keyword
https://read.qxmd.com/read/38476312/dexmedetomidine-prevents-spatial-learning-and-memory-impairment-induced-by-chronic-rem-sleep-deprivation-in-rats
#21
JOURNAL ARTICLE
Wen-Hao Zhang, Yi-Ning Yan, John P Williams, Jian Guo, Bao-Feng Ma, Jian-Xiong An
UNLABELLED: The study was attempted to investigate the effect on and mechanisms of action of dexmedetomidine with regard to learning and memory impairment in rats with chronic rapid eye movement (REM) sleep deprivation. A total of 50 male Sprague Dawley rats were randomly divided into five groups. Modified multiple platform method was conducted to cause the sleep deprivation of rats. Dexmedetomidine and midazolam were administered by intraperitoneal injection. Learning and memory ability was assessed through Morris water maze...
July 2023: Sleep and Biological Rhythms
https://read.qxmd.com/read/38473083/advances-in-the-clinical-diagnostics-to-equine-back-pain-a-review-of-imaging-and-functional-modalities
#22
REVIEW
Natalia Domańska-Kruppa, Małgorzata Wierzbicka, Elżbieta Stefanik
Back pain is common in ridden horses. Back diseases in horses include Impinging Dorsal Spinous Processes, Ventral Spondylosis, Osteoarthritis of Articular Process, Intervertebral Discs Disease, Vertebral Fractures, Conformational Abnormalities, Desmopathy of the Supraspinous Ligament, Desmopathy of the Intraspinous Ligament, and Longissimus Muscle Strain. Back pain may also develop as a result of lameness (particularly hindlimb lameness). A poorly fitting saddle and an unbalanced rider are also considered important factors influencing the development of back pain in horses...
February 23, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38463986/characterization-of-the-three-dimensional-synaptic-and-mitochondrial-nanoarchitecture-within-glutamatergic-synaptic-complexes-in-postmortem-human-brain-via-focused-ion-beam-scanning-electron-microscopy
#23
Jill R Glausier, Cedric Bouchet-Marquis, Matthew Maier, Tabitha Banks-Tibbs, Ken Wu, Jiying Ning, Darlene Melchitzky, David A Lewis, Zachary Freyberg
Glutamatergic synapses are the primary site of excitatory synaptic signaling and neural communication in the cerebral cortex. Electron microscopy (EM) studies in non-human model organisms have demonstrated that glutamate synaptic activity and functioning are directly reflected in quantifiable ultrastructural features. Thus, quantitative EM analysis of glutamate synapses in ex vivo preserved human brain tissue has the potential to provide novel insight into in vivo synaptic functioning. However, factors associated with the acquisition and preservation of human brain tissue have resulted in persistent concerns regarding the potential confounding effects of antemortem and postmortem biological processes on synaptic and sub-synaptic ultrastructural features...
February 28, 2024: bioRxiv
https://read.qxmd.com/read/38452644/cervicothoracic-c-6-c-7-t-1-spina-bifida-occulta-a-case-report
#24
Soheil Mirzaei, Maryam Khoshkholghsima, Amir Sabaghzadeh, Hoshmand Zarei Kurdkandi
INTRODUCTION: Spina bifida (SB), as one of the spine abnormalities, is caused by incomplete closure of the neural tube and generally includes two types: open and closed. This study aims to introduce one of the rare cases of closed SB. CASE PRESENTATION: A 34-year-old male patient was admitted to the hospital with neck pain. Radiographic and computed tomography (CT) imaging revealed bifid spinous processes from C6 to T1 vertebrae, indicative of a rare case of closed SB in the cervicothoracic region...
March 5, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38441155/a-novel-surgical-indication-for-scheuermann-s-kyphosis
#25
JOURNAL ARTICLE
Jason J Haselhuhn, Kari Odland, Paul Brian O Soriano, Kristen E Jones, David W Polly
Scheuermann kyphosis can be treated surgically to restore proper sagittal alignment. Thoracic curves >70° are typically indicated for surgical intervention. However, patients who have reached their natural limit of compensatory lumbar hyperlordosis are at risk of accelerated degeneration. This can be determined by comparing lumbar lordosis on standing neutral radiographs and supine extension radiographs. Minimal additional lordosis in extension compared with neutral, abutment of the spinous processes, or greater lumbar lordosis standing than with attempted extension suggest the patient is maximally compensated...
March 1, 2024: Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews
https://read.qxmd.com/read/38433470/a-spinal-mri-image-segmentation-method-based-on-improved-swin-unet
#26
JOURNAL ARTICLE
Jie Cao, Jiacheng Fan, Chin-Ling Chen, Zhenyu Wu, Qingxuan Jiang, Shikai Li
As the number of patients increases, physicians are dealing with more and more cases of degenerative spine pathologies on a daily basis. To reduce the workload of healthcare professionals, we propose a modified Swin-UNet network model. Firstly, the Swin Transformer Blocks are improved using a residual post-normalization and scaling cosine attention mechanism, which makes the training process of the model more stable and improves the accuracy. Secondly, we use the log-space continuous position biasing method instead of the bicubic interpolation position biasing method...
March 3, 2024: Network: Computation in Neural Systems
https://read.qxmd.com/read/38432788/the-frequency-and-presentation-of-upper-thoracic-spinous-process-deviations-their-relationship-to-articular-morphology-and-the-potential-influence-on-static-palpation-techniques
#27
JOURNAL ARTICLE
Christopher Yelverton, Bernhard Zipfel, Scott Williams, Cynthia Peterson
BACKGROUND: Static palpation of vertebral spinous process deviations from the midline are often utilized by manual therapists as a means to determine area for treatment of manipulable lesions. Previous research has discussed the diagnostic validity of this technique, but no correlation to vertebral morphology has been presented. AIM: To evaluate the frequency and presentation of vertebral spinous process deviations and their relationship with articular morphology, and the impact this may have in terms of static palpation techniques in the upper thoracic spine...
January 2024: Journal of Bodywork and Movement Therapies
https://read.qxmd.com/read/38424355/sub-gluteal-ligation-of-the-internal-pudendal-vein-for-management-of-veno-occlusive-erectile-dysfunction-shaeer-s-vein-ligation-i-the-cadaveric-study
#28
JOURNAL ARTICLE
Osama Shaeer, Ehab A A El-Shaarawy, Hossam Y Emam, Islam Elsisi, Eslam Sokar, Kamal Shaeer
Vein ligation for veno-occlusive erectile dysfunction is being abandoned due to the recurrence rate. Among the reasons for failure is inability to ligate the deep system of veins; the internal pudendal vein. The vein exits the pelvis in the gluteal region, from the lesser sciatic foramen to the greater sciatic foramen, coursing over the ischial spine and sacro-spinous ligament, under the gluteus maximus. This work aims to verify feasibility of the first surgical procedure to ligate the internal pudendal vein through the gluteal approach...
February 29, 2024: International Journal of Impotence Research
https://read.qxmd.com/read/38419134/morphological-examination-of-abdominal-vertebral-bodies-from-grass-carp-using-high-resolution-micro-ct-scans
#29
JOURNAL ARTICLE
Meir M Barak, James Schlott, Laura Gundersen, Giovanni Diaz, Vanessa Rhee, Naomi Villoth, Alexandra Ferber, Salvatore Blair
The vertebral column, a defining trait of all vertebrates, is organized as a concatenated chain of vertebrae, and therefore its support to the body depends on individual vertebral morphology. Consequently, studying the morphology of the vertebral centrum is of anatomical and clinical importance. Grass carp (GC) is a member of the infraclass Teleostei (teleost fish), which accounts for the majority of all vertebrate species; thus, its vertebral anatomical structure can help us understand vertebrate development and vertebral morphology...
February 28, 2024: Journal of Anatomy
https://read.qxmd.com/read/38414594/novel-approach-of-ultrasound-guided-lateral-recess-block-for-a-patient-with-lateral-recess-stenosis-a-case-report
#30
Jiao Yang, Xin-Ling Li, Qing-Bing Li
BACKGROUND: Ultrasound guide technology, which can provide real-time visualization of the needle tip and tissues and avoid many adverse events, is widely used in minimally invasive therapy. However, the studies on ultrasound-guided Lateral recess block (LRB) are limited, this is probably because there is no recognized standard method for ultrasound scanning. This study aimed to evaluate the effect of ultrasound-guided LRB in patients with lateral recess stenosis (LRS). CASE SUMMARY: A 65-year-old patient complained of low back pain accompanied occasionally by pain and numbness in the left lower limb...
February 16, 2024: World Journal of Clinical Cases
https://read.qxmd.com/read/38413237/the-influence-of-spinous-process-union-on-clinical-outcomes-after-spinous-process-osteotomy-for-lumbar-spinal-stenosis-after-2-years-a-secondary-analysis-from-the-nordsten-study
#31
JOURNAL ARTICLE
Sondre Hagerup, Jens Ivar Brox, Hasan Banitalebi, Kari Indrekvam, Tor Åge Myklebust, Erland Hermansen
BACKGROUND: Lumbar spinal stenosis is a prevalent and increasingly important cause of low back pain, leg pain, and walking impairment. Minimally invasive decompressive techniques such as spinous process (SP) osteotomy have become more common in recent years. The main aim of this study was to investigate the proportion of complete SP union and whether complete radiological healing after the osteotomy is associated with superior clinical outcome after 2 years. METHODS: In this retrospective cohort study, 149 patients were included from the Spinal Stenosis Trial, a part of the NORwegian Degenerative spondylolisthesis and spinal STENosis study...
February 27, 2024: International Journal of Spine Surgery
https://read.qxmd.com/read/38404727/strontium-ranelate-retards-disc-degradation-and-improves-endplate-and-bone-micro-architecture-in-ovariectomized-rats-with-lumbar-fusion-induced-adjacent-segment-disc-degeneration
#32
JOURNAL ARTICLE
Qi Sun, Fang Liu, Jiakang Fang, Qiangqiang Lian, Yunpeng Hu, Xinyu Nan, Fa-Ming Tian, Guochuan Zhang, Dianwen Qi, Liu Zhang, Jingwen Zhang, Yang Luo, Zuzhuo Zhang, Zhuang Zhou
OBJECTIVES: Adjacent segment disc degeneration (ASDD) is one of the long-term sequelae of spinal fusion, which is more susceptible with osteoporosis. As an anti-osteoporosis drug, strontium ranelate (SR) has been reported to not only regulate bone metabolism but also cartilage matrix formation. However, it is not yet clear whether SR has a reversal or delaying effect on fusion-induced ASDD in a model of osteoporosis. MATERIALS AND METHODS: Fifth three-month-old female Sprague-Dawley rats that underwent L4-L5 posterolateral lumbar fusion (PLF) with spinous-process wire fixation 4 weeks after bilateral ovariectomy (OVX) surgery...
March 2024: Bone Reports
https://read.qxmd.com/read/38403019/navigated-simultaneous-lateral-minimally-invasive-tubular-and-posterior-mini-open-access-for-removal-and-revision-of-triangular-sacroiliac-joint-implants-technical-note
#33
JOURNAL ARTICLE
Shahaan S Razak, Ghani Haider, Timothy West, Ghusn AlSideiri, Justin Massengale
BACKGROUND: Sacroiliac joint (SIJ) fusion, to treat back pain caused by SIJ dysfunction, can employ open or minimally invasive surgery (MIS) techniques and either cylindrical (screw-shaped) or triangular (wedge-shaped) implants. Fusion nonunion sometimes explains recurrent SIJ pain following fusion and occasionally requires hardware revision. MIS revision minimizes patient pain, infection, and disability, but due to the triangular implant size and form factor, implant removal can present challenges for MIS access during the explantation and achieving good bony purchase for re-instrumentation...
February 23, 2024: World Neurosurgery
https://read.qxmd.com/read/38382241/evaluating-postcranial-macromorphoscopic-traits-to-estimate-population-variation-among-modern-south-africans
#34
JOURNAL ARTICLE
N P Bothma, E N L'abbé, L Liebenberg
Population overlap and the variation within and among populations have been globally observed but is often difficult to quantify. To achieve this, numerous different methods need to be explored and validated to assist with the creation of an accurate biological profile. The current lack of databases for postcranial macromorphoscopic traits indicates the need to further investigate if the method can be employed repeatably in a forensic context. The current study aimed to assess the prevalence of eleven postcranial macromorphoscopic traits in a South African sample...
February 7, 2024: Forensic Science International
https://read.qxmd.com/read/38379241/international-survey-of-equine-orthopaedic-specialists-reveals-diverse-treatment-strategies-for-horses-with-overriding-spinous-processes
#35
JOURNAL ARTICLE
Dorothea Treß, Christoph Lischer, Roswitha Merle, Anna Ehrle
BACKGROUND: Overriding spinous processes, also known as 'kissing spines', are one of the most common causes of back pain in horses. The aim of this study was to investigate which options for diagnosis and treatment are preferred by equine orthopaedic specialists and assess which techniques are used for local injection. METHODS: An online survey was distributed among members of the European/American College of Veterinary Surgeons, the European/American College of Veterinary Sports Medicine and Rehabilitation, the International Society of Equine Locomotor Pathology and nationally recognised advanced equine orthopaedic practitioners...
February 20, 2024: Veterinary Record
https://read.qxmd.com/read/38373811/post-traumatic-lumbar-nerve-root-entrapment-into-the-spinous-process-of-the-lumbar-spine
#36
JOURNAL ARTICLE
Diwakar Shankar, Mohammad Kaif, Krishna Kumar
Thoracolumbar fractures constitute a significant portion of spinal trauma, accounting for 15-20% of the cases. These fractures, caused by high-impact injuries, may involve tears of the posterior ligamentous complex, presenting a high chance of neurological injury ranging from dural tears to spinal root avulsion. This case report discusses a rare occurrence of avulsion of lumbosacral nerve roots posteriorly, becoming entrapped in the fractured spinous process of the L2 lumbar vertebra, leading to cauda equina syndrome following trauma and its implications during surgery...
February 19, 2024: BMJ Case Reports
https://read.qxmd.com/read/38369553/clinical-and-radiological-outcomes-of-non-window-type-bioactive-glass-ceramic-cage-in-single-level-acdf-versus-peek-cage-filled-with-autologous-bone
#37
JOURNAL ARTICLE
Ji-Won Kwon, Yong Ho Lee, Byung Ho Lee, Jae Hong Kim, Kyung Soo Suk
Bioactive glass-ceramic (BGC) cage is a substitute for polyether ether ketone (PEEK) cages in anterior cervical discectomy and fusion (ACDF). Only a few comparative studies exist using PEEK and non-window-type BGC cages (CaO-SiO2 -P2 O5 -B2 O3 ) in single-level ACDF. This study compared PEEK cages filled with autologous iliac bone grafts and BGC cages regarding clinical safety and effectiveness. A retrospective case series was performed on 40 patients who underwent single-level ACDF between October 2020 and July 2021 by a single orthopedic spine surgeon...
February 19, 2024: Scientific Reports
https://read.qxmd.com/read/38355361/automatic-assessment-of-ultrasound-curvature-angle-for-scoliosis-detection-using-3-d-ultrasound-volume-projection-imaging
#38
JOURNAL ARTICLE
Sunetra Banerjee, Zixun Huang, Juan Lyu, Frank H F Leung, Timothy Lee, De Yang, Yongping Zheng, Jeb McAviney, Sai Ho Ling
OBJECTIVE: Scoliosis is a spinal deformation in which the spine takes a lateral curvature, generating an angle in the coronal plane. The conventional method for detecting scoliosis is measurement of the Cobb angle in spine images obtained by anterior X-ray scanning. Ultrasound imaging of the spine is found to be less ionising than traditional radiographic modalities. For posterior ultrasound scanning, alternate indices of the spinous process angle (SPA) and ultrasound curve angle (UCA) were developed and have proven comparable to those of the traditional Cobb angle...
February 13, 2024: Ultrasound in Medicine & Biology
https://read.qxmd.com/read/38347518/finite-element-biomechanical-analysis-of-3d-printed-intervertebral-fusion-cage-in-osteoporotic-population
#39
JOURNAL ARTICLE
Jincheng Wu, Jun Miao, Guangdong Chen, Hanpeng Xu, Wangqiang Wen, Haoxiang Xu, Lizhu Liu
OBJECTIVE: To study the biomechanical characteristics of each tissue structure when using different 3D printing Cage in osteoporotic patients undergoing interbody fusion. METHODS: A finite element model of the lumbar spine was reconstructed and validated with regarding a range of motion and intervertebral disc pressure from previous in vitro studies. Cage and pedicle screws were implanted and part of the lamina, spinous process, and facet joints were removed in the L4/5 segment of the validated mode to simulate interbody fusion...
February 12, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38310767/predicting-cervico-thoraco-lumbar-vertebra-positions-from-cutaneous-markers-combining-local-frame-and-postural-predictors-improves-robustness-to-posture
#40
JOURNAL ARTICLE
A Tomezzoli, A Agouram, B Chalamet, J-B Pialat, S Duprey, V Cunin, B Fréchède
Predictions of vertebra positions from external data are required in many fields like motion analysis or for clinical applications. Existing predictions mainly cover the thoraco-lumbar spine, in one posture. The objective of this study was to develop a method offering robust vertebra position predictions in different postures for the whole spine, in the sagittal plane. EOS radiographs were taken in three postures: slouched, erect, and subject's usual sitting posture, using 21 healthy participants pre-equipped with opaque cutaneous markers...
February 1, 2024: Journal of Biomechanics
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