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https://www.readbyqxmd.com/read/29225322/immunohistochemical-study-on-the-secretory-host-defense-system-with-lysozyme-and-secretory-phospholipase-a2-throughout-rat-respiratory-tract
#1
Natsumi Masuda, Youhei Mantani, Chiaki Yoshitomi, Hideto Yuasa, Miho Nishida, Masaya Arai, Junichi Kawano, Toshifumi Yokoyama, Nobuhiko Hoshi, Hiroshi Kitagawa
The host defense system with lysozyme and secretory phospholipase A2 (sPLA2) was immunohistochemically investigated in rat respiratory tract under healthy conditions. In the nasal epithelium, a large number of non-ciliated and non-microvillous cells (NC) and a small number of goblet cells (GC) were immunopositive for lysozyme and sPLA2. A few acinar cells and almost all epithelial cells of intercalated ducts were immunopositive for both bactericidal substances in the nasal glands. In the laryngeal and tracheal epithelia, few NC and GC were immunopositive for both bactericidal substances...
December 8, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29223639/extensive-phenotyping-of-the-orofacial-and-dental-complex-in-crouzon-syndrome
#2
Alexander Khominsky, Robin Yong, Sarbin Ranjitkar, Grant Townsend, Peter J Anderson
OBJECTIVES: Fibroblast growth factor receptor 2 (FGFR2) C342Y/+ mutation is a known cause of Crouzon syndrome that is characterised by craniosynostosis and midfacial hypoplasia. Our aim was to conduct extensive phenotyping of the maxillary, mandibular and dental morphology associated with this mutation. MATERIALS AND METHODS: Morphometric data were obtained from 40 mice, representing two genotypes (Crouzon and wild-type) and two sexes (males and females) (n=10 in each group)...
October 27, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/29223634/the-composite-palatal-island-flap-modification-of-an-existing-technique-to-reconstruct-the-maxillary-alveolus
#3
A Mosea
No abstract text is available yet for this article.
December 6, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29213014/a-case-of-a-giant-mass-in-the-lumbar-region-of-a-newborn-calf
#4
Kazuki Yoshioka, Aika Ishikawa, Makoto Sugiyama, Jun Nagasao, Motohiro Kikuchi
The present report describes a newborn calf with spina bifida that presented with a giant mass of the lumbar region, as well as subsequent gross, histological, and immunohistochemical examinations. A malformed Japanese black calf (estimated weight = 20 kg) was euthanized immediately after birth. A gross evaluation revealed a giant mass (approximately 60 cm × 30 cm × 15 cm) covered by the hair coat in the lumbar region and connected with the hair coat of the trunk. The mass surface was divided by a deep polygonal groove and externally resembled a lobulated kidney...
2017: Okajimas Folia Anatomica Japonica
https://www.readbyqxmd.com/read/29195817/radial-plane-tooth-position-and-bone-wall-dimensions-in-the-anterior-maxilla-a-cbct-classification-for-immediate-implant-placement
#5
Howard Gluckman, Carla Cruvinel Pontes, Jonathan Du Toit
STATEMENT OF PROBLEM: The biological and esthetic challenge of the post-extraction ridge is relevant to restorative implant dentistry, most significantly in the anterior esthetic zone. Previous authors have discussed facial bone wall dimensions and classified their variations. A reclassification may be pertinent. PURPOSE: The purpose of this observational, clinical study was to introduce a new classification system for anterior maxilla tooth position with guidelines for immediate implant placement...
November 29, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29194721/initial-experiences-with-nam-assisted-primary-repair-of-the-bclp-deformity
#6
Sabarinath Prasad, Sreeja Ravindran, Vasanth Radhakrishnan, P V Hazarey, Amit Vanka, Bhavya Rajan
BACKGROUND: Primary surgical repair of the bilateral cleft lip and palate (BCLP) deformity is challenging. Infant Orthopedic (IO) procedures are often used to assist surgical reconstruction of normal anatomy. Nasoalveolar molding (NAM) is a presurgical infant orthopedic procedure that attempts to reduce the cleft nasal deformity, in addition to the lip and alveolus, leading to an esthetic primary surgical repair. OBJECTIVE: NAM provides the surgical team with a better foundation for an easier and more esthetic single stage repair at the level of nose in addition to the lip and alveolus...
December 1, 2017: Special Care in Dentistry
https://www.readbyqxmd.com/read/29192349/placement-of-an-antibiotic-oral-pack-on-the-hard-palate-after-primary-cleft-palatoplasty-a-randomized-controlled-trial-into-the-effect-on-fistula-rates
#7
Rajgopal R Reddy, Srinivas Gosla Reddy, Bhavya Banala, Ewald M Bronkhorst, Ann W Kummer, Anne Marie Kuijpers-Jagtman, Stefaan J Bergé
OBJECTIVE: The objective of this study is to determine whether placement of an antibiotic oral pack on the hard palate reduces fistula rates after primary cleft palatoplasty. SUBJECTS AND METHODS: This study was a parallel blocked randomized controlled trial. The study consisted of two groups of 100 patients each with non-syndromic unilateral complete cleft lip, alveolus, and hard and soft palate that underwent primary palatoplasty. Group A had an oral pack placed on the hard palate for 5 days postoperatively while group B did not...
November 30, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29184405/absence-of-lung-fibrosis-after-a-single-pulmonary-delivery-of-lipid-nanocapsules-in-rats
#8
José Hureaux, Franck Lacoeuille, Frédéric Lagarce, Marie-Christine Rousselet, Aurélien Contini, Patrick Saulnier, Jean-Pierre Benoit, Thierry Urban
Lipid nanocapsules (LNCs) are potential drug carriers for pulmonary delivery since they can be nebulized without any structural or functional changes, and the aerosols produced are highly compatible with pulmonary drug delivery in human beings. The alveolar surface tension, in vitro cytotoxicity, biodistribution and pulmonary toxicity in rats of a single endotracheal spray of LNCs or paclitaxel-loaded LNCs were studied. In vitro cytotoxicity of LNCs after a spray remained unchanged. Biodistribution study showed a homogeneous repartition in the lungs in rats with an improvement in lung retention of the radiolabeled tracer loaded in LNCs compared to the absence of LNCs with a lung half-time of 8...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29175081/epithelial-mesenchymal-crosstalk-influences-cellular-behavior-in-a-3d-alveolus-fibroblast-model-system
#9
Katherine J R Lewis, Jessica K Hall, Emi A Kiyotake, Tova Christensen, Vivek Balasubramaniam, Kristi S Anseth
Interactions between lung epithelium and interstitial fibroblasts are increasingly recognized as playing a major role in the progression of several lung pathologies, including cancer. Three-dimensional in vitro co-culture systems offer tissue-relevant platforms to study the signaling interplay between diseased and healthy cell types. Such systems provide a controlled environment in which to probe the mechanisms involved in epithelial-mesenchymal crosstalk. To recapitulate the native alveolar tissue architecture, we employed a cyst templating technique to culture alveolar epithelial cells on photodegradable microspheres and subsequently encapsulated the cell-laden spheres within poly (ethylene glycol) (PEG) hydrogels containing dispersed pulmonary fibroblasts...
November 15, 2017: Biomaterials
https://www.readbyqxmd.com/read/29157548/imaging-of-benign-odontogenic-lesions
#10
REVIEW
William C Scarfe, Shiva Toghyani, Bruno Azevedo
Numerous benign cysts or solid tumors may present in the jaws. These arise from tooth-forming tissues in the dental alveolus or from nonodontogenic tissues in the basal bone of the mandible and maxilla. Radiologists provide 2 deliverables to assist in diagnosis and management: (1) appropriately formatted images demonstrating the location and extent of the lesion and (2) interpretive reports highlighting specific radiologic findings and an impression providing a radiologic differential diagnosis. This article provides guidance on essential image protocols for planning treatments, a radiologic differential diagnostic algorithm based on location and pattern recognition, and a summary of the main features of benign odontogenic lesions...
January 2018: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/29110549/a-104-week-pulmonary-toxicity-assessment-of-long-and-short-single-wall-carbon-nanotubes-after-a-single-intratracheal-instillation-in-rats
#11
Kazumasa Honda, Masato Naya, Hiroshi Takehara, Hiromichi Kataura, Katsuhide Fujita, Makoto Ema
We compared long-term pulmonary toxicities after a single intratracheal instillation of two types of dispersed single-wall carbon nanotubes (SWCNTs), namely, those with relatively long or short linear shapes with average lengths of 8.6 and 0.55 µm, respectively. Both types of SWCNTs were instilled intratracheally in male F344 rats at 0.2 or 1.0 mg/kg (long SWCNTs) or 1.0 mg/kg (short SWCNTs). Pulmonary responses were characterized at 26, 52 and 104 weeks after a single instillation. Inflammatory changes, test substance deposition, test substance engulfment by macrophages, and alveolar wall fibrosis were observed in the lungs of almost all test rats at 52 and 104 weeks after short nanotube instillation...
November 7, 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/29104383/comparison-of-dermatoglyphic-pattern-among-cleft-and-noncleft-children-a-cross-sectional-study
#12
Sandeep S Mayall, Seema Chaudhary, Harsimran Kaur, Naveen Manuja, Telegi Ravishankar, Ashish A Sinha
Background: Oral clefts are among the common congenital birth defects with a broad phenotypic gamut. Since the epidermal ridges of the fingers and palms as well as the facial structures like lip, alveolus, and palate are formed from the same embryonic tissues during the same embryonic period, the genetic and environmental factors responsible for causing cleft lip and palate might also affect dermatoglyphic patterns. Aim: Thus, study was undertaken to compare the dermato-glyphic pattern of children with orofacial clefts and normal children and to determine the correlation of dermatoglyphics with orofacial clefts...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29068580/orthodontic-intrusion-of-periodontally-compromised-maxillary-incisors-3-dimensional-finite-element-method-analysis
#13
Liwia E Minch, Michał Sarul, Rafał Nowak, Beata Kawala, Joanna Antoszewska-Smith
BACKGROUND: Loading of the compromised periodontium with orthodontic forces produces different results than those achieved in patients with healthy periodontal support. Determining the force value at a level preventing further deterioration of the patient's periodontal status, thus delivering the most precisely individualized "dose" of loading, seems to be crucial for the successful intrusion of teeth with reduced periodontal support. OBJECTIVES: The aim of the study was to determine the range of force values efficiently intruding maxillary incisors without further compromising the initially-impaired periodontal status...
August 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29066039/custom-milled-individual-allogeneic-bone-grafts-for-alveolar-cleft-osteoplasty-a-technical-note
#14
Sven Otto, Christin Kleye, Egon Burian, Michael Ehrenfeld, Carl-Peter Cornelius
INTRODUCTION: Bone grafts from the iliac crest are most commonly used for osteoplasties of the cleft alveolus. To preclude undue donoresite morbidity custom-milled allogeneic bone grafts might be an appropriate choice. MATERIAL AND METHODS: This technical note showcases the repair of an alveolar cleft using an individualized allogeneic bone graft in a 36-year old female patient. She was asking for an alternative to the iliac crest bone grafting. Her alveolus was successfully build up by a custom-milled cancellous bone block allograft (maxgraft(®) 80 bonebuilder)...
September 20, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29065047/corticotomy-with-a-palatal-bone-borne-retractor-for-correcting-severe-bimaxillary-protrusion
#15
Min-Ki Noh, Young-Jun Kim, Kyu-Rhim Chung, Seong-Hun Kim, Gerald Nelson
BACKGROUND: This article presents an alternate surgical treatment method to correct a severe anterior protrusion in the adult patient with an extremely thin alveolus. METHODS: In the maxilla, a wide linear corticotomy was performed under local anesthesia. Cortical alveolar bone of the upper first bicuspids area was widely removed. Orthopedic force for bony block movement was applied by a palatal bone-borne type retractor supported by skeletal anchorage. Residual extraction space closure was performed by biocreative orthodontics strategy (BOS)...
October 23, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29045046/a-novel-mouse-cre-driver-line-targeting-perilipin-2-expressing-cells-in-the-neonatal-lung
#16
Aglaia Ntokou, Marten Szibor, José Alberto Rodríguez-Castillo, Jennifer Quantius, Susanne Herold, Elie El Agha, Saverio Bellusci, Isabelle Salwig, Thomas Braun, Robert Voswinckel, Werner Seeger, Rory E Morty, Katrin Ahlbrecht
Pulmonary diseases such as chronic obstructive pulmonary disease, lung fibrosis, and bronchopulmonary dysplasia are characterized by the destruction or malformation of the alveolar regions of the lung. The underlying pathomechanisms at play are an area of intense interest since these mechanisms may reveal pathways suitable for interventions to drive reparative processes. Lipid-laden fibroblasts (lipofibroblasts) express the Perilipin 2 (Plin2) gene-product, PLIN2, commonly called adipose-differentiation related protein (ADRP)...
October 16, 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28983908/interventions-for-managing-medication-related-osteonecrosis-of-the-jaw
#17
REVIEW
Natalie H Beth-Tasdogan, Benjamin Mayer, Heba Hussein, Oliver Zolk
BACKGROUND: Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some individuals to certain medicines commonly used in the treatment of cancer and osteoporosis (e.g. bisphosphonates, denosumab and antiangiogenic agents) and involves the progressive destruction of bone in the mandible or maxilla. Depending on the drug, its dosage, and the duration of exposure, the occurrence of this adverse drug reaction may be rare (e.g. following the oral administration of bisphosphonate or denosumab treatments for osteoporosis, or antiangiogenic agent-targeted cancer treatment) or common (e...
October 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28969742/basal-cell-adenoma-of-hard-palate-involving-maxillary-alveolus
#18
Manas Bajpai, Nilesh Pardhe, Betina Chandolia, Manika Arora
Minor salivary glands are relatively rare location for these tumors. Microscopically, they are composed of isomorphic cells, similar to basaloid cells with palisading arrangement and distinctive basement membrane like material. Herein, we report a case of BCApresenting as a soft tissue growth of left hard palate involving maxillary alveolus of a 41-year male.
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28969105/thyrolingual-trunk-arising-from-common-carotid-artery-a-case-report
#19
Santhosh Kumar Nochikattil, T P Sajith Babu, Sudheesh Manoharan
Superior Thyroid Artery (STA) usually arises from the ventral surface of the External Carotid Artery (ECA) just below the level of tip of greater cornu of hyoid bone and it runs anteriorly, downwards and medially. Lingual artery arises at the level of tip of greater cornu of hyoid bone and it runs anteriorly, upwards and medially. Rarely, both STA and lingual artery may originate as a common trunk called thyrolingual trunk. But a thyrolingual trunk arising from Common Carotid Artery (CCA) is very rare. We report a case of patient diagnosed to have carcinoma of right lower alveolus with nodal recurrence; with thyrolingual trunk arising from the medial aspect of CCA, which was detected incidentally during neck dissection...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28953728/three-dimensional-cone-beam-computed-tomography-volumetric-outcomes-of-rhbmp-2-demineralized-bone-matrix-versus-iliac-crest-bone-graft-for-alveolar-cleft-reconstruction
#20
Fan Liang, Stephen L-K Yen, Thomas Imahiyerobo, Luke Sanborn, Leia Yen, Daniel Yen, Sheila Nazarian, Breanna Jedrzejewski, Mark Urata, Jeffrey Hammoudeh
BACKGROUND: Recent studies indicate that recombinant human bone morphogenetic protein-2 (rhBMP-2) in a demineralized bone matrix scaffold is a comparable alternative to iliac bone autograft in the setting of secondary alveolar cleft repair. Postreconstruction occlusal radiographs demonstrate improved bone stock when rhBMP-2/demineralized bone matrix (DBM) scaffold is used but lack the capacity to evaluate bone growth in three dimensions. This study uses cone beam computed tomography to provide the first clinical evaluation of volumetric and density comparisons between these two treatment modalities...
October 2017: Plastic and Reconstructive Surgery
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