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https://www.readbyqxmd.com/read/29053431/survey-of-gross-and-histopathologic-findings-in-two-wintering-subpopulations-of-sandhill-cranes-antigone-canadensis
#1
Martha Hensel, Miranda Bertram, Raquel Rech, Gabriel L Hamer, Sarah A Hamer
Sandhill Cranes (Antigone canadensis) of the midcontinent population (MCP) and Rocky Mountain population (RMP) are migratory game birds with stable populations that travel between Canada and the southern USA and Mexico. In the winters of 2012-14, we performed gross and histologic examinations of 43 hunter-harvested Sandhill Cranes in Texas (MCP) and New Mexico (RMP) to assess the impact of disease on populations. Lesions were significantly more common in the MCP relative to the RMP, likely reflecting differential environmental exposure to pathogens and parasites...
October 20, 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/29051791/hyalinizing-trabecular-tumor-of-the-thyroid-gland-and-its-significant-diagnostic-issue
#2
Dustin J Jones, Christopher R Kieliszak, Sanjay S Patel, Christopher R Selinsky
BACKGROUND: Hyalinizing trabecular tumors (HTT) are rare follicular cell-derived tumors of the thyroid gland that are infrequently reported in otolaryngology literature. We present here an interesting case of HTT which provides the basis for review of this entity's clinical characteristics, criteria useful in making the diagnosis, and any currently available therapeutic modalities. CASE PRESENTATION: A 70-year-old Caucasian female underwent a CT scan of her chest and was incidentally found to have a nodule within the right thyroid lobe...
2017: Thyroid Research
https://www.readbyqxmd.com/read/29050816/applicability-of-handmade-expanded-polytetrafluoroethylene-trileaflet-valved-conduits-for-pulmonary-valve-reconstruction-an-ex%C3%A2-vivo-and-in%C3%A2-vivo-study
#3
Chung-Dann Kan, Jieh-Neng Wang, Wei-Ling Chen, Pong-Jeu Lu, Ming-Yao Chan, Chia-Hung Lin, Wan-Chin Hsieh
OBJECTIVE: The handmade expanded polytetrafluoroethylene (ePTFE) trileaflet-valved conduit could potentially be used as a substitute pulmonary valve replacement material, especially in children. The current study investigated (1) the function of the ePTFE trileaflet-valved conduits in an ex vivo experimental system and (2) the short-term performance of the conduit in a porcine model to verify its clinical applicability. METHODS: The competency of the ePTFE trileaflet-valved conduits was estimated through ex vivo (using a pulmonary mock circulation loop) and in vivo (in a porcine model with a damaged pulmonary valve) experiments...
September 20, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29049945/the-ages-and-stages-questionnaire-latent-factor-structure-and-growth-of-latent-mean-scores-over-time
#4
Oscar L Olvera Astivia, Barry Forer, Gwenden L Dueker, Candace Cowling, Martin Guhn
BACKGROUND: Very little research exists that looks at the Ages and Stages Questionnaire simultaneously from a modern latent variable point of view and by looking at its psychometric properties over time. AIMS: To explore the latent factor structure of the ASQ using Exploratory Structural Equation Modeling techniques for ordinal data and investigate its change over time using the method of vertical scaling from multidimensional Item Response Theory. STUDY DESIGN: Longitudinal, with the same children being assessed at multiple timepoints...
October 16, 2017: Early Human Development
https://www.readbyqxmd.com/read/29048256/skiping-with-head-start-teachers-influence-of-t-skip-on-object-control-skills
#5
Ali Brian, Jacqueline D Goodway, Jessica A Logan, Sue Sutherland
PURPOSE: Children from disadvantaged settings are at risk for delays in their object-control (OC) skills. Fundamental motor skill interventions, such as the Successful Kinesthetic Instruction for Preschoolers (SKIP) Program, are highly successful when led by motor development experts. However, few preschools employ such experts. This study examined the extent to which Head Start teachers delivering an 8-week teacher-led SKIP (T-SKIP) intervention elicited learning of OC skills for Head Start children...
October 19, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/29045967/-early-surgical-treatment-of-multi-segmet-intramedullary-cervical-spinal-cord-ependymoma
#6
C C Ma, G Z Lin, Z Y Wang
OBJECTIVE: To investigate the early clinical treatment and prognosis of multi-segment intramedullary cervical ependymoma. METHODS: Twenty patients with multi-segment (more than 3 segments) intramedullary spinal ependymoma (McCormic grade I) were microsurgically treated with assistance of intraoperative neuroelectrophysiological monitoring. None of them received postoperative radiotherapy. Preoperatively all the patients underwent MRI examination and their neurologically function was assessed by McCormic classification method...
October 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29045324/a-ball-skills-intervention-in-preschoolers-the-champ-randomized-controlled-trial
#7
Leah E Robinson, Sanne L C Veldman, Kara K Palmer, Anthony D Okely
PURPOSE: Fundamental motor skills (FMS) contribute to positive health trajectories. A high level of competence in ball skills (a subset of FMS) is a predictor for time spent in moderate- to vigorous-intensity physical activity during adolescence. This study examined the effects of a ball skills intervention on ball skill competence among preschool-aged boys and girls. METHODS: This is a two-armed randomized controlled trial. A total of 124 preschoolers (Mage ± SD = 48...
November 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29043783/marine-mammal-microbiota-yields-novel-antibiotic-with-potent-activity-against-clostridium-difficile
#8
Jessica L Ochoa, Laura M Sanchez, Byoung-Mo Koo, Jennifer S Doherty, Manohary Rajendram, Kerwyn Casey Huang, Carol A Gross, Roger G Linington
The recent explosion of research on the microbiota has highlighted the important interplay between commensal microorganisms and the health of their cognate hosts. Metabolites isolated from commensal bacteria have been demonstrated to possess a range of antimicrobial activities, and it is widely believed that some of these metabolites modulate host behavior, affecting predisposition to disease and pathogen invasion. Our access to the local marine mammal stranding network and previous successes in mining the fish microbiota poised us to test the hypothesis that the marine mammal microbiota is a novel source of commensal bacteria-produced bioactive metabolites...
October 18, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/29037743/the-effect-of-platelet-rich-fibrin-on-autologous-osteochondral-transplantation-an-in-vivo-porcine-model
#9
S Y Sheu, C H Wang, Y H Pao, Y T Fu, C H Liu, C H Yao, T F Kuo
BACKGROUND: This work aimed to evaluate the efficacy of cartilage transplantation to the medial femoral condyle±platelet-rich fibrin (PRF) augmentation in a porcine model. The hypothesis of the study was that PRF may act as a bioactive cell scaffold to fill defects and enhance cartilage regeneration. METHODS: Thirty-two knees of 16 miniature pigs were randomly assigned to four groups. The critical-size osteochondral defects (8x5mm) in femoral condyle of both knees were treated with one of the following: group 1-untreated controls; group 2-cartilage fragments alone; group 3-PRF alone; group 4-PRFT+cartilage fragments...
October 13, 2017: Knee
https://www.readbyqxmd.com/read/29036466/insights-into-epigenome-evolution-from-animal-and-plant-methylomes
#10
Soojin V Yi
Evolutionary studies of DNA methylation begin to provide insights into the underlying forces governing the variation of genomic DNA methylation across different species. Comparisons of gross levels of DNA methylation between distantly related species indicate that the size of the genome and the level of genomic DNA methylation are positively correlated. In plant genomes, this can be reliably explained by the contents of repetitive sequences, while the underlying driver of this correlation is less clear in animal genomes...
September 25, 2017: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29035576/inter-and-intrarater-reliabilities-of-the-test-of-gross-motor-development-third-edition-among-experienced-tgmd-2-raters
#11
Hyokju Maeng, E Kipling Webster, E Andrew Pitchford, Dale A Ulrich
The purpose of this study was to examine the inter- and intrarater reliabilities of the Test of Gross Motor Development-third edition (TGMD-3). The TGMD-3 was administered to 10 typically developing children. Five raters with experience using the Test of Gross Motor Development-second edition (TGMD-2) scored the digitally recorded performances and then rescored the same performances after a period of 2 weeks. Intraclass correlation (ICC) was used to examine both inter- and intrarater reliabilities of scores...
October 16, 2017: Adapted Physical Activity Quarterly: APAQ
https://www.readbyqxmd.com/read/29034266/bladder-pain-in-an-ll-37-interstitial-cystitis-and-painful-bladder-syndrome-model
#12
Wanjian Jia, Austin J Schults, Mark Martin Jensen, Xiangyang Ye, Jeremiah A Alt, Glenn D Prestwich, Siam Oottamasathien
Our goal was to evaluate the pain response in an LL-37 induced murine model for interstitial cystitis/painful bladder syndrome (IC/PBS). In particular, we sought to characterize the dose dependence, time-course, and relationship of LL-37 induced bladder inflammation and pain. The IC/PBS model was induced in C57Bl/6 mice by instilling 50 μL of LL-37, an immunomodulatory human cathelicidin (anti-microbial peptide), in the bladder for 1 hr. Pain responses were measured using von Frey filaments (0.04 gm to 4.0 gm) before and after LL-37 instillation...
2017: American Journal of Clinical and Experimental Urology
https://www.readbyqxmd.com/read/29033770/acinar-cell-cystadenocarcinoma-of-the-pancreas
#13
Keita Aoto, Tatsuo Shimura, Yasuhide Kofunato, Ryo Okada, Rei Yashima, Yuichiro Kiko, Seiichi Takenoshita
Acinar cell cystadenocarcinoma is a rare malignant epithelial neoplasm of the pancreas with a diffusely cystic, gross architecture in which the cysts are lined with neoplastic epithelial cells that demonstrate evidence of pancreatic exocrine enzyme production. This is the 10th case that has been reported in the literature. A 77-year-old male complaining of left hypochondrial pain was referred to our hospital for treatment of a pancreatic tumor. A huge, honeycomb-structured tumor was detected in the pancreatic tail...
May 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29033382/clinical-pathological-correlations-in-three-patients-with-fibrodysplasia-ossificans-progressiva
#14
Kelly L Wentworth, Katherine Bigay, Tea V Chan, Jennifer P Ho, Blanca M Morales, Joseph Connor, Erin Brooks, M Shahriar Salamat, Henry Charles Sanchez, Geoffrey Wool, Robert J Pignolo, Frederick S Kaplan, Edward C Hsiao
OBJECTIVE: Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare genetic disorder in which heterotopic bone forms in the soft tissues. This often occurs in response to injury or inflammation, leading to joint immobilization and significant disability. There are currently no definitive treatment options for this devastating disease. Although the most dramatic phenotype in FOP is the episodic and progressive heterotopic ossification, patients report a number of symptoms that affect other organ systems...
October 12, 2017: Bone
https://www.readbyqxmd.com/read/29032244/the-impact-of-sparc-on-age-related-cardiac-dysfunction-and-fibrosis-in-drosophila
#15
Leigh Vaughan, Richard Marley, Sara Miellet, Paul S Hartley
Tissue fibrosis, an accumulation of extracellular matrix proteins such as collagen, accompanies cardiac ageing in humans and this is linked to an increased risk of cardiac failure. The mechanisms driving age-related tissue fibrosis and cardiac dysfunction are unclear, yet clinically important. Drosophila is amenable to the study of cardiac ageing as well as collagen deposition; however it is unclear whether collagen accumulates in the ageing Drosophila heart. This work examined collagen deposition and cardiac function in ageing Drosophila, in the context of reduced expression of collagen-interacting protein SPARC (Secreted Protein Acidic and Rich in Cysteine) an evolutionarily conserved protein linked with fibrosis...
October 12, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/29032167/evaluation-of-embryotoxic-and-teratogenic-effects-of-the-oil-extracted-from-caryocar-brasiliense-cambess-pulp-in-rats
#16
Giseli Karenina Traesel, Fernando Freitas de Lima, Ariany Carvalho Dos Santos, Roosevelt Isaias Carvalho Souza, Daniela Torres Cantadori, Carlos Roberto Kretschmer, Vinicius João Navarini, Silvia Aparecida Oesterreich
The objective of this study was to evaluate the maternal, embryotoxic and teratogenic effects of Caryocar brasiliense pulp oil (OPCB), oil widely used in Brazilian cuisine and traditional medicine. Pregnant Wistar female rats were used in this study for three treatment groups (250, 500 and 1000 mg/kg/day) and a control group. The OPCB was administered orally throughout the period of organogenesis of females (6th until the 15th day of gestation). The pregnant females were gross necropsied on d20, followed by maternal and fetus examination, to evaluate the teratogenicity, reproductive and developmental performance of OPCB...
October 12, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29031330/histological-changes-in-the-proximal-suspensory-ligament-after-neurectomy-of-the-deep-branch-of-the-lateral-palmar-nerve-of-horses-with-induced-proximal-suspensory-desmitis
#17
Gabriela Lopez-Navarro, Francisco J Trigo-Tavera, Alejandro Rodriguez-Monterde, Gabriel Gutierrez-Ospina, Miguel Arechavaleta-Velasco, John Schumacher, James Schumacher
Proximal suspensory desmitis (PSD) is a common cause of lameness in the pelvic limb, but could also affect the thoracic limb of competing and non-competing horses. Most horses diagnosed with PSD in a thoracic limb respond to rest followed by controlled exercise, but in a small percentage of affected horses, lameness persists. In one study, four horses chronically lame because of PSD in a thoracic limb became sound after neurectomy of the deep branch of the lateral palmar nerve (DBLPaN), which innervates the proximal aspect of the suspensory ligament (SL; Guasco et al...
September 2017: Veterinary Journal
https://www.readbyqxmd.com/read/29027325/ecological-plant-epigenetics-evidence-from-model-and-non-model-species-and-the-way-forward
#18
Christina L Richards, Conchita Alonso, Claude Becker, Oliver Bossdorf, Etienne Bucher, Maria Colomé-Tatché, Walter Durka, Jan Engelhardt, Bence Gaspar, Andreas Gogol-Döring, Ivo Grosse, Thomas P van Gurp, Katrin Heer, Ilkka Kronholm, Christian Lampei, Vít Latzel, Marie Mirouze, Lars Opgenoorth, Ovidiu Paun, Sonja J Prohaska, Stefan A Rensing, Peter F Stadler, Emiliano Trucchi, Kristian Ullrich, Koen J F Verhoeven
Growing evidence shows that epigenetic mechanisms contribute to complex traits, with implications across many fields of biology. In plant ecology, recent studies have attempted to merge ecological experiments with epigenetic analyses to elucidate the contribution of epigenetics to plant phenotypes, stress responses, adaptation to habitat, and range distributions. While there has been some progress in revealing the role of epigenetics in ecological processes, studies with non-model species have so far been limited to describing broad patterns based on anonymous markers of DNA methylation...
October 12, 2017: Ecology Letters
https://www.readbyqxmd.com/read/29027183/actinic-cystitis-causes-treatment-and-experience-of-a-single-centre-in-the-last-five-years
#19
Mario S Mangano, Alberto De Gobbi, Matteo Ciaccia, Claudio Lamon, Francesco Beniamin, Luigino Maccatrozzo
INTRODUCTION: Actinic cystitis (AC) is the manifestation of symptoms and signs following pelvic radiotherapy.Pelvic radiotherapy produces both acute and chronic damage and such damage may have a devastating impact on the quality and on the amount of life of the patient. OBJECTIVES: To evaluate the number of radical cystectomies that have become necessary in the last five years in our department for AC after radiation treatment. MATERIALS AND METHODS: From February 2012 to February 2017, 11 patients underwent "open" cystectomy for AC...
October 11, 2017: Urologia
https://www.readbyqxmd.com/read/29027138/recurrence-of-optimally-treated-malignant-peritoneal-mesothelioma-with-cytoreduction-and-heated-intraperitoneal-chemotherapy
#20
Danielle R Heller, Cody Chiuzan, Robert N Taub, Joshua C Leinwand, Allison M Greene, Gleneara E Bates, John A Chabot, Michael D Kluger
BACKGROUND: The prognosis for patients with diffuse malignant peritoneal mesothelioma has dramatically improved with cytoreductive surgery and intraperitoneal chemotherapy. Little is known about disease recurrence after treatment. We analyzed the time to and predictors of recurrence in a large cohort of optimally treated patients. METHODS: We examined 113 patients completing a two-stage cytoreduction and intraperitoneal chemotherapy protocol. All patients achieved optimal surgical resection with completeness of cytoreduction (CC) score ≤ 1 and were divided into two groups based on absence (Group A) or presence (Group B) of gross disease at the outset of the second operation...
October 12, 2017: Annals of Surgical Oncology
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