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https://www.readbyqxmd.com/read/28231627/factors-predicting-recovery-from-suicide-in-attempted-suicide-patients
#1
Fan-Ko Sun, Chu-Yun Lu, Yun Shan Tseng, Chun-Ying Chiang
AIMS AND OBJECTIVES: The aim of this study was to explore the factors predicting suicide recovery and to provide guidance for healthcare professionals when caring for individuals who have attempted suicide. BACKGROUND: The high rate of suicide is a global health problem. Suicide prevention has become an important issue in contemporary mental health. Most suicide research has focused on suicidal prevention and care. There is a lack of research on the factors predicting suicidal recovery DESIGN: A cross-sectional design was adopted...
February 23, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28231557/comparison-of-body-s-center-of-mass-motion-relative-to-center-of-pressure-between-treadmill-and-over-ground-walking
#2
Hsuan-Lun Lu, Tung-Wu Lu, Hsiu-Chen Lin, Wing P Chan
Treadmills have been used in rehabilitation settings to provide convenient protocols and continuous monitoring of movement over multiple cycles at well-controlled speeds for gait and balance training. However, the potential differences in the movement control may affect the translation of the training outcomes to real life over-ground walking (OW). The similarities and differences in the balance control between treadmill walking (TW) and OW have largely been unexplored. The current study bridged the gap by comparing the motions of the body's center of mass (COM) relative to the center of pressure (COP) between TW and OW, in terms of the COM-COP inclination angle (IA) and its rate of change (RCIA)...
February 9, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28231538/biochars-with-excellent-pb-ii-adsorption-property-produced-from-fresh-and-dehydrated-banana-peels-via-hydrothermal-carbonization
#3
Nan Zhou, Honggang Chen, Junting Xi, Denghui Yao, Zhi Zhou, Yun Tian, Xiangyang Lu
Fresh and dehydrated banana peels were used as biomass feedstock to produce highly effective sorbent biochars through a facile one-step hydrothermal carbonization approach with 20%vol phosphoric acid as the reaction medium. The elemental ratio of oxygen content of the two as-prepared biochars were about 20%, and the FT-IR analysis confirmed the existence of abundant surface functional groups such as hydroxyl and carboxyl which greatly enhanced the adsorption performance. The sorbents showed excellent lead clarification capability of 359mg·g(-1) and 193mg·g(-1) for dehydrated and fresh banana peels based biochars, respectively...
February 12, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28231517/measurements-of-x-ray-doses-and-spectra-produced-by-picosecond-laser-irradiated-solid-targets
#4
Bo Yang, Rui Qiu, Minghai Yu, Jinlong Jiao, Wei Lu, Yonghong Yan, Bo Zhang, Zhimeng Zhang, Weimin Zhou, Junli Li, Hui Zhang
Experiments have shown that high-intensity laser interaction with a solid target can generate significant X-ray doses. This study was conducted to determine the X-ray doses and spectra produced for picosecond laser-irradiated solid targets. The photon doses and X-ray spectra in the laser forward and side directions were measured using an XG III ps 300 TW laser system. For laser intensities of 7×10(18)-4×10(19)W/cm(2), the maximum photon dose was 16.8 mSv at 50cm with a laser energy of ~153J on a 1-mm Ta target...
February 9, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28231505/assessing-remobilization-characteristics-of-arsenic-as-in-tributary-sediment-cores-in-the-largest-reservoir-china
#5
Li Gao, Bo Gao, Dongyu Xu, Wenqi Peng, Jin Lu, Jijun Gao
The environmental impact of the Three Gorges Reservoir (TGR) in China has raised widespread concern especially in relation to metal pollution. The diffusive gradient in thin films (DGT) technology was applied to investigate arsenic (As) remobilization in sediment cores collected from the main stream and a tributary in the TGR during July 2015. The results showed that the horizontal and vertical distributions of CDGT-As varied among the four sampling sites. For the same DGT probe, the horizontal distributions of CDGT-As (0-6mm, 6-12mm, 12-18mm) exhibited similarity in the overlying water and different tendencies in the sediment profiles; the vertical variations of CDGT-As showed different mobilization tendencies...
February 20, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28231388/structural-characterization-and-antifatigue-effect-in-vivo-of-maca-lepidium-meyenii-walp-polysaccharide
#6
Weimin Tang, Lu Jin, Lianghua Xie, Juqing Huang, Nan Wang, Bingquan Chu, Xulin Dai, Yu Liu, Rui Wang, Ying Zhang
Maca (Lepidium meyenii Walp) polysaccharides (MP) with purity of 99.2% were obtained to investigate their structural characteristics and antifatigue effect in vivo. The physicochemical properties of MP were analyzed through high-performance gel filtration chromatography, IR, monosaccharide composition, methylation, GC-MS, and NMR analyses. The antifatigue effect of MP was evaluated by using a mouse weight-loaded swimming model. MP is an acidic heteropolysaccharide with an average molecular weight (Mw ) of 793...
February 23, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28231287/effect-of-high-dose-rosuvastatin-loading-before-percutaneous-coronary-intervention-in-chinese-patients-with-acute-coronary-syndrome-a-systematic-review-and-meta-analysis
#7
Ziliang Ye, Haili Lu, Qiang Su, Wenqin Guo, Weiran Dai, Hongqing Li, Huafeng Yang, Lang Li
BACKGROUND: Acute coronary syndrome (ACS) is an important disease threatening human life and health. Many studies have shown that the loading dose of atorvastatin can significantly improve the prognosis of patients with ACS, and reduce the mortality. However, this conclusion is not consistent. Thus, we aimed to evaluate the effect of high-dose rosuvastatin loading before percutaneous coronary intervention (PCI) in Chinese patients with ACS using a meta-analysis based on a systematic review of published articles...
2017: PloS One
https://www.readbyqxmd.com/read/28231233/association-of-topoisomerase-ii-top2a-and-dual-specificity-phosphatase-6-dusp6-single-nucleotide-polymorphisms-with-radiation-treatment-response-and-prognosis-of-lung-cancer-in-han-chinese
#8
Tian-Lu Wang, Yang-Wu Ren, He-Tong Wang, Hong Yu, Yu-Xia Zhao
BACKGROUND Mutations of DNA topoisomerase II (TOP2A) are associated with chemotherapy resistance, whereas dual-specificity phosphatase 6 (DUSP6) negatively regulates members of the mitogen-activated protein (MAP) kinase superfamily to control cell proliferation. This study assessed TOP2A and DUSP6 single nucleotide polymorphisms (SNPs) in non-small cell lung cancer (NSCLC) patients for association with chemoradiotherapy responses and prognosis. MATERIAL AND METHODS A total of 140 Chinese patients with histologically confirmed NSCLC were enrolled and subjected to genotyping of TOP2A rs471692 and DUSP6 rs2279574 using Taqman PCR...
February 23, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28231012/quantum-percolation-and-magnetic-nano-droplet-states-in-electronically-phase-separated-manganite-nanowires
#9
Kaixuan Zhang, Lin Li, Hui Li, Qiyuan Feng, Nan Zhang, Long Cheng, Xiaodong Fan, Yubin Hou, Qingyou Lu, Zhenyu Zhang, Changgan Zeng
One-dimensional (1D) confinement has been revealed to effectively tune the properties of materials in homogeneous states. The 1D physics can be further enriched by electronic inhomogeneity, which unfortunately remains largely unknown. Here we demonstrate the ultra-high sensitivity to magnetic fluctuations and the tunability of phase stability in the electronic transport properties of self-assembled electronically phase-separated manganite nanowires with extreme aspect ratio. The onset of magnetic nano-droplet state, a precursor to the ferromagnetic metallic state, is unambiguously revealed, which is attributed to the small lateral size of the nanowires that is comparable to the droplet size...
February 23, 2017: Nano Letters
https://www.readbyqxmd.com/read/28230988/design-and-synthesis-of-novel-cyclic-amine-benzimidazoles-for-the-treatment-of-pancreatic-cancer
#10
Vibha Pathak, Corinne Elizabeth Augelli-Szafran, Han-Xun Wei, Yonghe Li, Patsy G Oliver, Wenyan Lu, Donald J Buchsbaum, Mark J Suto
Wnt/beta-Catenin signaling pathway has a very important role in pancreatic ductal adenocarcinoma (PDAC) initiation and progression. This signaling pathway has been implicated in angiogenesis, maintenance of resistant CICs (cancer-initiating cells), metastasis, regulation of cell cycle, apoptosis and chemoresistance. We investigated the activity of a chemical series of phenyl benzimidazoles, small molecule inhibitors of Wnt signaling in LRP6-expressing HEK 293 cells against PDAC cells. Several benzimidazoles were designed, synthesized and screened under adherent and CIC conditions...
February 23, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28230978/a-label-free-method-using-a-weighted-phase-algorithm-to-quantitate-nanoscale-interactions-between-molecules-on-dna-microarrays
#11
Qi Li, Rongxin Fu, Junqi Zhang, Ruliang Wang, Jiancheng Ye, Ning Xue, Xue Lin, Ya Su, Wupeng Gan, Ying Lu, Guoliang Huang
White light interference is used as a label-free method to detect nanoscale changes on surfaces. However, the signal-to-noise ratio of the white light interference method is very low, thus resulting in inaccurate results. In this paper, we report a corrected label-free method based on hyperspectral interferometry to overcome the shortcoming of the white light interference method. A platform based on hyperspectral interferometry was established, and a DNA hybridization microarray was constructed to quantitate thickness variation of molecules on a solid surface...
February 23, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28230861/ripk3-interactions-with-mlkl-and-camkii-mediate-oligodendrocytes-death-in-the-developing-brain
#12
Yi Qu, Jun Tang, Huiqing Wang, Shiping Li, Fengyan Zhao, Li Zhang, Q Richard Lu, Dezhi Mu
Oligodendrocyte progenitor cells (OPCs) death is a key contributor to cerebral white matter injury (WMI) in the developing brain. A previous study by our group indicated that receptor-interacting proteins (RIPs) are crucial in mediating necroptosis in developing neurons. However, whether this mechanism is involved in OPCs death is unclear. We aimed to explore the mechanisms of RIP-mediated oligodendrocytes (OLs) death in the developing brain. Oligodendrocytes necroptosis was induced by oxygen-glucose deprivation plus caspase inhibitor zVAD treatment (OGD/zVAD) in vitro...
February 23, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28230854/opposite-effects-of-hdac5-and-p300-on-mrtf-a-related-neuronal-apoptosis-during-ischemia-reperfusion-injury-in-rats
#13
Na Li, Qiong Yuan, Xiao-Lu Cao, Ying Zhang, Zhen-Li Min, Shi-Qiang Xu, Zhi-Jun Yu, Jing Cheng, Chunxiang Zhang, Xia-Min Hu
Our recent study has revealed that the myocardin-related transcription factor-A (MRTF-A) is involved in the apoptosis of cortical neurons induced by ischemia/reperfusion (I/R). Histone deacetylase 5 (HDAC5) and histone acetyltransferase p300 (P300) are two well-known regulators for transcription factors; however, their roles in MRTF-A-related effect on neuronal injuries during I/R are still unclear. In this study, in a model rat cerebral I/R injury via middle cerebral artery occlusion and reperfusion, we found that the expression and activity of HDAC5 was upregulated, whereas p300 and MRTF-A were downregulated both in expression and activity during I/R...
February 23, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28230809/association-of-sleep-duration-sleep-quality-and-shift-work-schedule-in-relation-to-hypertension-prevalence-in-chinese-adult-males-a-cross-sectional-survey
#14
Kai Lu, Jia Chen, Li Wang, Changying Wang, Rongjing Ding, Shouling Wu, Dayi Hu
Background: Previous studies indicated that measurement of sleep only by duration and quality may be biased. This study aimed to investigate the interactive association of self-reported sleep duration, quality and shift-work schedule with hypertension prevalence in Chinese adult males. Methods: A total of 4519 Chinese adult males (≥18 years) were enrolled into the cross-sectional survey. Sleep attributes were measured from the responses to the standard Pittsburgh Sleep Quality Index and relevant questions in a structured questionnaire survey...
February 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28230775/prec-and-c-regions-of-woodchuck-hepatitis-virus-facilitate-persistent-expression-of-surface-antigen-of-chimeric-whv-hbv-virus-in-the-hydrodynamic-injection-balb-c-mouse-model
#15
Weimin Wu, Yan Liu, Yong Lin, Danzhen Pan, Dongliang Yang, Mengji Lu, Yang Xu
In the hydrodynamic injection (HI) BALB/c mouse model with the overlength viral genome, we have found that woodchuck hepatitis virus (WHV) could persist for a prolonged period of time (up to 45 weeks), while hepatitis B virus (HBV) was mostly cleared at week four. In this study, we constructed a series of chimeric genomes based on HBV and WHV, in which the individual sequences of a 1.3-fold overlength HBV genome in pBS-HBV1.3 were replaced by their counterparts from WHV. After HI with the WHV-HBV chimeric constructs in BALB/c mice, serum viral antigen, viral DNA (vDNA), and intrahepatic viral antigen expression were analyzed to evaluate the persistence of the chimeric genomes...
February 21, 2017: Viruses
https://www.readbyqxmd.com/read/28230774/inhibition-of-ccar1-a-coactivator-of-%C3%AE-catenin-suppresses-the-proliferation-and-migration-of-gastric-cancer-cells
#16
Te-Sheng Chang, Kuo-Liang Wei, Chung-Kuang Lu, Yi-Hsing Chen, Ying-Tung Cheng, Shui-Yi Tung, Cheng-Shyong Wu, Ming-Ko Chiang
The aberrant activation of Wnt signaling has been implicated in a variety of human cancers, including gastric cancer. Given the current hypothesis that cancer arises from cancer stem cells (CSCs), targeting the critical signaling pathways that support CSC self-renewal appears to be a useful approach for cancer therapy. Cell cycle and apoptosis regulator 1 (CCAR1) is a transcriptional coactivator which has been shown to be a component of Wnt/β-catenin signaling, and which plays an important role in transcriptional regulation by β-catenin...
February 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28230610/16s-rdna-gene-sequencing-analysis-in-functional-dyspepsia-treated-with-fecal-microbiota-transplantation
#17
Jiayi Wang, Jianlei Gu, Yizhong Wang, Kai Lin, Shiyi Liu, Hui Lu, Ting Zhang, Guangjun Yu
No abstract text is available yet for this article.
March 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28230537/core-shell-znco2o4-tio2-nanowall-array-as-an-anode-for-li-ion-batteries
#18
Wei Shi, Haitao Zhao, Bingan Lu
In this paper, ZnCo2O4 nanowall arrays were firstly obtained through self-assembly followed by calcination. Then atomic layer deposition was used to fabricate core-shell ZnCo2O4@TiO2 nanowall arrays (NWAs) as anode materials for lithium ion batteries (LIBs). The hierarchical nanowall array nanostructure with fast ion diffusion and electron transport at electrode/electrolyte interface, while the shell of TiO2 with excellent chemical stability can protect the ZnCo2O4 nanowall arrays from volume expansion during charge and discharge processes...
February 23, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28230458/progression-to-type-2-diabetes-and-its-effect-on-health-care-costs-in-low-income-and-insured-patients-with-prediabetes-a-retrospective-study-using-medicaid-claims-data
#19
Jun Wu, Eileen Ward, Tiffaney Threatt, Z Kevin Lu
BACKGROUND: Prediabetes is a high-risk factor for progression to diabetes. Without lifestyle changes, such as weight loss and moderate physical activity, 15%-30% of people with prediabetes are projected to develop type 2 diabetes within 5 years. Progression to diabetes increases the financial burden significantly for patients and health care systems. Populations with low socioeconomic status are associated with a higher risk of diabetes. However, knowledge is limited about the effect of transition to diabetes on future costs incurred in low-income populations...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230377/tailoring-anisotropic-li-ion-transport-tunnels-on-orthogonally-arranged-li-rich-layered-oxide-nanoplates-towards-high-performance-li-ion-batteries
#20
Ming Xu, Linfeng Fei, Wei-Bing Zhang, Tao Li, Wei Lu, Nian Zhang, Yanqing Lai, Zhian Zhang, Jing Fang, Kai Zhang, Jie Li, Haitao Huang
High-performance Li-rich layered oxide (LRLO) cathode material is appealing for next-generation Li-ion batteries owing to its high specific capacity (>300 mAh g-1). Despite intense studies in past decade, the low initial Coulombic efficiency and unsatisfactory cycling stability of LRLO still remain great challenges for its practical application. Here, we report a rational design of the orthogonally arranged {010}-oriented LRLO nanoplates with built-in anisotropic Li+ ion transport tunnels. Such a novel structure enables fast Li+ ion intercalation and deintercalation kinetics and enhanced structure stability for LRLO...
February 23, 2017: Nano Letters
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