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JOURNAL ARTICLE
Celia Boukadida, Blanca Taboada, Marina Escalera-Zamudio, Pavel Isa, José Ernesto Ramírez-González, Joel Armando Vazquez-Perez, José Esteban Muñoz-Medina, Concepción Grajales-Muñiz, Carolina González-Torres, Francisco Javier Gaytán-Cervantes, Alma Rincón-Rubio, Margarita Matías-Florentino, Héctor Esteban Paz-Juárez, Alejandro Sanchez-Flores, Edgar Mendieta-Condado, Gisela Barrera-Badillo, Lucía Hernández-Rivas, Susana López, Irma López-Martínez, Santiago Ávila-Ríos, Carlos F Arias
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has shown a wide spectrum of clinical manifestations ranging from asymptomatic infections to severe disease and death. Pre-existing medical conditions and age have been mainly linked to the development of severe disease; however, the potential association of viral genetic characteristics with different clinical conditions remains unclear. SARS-CoV-2 variants with increased transmissibility were detected early in the pandemics, and several variants with potential relevance for public health are currently circulating around the world...
February 23, 2022: Microbiology Spectrum
#22
JOURNAL ARTICLE
Ana E Gutiérrez-Cabrera, Raúl Badillo Montaño, Lorena González, Sandra M Ospina-Garcés, Alex Córdoba-Aguilar
Even when an animal has a generalist diet, different food sources can impact its body shape and fluctuating asymmetry (a stress indicator; FA). To test this, we varied the food source (mammalian, avian or defibrinated mammalian blood; and control animals - ad libitum feeding) and the time of feeding (every 8 days, 45 days and ad libitum) having the Chagas triatomine vector, Triatoma pallidipennis (Stål, 1892), as a study animal which has presumable generalist feeding habits. This factorial design was applied since first instar animals until adulthood...
March 2022: Infection, Genetics and Evolution
#23
JOURNAL ARTICLE
Blanca Taboada, Selene Zárate, Pavel Iša, Celia Boukadida, Joel Armando Vazquez-Perez, José Esteban Muñoz-Medina, José Ernesto Ramírez-González, Andreu Comas-García, Concepción Grajales-Muñiz, Alma Rincón-Rubio, Margarita Matías-Florentino, Alejandro Sanchez-Flores, Edgar Mendieta-Condado, Jerome Verleyen, Gisela Barrera-Badillo, Lucía Hernández-Rivas, Fidencio Mejía-Nepomuceno, José Arturo Martínez-Orozco, Eduardo Becerril-Vargas, Susana López, Irma López-Martínez, Santiago Ávila-Ríos, Carlos F Arias
During the first year of the SARS-CoV-2 pandemic in Mexico, more than two million people were infected. In this study, we analyzed full genome sequences from 27 February 2020 to 28 February 2021 to characterize the geographical and temporal distribution of SARS-CoV-2 lineages and identify the most common circulating lineages during this period. We defined six different geographical regions with particular dynamics of lineage circulation. The Northeast and Northwest regions were the ones that exhibited the highest lineage diversity, while the Central south and South/Southeast regions presented less diversity with predominance of a certain lineage...
October 26, 2021: Viruses
#24
Esperanza M Garcia-Oropesa, Yoscelina E Martinez-Lopez, Sonia María Ruiz-Cejudo, José Darío Martínez-Ezquerro, Alvaro Diaz-Badillo, Carlos Ramirez-Pfeiffer, Alejandra Bustamante-Fuentes, Elena B Lopez-Sosa, Oscar O Moctezuma-Chavez, Edna J Nava-Gonzalez, Adriana L Perales-Torres, Lucia M Perez-Navarro, Marisol Rosas-Diaz, Kathleen Carter, Beatriz Tapia, Juan C Lopez-Alvarenga
Mexicans and Mexican Americans share culture, genetic background, and predisposition for chronic complications associated with obesity and diabetes making imperative efficacious treatments and prevention. Obesity has been treated for centuries focused-on weight loss while other treatments on associated conditions like gout, diabetes (T2D), and hypertriglyceridemia. To date, there is no systematic review that synthesizes the origin of obesity clinics in Mexico and the efforts to investigate treatments for obesity tested by randomized clinical trials (RCT)...
2021: Frontiers in Medicine
#25
JOURNAL ARTICLE
Preetesh Jain, Shuangtao Zhao, Hun Ju Lee, Holly A Hill, Chi Young Ok, Rashmi Kanagal-Shamanna, Fredrick B Hagemeister, Nathan Fowler, Luis Fayad, Yixin Yao, Yang Liu, Omar B Moghrabi, Lucy Navsaria, Lei Feng, Graciela M Nogueras Gonzalez, Guofan Xu, Selvi Thirumurthi, David Santos, Cezar Iliescu, Guilin Tang, L Jeffrey Medeiros, Francisco Vega, Michelle Avellaneda, Maria Badillo, Christopher R Flowers, Linghua Wang, Michael L Wang
PURPOSE: Most patients with mantle cell lymphoma (MCL) are older. In this study, we investigated the efficacy and safety of a chemotherapy-free combination with ibrutinib and rituximab (IR) in previously untreated older patients with MCL (age ≥ 65 years). METHODS: We enrolled 50 patients with MCL in this single-institution, single-arm, phase II clinical trial (NCT01880567). Patients with Ki-67% ≥ 50% and blastoid morphology were excluded. Ibrutinib was administered with rituximab up to 2 years with continuation of ibrutinib alone...
January 10, 2022: Journal of Clinical Oncology
#26
JOURNAL ARTICLE
Oscar de Jesús Calva-Cruz, Nallely S Badillo-Larios, Antonio De León-Rodríguez, Eduardo Espitia-Rangel, Raúl González-García, Edgar Alejandro Turrubiartes-Martinez, Arnulfo Castro-Gallardo, Ana Paulina Barba de la Rosa
OBJECTIVE: The aim of this work was to characterize Lippia graveolens oleoresins, obtained by Supercritical Fluid Extraction (SFE), from crops collected at different locations in Mexico. The antimicrobial effect of oleoresins was tested in reference strains and clinical isolates of susceptible and multidrug-resistant (MDR) strains of Enterococcus faecalis and Staphylococcus aureus . SIGNIFICANCE: The increasing of MDR strains is becoming a global public health problem that has led to the search for new treatments, and essential oils have resurged as a source of compounds with bactericidal functions...
February 20, 2022: Drug Development and Industrial Pharmacy
#27
JOURNAL ARTICLE
Eva López-Rivera, Juan José González-Badillo, Vanesa España-Romero
BACKGROUND: The ability to generate high levels of force with the finger flexor muscles and sustain it for the maximum time was reported as a climbing performance factor. This study aimed to answer the question of which is the most reliable edge depth to measure maximum hanging time in non-elite and elite rock climbers: 6, 8, 10, 12 or 14 mm. METHODS: Thirty-six climbers (10 female, 26 male; 6b-8c redpoint level) were assessed twice, one week apart. RESULTS: Systematic bias (95 % limits of agreements) was -1...
January 2022: Gait & Posture
#28
JOURNAL ARTICLE
Hector S Alvarez-Manzo, Rafael Badillo-Davila, Alejandro Olaya-Gomez, Barbara Gonzalez-de-Cossio-Tello, Rafael Cardoso-Arias, Emilio S Gamboa-Balzaretti, Carlos D Baranzini-Rogel, Gabriel Garcia-Garnica, Luis E Hernandez-Corrales, Carlos A Linares-Koloffon
The COVID-19 pandemic forced the scientific community and the pharmaceutical industry to develop new vaccines, in an attempt to reach herd immunity and stop the SARS-CoV-2 from spreading. However, to ensure vaccination among the general population, COVID-19 vaccine intention must be measured. So far, no studies have focused on rural residents in Latin America, which represent approximately 20% of the population of this geographical region. In this study, we present the validation of a self-developed questionnaire, which was validated in a pilot study with 40 Spanish-speaking Mexican rural residents in the state of Guerrero, Mexico...
August 26, 2021: Vaccines
#29
REVIEW
José J Valdés-Aguayo, Idalia Garza-Veloz, José I Badillo-Almaráz, Sofia Bernal-Silva, Maria C Martínez-Vázquez, Vladimir Juárez-Alcalá, José R Vargas-Rodríguez, María L Gaeta-Velasco, Carolina González-Fuentes, Lorena Ávila-Carrasco, Margarita L Martinez-Fierro
Background and Objectives . The importance of mitochondria in inflammatory pathologies, besides providing energy, is associated with the release of mitochondrial damage products, such as mitochondrial DNA (mt-DNA), which may perpetuate inflammation. In this review, we aimed to show the importance of mitochondria, as organelles that produce energy and intervene in multiple pathologies, focusing mainly in COVID-19 and using multiple molecular mechanisms that allow for the replication and maintenance of the viral genome, leading to the exacerbation and spread of the inflammatory response...
September 3, 2021: Medicina
#30
JOURNAL ARTICLE
Angela Mariela González-Montemayor, José Fernando Solanilla-Duque, Adriana C Flores-Gallegos, Claudia Magdalena López-Badillo, Juan Alberto Ascacio-Valdés, Raúl Rodríguez-Herrera
In this study, proximal composition, mineral analysis, polyphenolic compounds identification, and antioxidant and functional activities were determined in green bean (GBF), mesquite (MF), and pea (PF) flours. Different mixtures of legume flour and wheat flour for bread elaboration were determined by a simplex-centroid design. After that, the proximal composition, color, specific volume, polyphenol content, antioxidant activities, and functional properties of the different breads were evaluated. While GBF and PF have a higher protein content (41-47%), MF has a significant fiber content (19...
September 20, 2021: Foods (Basel, Switzerland)
#31
JOURNAL ARTICLE
Txomin Pérez-Bilbao, David García-González, Álvaro Martos-Bermúdez, Sandra Nieto, Teresa Del Campo, Margarita Pérez-Ruiz, Alejandro F San Juan
BACKGROUND: The "effort character" (EC) is a resistance training method without reaching muscle failure. It was defined by González-Badillo and Gorostiaga Ayestarán (2002) as the relationship between the repetitions performed and the repetitions achievable. Then, the EC is at its maximum (i.e., 100%) when the subject realizes all the repetitions possible in a series with any load. Therefore, an EC of 50% indicates execution of 50% of the repetitions achievable in a series. This study aimed to determine the effects of two programs of eight weeks of concurrent training (CT) with different EC over muscle strength (MS), cardiorespiratory fitness (CRF), functional mobility (FM), health-related quality of life (HRQoL), and lipid profile (LP) among hospital workers...
September 3, 2021: International Journal of Environmental Research and Public Health
#32
JOURNAL ARTICLE
Abril Paulina Rodríguez-Maldonado, Joel Armando Vázquez-Pérez, Alberto Cedro-Tanda, Blanca Taboada, Celia Boukadida, Claudia Wong-Arámbula, Tatiana Ernestina Nuñez-García, Natividad Cruz-Ortiz, Gisela Barrera-Badillo, Lucía Hernández-Rivas, Irma López-Martínez, Alfredo Mendoza-Vargas, Juan Pablo Reyes-Grajeda, Nicolas Alcaraz, Fernando Peñaloza-Figueroa, Dulibeth Gonzalez-Barrera, Daniel Rangel-DeLeon, Luis Alonso Herrera-Montalvo, Fidencio Mejía-Nepomuceno, Alejandra Hernández-Terán, Mario Mújica-Sánchez, Eduardo Becerril-Vargas, José Arturo Martínez-Orozco, Rogelio Pérez-Padilla, Jorge Salas-Hernández, Alejandro Sanchez-Flores, Pavel Isa, Margarita Matías-Florentino, Santiago Ávila-Ríos, José Esteban Muñoz-Medina, Concepción Grajales-Muñiz, Angel Gustavo Salas-Lais, Andrea Santos Coy-Arechavaleta, Alfredo Hidalgo-Miranda, Carlos F Arias, José Ernesto Ramírez-González
SARS-CoV-2 variants emerged in late 2020, and at least three variants of concern (B.1.1.7, B.1.351, and P1) have been reported by WHO. These variants have several substitutions in the spike protein that affect receptor binding; they exhibit increased transmissibility and may be associated with reduced vaccine effectiveness. In the present work, we report the identification of a potential variant of interest, harboring the mutations T478K, P681H, and T732A in the spike protein, within the newly named lineage B...
August 27, 2021: Archives of Virology
#33
JOURNAL ARTICLE
Ronald M Sánchez-Ávila, Edmar Uribe-Badillo, Carlos Fernández-Vega González, Francisco Muruzabal, Borja de la Sen-Corcuera, Begoña Baamonde, Luis M Quirós, Eduardo Anitua, Jesús Merayo-Lloves
This study aimed to investigate the use of Plasma Rich in Growth Factors (PRGF) associated with tissue ReGeneraTing Agent (RGTA) drops for the treatment of noninfectious corneal ulcers. RGTA treatment was applied (one drop every two days); however, if ulcer closure was not achieved, PRGF eye drops treatment was added (four times/day). The time taken to reach the ulcer closure, the Best Corrected Visual Acuity (BCVA), intraocular pressure (IOP), Visual Analog Scale (VAS, in terms of frequency and severity of symptoms), and Ocular Surface Disease Index (OSDI) were evaluated...
July 2, 2021: Vision
#34
JOURNAL ARTICLE
José Daniel García-García, Julia Cecilia Anguiano-Cabello, Roberto Arredondo-Valdés, Claudio Alexis Candido Del Toro, José Luis Martínez-Hernández, Elda Patricia Segura-Ceniceros, Mayela Govea-Salas, Mónica Lizeth González-Chávez, Rodolfo Ramos-González, Sandra Cecilia Esparza-González, Juan Alberto Ascacio-Valdés, Claudia Magdalena López-Badillo, Anna Ilyina
In Mexico, mistletoes have several applications in traditional medicine due to the great variety of compounds with biological activities that have not been characterized to date. The goals of the present study are to analyze the composition of minerals and phytochemical compounds in Mexican mistletoes Phoradendron bollanum and Viscum album subs. austriacum qualitatively and quantitatively, identify the compounds using HPLC-MS, and assess the antimicrobial potential in phytopathogenic microorganism control. Mineral content was evaluated with X-ray fluorescence...
June 26, 2021: Plants (Basel, Switzerland)
#35
JOURNAL ARTICLE
Miguel Sánchez-Moreno, David Rodríguez-Rosell, David Díaz-Cueli, Fernando Pareja-Blanco, Juan José González-Badillo
PURPOSE: This study analyzed the effects of 3 training interventions: 1 isolated endurance training (ET) and 2 concurrent training (CT), which differed in the velocity loss (VL) magnitude allowed during the resistance training (RT) set: 15% (VL15) versus 45%, on strength and endurance running performance. METHODS: A total of 33 resistance- and endurance-trained men were randomly allocated into 3 groups: VL15, VL 45%, and ET. ET was similar across all groups. The CT groups differed in the VL allowed during the RT set...
June 1, 2021: International Journal of Sports Physiology and Performance
#36
RANDOMIZED CONTROLLED TRIAL
David Rodríguez-Rosell, Juan Manuel Yáñez-García, Ricardo Mora-Custodio, Luis Sánchez-Medina, Juan Ribas-Serna, Juan José González-Badillo
This study aimed to compare the effects of three resistance training (RT) programs differing in the magnitude of velocity loss (VL) allowed in each exercise set: 10%, 30%, or 45% on changes in strength, vertical jump, sprint performance, and EMG variables. Thirty-three young men were randomly assigned into three experimental groups (VL10%, VL30%, and VL45%; n = 11 each) that performed a velocity-based RT program for 8 weeks using only the full squat exercise (SQ). Training load (55-70% 1RM), frequency (2 sessions/week), number of sets (3), and inter-set recovery (4 min) were identical for all groups...
August 2021: Scandinavian Journal of Medicine & Science in Sports
#37
JOURNAL ARTICLE
Pedro Jiménez-Reyes, Adrian Castaño-Zambudio, Víctor Cuadrado-Peñafiel, Jorge M González-Hernández, Fernando Capelo-Ramírez, Luis M Martínez-Aranda, Juan J González-Badillo
Strength and conditioning specialists commonly deal with the quantification and selection the setting of protocols regarding resistance training intensities. Although the one repetition maximum (1RM) method has been widely used to prescribe exercise intensity, the velocity-based training (VBT) method may enable a more optimal tool for better monitoring and planning of resistance training (RT) programs. The aim of this study was to compare the effects of two RT programs only differing in the training load prescription strategy (adjusting or not daily via VBT) with loads from 50 to 80% 1RM on 1RM, countermovement (CMJ) and sprint...
2021: PeerJ
#38
JOURNAL ARTICLE
Luis A Marco-Contreras, Beatriz Bachero-Mena, David Rodríguez-Rosell, Juan J González-Badillo
PURPOSE: To analyze the relationships between the evolution of training-load values and countermovement jump (CMJ) as an indicator of stress and fatigue in a high-level 800-m runner during a whole season, including indoor (ID) and outdoor season (OD). METHODS: Over 42 weeks, daily training load was quantified as the result of the product of the intensity and volume, and it was termed load index (LI). CMJ was measured in every running session after warm-up and immediately after the last effort of the session...
February 24, 2021: International Journal of Sports Physiology and Performance
#39
JOURNAL ARTICLE
María de Lourdes Jiménez-Badillo, César Meiners-Mandujano, Gabriela Galindo-Cortes, Piedad S Morillo-Velarde, Roberto González-Gómez, Irene de Los Angeles Barriga-Sosa, Ricardo Pliego-Cárdenas
Knowledge on species taxonomic identity is essential to understand biological and biogeographical processes and for studies on biodiversity. Species the genus Tremoctopus have been confused in the past and are inconsistently identified. To clarify of the taxonomic diagnosis Tremoctopus violaceus Delle Chiaje, 1830, an evaluation of morphological and meristic characters, as well as morphometric indices and genetic analyses, was undertaken. The analyzed octopod was an opportunistically collected mature female of 640 mm in total length, with a mantle length of 135 mm and a total weight of 1...
2021: ZooKeys
#40
JOURNAL ARTICLE
Pablo Nájera-Ferrer, Carlos Pérez-Caballero, Juan José González-Badillo, Fernando Pareja-Blanco
PURPOSE: This study aimed to analyze the response to 4 concurrent training interventions differing in the training sequence and in the velocity loss (VL) threshold during strength training (20% vs 40%) on following endurance and strength performance. METHODS: A randomized crossover research design was used. Sixteen trained men performed 4 training interventions consisting of endurance training (ET) followed by resistance training (RT), with 20% and 40% VL, respectively (ET + RT20 and ET + RT40), and RT with 20% and 40% VL, respectively, followed by ET (RT20 + ET and RT40 + ET)...
February 4, 2021: International Journal of Sports Physiology and Performance
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