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https://www.readbyqxmd.com/read/27238811/-in-process-citation
#1
José Luis González-Montesinos, Jesús Gustavo Ponce-González, Davinia Vicente-Campos, José López-Chicharro, Jorge Del Rosario Fernández-Santos, Carmen Vaz-Pardal, José Luis Costa-Sepúlveda, Julio Conde-Caveda, José Castro-Piñero
Introducción y objetivos: un dispositivo llamado FeelBreathe ® (FB) se ha diseñado, desarrollado y patentado para el entrenamiento de la musculatura inspiratoria (IMT). Para examinar los efectos de FB en la ventilación pulmonar y el intercambio gaseoso durante el ejercicio, se tomaron medidas de 27 voluntarios varones sanos entrenados (edad: 32,5 ± 7,2 años). Métodos: al inicio del estudio se midieron tanto la presión inspiratoria máxima estática (PIM) y la capacidad pulmonar mediante espirometría...
2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/24685597/adjusting-the-dose-of-tamoxifen-in-patients-with-early-breast-cancer-and-cyp2d6-poor-metabolizer-phenotype
#2
Eduardo Martinez de Dueñas, Enrique Ochoa Aranda, Isabel Blancas Lopez-Barajas, Teresa Ferrer Magdalena, Fernando Bandrés Moya, Luis Miguel Chicharro García, José A Gómez Capilla, Mercedes Zafra Ceres, Tomás de Haro, Regina Romero Llorens, Carlos Ferrer Albiach, Rafael Ferriols Lisart, Dolores Chover Lara, Angela López Rodríguez, Javier Munárriz Ferrandis, Santiago Olmos Antón
BACKGROUND: CYP2D6 is a key enzyme in tamoxifen metabolism, transforming it into its main active metabolite, endoxifen. Poor CYP2D6 metabolizers (PM) have lower endoxifen plasma concentrations and possibly benefit less from treatment with tamoxifen. We evaluated tamoxifen dose adjustment in CYP2D6 PM patients in order to obtain plasma concentrations of endoxifen comparable to patients with extensive CYP2D6 metabolism (EM). PATIENTS AND METHODS: Comprehensive CYP2D6 genotyping and plasma tamoxifen metabolite concentrations were performed among 249 breast cancer patients in adjuvant treatment with tamoxifen...
August 2014: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/24553907/heart-rate-recovery-normality-data-recorded-in-response-to-a-maximal-exercise-test-in-physically-active-men
#3
Davinia Vicente-Campos, Aurora Martín López, María Jesús Nuñez, Jose López Chicharro
BACKGROUND: Despite a growing clinical interest in determining the heart rate recovery (HRR) response to exercise, the limits of a normal HRR have not yet been well established. PURPOSE: This study was designed to examine HRR following a controlled maximal exercise test in healthy, physically active adult men. METHODS: The subjects recruited (n = 789) performed a maximal stress test on a treadmill. HRR indices were calculated by subtracting the first and third minute heart rates (HRs) during recovery from the maximal HR obtained during stress testing and designated these as HRR-1 and HRR-3, respectively...
June 2014: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/24513185/antiprotozoan-lead-discovery-by-aligning-dry-and-wet-screening-prediction-synthesis-and-biological-assay-of-novel-quinoxalinones
#4
Miriam A Martins Alho, Yovani Marrero-Ponce, Stephen J Barigye, Alfredo Meneses-Marcel, Yanetsy Machado Tugores, Alina Montero-Torres, Alicia Gómez-Barrio, Juan J Nogal, Rory N García-Sánchez, María Celeste Vega, Miriam Rolón, Antonio R Martínez-Fernández, José A Escario, Facundo Pérez-Giménez, Ramón Garcia-Domenech, Norma Rivera, Ricardo Mondragón, Mónica Mondragón, Froylán Ibarra-Velarde, Atteneri Lopez-Arencibia, Carmen Martín-Navarro, Jacob Lorenzo-Morales, Maria Gabriela Cabrera-Serra, Jose Piñero, Jan Tytgat, Roberto Chicharro, Vicente J Arán
Protozoan parasites have been one of the most significant public health problems for centuries and several human infections caused by them have massive global impact. Most of the current drugs used to treat these illnesses have been used for decades and have many limitations such as the emergence of drug resistance, severe side-effects, low-to-medium drug efficacy, administration routes, cost, etc. These drugs have been largely neglected as models for drug development because they are majorly used in countries with limited resources and as a consequence with scarce marketing possibilities...
March 1, 2014: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/24334874/prospective-urodynamic-model-for-prediction-of-urinary-incontinence-after-robot-assisted-radical-prostatectomy
#5
Ovidiu-Spiru Barnoiu, Emilio Garcia Galisteo, Francisco Baron Lopez, Raul Vozmediano Chicharro, Jorge Soler Martinez, Jose Maria Del Rosal Samaniego, Javier Machuca Santacruz, Victor Baena Gonzalez
OBJECTIVES: To assess the preoperative urodynamic predictors of urinary incontinence (UI) 1 year after robot-assisted radical prostatectomy (RARP) and to design a nomogram capable of predicting its occurrence. MATERIALS AND METHODS: Our prospective study included 58 previously continent patients who underwent RARP, in most cases, bilateral nerve-sparing and bladder neck preservation. A urodynamic examination including a urethral pressure profile was performed preoperatively...
2014: Urologia Internationalis
https://www.readbyqxmd.com/read/24281224/design-and-validation-of-a-prehospital-stroke-scale-to-predict-large-arterial-occlusion-the-rapid-arterial-occlusion-evaluation-scale
#6
Natalia Pérez de la Ossa, David Carrera, Montse Gorchs, Marisol Querol, Mònica Millán, Meritxell Gomis, Laura Dorado, Elena López-Cancio, María Hernández-Pérez, Vicente Chicharro, Xavier Escalada, Xavier Jiménez, Antoni Dávalos
BACKGROUND AND PURPOSE: We aimed to develop and validate a simple prehospital stroke scale to predict the presence of large vessel occlusion (LVO) in patients with acute stroke. METHODS: The Rapid Arterial oCclusion Evaluation (RACE) scale was designed based on the National Institutes of Health Stroke Scale (NIHSS) items with a higher predictive value of LVO on a retrospective cohort of 654 patients with acute ischemic stroke: facial palsy (scored 0-2), arm motor function (0-2), leg motor function (0-2), gaze (0-1), and aphasia or agnosia (0-2)...
January 2014: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/24150633/effects-of-vibration-training-and-detraining-on-balance-and-muscle-strength-in-older-adults
#7
Pedro J Marín, Aurora Martín-López, Davinia Vicente-Campos, Mt Angulo-Carrere, Teresa García-Pastor, Nuria Garatachea, José L Chicharro
The purpose of this study was to analyze the effects of 2 days/week versus 4 days/week of Whole Body Vibration (WBV) during eight weeks of WBV training on health-related quality of life (SF-36), balance and lower body strength, as well as short-term detraining (3 weeks) on balance and lower body strength among older adults. Thirty-four older adults were randomly assigned to a control group (Control; n = 11) or to one of the vibration training groups: WBV 2 days/week (WBV_2d; n = 11) or WBV 4 days/week (WBV_4d; n = 12)...
2011: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/23478700/study-of-hyperglycemia-in-non-critically-ill-patients-receiving-parenteral-nutrition-incidence-and-risk-factors
#8
J M Llop, E Leiva, J Mateu-de Antonio, D Berlana, M Badia, T Casasín, M Miana, M Pons, M Maroto, L Chicharro, E López-Suñé, E Díaz-Munio, D Sevilla, I Martínez, M Vitales, M T Casajuana, M A Bobis
BACKGROUND: The objectives of our study on non-critically ill patients receiving parenteral nutrition (PN) are to assess the incidence of hyperglycemia, the risk factors associated to its development and its influence in patient's evolution. METHODS: A multicentric prospective observational study was performed in 9 hospitals. Four multivariate studies were developed to study the temporal risk in the occurrence of hyperglycemia (endpoint), intensive care unit (ICU) admission, length of stay (LOS) and death...
September 2012: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/23207744/comprehensive-prediction-model-of-urinary-incontinence-one-year-following-robot-assisted-radical-prostatectomy
#9
Ovidiu-Spiru Barnoiu, Francisco Baron Lopez, Emilio Garcia Galisteo, Jorge Soler Martinez, Raul Vozmediano Chicharro, Jose Maria Del Rosal Samaniego, Javier Machuca Santacruz, Pablo Navarro Vilchez, Javier Sanchez Luque, Carlos Bautista Vidal, Pablo Gomez Lechuga, Victor Baena Gonzalez
OBJECTIVES: Urinary incontinence (UI) still remains one of the major functional complications after robot-assisted radical prostatectomy (RARP). As the cause for UI is multifactorial, it is quite difficult to make a prediction preoperatively. Considering intraoperative and postoperative risk factors, besides the preoperative ones, we designed an incontinence prediction model, administered 1 month after the surgery, in order to identify incontinent patients at 1 year. PATIENTS AND METHODS: We retrospectively reviewed 244 patients who underwent RARP at our institution...
2013: Urologia Internationalis
https://www.readbyqxmd.com/read/22158143/acute-effects-of-whole-body-vibration-on-neuromuscular-responses-in-older-individuals-implications-for-prescription-of-vibratory-stimulation
#10
RANDOMIZED CONTROLLED TRIAL
Pedro J Marín, Azael J Herrero, David García-López, Matthew R Rhea, José López-Chicharro, Javier González-Gallego, Nuria Garatachea
The aim of this study was to analyze surface electromyography activity (sEMG) and rating of perceived exertion (RPE) responses in different muscles while standing on a vibrating platform producing oscillations of different frequencies and amplitudes. Twenty community-dwelling older adults (79.6 ± 3.2 years) took part in the research. Subjects were exposed to 12 different vibration treatments of 15 seconds separated by 1 minute of rest in random order to check the influence of frequency (25, 35, and 45 Hz) and amplitude (1 mm [low] and 3...
January 2012: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/21242466/plantar-pressures-in-children-with-and-without-sever-s-disease
#11
Ricardo Becerro de Bengoa Vallejo, Marta Elena Losa Iglesias, David Rodríguez Sanz, Juan Carlos Prados Frutos, Paloma Salvadores Fuentes, José López Chicharro
BACKGROUND: a case-control study was conducted to compare static plantar pressures and distribution of body weight across the two lower limbs, as well as the prevalence of gastrocnemius soleus equinus, in children with and without calcaneal apophysitis (Sever's disease). METHODS: the participants were 54 boys enrolled in a soccer academy, of which eight were lost to follow-up. Twenty-two boys with unilateral Sever's disease comprised the Sever's disease group and 24 healthy boys constituted a control group...
January 2011: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/21083695/patterns-of-physical-activity-in-spanish-children-a-descriptive-pilot-study
#12
MULTICENTER STUDY
S Aznar, P J Naylor, P Silva, M Pérez, T Angulo, M Laguna, M T Lara, J López-Chicharro
BACKGROUND: The majority of Spanish adults and children do not engage in enough physical activity to be beneficial for health. There is a need for objective and accurate assessment of the proportion of children meeting the physical activity recommendation for health. Assessing patterns of physical activity both between days (during weekdays and weekend days) and within days is of interest to improve our understanding of the variation in Spanish children's physical activity and to provide efficient intervention programmes...
May 2011: Child: Care, Health and Development
https://www.readbyqxmd.com/read/20215367/epidemiological-characteristics-and-diagnostic-approach-in-patients-admitted-to-the-emergency-room-for-transient-loss-of-consciousness-group-for-syncope-study-in-the-emergency-room-gesinur-study
#13
MULTICENTER STUDY
Gonzalo Baron-Esquivias, Jesús Martínez-Alday, Alfonso Martín, Angel Moya, Roberto García-Civera, M Paz López-Chicharro, María Martín-Mendez, Carmen del Arco, Pedro Laguna
AIMS: To assess the clinical presentation and acute management of patients with transient loss of consciousness (T-LOC) in the emergency department (ED). METHODS AND RESULTS: A multi-centre prospective observational study was carried out in 19 Spanish hospitals over 1 month. The patients included were > or =14 years old and were admitted to the ED because of an episode of T-LOC. Questionnaires and corresponding electrocardiograms (ECGs) were reviewed by a Steering Committee (SC) to unify diagnostic criteria, evaluate adherence to guidelines, and diagnose correctly the ECGs...
June 2010: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/19564761/effectiveness-of-the-physical-therapy-godelive-denys-struyf-method-for-nonspecific-low-back-pain-primary-care-randomized-control-trial
#14
RANDOMIZED CONTROLLED TRIAL
María José Díaz Arribas, Mabel Ramos Sánchez, Pedro Pardo Hervás, José López Chicharro, Teresa Angulo Carreré, Paloma Ortega Molina, Paloma Astasio Arbiza
STUDY DESIGN: A simple blind, random controlled clinical trial. OBJECTIVE: To assess the effectiveness of physiotherapy treatment based on the muscular and articular chains Godelive Denys-Struyf (GDS) method for nonspecific low back pain (LBP) in primary care. SUMMARY OF BACKGROUND DATA: Despite a systematic review by the European COST ACTION B13 "Low back pain: guidelines for its management," there are still many unresolved questions regarding the effectiveness of the different physical therapy treatments used for LBP...
July 1, 2009: Spine
https://www.readbyqxmd.com/read/18381002/-specialized-home-care-of-medical-diseases-in-an-urban-tertiary-university-hospital-coordination-between-the-medical-services-of-the-hospital-and-the-primary-health-care
#15
A San José Laporte, J Pérez López, C Alemán Llansó, E Rodríguez González, L Chicharro Serrano, F X Jiménez Moreno, I Ligüerre Casals, M C Vélez Miranda, M Vilardell Tarrés
INTRODUCTION: The experience of an urban Tertiary University Hospital in the design and implementation of Hospital at Home Program (HaHP) integrated in a Department of Internal Medicine and highly coordinated with Medical Services of the Hospital and the Primary Health Care, that contemplates the like main objectives of the promotion of specialized home care medical diseases and the improvement of the coordination with the primary health care. PATIENTS AND METHOD: Systematic collection in all the patients admitted between April 2006 and March 2007 in the HaHP of the following variables: age, gender, service of origin, main diagnosis, Barthel and Charlson index, number of visits per day to doctors and nurses, destination on discharge and medical team...
April 2008: Revista Clínica Española
https://www.readbyqxmd.com/read/18321614/immunogenicity-of-hsp-70-kmp-11-and-pfr-2-leishmanial-antigens-in-the-experimental-model-of-canine-visceral-leishmaniasis
#16
Eugenia Carrillo, Martín Crusat, Javier Nieto, Carmen Chicharro, Maria del Carmen Thomas, Enrique Martínez, Basilio Valladares, Carmen Cañavate, Jose María Requena, Manuel Carlos López, Jorge Alvar, Javier Moreno
Zoonotic visceral leishmaniasis (ZVL) is a parasitic disease caused by Leishmania infantum/L. chagasi that is emerging as an important medical and veterinary problem. Dogs are the domestic reservoir for this parasite and, therefore, the main target for controlling the transmission to humans. In the present work, we have evaluated the immunogenicity of the Leishmania infantum heat shock protein (HSP)-70, paraflagellar rod protein (PFR)-2 and kinetoplastida membrane protein (KMP)-11 recombinant proteins in dogs experimentally infected with the parasite...
March 28, 2008: Vaccine
https://www.readbyqxmd.com/read/18185158/diagnostic-and-therapeutic-challenges
#17
Diego Sanchez-Chicharro, Jose C Pastor, Maria I Lopez Galvez, Rosa M Coco Martin, Ruben Cuadrado Asensio, Mark Spirn, Peter S Kaiser, Arthur D Fu
No abstract text is available yet for this article.
January 2008: Retina
https://www.readbyqxmd.com/read/17691416/-coping-self-efficacy-against-alcohol-and-other-drugs-use-as-treatment-outcome-predictor-and-its-relation-with-personality-dimensions-evaluation-of-a-sample-of-addicts-using-dtcq-vip-and-mcm-ii
#18
Juan Chicharro Romero, Eduardo J Pedrero Pérez, María Pérez López
Perceived self-efficacy in being able to resist taking drugs when faced with situations of stress or social pressure was studied using the Drug Taking Confidence Questionnaire (DTCQ; Annis and Martin, 1985). In general, stronger self-efficacy is associated with the achievement of therapeutic objectives. We studied the predictive capacity of this questionnaire, administered at the beginning of treatment to a sample of substance-addicts in respect of compliance with objectives. We made a psychometric study of the instrument and its relationship with personality variables assessed with MCMI-II and VIP Data suggest that: (1) 50 DTCQ items can be reduced to 8 and even to 3 in order to achieve the same results, (2) self-efficacy at the beginning of treatment only predicts outcomes in the short-term, and (3) self-efficacy is a characteristic that is explained on the basis of personality structure...
2007: Adicciones
https://www.readbyqxmd.com/read/17534784/effects-of-inspiratory-muscle-training-on-exercise-capacity-and-spontaneous-physical-activity-in-elderly-subjects-a-randomized-controlled-pilot-trial
#19
RANDOMIZED CONTROLLED TRIAL
S Aznar-Lain, A L Webster, S Cañete, A F San Juan, L M López Mojares, M Pérez, A Lucia, J L Chicharro
Inspiratory muscle training (IMT) has been shown to improve exercise capacity in diseased populations. We chose to examine the effects of eight weeks of IMT on exercise capacity and spontaneous physical activity in elderly individuals. Eighteen moderately active elderly subjects (68.1 +/- 6.8 years [mean +/- SD]; range 58 - 78 years) were randomly assigned to either an experimental group (n = 9) or a control group (n = 9) in a double-blind manner. All subjects underwent inspiratory muscle testing, treadmill exercise testing and a four-day measurement period of spontaneous physical activity (using accelerometry) both pre- and post-intervention...
December 2007: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/11579061/effects-of-an-endurance-cycling-competition-on-resting-serum-insulin-like-growth-factor-i-igf-i-and-its-binding-proteins-igfbp-1-and-igfbp-3
#20
J L Chicharro, A López-Calderon, J Hoyos, A I Martín-Velasco, G Villa, M A Villanúa, A Lucía
OBJECTIVES: To determine whether consecutive bouts of intense endurance exercise over a three week period alters serum concentrations of insulin-like growth factor I (IGF-I) and/or its binding proteins. METHODS: Seventeen professional cyclists (mean (SEM) VO(2)MAX, 74.7 (2.1) ml/kg/min; age, 27 (1) years) competing in a three week tour race were selected as subjects. Blood samples were collected at each of the following time points: t(0) (control, before the start of competition), t(1) (end of first week), and t(3) (end of third week)...
October 2001: British Journal of Sports Medicine
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