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effectiveness urolithiasis

Sarah Prattley, James Voss, Stephanie Cheung, Robert Geraghty, Patrick Jones, Bhaskar K Somani
OBJECTIVE: To assess outcomes of ureteroscopy for treatment of stone disease in the elderly. Ureteroscopy (URS) is an increasingly popular treatment modality for urolithiasis and its applications are ever expanding with the development of newer technologies. Its feasibility and outcomes within the elderly population to our knowledge remain under-reported. MATERIALS AND METHODS: We examined the patient demographics and surgical outcomes from our prospective database for patients ≥70 years who underwent URS for urolithiasis, in a 5-year period between March 2012 and December 2016...
March 9, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Mina Cheraghi Nirumand, Marziyeh Hajialyani, Roja Rahimi, Mohammad Hosein Farzaei, Stéphane Zingue, Seyed Mohammad Nabavi, Anupam Bishayee
Kidney stones are one of the oldest known and common diseases in the urinary tract system. Various human studies have suggested that diets with a higher intake of vegetables and fruits play a role in the prevention of kidney stones. In this review, we have provided an overview of these dietary plants, their main chemical constituents, and their possible mechanisms of action. Camellia sinensis (green tea), Rubus idaeus (raspberry), Rubia cordifolia (common madder), Petroselinum crispum (parsley), Punica granatum (pomegranate), Pistacia lentiscus (mastic), Solanum xanthocarpum (yellow-fruit nightshade), Urtica dioica (stinging nettle), Dolichos biflorus ( horse gram ), Ammi visnaga (khella), Nigella sativa (black-cumin), Hibiscus sabdariffa (roselle), and Origanum vulgare (oregano) have received considerable interest based on scientific evidence...
March 7, 2018: International Journal of Molecular Sciences
Fatih Yanaral, Omer Sarilar
No abstract text is available yet for this article.
March 6, 2018: Urologia Internationalis
Metin Gündüz, Tamer Sekmenli, İlhan Ciftci, Ahmet Midhat Elmacı
No abstract text is available yet for this article.
March 6, 2018: Urologia Internationalis
Zhen-Lang Guo, Jun-Yue Wang, Lei-Liang Gong, Shu Gan, Chi-Ming Gu, Shu-Sheng Wang
BACKGROUND: We performed a meta-analysis to determine whether a consistent relationship exists between cadmium exposure and urolithiasis in humans. Accordingly, we summarized and reviewed previously published quantitative studies. METHODS: Eligible studies with reference lists published before June 1, 2017 were obtained from searching several databases. Random effects models were used to summary the overall estimate of the multivariate adjusted odds ratios (ORs) with 95% confidence intervals (CIs)...
January 2018: Medicine (Baltimore)
Yunhe Yen, Borshuh Cheng, Changchung Chan, Chiwei Lin, Hsiuling Chen
Lifestyle, food intake, and exposure to chemicals are potential risk factors for the development of calcium urolithiasis. Pb, Cd, and Hg have been proved to cause renal illness, and urinary tract stones might be caused by exposure to metals. Therefore, this study aimed to measure the concentration of metals in urinary tract stones and blood simultaneously in urolithiasis patients. Moreover, we intended to determine whether urinary tract stones can be regarded as a biomarker of exposure or an effect marker in a population with environmental exposure to metals...
February 27, 2018: Biological Trace Element Research
Daniel Gerber, Catherine S Forster, Michael Hsieh
PURPOSE OF REVIEW: In this review, we highlight the effects of the microbiome on urologic diseases that affect the pediatric patient. RECENT FINDINGS: Perturbations in the urinary microbiome have been shown to be associated with a number of urologic diseases affecting children, namely urinary tract infection, overactive bladder/urge urinary incontinence, and urolithiasis. Recently, improved cultivation and sequencing technologies have allowed for the discovery of a significant and diverse microbiome in the bladder, previously assumed to be sterile...
February 22, 2018: Current Urology Reports
Hsiang-Chun Lai, Hung-Jen Lin, Sheng-Teng Huang
OBJECTIVE: Urolithiasis is a common medical condition affecting the urinary tract. Typical symptoms reported by patients include colic pain and hematuria. Some patients may undergo surgical intervention or lithotripsy to remove the stones. In this case, we demonstrated that Chinese herbal medicine (CHM) was an effective modality to remove stones in a patient with urolithiasis. CLINICAL FEATURES AND OUTCOME: A 47-year-old man suffered from right flank pain and hematuria for three months and was diagnosed with an upper third ureteral stone obstruction with right hydronephrosis...
February 2018: Complementary Therapies in Medicine
Xiangquan Zeng, Yu Xi, Weibo Jiang
In the urinary system, urolithiasis is the third prevalent disorder which causes severe pain in individuals. Urinary stones are composed of calcium oxalate (CaOx) and calcium phosphate in approximately 80% of patients. Although various drugs and surgery operations are used to treat the disease, side effects of drugs and the high recurrence after therapy in patients cannot be ignored. Flavonoids are a large group of plant polyphenols with presumed beneficial effects on several common diseases. Whereas, a very few have reached clinical use...
February 12, 2018: Critical Reviews in Food Science and Nutrition
Andrew J Cohen, Melanie A Adamsky, Charles U Nottingham, Jaclyn Pruitt, Brittany Lapin, Chi H Wang, Sangtae Park
OBJECTIVES: To determine whether statin intake affects nephrolithiasis risk, and whether higher lipid levels correlate with stone risk. Dyslipidemia is a known independent risk factor for urolithiasis, and emerging evidence suggests common biological pathways. Previous work has suggested that statins protect against new stone formation, but these findings have not been verified by other investigators. METHODS: We queried our Institution's Electronic Data Warehouse for all patients who were newly diagnosed with hyperlipidemia between 2009 and 2011, and had never taken a statin drug...
February 5, 2018: Urology
K M Muhammed Shameem, Arun Chawla, Madhukar Mallya, Bijay Kumar Barik, V K Unnikrishnan, V B Kartha, C Santhosh
Presence of renal calculi (kidney stones) in human urethra is being increasingly diagnosed over the last decade and is considered as one of the most painful urological disorders. Accurate analysis of such stones plays a vital role in the evaluation of urolithiasis patients and in turn helps the clinicians toward exact etiologies. Two highly complementary laser-based analytical techniques; Laser Induced Breakdown Spectroscopy (LIBS) and micro-Raman spectroscopy have been used to identify the chemical composition of different types of renal calculi...
February 7, 2018: Journal of Biophotonics
Julius Matthias Weinrich, Peter Bannas, Marc Regier, Sarah Keller, Luis Kluth, Gerhard Adam, Frank Oliver Henes
OBJECTIVE: The purpose of this study is to assess the diagnostic yield of low-dose (LD) CT for alternative diagnoses in patients with suspected urolithiasis. MATERIALS AND METHODS: In this retrospective study, we included 776 consecutive patients who underwent unenhanced abdominal CT for evaluation of suspected urolithiasis. All examinations were performed with an LD CT protocol; images were reconstructed using iterative reconstruction. The leading LD CT diagnosis was recorded for each patient and compared with the final clinical diagnosis, which served as the reference standard...
January 24, 2018: AJR. American Journal of Roentgenology
Rita López-Cabanillas, Ronal Huayanay-Conde, Cinthya Gonzales, Mahli Maguiña, Italo Granados, Mila Ccasani, Astrid Laguna, Ernesto León, Nuria Romero-Caballero, Jessenia Chacón
OBJECTIVES: To determine the antiurolytic activity of the ethanolic extract of Ayacuchan propolis in a preventive model of urolithiasis in rats. MATERIALS AND METHODS: A total of 45 male Sprague-Dawley albino rats were studied. The antiurolithic effect was analyzed in five groups of six animals each: blank, control (treated with 1 mL of 5% ethylene glycol and 1 mL of 5% ammonium chloride), and three experimental groups (treated with the ethanol extract of propolis at a daily dose of 250, 350, and 500 mg/kg, respectively)...
October 2017: Revista Peruana de Medicina Experimental y Salud Pública
Tsai-Hung Wu, Ko-Jen Li, Chia-Li Yu, Chang-Youh Tsai
Tamm-Horsfall protein (THP), or uromodulin (UMOD), is an 80-90-kDa phosphatidylinositol-anchored glycoprotein produced exclusively by the renal tubular cells in the thick ascending limb of the loop of Henle. Physiologically, THP is implicated in renal countercurrent gradient formation, sodium homeostasis, blood pressure regulation, and a defense molecule against infections in the urinary system. Investigations have also revealed that THP is an effective binding ligand for serum albumin, immunoglobulin G light chains, complement components C1 and C1q, interleukin (IL)-1β, IL-6, IL-8, tumor necrosis factor (TNF)-α, and interferon-γ through its carbohydrate side chains for maintaining circulatory and renal immune homeostasis...
January 22, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Hirotaka Iwaki, Rina Ando, Noriyuki Miyaue, Satoshi Tada, Tomoaki Tsujii, Hayato Yabe, Noriko Nishikawa, Masahiro Nagai, Masahiro Nomoto
BACKGROUND: Epidemiological studies have repeatedly reported that increased serum urate level is associated with a slower progress of Parkinson's disease (PD). The urate precursor, inosine, raises the serum urate level and is therefore a candidate for a disease modifying treatment. However, an elevated serum urate level is a risk factor for gout, urolithiasis, and cardiovascular diseases. Although there have been previous clinical studies, the use of inosine in a clinical setting is still limited, and its safety is unclear, especially in an Asian population...
December 15, 2017: Journal of the Neurological Sciences
Jeffrey C Morrison, Jason P Van Batavia, Kassa Darge, Christopher J Long, Aseem R Shukla, Arun K Srinivasan
INTRODUCTION: Ureteroscopy has been shown to be a highly efficacious and safe modality for the treatment of pediatric urolithiasis. However, conventional ureteroscopy relies on fluoroscopy for intraoperative guidance, exposing both patient and operating room personnel to ionizing radiation. Pediatric urolithiasis patients are at a particularly increased risk from this radiation exposure. The use of ultrasound in place of fluoroscopy for intraoperative guidance has emerged as one modification that can reduce radiation exposure during ureteroscopy...
October 14, 2017: Journal of Pediatric Urology
Junchuan Yu, Yaoliang Deng, Zhiwei Tao, Weixia Liang, Xiaofeng Guan, Jihua Wu, Xin Ning, Yunlong Liu, Quan Liu, Ziqi He
This study developed an in vitro system by co-culturing HK-2 cells with different concentration of hydroxyapatite (HAP) and/or macrophage cells to simulate the internal environment of urolithiasis as far as possible, investigating the regulatory effects of macrophage cells on HAP-induced expression of relative inflammatory factors of HK-2 cells. The control group (H group) was only comprised of HK-2 cells. Experimental groups included co-culturing HK-2 cells and macrophage cells (H + M group), co-culturing HK-2 cells and HAP (H + A group), co-culturing macrophage cells and HAP (M + A group), and co-culturing HK-2 cells and macrophage cells with HAP (H + M + A group)...
December 13, 2017: Urolithiasis
Bora Özveren, Murat Tugrul Eren, Hakan Özveri, Uğur Altuğ, Ahmet Şahin
Objectives: To assess treatment effectiveness and safety of bilateral same-session ureterorenoscopy (BSSU) for the management of stone disease involving the entire urinary system. Patients and methods: We reviewed the records of 64 patients who underwent BSSU for the treatment of bilateral ureteric and/or kidney stones. Size, number, location per side, and the total burden of stones were recorded. Data on stenting, lithotripsy, and stone retrieval, and details of hospital stay and operation times were investigated...
December 2017: Arab Journal of Urology
Panagiotis Kallidonis, Dimitrios Kotsiris, Francesco Sanguedolce, Panteleimon Ntasiotis, Evangelos Liatsikos, Athanasios Papatsoris
Objective: To review the literature on the effectiveness, safety and long-term patency of ureteric metal mesh stents (MSs), as a variety of MSs have been used for managing malignant ureteric obstruction over the last three decades. Materials and methods: A systematic review using the search string; Ureter∗ AND (stent OR endoprosthesis) AND metal∗ was conducted on PubMed, Scopus, Web of science and Cochrane Library online databases in May 2016. Prospective, retrospective, and comparative studies including MSs were included...
December 2017: Arab Journal of Urology
Carrie Johans, Woodson Smelser, Chelsea DeRoche, Jack Campbell, James Cummings
PURPOSE: With advances in technology, ureteroscopy (URS) is increasingly utilized for the management of urolithiasis. Previous studies have attempted to characterize the post-operative complication and readmission rates relative to the technical difficulty of the procedure. There is limited data exploring the resident level of training and its effect on adverse outcomes in these cases. We review our experience with URS to create a model to predict factors, including resident experience, that affect rates of post-operative complications...
February 2018: Journal of Endourology
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