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effectiveness urolithiasis

Ravindra D Hiremath, Sunil S Jalalpure
OBJECTIVE: Aim of this study is to evaluate antiurolithiatic potential of whole plant hydro-alcoholic (30:70) extract of Vernonia cinerea Less. in accordance to its claims made in ancient literature and also being one of the ingredients of cystone, a marketed formulation widely used in the management of urolithiasis. MATERIALS AND METHODS: To induce urolithiasis, 0.75% v/v ethylene glycol was administered orally for 14 days. The curative dose of 400 mg/kg b.w. and preventive doses of 100, 200, and 400 mg/kg b...
July 2016: Indian Journal of Pharmacology
Mordechai Duvdevani
Endoscopic treatment is currently the mainstay of management for urolithiasis. The high effectiveness of PCNL is well documented in the literature, as are its complications. Bleeding during PCNL is directly related to the size of the dilatation.(1) Several minimally invasive refinements in percutaneous surgery have been made to reduce access related complications and bleeding rates.(2) This was achieved mainly by reducing tract diameter, but the advantage over standard PCNL has yet to be proven.(3) The effectiveness of RIRS is decreasing with increasing stone burden...
October 12, 2016: Journal of Endourology
Chang Kyu Sung, Min Hoan Moon, Hwancheol Son, Sohee Oh, Myoung Seok Lee, Hyunsik Woo
PURPOSE: To assess the effectiveness of reduced-radiation-dose computed tomography (CT) protocols in the tracing of the ureter in patients with suspected renal colic. METHODS: The study was approved by our institutional review board, and informed consent was obtained from the participants. From July 2012 to April 2014, 310 consecutive patients with suspected urolithiasis were recruited to undergo unenhanced CT at 280 (n = 62), 200 (n = 62), 140 (n = 62), 100 (n = 62), and 70 (n = 62) reference mA seconds (mAs) while keeping other imaging parameters constant...
October 11, 2016: Abdominal Radiology
Deepika Aggarwal, Diksha Gautam, Minu Sharma, S K Singla
Bergenin, isolated from Bergenia ligulata is a potent antioxidant and antilithiatic agent. Present work was designed to establish the biochemical role of bergenin on mitochondrial dysfunction in the ethylene glycol induced hyperoxaluric rat model. Bergenin was administrated at a dose of 10mg/kg body wt i.p. from 14th day of establishing the 28 days hyperoxaluria rat model. α-Tocopherol was given as positive control at a dose of 100mg/kg body wt i.p. Mitochondrial dysfunction was studied by evaluating the activities of respiratory chain complexes, mitochondrial membrane potential and reactive oxygen species...
October 5, 2016: European Journal of Pharmacology
Akbar Nouralizadeh, Abbas Basiri, Seyed Amir Mohsen Ziaee, Ali Tabibi, Farzaneh Sharifiaghdas, Behzad Narouie, Reza Sarhangnejad, Reza Valipour, Mehdi Sotoudeh, Hamidreza Shemshaki, Nooshin Ketabi, Saeed Movahed
BACKGROUND: Using percutaneous nephrolitotomy (PCNL) with large adult instruments in treatment of pediatricurolithiasis is still in debate. This study was conducted to evaluate the efficacy and safety of PCNL with adult's instrument in treatment of patients less than 3 years old. METHODS: Data on patient characteristics and outcomes for 261 consecutive children undergoing PCNL at a Labbafinejad University Hospital were collected prospectively from September 2006 to February 2016...
October 1, 2016: Urologia
Vansh Kapila, Ayush K Kapila, Thomas Tailly, Bernard Rappe, Kristian Vinter Juul, Karel Everaert
Urolithiasis is a frequent problem causing a significant clinical, psychological and socio-economic burden. Analgesia remains the most important element in the medical treatment of renal colic. Nonetheless, both NSAIDs and opiates have a side effect profile which can cause further complications. As such, the use of desmopressin for renal colic has received increased attention in the last two decades. This paper provides an overview of current evidence on the use of desmopressin as an analgesic strategy in renal colic...
September 23, 2016: Acta Clinica Belgica
Amisha Mittal, Simran Tandon, Surender Kumar Singla, Chanderdeep Tandon
Kidney stone formation during hyperoxaluric condition is inherently dependent on the interaction between renal epithelial cells and calcium oxalate (CaOx) crystals. Although modern medicine has progressed in terms of removal of these stones, recurrence and persistent side effects restricts their use. Strategies involving plant based agents which could be used as adjunct therapy is an area which needs to be explored. Plant proteins having antilithiatic activity is a hitherto unexplored area and therefore, we conducted a detailed identification and characterization of antilithiatic proteins from Terminalia arjuna (T...
2016: PloS One
Theodora Stasinou, Andreas Bourdoumis, Junaid Masood
OBJECTIVES: To investigate a possible causal relationship for stone formation in pelviureteric junction obstruction and to outline management options. MATERIALS AND METHODS: A literature search and evidence synthesis was conducted via electronic databases in the English language using the key words pelviureteric junction obstruction; urolithiasis; hyperoxaluria; laparoscopic pyeloplasty; flexible nephroscopy; percutaneous nephrolithotomy, alone or in combination...
September 20, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
Ali Pourmand, Rahul Nadendla, Maryann Mazer-Amirshahi, Francis O'Connell
In the United States, urolithiasis affects approximately 1 in 11 people, and there is evidence that the prevalence is increasing. A relatively recent treatment strategy for urolithiasis involves using medical expulsive therapy (MET) to increase the likelihood of spontaneous passage of ureteral stones. The 2 leading drug classes for MET are alpha-1-andrenergic receptor blockers and calcium channel blockers. Tamsulosin, an alpha-1-adrenocepter blocking agent, is thought to induce spontaneous stone passage by relaxing ureteral smooth muscle tone...
September 8, 2016: American Journal of Emergency Medicine
A Neisius, C Thomas, F C Roos, W Jäger, I Tsaur, G Bartsch, T Knoll, A Haferkamp
BACKGROUND: Urolithiasis is a widespread disease. Diagnostic imaging plays an important role in the evaluation and management of patients with suspected urolithiasis. Furthermore, modern imaging methods may provide information on stone location, size, fragility and composition aiding the urologist to determine the appropriate treatment modality. PURPOSE: Based on the current literature and guidelines, this review reports on the various new and established diagnostic imaging modalities...
October 2016: Der Urologe. Ausg. A
Predrag Ilic, Miroslav Djordjevic, Vladimir Kojovic, Slobodan Dzambasanovic
AIM: To evaluate the effectiveness and safety of laser lithotripsy in the treatment of renal stones in children in a single center. MATERIAL AND METHODS: We retrospectively analysed patients (n=36) who were treated with laser nephrolithotripsy (LL group) between 2011 and 2014. We compared those results with results of pneumatic nephrolithotripsy in patients (n=32) who were treated from 2007 to 2011 (PL group). The patients were evaluated in respect of gender, age, stone location, stone size, complications and stone-free rate...
July 22, 2016: Annali Italiani di Chirurgia
Aaron F Brafman, Marla J Wardenburg, Vincent Bird
BACKGROUND: Endourology is a widely used means by which to manage urolithiasis. Patient anatomy can oftentimes limit what can be accomplished with current technology. CASE PRESENTATION: This is a case of a patient with renal and ureteral stones within a transplant kidney. Her anatomy would not allow for a standard retrograde ureteroscopic approach. We describe a method by which to overcome this difficult scenario by using a rigid cystoscope as a platform by which a ureteroscope was passed to allow for stone removal...
2016: J Endourol Case Rep
Frederikke Eichner Christiansen, Kim Hovgaard Andreassen, Palle Jörn Sloth Osther
Often when calcite is found as a component of urinary calculi, they are considered false calculi or artifacts. We present a case of true calcite urolithiasis. The stone material was removed percutaneously from a severely malnourished anorectic woman and analyzed by infrared spectroscopy (IRS). In addition, calcite urolithiasis was confirmed in several recurrent stone events by IRS. Laxative abuse with magnesium oxide was believed to be the underlying cause of stone formation, and ammonium chloride given as one weekly dose turned out to be effective for stone prevention...
2016: J Endourol Case Rep
Alfonso Benincasa, Federico Nicolosi, Mario Falsaperla, Alberto Saita
BACKGROUND: Recently endoscopic combined intrarenal surgery (ECIRS) has been introduced as an innovative approach for the treatment of complex single, multiple, and staghorn urolithiasis, which reveals to be a viable alternative to standard percutaneous nephrolithotomy. Although considered to be a versatile, safe, and efficient endoscopic procedure, it is not free from complications. We would like to report two rare cases of hydroperitoneum that occurred during ECIRS and their management...
2016: J Endourol Case Rep
Joseph W Bartges
PRACTICAL RELEVANCE: Uroliths occur commonly in the bladder and/or urethra of cats and can be lifethreatening if urethral obstruction occurs. Calcium oxalate accounts for 40-50% of urocystoliths and these stones are not amenable to medical dissolution; therefore, removal by surgery or minimally invasive techniques is required if uroliths must be treated. Medical protocols for prevention involve decreasing urine saturation for minerals that form uroliths. ETIOPATHOGENESIS: Formation of uroliths is not a disease, but rather a complication of several disorders...
September 2016: Journal of Feline Medicine and Surgery
P Nguyen, B Reynolds, J Zentek, N Paßlack, V Leray
High sodium levels in cat food have been controversial for a long time. Nonetheless, high sodium levels are used to enhance water intake and urine volume, with the main objective of reducing the risk of urolithiasis. This article is a review of current evidence of the putative risks and benefits of high dietary sodium levels. Its secondary aim is to report a possible safe upper limit (SUL) for sodium intake. The first part of the manuscript is dedicated to sodium physiology, with a focus on the mechanisms of sodium homeostasis...
August 23, 2016: Journal of Animal Physiology and Animal Nutrition
B K Somani, G Giusti, Y Sun, P J Osther, M Frank, M De Sio, B Turna, J de la Rosette
INTRODUCTION: Ureterorenoscopy (URS) is a popular and growing option for management of ureteric and renal stones. The CROES URS Global Study was set up to assess the outcomes of URS in a large worldwide cohort of patients involving multiple centres. In this paper, we analysed the database for intra-operative and post-operative complications associated with ureterorenoscopy. METHODS: The CROES database was established via collaboration between 114 centres in 32 countries worldwide, and information on both intra-operative and post-operative complications was collected electronically between January 2010 and October 2012...
August 4, 2016: World Journal of Urology
Jian Gao, Fei Wang, Xinyu Kuang, Rong Chen, Jia Rao, Bin Wang, Wenyan Li, Haimei Liu, Qian Shen, Xiang Wang, Hong Xu
BACKGROUND: The illegal use of melamine in powdered baby formula resulted in a widespread outbreak of melamine-associated pediatric urolithiasis and kidney damage in China in 2008. We conducted this study because more needs to be known about the long-term effects of melamine-associated urolithiasis and kidney damage. OBJECTIVES: To determine the prognosis and long-term implications of chronic kidney damage in children with urolithiasis resulting from melamine consumption...
July 2016: Annals of Saudi Medicine
Ahmad Majzoub, Ammar Al-Ani, Tawiz Gul, Hatem Kamkoum, Khalid Al-Jalham
AIM: Shock wave lithotripsy (SWL) is a well-established modality in the treatment of urolithiasis. Studying the effect of urine pH on SWL success is appealing as pH can be manipulated before SWL to insure a better outcome. MATERIALS AND METHODS: This is a prospective study performed at a tertiary medical center. Patients presenting to the SWL unit with a single renal stone <2 cm in size were included in this study. In addition to standard laboratory and radiologic investigations, urine pH measurement was performed on all patients before their procedure...
July 2016: Urology Annals
Scott A Katzman, Betsy Vaughan, Jorge E Nieto, Larry D Galuppo
OBJECTIVE To evaluate the use of a laparoscopic specimen retrieval pouch for removal of intact or fragmented cystic calculi from standing horses. DESIGN Retrospective case series. ANIMALS 8 horses (5 geldings and 3 mares) with cystic calculi. PROCEDURES Physical examination and cystoscopic, ultrasonographic, and hematologic evaluations of urinary tract function were performed for each horse. A diagnosis of cystic calculus was made on the basis of results of cystoscopy and ultrasonography. Concurrent urolithiasis or other urinary tract abnormalities identified during preoperative evaluation were recorded...
August 1, 2016: Journal of the American Veterinary Medical Association
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