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lobectomy in lung cancer

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https://www.readbyqxmd.com/read/29755103/-when-should-we-perform-surgery-for-n2-lung-cancer-induction-chemoradiotherapy-or-surgery-for-local-recurrence-or-residual-tumor-after-definitive-chemoradiotherapy
#1
Hiroyuki Ito, Haruhiko Nakayama
BACKGROUND: Standard treatment for locally advanced clinical N2 lung cancer is definitive chemoradiotherapy, and induction chemoradiotherapy(IND-CRT) followed by surgery is an option. Most of them recurs remotely within a few years after initial therapy. Patients who received salvage surgery(SAL) after definitive chemoradiotherapy had no remote relapse for some period after definitive chemoradiotherapy, thus the outcome of SAL may be better than those of IND-CRT, but the operative risks of both procedures seem to be high...
April 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29755101/-outcome-of-surgical-treatment-of-locally-advanced-lung-cancer-after-induction-chemoradiotherapy
#2
Masayuki Tanahashi, Haruhiro Yukiue, Eriko Suzuki, Naoko Yoshii, Shinsuke Kitazawa, Yasunori Kaminuma, Hiroshi Niwa
OBJECTIVE: The outcome of surgical treatment of non-small-cell lung cancer after induction chemoradiotherapy was investigated. SUBJECTS: The subjects were 74 patients with non-small-cell lung cancer who received induction chemoradiotherapy( ICRT) between 1998 and 2016. ICRT was administered to pT3 lung cancer invading the chest wall(20 patients), pT4 lung cancer invading the adjacent organ(22 patients), and cN2 lung cancer(32 patients). cN2 was confirmed by mediastinoscopy(13 patients) and endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA)(19 patients)...
April 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29755082/-pulmonary-pleomorphic-carcinoma-relapsed-after-surgery-surviving-long-term-by-chemotherapy-and-nivolumab
#3
Osamu Kawamata, Toshihiro Murata, Masashi Uda
A 60'-year-old man was referred to our hospital because of nodular shadow found at mass screening. We diagnosed the tumor as non-small cell lung cancer by transbronchial biopsy. Chest computed tomography showed a tumor shadow of 3 cm in diameter with cavity. Right middle lobectomy was performed and the pathological diagnosis was pleomorphic carcinoma of the lung. The tumor recurrence was found at 10 months after surgery, and was treated with cisplatin, docetaxel plus bevacizumab for 6 cycles. A complete remission was achieved, but regrowth at 5 months after chemotherapy was noted...
May 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29751759/association-of-body-mass-index-and-outcomes-following-lobectomy-for-non-small-cell-lung-cancer
#4
Cui Wang, Min Guo, Nan Zhang, Gongchao Wang
BACKGROUND: Obesity and overweight have become increasingly prevalent, but no consensus has been reached regarding the effect of body mass index (BMI) on surgical outcomes. In this study, we sought to examine the influence of BMI on perioperative outcomes in a large cohort of patients with non-small-cell lung cancer (NSCLC) who underwent lobectomy. METHODS: A retrospective study was conducted in 1198 patients who underwent lobectomy for primary NSCLC at Shandong Provincial Hospital between November 2006 and January 2017...
May 11, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29744048/icg-easily-detects-not-only-the-segmental-plane-but-also-the-course-and-blood-distribution-of-the-bronchial-artery-case-report
#5
Hidetaka Uramoto, Nozomu Motono
Introduction: Sublobar resection has become an acceptable alternative to lobectomy in patients with early-stage lung cancer. Most notable among these approaches is indocyanine green fluorescence (ICG) imaging. Case presentation: Operative finding showed clear green staining of the left upper lobe, S6, superior pulmonary vein, and inferior PV under fluorescence navigation. Soon, the bronchial artery of right lower bronchus showed clear green staining. Next, the whole right lower bronchus is deeply colored green...
April 2018: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/29730942/-perioperative-factors-influencing-the-tolerability-of-chemotherapy-after-lung-lobe-resection
#6
Aurél Ottlakán, Balázs Pécsy, Edit Csada, Gábor Ádám, Anikó Maráz, Bernadett Borda, György Lázár, József Furák
INTRODUCTION: Lung cancer is the leading cause of malignancy-related deaths in Hungary, involving complex surgical and oncological treatment. AIM: Factors influencing the tolerability of complete/planned and incomplete postoperative chemotherapy after surgery were analyzed. METHOD: During a 6-year period (January 1, 2011-December 31, 2016), data of 72 patients operated with lung cancer (adenocarcinoma and squamous cell carcinoma), receiving complete (4 cycles) and incomplete (<4 cycles) postoperative chemotherapy were analyzed...
May 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29725530/long-acting-muscarinic-antagonist-and-long-acting-%C3%AE-2-agonist-therapy-to-optimize-chronic-obstructive-pulmonary-disease-prior-to-lung-cancer-surgery
#7
Takashi Makino, Hajime Otsuka, Yoshinobu Hata, Satoshi Koezuka, Yoko Azuma, Kazutoshi Isobe, Keishi Sugino, Satoru Ebihara, Sakae Homma, Akira Iyoda
Bronchodilators are essential for the perioperative management of patients with chronic obstructive pulmonary disease (COPD) undergoing surgery for lung cancer. The objective of the present study was to examine whether the usage of a long-acting β2-agonist (LABA) with a long-acting muscarinic antagonist (LAMA) could optimize preoperative lung function and reduce the risk for postoperative pulmonary complications. Thirty-two consecutive patients with moderate-to-severe COPD who underwent a lobectomy for lung cancer and received preoperative LAMA (n=19) or LAMA/LABA (n=13) therapy between January 2005 and December 2015 were enrolled in this retrospective study...
May 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29723532/the-persistent-problem-of-local-regional-failure-following-surgery-for-early-stage-lung-cancer
#8
Gregory D Judy, Orit Kaidar-Person, Allison Deal, Yue Wang, Andrew Migliardi, Jason Long, Benjamin Haithcock, Lawrence B Marks
BACKGROUND: The goal of the present study is to estimate the rate of local/regional failure (LRF) following definitive surgery for early stage non-small cell lung cancer (NSCLC) (without postoperative radiation) in the era of contemporary imaging and minimally invasive surgical techniques. METHODS: Retrospectively reviewed medical records of patients with early-stage NSCLC (pathologic T1-4, N0-1) who underwent lobectomy, sleeve lobectomy, bilobectomy, or pneumonectomy with/without adjuvant chemotherapy between 2007 and 2015...
April 30, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29721052/survival-outcomes-for-patients-with-surgical-and-non-surgical-treatments-in-stages-i-iii-small-cell-lung-cancer
#9
Keying Che, Hongchang Shen, Xiao Qu, Zhaofei Pang, Yuanzhu Jiang, Shaorui Liu, Xudong Yang, Jiajun Du
Objectives: Chemotherapy and radiation therapy are the standard treatments for patients with small-cell lung cancer (SCLC). However, recent studies suggest that patients with limited stage (I-III) SCLC may benefit from surgical treatment. This study was performed to evaluate the survival outcomes of surgery for stage I-III SCLC. Methods: This analysis used data from the Surveillance, Epidemiology, and End Results (SEER) database. All stage I-III (excluding N3 and Nx) SCLC patients received a diagnosis between 2004 and 2014...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29718155/robotic-resection-of-stage-iii-lung-cancer-an-international-retrospective-study
#10
Giulia Veronesi, Bernard Park, Robert Cerfolio, Mark Dylewski, Alpert Toker, Jacques P Fontaine, Wael C Hanna, Emanuela Morenghi, Pierluigi Novellis, Frank O Velez-Cubian, Marisa H Amaral, Elisa Dieci, Marco Alloisio, Eric M Toloza
OBJECTIVES: Minimally invasive surgery is accepted for early-stage lung cancer, but its role in locally advanced disease is controversial, especially using a robotic platform. The aim of this retrospective study was to assess the safety and effectiveness of robot-assisted resection in patients with Stage IIIA non-small-cell lung cancer (NSCLC) or carcinoid tumours in the series as a whole and in different subgroups according to adjuvant treatment. METHODS: This was a retrospective multicentre study of consecutive patients with clinically evident or occult N2 disease (210 NSCLC and 13 carcinoid) who, in 2007-2016, underwent robot-assisted resection at 7 high-volume centres...
April 30, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29715162/prognostic-impact-of-postoperative-c-reactive-protein-for-non-small-cell-lung-cancer-following-lobectomy
#11
Shuichi Shinohara, Masakazu Sugaya, Takamitsu Onitsuka, Kazuhiko Machida, Masaki Matsuo, Fumihiro Tanaka
BACKGROUND/AIM: C-reactive protein (CRP) is associated with cancer progression; however, the prognostic impact of postoperative CRP remains controversial. The aim of this study was to investigate the prognostic significance of postoperative CRP in patients with resected non-small cell lung cancer (NSCLC). PATIENTS AND METHODS: A total of 198 consecutive patients with NSCLC that had undergone lobectomy were retrospectively reviewed. CRP was measured on postoperative days 1, 3, and 5...
May 2018: Anticancer Research
https://www.readbyqxmd.com/read/29715149/successful-treatment-of-growing-teratoma-syndrome-of-the-lung-by-surgical-resection-a-case-report-and-literature-review
#12
Kensuke Tanaka, Gouji Toyokawa, Tetsuzo Tagawa, Kayo Ijichi, Naoki Haratake, Fumihiko Hirai, Yoshinao Oda, Yoshihiko Maehara
Growing teratoma syndrome (GTS) of the lung is extremely rare, and there are very few reports on this condition. This is a case report of GTS of the lung that was successfully treated by resection. A 19-year-old man, who had been diagnosed with a testicular tumor, lung metastases and left hilar lymph node metastasis, underwent surgical resection for left testicular cancer. After orchiectomy and chemotherapy, the patient was successfully treated with wedge resection of the right upper lobe and left upper lobectomy...
May 2018: Anticancer Research
https://www.readbyqxmd.com/read/29715123/takotsubo-cardiomyopathy-developed-after-two-stage-surgery-for-double-primary-lung-cancer
#13
Fumihiko Kinoshita, Gouji Toyokawa, Tetsuzo Tagawa, Taichi Matsubara, Yuka Kozuma, Naoki Haratake, Shinkichi Takamori, Takaki Akamine, Fumihiko Hirai, Yoshihiko Maehara
Takotsubo cardiomyopathy (TC) is a syndrome characterized by transient local systolic dysfunction of the left ventricle with no evidence of coronary artery disease or acute plaque rupture. We present the case of 71-year-old woman who developed TC after two-stage surgery for double primary lung cancer. On computed tomography, lung nodules were identified in the left upper and right middle lobes. Based on the diagnosis of double primary lung cancer, we performed two-stage surgery (left upper lobectomy followed by right middle lobectomy)...
May 2018: Anticancer Research
https://www.readbyqxmd.com/read/29715115/preoperative-pulmonary-function-tests-pfts-and-outcomes-from-resected-early-stage-non-small-cell-lung-cancer-nsclc
#14
Daniel Almquist, Nabin Khanal, Lynette Smith, Apar Kishor Ganti
BACKGROUND: Preoperative pulmonary function tests (PFTs) predict operative morbidity and mortality after resection in lung cancer. However, the impact of preoperative PFTs on overall outcomes in surgically-resected stage I and II non-small cell lung cancer (NSCLC) has not been well studied. PATIENTS AND METHODS: This is a retrospective study of 149 patients who underwent surgical resection as first-line treatment for stage I and II NSCLC at a single center between 2003 and 2014...
May 2018: Anticancer Research
https://www.readbyqxmd.com/read/29708140/lobectomy-versus-segmentectomy-and-wedge-resection-in-the-treatment-of-stage-i-non-small-cell-lung-cancer
#15
COMMENT
Robert Dziedzic, Witold Rzyman
No abstract text is available yet for this article.
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29707376/is-laryngeal-mask-airway-general-anesthesia-feasible-for-minimally-invasive-esophagectomy
#16
Rui-Xiang Zhang, Yin Li, Xian-Ben Liu, Xi-Hua Lu, Hai-Bo Sun, Zong-Fei Wang, Shi-Lei Liu, Yan Zheng, Xiao-Fei Liu, Xiu-Xia Wu
Minimally invasive esophagectomy (MIE) has been identified as an oncological method with lower mortality and morbidity. This procedure is usually performed under general anesthesia using double endotracheal tube intubation and one-lung ventilation for a good visualization like other video-assisted thoracoscopic surgery (VATS). However, it is difficult to differentiate weather the postoperative hoarseness is caused by intubation or by recurrent laryngeal nerve injury during operation, and some complications related to intubation also are the focus of thoracic surgeons...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29707343/retrospective-study-on-video-assisted-vs-open-mediastinal-lymphadenectomy-for-non-small-cell-lung-cancer-a-propensity-matched-analysis
#17
Jianbin Zhang, Yimin Wu, Hongwei Li, Qibin Shen, Caihua Yu, Ying Chai
Background: This retrospective study is designed to compare the surgical outcomes of mediastinal lymph node (MLN) dissection between the two groups of non-small cell lung cancer (NSCLC) patients underwent lung cancer surgery through video-assisted thoracoscopic surgery (VATS) or thoracotomy, as well as classify the differences and identify the safer method between two groups. Methods: A total of 497 patients underwent pulmonary lobectomy and systemic MLN dissection were enrolled in this study...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29707335/impact-of-comorbidity-burden-on-morbidity-following-thoracoscopic-lobectomy-a-propensity-matched-analysis
#18
Ruoyu Zhang, Thomas Kyriss, Jürgen Dippon, Sebastian Ciupa, Enole Boedeker, Godehard Friedel
Background: Given the positive effect of a thoracoscopic approach on improving postoperative outcomes, it is reasonable to speculate whether an increased comorbidity burden is related to higher morbidity following thoracoscopic lobectomy. We sought to evaluate the impact of comorbidity burden on adverse postoperative outcomes in this patient population. Methods: A retrospective review of our institutional database included 512 patients undergoing thoracoscopic lobectomy for early-stage non-small cell lung cancer (NSCLC) from 2009 through 2016...
March 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29706462/cost-effectiveness-analysis-of-stereotactic-body-radiotherapy-and-surgery-for-medically-operable-early-stage-non-small-cell-lung-cancer
#19
Adrien Paix, Georges Noel, Pierre-Emmanuel Falcoz, Pierre Levy
BACKGROUND: Projections estimate an increase of 50% of the incidence of lung cancer by 2030. Early-stage non-small cell lung cancer represented 19% of NSCLC cases diagnosed in the US between 2005 and 2011. There is rising evidence in favour of lung cancer screening, which will reduce the occurrence of later-stage lung cancers while raising the incidence of early-stage NSCLC. Current guidelines state that for early-stage NSCLC, surgical resection should be performed, and stereotactic body radiotherapy (SBRT) is an option for patients who are non-medically operable...
April 26, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29701375/surgical-treatment-for-elderly-patients-with-lung-cancer
#20
Telma Calado, Mariana Antunes, Daniel Cabral, Magda Alvoeiro, Francisco Félix
INTRODUCTION: Non-small cell lung cancer is a very common disease in the elderly population and its incidence in this particular population is expected to increase further, because of the ageing of the Western population. Pulmonary resection is often not recommended in the elderly, even though they have no medical contraindications to surgery. Such patients are postulated to have a limited life expectancy, the rate of complications and perioperative death is considered to be higher than younger population...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
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