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https://www.readbyqxmd.com/read/28535423/chromatographic-separation-and-detection-methods-of-aloe-arborescens-miller-constituents-a-systematic-review
#1
REVIEW
Jilan A Nazeam, Haidy A Gad, Hala M El-Hefnawy, Abdel-Naser B Singab
Aloe arborescens Miller (Family Asphodelaceae) is a member of genus Aloe, which is used in traditional medicine to cure various diseases. The extracts of the plant have been reported to possess anticancer, immunomodulator, antidiabetic, anti-inflammatory and antioxidant activities. The phytochemical investigations have revealed diverse chemical constituents, including phenolics [anthraquinones, anthrones, pyrones, chromones and coumarins], polysaccharides [arborans [(1-4) linked glucomannans, polysaccharide (A, B and C): (A: a linear (1-6)-O-α-glucan, B: a branching (1-2)-O-l-arabinose with (1-2)-O-d-galactose linkages and C: (1-4)-O-β-mannan with 18% acetyl group)]], glycoproteins and carboxypeptidase enzyme...
April 29, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28535320/effectiveness-of-a-labor-cervical-exam-model-in-family-medicine-and-ob-gyn-residents
#2
Joshua F Nitsche, Nora F Fino, Jose M Palomo, Abraham Portillo Perdomo, Brian C Brost
BACKGROUND AND OBJECTIVES: Labor cervical exam accuracy is an essential skill for family medicine and OB-GYN residents to master. To determine the effectiveness of simulation on labor cervical exam training, family medicine and OB-GYN residents were trained using a self-constructed PVC pipe-based cervical exam model during a short and intensive simulation workshop or "boot camp." METHODS: A task trainer was constructed that allows for the blind examination of cervical dilation and effacement...
May 2017: Family Medicine
https://www.readbyqxmd.com/read/28535207/antheraea-pernyi-lepidoptera-saturniidae-and-its-importance-in-sericulture-food-consumption-and-traditional-chinese-medicine
#3
Wenli Li, Zhengyao Zhang, Lan Lin, Olle Terenius
Sericulture was developed in China in ancient times. Antheraea pernyi Guérin-Méneville was domesticated at least 2,000 yr ago, and Chinese farmers developed artificial rearing of A. pernyi before the 17th century. Today, >60,000 tons of cocoons are produced in China each year, which accounts for 90% of the world production. Despite the widespread utilization of A. pernyi in China and a long history of domestic research, the knowledge of A. pernyi outside China is limited. Therefore, we have in this paper summarized the production, usage, and breeding of A...
May 23, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28534943/bu-fei-decoction-attenuates-the-tumor-associated-macrophage-stimulated-proliferation-migration-invasion-and-immunosuppression-of-non-small-cell-lung-cancer-partially-via-il-10-and-pd-l1-regulation
#4
Lina Pang, Shuyan Han, Yanna Jiao, Shantong Jiang, Xiran He, Pingping Li
Macrophages play a pivotal role in tumor microenvironment. Bu-Fei Decoction (BFD) is a classical formula of traditional Chinese medicine (TCM) to alleviate lung cancer related symptoms, whether it has antitumor effect or could influence cancer microenvironment deserves further study. The aim of the present study was to examine the antitumor effect of BFD on non-small cell lung cancer (NSCLC), and to investigate the underlying mechanisms through tumor associated macrophages (TAMs). M2-polarized TAMs were induced by Phorbol 12-myristate 13-acetate (PMA) and interleukin 4 (IL-4)...
May 19, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28534835/emulsion-based-intradermal-delivery-of-melittin-in-rats
#5
Sang Mi Han, Se Gun Kim, Sok Cheon Pak
Bee venom (BV) has long been used as a traditional medicine. The aim of the present study was to formulate a BV emulsion with good rheological properties for dermal application and investigate the effect of formulation on the permeation of melittin through dermatomed rat skin. A formulated emulsion containing 1% (w/v) BV was prepared. The emulsion was compared with distilled water (DW) and 25% (w/v) N-methyl-2-pyrrolidone (NMP) in DW. Permeation of melittin from aqueous solution through the dermatomed murine skin was evaluated using the Franz diffusion cells...
May 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28534819/ginsenoside-rb2-alleviates-hepatic-lipid-accumulation-by-restoring-autophagy-via-induction-of-sirt1-and-activation-of-ampk
#6
Qi Huang, Ting Wang, Liu Yang, He-Yao Wang
Although Panax ginseng is a famous traditional Chinese medicine and has been widely used to treat a variety of metabolic diseases including hyperglycemia, hyperlipidemia, and hepatosteatosis, the effective mediators and molecular mechanisms remain largely unknown. In this study we found that ginsenoside Rb2, one of the major ginsenosides in Panax ginseng, was able to prevent hepatic lipid accumulation through autophagy induction both in vivo and in vitro. Treatment of male db/db mice with Rb2 significantly improved glucose tolerance, decreased hepatic lipid accumulation, and restored hepatic autophagy...
May 19, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28534695/wound-healing-activity-of-pluchea-indica-leaf-extract-in-oral-mucosal-cell-line-and-oral-spray-formulation-containing-nanoparticles-of-the-extract
#7
Wiphupat Buranasukhon, Sirivan Athikomkulchai, Sarin Tadtong, Chuda Chittasupho
CONTEXT: Pluchea indica (L.) Less (Asteraceae) is an herb used as a traditional medicine for wound healing. The chemical compounds found in Pluchea indica leaves are phenolic acids, flavonoids, anthocyanins and carotenoids. OBJECTIVE: This study investigates the effect of Pluchea indica leaf ethanol extract and its nanoparticles (NPs) on cytotoxicity, cell survival and migration of human oral squamous carcinoma cell line. MATERIALS AND METHODS: Cell viability was measured using MTT assay to assess the effect of Pluchea indica leaf extract and NPs (1-500 μg/mL) on cytotoxicity and cell survival...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28534425/evaluation-of-berberine-as-a-natural-fungicide-biodegradation-and-antimicrobial-mechanism
#8
Ying Li, Yi-Ming Yin, Xin-Yue Wang, Hao Wu, Xi-Zhen Ge
Berberine (BBR) is a traditional Chinese medicine which recently was applied as a biological pesticide. Here, we studied the antimicrobial mode of BBR and its impact on soil bacterial diversity. BBR was more effective against fungi than bacteria due to the specific interaction between BBR and glucan. Also, BBR was degraded rapidly in soil, leading to the limited effect on soil bacterial diversity. Collectively, BBR is an environment-friendly pesticide and it is promising in dealing with fungal plant diseases...
May 23, 2017: Journal of Asian Natural Products Research
https://www.readbyqxmd.com/read/28534383/in-vitro-anticancer-activity-and-cytotoxicity-screening-of-phytochemical-extracts-from-selected-traditional-chinese-medicinal-plants
#9
Chao Liang, Hui Pan, Haizhou Li, Yang Zhao, Yang Feng
PURPOSE: The purpose of this study was to evaluate the anticancer activity of 10 selected traditional Chinese medicinal plants on 4 cancer cell lines, namely MCF-7 (breast carcinoma), BALL-1 (acute lymphoblastic leukemia), Huh-7 (hepatocellular carcinoma), HeLa (cervical carcinoma) and their cytotoxicity on a normal cell line, namely MCF-10A (non-tumorigenic mammary epithelial line), about which there were few reports previously. METHODS: Six phytochemical extracts, namely petroleum ether extract (PEE), chloroform extract (CE), ethyl acetate extract (EAE), n-butanol extract (BE), the remainder after extraction (RE) and water extract (WE) from each plant were prepared...
March 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28533961/transcriptome-analyses-provide-insights-into-the-difference-of-alkaloids-biosynthesis-in-the-chinese-goldthread-coptis-chinensis-franch-from-different-biotopes
#10
Hanting Chen, Cao Deng, Hu Nie, Gang Fan, Yang He
Coptis chinensis Franch., the Chinese goldthread ('Weilian' in Chinese), one of the most important medicinal plants from the family Ranunculaceae, and its rhizome has been widely used in Traditional Chinese Medicine for centuries. Here, we analyzed the chemical components and the transcriptome of the Chinese goldthread from three biotopes, including Zhenping, Zunyi and Shizhu. We built comprehensive, high-quality de novo transcriptome assemblies of the Chinese goldthread from short-read RNA-Sequencing data, obtaining 155,710 transcripts and 56,071 unigenes...
2017: PeerJ
https://www.readbyqxmd.com/read/28533545/treatment-effects-of-the-traditional-chinese-medicine-shenks-in-bleomycin-induced-lung-fibrosis-through-regulation-of-tgf-beta-smad3-signaling-and-oxidative-stress
#11
Haiyan Chu, Ying Shi, Shuai Jiang, Qicheng Zhong, Yongqiang Zhao, Qingmei Liu, Yanyun Ma, Xiangguang Shi, Weifeng Ding, Xiaodong Zhou, Jimin Cui, Li Jin, Gang Guo, Jiucun Wang
Pulmonary fibrosis is a kind of devastating interstitial lung disease due to the limited therapeutic strategies. Traditional Chinese medicine (TCM) practices have put forth Shenks as a promising treatment approach. Here, we performed in vivo study and in vitro study to delineate the anti-fibrotic mechanisms behind Shenks treatment for pulmonary fibrosis. We found that regardless of the prophylactic or therapeutic treatment, Shenks was able to attenuate BLM-induced-fibrosis in mice, down regulate extracellular matrix genes expression, and reduce collagen production...
May 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28532683/the-essential-oil-from-the-twigs-of-cinnamomum-cassia-presl-inhibits-oxytocin-induced-uterine-contraction-in-vitro-and-in-vivo
#12
Lan Sun, Li-Na Liu, Jia-Chun Li, Yao-Zhong Lv, Shao-Bo Zong, Jun Zhou, Zheng-Zhong Wang, Jun-Ping Kou, Wei Xiao
ETHNOPHARMACOLOGICAL RELEVANCE: The twigs and bark of Cinnamomum cassia Presl (Lauraceae) are widely used in traditional Chinese medicine in the treatment of tumor, abdominal pain, dysmenorrhea, digestive system disease and inflammatory diseases. The aim of this study was to determine the inhibitory effect of the essential oil from the twigs of Cinnamomum cassia Presl (EOCC) on uterine contraction in vitro and in vivo. MATERIALS AND METHODS: The Institute of Cancer Research (ICR) mouse uterine contraction was induced by oxytocin (OT) exposure following estradiol benzoate pretreatment...
May 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28532554/traditional-medicines-and-kidney-disease-in-low-and-middle-income-countries-opportunities-and-challenges
#13
REVIEW
John W Stanifer, Kajiru Kilonzo, Daphne Wang, Guobin Su, Wei Mao, Lei Zhang, La Zhang, Shobhana Nayak-Rao, J Jaime Miranda
Traditional medicines are a principal form of health care for many populations, particularly in low- and middle-income countries, and they have gained attention as an important means of health care coverage globally. In the context of kidney diseases, the challenges and opportunities presented by traditional medicine practices are among the most important considerations for developing effective and sustainable public health strategies. However, little is known about the practices of traditional medicines in relation to kidney diseases, especially concerning benefits and harms...
May 2017: Seminars in Nephrology
https://www.readbyqxmd.com/read/28532553/the-potential-impact-of-public-health-interventions-in-preventing-kidney-disease
#14
REVIEW
Rohina Joshi, Oommen John, Vivekanand Jha
The years of life lost and years lived with disability resulting from chronic kidney disease (CKD) increased globally by 90% and 49.5%, respectively, between 1990 and 2013. In addition to the traditional factors, infections, low birthweight, environmental factors, and low socioeconomic status contribute to the CKD burden in low- and middle-income countries. System-level challenges such as poor appreciation of the burden, insufficient human resources, high health care costs, poor referral pathways, unreliable health information systems, and inadequate medicine supply pose barriers to CKD control...
May 2017: Seminars in Nephrology
https://www.readbyqxmd.com/read/28532415/hemodynamic-changes-caused-by-acupuncture-in-healthy-volunteers-a-prospective-single-arm-exploratory-clinical-study
#15
Tae-Hun Kim, Boncho Ku, Jang-Han Bae, Jae-Young Shin, Min-Ho Jun, Jung Won Kang, Junghwan Kim, Jun-Hwan Lee, Jaeuk U Kim
BACKGROUND: Radial pressure pulse wave (RPPW) examination has been a key diagnostic component of traditional Chinese medicine. The objective of this study was to investigate the changes in RPPW along with various hemodynamic variables after acupuncture stimulation and to examine the validity of pulse diagnosis as a modern diagnostic tool. METHODS: We conducted acupuncture stimulation at both ST36 acupuncture points in 25 healthy volunteers. We simultaneously assessed the RPPW by pulse tonometry; heart rate variability (HRV) by electrocardiogram; photoplethysmogram (PPG) signals, respiration rate, peripheral blood flow velocity and arterial depth by ultrasonography; and cardiac output by impedance cardiography, before, during and after a session of acupuncture stimulation...
May 22, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28532071/in-vitro-antibacterial-and-cytotoxic-activities-of-plasma-modified-polyethylene-terephthalate-nonwoven-dressing-with-aqueous-extract-of-rhizome-atractylodes-macrocephala
#16
Yi-Ting Shu, Kuo-Ting Kao, Ching-Sung Weng
In this study, a natural and non-cytotoxic antibacterial dressing containing aqueous extract of Rhizome Atractylodes macrocephala (RAM), which has been widely used in traditional herbal medicine and documented with antibacterial activities in literatures, was developed by aid of the extraction technique, nonwoven substrates and plasma-induced grafting technology. The effectiveness of these herbal antibacterial dressings with different treatment were investigated through the assays of grafting yield, SEM, FTIR, antibacterial activities and cytotoxicity...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28531919/bupleurum-chinense-extract-ameliorates-an-ova-induced-murine-allergic-asthma-through-the-reduction-of-the-th2-and-th17-cytokines-production-by-inactivation-of-nf%C3%AE%C2%BAb-pathway
#17
Thi Tho Bui, Chun Hua Piao, Chang Ho Song, Hee Soon Shin, Ok Hee Chai
Bupleurum chinense belongs to the Bupleurum spp. family that has been used in traditional herbal medicine for over thousand years. It has been reported to have anti-inflammatory, anti-oxidant, hepato-protective, antipyretic, analgesic, anti-fibrotic and immunomodulatory effect. However, the effect of B. Chinense on allergic asthma remains unclear. This study investigated the immunomodulatory effects of B. Chinense extracts (BCE) on airway inflammation in asthmatic mice model. In the ovalbumin (OVA)-induced allergic asthma model, we evaluated the number of total cells, differential inflammatory cells and the production of proinflammatory cytokines in bronchoalveolar lavage fluid (BALF) and lung homogenate as well as histological structure...
May 16, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28530054/-traditional-chinese-medicine-in-treatment-of-atopic-dermatitis
#18
Orit Schachter, David Perla, Shoshana Greenberger, Aviv Barzilai, Sharon Baum
BACKGROUND: Atopic dermatitis is a common chronic inflammatory skin disease, affecting up to 15-30% of children in industrialized countries. As there is no definitive cure for atopic dermatitis, patients often seek other complementary therapeutic options, such as traditional Chinese medicine (TCM). TCM comprises numerous treatment modalities for the management of atopic dermatitis including acupuncture and herbal medicine. We report a case of a two and a half year old child with atopic dermatitis exacerbation treated successfully with TCM...
October 2016: Harefuah
https://www.readbyqxmd.com/read/28529748/local-modulated-electro-hyperthermia-in-combination-with-traditional-chinese-medicine-vs-intraperitoneal-chemoinfusion-for-the-treatment-of-peritoneal-carcinomatosis-with-malignant-ascites-a-phase-ii-randomized-trial
#19
Clifford L K Pang, Xinting Zhang, Zhen Wang, Junwen Ou, Yimin Lu, Pengfei Chen, Changlin Zhao, Xiaopu Wang, Hongyu Zhang, Sergey V Roussakow
The purpose of this study was to develop a safe and non-toxic alternative to the conventional conservative treatment of peritoneal carcinomatosis with malignant ascites (PCMA) by investigating the efficacy and safety of local modulated electro-hyperthermia (mEHT) combined with the traditional Chinese medicine (TCM) 'Shi Pi' herbal decoction, compared with standard intraperitoneal chemoinfusion (IPCI). A randomized, controlled, single-center, open-label clinical trial (phase II) with two parallel groups (allocation ratio, 1:1) was conducted to investigate the efficacy and safety of mEHT+TCM (study group, SG) vs...
May 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28529575/japanese-kampo-medicine-ninjin-yoeito-synergistically-enhances-tumor-vaccine-effects-mediated-by-cd8-t-cells
#20
Shun Takaku, Masumi Shimizu, Hidemi Takahashi
Although Japanese traditional herbal medicine (Kampo) has been widely applied to the treatment of various diseases, including cancer, their mechanisms of action have not yet been elucidated in detail, particularly regarding their role in tumor immunology. The present study investigated the antitumor effects of the Japanese Kampo medicine, ninjin'yoeito (NYT; Ren-Shen-Yang-Rong-Tang in Chinese), which was orally administered with or without an irradiated tumor cell vaccine to a subcutaneous CT26 colon carcinoma tumor model...
May 2017: Oncology Letters
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