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https://www.readbyqxmd.com/read/29774196/common-carotid-artery-dissection-in-multiple-extracranial-injury-a-case-report
#1
Jin Sang Kil, Mi Kyung Lee, Ki Seong Eom
Traumatic common carotid artery dissection (CCAD) is rare. To our knowledge, only 14 case reports have described traumatic CCAD previously. Here, we report a case of CCAD in a patient with severe trauma. A 50-year-old man was lying on the road after drinking alcohol when a car drove over him. Computed tomography (CT) revealed multiple rib fractures with hemopneumothorax, lung contusion, flail chest, large amount of hematoma with bladder rupture, and fractures on the C6 spinous process, sacral ala, iliac bone, and pubic ramus...
April 2018: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29761492/c7-vertebra-homeotic-transformation-in-domestic-dogs-are-pug-dogs-breaking-mammalian-evolutionary-constraints
#2
J Brocal, S De Decker, R José-López, E G Manzanilla, J Penderis, C Stalin, S Bertram, J J Schoenebeck, C Rusbridge, N Fitzpatrick, R Gutierrez-Quintana
The number of cervical vertebrae in mammals is almost constant at seven, regardless of their neck length, implying that there is selection against variation in this number. Homebox (Hox) genes are involved in this evolutionary mammalian conservation, and homeotic transformation of cervical into thoracic vertebrae (cervical ribs) is a common phenotypic abnormality when Hox gene expression is altered. This relatively benign phenotypic change can be associated with fatal traits in humans. Mutations in genes upstream of Hox, inbreeding and stressors during organogenesis can also cause cervical ribs...
May 14, 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/29750048/genitogluteal-porokeratosis-a-clinical-review
#3
REVIEW
Rajiv Joshi, Khushboo Minni
Porokeratosis is an uncommon disorder of keratinization that presents with keratotic papules or annular plaques that expand centrifugally with a thread-like elevated border. A distinctive histologic structure, the cornoid lamella, is diagnostic of this disorder and consists of a column of parakeratosis with the absence of the granular layer and dyskeratotic cells in the upper spinous zone. Porokeratosis confined to the genitogluteal region is rare and may be subclassified into three types, namely, classical porokeratosis on the genital region, ptychotropic porokeratosis most often seen in the natal cleft and buttocks and penoscrotal porokeratosis that is seen on the penis and adjacent scrotal skin in young men in their third decade of life...
2018: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/29749801/treatment-of-atlantoaxial-dislocations-among-patients-with-cervical-osseous-or-vascular-abnormalities-utilizing-hybrid-techniques
#4
Shenglin Wang, Yinglun Tian, Bassel G Diebo, Samantha R Horn, Peter G Passias
OBJECTIVE Most cervical fixations for atlantoaxial dislocation (AAD) are bilateral and symmetric; however, in the setting of osseous and vascular deformity at the craniovertebral junction, asymmetrical and hybrid fixations are used as "salvage" techniques. Because of the rarity of these cases, hybrid cervical fixations for AAD have not been fully explored. The aim of this study was to evaluate the clinical feasibility and outcomes of posterior hybrid cervical fixations for AAD. METHODS Twenty-one AAD cases were retrospectively studied; 18 had cervical myelopathy with Japanese Orthopaedic Association (JOA) scores ranging from 9 to 16 (mean 13...
May 11, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29738605/keratin-4-regulates-the-development-of-human-white-sponge-nevus
#5
Jianming Zhang, Jingjing Quan, Yongyuan Ren, Mengshan Chen, Jie Yang, Xu Zhang
BACKGROUND: The aim of this study was to investigate the roles of keratin 4 (KRT4) gene in the development of human white sponge nevus (WSN). METHODS: Transgenic mice were created using the microinjection method with pcDNA3.1 vectors expressing KRT4 wild-type (WT) gene and E520K mutation. Polymerase chain reaction (PCR) and western blotting were used to identify the genotype of transgenic founders and their filial generations. Expression of KRT4 in mouse oral mucosa was characterized by immunohistochemistry (IHC), and the whole epithelium layer of transgenic mice was observed by using transmission electron microscope (TEM)...
May 8, 2018: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29730469/normal-microscopic-anatomy-of-equine-body-and-limb-skin-a-morphological-and-immunohistochemical-study
#6
Elin Jørgensen, Giulia Lazzarini, Andrea Pirone, Stine Jacobsen, Vincenzo Miragliotta
INTRODUCTION: Information on microscopic anatomy of equine skin is sparse. In horses, limb wounds often become chronic and/or non-healing whereas body wounds heal normally. These dissimilarities in healing patterns might be a product of different phenotypic characteristics of body and limb skin. The objective of this study was to investigate microscopic anatomy, epidermal thickness, keratinocyte proliferation and differentiation as well as the presence of mast cells in normal equine skin of body and limb...
May 3, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29730457/anterior-posterior-length-discrepancy-of-the-spinal-column-in-adolescent-idiopathic-scoliosis-a-3d-ct-study
#7
Rob C Brink, Tom P C Schlösser, Marijn van Stralen, Koen L Vincken, Moyo C Kruyt, Steve C N Hui, Max A Viergever, Winnie C W Chu, Jack C Y Cheng, René M Castelein
BACKGROUND CONTEXT: One of the characteristics of reported observations in adolescent idiopathic scoliosis (AIS) is that the thoracic spine is longer anteriorly than posteriorly, more pronounced around the apex than the transitional zones. This reversal of the normal kyphotic anatomy of the thoracic spine is related to questions of etiopathogenesis of AIS. The changes in the anatomy of the anterior column have been described rather in detail, however, the role of the posterior spinal column and the laminae has so far not been elucidated...
May 3, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29713399/chitosan-pad-cellulose-membrane-or-gelatin-sponge-for-peridural-bleeding-an-efficacy-study-on-a-lumbar-laminectomized-rat-model
#8
Surachai Sae-Jung, Punyawat Apiwatanakul
Study Design: Experimental study in an animal model. Purpose: This study aims to evaluate the hemostatic properties of four common hemostatic materials including the chitosan clot pad, absorbable gelatin sponge, cellulose membrane, and gauze on peridural bleeding using a rat model. Overview of Literature: Intraoperative bleeding during spinal surgery can lead to morbidities. Hemostatic materials have been developed, but the efficacy of these materials on peridural bleeding remains unclear...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29709549/use-of-the-subcutaneous-lumbar-spine-sls-index-as-a-predictor-for-surgical-complications-in-lumbar-spine-surgery
#9
Kylie Shaw, James Chen, William Sheppard, Mohanad Alazzeh, Howard Park, Don Park, A Nick Shamie
BACKGROUND CONTEXT: Lumbar spine surgeries require adequate exposure to visualize key structures and limited exposure can make surgery more technically difficult, thus increasing the potential for complications. Body mass index and body mass distribution have been shown to be associated with worse surgical outcomes. PURPOSE: This study aims to further previous investigations in elucidating the predictive nature of body mass distribution with peri- and post-operative complications in lumbar surgery...
April 27, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29708263/parameters-and-functional-analysis-of-the-deep-epaxial-muscles-in-the-thoracic-lumbar-and-sacral-regions-of-the-equine-spine
#10
J A García Liñeiro, G H Graziotti, J M Rodríguez Menéndez, C M Ríos, N O Affricano, C L Victorica
The epaxial muscles produce intervertebral rotation in the transverse, vertical and axial axes. These muscles also counteract the movements induced by gravitational and inertial forces and movements produced by antagonistic muscles and the intrinsic muscles of the pelvic limb. Their fascicles are innervated by the dorsal branch of the spinal nerve, which corresponds to the metamere of its cranial insertion in the spinous process. The structure allows the function of the muscles to be predicted: those with long and parallel fibres have a shortening function, whereas the muscles with short and oblique fibres have an antigravity action...
April 30, 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/29702415/robust-variational-segmentation-of-3d-bone-ct-data-with-thin-cartilage-interfaces
#11
Tarun Gangwar, Jeff Calder, Takashi Takahashi, Joan E Bechtold, Dominik Schillinger
We present a two-stage variational approach for segmenting 3D bone CT data that performs robustly with respect to thin cartilage interfaces. In the first stage, we minimize a flux-augmented Chan-Vese model that accurately segments well-separated regions. In the second stage, we apply a new phase-field fracture inspired model that reliably eliminates spurious bridges across thin cartilage interfaces, resulting in an accurate segmentation topology, from which each bone object can be identified. Its mathematical formulation is based on the phase-field approach to variational fracture, which naturally blends with the variational approach to segmentation...
April 17, 2018: Medical Image Analysis
https://www.readbyqxmd.com/read/29690405/a-new-species-of-buenia-perciformes-gobiidae-from-the-western-mediterranean-slope-bottoms-the-redescription-of-buenia-jeffreysi-and-the-first-balearic-record-of-buenia-affinis
#12
Marcelo KovaČiĆ, Francesc Ordines, Ulrich K Schliewen
A new gobiid species, Buenia lombartei sp. nov. (Teleostei: Gobiidae) is described from the continental slope off the Balearic Islands, western Mediterranean. The Atlantic species Buenia jeffreysii (Günther, 1867) is redescribed and the first record of Buenia affinis Iljin, 1930 is reported for the islands. A key for the species of genus Buenia is provided. The new species can be distinguished from congeneric species by morphological characters: anterior oculoscapular canal semi-closed with pores σ, λ, κ, α, ρ and additional pores and open furrows; suborbital row c of 6 papillae; anal fin I/7-I/8; scales in lateral series 25-27; scales in transverse series 6; pectoral fin rays 18; the second spine of the first dorsal fin longest, backwards reaching to middle second dorsal fin in males when folded down; pelvic fin anterior membrane reduced to less than one sixth of spinous ray in midline depth; tongue well developed and bilobed and several morphometric characters...
March 8, 2018: Zootaxa
https://www.readbyqxmd.com/read/29688555/a-pilot-study-on-posterior-polyethylene-tethers-to-prevent-proximal-junctional-kyphosis-after-multilevel-spinal-instrumentation-for-adult-spinal-deformity
#13
Thomas J Buell, Avery L Buchholz, John C Quinn, Shay Bess, Breton G Line, Christopher P Ames, Frank J Schwab, Virginie Lafage, Christopher I Shaffrey, Justin S Smith
BACKGROUND: Proximal junctional kyphosis (PJK) is a common problem after multilevel spine instrumentation. OBJECTIVE: To determine if junctional tethers reduce PJK after multilevel instrumented surgery for adult spinal deformity (ASD). METHODS: ASD patients who underwent posterior instrumented fusion were divided into 3 groups: no tether (NT), polyethylene tether-only (TO; tied securely through the spinous processes of the uppermost instrumented vertebra [UIV] + 1 and UIV-1), and tether with crosslink (TC; passed through the spinous process of UIV+1 and tied to a crosslink between UIV-1 and UIV-2)...
April 24, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29675328/smartphone-confocal-microscopy-for-imaging-cellular-structures-in-human-skin-in-vivo
#14
Esther E Freeman, Aggrey Semeere, Hany Osman, Gary Peterson, Milind Rajadhyaksha, Salvador González, Jeffery N Martin, R Rox Anderson, Guillermo J Tearney, Dongkyun Kang
We report development of a low-cost smartphone confocal microscope and its first demonstration of in vivo human skin imaging. The smartphone confocal microscope uses a slit aperture and diffraction grating to conduct two-dimensional confocal imaging without using any beam scanning devices. Lateral and axial resolutions of the smartphone confocal microscope were measured as 2 and 5 µm, respectively. In vivo confocal images of human skin revealed characteristic cellular structures, including spinous and basal keratinocytes and papillary dermis...
April 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29673822/vascularized-spinous-process-graft-rotated-on-a-paraspinous-muscle-pedicle-for-lumbar-fusion-technique-description-and-early-clinical-experience
#15
Michael A Bohl, Kaith K Almefty, Mark C Preul, Jay D Turner, U Kumar Kakarla, Edward M Reece, Steve W Chang
BACKGROUND: Vascularized bone grafts (VBGs) are described as having superior osteogenicity, osteoconductivity, and osteoinductivity compared with other graft types, and have been used in high-risk patients to augment arthrodesis. Pedicled VBGs are rotated on an intact vascular pedicle and therefore maintain all the benefits of VBG, but avoid many of the challenges and additional morbidity of free-tissue transfer. This study describes a novel surgical technique for rotating vascularized spinous process into the posterolateral space for augmenting arthrodesis in patients undergoing posterolateral fusion (PLF)...
April 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29672635/differential-transmission-of-the-molecular-signature-of-rbsp3-limd1-and-cdc25a-in-basal-parabasal-versus-spinous-of-normal-epithelium-during-head-and-neck-tumorigenesis-a-mechanistic-study
#16
Shreya Sarkar, Neyaz Alam, Syam Sundar Mandal, Kabita Chatterjee, Supratim Ghosh, Susanta Roychoudhury, Chinmay Kumar Panda
Head and neck squamous cell carcinoma (HNSCC) is a global disease and mortality burden, necessitating the elucidation of its molecular progression for effective disease management. The study aims to understand the molecular profile of three candidate cell cycle regulatory genes, RBSP3, LIMD1 and CDC25A in the basal/ parabasal versus spinous layer of normal oral epithelium and during head and neck tumorigenesis. Immunohistochemical expression and promoter methylation was used to determine the molecular signature in normal oral epithelium...
2018: PloS One
https://www.readbyqxmd.com/read/29668444/oblong-sesamoid-bone-appearance-into-the-nuchal-ligament-a-case-report
#17
Themistoklis Tzatzairis, Jannis V Papathanasiou, Athanasios Ververidis, Ioannis Kazakos, Georgios Drosos, Konstantinos Tilkeridis
Radio-opaque formations behind the spinous processes of the cervical spine are really rare. They were described in 1929 for the first time. Sesamoid ossicles are found close to a bone or a joint and are usually small. Some sesamoids form part of normal human anatomy, while others are normal anatomical variants. We report a case of a 73-year-old Caucasian male who visited the outpatient clinic complaining about chronic cervical pain. An oblong sesamoid accidentally discovered during routine anteroposterior (AP) and lateral x-ray, within the nuchal ligament (NL) at the C3-C6 spinous processes level...
March 1, 2018: Folia Medica
https://www.readbyqxmd.com/read/29643538/-anterior-cervical-discectomy-and-fusion-to-treat-cervical-spondylosis-with-sympathetic-symptoms
#18
H Liu, L Yue, S L Chen, B Hu, C D Li, X D Yi, H Li, H L Lu, Y Wang, Z R Yu, H L Sun, S J Wang, Y Zhao, L T Qi, R Wang
OBJECTIVE: To investigate the clinical effectiveness of polytheretherketone (PEEK) cages assisted anterior cervical discetomy and fusion (ACDF) to treat cervical spondylosis with sympathetic symptoms. METHODS: Retrospective analysis was undertaken for 39 patients who were diagnosed as cervical spondylosis with sympathetic symptoms and underwent ACDF with PEEK cages. Radiographs obtained before surgery, after surgery, and at the final follow-up were assessed for quality of fusion...
April 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/29628805/accuracy-of-motion-palpation-flexion-extension-test-in-identifying-the-seventh-cervical-spinal-process
#19
Luciana C Póvoa, Ana P A Ferreira, José F C Zanier, Julio G Silva
Objective: The aim of this study was to evaluate the accuracy of a motion palpation procedure, the flexion-extension test, in localizing the spinous process of the seventh cervical vertebra (C7). Methods: We analyzed 101 adult participants with metal markers that permitted the identification of the C7 spinous process. This analysis occurred during a flexion-extension test and was confirmed by radiography. Data sample characteristics were analyzed by descriptive statistics, and the relationship between independent variables (weight, height, sex, age, and body mass index [BMI]) and dependent variables (coincidence between the most prominent vertebra and the stationary vertebra, as determined by the flexion-extension test) was determined via logistic regression...
March 2018: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29621904/the-birth-canal-correlation-between-the-pubic-arch-angle-the-interspinous-diameter-and-the-obstetrical-conjugate-a-computed-tomography-biometric-study-in-reproductive-age-women
#20
Sharon Perlman, Lisa Raviv-Zilka, Denis Levinsky, Ayelet Gidron, Reuven Achiron, Yinon Gilboa, Zvi Kivilevitch
BACKGROUND: Assessment of pelvic configuration is an important factor in the prediction of a successful vaginal birth. However, manual evaluation of the pelvis is practically a vanishing art, and imaging techniques are not available as a real time bed side tool. Unlike the obstetrical conjugate diameter (OC) and inter spinous diameter (ISD), the pubic arch angle (PAA) can be easily measured by transperineal ultrasound. OBJECTIVES: Three dimensional computed tomography bone reconstructions were used to measure the three main birth canal diameters, evaluate the correlation between them and establish the normal reference range for the inlet, mid- and pelvic outlet...
April 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
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