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https://www.readbyqxmd.com/read/29446079/dietary-intake-of-nutrients-involved-in-one-carbon-metabolism-and-risk-of-urothelial-cell-carcinoma-a-prospective-cohort-study
#1
Pierre-Antoine Dugué, Maree T Brinkman, Allison M Hodge, Julie K Bassett, Damien Bolton, Anthony Longano, John L Hopper, Melissa C Southey, Dallas R English, Roger L Milne, Graham G Giles
Nutrients involved in one-carbon metabolism may play a role in carcinogenesis through DNA replication, repair and methylation mechanisms. Most studies on urothelial cell carcinoma (UCC) have focused on folate. We sought to examine the association between B-group vitamins and methionine intake and UCC risk, overall and by subtype, and to test whether these associations are different for population subgroups whose nutritional status may be compromised. We followed participants in the Melbourne Collaborative Cohort Study (N=41,513) for over 20 years, and observed 500 UCC cases (89% originating in the bladder; superficial: 279, invasive: 221)...
February 15, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29416583/assessment-of-serum-vitamin-b12-levels-and-other-metabolic-parameters-in-subjects-with-different-values-of-bone-mineral-density
#2
Marianna Renis, Debora Lobreglio, Pierpaolo Congedo, Maria Concetta Montinaro, Maurizio Muratore, Giambattista Lobreglio
Background: Controversial experimental and clinical evidences have raised questions regarding the role of B12 and insulin-like growth factor 1 (IGF-1) on osteoblast function and bone health. In this study, we aimed to determine if the serum levels of B12, IGF-1 and procollagen type 1 N-terminal propeptide (P1NP) are associated with different degrees of bone mineral density (BMD). Methods: A total of 287 subjects (190 women and 97 men; mean age 53 years) volunteered for evaluation of BMD and serum levels of B12, IGF-1 and P1NP; BMD at lumbar spine and proximal femur was evaluated by means of dual-energy X-ray absorption (DEXA) and expressed as T-score; serum concentrations of vitamin B12 and IGF1 were measured with a chemiluminescent immunoassay on Access II Beckman Coulter and DiaSorin Liaison XL analyzers, respectively; P1NP was assessed in 61 women and 35 men with reduced T-score on Roche Modular platform...
March 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29415843/association-between-nutrient-patterns-and-bone-mineral-density-among-ageing-adults
#3
Yohannes Adama Melaku, Tiffany K Gill, Anne W Taylor, Robert Adams, Zumin Shi
BACKGROUND AND AIM: There is limited evidence on the link between the overall nutrients intake from diet and bone mineral density (BMD). We assessed the association between nutrient patterns and BMD among an ageing Australian population. METHODS: Participants (n = 1135; males, 45.8%; median age, 62.0 years) with dietary and BMD data in the North West Adelaide Health Study (NWAHS) were included. Dietary intake was assessed using a food frequency questionnaire. BMD was measured using dual-energy X-ray absorptiometry...
December 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29370378/soft-x-ray-emission-spectroscopy-study-of-electronic-structure-of-sodium-borosilicide-na8b74-5si17-5
#4
Masami Terauchi, Haruhiko Morito, Hisanori Yamane, Shogo Koshiya, Koji Kimoto
Chemical bonding state of sodium borosilicide Na8B74.5Si17.5, which is a new member of B12-cluster materials, is investigated by soft X-ray emission spectroscopy. The material is composed of B12 cluster network and characteristic silicon chains of [-Si-(Si-Si)3-Si-] connected by sp3 bonding, in which bonding distances and bonding angles are close to those in cubic Si crystal. B K-emission spectrum of the material showed a similar but a broader intensity distribution with those of B12 cluster materials of α-r-B, B4C and β-r-B...
January 23, 2018: Microscopy
https://www.readbyqxmd.com/read/29361684/micronutrient-gaps-in-three-commercial-weight-loss-diet-plans
#5
Matthew G Engel, Hua J Kern, J Thomas Brenna, Susan H Mitmesser
Weight-loss diets restrict intakes of energy and macronutrients but overlook micronutrient profiles. Commercial diet plans may provide insufficient micronutrients. We analyzed nutrient profiles of three plans and compared their micronutrient sufficiency to Dietary Reference Intakes (DRIs) for male U.S. adults. Hypocaloric vegan (Eat to Live-Vegan, Aggressive Weight Loss; ETL-VAWL), high-animal-protein low-carbohydrate (Fast Metabolism Diet; FMD) and weight maintenance (Eat, Drink and Be Healthy; EDH) diets were evaluated...
January 20, 2018: Nutrients
https://www.readbyqxmd.com/read/29355097/usual-nutrient-intake-adequacy-among-young-rural-zambian-children
#6
Bess L Caswell, Sameera A Talegawkar, Ward Siamusantu, Keith P West, Amanda C Palmer
Inadequate nutrient intakes put children at risk for impaired growth and development. We described diet, usual intakes of energy and macro- and micronutrients and prevalence of nutrient intake adequacies among 4-8-year-old Zambian children. Children not yet in school and living in Mkushi District, Central Province, Zambia were enrolled into an efficacy trial of pro-vitamin A biofortified maize. Children in the non-intervened arm were included in this analysis (n 202). Dietary intake data were collected by tablet-based 24-h recall on a monthly basis over the 6-month trial...
January 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29338257/a-dynamic-protein-protein-coupling-between-the-tonb-dependent-transporter-fhua-and-tonb
#7
Jessica L Sarver, Michael Zhang, Lishan Liu, David Nyenhuis, David S Cafiso
Bacterial outer membrane TonB-dependent transporters function by executing cycles of binding and unbinding to the inner membrane protein TonB. In the vitamin B12 transporter BtuB and the ferric citrate transporter FecA, substrate binding increases the periplasmic exposure of the Ton box, an energy-coupling segment. This increased exposure appears to enhance the affinity of the transporter for TonB. Here, continuous wave and pulse EPR spectroscopy were used to examine the state of the Ton box in the Escherichia coli ferrichrome transporter FhuA...
January 26, 2018: Biochemistry
https://www.readbyqxmd.com/read/29331158/dietary-sources-of-energy-and-nutrients-in-the-contemporary-diet-of-inuit-adults-results-from-the-2007-08-inuit-health-survey
#8
Tiff-Annie Kenny, Xue Feng Hu, Harriet V Kuhnlein, Sonia D Wesche, Hing Man Chan
OBJECTIVE: To characterize the major components of the contemporary Inuit diet and identify the primary sources of energy and essential nutrients. DESIGN: Dietary data were derived from the 24 h recall collected by the Inuit Health Survey (IHS) from 2007 to 2008. The population proportion method was used to determine the percentage contribution of each group. Unique food items/preparations (ninety-three country foods and 1591 market foods) were classified into eight country food groups and forty-one market food groups...
January 14, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29300423/effects-of-low-dose-dairy-protein-plus-micronutrient-supplementation-during-resistance-exercise-on-muscle-mass-and-physical-performance-in-older-adults-a-randomized-controlled-trial
#9
S Seino, K Sumi, M Narita, Y Yokoyama, K Ashida, A Kitamura, S Shinkai
OBJECTIVES: To investigate whether supplementation with low-dose dairy protein plus micronutrients augments the effects of resistance exercise (RE) on muscle mass and physical performance compared with RE alone among older adults. DESIGN: Randomized controlled trial. SETTING: Tokyo, Japan. PARTICIPANTS: Eighty-two community-dwelling older adults (mean age, 73.5 years) were randomly allocated to an RE plus dairy protein and micronutrient supplementation group or an RE only group (n = 41 each)...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29290452/short-communication-effects-of-dietary-5-6-dimethylbenzimidazole-supplementation-on-vitamin-b12-supply-lactation-performance-and-energy-balance-in-dairy-cows-during-the-transition-period-and-early-lactation
#10
D M Wang, B X Zhang, J K Wang, H Y Liu, J X Liu
The current study was conducted to investigate the effects of 5,6-dimethylbenzimidazole (DMB) supplementation to the feed during the transition period and early lactation on the vitamin B12 supply, lactation performance, and energy balance in postpartum cows. Twenty-four prepartum Holstein dairy cows were divided into 12 blocks based on their parity and milk yield at the last lactation and were then randomly allocated to 1 of 2 treatments: a basal diet without DMB (control) or a treatment diet that contained 1...
December 28, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29283566/interaction-mode-and-regioselectivity-in-vitamin-b12-dependent-dehalogenation-of-aryl-halides-by-dehalococcoides-mccartyi-strain-cbdb1
#11
Shangwei Zhang, Lorenz Adrian, Gerrit Schüürmann
The bacterium Dehalococcoides, strain CBDB1, transforms aromatic halides through reductive dehalogenation. So far, however, the structures of its vitamin B12-containing dehalogenases are unknown, hampering clarification of the catalytic mechanism and substrate specificity as basis for targeted remediation strategies. This study employs a quantum chemical donor-acceptor approach for the Co(I)-substrate electron transfer. Computational characterization of the substrate electron affinity at carbon-halogen bonds enables discriminating aromatic halides ready for dehalogenation by strain CBDB1 (active substrates) from non-dehalogenated (inactive) counterparts with 92% accuracy, covering 86 of 93 bromobenzenes, chlorobenzenes, chlorophenols, chloroanilines, polychlorinated biphenyls, and dibenzo-p-dioxins...
December 28, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29244867/dietary-sources-and-intakes-of-folates-and-vitamin-b12-in-the-spanish-population-findings-from-the-anibes-study
#12
Teresa Partearroyo, María de Lourdes Samaniego-Vaesken, Emma Ruiz, Josune Olza, Javier Aranceta-Bartrina, Ángel Gil, Marcela González-Gross, Rosa M Ortega, Lluis Serra-Majem, Gregorio Varela-Moreiras
BACKGROUND: Folates and vitamin B12 are key nutrients in one-carbon metabolism and related diseases. Updated and plausible information on population intakes and their major dietary sources is scarce and urgently needed in Spain in order to increase the knowledge that can lead as previous step to prevention by fortification and supplementation policies. AIMS: The present study aims to evaluate main dietary folate and vitamin B12 sources and intakes in the Spanish population...
2017: PloS One
https://www.readbyqxmd.com/read/29227653/structural-stability-and-evolution-of-medium-sized-tantalum-doped-boron-clusters-a-half-sandwich-structured-tab12-cluster
#13
Bo Le Chen, Wei Guo Sun, Xiao Yu Kuang, Cheng Lu, Xin Xin Xia, Hong Xiao Shi, George Maroulis
Transition-metal (TM)-doped boron clusters have received considerable attention in recent years, in part, because of their remarkable size-dependent structural and electronic properties. However, the structures of medium-sized boron clusters doped with TM atoms are still not well-known because of the much increased complexity of the potential surface as well as the rapid increase in the number of low-energy isomers, which are the challenges in cluster structural searches. Here, by means of an unbiased structure search, we systematically investigated the structural evolution of medium-sized tantalum-doped boron clusters, TaBn0/- (n = 10-20)...
December 11, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/29130712/-development-of-a-food-composition-database-for-valoration-of-dietary-intake-in-peruvian-amazon
#14
María García Rodríguez, Rafael Moreno Rojas, Manuel Romero Saldaña, Guillermo Molina Recio
AIM: The aim of this study was the development of a specific food composition database of Peruvian Amazonia with which value the dietary intake of the population. METHODOLOGY: An observational surveying study has been performed at which 303 individuals aged 3-83 years were selected. To compiling a register of basic food reminders of 24 hours (R24) and frequency foods consumption questionnaires (FFQ) over a four-year period were collected, and were complemented by the National Household Budget Survey...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29125158/photodissociation-of-ethylphenylcobalamin-antivitamin-b12
#15
Piotr Lodowski, Karolina Ciura, Megan J Toda, Maria Jaworska, Pawel M Kozlowski
Biologically active forms of cobalamins are crucial cofactors in biochemical reactions and these metabolites can be inhibited by their structurally similar analogues known as antivitamins B12. Phenylethynylcobalamin (PhEtyCbl) or 4-ethylphenylcobalamin (EtPhCbl) exemplify recently synthesized and structurally characterized antivitamins B12. Herein, DFT and TD-DFT studies of EtPhCbl are provided to explore its photochemical behavior, which may lead to design of arylcobalamins that can be used as therapeutic agents in light activated drug applications...
November 22, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29121493/prevalence-of-consumption-and-nutritional-content-of-breakfast-meal-among-adolescents-from-the-brazilian-national-dietary-survey
#16
Jaqueline L Pereira, Michelle A de Castro, Sinead Hopkins, Carolyn Gugger, Regina M Fisberg, Mauro Fisberg
OBJECTIVE: To estimate the prevalence of breakfast consumption and describe the foods and nutrients consumed at this meal and throughout the day by Brazilian adolescents. METHOD: A total of 7276 adolescents aged 10-19 years were evaluated in the Brazilian National Dietary Survey 2008-9, a population-based cross-sectional study. Individuals' information was collected at home. Dietary data were obtained by two food records. Breakfast was defined as the first eating occasion of the day that occurred between 6 and 9:59am...
November 6, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/29113038/micronutrient-dietary-intake-in-latina-pregnant-adolescents-and-its-association-with-level-of-depression-stress-and-social-support
#17
Angelie Singh, Caroline Trumpff, Jeanine Genkinger, Alida Davis, Marisa Spann, Elizabeth Werner, Catherine Monk
Adolescent pregnant women are at greater risk for nutritional deficits, stress, and depression than their adult counterparts, and these risk factors for adverse pregnancy outcomes are likely interrelated. This study evaluated the prevalence of nutritional deficits in pregnant teenagers and assessed the associations among micronutrient dietary intake, stress, and depression. One hundred and eight pregnant Latina adolescents completed an Automated Self-Administered 24-hour dietary recall (ASA24) in the 2nd trimester...
November 4, 2017: Nutrients
https://www.readbyqxmd.com/read/29109962/micronutrient-intake-in-a-cohort-of-italian-adults-with-type-1-diabetes-adherence-to-dietary-recommendations
#18
Marisa Giorgini, Marilena Vitale, Lutgarda Bozzetto, Ornella Ciano, Angela Giacco, Anna Rivieccio, Ilaria Calabrese, Gabriele Riccardi, Angela A Rivellese, Giovanni Annuzzi
Micronutrients are of fundamental importance in maintaining health status. However, data on their dietary intake are few particularly in persons with diabetes. The aim of this study was to evaluate in adults with type 1 diabetes (T1DM) attending a tertiary-level diabetes center in Southern Italy the intake of micronutrients (both vitamins and minerals) and the adherence to recommendations. Seven-day food records of 60 T1DM patients were analyzed. Micronutrient intake was evaluated based on the Italian food composition tables and expressed as amount per 1000 kcal of energy intake to adjust for possible underreporting...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29034851/nitrosopumilus-maritimus-gen-nov-sp-nov-nitrosopumilus-cobalaminigenes-sp-nov-nitrosopumilus-oxyclinae-sp-nov-and-nitrosopumilus-ureiphilus-sp-nov-four-marine-ammonia-oxidizing-archaea-of-the-phylum-thaumarchaeota
#19
Wei Qin, Katherine R Heal, Rasika Ramdasi, Julia N Kobelt, Willm Martens-Habbena, Anthony D Bertagnolli, Shady A Amin, Christopher B Walker, Hidetoshi Urakawa, Martin Könneke, Allan H Devol, James W Moffett, E Virginia Armbrust, Grant J Jensen, Anitra E Ingalls, David A Stahl
Four mesophilic, neutrophilic, and aerobic marine ammonia-oxidizing archaea, designated strains SCM1(T), HCA1(T), HCE1(T) and PS0(T), were isolated from a tropical marine fish tank, dimly lit deep coastal waters, the lower euphotic zone of coastal waters, and near-surface sediment in the Puget Sound estuary, respectively. Cells are straight or slightly curved small rods, 0.15-0.26 µm in diameter and 0.50-1.59 µm in length. Motility was not observed, although strain PS0(T) possesses genes associated with archaeal flagella and chemotaxis, suggesting it may be motile under some conditions...
October 16, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/29034175/refining-low-protein-modular-feeds-for-children-on-low-protein-tube-feeds-with-organic-acidaemias
#20
A Daly, S Evans, C Ashmore, S Chahal, S Santra, A MacDonald
Children with inherited metabolic disorders (IMD) who are dependent on tube feeding and require a protein restriction are commonly fed by 'modular tube feeds' consisting of several ingredients. A longitudinal, prospective two-phase study, conducted over 18 months assessed the long-term efficacy of a pre-measured protein-free composite feed. This was specifically designed to meet the non-protein nutritional requirements of children (aged over 1 year) with organic acidaemias on low protein enteral feeds and to be used as a supplement with an enteral feeding protein source...
December 2017: Molecular Genetics and Metabolism Reports
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