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https://www.readbyqxmd.com/read/29447949/protective-effects-of-alpinae-oxyphyllae-fructus-extracts-on-lipopolysaccharide-induced-animal-model-of-alzheimer-s-disease
#1
Yunlong Wang, Mengshi Wang, Kaiyue Fan, Tongde Li, Tingxu Yan, Bo Wu, Kaishun Bi, Ying Jia
ETHNOPHARMACOLOGICAL RELEVANCE: Alpinae Oxyphyllae Fructus (AOF) with warming and tonifying the kidney and spleen, anti-salivation, anti-polyuria and anti-diarrhea functions is the dried ripe fruits of Alpinia oxyphylla Miq. (Zingiberaceae). As a traditional Chinese medicine, its application history is very long. AIMS OF THE STUDY: The purpose of our study is to investigate the effects of different solvent extracts from AOF on lipopolysaccharide (LPS)-induced animal model of Alzheimer's disease (AD) to elucidate the traditional medical theories with modern pharmacological methods and provide a reference for further clarifying its active components and mechanisms...
February 12, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29444579/-quality-of-nephrolithiasis-surgical-treatment-what-is-it-influenced-by
#2
V Kováčik, M Maciak, P Bujdák, V Baláž, R Školka, M Rusňák
INTRODUCTION: Identifying factors effecting the quality of nephrolithiasis surgical treatment could improve medical care for patients suffering from kidney stone disease. The objective of the article is to identify factors influencing reintervention rate after surgical treatment of kidney stone disease either by percutaneous nephrolitholapaxy or flexible ureterorenoscopy. METHOD: A retrospective study was conducted on 149 patients who underwent a surgery for a kidney stone disease at the Urological department of F...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29440373/calcium-supplementation-in-osteoporosis-useful-or-harmful
#3
Iacopo Chiodini, Mark J Bolland
Osteoporosis and fragility fractures are important social and economic problems worldwide and are due to both the loss of bone mineral density and sarcopenia. Indeed, fragility fractures are associated with increased disability, morbidity and mortality. It is known that a normal calcium balance together with a normal vitamin D status is important for maintaining well-balanced bone metabolism and for many years calcium and vitamin D has been considered crucial in the prevention and treatment of osteoporosis...
February 12, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29437013/topiramate-induced-limbs-paraesthesia-and-rigid-fingers-flexion
#4
Andrea Domenico Pratico, Martino Ruggieri, Raffaele Falsaperla, Piero Pavone
Topiramate is a well-known anticonvulsant drug with a broad spectrum of actions. It has been proposed in the treatment of several types of epileptic seizures both in monotherapy and in add-on. Its usage has been extended to other disorders including migraine, essential tremor, obesity, alcohol and drug addiction. The most frequent side-effects of topiramate include dizziness, somnolence, insomnia, and ataxia. Paraesthesia, metabolic acidosis, kidney stones, hypohidrosis, cognitive impairment and eye symptoms have been also reported...
February 12, 2018: Current Drug Safety
https://www.readbyqxmd.com/read/29435125/inhibition-of-autophagy-attenuated-calcium-oxalate-crystal-induced-renal-tubular-epithelial-cell-injury-in-vivo-and-in-vitro
#5
Yunlong Liu, Derong Li, Ziqi He, Quan Liu, Jihua Wu, Xiaofeng Guan, Zhiwei Tao, Yaoliang Deng
Accumulating evidence suggests that autophagy is involved in the pathophysiological processes of kidney diseases. However, the role of autophagy in the formation of calcium oxalate (CaOx) nephrolithiasis remains unclear. In this study, we investigated the effects of autophagy on renal tubular epithelial cell injury induced by CaOx crystals in vivo and in vitro . We first observed that the expression levels of LC3-II and BECN1 and number of autophagic vacuoles were markedly increased in the renal tissue of CaOx stone patients...
January 12, 2018: Oncotarget
https://www.readbyqxmd.com/read/29434824/clinical-importance-of-chemokines-and-inflammatory-cytokines-for-patient-care-following-percutaneous-nephrolithotripsy
#6
Junrong Wang, Wei Wang, Wei Guo, Yanru Ma, Tianhui Ji, Baodi Zhang
Chemokines are a class of proteins with low molecular weight that serve important roles in the progression of inflammation. Percutaneous nephrolithotripsy is a surgical technique in which lasers or ultrasound are utilized to break down and/or remove kidney stones. In order to ensure a full recovery following surgery, effective patient care and nursing are required. In the present study, a total of 348 patients with kidney stones were recruited and the clinical importance of chemokines and inflammatory cytokines for the nursing of patients during perioperative period was investigated...
February 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29421299/impact-of-statin-intake-on-kidney-stone-formation
#7
Andrew J Cohen, Melanie A Adamsky, Charles U Nottingham, Jaclyn Pruitt, Brittany Lapin, Chi H Wang, Sangtae Park
OBJECTIVES: To determine whether statin intake affects nephrolithiasis risk, and whether higher lipid levels correlate with stone risk. Dyslipidemia is a known independent risk factor for urolithiasis, and emerging evidence suggests common biological pathways. Previous work has suggested that statins protect against new stone formation, but these findings have not been verified by other investigators. METHODS: We queried our Institution's Electronic Data Warehouse for all patients who were newly diagnosed with hyperlipidemia between 2009 and 2011, and had never taken a statin drug...
February 5, 2018: Urology
https://www.readbyqxmd.com/read/29416282/incidence-and-characteristics-of-kidney-stones-in-patients-with-horseshoe-kidney-a-systematic-review-and-meta-analysis
#8
Aditya S Pawar, Charat Thongprayoon, Wisit Cheungpasitporn, Ankit Sakhuja, Michael A Mao, Stephen B Erickson
Introduction: The horseshoe kidney (HSK) is the most common type of renal fusion anomaly. The incidence and characteristics of kidney stones in patients with HSK are not well studied. The aim of this meta-analysis was to evaluate the incidence and types of kidney stones in patients with HSK. Methods: A systematic literature search was performed using MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews from the databases' inception through November 2016...
January 2018: Urology Annals
https://www.readbyqxmd.com/read/29411942/libs-raman-an-effective-complementary-approach-to-analyze-renal-calculi
#9
K M Muhammed Shameem, Arun Chawla, Madhukar Mallya, Bijay Kumar Barik, V K Unnikrishnan, V B Kartha, C Santhosh
Presence of renal calculi (kidney stones) in human urethra is being increasingly diagnosed over the last decade and is considered as one of the most painful urological disorders. Accurate analysis of such stones plays a vital role in the evaluation of urolithiasis patients and in turn helps the clinicians toward exact etiologies. Two highly complementary laser-based analytical techniques; Laser Induced Breakdown Spectroscopy (LIBS) and micro-Raman spectroscopy have been used to identify the chemical composition of different types of renal calculi...
February 7, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29399012/value-of-magnetic-resonance-urography-versus-computerized-tomography-urography-ctu-in-evaluation-of-obstructive-uropathy-an-observational-study
#10
Saeed M Bafaraj
Background: Obstructive uropathy is a common public health issue that requires imaging research for providing necessary information. The data is important for determining treatment options, and may influence selective management choices. Objective: The aim of the study is to determine whether magnetic resonance urography or computerized tomography urography is the best imaging modality among patients with suspected obstructive uropathy. Methods: Seventy patients; referred from the emergency department for the evaluation of renal colic or hematuria that highly suggested urinary tract abnormalities, were prospectively enrolled...
February 2018: Current Medical Imaging Reviews
https://www.readbyqxmd.com/read/29393127/uric-acid-renal-lithiasis-new-concepts
#11
Fabiola Pazos Pérez
BACKGROUND: Uric acid (UA) stones are responsible for 5-10% of the formation of all kidney stones. Recently, an association between UA stones and insulin resistance, diabetes mellitus, and obesity has been demonstrated and so the incidence has increased. The development of UA stones is dependent on several risk factors, including genetic predisposition, geographical location, dietary indiscretion, and various metabolic characteristics. SUMMARY: UA nephrolithiasis can arise from diverse etiologies, all with distinct underlying defects converging to one or more of 3 defects of hyperuricosuria, acidic urine pH, and low urinary volume...
2018: Contributions to Nephrology
https://www.readbyqxmd.com/read/29390476/ultrasound-guided-percutaneous-nephrolithotomy-for-the-treatment-in-patients-with-kidney-stones
#12
Wei Sun, Ming-Nan Liu, Zhi-Wei Yang, Qi Wang, Ying Xu
BACKGROUND: In this study, we aimed to explore the effect of ultrasound-guided percutaneous nephrolithotomy (UGPN) for the treatment in patients with kidney stones (KS). METHODS: We randomly assigned 86 patients with KS to a UGPN group or a control group, each group comprising 43 patients. Patients from the UGPN group underwent UGPN whereas those from control group underwent fluoroscopic-guided percutaneous nephrolithotomy (FGPN). The primary outcome included the stone-free rate...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29387552/effect-of-blumea-balsamifera-extract-on-the-phase-and-morphology-of-calcium-oxalate-crystals
#13
Charlimagne M Montealegre, Rizalinda L De Leon
Objective: Calcium oxalate crystals are found in majority of kidney stones with calcium oxalate monohydrate (COM) as one of the primary types of kidney stones. Various methods of treatment exist, including herbal treatment in the Philippines that uses the medicinal herb Blumea balsamifera (B. balsamifera). Methods: The effect of B. balsamifera extract on the morphology of calcium oxalate crystals was studied by light microscopy, image analysis, powder X-ray diffraction and scanning electron microscopy...
October 2017: Asian Journal of Urology
https://www.readbyqxmd.com/read/29383330/bilateral-prone-percutaneous-nephrolithotomy-under-epidural-in-candidate-for-lung-transplant-case-report-and-review-of-literature
#14
Ricardo Manuel de Oliveira Soares, Alexander Paul Glaser, Jason Evan Cohen, Obianuju Okocha, Robert Brewster Nadler
Background: Percutaneous nephrolithotomy (PCNL) is a procedure typically performed under general anesthesia (GA); however, many patients might be considered unfit for GA and locoregional anesthesia is their only chance to have the procedure done. Case Presentation: A 60-year-old Middle-Eastern female with end-stage lung disease underwent evaluation for lung transplant; she was found to have severe restrictive pattern on steroid and continuous oxygen therapy, pulmonary hypertension with dilated right ventricle, chronic anemia, and asthma...
2018: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29376598/-analysis-of-clinical-effectiveness-and-risk-factors-for-complication-of-percutaneous-nephrolototripsia-in-patients-with-a-solitary-kidney
#15
L D Arustamov, M I Katibov, D S Merinov, Sh Sh Gurbanov, A V Artemov, V A Epishov
RELEVANCE: Management of patients with large and staghorn stones of a solitary kidney is widely debated among urologists and has not been sufficiently investigated, which determined the relevance of this study. MATERIALS AND METHODS: The study comprised 80 patients with large (>20 mm) and staghorn stones of an anatomically or functionally solitary kidney. Of them, 58 patients underwent percutaneous nephrolithotripsy (PNL), and 22 had open surgery. The criterion of the treatment effectiveness was the complete stone clearance or small residual fragments sized less than 3 mm...
December 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29368229/viability-and-biocompatibility-of-an-adhesive-system-for-intrarenal-embedding-and-endoscopic-removal-of-small-residual-fragments-in-minimally-invasive-stone-treatment-in-an-in-vivo-pig-model
#16
Simon Hein, Dominik Stefan Schoeb, Ingo Grunwald, Katharina Richter, Jörg Haberstroh, Maximilian Seidl, Peter Bronsert, Ulrich Wetterauer, Martin Schoenthaler, Arkadiusz Miernik
PURPOSE: To evaluate the viability and biocompatibility of a novel, patented bioadhesive system for intrarenal embedding and retrieval of residual fragments after endoscopic lithotripsy. Complete stone clearance via active removal of residual fragments (RF) after intracorporeal laser lithotripsy may be time-consuming and fail in many cases. Therefore, the novel adhesive has been developed and evaluated for the first time in an in vivo pig model in the present work. METHODS: Four female domestic pigs underwent flexible ureteroscopy (RIRS) or percutaneous nephrolithotomy (PNL) under general anesthesia (8 kidneys, 4 × RIRS, 4 × PNL) evaluating the bioadhesive system...
January 24, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29364405/-antiurolithic-activity-of-the-ethanolic-extract-of-ayacuchano-propolis-in-rats
#17
Rita López-Cabanillas, Ronal Huayanay-Conde, Cinthya Gonzales, Mahli Maguiña, Italo Granados, Mila Ccasani, Astrid Laguna, Ernesto León, Nuria Romero-Caballero, Jessenia Chacón
OBJECTIVES: To determine the antiurolytic activity of the ethanolic extract of Ayacuchan propolis in a preventive model of urolithiasis in rats. MATERIALS AND METHODS: A total of 45 male Sprague-Dawley albino rats were studied. The antiurolithic effect was analyzed in five groups of six animals each: blank, control (treated with 1 mL of 5% ethylene glycol and 1 mL of 5% ammonium chloride), and three experimental groups (treated with the ethanol extract of propolis at a daily dose of 250, 350, and 500 mg/kg, respectively)...
October 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/29363092/the-tolerability-of-potassium-citrate-tablet-in-patients-with-intolerance-to-potassium-citrate-powder-form
#18
Abbas Basiri, Fatemeh Taheri, Maryam Taheri
PURPOSE: To assess the tolerability of Potassium Citrate (KCit) tablet in patients with kidney stones that were not able to use the powder form of this drug due to unfavorable salty taste and gastrointestinal complications. MATERIALS AND METHODS: Twenty-three stone formers, with intolerance to potassium citrate powder form, which had referred to Labbafinejad stone preventive clinic (2015), have been included in this study. All of the patients took two Potassium citrate tablets (10 meq), three times a day for two weeks...
January 23, 2018: Urology Journal
https://www.readbyqxmd.com/read/29362656/clinical-efficacy-and-safety-of-transcatheter-embolization-for-vascular-complications-after-percutaneous-nephrolithotomy
#19
Necdet Poyraz, Mehmet Balasar, İbrahim Erdem Gökmen, Osman Koç, Mehmet Giray Sönmez, Arif Aydın, Yunus Emre Göger, Ahmet Öztürk
Introduction: Percutaneous nephrolithotomy (PNL) is the preferred procedure for safe and effective surgical treatment of kidney stones. Hemorrhage is the most serious complication of PNL, resulting from pseudoaneurysm (PA) or arteriovenous fistula (AVF), and can usually be controlled with conservative treatment. Aim: To evaluate endovascular treatments and outcomes of vascular complications observed after PNL. Material and methods: We retrospectively reviewed data on 19 patients who underwent renal embolization due to post-PNL renal artery bleeding between March 2005 and September 2016...
December 2017: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/29357554/re-effectiveness-of-treatment-modalities-on-kidney-stone-recurrence
#20
Dean G Assimos
No abstract text is available yet for this article.
February 2018: Journal of Urology
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