keyword
MENU ▼
Read by QxMD icon Read
search

Bo

keyword
https://www.readbyqxmd.com/read/29342237/the-roles-of-subdivisions-of-human-insula-in-emotion-perception-and-auditory-processing
#1
Yang Zhang, Wenjing Zhou, Siyu Wang, Qin Zhou, Haixiang Wang, Bingqing Zhang, Juan Huang, Bo Hong, Xiaoqin Wang
Previous studies have shown insular activations involving sensory, motor, and affective processing. However, the functional roles of subdivisions within the human insula are still not well understood. In the present study, we used intracranial electroencephalography and electrical cortical stimulation to investigate the causal roles of subdivisions of the insula in auditory emotion perception in epilepsy patients implanted with depth electrodes in this brain region. The posterior and the anterior subdivisions of the human insula, identified based on structural and functional analyses, showed distinct response properties to auditory emotional stimuli...
January 12, 2018: Cerebral Cortex
https://www.readbyqxmd.com/read/29342205/correction-cholecystectomy-can-increase-the-risk-of-colorectal-cancer-a-meta-analysis-of-10-cohort-studies
#2
Yong Zhang, Hao Liu, Li Li, Min Ai, Zheng Gong, Yong He, Yunlong Dong, Shuanglan Xu, Jun Wang, Bo Jin, Jianping Liu, Zhaowei Teng
[This corrects the article DOI: 10.1371/journal.pone.0181852.].
2018: PloS One
https://www.readbyqxmd.com/read/29342171/health-behavior-associated-with-liver-enzymes-among-obese-korean-adolescents-2009-2014
#3
Eun-Young Lee, Hwa Young Choi, Hyunsoon Cho, Bo Hyun Kim, Moran Ki
AIMS: Obesity is major risk factor for liver health. This study aimed to clarify whether specific health behaviors were associated with liver function in obese adolescents in Korea. METHODS: Based on national school health examination data from 2009 to 2014, 25,142 obese or overweight students were examined for aspartate transaminase and alanine transaminase levels, and health behaviors. Multiple logistic regression was used to calculate the odds ratio for liver enzyme elevation...
2018: PloS One
https://www.readbyqxmd.com/read/29341876/probing-and-characterizing-the-high-specific-sequences-of-ssdna-aptamer-against-sgiv-infected-cells
#4
Pengfei Li, Qing Yu, Lingli Zhou, Dexin Dong, Shina Wei, Hanzheng Ya, Bo Chen, Qiwei Qin
As the major viral pathogen of grouper aquaculture, Singapore grouper iridovirus (SGIV) has caused great economic losses in China and Southeast Asia. In the previous study, we have generated highly specific ssDNA aptamers against SGIV-infected grouper spleen cells (GS) by Systematic Evolution of Ligands by Exponential Enrichment technology (SELEX), in which Q2 had the highest binding affinity of 16.43 nM. In this study, we would try to identify the specific sequences in the aptamer Q2 that exhibited the high binding affinity to SGIV-infected cells by truncating the original Q2 into some different specific segments...
January 13, 2018: Virus Research
https://www.readbyqxmd.com/read/29341672/helicase-stepping-investigated-with-one-nucleotide-resolution-fluorescence-resonance-energy-transfer
#5
Wenxia Lin, Jianbing Ma, Daguan Nong, Chunhua Xu, Bo Zhang, Jinghua Li, Qi Jia, Shuoxing Dou, Fangfu Ye, Xuguang Xi, Ying Lu, Ming Li
Single-molecule Förster resonance energy transfer is widely applied to study helicases by detecting distance changes between a pair of dyes anchored to overhangs of a forked DNA. However, it has been lacking single-base pair (1-bp) resolution required for revealing stepping kinetics of helicases. We designed a nanotensioner in which a short DNA is bent to exert force on the overhangs, just as in optical or magnetic tweezers. The strategy improved the resolution of Förster resonance energy transfer to 0.5 bp, high enough to uncover differences in DNA unwinding by yeast Pif1 and E...
September 29, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29341636/pair-potential-with-submillikelvin-uncertainties-and-nonadiabatic-treatment-of-the-halo-state-of-the-helium-dimer
#6
Michał Przybytek, Wojciech Cencek, Bogumił Jeziorski, Krzysztof Szalewicz
The pair potential for helium is computed with accuracy improved by an order of magnitude relative to the best previous determination. For the well region, its uncertainties are now below 1 millikelvin. The main improvement is due to the use of explicitly correlated wave functions at the nonrelativistic Born-Oppenheimer (BO) level of theory. The diagonal BO and the relativistic corrections are obtained from large full configuration interaction calculations. Nonadiabatic perturbation theory is used to predict the properties of the halo state of the helium dimer...
September 22, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29341624/regio-and-enantioselective-organocatalytic-friedel-crafts-alkylation-of-4-aminoindoles-at-the-c7-position
#7
Wen Xun, Bo Xu, Bo Chen, Shanshui Meng, Albert S C Chan, Fayang G Qiu, Junling Zhao
A chiral phosphoric acid catalyzed highly regio- and enantioselective Friedel-Crafts alkylation at the indole C7-position was developed via the introduction of an alkylamine moiety at the C4-position of the indole ring. The methodology is applicable to a wide range of 4-aminoindoles and β,γ-unsaturated α-ketimino esters to furnish the corresponding C7-position functionalized chiral indole derivatives in high yields with moderate to excellent enantioselectivities. Furthermore, the α-ketimino ester moiety in the products is a versatile building block and enables many further transformations...
January 17, 2018: Organic Letters
https://www.readbyqxmd.com/read/29341604/ce3-doping-to-modulate-photoluminescence-kinetics-for-efficient-cspbbr3-nanocrystals-based-light-emitting-diodes
#8
Jisong Yao, Jing Ge, Bo-Ning Han, Kun-Hua Wang, Hong-Bin Yao, Hao-Lei Yu, Jian-Hai Li, Bai-Sheng Zhu, Jizhong Song, Chen Chen, Qun Zhang, Haibo Zeng, Yi Luo, Shu-Hong Yu
Inorganic perovskite CsPbBr3 nanocrystals (NCs) are emerging, highly attractive light emitters with high color purity and good thermal stability for light-emitting diodes (LEDs). Their high photo/electroluminescence efficiencies are very important for fabricating efficient LEDs. Here, we propose a novel strategy to enhance the photo/electroluminescence efficiency of CsPbBr3 NCs through doping of heterovalent Ce3+ ions via a facile hot-injection method. The Ce3+ cation was chosen as the dopant for CsPbBr3 NCs by virtue of its similar ion radius and formation of higher energy level of conduction band with bromine in comparison with the Pb2+ cation to maintain the integrity of perovskite structure without introducing additional trap states...
January 17, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29341439/therapeutic-benefits-of-cd90-negative-cardiac-stromal-cells-in-rats-with-a-30-day-chronic-infarct
#9
Deliang Shen, Miaoda Shen, Hongxia Liang, Junnan Tang, Bo Wang, Chuang Liu, Peiwen Wang, Jianzeng Dong, Ling Li, Jinying Zhang, Thomas G Caranasos
Cardiac stromal cells (CSCs) can be derived from explant cultures, and a subgroup of these cells is viewed as cardiac mesenchymal stem cells due to their expression of CD90. Here, we sought to determine the therapeutic potential of CD90-positive and CD90-negative CSCs in a rat model of chronic myocardial infarction. We obtain CD90-positive and CD90-negative fractions of CSCs from rat myocardial tissue explant cultures by magnetically activated cell sorting. In vitro, CD90-negative CSCs outperform CD90-positive CSCs in tube formation and cardiomyocyte functional assays...
January 17, 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29341420/transgenic-mice-specifically-expressing-amphiregulin-in-white-adipose-tissue-showed-less-adipose-tissue-mass
#10
Bo Yang, Takahiro Kumoto, Takeshi Arima, Minako Nakamura, Yohei Sanada, Thanutchaporn Kumrungsee, Yusuke Sotomaru, Masayuki Shimada, Noriyuki Yanaka
To determine adipocytokines that play a regulatory role during obesity development, we explored the genes that encode growth factors and investigated the physiological functions for adipose tissue development. Here, we isolated amphiregulin (Areg) gene whose expression was significantly up-regulated in obese adipose tissues. Areg mRNA level was positively correlated with macrophage marker gene expression in adipose tissues in vivo. Unexpectedly, Areg transgenic mice showed less adipose tissue mass with increased mRNA expression levels of Tnf-α and peroxisome proliferator-activated receptor γ coactivator 1α (Pgc-1α) and delayed white adipose tissue development during the convalescent stage in a dextran sodium sulfate-induced colitis model...
January 17, 2018: Genes to Cells: Devoted to Molecular & Cellular Mechanisms
https://www.readbyqxmd.com/read/29340887/toward-evidence-based-chinese-medicine-status-quo-opportunities-and-challenges
#11
Yao-Long Chen, Chen Zhao, Li Zhang, Bo Li, Chuan-Hong Wu, Wei Mu, Jia-Ying Wang, Ke-Hu Yang, You-Ping Li, Chiehfeng Chen, Yong-Yan Wang, Chen Wang, Zhao-Xiang Bian, Hong-Cai Shang
How to test the treatments of Chinese medicine (CM) and make them more widely accepted by practitioners of Western medicine and the international healthcare community is a major concern for practitioners and researchers of CM. For centuries, various approaches have been used to identify and measure the efficacy and safety of CM. However, the high-quality evidence related to CM that produced in China is still rare. Over the recent years, evidence-based medicine (EBM) has been increasingly applied to CM, strengthening its theoretical basis...
January 16, 2018: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29340815/comparison-between-submucosal-tunneling-endoscopic-resection-and-video-assisted-thoracoscopic-enucleation-for-esophageal-submucosal-tumors-originating-from-the-muscularis-propria-layer-a-randomized-controlled-trial
#12
Ningli Chai, Chen Du, Ying Gao, Xiaotong Niu, Yaqi Zhai, Enqiang Linghu, Yang Liu, Bo Yang, Zhongsheng Lu, Zhenjuan Li, Xiangdong Wang, Ping Tang
BACKGROUND AND AIMS: Surgical resection is considered the first treatment option for submucosal tumors (SMTs) originating from the muscularis propria layer while submucosal tunneling endoscopic resection (STER) is proved to be a safe and effective method for treating SMTs. This study aimed to compare video-assisted thoracoscopic enucleation (VATE) with STER for treating esophageal SMTs. METHODS: Sixty-six patients with small esophageal SMTs were prospectively randomized from July 2014 to December 2015...
January 16, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29340571/comparison-of-physician-visual-assessment-with-quantitative-coronary-angiography-in-assessment-of-stenosis-severity-in-china
#13
Haibo Zhang, Lin Mu, Shuang Hu, Brahmajee K Nallamothu, Alexandra J Lansky, Bo Xu, Georgios Bouras, David J Cohen, John A Spertus, Frederick A Masoudi, Jeptha P Curtis, Runlin Gao, Junbo Ge, Yuejin Yang, Jing Li, Xi Li, Xin Zheng, Yetong Li, Harlan M Krumholz, Lixin Jiang
Importance: Although physician visual assessment (PVA) of stenosis severity is a standard clinical practice to support decisions for coronary revascularization, there are concerns about its accuracy. Objective: To compare PVA with quantitative coronary angiography (QCA) as a means of assessing stenosis severity among patients undergoing percutaneous coronary intervention (PCI) in China. Design, Setting, and Participants: A cross-sectional study (2012-2013) of a random subset of 1295 patients from the China Patient-centered Evaluative Assessment of Cardiac Events (PEACE) Prospective PCI Study was carried out...
January 16, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29340423/total-synthesis-of-five-natural-eremophilane-type-sesquiterpenoids
#14
Zhe Meng, Bo Liu
The first total syntheses of five natural eremophilane-type sesquiterpenoids were achieved in 4-12 steps via a common synthetic intermediate. The syntheses feature a double Michael addition, Robinson annulation, α-enolization of an unsaturated ketone, and Pd-catalyzed Suzuki coupling reaction to install the side chain. This synthetic strategy could be easily extended to other eremophilane-type sesquiterpenoids with similar bicyclic skeletons.
January 17, 2018: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29340394/highly-selective-hydrosilylation-of-olefins-and-acetylenes-by-platinum-0-complexes-bearing-bulky-n-heterocyclic-carbene-ligands
#15
P Żak, M Bołt, M Kubicki, C Pietraszuk
Platinum complexes bearing bulky N-heterocyclic carbene (NHC) ligands, i.e., [Pt(IPr*)(dvtms)] (where, IPr* = 1,3-bis{2,6-bis(diphenylmethyl)-4-methylphenyl}imidazol-2-ylidene) and [Pt(IPr*OMe)(dvtms)] (where, IPr*OMe = 1,3-bis{2,6-bis(diphenylmethyl)-4-methoxyphenyl}imidazol-2-ylidene, dvtms = divinyltetramethyldisiloxane) catalyse nearly quantitatively and highly or completely the selective hydrosilylation of terminal olefins as well as terminal or internal acetylenes.
January 17, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29340096/crispr-cas9-mediated-reversibly-immortalized-mouse-bone-marrow-stromal-stem-cells-bmscs-retain-multipotent-features-of-mesenchymal-stem-cells-mscs
#16
Xue Hu, Li Li, Xinyi Yu, Ruyi Zhang, Shujuan Yan, Zongyue Zeng, Yi Shu, Chen Zhao, Xingye Wu, Jiayan Lei, Yasha Li, Wenwen Zhang, Chao Yang, Ke Wu, Ying Wu, Liping An, Shifeng Huang, Xiaojuan Ji, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Wei Liu, Bo Huang, Yixiao Feng, Bo Zhang, Rex C Haydon, Hue H Luu, Russell R Reid, Michael J Lee, Jennifer Moriatis Wolf, Zebo Yu, Tong-Chuan He
Mesenchymal stem cells (MSCs) are multipotent non-hematopoietic progenitor cells that can undergo self-renewal and differentiate into multi-lineages. Bone marrow stromal stem cells (BMSCs) represent one of the most commonly-used MSCs. In order to overcome the technical challenge of maintaining primary BMSCs in long-term culture, here we seek to establish reversibly immortalized mouse BMSCs (imBMSCs). By exploiting CRISPR/Cas9-based homology-directed-repair (HDR) mechanism, we target SV40T to mouse Rosa26 locus and efficiently immortalize mouse BMSCs (i...
December 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29340086/up-regulation-of-lncrna-snhg1-indicates-poor-prognosis-and-promotes-cell-proliferation-and-metastasis-of-colorectal-cancer-by-activation-of-the-wnt-%C3%AE-catenin-signaling-pathway
#17
Yuping Zhu, Bo Li, Zhuo Liu, Lai Jiang, Gang Wang, Min Lv, Dechuan Li
Recently, the lncRNA small nucleolar RNA host gene (SNHG1) has been exhibited to be upregulated, which plays a crucial role in the development and prognosis of several cancers. However, the role of the biology and clinical significance of SNHG1 in the tumorigenesis of colorectal cancer (CRC) has rarely been reported. In this work, we firstly found that SNHG1 expression levels were upregulated aberrantly in colorectal cancer tissues and colorectal cancer cell lines. By Kaplan-Meier survival analysis, patients with high SNHG1 expression level had poorer overall survival (OS) and progression-free survival (PFS) than those with low SNHG1 expression...
December 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29340064/antitumor-activity-of-resveratrol-against-human-osteosarcoma-cells-a-key-role-of-cx43-and-wnt-%C3%AE-catenin-signaling-pathway
#18
Da Xie, Gui-Zhou Zheng, Peng Xie, Qi-Hao Zhang, Fei-Xiang Lin, Bo Chang, Qin-Xiao Hu, Shi-Xin Du, Xue-Dong Li
Osteosarcoma is a high-grade bone sarcoma with strong invasive ability. However, treatment with traditional chemotherapeutic drugs is limited by low tolerability and side effects. Resveratrol has been reported previously to have selective antitumor effect on various tumor cells while little is known about its effects and underlying mechanism in osteosarcoma biology. In this study, we found that resveratrol inhibits proliferation and glycolysis, induces apoptosis and reduces the invasiveness of U2-OS cells in vitro...
December 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29340043/clinical-significance-of-yap1-activation-in-head-and-neck-squamous-cell-carcinoma
#19
Young-Gyu Eun, Dongjin Lee, Young Chan Lee, Bo Hwa Sohn, Eui Hyun Kim, Sun Young Yim, Kee Hwan Kwon, Ju-Seog Lee
By analyzing the genomic data of head and neck squamous cell cancer (HNSCC), we investigated clinical significance of YAP1 activation. Copy number and mRNA expression of YAP1 were analyzed together to assess clinical relevance of YAP1 activation in HNSCC. The clinical significance of YAP1 activation was further validated in four independent test cohorts. We also assessed the correlation of YAP1 activation with genomic alterations such as copy number alteration, somatic mutation, and miRNA expression. The YAP1-activated (YA) subgroup showed worse prognosis for HNSCC as tested and validated in five cohorts...
December 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29339622/identification-of-fouling-mechanisms-in-mbrs-at-constant-flowrate-model-applications-and-sem-edx-characterizations
#20
Bo Hu, Xingtao Zuo, Juan Xiong, Huimeng Yang, Menghua Cao, Shuili Yu
A fundamental understanding of fouling mechanisms is critical to improving filtration operations. The performance of four parallel membrane bioreactors (MBRs) with different sludge retention times (SRTs) was monitored during long-term constant flowrate filtration. The characteristics of the membrane and transmembrane pressure (TMP) profiles obtained were studied to demonstrate fouling mechanisms. Both classical blocking models and their combined models were evaluated. The intermediate model provided very good agreement with all the TMP data...
January 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
keyword
keyword
88832
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"