keyword
MENU ▼
Read by QxMD icon Read
search

Cervix cancer

keyword
https://www.readbyqxmd.com/read/28734013/cervical-cancer-in-africa-latin-america-and-the-caribbean-and-asia-regional-inequalities-and-changing-trends
#1
S Vaccarella, M Laversanne, J Ferlay, F Bray
The vast majority (86% or 453,000 cases) of the global burden of cervical cancer occurs in Africa, Latin America and the Caribbean, and Asia, where one in nine new cancer cases are of the cervix. Although the disease has become rare in high-resource settings (e.g. in North America, parts of Europe, Japan) that have historically invested in effective screening programmes, the patterns and trends are variable elsewhere. While favourable incidence trends have been recorded in many populations in Asia and Latin America and the Caribbean in the past decades, rising rates have been observed in sub-Saharan African countries, where high quality incidence series are available...
July 22, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28730962/phosphonium-salt-displays-cytotoxic-effects-against-human-cancer-cell-lines
#2
Dhanyalayam Dhanya, Giuseppe Palma, AnnaRita Cappello, Annaluisa Mariconda, Maria Stefania Sinicropi, Francesca Giordano, Vitale Del Vecchio, Anna Ramunno, Claudio Arra, Pasquale Longo, Carmela Saturnino
Aims/ Objective: Phosphonium salts are compounds whose structural characteristics enable them to cross the plasma and mitochondrial membrane with ease. Cancer cells have higher plasma membrane potentials than normal cells, phosphonium salts selectively accumulate in the mitochondria of neoplastic cells and inhibit mitochondrial function. METHOD: In the presente work, we investigate the cytotoxic activity of lipophilic phosphonium salt (11-methoxy11-oxo-undecyl) triphenylphosphonium bromide (MUTP) as well as of two new phosphine oxide salts, 3,3'-(methylphosphoryl) dibenzenaminium chloride (SBAMPO) and 3,3' (phenylphosphoryl) dibenzenaminium chloride (SBAPPO) on the proliferation of breast cancer cell line (MCF-7) and human uterin cervix adenocarcinoma cells (HeLa)...
July 19, 2017: Anti-cancer Agents in Medicinal Chemistry
https://www.readbyqxmd.com/read/28728751/a-phase-ii-evaluation-of-brivanib-in-the-treatment-of-persistent-or-recurrent-carcinoma-of-the-cervix-an-nrg-oncology-gynecologic-oncology-group-study
#3
John K Chan, Wei Deng, Robert V Higgins, Krishnansu S Tewari, Albert J Bonebrake, Michael Hicks, Stephanie Gaillard, Pedro T Ramirez, Weldon Chafe, Bradley J Monk, Carol Aghajanian
BACKGROUND: Brivanib is an oral, tyrosine kinase inhibitor against vascular endothelial growth factor (VEGF) and fibroblast growth factor receptor (FGFR). We studied its efficacy and tolerability in persistent or recurrent cervical cancer patients. METHODS: Eligible patients had at least one prior cytotoxic regimen for recurrence and with measurable disease. Brivanib 800mg was administered orally every day (1cycle=28days) until disease progression or prohibitive toxicity...
July 17, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28725247/novel-anesthetic-technique-for-combined-intracavitary-and-interstitial-brachytherapy-for-cervix-cancer-in-an-outpatient-setting
#4
Yiat Horng Leong, Kenneth Hock Soon Tan, Bok Ai Choo, Vicky Yaling Koh, Johann I-Hsiung Tang
PURPOSE: To determine the feasibility and safety of outpatient combined intracavitary and interstitial brachytherapy for cervix cancer with sedation and local anesthesia. MATERIAL AND METHODS: We included patients diagnosed with non-metastatic cervix cancer and have completed brachytherapy between December 2015 and December 2016. Moderate to deep sedation was achieved using intravenous midazolam, propofol, fentanyl, and oxycodone. Local anesthesia was achieved with 2% lignocaine gel and a paracervical block containing a mixture of 1% ropivacaine, 2% lignocaine, and 1 : 1,000 adrenaline...
June 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28721896/prognostic-importance-of-the-site-of-recurrence-in-patients-with-metastatic-recurrent-cervical-cancer
#5
Tae Hun Kim, Moon-Hong Kim, Beob-Jong Kim, Sang-Il Park, Sang-Young Ryu, Chul-Koo Cho
PURPOSE: The clinical characteristics and outcomes of patients with metastatic recurrent cervical cancer remain poorly understood. The goals of the present study were to investigate the survival outcomes according to the recurrence site in a large cohort of cervical cancer patients. METHODS AND MATERIALS: Of 1322 patients with primary cervical cancer from 2000 to 2013, 205 with recurrence after primary or adjuvant postoperative radiation were enrolled retrospectively...
August 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28720941/chemical-composition-and-bioactivity-of-essential-oils-from-flower-and-fruit-of-thymbra-capitata-and-thymus-species
#6
Jonathan Delgado-Adámez, María Garrido, Maria Elena Bote, María C Fuentes-Pérez, Javier Espino, Daniel Martín-Vertedor
Thymbra capitata and Thymus species are commonly known as thyme in Spain and they are currently used as culinary herbs, as well as for ornamental, aromatizing and traditional medicinal purposes. Given the economic importance of thyme oils, many thyme species have been studied, and their essential oils (EOs) and other volatile-containing extracts have been chemically characterized. The aim of this study was to evaluate the antioxidant, antimicrobial and cytotoxic activities as well as the phytochemical composition of the EOs from fruits and flowers of T...
June 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28720749/effects-of-intrinsic-and-extrinsic-factors-on-the-level-of-hope-and-psychological-health-status-of-patients-with-cervical-cancer-during-radiotherapy
#7
Li-Rong Li, Mei-Guang Lin, Juan Liang, Qiong-Yan Hu, Dan Chen, Meng-Ying Lan, Wu-Qing Liang, Yu-Ting Zeng, Ting Wang, Gui-Fen Fu
BACKGROUND This study aimed to explore the factors affecting the level of hope and psychological health status of patients with cervical cancer (CC) during radiotherapy. MATERIAL AND METHODS A total of 480 CC patients were recruited. Psychological distress scale, Herth hope index, functional assessment cancer therapy-cervix, and Jolowiec coping scale were used to conduct surveys on psychological distress, level of hope, quality of life (QOL), and coping style to analyze the factors affecting the level of hope and psychological health status of CC patients...
July 19, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28717824/follow-up-after-radical-vaginal-trachelectomy-rvt-patients-problems-and-physicians-difficulties
#8
Dorothee Speiser, Shazia Malik, Malgorzata Lanowska, Anne Bartens, Jens-Uwe Blohmer, Mandy Mangler
PURPOSE: Patients after radical vaginal trachelectomy (RVT) need specific follow-up treatment because their problems differ from those of other gyneco-oncologic patients. Anatomic changes after surgery complicate examinations. Recognition and treatment of these issues require physician's expertise. PATIENTS AND METHODS: We evaluated the follow-up data of 70 patients who underwent RVT for early cervical cancer between 03/2010 and 12/2013. The follow-up interval in the first 2 years was 3 and 6 months in the following 2 years...
July 17, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28713771/integrating-hyperthermia-into-modern-radiation-oncology-what-evidence-is-necessary
#9
REVIEW
Jan C Peeken, Peter Vaupel, Stephanie E Combs
Hyperthermia (HT) is one of the hot topics that have been discussed over decades. However, it never made its way into primetime. The basic biological rationale of heat to enhance the effect of radiation, chemotherapeutic agents, and immunotherapy is evident. Preclinical work has confirmed this effect. HT may trigger changes in perfusion and oxygenation as well as inhibition of DNA repair mechanisms. Moreover, there is evidence for immune stimulation and the induction of systemic immune responses. Despite the increasing number of solid clinical studies, only few centers have included this adjuvant treatment into their repertoire...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28707541/concurrent-weekly-cisplatin-versus-triweekly-cisplatin-with-radiotherapy-for-locally-advanced-squamous-cell-carcinoma-of-the-cervix-a-retrospective-analysis-from-a-single-institution
#10
Yoshino Kinjyo, Yutaka Nagai, Takafumi Toita, Wataru Kudaka, Takuro Ariga, Yuko Shimoji, Tadaharu Nakasone, Yusuke Taira, Yoshihisa Arakaki, Tomoko Nakamoto, Akihiko Wakayama, Takuma Ooyama, Hitoshi Maemoto, Joichi Heianna, Yoichi Aoki
OBJECTIVES: To compare patients with cervical cancer who were primarily treated with concurrent chemoradiotherapy (CCRT) using 20 mg/m(2) CCDP for 5 days every 3 weeks with weekly regimens of 40 mg/m(2). METHODS: We retrospectively analyzed 185 patients with Stage IB to IVA squamous cell carcinoma of the cervix who were treated with CCRT between 2005 and 2013 at our hospital. The CCRT regimen consisted of cisplatin at 20 mg/m(2) for 5 days every 3 weeks or 40 mg/m(2) weekly, administered concomitantly with RT...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28702779/clinicopathological-characteristics-of-fallopian-tube-metastases-from-primary-endometrial-cervical-and-nongynecological-malignancies-a-single-institutional-experience
#11
Kiyong Na, Hyun-Soo Kim
This study was aimed at investigating the clinicopathological characteristics of tubal metastases originating from primary endometrial, cervical, and nongynecological malignancies. We performed a 4-year retrospective study in which fallopian tube tissues obtained from 60 patients with tubal metastases were examined. In addition, we compared the number of tubal metastasis cases detected during periods of representative or whole tubal sampling. Twenty-three and 37 tubal metastases were found in cases examined after representative and whole tubal sampling techniques, respectively...
July 13, 2017: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/28702499/metastasis-of-cervical-cancer-to-breast-a-case-report-and-review-of-literature
#12
Ankit Mangla, Nikki Agarwal, Farid Saei Hamedani, Jiaxiang Liu, Shweta Gupta, Michael R Mullane
Metastasis to the breast from an extra-mammary malignancy has been documented in literature, however cervical cancer metastasis to the breast is very rare. Thirty-eight cases of metastatic deposit to the breast from cervical cancer have been reported in literature. Though most patients present with a breast lump, it is very difficult to clinically distinguish a primary breast malignancy from a metastatic deposit. Histopathology of the tissue, aided with immune-histochemical staining pattern provides a definitive diagnosis...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28702405/the-impact-of-irradiation-dose-on-the-computed-tomography-radiographic-response-of-metastatic-nodes-and-clinical-outcomes-in-cervix-cancer-in-a-low-resource-setting
#13
Matthew Ryan McKeever, Lindsay Hwang, Jennifer Barclay, Yin Xi, April Bailey, Kevin Albuquerque
INTRODUCTION: The aim of this study is to investigate the relationship between the radiation dose to pelvic and para-aortic lymph nodes, nodal response, and clinical outcomes in a resource-poor setting based on computed tomography (CT) nodal size alone. MATERIALS AND METHODS: This retrospective study from 2009 to 2015 included 46 cervical cancer patients with 133 metastatic pelvic and para-aortic lymph nodes definitively treated with chemoradiation and brachytherapy in a public hospital with limited access to positron emission tomography (PET) scans...
April 2017: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/28701894/volume-measurement-by-diffusion-weighted-imaging-in-cervical-cancer
#14
Shinya Fujii, Naoki Iwata, Chie Inoue, Naoko Mukuda, Takeru Fukunaga, Toshihide Ogawa
BACKGROUND: The aim of this paper was to evaluate the validity of tumor volume measurement using diffusion-weighted (DW) imaging in cervical cancer. METHODS: In this retrospective study, 22 patients, who underwent preoperative 3.0 T MR examinations with DW imaging were evaluated. Tumor volume measurement by oblique axial (short axis to the uterine cervix) T2-weighted imaging was performed by manually outlining the tumor on the monitor. The area of tumor in each slice was multiplied by the slice profile (slice thickness plus intersection gap), and the total tumor volume was calculated by summation of these obtained volumes...
June 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/28700433/data-set-for-the-reporting-of-carcinomas-of-the-cervix-recommendations-from-the-international-collaboration-on-cancer-reporting-iccr
#15
W Glenn McCluggage, Meagan J Judge, Isabel Alvarado-Cabrero, Máire A Duggan, Lars-Christian Horn, Pei Hui, Jaume Ordi, Christopher N Otis, Kay J Park, Marie Plante, Colin J R Stewart, Edwin K Wiredu, Brian Rous, Lynn Hirschowitz
A comprehensive pathologic report is essential for optimal patient management, cancer staging and prognostication. In many countries, proforma reports are used but the content of these is variable. The International Collaboration on Cancer Reporting is an alliance formed by the Royal Colleges of Pathologists of Australasia and the United Kingdom, the College of American Pathologists, the Canadian Partnership Against Cancer and the European Society of Pathology, for the purpose of developing standardized, evidence-based reporting data sets for each cancer site...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28700431/methods-for-measuring-and-staging-a-uterine-cervical-adenocarcinoma-showing-intracystic-papillary-growth-a-case-report
#16
Hiroshi Yoshida, Shunichi Ikeda, Takafumi Tsukada, Reiko Watanabe, Nobuyoshi Hiraoka, Tomoyasu Kato
Endocervical adenocarcinomas usually demonstrate infiltrative and/or destructive invasion, and the depth and horizontal extent of the invasion are known to have prognostic utility. Here, we report the unusual case of a patient with endocervical adenocarcinoma showing intracystic papillary growth and discuss our methods for measuring and staging this lesion. A 45-yr-old Japanese woman (gravida, 0; para, 0) underwent a cone biopsy for squamous cell carcinoma in situ and atypical glandular cells. Macroscopically, an intracystic tumor (∼7...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28698536/metformin-use-associated-with-lower-risk-of-cancer-in-patients-with-diabetes-mellitus-type-2
#17
Jasna Kusturica, Aida Kulo Ćesić, Edis Gušić, Sanita Maleškić, Maida Rakanović-Todić, Damir Šečić
Aim In order to increase the database related to the antineoplastic potential of metformin, association between the use of metformin and risk of cancer occurence in patients with diabetes mellitus type 2 (DM2) was investigated. Methods In this cross-sectional study, medical records of patients with DM2 were reviewed for cancer occurence. Data on age, body mass index (BMI), alcohol and nicotine consumption, glucose and HbA1c levels, duration of DM2, medication used in the treatment of DM2 and cancer occurence were collected and analyzed...
August 1, 2017: Medicinski Glasnik
https://www.readbyqxmd.com/read/28698340/leisure-time-physical-activity-and-circulating-25-hydroxyvitamin-d-levels-in-cancer-survivors-a-cross-sectional-analysis-using-data-from-the-us-national-health-and-nutrition-examination-survey
#18
Lin Yang, Adetunji T Toriola
OBJECTIVES: Circulating 25-hydroxyvitamin D (25-OHD) is associated with improved cancer prognosis in some studies, yet it may be a surrogate marker for physical activity. We investigated the associations of leisure-time physical activity (LTPA) with circulating 25-OHD levels in cancer survivors, and determined whether associations differ by indoor and outdoor activity. DESIGN: Cross-sectional study. SETTING: The US National Health and Nutrition Examination Survey (NHANES)...
July 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28697913/uterine-transposition-technique-and-a-case-report
#19
Reitan Ribeiro, Juliano Camargo Rebolho, Fernanda Keiko Tsumanuma, Giovana Gugelmin Brandalize, Carlos Henrique Trippia, Karam Abou Saab
OBJECTIVE: To report the first uterine transposition for fertility preservation in a patient with rectal cancer. DESIGN: Case report. SETTING: Community hospital. PATIENT(S): A 26-year-old patient with stage cT3N1M0 rectal adenocarcinoma located 5 cm from the anal margin. INTERVENTION(S): Laparoscopic transposition of the uterus to the upper abdomen, outside of the scope of radiation, was performed to preserve fertility...
July 8, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28685798/cyto-colpo-histologic-correlation-about-an-analytical-study-of-120-colposcopies
#20
Olfa Slimani, Riadh Ben Temim, Tahar Makhlouf, Nabil Mathlouthi, Leila Attia
PROBLEM: Cervical cancer is the second gynecological cancer Tunisian women after breast. This is a sexually transmitted disease including the role of HPV has been proven. Cervical cancer screening is possible due to the accessibility of the cervix with a speculum examination and implementation of cervical smear. AIM OF THE WORK: To study the epidemiological and clinical data of patients, analyze the results of the Pap test, colposcopy and cervical biopsy staging are the lesions observed in colposcopy, compare the results of smears, colposcopy and cervical biopsy...
October 2016: La Tunisie Médicale
keyword
keyword
8881
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"