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https://www.readbyqxmd.com/read/28221146/-new-strategies-and-protocols-in-swl
#1
Alberto Budía Alba, Pilar Bahilo Mateu, Guzmán Ordaz Jurado, José Daniel López-Acón, Marta Trassierra Villa, Francisco Boronat Tormo
OBJECTIVE: An update of the new treatment strategies in extracorporeal lithotripsy as a valid therapeutic alternative in the management of urinary calculi. METHODS: We performed a search and review of the most recent literature which responded to the terms "best practices", "update", "optimization", "practice pattern" in lithotripsy. Only articles written in English or Spanish were selected. RESULTS: The use of a stepwise voltage ramping during extracorporeal lithotripsy with or without pause before the first rise of energy, a decreased delivery rates and the use of a higher number of shock waves per session are shown as alternatives to improve the effectiveness with optimum safety profile...
January 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28213854/bilateral-simultaneous-ureteroscopic-bs-urs-approach-in-the-management-of-bilateral-urolithiasis-is-a-safe-and-effective-strategy-in-the-contemporary-era-evidence-from-a-systematic-review
#2
REVIEW
Robert M Geraghty, Bhavan P Rai, Patrick Jones, Bhaskar K Somani
PURPOSE OF REVIEW: Ureteroscopic treatment of urolithiasis has become safer and more effective in the modern era. With a rise in the incidence of bilateral urolithiasis, management dilemma of staged single-side ureteroscopy versus bilateral simultaneous ureteroscopy (BS-URS) is often debatable. This review evaluates the current evidence base for bilateral simultaneous ureteroscopic approach in the modern era. RECENT FINDINGS: A systematic review was conducted from 1990 to June 2016 including all English language articles reporting on outcomes of BS-URS for urolithiasis...
February 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28181139/cytoprotective-and-anti-apoptotic-role-of-terminalia-arjuna-on-oxalate-injured-renal-epithelial-cells
#3
Amisha Mittal, Simran Tandon, Surender Kumar Singla, Chanderdeep Tandon
Urolithiasis is one of the painful multifactorial disorders caused by metabolic abnormalities influencing the composition of body fluids and urine. The bark of Terminalia arjuna (T. arjuna), very well known in Ayurveda for the treatment of cardiovascular diseases, possesses antioxidant and diuretic activity. The present study was undertaken to investigate the antiurolithiatic efficacy of aqueous extract of bark of T. arjuna on oxalate-induced injury to renal tubular epithelial cells. Madin-Darby canine kidney (MDCK) cells were exposed to 2 mM oxalate for 48 h to evaluate the protective effect of T...
February 8, 2017: Cytotechnology
https://www.readbyqxmd.com/read/28165480/%C3%AE-lipoic-acid-treatment-prevents-cystine-urolithiasis-in-a-mouse-model-of-cystinuria
#4
Tiffany Zee, Neelanjan Bose, Jarcy Zee, Jennifer N Beck, See Yang, Jaspreet Parihar, Min Yang, Sruthi Damodar, David Hall, Monique N O'Leary, Arvind Ramanathan, Roy R Gerona, David W Killilea, Thomas Chi, Jay Tischfield, Amrik Sahota, Arnold Kahn, Marshall L Stoller, Pankaj Kapahi
Cystinuria is an incompletely dominant disorder characterized by defective urinary cystine reabsorption that results in the formation of cystine-based urinary stones. Current treatment options are limited in their effectiveness at preventing stone recurrence and are often poorly tolerated. We report that the nutritional supplement α-lipoic acid inhibits cystine stone formation in the Slc3a1(-/-) mouse model of cystinuria by increasing the solubility of urinary cystine. These findings identify a novel therapeutic strategy for the clinical treatment of cystinuria...
February 6, 2017: Nature Medicine
https://www.readbyqxmd.com/read/28125004/antioxidant-pre-treatment-reduces-the-toxic-effects-of-oxalate-on-renal-epithelial-cells-in-a-cell-culture-model-of-urolithiasis
#5
Tomislav Kizivat, Martina Smolić, Ivana Marić, Maja Tolušić Levak, Robert Smolić, Ines Bilić Čurčić, Lucija Kuna, Ivan Mihaljević, Aleksandar Včev, Sandra Tucak-Zorić
Urolithiasis is characterized by the formation and retention of solid crystals within the urinary tract. Kidney stones are mostly composed of calcium oxalate, which predominantly generates free radicals that are toxic to renal tubular cells. The aim of the study is to explore possible effects of antioxidant pre-treatment on inhibition of oxidative stress. Three cell lines were used as in vitro model of urolithiasis: MDCK I, MDCK II and LLC-PK1. Oxidative stress was induced by exposure of cells to sodium oxalate in concentration of 8 mM...
January 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28124521/forming-a-stone-in-pelviureteric-junction-obstruction-cause-or-effect
#6
Theodora Stasinou, Andreas Bourdoumis, Junaid Masood
OBJECTIVES: To investigate a possible causal relationship for stone formation in pelviureteric junction obstruction and to outline management options. MATERIALS AND METHODS: A literature search and evidence synthesis was conducted via electronic databases in the English language using the key words pelviureteric junction obstruction; urolithiasis; hyperoxaluria; laparoscopic pyeloplasty; flexible nephroscopy; percutaneous nephrolithotomy, alone or in combination...
January 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28116040/mitotempo-prevents-oxalate-induced-injury-in-nrk-52e-cells-via-inhibiting-mitochondrial-dysfunction-and-modulating-oxidative-stress
#7
Jiaqiao Zhang, Qing Wang, Chuou Xu, Yuchao Lu, Henglong Hu, Baolong Qin, Yufeng Wang, Deng He, Cong Li, Xiao Yu, Shaogang Wang, Jihong Liu
As one of the major risks for urolithiasis, hyperoxaluria can be caused by genetic defect or dietary intake. And high oxalate induced renal epithelial cells injury is related to oxidative stress and mitochondrial dysfunction. Here, we investigated whether MitoTEMPO, a mitochondria-targeted antioxidant, could protect against oxalate mediated injury in NRK-52E cells via inhibiting mitochondrial dysfunction and modulating oxidative stress. MitoSOX Red was used to determine mitochondrial ROS (mtROS) production...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28073208/experience-of-percutaneous-access-under-ultrasound-guidance-in-renal-transplant-patients-with-allograft-lithiasis
#8
Silvano Palazzo, Ottavio Colamonico, Saverio Forte, Matteo Matera, Giuseppe Lucarelli, Pasquale Ditonno, Michele Battaglia, Pasquale Martino
OBJECTIVE: Urolithiasis of the transplanted kidney has an incidence of 0.2 to 1.7%, it increases the risk of infection in immunosuppressed patients and it can lead to ureteral obstruction that is often associated with deterioration of renal function. Urolithiasis of the transplanted kidney has different characteristics compared to the native kidney, due to the absence of innervation, which does not lead to colic pain. Percutaneous approach is an optimal choice in transplant patients. MATERIAL AND METHODS: Here we report our experience in two cadaveric transplant patients with urolithiasis...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28073186/factors-affecting-the-course-of-body-and-kidney-growth-in-infants-with-urolithiasis-a-critical-long-term-evaluation
#9
Kemal Sarica, Fatma Narter, Kubilay Sabuncu, Ahmet Akca, Utku Can, Ayse Buz, H Nese Sarica, Bilal Eryildirim
OBJECTIVE: To investigate the possible effects of dietary, patient and stone related factors on the clinical course of the stone disease as well as the body and renal growth status of the infants. PATIENTS AND METHODS: A total of 50 children with an history of stone disease during infancy period were studied. Patient (anatomical abnormalities, urinary tract infection - UTI, associated morbidities), stone (obstruction, UTI and required interventions) and lastly dietary (duration of sole breast feeding, formula feeding) related factors which may affect the clinical course of the disease were all evaluated for their effects on the body and renal growth during long-term follow-up...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28068846/impact-of-tamsulosin-and-nifedipine-on-contractility-of-pregnant-rat-ureters-in-vitro
#10
Lisette Haddad, Stéphanie Corriveau, Eric Rousseau, Simon Blouin, Jean-Charles Pasquier, Yves Ponsot, Marie-Ève Roy-Lacroix
OBJECTIVES: To evaluate the in vitro effect of tamsulosin and nifedipine on the contractility of pregnant rat ureters and to perform quantitative analysis of the pharmacological effects. Medical expulsive therapy (MET) is commonly used to treat urolithiasis. However, this treatment is seldom used in pregnant women since no studies support this practice. METHODS: This was an in vitro study on animal tissue derived from pregnant Sprague-Dawley rats. A total of 124 ureteral segments were mounted in an organ bath system and contractile response to methacholine (MCh) was assessed...
January 31, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27995107/evaluating-the-effectiveness-of-adding-magnesium-chloride-to-conventional-protocol-of-citrate-alkali-therapy-on-kidney-stone-size
#11
Hassan Niroomand, Amin Ziaee, Keivan Ziaee, Alaleh Gheissari
BACKGROUND: Potassium citrate (K-Cit) is one of the therapeutic solutions broadly used in patients with urolithiasis. However, recent studies have shown that it is not so effective. Therefore, the goal of our study was to evaluate the effect of a combination of K-Cit - MgCl2 oral supplements, on urinary stone size. MATERIALS AND METHODS: This study was performed on 70 asymptomatic urolithiasis cases. The supplements included K-Cit and magnesium chloride (MgCl2), purchased from (Merck Company, Germany)...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/27994853/hiv-and-kidney-diseases-35-years-of-history-and-consequences
#12
REVIEW
Pedro Campos, Alberto Ortiz, Karina Soto
Kidney diseases in human immunodeficiency virus (HIV)-infected patients are often misdiagnosed. Despite reductions in morbidity and mortality owing to widespread use of highly effective combination antiretroviral therapy (cART), acute kidney injury (AKI) and chronic kidney disease (CKD) are still more common in these patients than in the general population, and are associated with poor health outcomes. HIV-associated nephropathy and HIV immune complex kidney diseases are the more recognizable HIV-related kidney diseases...
December 2016: Clinical Kidney Journal
https://www.readbyqxmd.com/read/27993822/calcitriol-mediated-hypercalcaemia-with-silicone-granulomas-due-to-cosmetic-injection
#13
Stephen Melnick, Ana Abaroa-Salvatierra, Mrunalini Deshmukh, Arti Patel
We present a case of a 41-year-old woman with medical history significant for urolithiasis presenting to our hospital for psychiatric evaluation due to worsening depression and suicidal ideations for the past 2 weeks. Initial laboratory results show hypercalcaemia of 13.5 mg/mL that led to consulting internal medicine. On further questioning, the patient admitted to cosmetic silicone injections in her buttocks which were causing calcium deposition under her skin, leading to disfigurement of the sacrum and lumbar regions...
December 19, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27932514/long-term-therapy-with-wu-ling-san-a-popular-antilithic-chinese-herbal-formula-did-not-prevent-subsequent-stone-surgery-a-nationwide-population-based-cohort-study
#14
San-Yuan Wu, Huey-Yi Chen, Kao-Sung Tsai, Jen-Huai Chiang, Chih-Hsin Muo, Fung-Chang Sung, Yung-Hsiang Chen, Wen-Chi Chen
Traditional Chinese herbal medicine (CHM), which is widely used to treat pain and urolithiasis, is a promising therapy for urinary stone prevention. This study investigated the clinical efficacy of a popular CHM, Wu-Ling-San (WLS), in Taiwan for the prophylaxis of recurrent nephrolithiasis as assessed by surgical stone treatment via a nationwide population-based cohort study. The National Health Insurance Research Database, 2000-2010, which included one million patient records. All patients diagnosed with stone disease at the beginning of the study...
2016: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/27930581/associations-between-interventions-for-urolithiasis-and-urinary-tract-cancer-among-patients-in-taiwan-the-effect-of-early-intervention
#15
Chien-Liang Lin, Wen-Tsung Huang, Wen-Chou Fan, Yin-Hsun Feng, Chia-Ho Lin, Chian-Shiung Lin, Chih-Cheng Lu, Tse-Chou Cheng, Chao-Jung Tsao, Sheng-Hsiang Lin
The aim of this study was to investigate cancer risk in patients with a history of urolithiasis and to determine whether intervention for calculi attenuated the risk of subsequent urinary tract cancer (UTC).Using data from the National Health Insurance Research Database in Taiwan, we performed a nationwide cohort study enrolling participants (n = 42,732) aged > 30 years who were diagnosed with urinary tract calculi between 2000 and 2009. Age- and gender-matched insured individuals (n = 213,660) found in the health service records over the same period were recruited as the control group...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27915395/effect-of-potassium-citrate-supplement-on-stone-recurrence-before-or-after-lithotripsy-systematic-review-and-meta-analysis
#16
Maurício Carvalho, Bruna Olandoski Erbano, Eduardo Yukio Kuwaki, Halyson Pinheiro Pontes, Jonathan Wei Ting Wen Liu, Luis Henrique Boros, Marcelo Oliveira Asinelli, Cristina Pellegrino Baena
This meta-analysis summarizes the available evidence on the effectiveness of citrate supplement for preventing the recurrence of nephrolithiasis in patients undergoing extracorporeal shock wave lithotripsy (SWL). Electronic searches were conducted using Medline-PubMed, Web of Science, Embase, BVS (Scielo, Lilacs), and Google Scholar literature databases. The authors worked in pairs to select studies that met the following criteria: randomized controlled trials that were conducted in adults and assessed the effect of potassium citrate supplement before or after SWL therapy for urolithiasis...
December 3, 2016: Urolithiasis
https://www.readbyqxmd.com/read/27911457/what-is-the-impact-of-extracorporeal-shock-wave-lithotripsy-on-semen-parameters-a-systematic-review-and-meta-analysis
#17
Mohammad H Radfar, Nasser Simforoosh, Mehdi Sotoudeh, Mehdi H Ramezani, Mohammad J Mollakoochakian, Maryam Nikravesh, Hamidreza Shemshaki
BACKGROUND: Extracorporeal shock wave lithotripsy (ESWL) is an important tool for the management of urolithiasis. The effects of shockwaves on tissues are established. The aim of this meta-analysis is to evaluate the microscopic semen characteristics of young men before and after ESWL treatment for lower ureteral calculi. METHODS: Literature searches were performed following the Cochrane guidelines. We conducted a systematic review and meta-analysis that included six trials that investigated the effects of ESWL on semen parameters, including sperm concentration, motility, and hematospermia...
December 2, 2016: Urologia
https://www.readbyqxmd.com/read/27890522/design-and-challenges-of-a-randomized-clinical-trial-of-medical-expulsive-therapy-tamsulosin-for-urolithiasis-in-the-emergency-department
#18
Pamela K Burrows, Judd E Hollander, Allan B Wolfson, Michael C Kurz, Lorna Richards, Sara DiFiore, Phillip Watts, Nivedita Patkar, Jeremy Brown, Stephen Jackman, Ziya Kirkali, John W Kusek, Chloe Michel, Andrew C Meltzer
Urolithiasis or urinary stone disease has been estimated to affect about 1 in 11 Americans. Patients with urinary stone disease commonly present to the emergency department for management of their acute pain. In addition to providing analgesia, administration of drug (medical expulsive therapy) is often prescribed to assist passage of the urinary stone. In this methodology paper, we describe the design of a prospective, multi-center, randomized, double-blind placebo controlled clinical trial of the alpha-adrenergic blocker, tamsulosin, to evaluate its effectiveness as medical expulsive therapy...
January 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/27876212/alteration-in-oxidative-nitrosative-imbalance-histochemical-expression-of-osteopontin-and-antiurolithiatic-efficacy-of-xanthium-strumarium-l-in-ethylene-glycol-induced-urolithiasis
#19
Padma Nibash Panigrahi, Sahadeb Dey, Monalisa Sahoo, Shyam Sundar Choudhary, Sumit Mahajan
Xanthium strumarium has traditionally been used in the treatment of urolitiasis especially by the rural people in India, but its antiurolithiatic efficacy was not explored scientifically till now. Therefore, the present study was designed to validate the ethnic practice scientifically, and explore the possible antiurolithiatic effect to rationalize its medicinal use. Urolitiasis was induced in hyperoxaluric rat model by giving 0.75% ethylene glycol (EG) for 28days along with 1% ammonium chloride (AC) for first 14days...
December 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27867850/minimal-access-surgery-in-the-management-of-pediatric-urolithiasis
#20
Ana Catarina Fragoso, Henry Steyaert, Pierre Arnaud, Ciro Esposito, Jose Estevao-Costa, Jean-Stephane Valla
BACKGROUND: In contrast to adult patients, a relatively large number of open surgical procedures are still needed in the treatment of urolithiasis in children. Since almost all open surgical techniques may be reproduced by minimal access surgery (MAS), there is a rationale to apply the latter in the management of pediatric urolithiasis. Our study aimed to assess the feasibility and outcome of MAS in the treatment of pediatric urinary calculi. METHODS: The charts of patients with urolithiasis submitted to MAS between 1994 and 2007 were retrospectively reviewed...
October 2016: Translational pediatrics
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