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JOURNAL ARTICLE
Yasuyuki Miyake, Yatsuki Aratake, Takuya Sakaguchi, Kazuaki Kiyoya, Tadanobu Kuribayashi, Kousuke Marutsuka, Eiji Ohno
Tumor cytology has proven to be inadequate for precise diagnosis of thyroid follicular adenoma. This suggests the need for a molecular approach for its diagnosis. Expression of CD26/DPPIV (dipeptidyl peptidas IV), p53, and PTEN was analyzed in smears or sections obtained from 19 patients with histologically proven thyroid follicular adenoma. Papanicolaou staining, CD26/DPPIV activity staining, and HE staining were performed and the specimens were observed morphologically. Immunohistochemical analysis using antibodies against p53 and PTEN was performed...
December 2012: Diagnostic Cytopathology
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