keyword
MENU ▼
Read by QxMD icon Read
search

Dia1 OR Dia-1

keyword
https://www.readbyqxmd.com/read/28642654/quantitative-evaluation-of-experimental-bone-regeneration-using-indentation-tests
#1
Valéria Trombini Vidotto, Nilza Alzira Batista, José Ricardo Lenzi Mariolani, William Dias Belangero
OBJECTIVES: To determine whether the macroindentation test can be applied to quantitatively assess bone regeneration. METHODS: A 3.2 mm diameter transverse monocortical defect was created on the medial aspect of both proximal metaphyses of the tibia of male Unib-WH rats. For the macroindentation tests, we used 5.00 mm diameter indenters with a 3.2 mm tip. Defect testing was performed 1 to 12 weeks following the surgical procedures to compare the hardness of the newly developed tissue over the 12-week study period...
March 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28642580/a-snake-venom-group-iia-pla2-with-immunomodulatory-activity-induces-formation-of-lipid-droplets-containing-15-d-pgj2-in-macrophages
#2
Karina Cristina Giannotti, Elbio Leiguez, Ana Eduarda Zulim de Carvalho, Neide Galvão Nascimento, Márcio Hideki Matsubara, Consuelo Latorre Fortes-Dias, Vanessa Moreira, Catarina Teixeira
Crotoxin B (CB) is a catalytically active group IIA sPLA2 from Crotalus durissus terrificus snake venom. In contrast to most GIIA sPLA2s, CB exhibits anti-inflammatory effects, including the ability to inhibit leukocyte functions. Lipid droplets (LDs) are lipid-rich organelles associated with inflammation and recognized as a site for the synthesis of inflammatory lipid mediators. Here, the ability of CB to induce formation of LDs and the mechanisms involved in this effect were investigated in isolated macrophages...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28641139/hormonal-profile-and-the-role-of-cell-expansion-in-the-germination-control-of-cerrado-biome-palm-seeds
#3
Daiane Souza Dias, Leonardo Monteiro Ribeiro, Paulo Sérgio Nascimento Lopes, Sergi Munné-Bosch, Queila Souza Garcia
Little information is currently available concerning the mechanisms controlling palm seed germination. We compared the anatomical and physiological aspects of seeds of two neotropical palm species showing different levels of dormancy. The seeds of Attalea vitrivir and Butia capitata were evaluated for the endogenous contents of hormones (ABA, GAs, CKs, BRs, IAA, JA, SA and the ethylene precursor ACC) in their cotyledonary petiole and operculum (structures involved in germination control), the force necessary to displace the operculum, endo-β-mannanase activities, and embryo cell elongation...
June 15, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28639108/fructose-1-6-bisphosphate-reverts-iron-induced-phenotype-of-hepatic-stellate-cells-by-chelating-ferrous-ions
#4
Henrique Bregolin Dias, Gabriele Catyana Krause, Eamin Daidrê Squizani, Kelly Goulart Lima, Aline Daniele Schuster, Leonardo Pedrazza, Bruno de Souza Basso, Bianca Andrade Martha, Fernanda Cristina de Mesquita, Fernanda Bordignon Nunes, Márcio Vinicius Fagundes Donadio, Jarbas Rodrigues de Oliveira
Hepatic fibrosis is an extracellular matrix deposition by hepatic stellate cells (HSC). Fibrosis can be caused by iron, which will lead to hydroxyl radical production and cell damage. Fructose-1,6-bisphosphate (FBP) has been shown to deliver therapeutic effects in many pathological situations. In this work, we aimed to test the effects of FBP in HSC cell line, GRX, exposed to an excess of iron (Fe). The Fe-treatment increased cell proliferation and FBP reversed this effect, which was not due to increased necrosis, apoptosis or changes in cell cycle...
June 21, 2017: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
https://www.readbyqxmd.com/read/28634333/atomic-rearrangement-of-a-sputtered-mos2-film-from-amorphous-to-a-2d-layered-structure-by-electron-beam-irradiation
#5
Bong Ho Kim, Hyun Ho Gu, Young Joon Yoon
We synthesised a crystalline MoS2 film from as-sputtered amorphous film by applying an electron beam irradiation (EBI) process. A collimated electron beam (60 mm dia.) with an energy of 1 kV was irradiated for only 1 min to achieve crystallisation without an additional heating process. After the EBI process, we observed a two-dimensional layered structure of MoS2 about 4 nm thick and with a hexagonal atomic arrangement on the surface. A stoichiometric MoS2 film was confirmed to grow well on SiO2/Si substrates and include partial oxidation of Mo...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28632041/automated-volumetry-of-hippocampus-is-useful-to-confirm-unilateral-mesial-temporal-sclerosis-in-patients-with-radiologically-positive-findings
#6
Guilherme Silva, Cristina Martins, Nádia Moreira da Silva, Duarte Vieira, Dias Costa, Ricardo Rego, José Fonseca, João Paulo Silva Cunha
Background and purpose We evaluated two methods to identify mesial temporal sclerosis (MTS): visual inspection by experienced epilepsy neuroradiologists based on structural magnetic resonance imaging sequences and automated hippocampal volumetry provided by a processing pipeline based on the FMRIB Software Library. Methods This retrospective study included patients from the epilepsy monitoring unit database of our institution. All patients underwent brain magnetic resonance imaging in 1.5T and 3T scanners with protocols that included thin coronal T2, T1 and fluid-attenuated inversion recovery and isometric T1 acquisitions...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28631826/effects-of-dietary-supplementation-of-red-pepper-schinus-terebinthifolius-raddi-essential-oil-on-performance-small-intestinal-morphology-and-microbial-counts-of-weanling-pigs
#7
Pedro Leon Gomes Cairo, Franz Dias Gois, Maicon Sbardella, Hebert Silveira, Roberto Maciel de Oliveira, Ivan Bezerra Allaman, Vinicius Souza Cantarelli, Leandro Batista Costa
BACKGROUND: Many strategies have been developed to improve intestinal health and performance of newly weaned piglets as the antibiotic growth promoters. Natural products such as essential oils have been scientifically recognized as growth enhancer feed additives for weanling pigs, replacing the antibiotics. Therefore, it has been hypothesized that Brazilian red pepper could replace performance-enhancing antibiotics also in weanling pig diets. However, one experiment was conducted to determine the effects of dietary Brazilian red pepper essential oil or antimicrobial growth promoter on intestinal health and growth performance of weanling pigs...
June 20, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28629912/calprotectin-and-the-magnitude-of-antibodies-to-infliximab-in-clinically-stable-ulcerative-colitis-patients-are-more-relevant-than-infliximab-trough-levels-and-pharmacokinetics-for-therapeutic-escalation
#8
Fernando Magro, Joana Afonso, Susana Lopes, Rosa Coelho, Raquel Gonçalves, Paulo Caldeira, Paula Lago, Helena Tavares de Sousa, Jaime Ramos, Ana Rita Gonçalves, Paula Ministro, Isadora Rosa, Ana Isabel Vieira, Patrícia Andrade, João-Bruno Soares, Diana Carvalho, Paula Sousa, Tânia Meira, Joanne Lopes, Joana Moleiro, Cláudia Camila Dias, Amílcar Falcão, Karel Geboes, Fatima Carneiro
Although infliximab (IFX) is an efficient therapy for ulcerative colitis (UC) patients, a considerably high rate of therapeutic failures still occurs. This study aimed at a better understanding of IFX pharmacokinetics and pharmacodynamics among clinically-asymptomatic UC patients. This was a multicentric and prospective study involving 65 UC patients in the maintenance phase of IFX therapy. There were no significant differences between patients with positive and negative clinical, endoscopic and histological outcomes concerning their IFX trough levels (TLs), area under the IFX concentration vs...
June 7, 2017: EBioMedicine
https://www.readbyqxmd.com/read/28628383/cardiovascular-response-of-an-acute-exergame-session-in-prepubertal-obese-children
#9
Herikson Araújo Costa, Antonio Carlos Silva-Filho, Carlos José Dias, Vicenilma Andrade Martins, Thiago Mendes, André Rabelo, Francisco Navarro, Emerson Silami-Garcia, Cristiano Mostarda, Mario Sevílio
PURPOSE: We aimed to analyze the acute autonomic response of obese and eutrophic prepubertal boys to an exergame (EXG) session. MATERIALS AND METHOD: Nine eutrophic (8.89 ± 2.71 years of age and 16.42% ± 6.30% body fat) and nine obese boys (8.70 ± 1.16 years of age and 40.76% ± 4.2% body fat) participated. Nutritional state was determined using World Health Organization guidelines. Variables were collected at rest, immediately post (IP), and 60 minutes after a 20 minutes EXG session...
June 2017: Games for Health
https://www.readbyqxmd.com/read/28627185/adherencia-y-tolerancia-como-claves-en-la-detenci%C3%A3-n-de-la-p%C3%A3-rdida-de-peso-en-pacientes-oncol%C3%A3-gicos-sometidos-a-radioterapia-mediante-una-estrategia-de-suplementaci%C3%A3-n-precoz-con-una-f%C3%A3-rmula-enteral-hipercal%C3%A3-rica-e-hiperproteica-espec%C3%A3-fica
#10
Jose M García Almeida, Yolanda Lupiáñez Pérez, Mercedes Blanco Naveira, Josefina Ruiz Nava, José Antonio Medina, Isabel Cornejo Pareja, Ana Gómez Pérez, María Molina Vega, José A López-Medina, Francisco Tinahones Madueño
Introducción: en pacientes con riesgo nutricional, la Sociedad Europea de Clínica y Metabolismo (ESPEN) y Parenteral recomienda suplementos nutricionales durante el tratamiento oncológico para prevenir la pérdida de peso involuntaria.Objetivos: nuestro objetivo es conocer el cumplimiento, la aceptabilidad y la tolerancia de un suplemento hiperproteico, hipercalórico, rico en omega 3 en pacientes oncológicos.Métodos: estudio unicéntrico, observacional y prospectivo en pacientes oncológicos con un suplemento nutricional hiperproteico, hipercalórico, rico en omega 3 y de bajo volumen...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28627182/factores-predictores-de-hipertrigliceridemia-en-pacientes-hospitalizados-con-nutrici%C3%A3-n-parenteral-total
#11
Maria Julia Ocón Bretón, Ana Isabel Ilundain Gonzalez, Jara Altemir Trallero, Ana Agudo Tabuenca, José Antonio Gimeno Orna
Introducción:la nutrición parenteral total (NPT) es una modalidad de soporte nutricional indicada en aquellas situaciones donde el enfermo no puede cubrir sus requerimientos nutricionales por vía enteral. A pesar de ser una terapia segura y efi caz, no está exenta de complicaciones, entre las que cabe destacar, por su frecuencia, la hipertrigliceridemia. La etiología de esta complicación metabólica es compleja y multifactorial.Objetivos: el objetivo de este trabajo fue determinar los factores de riesgo asociados al desarrollo de hipertrigliceridemia en pacientes adultos hospitalizados no críticos que reciben NPT a corto plazo y evaluar el efecto que una emulsión lipídica enriquecida en ácidos grasos poliinsaturados omega-3 ejerce sobre esta complicación metabólica...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28626980/comparison-of-management-regimens-following-ultrasound-diagnosis-of-nontubal-ectopic-pregnancies-a-retrospective-cohort-study
#12
J Ramkrishna, G R Kan, K L Reidy, W C Ang, R Palma-Dias
OBJECTIVE: To review management options for nontubal ectopic pregnancies. DESIGN: Retrospective cohort study. SETTING: Tertiary hospital in Melbourne, Australia. POPULATION: A total of 100 nontubal pregnancies: 1 abdominal, 32 caesarean scar, 14 cervical, 41 cornual-interstitial, 12 ovarian. METHODS: Cases were classified according to ectopic site. Management categories were medical, surgical, combination or expectant...
June 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28625437/inhalation-versus-intravenous-anaesthesia-for-adults-undergoing-on-pump-or-off-pump-coronary-artery-bypass-grafting-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#13
REVIEW
Regina El Dib, José E Guimarães Pereira, Arnav Agarwal, Huda Gomaa, Ana Patricia Ayala, Andresa Graciutti Botan, Leandro Gobbo Braz, Luciane Dias de Oliveira, Luciane Cruz Lopes, Preethy J Mathew
STUDY OBJECTIVE: To compare the use of inhalation versus intravenous anaesthesia for adults undergoing on-pump or off-pump coronary artery bypass grafting. DESIGN: A systematic review. SETTING: A hospital-affiliated university. MEASUREMENTS: The following databases were searched: the Cochrane Central Register of Controlled Trials (CENTRAL 2016, Issue 10), MEDLINE, EMBASE, and LILACS (from inception to October 2016). We used the GRADE approach to rate overall certainty of the evidence...
August 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28623690/candidate-cytochrome-p450-genes-for-ethoxyresorufin-o-deethylase-activity-in-oyster-crassostrea-gigas
#14
Marília Nardelli Siebert, Jacó Joaquim Mattos, Guilherme Toledo-Silva, Guilherme Razzera, Afonso Celso Dias Bainy
Vertebrate cytochrome P450 1 (CYP1) enzymes metabolize endogenous and xenobiotic compounds and usually demonstrate a substrate-inducible response. Ethoxyresorufin O-deethylase activity (EROD) is a common method to quantify CYP1 enzymes activity in these organisms. Despite the absence of this gene family in protostomes, CYP1-like genes were identified in several species, even though no evolutionary relationship has been established with the vertebrate CYP1 family. In the present study, EROD activity was evaluated in microsomal fraction of gills, digestive gland and mantle of Crassostrea gigas...
June 9, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28619148/antigenic-diversity-of-brazilian-isolates-of-hobi-like-pestiviruses
#15
R K Dias, J F Cargnelutti, M N Weber, C W Canal, F V Bauermann, J F Ridpath, R Weiblen, E F Flores
Hobi-like viruses comprise an unclassified group of bovine pestiviruses related to bovine viral diarrhea virus 1 (BVDV-1) and 2 (BVDV-2). These viruses were originally identified in fetal bovine serum from Brazilian origin and, subsequently, isolated from diseased animals in several countries. Herein we performed an antigenic characterization of eight Brazilian HoBi-like viruses isolated from persistently infected (PI) animals and from gastroenteric disease (2007-2015). Phylogenetic analysis based on the 5' unstranslated region (UTR) clustered these viruses with other HoBi-like viruses from European and Asiatic origin...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28618664/an-epidemiological-approach-to-characterise-the-human-exposure-pathways-in-a-contaminated-estuarine-environment
#16
Ausenda Machado, Ana Paula Fernandes, Eleonora Paixão, Sandra Caeiro, Carlos Matias-Dias
This study's aim was to develop and implement an integrative epidemiologic cross-sectional study that allows identifying and characterising exposure pathways of populations living and working on the shores of a contaminated estuarine environment. Population residing in Carrasqueira, located on the Sado estuary with known contaminated areas was compared to another population on a noncontaminated estuary (Vila Nova de Mil Fontes - VNMF), considered a nonexposed population. Simple random samples of individuals were selected in each study population from the National Health Service Lists: 140 individuals were selected in Carrasqueira and 219 in VNMF...
June 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28618060/clinical-validation-of-the-nursing-diagnosis-of-ineffective-protection-in-hemodialysis-patients
#17
Jéssica Dantas de Sá Tinôco, Maria das Graças Mariano Nunes de Paiva, Cecília Maria Farias de Queiroz Frazão, Kadyjina Daiane Batista Lucio, Maria Isabel da Conceição Dias Fernandes, Marcos Venicios de Oliveira Lopes, Ana Luisa Brandão de Carvalho Lira
AIMS AND OBJECTIVES: The aim of this study was to evaluate the clinical validity of indicators of the nursing diagnosis of "ineffective protection" in hemodialysis patients. BACKGROUND: Hemodialysis patients have reduced protection. Studies on the nursing diagnosis of "ineffective protection" are scarce in the literature. The use of indicators to diagnose "ineffective protection" could improve the care of hemodialysis patients. The clinical usefulness of the indicators requires clinical validation...
June 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28613385/expanded-conventional-first-trimester-screening
#18
Jonathan B Carmichael, Hsiao-Pin Liu, David Janik, Terrence W Hallahan, Kypros H Nicolaides, David A Krantz
OBJECTIVE: To determine the performance of a five (5) serum marker plus ultrasound screening protocol for T21, T18 and T13. METHOD: Specimens from 331 unaffected, 34 T21, 19 T18 and 8 T13 cases were analyzed for free Beta hCG, PAPP-A, AFP, PlGF and dimeric inhibin A (DIA). Gaussian distributions of MoM values were used to estimate modeled false positive and detection rates. RESULTS: For T21, at a 1/300 risk cut-off, detection rate of screening with all five serum markers along with nuchal translucency and nasal bone was 98% at a 1...
June 14, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28611606/long-term-sertraline-intake-reverses-the-behavioral-changes-induced-by-prenatal-stress-in-rats-in-a-sex-dependent-way
#19
Inês Pereira-Figueiredo, Orlando Castellano, Adelaida S Riolobos, Graça Ferreira-Dias, Dolores E López, Consuelo Sancho
Early life stress is a major factor underlying the vulnerability to respond to stressful events later in life. The present study attempted to evaluate the role of prenatal stress affecting the development of stress-related disorders and their reversion by postnatal exposure to Sertraline (SERT), a front-line medication for medication for posttraumatic stress disorder (PTSD) in humans. To achieve this, adult male and female prenatally stressed (PS) or unstressed (Controls) offspring rats, following oral chronic treatment with SERT (5 mg/kg/day; from 1 month to 4 months old), or not, were studied prior to and after a traumatic event...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28610992/anti-liver-cancer-activity-in-vitro-and-in-vivo-induced-by-2-pyridyl-2-3-thiazole-derivatives
#20
Thiago David Dos Santos Silva, Larissa Mendes Bomfim, Ana Carolina Borges da Cruz Rodrigues, Rosane Borges Dias, Caroline Brandi Schlaepfer Sales, Clarissa Araújo Gurgel Rocha, Milena Botelho Pereira Soares, Daniel Pereira Bezerra, Marcos Veríssimo de Oliveira Cardoso, Ana Cristina Lima Leite, Gardenia Carmen Gadelha Militão
A total of 24 hybrid compounds containing pyridyl and 1,3-thiazole moieties were screened against HL-60 (leukemia), MCF-7 (breast adenocarcinoma), HepG2 (hepatocellular carcinoma), NCI-H292 (lung carcinoma) human tumor cell lines and non-tumor cells (PBMC, human peripheral blood mononuclear cells). Most of them were highly potent in at least one cell line tested (IC50≤3μM), being HL-60 the most sensitive and HepG2 the most resistant cell line. Among them, TAP-07 and TP-07 presented cytotoxic activity in all tumor cell lines, including HepG2 (IC50 2...
June 10, 2017: Toxicology and Applied Pharmacology
keyword
keyword
88893
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"