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https://www.readbyqxmd.com/read/29145447/from-bead-to-rod-comparison-of-theories-by-measuring-translational-drag-coefficients-of-micron-sized-magnetic-bead-chains-in-stokes-flow
#1
Kaiyuan Yang, Chen Lu, Xiaodan Zhao, Ryo Kawamura
Frictional drag force on an object in Stokes flow follows a linear relationship with the velocity of translation and a translational drag coefficient. This drag coefficient is related to the size, shape, and orientation of the object. For rod-like objects, analytical solutions of the drag coefficients have been proposed based on three rough approximations of the rod geometry, namely the bead model, ellipsoid model, and cylinder model. These theories all agree that translational drag coefficients of rod-like objects are functions of the rod length and aspect ratio, but differ among one another on the correction factor terms in the equations...
2017: PloS One
https://www.readbyqxmd.com/read/29145324/a-rare-case-of-merkel-cell-carcinoma-presenting-as-a-giant-intra-thoracic-mass-a-case-report-and-review-of-the-literature
#2
Feng-Wei Kong, Miao Zhang, Heng Wang, Cun-Tao Lu, Wen-Bin Wu, Yuan-Yuan Liu
RATIONALE: Merkel cell carcinoma (MCC) is an aggressive neuroendocrine-derived cutaneous cancer. Ectopic or single metastatic MCC located in thorax is extremely rare; meanwhile, its definite management has not been elucidated yet. PATIENT CONCERNS: A 64-year-old female patient with a giant mass located in her left thorax was presented for stuffy pain of left chest for 6 months and fever for half a month. She underwent radical resection of vulvar MCC 10 years ago...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145306/dynamic-noninvasive-markers-predict-hepatocellular-carcinoma-in-chronic-hepatitis-c-patients-without-sustained-virological-response-after-interferon-based-therapy-prioritize-who-needs-urgent-direct-acting-antiviral-agents
#3
Chao-Min Huang, Tsung-Hui Hu, Kuo-Chin Chang, Po-Lin Tseng, Sheng-Nan Lu, Chien-Hung Chen, Jing-Houng Wang, Chuan-Mo Lee, Ming-Chao Tsai, Ming-Tsung Lin, Yi-Hao Yen, Chao-Hung Hung, Chung-Lung Cho, Cheng-Kun Wu
Some patients with hepatitis C virus (HCV) infections who fail to achieve sustained virological responses (SVRs) after interferon (IFN) therapy do not develop hepatocellular carcinoma (HCC). Risk stratification of these patients may help identify those who would benefit most from treatment with direct-acting antivirals (DAAs).A total of 552 HCV-infected patients with non-SVR status were enrolled. Laboratory data before and after IFN treatment were analyzed to determine the relationship of changes in serum markers with development of HCC during the 7-year study period...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145298/small-cell-lung-cancer-treated-by-radiofrequency-ablation-a-case-report
#4
Guo-Qiang Song, Fei Chen, Farong Zang, Huoquan Lu, Bin Lin
RATIONALE: The morbidity and mortality of small cell lung cancer (SCLC), an uncommon malignancy of the lung, remain high. Radiofrequency ablation (RFA) creates heat to destroy cancer cells and is usually used to treat non-SCLC, but not SCLC. PATIENT CONCERNS: An 85-year-old male presented with a 2-month history of a productive cough with white phlegm and a 2-day history of hemoptysis. Chest computed tomography revealed a mass in the right lower lobe. DIAGNOSES: An excision biopsy of the mass showed SCLC...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145289/mercury-poisoning-through-intravenous-administration-two-case-reports-with-literature-review
#5
Qiuying Lu, Zilong Liu, Xiaorui Chen
RATIONALE: Metallic mercury poisoning through intravenous injection is rare, especially for a homicide attempt. Diagnosis and treatment of the disease are challenging. PATIENT CONCERNS: A 34-year-old male presented with pyrexia, chill, fatigue, body aches, and pain of the dorsal aspect of right foot. Another case is that of a 29-year-old male who committed suicide by injecting himself metallic mercury 15 g intravenously and presented with dizzy, dyspnea, fatigue, sweatiness, and waist soreness...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145288/efficacy-of-cold-application-on-pain-during-chest-tube-removal-a-randomized-controlled-trial-a-consort-compliant-article
#6
Ling-Yu Hsieh, Yi-Rong Chen, Mei-Chun Lu
BACKGROUND: Use of analgesics is the most common method to alleviate the pain induced by chest tube removal (CTR), but patient response to medication can vary and may not be achieved complete relaxation. This study was to determine the effectiveness of cold application in combination with standard analgesic administration before CTR on CTR-induced pain. METHODS: A prospective, randomized, single-blind, sham-controlled study was conducted. In addition to the same routine care, subjects in the experimental group (n = 30) received cold application of 600-g ice packs 15 minutes before CTR, whereas subjects in the sham group (n = 30) received tap water packs...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145254/individualized-prevention-against-hypertension-based-on-traditional-chinese-medicine-constitution-theory-a-large-community-based-retrospective-strobe-compliant-study-among-chinese-population
#7
Ying Li, Xiao-Hui Li, Xin Huang, Lu Yin, Cheng-Xian Guo, Chang Liu, Yong-Mei He, Xing Liu, Hong Yuan
Traditional Chinese Medicine Constitution (TCMC) theory states that individuals with a biased TCMC are more likely to suffer from specific diseases. However, little is known regarding the influence of TCMC on susceptibility to hypertension. The aim of this study is to examine the possible relationship between TCMC and hypertension. Retrospective evaluation and observation were performed using the STROBE guidelines checklist. A large community-based cross-sectional study was conducted between 2009 and 2013 in Changsha, China...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145242/the-association-of-genetic-variants-in-chemokine-genes-with-the-risk-of-psoriasis-vulgaris-in-chinese-population-a-case-control-study
#8
Jin Zhang, Qiuhe Song, Kun Zhu, Jun Lu, Xiaogang Xiong, Fei Hao
This study aimed to investigate the influence of polymorphisms in chemokine genes, including MCP1, CCR2, and CCR5 with psoriasis vulgaris (PV) risk in a Chinese population.The genotyping of studied polymorphisms through polymerase chain reaction (PCR) and sequencing was conducted in 142 PV patients and 147 healthy controls. The genotype distribution of the polymorphisms in the control group was checked to determine whether it conformed to Hardy-Weinberg equilibrium (HWE). The genotype and allele frequencies were compared between PV patients and the healthy controls using Chi-square test...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145237/the-impact-of-the-government-health-funding-on-prescribing-behaviors-in-community-health-institutions-in-china
#9
Gang Sun, Zuxun Lu, Yong Gan, Xiaoxin Dong, Yongbin Li, Yunxia Wang, Liqing Li
Government health funding (GHF) is a cosmopolitan problem. It is especially conspicuous in China, where drug sales become a main source of medical institutions' incomes due to limited GHF. This is well known as China's "drug maintain medical institutions (DMMIs)" system which results directly in very high use of antibiotics, injections, and corticosteroids. However, few statistical data existed in China on the association between the GHF and the prevalence of inappropriate drug prescribing, despite widespread acknowledgment of its existence...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145157/bmscs-derived-mir-223-containing-exosomes-contribute-to-liver-protection-in-experimental-autoimmune-hepatitis
#10
Lu Chen, Feng-Bin Lu, Da-Zhi Chen, Jin-Lu Wu, En-de Hu, Lan-Man Xu, Ming-Hua Zheng, Hui Li, Yu Huang, Xiao-Ya Jin, Yue-Wen Gong, Zhuo Lin, Xiao-Dong Wang, Yong-Ping Chen
Autoimmune hepatitis is a chronic inflammatory disease in the liver with potential to the development of liver fibrosis. Recent evidences suggest that bone marrow derived mesenchymal stem cells (BMSCs) may exert its therapeutic activity through exosomes. Moreover, miR-223 is highly expressed in BMSCs and plays an important role in autoimmune diseases. Therefore, in this study, hepatoprotective role of BMSCs and miR-223 was investigated in both mice and hepatocytes. Liver antigen S100 was used to establish autoimmune hepatitis model in mice while LPS and ATP were used to establish cell injury model in hepatocyte...
November 13, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/29145134/comparative-analyses-of-catalytic-degradation-of-pcdd-fs-in-the-laboratory-vs-industrial-conditions
#11
Ming-Xiu Zhan, Jian-Ying Fu, Long-Jie Ji, Ivan Deviatkin, Sheng-Yong Lu
This study investigates the efficiencies and mechanisms of the catalytic degradation of polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) first, in simulated laboratory conditions and then, in a commercial municipal solid waste incineration (MSWI) plant. Five commercially available V2O5-WO3/TiO2 (VWTi) catalysts were tested. The degradation efficiency of PCDD/Fs in the simulated flue gas ranged 22.8-91.7% and was generally higher than that in the MSWI flue gas of 8.0-85.4%. The degradation efficiency of PCDD/Fs in the real flue gas of the MSWI plant was largely hindered by the complex composition of the flue gas, which could not be completely reproduced in the simulated laboratory conditions...
October 24, 2017: Chemosphere
https://www.readbyqxmd.com/read/29145047/effects-of-water-and-nitrogen-addition-on-ecosystem-respiration-across-three-types-of-steppe-the-role-of-plant-and-microbial-biomass
#12
Wei Liu, Xiaotao Lü, Wenfang Xu, Huiqiu Shi, Longyu Hou, Linghao Li, Wenping Yuan
Evaluating the regional variation of ecosystem respiration (Reco) in its response to the changes of soil water and nitrogen (N) availability is crucial for fully understanding ecosystem carbon (C) exchange and its feedbacks to global changes. Here, we examined the responses of Reco, plant community aboveground biomass (AB), microbial biomass carbon (MBC) and soil moisture (SM) to water and N addition, using intact soil monoliths from three different temperate steppes along a precipitation gradient, including meadow steppe, typical steppe, and desert steppe in northern China...
November 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29144967/a-local-rebalancing-act-leads-to-global-benefit
#13
Ju Lu, Yi Zuo
Barnes et al. (2017) reveal that in the visual cortex of sensory-deprived mice, dendritic spine enlargement correlates with recent spine loss from the same dendritic branch. Such branch-specific homeostatic plasticity highlights dendritic branches as key computational units.
November 15, 2017: Neuron
https://www.readbyqxmd.com/read/29144585/therapeutic-potential-of-low-dose-il-2-in-immune-thrombocytopenia-an-analysis-of-3-cases
#14
Jiakui Zhang, Yanjie Ruan, Xuanxuan Xu, Huiping Wang, Qianshan Tao, Jun Lu, Linhuan Xia, Qiuye Zhang, Jeffrey Wang, Yiping Wang, Zhimin Zhai
Immune thrombocytopenia (ITP) is an acquired immune-mediated disorder with regulatory T cells (Tregs) reduction. Recent studies have shown that low-dose interleukin-2 can preferentially induce regulatory T cell expansion in vivo, and therefore offers a therapeutic strategy against immune thrombocytopenia. We have demonstrated in a previous study that Tregs and platelet counts significantly improve in an adult with ITP following low-dose IL-2 treatment. Here we report the efficacy of low-dose interleukin-2 in another three adults with immune thrombocytopenia who failed the first-line treatment...
November 16, 2017: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/29144570/lncapc-drives-wnt-%C3%AE-catenin-activation-and-liver-tic-self-renewal-through-ezh2-mediated-apc-transcriptional-inhibition
#15
Xiaomin Fu, Jizhen Lin, Fujun Qin, Zihe Yang, Yuechao Ding, Yong Zhang, Lu Han, Xiaoyan Zhu, Qinxian Zhang
Liver tumor initiating cells (TICs), a small subset cells in tumor bulk, are responsible for liver tumor initiation, metastasis and relapse. However, the regulatory mechanism of liver TICs remains largely unknown. Here we found a long noncoding RNA lncAPC, locating near from APC locus, was highly expressed in liver cancer and liver TICs. LncAPC was required for liver TIC self-renewal. Silencing and overexpressing lncAPC showed impaired and enhanced sphere formation capacity of liver TICs, respectively. By recruiting EZH2 to APC promoter, LncAPC inhibits APC transcription and thus drives the activation of Wnt/β-catenin signaling...
November 16, 2017: Molecular Carcinogenesis
https://www.readbyqxmd.com/read/29144425/selective-laser-sintering-of-porous-silica-enabled-by-carbon-additive
#16
Shuai Chang, Liqun Li, Li Lu, Jerry Ying Hsi Fuh
The aim of this study is to investigate the possibility of a freeform fabrication of porous ceramic parts through selective laser sintering (SLS). SLS was proposed to manufacture ceramic green parts because this additive manufacturing technique can be used to fabricate three-dimensional objects directly without a mold, and the technique has the capability of generating porous ceramics with controlled porosity. However, ceramic printing has not yet fully achieved its 3D fabrication capabilities without using polymer binder...
November 16, 2017: Materials
https://www.readbyqxmd.com/read/29144385/preparation-and-characterization-of-cellulose-triacetate-as-support-for-lecitase-ultra-immobilization
#17
Francielle Batista da Silva, Wilson Galvão de Morais Júnior, Cleuzilene Vieira da Silva, Andressa Tironi Vieira, Antônio Carlos Ferreira Batista, Anízio Márcio de Faria, Rosana Maria Nascimento Assunção
The use of polymers as supports for enzyme immobilization is a strategy that enables to remove the enzymes from a chemical reaction and improve their efficiency in catalytic processes. In this work, cellulose triacetate (CTA) was used for physical adsorption of phospholipase Lecitase ultra (LU). CTA is more hydrophobic than cellulose, shows good performance in the lipases immobilization being a good candidate for immobilization of phospholipases. We investigated the immobilization of LU in CTA, the stability of the immobilized enzyme (CTA-LU) and the performance of CTA-LU using soybean oil as a substrate...
November 16, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29144283/large-purcell-enhancement-with-efficient-one-dimensional-collection-via-coupled-nanowire-nanorod-system
#18
Xueke Duan, Juanjuan Ren, Fan Zhang, He Hao, Guowei Lu, Qihuang Gong, Ying Gu
Combining the advantages of both gap surface plasmons and evanescent waves, we demonstrate simultaneously large Purcell enhancement and efficient one- dimensional collection of photons at subwavelength scale in the coupled nanowire- nanorod system. The spontaneous emission can be enhanced by thousands of times based on the excitation of gap surface plasmons with strongly localized electromagnetic field. Emitted photons are directly collected by subwavelength-confined evanescent modes and guided along the nanowire...
November 16, 2017: Nanotechnology
https://www.readbyqxmd.com/read/29144059/association-between-smoking-and-glycemic-control-in-diabetic-patients-results-from-the-reaction-study
#19
Kui Peng, Gang Chen, Chao Liu, Yiming Mu, Zhen Ye, Lixin Shi, Jiajun Zhao, Lulu Chen, Qiang Li, Tao Yang, Li Yan, Qin Wan, Shengli Wu, Guixia Wang, Zuojie Luo, Xulei Tang, Yanan Huo, Zhengnan Gao, Qing Su, Youmin Wang, Guijun Qin, Huacong Deng, Xuefeng Yu, Feixia Shen, Li Chen, Liebin Zhao, Yu Xu, Min Xu, Yuhong Chen, Jieli Lu, Lin Lin, Rui Du, Meng Dai, Mian Li, Tiange Wang, Zhiyun Zhao, Di Zhang, Yufang Bi, Donghui Li, Weiqing Wang, Guang Ning
BACKGROUND: A number of primary studies suggested that active smoking could be independently associated with incident diabetes. However less is known about the impact of active smoking and smoking cessation on glycemic control in patients with diabetes. We aimed to evaluate the associations of active smoking and smoking cessation with glycemic control in diabetic patients. METHODS: This is a cross-sectional study of 10,551 man and 15,297 women with diabetes from the Risk Evaluation of cAncers in Chinese diabeTic Individuals: a lONgitudinal (REACTION) study...
November 16, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/29144020/combining-click-sulfur-vi-fluoride-exchange-with-photoiniferters-a-facile-fast-and-efficient-strategy-for-postpolymerization-modification
#20
Peixi Wang, Yishi Dong, Xiaowen Lu, Zhaoqiang Wu, Hong Chen
"Click" type reactions represent the currently most prevalent postpolymerization strategy for the preparation of functional polymeric materials. Herein, a novel photoiniferter agent 4-(fluorosulfonyl)benzyl diethylcarbamodithioate (FSB-DECT) containing both dithiocarbamates and sulfonyl fluoride moieties is developed to act as both photoinitiator and click sulfur(VI)-fluoride exchange (SuFEx) agent. The photopolymerization behavior of FSB-DECT is demonstrated via standard photoiniferter-mediated polymerization for various types of monomer including N-isopropylacrylamide (NIPAAm), glycidyl methacrylate, and vinyl acetate (VAc)...
November 16, 2017: Macromolecular Rapid Communications
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