keyword
MENU ▼
Read by QxMD icon Read
search

Lama

keyword
https://www.readbyqxmd.com/read/28426357/a-qualitative-assessment-of-alcohol-consumption-and-sexual-risk-behaviors-among-men-who-have-sex-with-men-and-transgender-women-in-peru
#1
Panagiotis Vagenas, Shan-Estelle Brown, Jesse L Clark, Kelika A Konda, Javier R Lama, Jorge Sánchez, Ann C Duerr, Frederick L Altice
BACKGROUND: Peruvian men who have sex with men (MSM) and transgender women (TGW) experience the double burden of a highly concentrated HIV epidemic with a high prevalence of alcohol use disorders (AUDs). Recent research has associated both with risky sexual behaviors, including unprotected sex, having multiple sexual partners, engaging in sex work, having recent sexually transmitted infections, and having HIV-infected partners. AUDs have also been associated in MSM/TGW with being unaware of HIV+ status...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28421354/perceived-barriers-and-facilitators-to-integrating-hiv-prevention-and-treatment-with-cross-sex-hormone-therapy-for-transgender-women-in-lima-peru
#2
Sari L Reisner, Amaya G Perez-Brumer, Sarah A McLean, Javier R Lama, Alfonso Silva-Santisteban, Leyla Huerta, Jorge Sanchez, Jesse L Clark, Matthew J Mimiaga, Kenneth H Mayer
Transgender women (TW) represent a vulnerable population at increased risk for HIV infection in Peru. A mixed-methods study with 48 TW and 19 healthcare professionals was conducted between January and February 2015 to explore barriers and facilitators to implementing a model of care that integrates HIV services with gender-affirmative medical care (i.e., hormone therapy) in Lima, Peru. Perceived acceptability of the integrated care model was high among TW and healthcare professionals alike. Barriers included stigma, lack of provider training or Peruvian guidelines regarding optimal TW care, and service delivery obstacles (e...
April 18, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28420401/using-media-to-impact-health-policy-making-an-integrative-systematic-review
#3
REVIEW
Lama Bou-Karroum, Fadi El-Jardali, Nour Hemadi, Yasmine Faraj, Utkarsh Ojha, Maher Shahrour, Andrea Darzi, Maha Ali, Carine Doumit, Etienne V Langlois, Jad Melki, Gladys Honein AbouHaidar, Elie A Akl
INTRODUCTION: Media interventions can potentially play a major role in influencing health policies. This integrative systematic review aimed to assess the effects of planned media interventions-including social media-on the health policy-making process. METHODS: Eligible study designs included randomized and non-randomized designs, economic studies, process evaluation studies, stakeholder analyses, qualitative methods, and case studies. We electronically searched Medline, EMBASE, Communication and Mass Media Complete, Cochrane Central Register of Controlled Trials, and the WHO Global Health Library...
April 18, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28416805/a-new-inhibitor-of-the-%C3%AE-arrestin-ap2-endocytic-complex-reveals-interplay-between-gpcr-internalization-and-signalling
#4
Alexandre Beautrait, Justine S Paradis, Brandon Zimmerman, Jenna Giubilaro, Ljiljana Nikolajev, Sylvain Armando, Hiroyuki Kobayashi, Lama Yamani, Yoon Namkung, Franziska M Heydenreich, Etienne Khoury, Martin Audet, Philippe P Roux, Dmitry B Veprintsev, Stéphane A Laporte, Michel Bouvier
In addition to G protein-coupled receptor (GPCR) desensitization and endocytosis, β-arrestin recruitment to ligand-stimulated GPCRs promotes non-canonical signalling cascades. Distinguishing the respective contributions of β-arrestin recruitment to the receptor and β-arrestin-promoted endocytosis in propagating receptor signalling has been limited by the lack of selective analytical tools. Here, using a combination of virtual screening and cell-based assays, we have identified a small molecule that selectively inhibits the interaction between β-arrestin and the β2-adaptin subunit of the clathrin adaptor protein AP2 without interfering with the formation of receptor/β-arrestin complexes...
April 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/28416411/awake-high-flow-extracranial-to-intracranial-hfec-ic-bypass-for-complex-cerebral-aneurysms-institutional-clinical-trial-results
#5
Saleem I Abdulrauf, Jorge F Urquiaga, Ritesh Patel, J Andrew Albers, Sirajeddin Belkhair, Kyle Dryden, Michael Prim, Douglas Snyder, Brian Kang, Lama Mokhlis, Asad S Akhter, Lauren N Mackie, Abdullah Alatar, Elizabeth A Erickson, Nanthiya Sujijantarat, Jay Shah, Trenton Wecker, George Stevens, Jodi Walsh, Abigail Schweiger, Paula Buchanan
No abstract text is available yet for this article.
April 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28414695/imaging-criteria-to-predict-surgical-difficulties-during-stapes-surgery
#6
Claire Parra, Stéphanie Trunet, Benjamin Granger, Yann Nguyen, Georges Lamas, Daniele Bernardeschi, Rémi Hervochon, Frédéric Tankere
BACKGROUND AND PURPOSE: Stapes surgery for otosclerosis can be challenging if access to the oval window niche is restricted. The aim of this study was to determine the accuracy of the computed tomographic (CT) scan in the evaluation of anatomical distances, and to analyze its reliability in predicting surgical technical difficulties. MATERIAL AND METHODS: A total of 96 patients (101 ears) were enrolled in a prospective study between 2012 and May 2015. During surgery, we evaluated the distance D1 between the stapes and the facial nerve, distance D2 between the promontory and the facial nerve after ablation of the superstructure, and the intraoperative discomfort of the surgeon...
April 13, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28413612/advances-in-understanding-the-renin-angiotensin-aldosterone-system-raas-in-blood-pressure-control-and-recent-pivotal-trials-of-raas-blockade-in-heart-failure-and-diabetic-nephropathy
#7
REVIEW
Lama Ghazi, Paul Drawz
The renin-angiotensin-aldosterone system (RAAS) plays a fundamental role in the physiology of blood pressure control and the pathophysiology of hypertension (HTN) with effects on vascular tone, sodium retention, oxidative stress, fibrosis, sympathetic tone, and inflammation. Fortunately, RAAS blocking agents have been available to treat HTN since the 1970s and newer medications are being developed. In this review, we will (1) examine new anti-hypertensive medications affecting the RAAS, (2) evaluate recent studies that help provide a better understanding of which patients may be more likely to benefit from RAAS blockade, and (3) review three recent pivotal randomized trials that involve newer RAAS blocking agents and inform clinical practice...
2017: F1000Research
https://www.readbyqxmd.com/read/28411568/projecting-biodiversity-and-wood-production-in-future-forest-landscapes-15-key-modeling-considerations
#8
Adam Felton, Thomas Ranius, Jean-Michel Roberge, Karin Öhman, Tomas Lämås, Jari Hynynen, Artti Juutinen, Mikko Mönkkönen, Urban Nilsson, Tomas Lundmark, Annika Nordin
A variety of modeling approaches can be used to project the future development of forest systems, and help to assess the implications of different management alternatives for biodiversity and ecosystem services. This diversity of approaches does however present both an opportunity and an obstacle for those trying to decide which modeling technique to apply, and interpreting the management implications of model output. Furthermore, the breadth of issues relevant to addressing key questions related to forest ecology, conservation biology, silviculture, economics, requires insights stemming from a number of distinct scientific disciplines...
April 12, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28410560/role-of-long-acting-muscarinic-antagonist-long-acting-%C3%AE-2-agonist-therapy-in-chronic-obstructive-pulmonary-disease
#9
Sarah E Petite
OBJECTIVE: To compare the available literature regarding the use of long-acting muscarinic antagonist (LAMA)/long-acting β2 agonists (LABA) and inhaled corticosteroid (ICS)/LABA combination inhaler therapy in chronic obstructive pulmonary disease (COPD) maintenance therapy management. DATA SOURCES: A MEDLINE literature search from database inception to February 2017 was conducted using the search terms chronic obstructive pulmonary disease, adrenergic beta-agonist, muscarinic antagonist, and inhaled corticosteroid...
April 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28410408/pleistocene-climate-changes-shaped-the-population-structure-of-partamona-seridoensis-apidae-meliponini-an-endemic-stingless-bee-from-the-neotropical-dry-forest
#10
Elder Assis Miranda, Kátia Maria Ferreira, Airton Torres Carvalho, Celso Feitosa Martins, Carlo Rivero Fernandes, Marco Antonio Del Lama
Partamona seridoensis is an endemic stingless bee from the Caatinga, a Neotropical dry forest in northeastern Brazil. Like other stingless bees, this species plays an important ecological role as a pollinator. The aim of the present study was to investigate the genetic structure and evolutionary history of P. seridoensis across its current geographic range. Workers from 84 nests from 17 localities were analyzed for COI and Cytb genic regions. The population structure tests (Bayesian phylogenetic inference, AMOVA and haplotype network) consistently characterized two haplogroups (northwestern and eastern), with little gene flow between them, generating a high differentiation between them as well as among the populations within each haplogroup...
2017: PloS One
https://www.readbyqxmd.com/read/28409723/role-of-electrophysiology-in-guiding-near-total-resection-for-preservation-of-facial-nerve-function-in-the-surgical-treatment-of-large-vestibular-schwannomas
#11
Daniele Bernardeschi, Nadya Pyatigorskaya, Antoine Vanier, Franck Bielle, Mustapha Smail, Georges Lamas, Olivier Sterkers, Michel Kalamarides
OBJECTIVE In large vestibular schwannoma (VS) surgery, the facial nerve (FN) is at high risk of injury. Near-total resection has been advocated in the case of difficult facial nerve dissection, but the amount of residual tumor that should be left and when dissection should be stopped remain controversial factors. The objective of this study was to report FN outcome and radiological results in patients undergoing near-total VS resection guided by electromyographic supramaximal stimulation of the FN at the brainstem...
April 14, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28408686/permanent-draft-genome-sequence-of-the-french-bean-symbiont-rhizobium-sp-strain-rsm-3-isolated-from-the-eastern-himalayan-region-of-india
#12
Ritu Rai, Erik Swanson, Indrani Sarkar, Dorjay Lama, Feseha Abebe-Aleke, Stephen Simpson, Krystalynne Morris, W Kelley Thomas, Pallab Kar, Maher Gtari, Arnab Sen, Louis S Tisa
The genus Rhizobium contains many species able to form nitrogen-fixing nodules on plants of the legume family. Here, we report the 6.9-Mbp draft genome sequence of Rhizobium sp. strain RSm-3, with a G+C content of 61.4% and 6,511 candidate protein-coding genes.
April 13, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28407648/international-sexual-partnerships-may-be-shaped-by-sexual-histories-and-socioeconomic-status
#13
Hong-Ha M Truong, Megha Mehrotra, Orlando Montoya, Javier R Lama, Juan V Guanira, Martín Casapía, Valdiléa G Veloso, Susan P Buchbinder, Kenneth H Mayer, Suwat Chariyalertsak, Mauro Schechter, Linda-Gail Bekker, Esper G Kallás, Robert M Grant
Exchange sex and higher education were associated with an increased likelihood of international sexual partnerships (ISPs). Exchange sex and older age were associated with an increased likelihood of condomless sex in ISPs. Educational and socioeconomic factors may create unbalanced power dynamics that influence exchange sex and condomless sex in ISPs.
May 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28407435/sl15-a-seminal-plasma-derived-lectin-from-the-sperm-of-llama-lama-glama
#14
Renato Zampini, Sabrina Sequeira, Martin Eduardo Argañaraz, Silvana Andrea Apichela
The oviductal sperm reservoir of South American camelids is formed when sperm bind to N-acetylgalactosamine (GalNAc) on the surface of oviductal epithelium. The aim of this study was to characterize the GalNAc-binding proteins on llama sperm, and to establish their origin. Sperm-adsorbed proteins were extracted with 0.5 M KCl in Hepes-balanced salts. Sperm-adsorbed and seminal plasma proteins were then subjected to ligand blotting for their GalNAc affinity, and the labeled bands were identified by mass spectrometry...
April 13, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/28403549/chaotropic-heat-treatment-resolves-native-like-aggregation-of-a-heterologously-produced-hyperthermostable-laminarinase
#15
Adrie H Westphal, Astrid A Geerke-Volmer, Carlo P M van Mierlo, Willem J H van Berkel
Production of hyperthermostable enzymes in mesophilic hosts frequently causes undesired aggregation of these proteins. During production of Pyrococcus furiosus endo-β-1,3 glucanase (LamA) in Escherichia coli, soluble and insoluble species form. Here, we address the composition of this mixture, including the nature of LamA conformers, and establish a method to increase the yield of native monomer. With gel electrophoresis, size-exclusion chromatography, light scattering, circular dichroism and enzyme kinetics we show that approximately 50 % of heterologously produced LamA is soluble, and that 40 % of this fraction constitutes native-like oligomers and non-native monomers...
April 12, 2017: Biotechnology Journal
https://www.readbyqxmd.com/read/28399855/characterisation-of-a-murine-model-of-the-late-asthmatic-response
#16
Katie Baker, Kristof Raemdonck, Robert J Snelgrove, Maria G Belvisi, Mark A Birrell
BACKGROUND: The incidence of asthma is increasing at an alarming rate. While the current available therapies are effective, there are associated side effects and they fail to adequately control symptoms in all patient subsets. In the search to understand disease pathogenesis and find effective therapies hypotheses are often tested in animal models before progressing into clinical studies. However, current dogma is that animal model data is often not predictive of clinical outcome. One possible reason for this is the end points measured such as antigen-challenge induced late asthmatic response (LAR) is often used in early clinical development, but seldom in animal model systems...
April 11, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28399013/caspase-recruitment-domain-9-microbiota-and-tryptophan-metabolism-dangerous-liaisons-in-inflammatory-bowel-diseases
#17
Bruno Lamas, Mathias L Richard, Harry Sokol
PURPOSE OF REVIEW: Inflammatory bowel diseases (IBDs) develop as a result of a combination of genetic predisposition, dysbiosis of the gut microbiota, and environmental influences. Here, we describe an example of how caspase recruitment domain 9 (CARD9), one of the numerous IBD susceptibility genes, participate to colitis susceptibility by shaping gut microbiota to produce tryptophan metabolites. RECENT FINDINGS: Recent study showed that CARD9 mice are more susceptible to colitis as a result of impaired interleukin 22 signaling pathway...
April 8, 2017: Current Opinion in Clinical Nutrition and Metabolic Care
https://www.readbyqxmd.com/read/28395575/safety-of-inhaled-long-acting-anti-muscarinic-agents-in-copd
#18
Nicola A Hanania, Suzanne C Lareau, Barbara P Yawn
Evidence-based guidelines recommend inhaled long-acting anti-muscarinic agents (LAMAs) as first-line maintenance therapy for symptomatic patients with COPD. Several LAMAs are now available for use either as monotherapy or in combination with other COPD medications, including long-acting β2-agonists (LABAs) or inhaled corticosteroids (ICS). The efficacy and long-term safety of these medications have been evaluated in multiple clinical trials and real-life studies. This review evaluates the evidence available on the safety of existing LAMAs alone or in combination with LABAs and ICS in patients with COPD...
April 20, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28395252/a-glucose-sensitive-block-glycopolymer-hydrogel-based-on-dynamic-boronic-ester-bonds-for-insulin-delivery
#19
Baoqi Cai, Yanping Luo, Qianqian Guo, Xinge Zhang, Zhongming Wu
Hydrogels are good candidates to satisfy many needs for functional and tunable biomaterials. How to precisely control the gel structure and functions is crucial for the construction of sophisticated soft biomaterials comprising the hydrogels, which facilitates the impact of the surrounding environment on a unique biological function occurring. Here, glucose-responsive hydrogels comprised of 3-acrylamidophenyl boronic acid copolymerized with 2-lactobionamidoethyl methacrylate (p(APBA-b-LAMA)) were synthesized, and further evaluated as carriers for insulin delivery...
April 6, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28392684/cost-effectiveness-analysis-of-umeclidinium-vilanterol-for-the-management-of-patients-with-moderate-to-very-severe-copd-using-an-economic-model
#20
Michele R Wilson, Jeetvan G Patel, Amber Coleman, Cheryl L McDade, Richard H Stanford, Stephanie R Earnshaw
BACKGROUND: Bronchodilators such as long-acting muscarinic antagonists (LAMAs) and long-acting β2-agonists (LABAs) are central to the pharmacological management of COPD. Dual bronchodilation with umeclidinium/vilanterol (UMEC/VI; 62.5/25 μg) is a novel LAMA/LABA combination approved for maintenance treatment for patients with COPD. OBJECTIVE: The objective of this study was to assess the cost-effectiveness of maintenance treatment with UMEC/VI compared with tiotropium (TIO) 18 μg, open dual LAMA + LABA treatment, or no long-acting bronchodilator treatment in patients with moderate to very severe COPD...
2017: International Journal of Chronic Obstructive Pulmonary Disease
keyword
keyword
8892
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"