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Haemofiltration

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https://www.readbyqxmd.com/read/27807020/miliary-tuberculosis-in-an-immunocompetent-male-with-a-fatal-outcome
#1
Louise Dunphy, Elizabeth Keating, T Parke
A man aged 33 years, born in Nepal, but resident in the UK for 7 years presented to the emergency department with a 4-day history of general malaise, fever (temperature 38.6°C) and a non-productive cough. His medical history was unremarkable and no high-risk behaviour was identified. Clinical examination confirmed decreased air entry bilaterally with bibasal crackles. He was tachycardic, with a heart rate of 120 bpm. Further investigation with a 12-lead ECG confirmed supraventricular tachycardia (SVT) which was terminated with vagal manoeuvres...
November 2, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27780589/risk-factors-for-pressure-ulcer-development-in-intensive-care-units-systematic-review
#2
M Lima Serrano, M I González Méndez, F M Carrasco Cebollero, J S Lima Rodríguez
INTRODUCTION: Pressure ulcers represent a significant problem for patients, professionals and health systems. Their reported incidence and prevalence are significant worldwide. Their character iatrogenic states that its appearance is preventable and its incidence is an indicator of scientific and technical quality both in primary care and specialized care. The aim of this review was to identify risk factors associated with the occurrence of pressure ulcers in critically ill patients. METHODOLOGY: The PRISMA Declaration recommendations have been followed and adapted to studies identifying risk factors...
October 22, 2016: Medicina Intensiva
https://www.readbyqxmd.com/read/27709750/concomitant-implantation-of-impella-%C3%A2-on-top-of-veno-arterial-extracorporeal-membrane-oxygenation-may-improve-survival-of-patients-with-cardiogenic-shock
#3
Federico Pappalardo, Christian Schulte, Marina Pieri, Benedikt Schrage, Rachele Contri, Gerold Soeffker, Teresa Greco, Rosalba Lembo, Kai Müllerleile, Antonio Colombo, Karsten Sydow, Michele De Bonis, Florian Wagner, Hermann Reichenspurner, Stefan Blankenberg, Alberto Zangrillo, Dirk Westermann
AIMS: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) support stabilizes patients with cardiogenic shock. Despite improved oxygenation and peripheral circulation, LV unloading may be impeded due to the increased afterload, resulting in a failing static left ventricle and in high mortality. METHODS AND RESULTS: We describe for the first time a large series of patients treated with the combination of VA-ECMO and Impella(®) compared with patients with VA-ECMO only...
October 6, 2016: European Journal of Heart Failure
https://www.readbyqxmd.com/read/27663197/efficacy-and-safety-of-i-v-sodium-benzoate-in-urea-cycle-disorders-a-multicentre-retrospective-study
#4
Marie-Caroline Husson, Manuel Schiff, Alain Fouilhoux, Aline Cano, Dries Dobbelaere, Anais Brassier, Karine Mention, Jean-Baptiste Arnoux, François Feillet, Brigitte Chabrol, Nathalie Guffon, Caroline Elie, Pascale de Lonlay
BACKGROUND: The efficacy and safety of intra-venous (i.v.) sodium benzoate for treating acute episodes of hyperammonemia in urea cycle enzyme disorders (UCD) is well known. However, published data do not provide a clear picture of the benefits and risks of this drug. We report a retrospective multicentre study on the use of i.v. sodium benzoate in patients treated for UCD between 2000 and 2010 in the 6 French reference centres for metabolic diseases. RESULTS: Sixty-one patients with UCDs - 22 ornithine transcarbamylase (20 confirmed, 2 suspected), 18 arginino-succinate synthetase, 15 carbamoyl phosphate synthetase, 3 arginosuccinate lyase, 1 arginase deficiency, 1 N-acetylglutamate synthetase, 1 HHH syndrome - required i...
September 23, 2016: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/27659871/development-and-application-of-novelty-pretreatment-method-for-the-concurrent-quantitation-of-eleven-water-soluble-b-vitamins-in-ultrafiltrates-after-renal-replacement-therapy
#5
Dorota Wirkus, Aleksandra Jakubus, Radosław Owczuk, Piotr Stepnowski, Monika Paszkiewicz
Continous renal replacement therapy (CRRT) is particularly recommended for septic shock patients in intensive care units. The CRRT technique used most frequently is high volume continuous veno-venous haemofiltration. It provides a high rate of clearance of uremic toxins and inflammatory cytokines. However, it should also be taken into account that substances important for homeostasis may be concurrently unintentionally removed. Accordingly, water-soluble vitamins can be removed during continuous renal replacement therapy, and the estimate of the loss is critical to ensure appropriate supplementation...
September 15, 2016: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/27461439/polonium-210-poisoning-a-first-hand-account
#6
Amit C Nathwani, James F Down, John Goldstone, James Yassin, Paul I Dargan, Andres Virchis, Nick Gent, David Lloyd, John D Harrison
BACKGROUND: Polonium-210 ((210)Po) gained widespread notoriety after the poisoning and subsequent death of Mr Alexander Litvinenko in London, UK, in 2006. Exposure to (210)Po resulted initially in a clinical course that was indistinguishable from infection or exposure to chemical toxins, such as thallium. METHODS: A 43-year-old man presented to his local hospital with acute abdominal pain, diarrhoea, and vomiting, and was admitted to the hospital because of dehydration and persistent gastrointestinal symptoms...
September 10, 2016: Lancet
https://www.readbyqxmd.com/read/27358096/thermal-dysregulation-in-prader-willi-syndrome-a-potentially-fatal-complication-in-adolescence-not-just-in-infancy
#7
Steven McVea, Andrew James Thompson, Noina Abid, Julie Richardson
A 13-year-old boy with a background of Prader-Willi syndrome (PWS) was admitted to the regional paediatric intensive care unit, with community-acquired pneumonia. Despite a week of intravenous antibiotics, resolution of inflammatory markers and resolving consolidation on radiograph, he remained feverish. Fever of unknown origin investigations were negative and he was diagnosed with central thermal dysregulation secondary to hypothalamic dysfunction in PWS. Following a hyperpyrexia period, secondary rhabdomyolysis and renal failure developed...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27338750/a-retrospective-review-of-fluid-balance-control-in-crrt
#8
Hugh Davies, Gavin D Leslie, David Morgan
INTRODUCTION: An effect of severe acute kidney injury (AKI) is the development of oliguria and subsequent retention of fluid. Recent studies have reported an association between fluid overload and increased mortality in critically ill patients. Achieving fluid balance control through haemofiltration is an important part of dialysis dose delivery in continuous renal replacement therapy (CRRT). AIMS: (1) Compare the prescribed dose with the delivered dose of dialysis and haemofiltration for CRRT...
June 20, 2016: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/27290201/linezolid-pharmacokinetics-in-critically-ill-patients-with-renal-replacement-therapy-comparison-of-equi-dose-of-continuous-veno-venous-haemofiltration-with-continuous-veno-venous-haemodiafiltration
#9
C Roger, B Louart, L Muller, J A Roberts, J Y Lefrant
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27289967/the-improve-immune-function-of-haemofiltration-combine-with-ha-haemoadsorption-in-hla-dr-low-expression-of-sepsis-patients
#10
L Ying
No abstract text is available yet for this article.
December 2015: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/27176622/regional-citrate-versus-heparin-anticoagulation-for-continuous-renal-replacement-therapy-in-critically-ill-patients-a-meta-analysis-with-trial-sequential-analysis-of-randomized-controlled-trials
#11
Chao Liu, Zhi Mao, Hongjun Kang, Jie Hu, Feihu Zhou
BACKGROUND: Regional citrate or heparin is often prescribed as an anticoagulant for continuous renal replacement therapy (CRRT). However, their efficacy and safety remain controversial. Therefore, we performed this meta-analysis to compare these two agents and to determine whether the currently available evidence is sufficient and conclusive by using trial sequential analysis (TSA). METHODS: We searched for relevant studies in PubMed, Embase, the Cochrane Library databases and the China National Knowledge Infrastructure (CNKI) Database from database inception until September 2015...
May 13, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27030462/bilateral-ureteric-stones-an-unusual-cause-of-acute-kidney-injury
#12
Daniel Sumner, Lucas Rehnberg, Aaron Kler
A 49-year-old man presented to the accident and emergency department, with a short history of vague abdominal pain, abdominal distension and two episodes of frank haematuria. A plain chest film showed dilated loops of large bowel and blood results on admission showed an acute kidney injury (stage 3). A diagnosis of bowel obstruction was made initially but a CT scan of the abdomen showed bilateral obstructing calculi. After initial resuscitation, the patient had bilateral ultrasound-guided nephrostomies and haemofiltration...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/26957490/comparison-of-equal-doses-of-continuous-venovenous-haemofiltration-and-haemodiafiltration-on-ciprofloxacin-population-pharmacokinetics-in-critically-ill-patients
#13
Claire Roger, Steven C Wallis, Benjamin Louart, Jean-Yves Lefrant, Jeffrey Lipman, Laurent Muller, Jason A Roberts
OBJECTIVES: Whilst commonly performed in ICUs, renal replacement therapies (RRTs) differ in their solute clearances. There is a paucity of data on ciprofloxacin clearances in different RRT techniques. The aim of this study was to compare the population pharmacokinetics of ciprofloxacin during equal doses of continuous venovenous haemofiltration (CVVHF) and continuous venovenous haemodiafiltration (CVVHDF) in septic patients. METHODS: Patients receiving 400 mg of ciprofloxacin intravenously 8 or 12 hourly and undergoing either CVVHF or CVVHDF were eligible...
June 2016: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/26921882/haemodiafiltration-haemofiltration-and-haemodialysis-for-end-stage-kidney-disease
#14
Angela Webster, Ionut Nistor
No abstract text is available yet for this article.
June 2016: Nephrology
https://www.readbyqxmd.com/read/26911799/the-effect-of-pulsatile-cardiopulmonary-bypass-on-the-need-for-haemofiltration-in-patients-with-renal-dysfunction-undergoing-cardiac-surgery
#15
Shakil Farid, Hannah Povey, Simon Anderson, Samer A M Nashef, Yasir Abu-Omar
OBJECTIVES: The aim of our study was to investigate the effects of pulsatile cardiopulmonary bypass (CPB) on renal function and the need for haemofiltration in patients with preoperative renal impairment undergoing cardiac surgery. METHODS: Clinical data were collected prospectively for patients undergoing cardiac surgery with pulsatile CPB (Group A, n=66) and compared to matched patients with standard non-pulsatile CPB (Group B, n=66). Patients included in the study had mild renal impairment and at least moderate risk from surgery as defined by logistic EuroSCORE...
September 2016: Perfusion
https://www.readbyqxmd.com/read/26879802/continuous-flow-peritoneal-dialysis-cfpd-improves-ultrafiltration-in-children-with-acute-kidney-injury-on-conventional-pd-using-a-4-25%C3%A2-dextrose-solution
#16
Peter Nourse, Gina Sinclair, Priya Gajjar, Mandi du Plessis, Andrew Charles Argent
BACKGROUND: Criticism against the use of acute peritoneal dialysis (PD) has been its low clearance and low ultrafiltration (UF) volumes compared to extracorporeal techniques. The aim of our study was to determine whether continuous flow peritoneal dialysis (CFPD) would improve UF in children with acute kidney injury (AKI) in cases where UF on conventional PD was inadequate using 4.25 % glucose concentrations. METHODS: Five infants were prospectively studied. All had AKI with fluid overload...
July 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/26871268/has-the-use-of-cvvhdf-when-compared-to-cvvh-during-crrt-affected-the-failed-circuit-life-within-a-major-teaching-hospital-a-service-evaluation
#17
Jody Ede, Andrea Dale
BACKGROUND: A significant problem during continuous renal replacement therapy is premature circuit failure, affecting efficacy and molecular clearance. Techniques to improve circuit failure are anticoagulation, access site and modality. A modality change was introduced, moving from continuous veno-venous haemofiltration to continuous veno-venous haemodiafiltration as a result of existing issues with failing circuit times and failure rates. AIM: The aim of this service evaluation was to ascertain if the use of continuous veno-venous haemodiafiltration compared to continuous veno-venous haemofiltration had affected failed circuit survival times and rates...
February 12, 2016: Nursing in Critical Care
https://www.readbyqxmd.com/read/26640058/nucleosome-levels-and-toll-like-receptor-expression-during-high-cut-off-haemofiltration-a-pilot-assessment
#18
RANDOMIZED CONTROLLED TRIAL
Rafidah Atan, Clive May, Simon R Bailey, Marcel Tanudji, Kumar Visvanathan, Narelle Skinner, Rinaldo Bellomo, Hermann Goehl, Markus Storr
OBJECTIVES: To measure plasma nucleosome levels and expression of toll-like receptors (TLRs) in a pilot cohort of patients with severe acute kidney injury (AKI) within a randomised controlled trial of continuous venovenous haemofiltration with high cut-off filters (CVVH-HCO) v standard filters (CVVH-std). METHODS: We measured plasma nucleosome levels using the Cell Death Detection ELISA PLUS (10X) assay kit. We analysed plasma levels for correlation with disease severity and compared the effects of CVVH-HCO and CVVH-std on plasma nucleosome levels over the first 72 hours...
December 2015: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/26633605/severe-cefepime-induced-status-epilepticus-treated-with-haemofiltration
#19
A Suarez-de-la-Rica, C Hernández-Gancedo, A López-Tofiño, E Maseda, F Gilsanz
Neurotoxicity caused by cefepime may occur predominantly in patients with impaired renal function. A case of a cefepime-induced non-convulsive status epilepticus (NCSE) is presented. A 65-year-old woman suffered a severe NCSE due to cefepime in the presence of acute renal failure, requiring coma induction with sodium thiopental. A serious interaction between valproic acid (VPA) and meropenem was also produced after changing cefepime to meropenem. Continuous veno-venous haemofiltration was employed to improve cefepime clearance, and the patient progressively regained her previous mental condition...
June 2016: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/26621809/coupled-plasma-haemofiltration-filtration-in-severe-sepsis-systematic-review-and-meta-analysis
#20
REVIEW
Ian Hazzard, S Jones, T Quinn
INTRODUCTION: Coupled plasma filtration and adsorption (CPFA) has been used in the treatment of severe sepsis with the intention of removing the proinflammatory and anti-inflammatory mediators from the systemic circulation. It is believed that this interrupts and moderates the septic cascade, but there is uncertainty about the benefits of this therapy. METHODS: A systematic review and meta-analysis were performed to estimate the effects of CPFA on mortality in severe sepsis...
December 2015: Journal of the Royal Army Medical Corps
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