keyword
https://read.qxmd.com/read/38615021/multi-center-study-on-mortality-in-children-and-adults-with-sickle-cell-anemia-risk-factors-and-causes-of-death
#21
MULTICENTER STUDY
Salam Alkindi, Salma Al-Jadidi, Safa Al-Adawi, Refaat Abdullah Elsadek, Ali Al Madhani, Maryam Al-Nabhani, Anil V Pathare
Sickle cell disease (SCD) is a major public health burden worldwide with increasing morbidity and mortality. The study evaluates the risk factors associated with mortality in SCD patients, between the years 2006 and 2020 at three hospitals in Oman. The analysis includes clinical manifestations, haematological, biochemical, and radiological parameters, use of antibiotics, and blood and exchange transfusions. Our cohort included 123 patients (82 males, 41 females), with a median age of 27 (Interquartile Range 21-35 years)...
April 13, 2024: Scientific Reports
https://read.qxmd.com/read/38614796/chest-ct-features-and-functional-correlates-of-covid-19-at-3-months-and-12-months-follow-up
#22
JOURNAL ARTICLE
Kartik Kumar, Ratnaprashanthika Ratnakumar, Simon M Collin, Luis C Berrocal-Almanza, Piera Ricci, Mustafa Al-Zubaidy, Robina K Coker, Meg Coleman, Sarah L Elkin, Patrick Mallia, Jamilah Meghji, Clare Ross, Georgina K Russell, Katie Ward, Melissa Wickremasinghe, Sarah Sheard, Susan J Copley, Onn Min Kon
Long-term pulmonary sequelae of Coronavirus 2019 (COVID-19) remain unclear. Thus, we aimed to establish post-COVID-19 temporal changes in chest computed tomography (CT) features of pulmonary fibrosis and to investigate associations with respiratory symptoms and physiological parameters at 3 and 12 months' follow-up. Adult patients who attended our initial COVID-19 follow-up service and developed chest CT features of interstitial lung disease, in addition to cases identified using British Society of Thoracic Imaging codes, were evaluated retrospectively...
September 2023: Clinical Medicine: Journal of the Royal College of Physicians of London
https://read.qxmd.com/read/38611694/opportunistic-screening-for-acute-vertebral-fractures-on-a-routine-abdominal-or-chest-computed-tomography-scans-using-an-automated-deep-learning-model
#23
JOURNAL ARTICLE
Ye Rin Kim, Yu Sung Yoon, Jang Gyu Cha
OBJECTIVES: To develop an opportunistic screening model based on a deep learning algorithm to detect recent vertebral fractures in abdominal or chest CTs. MATERIALS AND METHODS: A total of 1309 coronal reformatted images (504 with a recent fracture from 119 patients, and 805 without fracture from 115 patients), from torso CTs, performed from September 2018 to April 2022, on patients who also had a spine MRI within two months, were included. Two readers participated in image selection and manually labeled the fractured segment on each selected image with Neuro-T (version 2...
April 8, 2024: Diagnostics
https://read.qxmd.com/read/38609851/disseminated-cryptococcus-neoformans-infection-involving-multiple-bones-and-lung-in-an-immunocompetent-patient-a-case-report
#24
JOURNAL ARTICLE
Yang-Ming Lee, Yuag-Meng Liu, Tsung-Chia Chen
BACKGROUND: Cryptococcal osteomyelitis is a rare and potentially serious condition, typically encountered in individuals with compromised immune systems. This case underscores the unusual occurrence of disseminated Cryptococcosis in an immunocompetent person, involving multiple bones and lungs, with Cryptococcus neoformans identified as the causative agent. CASE PRESENTATION: An Indonesian man, previously in good health, presented with a chief complaint of successive multiple bone pain lasting for more one month, without any prior history of trauma...
April 12, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38609053/coronary-artery-calcium-assessment-on-non-gated-chest-ct-to-optimize-pre-operative-cardiac-screening-in-liver-transplantation
#25
JOURNAL ARTICLE
Roos A Groen, Fei Lynn Barbero, Susan E Fischer, Paul R M van Dijkman, Jeroen J Bax, Maarten E Tushuizen, J Wouter Jukema, Minneke J Coenraad, Michiel A de Graaf
BACKGROUND: Guidelines recommend standard pre-operative cardiac screening in all liver transplantation (LT) recipients, despite the relatively low prevalence of obstructive coronary artery disease. Most LT recipients often have non-gated computed tomography (CT) performed of the chest and abdomen. This study evaluated the ability of coronary artery calcification (CAC) assessment on consecutively available scans, to identify a selection of low-risk patients, in whom further cardiac imaging can be safely withheld...
April 10, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38607727/a-user-friendly-deep-learning-application-for-accurate-lung-cancer-diagnosis
#26
JOURNAL ARTICLE
Duong Thanh Tai, Nguyen Tan Nhu, Pham Anh Tuan, Abdelmoneim Suleiman, Hiba Omer, Zahra Alirezaei, David Bradley, James C L Chow
BACKGROUND: Accurate diagnosis and subsequent delineated treatment planning require the experience of clinicians in the handling of their case numbers. However, applying deep learning in image processing is useful in creating tools that promise faster high-quality diagnoses, but the accuracy and precision of 3-D image processing from 2-D data may be limited by factors such as superposition of organs, distortion and magnification, and detection of new pathologies. The purpose of this research is to use radiomics and deep learning to develop a tool for lung cancer diagnosis...
April 9, 2024: Journal of X-ray Science and Technology
https://read.qxmd.com/read/38607459/oxygenation-and-ventilation-during-prolonged-experimental-cardiopulmonary-resuscitation-with-either-continuous-or-30-2-compression-to-ventilation-ratios-together-with-10%C3%A2-cmh-2-0-positive-end-expiratory-pressure
#27
JOURNAL ARTICLE
Jukka Kopra, Erik Litonius, Pirkka T Pekkarinen, Merja Laitinen, Juho A Heinonen, Luca Fontanelli, Markus B Skrifvars
BACKGROUND: In refractory out-of-hospital cardiac arrest, the patient is commonly transported to hospital with mechanical continuous chest compressions (CCC). Limited data are available on the optimal ventilation strategy. Accordingly, we compared arterial oxygenation and haemodynamics during manual asynchronous continuous ventilation and compressions with a 30:2 compression-to-ventilation ratio together with the use of 10 cmH2 O positive end-expiratory pressure (PEEP). METHODS: Intubated and anaesthetized landrace pigs with electrically induced ventricular fibrillation were left untreated for 5 min (n = 31, weight ca...
April 12, 2024: Intensive Care Medicine Experimental
https://read.qxmd.com/read/38606154/case-report-efficacy-of-icotinib-treatment-in-lung-adenocarcinoma-with-esophageal-squamous-cell-carcinoma-a-rare-case-of-double-primary-malignant-tumors
#28
Min Deng, Xiaoqing Li, Honghao Mu, Man Wei, Lan Sun
BACKGROUND: Lung adenocarcinoma with esophageal squamous cell carcinoma is rare and the prognosis is poor, therefore there is an urgent need to improve this situation. The objective of this study was to explore the effect of first-generation tyrosine kinase inhibitors (TKIs) in the patient of the double primary malignant tumors. CASE REPORT: We report a case of lung adenocarcinoma with esophageal squamous cell carcinoma treated by icotininb after five-year follow-up...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38605533/persistent-fever-after-coronavirus-disease-2019-in-liver-kidney-transplant-recipient
#29
JOURNAL ARTICLE
Caroline E Mullis, Madeleine Heldman, Nathan C Bahr, Grace Y Minamoto, Yoram A Puius, Maricar Malinis
In this case, a 64-year-old male with a history of simultaneous orthotopic liver transplant and cadaveric renal transplant presented five years prior presented with persistent fevers two days after a positive SARS-CoV-2 nasal PCR. A CT scan of the chest on hospital day nine revealed innumerable 1-2 mm nodules in a miliary pattern throughout the lung. (1,3)-β-D-glucan on hospital day 11 was 133 pg/mL. In this article, the approach, diagnostic and management strategies for patients with persistent fevers after diagnosis of COVID-19 in a transplant recipient are discussed...
April 11, 2024: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://read.qxmd.com/read/38604190/patient-derived-pixelprint-phantoms-for-evaluating-clinical-imaging-performance-of-a-deep-learning-ct-reconstruction-algorithm
#30
JOURNAL ARTICLE
Jessica Yunyun Im, Sandra Halliburton, Kai Mei, Amy E Perkins, Eddy Wong, Leonid Roshkovan, Olivia F Sandvold, Leening P Liu, Grace J Gang, Peter B Noël
Objective
Deep learning reconstruction (DLR) algorithms exhibit object-dependent resolution and noise performance. Thus, traditional geometric CT phantoms cannot fully capture the clinical imaging performance of DLR. This study uses a patient-derived 3D-printed PixelPrint lung phantom to evaluate a commercial DLR algorithm across a wide range of radiation dose levels.

Method
The lung phantom used in this study is based on a patient chest CT scan containing ground glass opacities and was fabricated using PixelPrint 3D-printing technology...
April 11, 2024: Physics in Medicine and Biology
https://read.qxmd.com/read/38604185/deep-learning-for-high-resolution-dose-prediction-in-high-dose-rate-brachytherapy-for-breast-cancer-treatment
#31
JOURNAL ARTICLE
Sébastien Quetin, Boris Bahoric, Farhad Maleki, Shirin A Enger
Monte Carlo (MC) simulations are the benchmark for accurate radiotherapy dose calculations, notably in patient-specific high dose rate brachytherapy (HDR BT), in cases where considering tissue heterogeneities is critical. However, the lengthy computational time limits the practical application of MC simulations. Prior research used Deep Learning (DL) for dose prediction as an alternative to MC simulations. While accurate dose predictions akin to MC were attained, GPU limitations constrained these predictions to large voxels of 3mm × 3mm × 3mm...
April 11, 2024: Physics in Medicine and Biology
https://read.qxmd.com/read/38602207/-when-eosinophilia-is-not-only-a-marker-of-asthma-%C3%A2
#32
Jalal Hamdi, Vincent Heinen, Frédéric Fiévet, Majdouline El Moussaoui, Renaud Louis, Florence Schleich
We report the case of a patient who has been hospitalized for dyspnea. Investigations revealed airway obstruction, eosinophilia, elevated IgE and elevated exhaled nitric oxide. Patient improved with oral corticosteroids (OCS). However, the patient presented two exacerbations requiring OCS during the next twelve months. Chest CT scan revealed two multiloculated parenchymal lesions. Lab test was positive for Echinococcus and Western-Blot confirmed infection with Echinococcus granulosus. Bronchoalveolar lavage confirmed the presence of 6 % eosinophils...
April 2024: Revue Médicale de Liège
https://read.qxmd.com/read/38601042/a-case-report-on-pheochromocytoma-mimicking-as-fulminant-myocarditis-a-diagnostic-challenge
#33
Yanwei Cheng, Ning Ding, Longan Wang, Lijie Qin
We present an exceptional case of a 53-year-old female, initially misdiagnosed with fulminant myocarditis, but later correctly diagnosed with pheochromocytoma. The presentation of the patient included a spectrum of symptoms such as headache, chest discomfort, palpitations, and dyspnea, following the intake of Domperidone. Two weeks prior to admission, the patient had experienced episodes of diarrhea and a low-grade fever. Unresolved symptoms and an unmanageable surge in blood pressure despite comprehensive fulminant myocarditis treatment prompted further investigation...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38600864/covid-19-diagnostic-prediction-on-chest-ct-scan-images-using-hybrid-quantum-classical-convolutional-neural-network
#34
JOURNAL ARTICLE
Haorong Zhao, Xing Deng, Haijian Shao, Yingtao Jiang
Notwithstanding the extensive research efforts directed towards devising a dependable approach for the diagnosis of coronavirus disease 2019 (COVID-19), the inherent complexity and capriciousness of the virus continue to pose a formidable challenge to the precise identification of affected individuals. In light of this predicament, it is essential to devise a model for COVID-19 prediction utilizing chest computed tomography (CT) scans. To this end, we present a hybrid quantum-classical convolutional neural network (HQCNN) model, which is founded on stochastic quantum circuits that can discern COVID-19 patients from chest CT images...
April 2024: Journal of Biomolecular Structure & Dynamics
https://read.qxmd.com/read/38600678/type-a-aortic-dissection-after-coronary-artery-bypass-grafting
#35
JOURNAL ARTICLE
Vusal Hajiyev, Murad Qubadov, Leyla Maharramova, Gulnaz Dadashova, Asiman Hasanov
BACKGROUND Aortic dissection is rare after coronary artery bypass grafting (CABG). It is a potentially fatal complication of cardiac surgery. Reoperation may pose problems with thoracotomy, adhesiolysis, and myocardial protection. No standard treatment guidelines exist for chronic aortic dissection after CABG. We present a case of chronic type A aortic dissection after cardiac surgery, which was successfully treated. CASE REPORT A 65-year-old female patient presented with a medical background of hypertension, type 2 diabetes mellitus, and hyperlipidemia...
April 11, 2024: American Journal of Case Reports
https://read.qxmd.com/read/38599810/-diffuse-thickening-of-bronchial-walls-with-multiple-nodular-mucosal-protrusions
#36
JOURNAL ARTICLE
W Y Zhu, Y H Li, T Zhang, M Peng, R E Feng, J H Shi
A 58-year-old woman presented with a six-month history of nasal congestion, sore throat and cough, and a five-month history of dyspnea. She had a history of xerostomia for one year. On examination, the bilateral submandibular gland and parotid glands were enlarged. Parotid and anterior cervical lymph nodes were palpable. There were rales in both lungs. The rest of the physical examination was unremarkable. Sialographic analysis showed normal caliber in the main duct, stenosis in secondary ducts, and dilation in the proximal ducts...
April 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38599764/a-52-year-old-woman-with-dysarthria-ataxia-xanthelasmas-and-miliary-pulmonary-nodules
#37
Athena Huynh, Collin Pryma, Heather McPhaden, Karl-Christopher Yared, Yilin Zhang, Katie Beadon, Tony Ng, Luke Y C Chen
A 52-year-old woman with no significant medical history was referred to our hospital for expedited workup of progressive dysarthria and ataxia over the past year. Prior CT angiography of the head and neck showed no relevant neurologic findings but did reveal miliary lesions in the lung apices, which was later confirmed via dedicated CT chest scan (Fig 1). Review of systems was negative for any respiratory, constitutional, or rheumatologic symptoms, except for new xanthelasma-like lesions over her forehead. She previously had smoked with 20 pack-years and had no TB risk factors...
April 2024: Chest
https://read.qxmd.com/read/38599756/an-88-year-old-woman-with-pneumothorax-and-black-pleural-effusion
#38
Shota Takenaka, Masayo Yoshimura, Yoshiaki Kinoshita, Takuhide Utsunomiya, Hisako Kushima, Satoshi Nimura, Hiroshi Ishii
An 88-year-old woman was admitted to our hospital with the sudden onset of dyspnea after eating. The patient had undergone nephrectomy for a left renal tumor 24 years previously. The patient had been prescribed ferrous citrate for iron-deficiency anemia. She complained of appetite loss a few days before admission but had no abdominal pain. CT scan showed no abnormalities in the lungs but a mass in the liver.
April 2024: Chest
https://read.qxmd.com/read/38599262/ct-derived-vertebral-bone-mineral-density-is-a-useful-biomarker-to-predict-covid-19-outcome
#39
JOURNAL ARTICLE
Shuhei Azekawa, Tomoki Maetani, Shotaro Chubachi, Takanori Asakura, Naoya Tanabe, Yusuke Shiraishi, Ho Namkoong, Hiromu Tanaka, Takashi Shimada, Takahiro Fukushima, Shiro Otake, Kensuke Nakagawara, Mayuko Watase, Hideki Terai, Mamoru Sasaki, Soichiro Ueda, Yukari Kato, Norihiro Harada, Shoji Suzuki, Shuichi Yoshida, Hiroki Tateno, Yoshitake Yamada, Masahiro Jinzaki, Toyohiro Hirai, Yukinori Okada, Ryuji Koike, Makoto Ishii, Akinori Kimura, Seiya Imoto, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga
The low vertebral bone computed tomography (CT) Hounsfield unit values measured on CT scans reflect low bone mineral density (BMD) and are known as diagnostic indicators for osteoporosis. The potential prognostic significance of low BMD defined by vertebral bone CT values for the coronavirus disease 2019 (COVID-19) remains unclear. This study aimed to assess the impact of BMD on the clinical outcome in Japanese patients with COVID-19 and evaluate the association between BMD and critical outcomes, such as high-flow nasal cannula, non-invasive and invasive positive pressure ventilation, extracorporeal membrane oxygenation, or death...
April 8, 2024: Bone
https://read.qxmd.com/read/38599187/age-based-diagnostic-reference-levels-and-achievable-doses-for-pediatric-ct-a-survey-in-shanghai-china
#40
JOURNAL ARTICLE
Fanqiaochu Yang, Linfeng Gao
Computed tomography (CT) is extensively utilized in medical diagnostics due to its notable radiographic superiority. However, the cancer risk associated with CT examinations, particularly in children, is of significant concern. The assessment of cancer risk relies on the radiation dose to examinees. Diagnostic reference levels (DRLs) and achievable doses (ADs) were used to assess the level of radiation dose in CT examinations widely. Although the national DRLs of pediatric CT have been explored in China, few local DRLs at the city level have been assessed...
April 10, 2024: Journal of Radiological Protection: Official Journal of the Society for Radiological Protection
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