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https://www.readbyqxmd.com/read/29341145/cancer-surgery-in-the-genomic-era
#1
D C Winter, M Sund
No abstract text is available yet for this article.
January 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29338721/infectious-keratoconjunctivitis-in-semi-domesticated-eurasian-tundra-reindeer-rangifer-tarandus-tarandus-microbiological-study-of-clinically-affected-and-unaffected-animals-with-special-reference-to-cervid-herpesvirus-2
#2
Javier Sánchez Romano, Torill Mørk, Sauli Laaksonen, Erik Ågren, Ingebjørg H Nymo, Marianne Sunde, Morten Tryland
BACKGROUND: Infectious keratoconjunctivitis (IKC) is one of the most common ocular diseases in ruminants worldwide. In addition to keratitis and conjunctivitis, animals with IKC can develop uveitis, corneal ulcer, and in severe cases, blindness. The bacteria Moraxella spp. has been described as the primary causative agent of infectious bovine keratoconjunctivitis (IBK) in cattle (Bos taurus), while Chlamydia spp. and Mycoplasma conjunctivae are considered the main causative agents of IKC in sheep (Ovis aries)...
January 16, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29338053/selenium-regulation-of-selenoprotein-enzyme-activity-and-transcripts-in-a-pilot-study-with-founder-strains-from-the-collaborative-cross
#3
Roger A Sunde
Rodents and humans have 24-25 selenoproteins, and these proteins contain the 21st amino acid, selenocysteine, incorporated co-translationally into the peptide backbone in a series of reactions dependent on at least 6 unique gene products. In selenium (Se) deficiency, there is differential regulation of selenoprotein expression, whereby levels of some selenoproteins and their transcripts decrease dramatically in Se deficiency, but other selenoprotein transcripts are spared this decrease; the underlying mechanism, however, is not fully understood...
2018: PloS One
https://www.readbyqxmd.com/read/29321158/response-to-calprotectin-is-not-independent-from-baseline-erosion-in-predicting-radiological-progression-in-early-rheumatoid-arthritis-by-chevreau-et-al
#4
Maria Karolina Jonsson, Nina Paulshus Sundlisæter, Hilde Haugedal Nordal, Hilde Berner Hammer, Anna-Birgitte Aga, Désirée van der Heijde, Tore Kristian Kvien, Bjørg-Tilde Svanes Fevang, Siri Lillegraven, Espen Andre Haavardsholm
No abstract text is available yet for this article.
January 10, 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29315564/circulating-anti-m%C3%A3-llerian-hormone-and-breast-cancer-risk-a-study-in-ten-prospective-cohorts
#5
Wenzhen Ge, Tess V Clendenen, Yelena Afanasyeva, Karen L Koenig, Claudia Agnoli, Louise A Brinton, Joanne F Dorgan, A Heather Eliassen, Roni T Falk, Göran Hallmans, Susan E Hankinson, Judith Hoffman-Bolton, Timothy J Key, Vittorio Krogh, Hazel B Nichols, Dale P Sandler, Minouk J Schoemaker, Patrick M Sluss, Malin Sund, Anthony J Swerdlow, Kala Visvanathan, Mengling Liu, Anne Zeleniuch-Jacquotte
A strong positive association has been observed between circulating anti-Müllerian hormone (AMH), a biomarker of ovarian reserve, and breast cancer risk in three prospective studies. Confirming this association is important because of the paucity of biomarkers of breast cancer risk in premenopausal women. We conducted a consortium study including ten prospective cohorts that had collected blood from premenopausal women. A nested case-control design was implemented within each cohort. A total of 2,835 invasive (80%) and in situ (20%) breast cancer cases were individually matched to controls (n = 3,122) on age at blood donation...
January 8, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29311634/variation-in-salinity-tolerance-between-and-within-anadromous-subpopulations-of-pike-esox-1ucius
#6
Johanna Sunde, Carl Tamario, Petter Tibblin, Per Larsson, Anders Forsman
Environmental heterogeneity is a key determinant of genetic and phenotypic diversity. Stable and homogenous environments tends to result in evolution of specialism and local adaptations, while temporally unpredictable environments may maintain a diversity of specialists, promote generalist strategies, or favour diversified bet hedging strategies. We compared salinity tolerance between two anadromous subpopulations of pike (Esox Lucius) that utilize freshwater spawning sites with different salinity regimes. Eggs from each population were artificially fertilized and incubated in a salinity gradient (0, 3, 5, 7, and 9 psu) using a split-brood design...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29306897/critical-roles-of-xirp-proteins-in-cardiac-conduction-and-their-rare-variants-identified-in-sudden-unexplained-nocturnal-death-syndrome-and-brugada-syndrome-in-chinese-han-population
#7
Lei Huang, Kuo-Ho Wu, Liyong Zhang, Qinchuan Wang, Shuangbo Tang, Qiuping Wu, Pei-Hsiu Jiang, Jim Jung-Ching Lin, Jian Guo, Lin Wang, Shih-Hurng Loh, Jianding Cheng
BACKGROUND: Sudden unexplained nocturnal death syndrome (SUNDS) remains an autopsy negative entity with unclear etiology. Arrhythmia has been implicated in SUNDS. Mutations/deficiencies in intercalated disc components have been shown to cause arrhythmias. Human cardiomyopathy-associated 1 (XIRP1) and 3 (XIRP2) are intercalated disc-associated, Xin repeats-containing proteins. Mouse Xirp1 is necessary for the integrity of intercalated disc and for the surface expression of transient outward and delayed rectifier K+ channels, whereas mouse Xirp2 is required for Xirp1 intercalated disc localization...
January 6, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29299275/using-population-viability-analysis-genomics-and-habitat-suitability-to-forecast-future-population-patterns-of-little-owl-athene-noctua-across-europe
#8
Line Holm Andersen, Peter Sunde, Irene Pellegrino, Volker Loeschcke, Cino Pertoldi
The agricultural scene has changed over the past decades, resulting in a declining population trend in many species. It is therefore important to determine the factors that the individual species depend on in order to understand their decline. The landscape changes have also resulted in habitat fragmentation, turning once continuous populations into metapopulations. It is thus increasingly important to estimate both the number of individuals it takes to create a genetically viable population and the population trend...
December 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29247118/the-missing-siblings-of-infants-born-preterm
#9
Suvi Alenius, Eero Kajantie, Reijo Sund, Pieta Näsänen-Gilmore, Marja Vääräsmäki, Mika Gissler, Petteri Hovi
BACKGROUND: Parents of very or extremely low birth weight infants have fewer subsequent children after preterm birth. Whether this applies to parents of less preterm infants is unknown. METHODS: In this nationwide cohort study, we identified all 230 308 traceable (>99%) singletons (9983 preterm, 4.3%) live born in Finland between January 1, 1987, and September 30, 1990, and their parents. Quantitative contribution of gestational age of child to the birth of parental subsequent children was assessed by multivariate Cox regression models, stratifying by the number of previous children...
January 2018: Pediatrics
https://www.readbyqxmd.com/read/29231011/-research-progress-of-the-relationship-between-sunds-and-osahs
#10
REVIEW
Y D Wu, L Y Zhang, J D Cheng
Sudden unexplained nocturnal death syndrome (SUNDS) is always a difficulty in forensic medicine researches. Although the development of molecular genetics promotes the etiologic study of SUNDS, the pathogenesis of most such cases is still unclear. Sleep apnea syndrome (SAS) is one of the common forms of sleep disorders, and obstructive sleep apnea hypopnea syndrome (OSAHS) is the most common. In recent years, some domestic and international researches show that OSAHS is related to the development of cardiovascular disease, which may cause cardiac arrhythmia, even sudden death...
February 2017: Fa Yi Xue za Zhi
https://www.readbyqxmd.com/read/29194579/targeted-gene-sequencing-and-whole-exome-sequencing-in-autopsied-fetuses-with-prenatally-diagnosed-kidney-anomalies
#11
M Rasmussen, L Sunde, M L Nielsen, M Ramsing, A Petersen, T D Hjortshøj, T E Olsen, A Tabor, J M Hertz, I Johnsen, L Sperling, O B Petersen, U B Jensen, F G Møller, M B Petersen, D L Lildballe
Identification of fetal kidney anomalies invites questions about underlying causes and recurrence risk in future pregnancies. We therefore investigated the diagnostic yield of next-generation sequencing in fetuses with bilateral kidney anomalies and the correlation between disrupted genes and fetal phenotypes. Fetuses with bilateral kidney anomalies were screened using an in-house-designed kidney-gene panel. In families where candidate variants were not identified, whole-exome sequencing was performed. Genes uncovered by this analysis were added to our kidney-panel...
November 30, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/29191110/decennial-trends-and-inequalities-in-healthy-life-expectancy-the-hunt-study-norway
#12
Siri H Storeng, Steinar Krokstad, Steinar Westin, Erik R Sund
AIMS: Norway is experiencing a rising life expectancy combined with an increasing dependency ratio - the ratio of those outside over those within the working force. To provide data relevant for future health policy we wanted to study trends in total and healthy life expectancy in a Norwegian population over three decades (1980s, 1990s and 2000s), both overall and across gender and educational groups. METHODS: Data were obtained from the HUNT Study, and the Norwegian Educational Database...
March 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29190764/selenium-requirements-based-on-muscle-and-kidney-selenoprotein-enzyme-activity-and-transcript-expression-in-the-turkey-poult-meleagris-gallopavo
#13
Rachel M Taylor, Roger A Sunde
The current NRC selenium (Se) requirement for turkeys is 0.2 μg Se/g diet. We previously fed turkey poults a Se-deficient diet (0.005 μg Se/g) supplemented with 10 graded levels of Se (0, 0.025, 0.05, 0.1, 0.2, 0.3, 0.4, 0.5, 0.75, 1.0 μg Se/g as Na2SeO3, 5/treatment) for 4 wk, and found that the minimum dietary Se requirement was 0.3 μg Se/g based on selenoprotein enzyme activity in blood, liver, gizzard and pancreas. Because the turkey is primarily a production animal, we expanded this analysis to kidney, heart, breast and thigh...
2017: PloS One
https://www.readbyqxmd.com/read/29167084/parent-s-experiences-of-their-children-suffering-febrile-seizures
#14
Emma Westin, Märta Sund Levander
PURPOSE: To explore parents' experiences of their child suffering febrile seizures. DESIGN AND METHOD: Seven mothers and four fathers with experience of one or several febrile seizures in their children were interviewed. A qualitative content analysis with an inductive approach was performed. RESULT: Five themes emerged; emotional experiences, in terms of anxiety and fear, and need for control, need for support, need for acknowledgement and need for comfort...
November 11, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29155294/long-term-survival-in-patients-with-acute-myocardial-infarction-and-out-of-hospital-cardiac-arrest-a-prospective-cohort-study
#15
Kristin M Kvakkestad, Leiv Sandvik, Geir Øystein Andersen, Kjetil Sunde, Sigrun Halvorsen
AIM: To compare short- and long-term survival in patients admitted to hospital after acute myocardial infarction (AMI) with and without out-of-hospital cardiac arrest (OHCA). METHODS: Prospective cohort study of all AMI patients admitted to Oslo University Hospital Ulleval from September 1, 2005 to December 31, 2011. All-cause mortality was obtained from the Norwegian Cause of Death Registry with censoring date December 31, 2013. Cumulative survival was assessed with the Kaplan-Meier and the Life-table method...
November 16, 2017: Resuscitation
https://www.readbyqxmd.com/read/29154725/non-aneurysmal-subarachnoid-hemorrhage-when-is-a-second-angiography-indicated
#16
Asma Bashir, Ronni Mikkelsen, Leif Sørensen, Niels Sunde
Purpose Repeat imaging in patients with non-aneurysmal subarachnoid hemorrhage (NASAH) remains controversial. We aim to report our experience with NASAH with different hemorrhage patterns, and to investigate the need for further diagnostic workup to determine the underlying cause of hemorrhage. Method We conducted a retrospective analysis of all spontaneous SAH with an initial negative computed tomography (CT) with angiography (CTA) and/or digital subtraction angiography (DSA) from October 2011 through May 2017...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/29153733/antibacterial-activity-of-endodontic-sealers-against-planktonic-bacteria-and-bacteria-in-biofilms
#17
Vasileios Kapralos, Andreas Koutroulis, Dag Ørstavik, Pia Titterud Sunde, Håkon Valen Rukke
INTRODUCTION: The aim of this study was to investigate the antibacterial activity of 4 endodontic sealers against bacteria planktonic grown or in biofilms commonly detected from persistent and secondary endodontic infections. METHODS: The antibacterial activity of the sealers AH Plus, TotalFill BC sealer, RoekoSeal, and Guttaflow 2 was investigated for planktonic grown and 24-hour-old biofilms of Enterococcus faecalis, Staphylococcus epidermidis, Staphylococcus aureus, and Streptococcus mutans...
November 15, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29141610/social-relations-and-healthcare-utilisation-among-middle-aged-and-older-people-study-protocol-for-an-implementation-and-register-based-study-in-denmark
#18
Anne Sophie Bech Mikkelsen, Rikke Lund, Maria Kristiansen
BACKGROUND: While previous research establishes an association between social relations, health and use of healthcare services among older people, how to implement this knowledge in real-life settings has received much less attention. This study will explore the relationship between social relations, health and use of healthcare services in a Danish mid-life population sample. In addition, the study will explore individual and contextual factors affecting the implementation of a group-based life story intervention aimed at establishing and strengthening social relations among older people at nursing homes in Denmark...
November 15, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29117321/the-international-glossary-on-infertility-and-fertility-care-2017
#19
Fernando Zegers-Hochschild, G David Adamson, Silke Dyer, Catherine Racowsky, Jacques de Mouzon, Rebecca Sokol, Laura Rienzi, Arne Sunde, Lone Schmidt, Ian D Cooke, Joe Leigh Simpson, Sheryl van der Poel
STUDY QUESTION: Can a consensus and evidence-driven set of terms and definitions be generated to be used globally in order to ensure consistency when reporting on infertility issues and fertility care interventions, as well as to harmonize communication among the medical and scientific communities, policy-makers, and lay public including individuals and couples experiencing fertility problems? SUMMARY ANSWER: A set of 283 consensus-based and evidence-driven terminologies used in infertility and fertility care has been generated through an inclusive consensus-based process with multiple stakeholders...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29090422/health-related-quality-of-life-and-psychological-distress-in-young-adult-survivors-of-childhood-cancer-and-their-association-with-treatment-education-and-demographic-factors
#20
Janne F Halvorsen, Anne Mari Sund, Lonnie Zeltzer, Marian Ådnanes, Heidi Jensberg, Terje A Eikemo, Bendik Lund, Odin Hjemdal, Trude Reinfjell
PURPOSE: This study investigated health-related quality of life (HRQOL) and psychological distress among young adult (YA) survivors of childhood cancer and the association of these measures with treatment, education, and demographic factors ≥ 5 years post diagnosis. METHODS: Participants included cancer survivors (n = 91) recruited through the Cancer Registry of Norway (CRN) and healthy controls (n = 223) recruited from a student population. All participants completed self-report questionnaires, and the Pediatric Quality of Life Inventory (PedsQL™) 4...
October 31, 2017: Quality of Life Research
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