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Association schizophrenia logistic regression

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https://www.readbyqxmd.com/read/28433088/parental-age-and-offspring-psychopathology-in-the-philadelphia-neurodevelopmental-cohort
#1
Alison K Merikangas, Monica E Calkins, Warren B Bilker, Tyler M Moore, Ruben C Gur, Raquel E Gur
OBJECTIVE: Increasing evidence implicates advanced paternal age at offspring birth in neuropsychiatric disorders. Advanced maternal age has also been associated with schizophrenia and other neurodevelopmental disorders, whereas younger maternal age has been linked with behavioral disorders. Few studies have considered the specificity of the associations with respect to comorbidity. In addition, most prior studies have been conducted in clinical samples or registries that may reflect more severe forms of psychopathology...
May 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28429844/a-comparison-of-clinical-characteristics-of-older-adults-treated-with-antidepressants-in-general-and-psychiatric-hospitals-in-asia
#2
Yuan-Yuan Wang, Yu-Tao Xiang, Gabor S Ungvari, Chee H Ng, Helen F K Chiu, Larina C L Yim, Tian-Mei Si, Kok-Yoon Chee, Ajit Avasthi, Sandeep Grover, Mian-Yoon Chong, Kang Sim, Shigenobu Kanba, Yan-Ling He, Min-Soo Lee, Shu-Yu Yang, Pichet Udomratn, Roy A Kallivayalil, Andi J Tanra, Margarita M Maramis, Winston W Shen, Norman Sartorius, Rathi Mahendran, Jia-Ying Teng, Chay-Hoon Tan, Naotaka Shinfuku
AIM: This study compared the demographics, clinical characteristics, and antidepressant prescription patterns between Asian patients aged 50 years and older attending psychiatric hospitals and those attending general hospitals. METHODS: In total, 955 patients (604 in general hospitals, 351 in psychiatric hospitals) aged 50 years or older treated with antidepressants in 10 Asian countries and territories were examined. Patients' demographics, clinical features, and prescriptions of psychotropic drugs were recorded using a standardized protocol and data collection procedure...
April 21, 2017: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/28411576/a-population-based-study-of-premorbid-scholastic-achievement-among-patients-with-psychiatric-disorders
#3
Vardit Zerem Ullman, Tzipi Hornik-Lurie, Abraham Reichenberg
Population-based studies of premorbid cognitive functioning in schizophrenia have found verbal deficits and low IQ scores. It remains unclear, however, whether premorbid deficits are specific to schizophrenia, compared with other psychiatric disorders. Moreover, studies using school-based measures are few and their results inconsistent. This study assesses the eighth-grade (ages 13-14; n=11, 418) scholastic performance of adults with psychiatric disorders (n=194, 1.7, particularly with schizophrenia (n=86, 0...
April 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28407747/antipsychotic-prescribing-for-vulnerable-populations-a-clinical-audit-at-an-acute-australian-mental-health-unit-at-two-time-points
#4
Sara S McMillan, Sara Jacobs, Louise Wilson, Theo Theodoros, Gail Robinson, Claire Anderson, Gabor Mihala, Amanda J Wheeler
BACKGROUND: Antipsychotics are recognised as a critical intervention for schizophrenia and bipolar disorder. Guidelines globally endorse the routine practice of antipsychotic monotherapy, at the minimum effective dose. Even in treatment-resistant schizophrenia, clozapine use is endorsed before combining antipsychotics. This aim of this study was to review antipsychotic polytherapy alone, high-dose therapy alone, polytherapy and high-dose prescribing patterns in adults discharged from an inpatient mental health unit at two time-points, and the alignment of this prescribing with clinical guideline recommendations...
April 13, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28400569/association-between-schizophrenia-and-violence-among-chinese-female-offenders
#5
Jun Wang, Chun Li, Xiao-Min Zhu, Si-Mei Zhang, Jian-Song Zhou, Qi-Guang Li, Qun Wang, Shao-Ling Zhong, Chee H Ng, Gabor S Ungvari, Yu-Tao Xiang, Xiao-Ping Wang
Little is known about the association between schizophrenia and violence in women in China. This study aimed to examine the association between schizophrenia and violence in Chinese female offenders. Fifty-two schizophrenia patients were identified from the female offenders who received forensic psychiatric assessments in 2011 in Hunan province, China. Using a propensity score matching method, 104 matched controls without psychiatric disorders were selected from female criminals in Hunan province. Violent offences and homicides were verified and recorded...
April 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28399842/deficits-of-perceived-spatial-separation-induced-prepulse-inhibition-in-patients-with-schizophrenia-relationships-to-symptoms-and-neurocognition
#6
Ning-Bo Yang, Qing Tian, Yu Fan, Qi-Jing Bo, Liang Zhang, Liang Li, Chuan-Yue Wang
BACKGROUND: Prepulse inhibition (PPI) and attention were impaired, which may cause psychotic symptoms and (or) hinder the cognitive functions in schizophrenia. However, due to the measurement methods of PPI, findings about the relationship between PPI and clinical symptoms, cognitive performances have been equivocal. METHODS: Seventy-five schizophrenia patients (SZ) and 50 healthy controls (HC) were assessed in a modified acoustic PPI paradigm, named perceived spatial separation-induced PPI (PSS-PPI), compared to perceived spatial co-location PPI (PSC-PPI) with inter-stimulus interval (ISI) of 120 ms...
April 11, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28391108/mitochondrial-genetic-haplogroups-and-depressive-symptoms-a-large-study-among-people-in-north-america
#7
Nicola Veronese, Brendon Stubbs, Marco Solmi, Alberto Vaona, Jacopo Demurtas, Andre F Carvalho, Ai Koyanagi, Trevor Thompson, Mario Zoratti, Stefania Maggi
BACKGROUND: A possible relationship between mitochondrial haplogroups and psychiatric diseases (e.g. schizophrenia and bipolar disorder) has been postulated, but data regarding depression is still limited. We investigated whether any mitochondrial haplogroup carried a significant higher risk of depressive symptoms in a large prospective cohort of North American people included in the Osteoarthritis Initiative. METHODS: Cross sectional data was derived from the Osteoarthritis Initiative...
April 4, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28385492/reduced-white-matter-integrity-and-facial-emotion-perception-in-never-medicated-patients-with-first-episode-schizophrenia-a-diffusion-tensor-imaging-study
#8
Xiaoxin Zhao, Yuxiu Sui, Jingjing Yao, Yiding Lv, Xinyue Zhang, Zhuma Jin, Lijun Chen, Xiangrong Zhang
BACKGROUND: Facial emotion perception is impaired in schizophrenia. Although the pathology of schizophrenia is thought to involve abnormality in white matter (WM), few studies have examined the correlation between facial emotion perception and WM abnormalities in never-medicated patients with first-episode schizophrenia. The present study tested associations between facial emotion perception and WM integrity in order to investigate the neural basis of impaired facial emotion perception in schizophrenia...
April 4, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28368180/predictors-of-response-to-cognitive-remediation-in-service-recipients-with-severe-mental-illness
#9
Jean-Pierre Lindenmayer, Veronica Anna Ozog, Anzalee Khan, Isidora Ljuri, Samantha Fregenti, Susan R McGurk
OBJECTIVE: Cognitive challenges are prominent features of individuals diagnosed with schizophrenia, impairing occupational, social, and economic functioning. These challenges are predictive of social and work outcomes. Cognitive remediation has been shown to be effective in improving both cognitive and social functions. However, cognitive remediation does not produce improvement in all participants. We investigated demographic, neurocognitive, and psychopathological predictors associated with improvement following cognitive remediation interventions in service recipients with severe mental illnesses...
March 2017: Psychiatric Rehabilitation Journal
https://www.readbyqxmd.com/read/28367774/the-singaporean-public-beliefs-about-the-causes-of-mental-illness-results-from-a-multi-ethnic-population-based-study
#10
S Pang, M Subramaniam, S P Lee, Y W Lau, E Abdin, B Y Chua, L Picco, J A Vaingankar, S A Chong
AIMS: To identify the common causal beliefs of mental illness in a multi-ethnic Southeast Asian community and describe the sociodemographic associations to said beliefs. The factor structure to the causal beliefs scale is explored. The causal beliefs relating to five different mental illnesses (alcohol abuse, depression, obsessive-compulsive disorder (OCD), dementia and schizophrenia) and desire for social distance are also investigated. METHODS: Data from 3006 participants from a nationwide vignette-based study on mental health literacy were analysed using factor analysis and multiple logistic regression to address the aims...
April 3, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28349344/long-term-abstinence-and-predictors-of-tobacco-treatment-uptake-among-hospitalized-smokers-with-serious-mental-illness-enrolled-in-a-smoking-cessation-trial
#11
Erin S Rogers, Rebecca Friedes, Annika Jakes, Ellie Grossman, Alissa Link, Scott E Sherman
Hospital patients with serious mental illness (SMI) have high rates of smoking. There are few post-discharge treatment models available for this population and limited research on their treatment uptake following discharge. This study is a secondary analysis of an RCT that compared multi-session intensive telephone counseling versus referral to state quitline counseling at two safety net hospitals in New York City. For this analysis, we selected all trial participants with a history of schizophrenia, schizoaffective disorder or bipolar disorder (N = 384) and used multivariable logistic regression to compare groups on self-reported 30-day abstinence at 6 months and to identify patient factors associated with use of tobacco treatment...
March 27, 2017: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/28346041/enhancing-tolerability-of-a-measure-of-social-perception-in-schizophrenia-comparison-of-short-and-long-norwegian-versions-of-the-relationships-across-domains-test
#12
Anja Vaskinn, Alan P Fiske, Michael F Green
INTRODUCTION: Relationship perception focuses on social interactions, is reduced in schizophrenia and is related to daily functioning. It can be assessed with the Relationships Across Domains (RAD) test, built on Relational Models Theory which states that people use four relational models to interpret social interaction. RAD is time consuming, low on tolerability and only used in English-speaking countries. We evaluated the psychometric properties of a translated, abbreviated Norwegian version...
March 27, 2017: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/28280344/metabolic-profile-at-first-time-schizophrenia-diagnosis-a-population-based-cross-sectional-study
#13
Henriette Thisted Horsdal, Michael Eriksen Benros, Ole Köhler-Forsberg, Jesper Krogh, Christiane Gasse
OBJECTIVE: Schizophrenia and/or antipsychotic drug use are associated with metabolic abnormalities; however, knowledge regarding metabolic status and physician's monitoring of metabolic status at first schizophrenia diagnosis is sparse. We assessed the prevalence of monitoring for metabolic blood abnormalities and characterized the metabolic profiles in people with a first-time schizophrenia diagnosis. METHODS: This is a population-based cross-sectional study including all adults born in Denmark after January 1, 1955, with their first schizophrenia diagnosis between 2000 and 2012 in the Central Denmark Region...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28273629/insight-and-suicidality-in-psychosis-a-cross-sectional-study
#14
Carmen Massons, Javier-David Lopez-Morinigo, Esther Pousa, Ada Ruiz, Susana Ochoa, Judith Usall, Lourdes Nieto, Jesus Cobo, Anthony S David, Rina Dutta
AIMS: We aimed to test whether specific insight dimensions are associated with suicidality in patients with psychotic disorders. METHODS: 143 patients with schizophrenia spectrum disorders were recruited. Suicidality was assessed by item 8 of the Calgary Depression Scale for Schizophrenia (CDSS). Insight was measured by the Scale of Unawareness of Mental Disorder (SUMD) and the Markova and Berrios Insight Scale. Bivariate analyses and multivariable logistic regression models were conducted...
February 27, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28260128/expressed-emotion-and-the-course-of-schizophrenia-in-pakistan
#15
Sarosh Sadiq, Kausar Suhail, John Gleeson, Mario Alvarez-Jimenez
PURPOSE: Aim of the study is to evaluate the predictive power of Expressed Emotion in Schizophrenia relapse in Pakistan. METHOD: A longitudinal study was conducted comprising 53 in-patients' sample diagnosed with Schizophrenia and their 101 key carers. Participants fulfilled DSM-IV-TR criteria for Schizophrenia based on Structural Clinical Interview for the DSM-IV diagnosis. Symptomatic status was measured through Brief Psychiatric Rating Scales-Expanded (BPRS-E)...
March 4, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28252572/pharmacogenetics-of-ketamine-induced-emergence-phenomena-a-pilot-study
#16
Edwin N Aroke, Sybil L Crawford, Jennifer R Dungan
BACKGROUND: Up to 55% of patients who are administered ketamine experience an emergence phenomena (EP) that closely mimics schizophrenia and increases their risk of injury; however, to date, no studies have investigated genetic association of ketamine-induced EP in healthy patients. OBJECTIVES: The aim of the study was to investigate the feasibility and sample sizes required to explore the relationship between CYP2B6*6 and GRIN2B single-nucleotide polymorphisms and ketamine-induced EP...
March 2017: Nursing Research
https://www.readbyqxmd.com/read/28222824/curiosity-killed-the-cat-no-evidence-of-an-association-between-cat-ownership-and-psychotic-symptoms-at-ages-13-and-18-years-in-a-uk-general-population-cohort
#17
F Solmi, J F Hayes, G Lewis, J B Kirkbride
BACKGROUND: Congenital or early life infection with Toxoplasma gondii has been implicated in schizophrenia aetiology. Childhood cat ownership has been hypothesized as an intermediary marker of T. gondii infection and, by proxy, as a risk factor for later psychosis. Evidence supporting this hypothesis is, however, limited. METHOD: We used birth cohort data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to investigate whether cat ownership in pregnancy and childhood (ages 4 and 10 years) was associated with psychotic experiences (PEs) in early (age 13, N = 6705) and late (age 18, N = 4676) adolescence, rated from semi-structured interviews...
February 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28183293/using-video-annotation-software-to-identify-interactions-in-group-therapies-for-schizophrenia-assessing-reliability-and-associations-with-outcomes
#18
Stavros Orfanos, Syeda Ferhana Akther, Muhammad Abdul-Basit, Rosemarie McCabe, Stefan Priebe
BACKGROUND: Research has shown that interactions in group therapies for people with schizophrenia are associated with a reduction in negative symptoms. However, it is unclear which specific interactions in groups are linked with these improvements. The aims of this exploratory study were to i) develop and test the reliability of using video-annotation software to measure interactions in group therapies in schizophrenia and ii) explore the relationship between interactions in group therapies for schizophrenia with clinically relevant changes in negative symptoms...
February 10, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28177063/prevalence-of-and-factors-associated-with-antipsychotic-polypharmacy-in-patients-with-serious-mental-illness-findings-from-a-cross-sectional-study-in-an-upper-middle-income-country
#19
Kerryn S Armstrong, Henk Temmingh
Objective: The aim of our study was to examine the prevalence of and factors associated with antipsychotic polypharmacy (APP) among patients with serious mental illness in the current South African health care context. Methods: We collected data on patient, illness, and treatment characteristics of patients discharged on one or more antipsychotic agents from January to June 2014. We analyzed the associations of APP with demographic and clinical variables using hierarchical multivariable logistic regression, and examined prescription patterns...
February 6, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28160655/factors-associated-with-complete-discontinuation-of-medication-among-patients-with-schizophrenia-in-the-year-after-hospital-discharge
#20
Yanling Zhou, Robert Rosenheck, Somaia Mohamed, Yuping Ning, Hongbo He
Medication discontinuation is a major risk factor for relapse in schizophrenic patients. The present study investigated the rate and clinical correlates of complete medication discontinuation in the year after hospital discharge. Data collected from 236 schizophrenia patients who were prescribed anti-psychotics documented socio-demographic characteristics, symptom severity, insight, and attitudes towards medication in the week before their discharge and the experience of caregiver burden for their primary caregiver as recorded at the time of hospitalization...
January 17, 2017: Psychiatry Research
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