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https://www.readbyqxmd.com/read/28435094/diammonium-glycyrrhizinate-alleviates-hepatopulmonary-syndrome-via-restoring-superoxide-dismutase-3-activity-in-rats
#1
Xin Zhao, Jinyu Liu, Shijun Yang, Chen Chen, He Yin, Ting Li, Qiuting Wang, Xiaoya Li, Yulin Lin, Dayong Cai
Hepatopulmonary syndrome (HPS) has a fatal hypoxemia from pulmonary shunts. Superoxide dismutase 3 (SOD3) deficiency involves in this pathogenesis. The purpose of this study was to investigate the underlying mechanisms of diammonium glycyrrhizinate (DG) on HPS via SOD3. Carbon tetrachloride induced HPS rats were treated with captopril or DG for 56 days. Blood gas, pulmonary artery pressures, and histological changes were measured. Molecule dynamics of inducible (iNOS), endothelial (eNOS), neuronal nitric oxide synthase (nNOS) and SOD3 were assessed by immunohistochemistry, quantitative RT-PCR and western blot...
April 20, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28409326/effect-of-corticision-on-orthodontic-tooth-movement-in-a-rat-model-as-assessed-by-rna-sequencing
#2
Qihui Gu, Shuyu Guo, Dongyue Wang, Tingting Zhou, Lin Wang, Zhendong Wang, Junqing Ma
Corticision is a common technique to accelerate orthodontic tooth movement; however, not much is known about the underlying mechanisms. In this study, we investigated the mechanism of alveolar tissue remodeling after corticision in a rat model of tooth movement (TM) by analyzing the differential transcriptome. A total of 36 male rats were equally divided into TM and TM with corticision (TM+C) groups. Alveolar bone response was examined using micro-computed tomography (micro-CT). Osteoclasts and osteoblasts were quantified on tartrate-resistant acid phosphatase (TRAP) and Goldner's trichrome staining...
April 13, 2017: Journal of Molecular Histology
https://www.readbyqxmd.com/read/28400274/characterization-of-gnrh-gnih-elements-in-the-olfacto-retinal-system-and-ovary-during-zebrafish-ovarian-maturation
#3
Sheryll Corchuelo, Emanuel R M Martinez, Arno J Butzge, Lucas B Doretto, Tanda N Valentin, Laura S O Nakaghi, Gustavo M Somoza, Rafael H Nóbrega
Gonadotropin releasing hormone (GnRH) is one of the key players of brain-pituitary-gonad axis, exerting overall control over vertebrate reproduction. In zebrafish, two variants were characterized and name as Gnrh2 and Gnrh3. In this species, Gnrh3, the hypohysiotropic form, is expressed by neurons of the olfactory-retinal system, where it is related with food detection, intra/interspecific recognition, visual acuity and retinal processing modulation. Previous studies have reported the presence of Gnrh receptors in the zebrafish retina, but not yet in the zebrafish olfactory epithelium...
April 8, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28382281/predictive-and-prognostic-biomarkers-of-respiratory-diseases-due-to-particulate-matter-exposure
#4
REVIEW
Hyo Jeong Kim, Min Gi Choi, Moo Kyun Park, Young Rok Seo
Air pollution is getting severe and concerns about its toxicity effects on airway and lung disease are also increasing. Particulate matter (PM) is major component of air pollutant. It causes respiratory diseases, such as asthma, chronic obstructive pulmonary disease, lung cancer, and so on. PM particles enter the airway and lung by inhalation, causing damages to them. Especially, PM2.5 can penetrate into the alveolus and pass to the systemic circulation. It can affect the cardiopulmonary system and cause cardiopulmonary disorders...
March 2017: Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28377114/uptake-and-selective-partitioning-of-dietary-lipids-to-ovarian-and-muscle-tissue-of-maturing-female-coho-salmon-oncorhynchus-kisutch-during-secondary-oocyte-growth
#5
Ronald B Johnson, Eric L Kroeger, William L Reichert, Cameron S Carter, Michael B Rust
Female coho salmon, Oncorhynchus kisutch, were fed one of two experimental feeds containing lipids with markedly different stable (13)C isotope signatures during the late cortical alveolus, lipid droplet, and vitellogenesis stages of secondary oocyte growth. Ovarian and muscle lipids fatty acid concentrations were significantly affected by treatment during all three stages of development. Stable (13)C isotope analyses confirmed that dietary lipids were incorporated into both ovarian and muscle lipids during all three stages and revealed that ovarian lipids were more affected than muscle lipids during vitellogenesis...
April 1, 2017: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/28363864/alveolar-septal-patterning-during-compensatory-lung-growth-part-ii-the-effect-of-parenchymal-pressure-gradients
#6
Shimon Haber, Michal Weisbord, Steven J Mentzer, Akira Tsuda
In most mammals, compensatory lung growth occurs after the removal of one lung (pneumonectomy). Although the mechanism of alveolar growth is unknown, the patterning of complex alveolar geometry over organ-sized length scales is a central question in regenerative lung biology. Because shear forces appear capable of signaling the differentiation of important cells involved in neoalveolarization (fibroblasts and myofibroblasts), interstitial fluid mechanics provide a potential mechanism for the patterning of alveolar growth...
March 28, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28351529/analysis-of-the-regulation-of-surfactant-phosphatidylcholine-metabolism-using-stable-isotopes
#7
REVIEW
Joost Brandsma, Anthony D Postle
The pathways and mechanisms that regulate pulmonary surfactant synthesis, processing, secretion and catabolism have been extensively characterised using classical biochemical and analytical approaches. These have constructed a model, largely in experimental animals, for surfactant phospholipid metabolism in the alveolar epithelial cell whereby phospholipid synthesised on the endoplasmic reticulum is selectively transported to lamellar body storage vesicles, where it is subsequently processed before secretion into the alveolus...
March 25, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/28343157/isolated-unilateral-upper-alveolar-numbness-in-silent-sinus-syndrome
#8
Hung Tuan Lau, Keng Hua Lim
We present a case of a 59-year-old man with left upper alveolar numbness of 2 years' duration in the absence of sinonasal symptoms. On physical examination, he demonstrated mild left facial asymmetry and diminished sensation of his left upper alveolus from the left second upper incisor to first canine. CT imaging revealed chronic sinusitis changes of the left maxillary sinus, with reduced volume and depressed anterior wall. The patient underwent functional endoscopic sinus surgery to re-establish maxillary sinus ventilation...
March 24, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28318163/-the-influence-of-angulation-of-maxillary-anterior-teeth-on-treatment-design-of-dental-implants
#9
Liu Jin, Pu Bishuang, Xia Yulan, Wang Chengze, Wang Gang, Lan Jing
OBJECTIVE: This study aims to analyze the angulation of the maxillary anterior teeth relative to the alveolus to provide reference data for clinicians on the best conditions for implant placement in the esthetic zone. METHODS: Numerous cone beam computed tomography (CBCT) images were reviewed and screened. A total of 150 maxillary images were selected by strict adherence to the defined inclusive criteria, with 75 images each from male and female patients (between the ages of 19 and 48 years at the time of CBCT scan)...
December 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28296982/management-of-extraoral-complications-in-a-patient-treated-with-four-zygomatic-implants
#10
Andrew Dawood, Nicholas Kalavresos
This article details the significant complications associated with treatment of a patient who underwent maxillary reconstruction based entirely on zygomatic implants. The use of zygomatic implants is becoming increasingly widespread, and treatment has been shown to be predictable and generally free of surgical complications. However, extending from the maxillary alveolus, alongside or through the maxillary antrum, toward the zygoma or orbital rim, these long implants have the potential to create a range of complications that may be more serious than those encountered with conventional dental implants...
March 15, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28290310/a-secondary-mandibular-condylar-articulation-and-collateral-effects-on-a-late-neolithic-mandible-from-bois-madame-rockshelter-in-arbre-belgium
#11
Frank L'Engle Williams, Caroline Polet
A Neolithic Belgian mandible from Bois Madame rockshelter in Arbre presents an asymmetrical morphology resulting from a secondary, or false, articulation of the right mandibular condyle. The pathological articulation produced enlarged masseter, medial pterygoid and mylohyoid musculature on the right side as well as a flattening of the right incisal alveolus curvature. The secondary condylar articulation did not lead to pronounced asymmetry of attrition on the antimeres of the dental arcade. This is the most complete mandible from this Late Neolithic collective burial dating to the beginning of the Bronze Age circa 4000 years BP...
March 2017: International Journal of Paleopathology
https://www.readbyqxmd.com/read/28283342/long-term-follow-up-study-of-patients-with-a-unilateral-complete-cleft-of-lip-alveolus-and-palate-following-the-utrecht-treatment-protocol-dental-arch-relationships
#12
Isabelle Francisca Petronella Maria Kappen, Gerhard Koendert Pieter Bittermann, Dirk Bitterman, Aebele Barber Mink van der Molen, William Shaw, Corstiaan Cornelis Breugem
OBJECTIVE: This study sought to evaluate long-term dental arch relationships in adults with a unilateral complete cleft lip and palate (UCLP) treated by the Utrecht protocol and to compare results with the centers from the Eurocleft study. MATERIALS AND METHODS: Retrospective analysis of UCLP patients age 17 or older, treated by two-stage palate closure at the Wilhelmina Children's Hospital, a tertiary center for cleft surgery in Utrecht, the Netherlands. Patients were invited to the clinic for a long-term evaluation...
February 6, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28230590/modified-lateral-surgical-approach-to-the-pterygopalatine-fossa
#13
Masataka Uehara, Masaaki Sasaguri, Shunji Shiiba, Kazuhiro Tominaga
Oral cancer, especially that originates in the maxillary tuberosity, buccal mucosa, and maxillary alveolus, is apt to invade the pterygopalatine fossa, where an intraoral approach is nearly impossible. There are 2 main types of extraoral approach to the pterygopalatine fossa; the anterior approach and the lateral approach. Although the lateral approach has an advantage compared with the anterior approach in terms of cosmetics, after the operation numbness of the lower lip occurs due to the sacrifice of the mental nerve...
February 22, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28210412/reconstruction-of-a-combined-maxillectomy-and-segmental-mandibulectomy-defect-in-a-seven-year-old-with-a-single-free-fibula-osteocutaneous-flap
#14
Shawn T Joseph, Krishnakumar Thankappan, Subramania Iyer
Combined upper alveolectomy and segmental mandibulectomy are complex defects. Reconstruction of these defects is usually suboptimal. We describe the case of a pediatric patient with vessel-depleted neck with recurrent vascular malformation involving the ramus and coronoid process of mandible and a previous history of maxillectomy and a reconstruction with anterolateral thigh flap. The patient underwent wide resection. The defects involving the upper alveolus and mandible were simultaneously reconstructed with a single free fibula flap...
March 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28196170/novel-approach-to-managing-malsequenced-and-malpositioned-immediately-placed-implants-in-the-esthetic-zone
#15
Jacob K Stern, Christopher M Bingham, Brock J Pumphrey, Gerard J Chiche, Eduardo Britton
Esthetic implant therapy can be challenging in the anterior maxilla, and meticulous treatment is often required to deliver optimal esthetics. Close collaboration between surgical and prosthetic team members using the novel approach of prosthetic crown lengthening helped camouflage a shallow implant platform location, providing the proper gingival frame for esthetic restorations. This case report presents an interdisciplinary approach that included ridge augmentation, second-stage crown lengthening, and prosthetic soft tissue manipulation to address an implant placed too shallow in the alveolus of an extraction socket...
March 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28164256/torque-differences-due-to-the-material-variation-of-the-orthodontic-appliance-a-finite-element-study
#16
Spyridon N Papageorgiou, Ludger Keilig, Vaska Vandevska-Radunovic, Theodore Eliades, Christoph Bourauel
BACKGROUND: Torque of the maxillary incisors is crucial to occlusal relationship and esthetics and can be influenced by many factors. The aim of this study was to assess the relative influence of the material of the orthodontic appliance (adhesive, bracket, ligature, and wire) on tooth displacements and developed stresses/strains after torque application. METHODS: A three-dimensional upper right central incisor with its periodontal ligament (PDL) and alveolus was modeled...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28114220/double-anterior-segmental-osteotomy-under-local-anesthesia-for-correcting-adult-protrusion-with-thin-alveolus-and-ankylosed-tooth
#17
Byung-Joon Choi, Baek-Soo Lee, Hee-Jung Lee, Ki-Ho Park, Seong-Hun Kim
BACKGROUNDS: This paper describes an additional benefit in double anterior segmental osteotomy to correct severe anterior protrusion in adult patients with extremely thin mandibular alveolus and ankylosed tooth. For the optimal anterior segmental retraction, an ankylosed posterior tooth needed surgical inclination reposition. During anterior segmental osteotomy surgery under local anesthesia, additional single tooth osteotomy was performed without challenge. METHODS: For anterior segment retraction, osteotomy cuts were made by the surgeon to define a block of bone embedding 6 mandibular anterior teeth...
January 20, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28031106/-protective-effect-of-human-amnion-epithelial-cells-through-endotracheal-instillation-against-lipopolysaccharide-induced-acute-lung-injury-in-mice
#18
Yanmin Xia, Wenchen Wang, Hong Zhang, Jiakuan Chen, Ming Wang, Zhonghu Ge, Jian Wang, Tao Jiang
Objective To investigate the therapeutic effect of human amnion epithelial cells (hAECs) through endotracheal instillation on acute lung injury (ALI) induced by lipopolysaccharide (LPS) in mice and its underlying mechanism. Methods Male C57BL/6 mice were randomly divided into normal control group, hAECs control group, LPS-induced ALI group and hAECs treatment group (n=10 each group). In the latter two groups, mice were subjected to LPS (5 mg/kg) by oral insertion, and 1 hour later, PBS (50 μL) and hAECs (1×10(7)/mL, 50 μL) were administered by oral insertion in the two groups, respectively...
January 2017: Xi Bao Yu Fen Zi Mian Yi Xue za Zhi, Chinese Journal of Cellular and Molecular Immunology
https://www.readbyqxmd.com/read/28028414/goodpasture-syndrome-diagnosed-one-year-and-a-half-after-the-appearance-of-the-first-symptoms-case-report
#19
Jagoda Stojkovikj, Sead Zejnel, Biljana Gerasimovska, Vesna Gerasimovska, Dragana Stojkovic, Martin Trajkovski, Irina Angelovska, Angela Debreslioska, Smilko Jovanovski
BACKGROUND: Goodpasture syndrome was originally described as an association of alveolar haemorrhage and glomerulonephritis. It occurs when the immune system attacks and destroys healthy body tissue. AIM: We are presenting a patient with a clinical picture of pulmonary haemorrhage and glomerulonephritis, which is diagnosed by renal biopsy. CASE PRESENTATION: His illness began a year and a half before being diagnosed. In that period he had occasional exacerbations...
December 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28027239/skoog-primary-periosteoplasty-versus-secondary-alveolar-bone-grafting-in-unilateral-cleft-lip-and-alveolus-long-term-effects-on-alveolar-bone-formation-and-maxillary-growth
#20
Fatima Jabbari, Malin M Hakelius, Andreas L I Thor, Erika A Reiser, Valdemar T Skoog, Daniel J Nowinski
BACKGROUND: Clefts involving the alveolus are treated using one of two strategies: primary periosteoplasty at the time of lip repair or secondary alveolar bone grafting at mixed dentition. Most teams favor secondary alveolar bone grafting because of its high success rate, and concerns have been raised that primary periosteoplasty may interfere with maxillary growth. However, primary periosteoplasty may obviate the need for future bone grafting and is still practiced in some centers. Few studies compare the long-term outcomes of these two strategies...
January 2017: Plastic and Reconstructive Surgery
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