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https://www.readbyqxmd.com/read/28637143/validity-and-reliability-of-an-activity-monitor-to-quantify-arm-movements-and-activity-in-adults-following-distal-radius-fracture
#1
Andrea M Bruder, Jodie A McClelland, Nora Shields, Karen J Dodd, Raphael Hau, Alexander T M van de Water, Nicholas F Taylor
PURPOSE: To examine the validity and reliability of an activity monitor to estimate upper limb activity. METHODS: Thirty-two adults after distal radial fracture were recruited. 15 adults performed five upper limb activities during two testing sessions, one week apart to investigate criterion validity against the criterion reference of three-dimensional motion analysis, convergent validity, and test-retest reliability. 17 adults in two therapy groups wore monitors for three consecutive days at baseline and six weeks post-intervention...
February 23, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28636254/pirfenidone-reduces-subchondral-bone-loss-and-fibrosis-after-murine-knee-cartilage-injury
#2
Deva D Chan, Jun Li, Wei Luo, Dan N Predescu, Brian J Cole, Anna Plaas
Pirfenidone is an anti-inflammatory and anti-fibrotic drug that has shown efficacy in lung and kidney fibrosis. Because inflammation and fibrosis have been linked to the progression of osteoarthritis, we investigated the effects of oral Pirfenidone in a mouse model of cartilage injury, which results in chronic inflammation and joint-wide fibrosis in mice that lack hyaluronan synthase 1 (Has1(-/-) ) in comparison to wild-type. Femoral cartilage was surgically injured in wild-type and Has1(-/-) mice, and Pirfenidone was administered in food starting after 3 days...
June 21, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28635158/prepregnancy-overweight-and-obesity-are-associated-with-impaired-child-neurodevelopment
#3
Elizabeth Marie Widen, Linda Gross Kahn, Piera Cirillo, Barbara Cohn, Katrina Lynn Kezios, Pam Factor-Litvak
The authors examined the relationship of prepregnancy body mass index (BMI) and gestational weight gain (GWG) with child neurodevelopment. Mother-child dyads were a subgroup (n = 2,084) of the Child Health and Development Studies from the Oakland, California, area enrolled during pregnancy from 1959 to 1966 and followed at child age 9 years. Linear regression was used to examine associations between prepregnancy BMI, GWG, and standardized Peabody Picture Vocabulary Test and Raven Progressive Matrices scores and to evaluate effect modification of GWG by prepregnancy BMI...
June 21, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28633047/the-impacts-of-the-global-financial-crisis-on-hospitalizations-due-to-depressive-illnesses-in-taiwan-a-prospective-nationwide-population-based-study
#4
Chiachi Bonnie Lee, Chen-Mao Liao, Chih-Ming Lin
BACKGROUND: In the third quarter of 2008, a major financial crisis hit many developed countries. Taiwan suffered its own share: a rise in unemployment and a severe decline in gross domestic product. This study is to address the health consequences of this crisis on different socioeconomic populations in Taiwan. METHODS: A sample of 6,225,766 men and 5,417,651 women, was obtained and their admissions data over 2007-2012 were retrieved. Stratified into three income levels, the sample was examined on the 147,921 episodes of hospitalization due to depressive illnesses (DIs) over that period by an interrupted time series analysis for monthly incidence rates of DI hospitalizations RESULTS: The adjusted incidence rates of hospitalization (AIRH) for DIs among the low income were 10 times that of the high income group...
June 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28632137/electrospun-silk-polyaniline-conduits-for-functional-nerve-regeneration-in-rat-sciatic-nerve-injury-model
#5
Suradip Das, Manav Sharma, Dhiren Saharia, Kushal Sarma, Elizabeth Muir, Utpal Bora
The present study describes the fabrication of polyaniline-silk fibroin nanocomposite based nerve conduits and its subsequent implantation in a rat sciatic nerve injury model for peripheral nerve regeneration. This is the first in vivo study of polyaniline based nerve conduit describing the safety and efficacy of the conduits in treating peripheral nerve injuries. The nanocomposite was synthesised by electrospinning a mixture of silk fibroin protein and polyaniline wherein the silk nanofibers were observed to be uniformly coated with polyaniline nanoparticles...
June 20, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28626212/a-huge-subcutaneous-hematoma-in-an-adult-with-kasabach-merritt-syndrome
#6
Kuan-Lin Wu, Chiung-Ying Liao, Chen-Kuang Chang, Shang-Yun Ho, Yeu-Sheng Tyan, Yuan-Chun Huang
BACKGROUND Kasabach-Merritt syndrome is a potentially fatal disease that consists of hemangioma(s) with thrombocytopenia, microangiopathic hemolytic anemia, and coagulopathy. Extensive hemangiomatosis is rare. We present the radiological features and treatment strategy of a young adult suffering from Kasabach-Merritt syndrome with widespread hemangiomas and an infected huge hematoma in the right thigh. CASE REPORT A 33-year-old Taiwanese male presented with a painful 20-cm mass over his right thigh and gross hematuria for 2 days...
June 19, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28626156/a-method-to-establish-a-mouse-model-of-bone-marrow-microenvironment-injury
#7
Wenzhe Cheng, Quanhu Ge, Longfei Wan, Xiaoyi Wang, Xueling Chen, Xiangwei Wu
A normal bone marrow microenvironment plays a very important role in the normal functioning of hematopoietic stem cells. Once disturbed, this microenvironment can become favorable for the occurrence of blood disorders, cancers, and other diseases. Therefore, further studies on the bone marrow microenvironment should be performed to reveal regulatory and stem cell fate determination mechanisms and promote the development of bone marrow transplantation, tissue repair and regenerative medicine, and other fields...
June 13, 2017: Experimental Animals
https://www.readbyqxmd.com/read/28624995/how-does-it-feel-to-be-a-pathology-resident-results-of-a-survey-on-experiences-and-job-satisfaction-during-pathology-residency
#8
Burcin Pehlivanoglu, Hur Hassoy, Catarina Calle, Amelie Dendooven, ILKe Nalbantoglu, Lidiya Reshchikova, Gulen Gul, Basak Doganavsargil
Residents' career choices and professional motivation can be affected from perception of their role and recognition within a medical team as well as their educational and workplace experiences. To evaluate pathology trainees' perceptions of their pathology residency, we conducted a 42-item survey via a web-based link questioning respondents' personal and institutional background, workplace, training conditions, and job satisfaction level. For the 208 residents from different European countries who responded, personal expectations in terms of quality of life (53%) and scientific excitement (52%) were the most common reasons why they chose and enjoy pathology...
June 17, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28622885/the-impact-of-prophylactic-external-carotid-artery-ligation-on-postoperative-bleeding-after-transoral-robotic-surgery-tors-for-oropharyngeal-squamous-cell-carcinoma
#9
John Gleysteen, Scott Troob, Tyler Light, Daniel Brickman, Daniel Clayburgh, Peter Andersen, Neil Gross
BACKGROUND: Transoral robotic-assisted surgery (TORS) is increasingly utilized in the treatment of oropharyngeal squamous cell carcinoma (OPSCC). Postoperative bleeding is a significant and potentially fatal complication of TORS. Prophylactic ligation of ipsilateral external carotid artery (ECA) branches is a recognized strategy to reduce postoperative bleeding risk. We examined the incidence and sequelae of postoperative oropharyngeal bleeding with and without routine ECA ligation. METHODS: OPSCC patients treated with TORS between 2010 and 2015 with minimum 30days follow up were included...
July 2017: Oral Oncology
https://www.readbyqxmd.com/read/28622180/a-prospective-study-of-loose-tissue-fragments-in-non-small-cell-lung-cancer-resection-specimens-an-alternative-view-to-spread-through-air-spaces
#10
Hans Blaauwgeers, Douglas Flieder, Arne Warth, Alexander Harms, Kim Monkhorst, Birgit Witte, Erik Thunnissen
The World Health Organization Classification of Lung Tumors considers "Spread Through Air Spaces" a form of invasion in lung adenocarcinoma. The recently described spread of free-floating cell clusters during lung specimen sectioning, otherwise known as "Spread Through A Knife Surface," represents an ex vivo artifact. The purpose of this study was to prospectively investigate the presence and frequency of these free-floating tumor cell clusters in surgically resected lung cancer specimens and their possible relation to gross examination procedures...
June 15, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28620260/the-positive-expression-of-genotype-vii-newcastle-disease-virus-malaysian-isolate-in-japanese-quails-coturnix-coturnix-japonica
#11
Lizma Felisha Mazlan, Noor Farhana Bachek, Siti Nor Azizah Mahamud, Lokman Hakim Idris, Tan Sheau Wei, Abdul Rahman Omar, Mohd Hezmee Mohd Noor
AIM: Genotype VII Newcastle disease virus (NDV) is the most predominant NDV strains that circulating in Malaysia; thus, this study was aimed to determine the susceptibility of Japanese quails toward genotype VII NDV. Clinical signs, gross pathological lesions of organs, positive detection of virus in organs and cloacal swabs, as well as the expression of the antibody titer, were used as parameters to assess the susceptibility of Japanese quails following infection of genotype VII NDV...
May 2017: Veterinary World
https://www.readbyqxmd.com/read/28619543/circumferential-three-dimensional-printed-tracheal-grafts-research-model-feasibility-and-early-results
#12
Faiz Y Bhora, Erik E Lewis, Sadiq S Rehmani, Adil Ayub, Wissam Raad, Adnan M Al-Ayoubi, Robert S Lebovics
BACKGROUND: Methods for tracheal graft research have presented persistent challenges to investigators, and three-dimensional (3D)-printed biosynthetic grafts offer one potential development platform. We aimed to develop an efficient research platform for customizable circumferential 3D-printed tracheal grafts and evaluate feasibility and early structural integrity with a large-animal model. METHODS: Virtual 3D models of porcine subject tracheas were generated using preoperative computed tomography scans...
June 13, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28619022/effect-of-low-magnitude-different-frequency-whole-body-vibration-on-subchondral-trabecular-bone-microarchitecture-cartilage-degradation-bone-cartilage-turnover-and-joint-pain-in-rabbits-with-knee-osteoarthritis
#13
Wang Junbo, Liu Sijia, Chen Hongying, Liu Lei, Wang Pu
BACKGROUD: Whole-body vibration(WBV) has been suggested for the prevention of subchondral bone loss of knee osteoarthritis (OA) . This study examined the effects of different frequency of whole-body vibration on subchondral trabecular bone microarchitecture, cartilage degradation and metabolism of the tibia and femoral condyle bone, and joint pain in an anterior cruciate ligament transection (ACLT)-induced knee osteoarthritisrabbit model. METHOD: Ninety adult rabbits were divided into six groups: all groups received unilateral ACLT; Group 1, ACLT only; Group 2, 5 Hz WBV; Group 3, 10 Hz WBV; Group 4, 20 Hz WBV; Group 5, 30 Hz WBV; and Group 6, 40 Hz WBV...
June 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28615898/teratogenic-effects-of-carbamazepine-in-mice
#14
Manna Jose, Harikrishnan Vijayakumar Sreelatha, Manjula Valiyamattathil James, Sabareeswaran Arumughan, Sanjeev Varghese Thomas
OBJECTIVES: The aim of this study was to determine the teratogenic effects of carbamazepine (CBZ) in BALB/c mice. MATERIALS AND METHODS: Mature female and male BALB/c mice (25-30 g) were used for all experiments. After standardization of administration and dose of CBZ, animals in the CBZ-treated groups (CBZ 450 mg/kg and 600 mg/kg) were fed on medicinal diet. The dams in the control group were mated on the same day as that of the CBZ-treated dams. After cesarean section (CS), fetal viability status and weights were recorded...
April 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28615833/prevalence-and-organwise-distribution-of-sarcocystiosis-in-buffaloes-of-mohali-punjab
#15
Khadim Hussain Dar, Mohd Mansoor Bhat, Majid Shafi
The study was carried at Mirha Exports private limited at Mohali, Punjab, from December 2012 to May 2013 during which 1000 buffaloes of 2-3 years of age slaughtered for meat purposes were screened for the Sarcocystis species. Most of the animals examined at anti-mortem appeared normal and clinically healthy. However, at slaughtering, the gross and microscopic examination of representative samples of striated muscles collected from slaughtered buffaloes revealed 95.50 % prevalence of Sarcocystis species. Out of 1000 samples examined, 955 samples (95...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28615377/after-mexico-implemented-a-tax-purchases-of-sugar-sweetened-beverages-decreased-and-of-water-increased-difference-by-place-of-residence-household-composition-and-income-level
#16
M Arantxa Colchero, Mariana Molina, Carlos M Guerrero-López
Background: In January 2014, Mexico implemented a tax on sugar-sweetened beverage (SSB) purchases of 1 peso/L.Objective: We examined the heterogeneity of changes in nonalcoholic beverage (SSB and bottled water) purchases after the tax was implemented by household income, urban and rural strata, and household composition.Methods: We used 4 rounds of the National Income and Expenditure Surveys: 2008, 2010, 2012, and 2014. Changes in purchases in per capita liters per week were estimated with the use of 2-part models to adjust for nonpurchases...
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615374/a-cross-sectional-survey-in-rural-bihar-india-indicates-that-nutritional-status-diet-and-stimulation-are-associated-with-motor-and-mental-development-in-young-children
#17
Leila M Larson, Melissa F Young, Usha Ramakrishnan, Amy Webb Girard, Pankaj Verma, Indrajit Chaudhuri, Sridhar Srikantiah, Reynaldo Martorell
Background: Many malnourished children in resource-poor settings fail to fulfill their developmental potential.Objectives: The objectives of this analysis were to examine the nutritional, psychosocial, environmental, and household correlates of child development in Bihar, India, and identify mediators between dietary diversity and mental development.Methods: Using 2-stage cluster randomized sampling, we surveyed 4360 households with children 6-18 mo of age in the West Champaran district of Bihar. We measured motor and mental development with the use of the Developmental Milestones Checklist II...
June 14, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28615133/platelet-rich-plasma-with-keratinocytes-and-fibroblasts-enhance-healing-of-full-thickness-wounds
#18
Jia Xian Law, Shiplu Roy Chowdhury, Aminuddin Bin Saim, Ruszymah Bt Hj Idrus
Advances in tissue engineering led to the development of various tissue-engineered skin substitutes (TESS) for the treatment of skin injuries. The majority of the autologous TESS required lengthy and costly cell expansion process to fabricate. In this study, we determine the possibility of using a low density of human skin cells suspended in platelet-rich plasma (PRP)-enriched medium to promote the healing of full-thickness skin wounds. To achieve this, full-thickness wounds of size 1.767 cm(2) were created at the dorsum part of nude mice and treated with keratinocytes (2 × 10(4) cells/cm(2)) and fibroblasts (3 × 10(4) cells/cm(2)) suspended in 10% PRP-enriched medium...
June 7, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28614488/social-inequalities-in-maternal-mortality-among-the-provinces-of-ecuador
#19
Antonio Sanhueza, Jakeline Calle Roldán, Paulina Ríos-Quituizaca, Maria Cecilia Acuña, Isabel Espinosa
Objective: This study set out to describe the association between the maternal mortality ratio (MMR) estimates and a set of socioeconomic indicators and compute the MMR inequalities among the provinces of Ecuador. Methods: A cross-sectional ecological study was conducted, using data for 2014 from the country's 24 provinces. The MMR estimate was calculated for each province, as well as the association and its strength between MMR and specific socioeconomic indicators...
June 8, 2017: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/28611946/patients-with-multifocal-macroscopic-papillary-thyroid-carcinoma-have-a-low-risk-of-recurrence-at-early-follow-up-after-total-thyroidectomy-and-radioactive-iodine-treatment
#20
Amanda La Greca, Bin Xu, Ronald Ghossein, R Michael Tuttle, Mona M Sabra
BACKGROUND: Multifocal thyroid cancer involvement is a common presentation in papillary thyroid cancer. The risk of recurrence of intrathyroidal multifocal papillary microcarcinoma (<1 cm) is documented to be low. However, the risk of recurrence of multifocal macroscopic thyroid cancer is not known. Prior studies have suggested that both the number of foci and the presence of nodal involvement at diagnosis are important predictors of recurrence in multifocal papillary thyroid carcinoma (PTC)...
February 2017: European Thyroid Journal
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