, A Bauer, A Belloni Fortina, A Bircher, M M U Chowdhury, S M Cooper, A Dugonik, R Gallo, A Giménez-Arnau, J D Johansen, S M John, M Kieć-Świerczyńska, T Kmecl, B Kręcisz, F Larese Filon, V Mahler, M Pesonen, T Rustemeyer, A Sadowska-Przytocka, J Sánchez-Perez, S Schliemann, M L Schuttelaar, D Simon, R Spiewak, S Valiukeviciene, E Weisshaar, I R White, S M Wilkinson
BACKGROUND: Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, a consequence of introduction of new substances, new products or formulations, and regulatory intervention, the spectrum of contact sensitisation changes. OBJECTIVE: To evaluate the current spectrum of contact allergy to allergens present in the European baseline series (EBS) across Europe. METHODS: Retrospective analysis of data collected by the European Surveillance System on Contact Allergies (ESSCA, www...
June 19, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28608297/neomycin-polymyxin-b-and-dexamethasone-allergic-reactions-following-periocular-surgery
#13
Nicholas A Moore, Craig N Czyz, Tracy D Carter, Jill A Foster, Kenneth V Cahill
BACKGROUND: The aim of this study was to evaluate the rate of periocular allergic skin reactions to topical neomycin, polymyxin B, and dexamethasone (NPD) ophthalmic ointment. METHODS: A consecutive patient prospective study was performed. A total of 522 patients who had a procedure involving incision of the periocular skin with subsequent postoperative application of NPD ophthalmic ointment were included. Patients were evaluated for signs of allergy at 1 week postoperatively or prior if the patient had complaints...
December 2017: Journal of Ophthalmic Inflammation and Infection
https://www.readbyqxmd.com/read/28568892/patch-testing-in-patients-with-suspected-cosmetic-dermatitis-a-retrospective-study
#14
Taru Garg, Soumya Agarwal, Ram Chander, Aashim Singh, Pravesh Yadav
BACKGROUND: Growing use of cosmetics has led to an increase in the incidence of allergic contact dermatitis (ACD) to cosmetics. Patch testing helps to confirm allergy to cosmetics and pinpoint the exact offending allergens. AIMS AND OBJECTIVES: The study aimed to find the frequency of positive patch test reactions in cases with suspected ACD to cosmetics, and the common allergens responsible for it. METHODS: This is a retrospective record-based study of 58 patients, with suspected ACD to cosmetics, who had undergone patch testing with Indian standard series and Indian cosmetic and fragrance series from January 2013 to December 2015...
June 1, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28554661/using-dr52c-ni-2-mimotope-tetramers-to-detect-ni-2-reactive-cd4-t-cells-in-patients-with-joint-replacement-failure
#15
Yan Zhang, Yang Wang, Kirsten Anderson, Andrey Novikov, Zikou Liu, Karin Pacheco, Shaodong Dai
T cell mediated hypersensitivity to nickel (Ni(2+)) is one of the most common causes of allergic contact dermatitis. Ni(2+) sensitization may also contribute to the failure of Ni(2+) containing joint implants, and revision to non-Ni(2+) containing hardware can be costly and debilitating. Previously, we identified Ni(2+) mimotope peptides, which are reactive to a CD4(+) T cell clone, ANi2.3 (Vα1, Vβ17), isolated from a Ni(2+) hypersensitive patient with contact dermatitis. This T cell is restricted to the major histocompatibility complex class II (MHCII) molecule, Human Leukocyte Antigen (HLA)-DR52c (DRA, DRB3*0301)...
May 26, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28548971/allergic-contact-dermatitis-in-preservatives-current-standing-and-future-options
#16
Gustavo Deza, Ana M Giménez-Arnau
PURPOSE OF REVIEW: Preservatives are well known skin sensitizers and represent one of the main causes of contact allergy. The purpose of this article is to review the current state of contact sensitization induced by preservatives and point future alternatives for products' preservation. RECENT FINDINGS: Isothiazolinones currently are the most common preservatives responsible of contact allergy in Europe and in the United States, and although some regulatory interventions have been taken place, the current contact allergy outbreak is not yet under control...
August 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28538006/evaluation-and-management-of-patch-test-negative-patients-with-generalized-dermatitis
#17
Alison Spiker, Christen M Mowad
BACKGROUND: Patients with generalized dermatitis are common in dermatology practices. Allergic contact dermatitis is often suspected, and patients frequently undergo patch testing. When the patch testing result is negative, further evaluation and management of these patients are challenging. OBJECTIVE: The purpose of this study was to survey members of the American Contact Dermatitis Society regarding the evaluation and management of patch test-negative patients with generalized dermatitis...
July 2017: Dermatitis
https://www.readbyqxmd.com/read/28530059/-chronic-dermatitis-of-the-dorsum-of-the-feet-and-shins-due-to-allergic-contact-dermatitis-to-leather-products
#18
Liran Horev
A 40 year old woman presented with dermatitis mainly involving her dorsal feet and shins, a condition which was present for a prolonged period of time. The distribution was suggestive of allergic contact dermatitis, possibly to her shoes. Patch tests disclosed allergy to chromates, cobalt, colophony, all present in leather products, and allergy to myroxylon pereirae (Balsam of Peru). The patient was instructed to avoid wearing some of her shoes and sitting on her leather sofa. As a consequence, her symptoms ameliorated...
October 2016: Harefuah
https://www.readbyqxmd.com/read/28524256/quantification-of-l-carvone-in-toothpastes-available-on-the-swedish-market
#19
Liv Kroona, Gunnar Warfvinge, Marléne Isaksson, Camilla Ahlgren, Jakob Dahlin, Östen Sörensen, Magnus Bruze
BACKGROUND: Toothpastes have widespread use in the population, and contain flavours used to give a pleasant and often minty aroma. Flavours are prevalent allergens in toothpastes, and adverse reactions often present as perioral dermatitis or stomatitis. l-Carvone, a mint flavour found in spearmint oil, is one of these allergens. There are few studies on contact allergy to l-carvone, and some of them have indicated a positive relationship with oral lichenoid lesions. OBJECTIVES: To qualitatively and quantitatively investigate the presence of l-carvone in commercially available toothpastes on the Swedish market...
May 19, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28523864/allergic-contact-dermatitis-due-to-methylisothiazolinone-in-a-young-girl-s-laundry-detergent
#20
Colleen H Cotton, Cliff G Duah, Catalina Matiz
Methylisothiazolinone (MI) is an emerging and increasing cause of allergic contact dermatitis (ACD) in children. We present the case of a 7-year-old girl with an unusual dermatitis suspicious for contact allergy. Patch testing confirmed allergy to MI, found only in the patient's laundry detergent. This case highlights the importance of checking household product ingredients and the role of MI as an increasing cause of ACD in children.
May 19, 2017: Pediatric Dermatology
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