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lobectomy in lung cancer

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https://www.readbyqxmd.com/read/28331339/chronological-changes-in-lung-cancer-surgery-in-a-single-japanese-institution
#1
Haruhiko Nakamura, Hiroki Sakai, Hiroyuki Kimura, Tomoyuki Miyazawa, Hideki Marushima, Hisashi Saji
BACKGROUND: The aim of this study was to evaluate the chronological changes in epidemiological factors and surgical outcomes in patients with lung cancer who underwent surgery in a single Japanese institution. PATIENTS AND METHODS: A clinicopathological database of patients with lung cancer who underwent surgery with curative intent from January 1974 to December 2014 was reviewed. The chronological changes in various factors, including patient's age, sex, histological type, tumor size, pathological stage (p-stage), surgical method, operative time, intraoperative blood loss, 30-day mortality, and postoperative overall survival (OS), were evaluated...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28329213/postoperative-pulmonary-complications-and-rehabilitation-requirements-following-lobectomy-a-propensity-score-matched-study-of-patients-undergoing-video-assisted-thoracoscopic-surgery-versus-thoracotomy%C3%A2
#2
Paula Agostini, Sebastian T Lugg, Kerry Adams, Nelia Vartsaba, Maninder S Kalkat, Pala B Rajesh, Richard S Steyn, Babu Naidu, Alison Rushton, Ehab Bishay
OBJECTIVES: : Video-assisted thoracoscopic surgical (VATS) lobectomy is increasingly used for curative intent lung cancer surgery compared to open thoracotomy due to its minimally invasive approach and associated benefits. However, the effects of the VATS approach on postoperative pulmonary complications (PPC), rehabilitation and physiotherapy requirements are unclear; our study aimed to use propensity score matching to investigate this. METHODS: Between January 2012 and January 2016 all consecutive patients undergoing lobectomy via thoracotomy or VATS were prospectively observed...
March 8, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28329055/chylous-pericardial-effusion-after-pulmonary-lobectomy
#3
Weixiong Yang, Canqiao Luo, Zhenguo Liu, Chao Cheng
Chylous pericardial effusion is a rarely reported complication of lung cancer surgery. Here, we report a case of an elderly man who suffered chylous pericardial effusion after radical right upper lung resection for cancer. The massive chylous effusion first occurred in the pericardium, drained to the right chest after the drainage of the hydropericardium and subsequently moved back to the pericardium again. Lymphoscintigraphy examination indicated that a chylous fistula was present in the plane of the tracheal carina...
March 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28325074/lobectomy-for-lung-cancer-by-video-assisted-thoracic-surgery-in-situs-inversus
#4
Abdillah N Juma, Yan-Qing Wang, Yun Chen, Xiong Peng, Yuan Zhou, Wei Zhuang
A 62-year-old man with situs inversus totalis and non-small-cell lung cancer underwent a right lower lobectomy by video-assisted thoracoscopic surgery. Lobectomy in a situs inversus totalis patient can be performed safely using this minimally invasive procedure. Preoperative evaluation of the pulmonary artery and veins by three-dimensional computed tomography and the bronchial tree by bronchoscopy, is essential to avoid unanticipated complications during the procedure.
March 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28321808/uncommon-features-of-surgically-resected-alk-positive-cavitary-lung-adenocarcinoma-a-case-report
#5
Shinkichi Takamori, Masafumi Yamaguchi, Kenichi Taguchi, Makoto Edagawa, Shinichiro Shimamatsu, Ryo Toyozawa, Kaname Nosaki, Fumihiko Hirai, Takashi Seto, Mitsuhiro Takenoyama, Yukito Ichinose
Some features found on chest computed tomography (CT), such as central tumor location, large pleural effusion, and the absence of a pleural tail, and a patient age of less than 60 years, have been suggested to be useful in predicting anaplastic lymphoma kinase (ALK) rearrangement in patients with non-small cell lung cancer (NSCLC).A 68-year-old female patient with a history of gynecological treatment was found to have a cavitary mass in the right lower lobe on an annual chest roentgenogram. The tumor was located in the peripheral area with a pleural tail showing no pleural effusion...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28314312/surgical-resection-for-pulmonary-metastasis-from-pancreatic-and-biliary-tract-cancer
#6
Tetsuzo Tagawa, Kensaku Ito, Kengo Fukuzawa, Tatsuro Okamoto, Atsuro Yoshimura, Takahide Kawasaki, Takashi Masuda, Kentaro Iwaki, Takahiro Terashi, Masahiro Okamoto, Akio Shiromizu, Akira Motohiro, Yoshihiko Maehara
AIM: To determine the efficacy of pulmonary metastasectomy for pancreatic and biliary tract cancer. PATIENTS AND METHODS: Ten patients who underwent therapeutic pulmonary metastasectomy after resection for pancreatic and biliary tract cancer at our Institution from 2006 to 2016 were retrospectively evaluated. RESULTS: The primary site was the pancreas in four patients and biliary tract in six. Nine patients had single metastasis, and one patient had bilateral multiple metastases...
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28301349/influence-of-extent-of-lymph-node-evaluation-on-survival-for-pathologically-lymph-node-negative-non-small-cell-lung-cancer
#7
Daniel J Becker, Benjamin P Levy, Heather T Gold, Scott E Sherman, Danil V Makarov, David Schreiber, Juan P Wisnivesky, Harvey I Pass
OBJECTIVES: Despite previous retrospective reports that the number of lymph nodes resected at curative intent surgery for lung cancer correlates with overall survival (OS), no consensus exists regarding the minimal nor optimal number of lymph nodes to resect at curative lung cancer surgery. METHODS: We studied subjects in the Surveillance Epidemiology and End Results Database (SEER) diagnosed with non-small cell lung cancer between 2000 and 2011 who underwent either lobectomy or pneumonectomy and had pathologic negative nodal evaluation...
March 15, 2017: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28293012/-synchronous-triple-primary-lung-adenocarcinomas-one-of-which-showing-a-thin-walled-cavity-nodule-report-of-a-case
#8
Takefumi Doi, Toshihiko Sakamoto
A 74-year-old woman was referred to our hospital to investigate a right apical segment (S1)nodule which was increasing gradually. Chest computed tomography (CT) scan showed three lesions in right S1, posterior segment(S2) and superior segment(S6). S6 lesion was a thin-walled cavity enlarging gradually with same appearance. The S1 nodule was diagnosed as adenocarcinoma by CT guided biopsy. Since the possibility of lung cancer couldn't be denied for S6 lesion, right upper lobectomy and S6 segmentectomy with mediastinal lymph node dissection was performed...
March 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28293004/-granuloma-by-foreign-body-reaction-to-the-stapler-used-for-partial-resection-of-the-lung
#9
Shintaro Hashimoto, Naoya Yamasaki, Ryoichiro Doi, Go Hatachi, Ryoutaro Kamohara, Takuro Miyazaki, Keitaro Matsumoto, Tomoshi Tsuchiya, Mikiko Hashisako, Kazuhiro Tabata, Takeshi Nagayasu
A 66-year-old woman underwent right lower lobectomy and partial resection of the middle lobe for Stage I A double lung cancer. Five years after the operation, a routine computed tomography (CT) scan showed a mass on the staple line at the middle lobe. The mass was enlarged on CT scan after 6 months. A definitive diagnosis could not be made by bronchoscopic examination and fluoro-2-deoxy-glucose(FDG)/positron emission tomography( PET)-CT showed FDG uptake in the mass( early phase:SUVmax=3.24, late phase:SUVmax=4...
March 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28278499/recurrence-and-risk-factors-for-relapse-in-patients-with-non-small-cell-lung-cancer-treated-by-surgery-with-curative-intent
#10
Cristiana Cruz, Margarida Afonso, Bárbara Oliveiros, Alice Pêgo
INTRODUCTION: Surgery remains the potentially curative treatment for early-stage non-small cell lung cancer (NSCLC). Despite this, tumor recurrence is the most common cause of treatment failure after surgery. METHODS: Data were collected retrospectively from clinical files of patients who underwent lung surgery for NSCLC from January 2008 to December 2012 in a University Hospital. Demographic data, tumor characteristics, type of surgery and recurrence were recorded...
March 10, 2017: Oncology
https://www.readbyqxmd.com/read/28275506/current-trends-in-lung-resection-for-t1a-non-small-cell-lung-cancer-is-lobectomy-still-the-answer
#11
COMMENT
Syed S Razi, Despoina Daskalaki, Joshua Burack
No abstract text is available yet for this article.
February 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28275477/curative-resection-for-lung-cancer-in-octogenarians-is-justified
#12
Michaela Tutic-Horn, Franco Gambazzi, Gaetano Rocco, Monique Mosimann, Didier Schneiter, Isabelle Opitz, Nono Martucci, Sven Hillinger, Walter Weder, Wolfgang Jungraithmayr
BACKGROUND: Due to an increased life expectancy in a healthy aging population and a progressive incidence of lung cancer, curative pulmonary resections can be performed even in octogenarians. The present study aims to investigate whether surgery is justified in patients reaching the age of 80 years and older who undergo resection for non-small cell lung cancer (NSCLC). METHODS: In this retrospective multi-centre analysis, the morbidity, mortality and long-term survival of 88 patients (24 females) aged ≥80 who underwent complete resection for lung cancer between 2000 and 2013 were analysed...
February 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28274562/biopsy-first-lessons-learned-from-cancer-and-leukemia-group-b-calgb-140503
#13
Leslie J Kohman, Lin Gu, Nasser Altorki, Ernest Scalzetti, Linda J Veit, Jason M Wallen, Xiaofei Wang
OBJECTIVE: Cancer and Leukemia Group B 140503 is an ongoing, multicenter randomized trial assessing whether sublobar resection is equivalent to lobectomy for the treatment of stage I A non-small cell lung cancer (NSCLC) ≤2 cm in diameter. The objective of this report is to determine the reasons precluding intraoperative randomization. METHODS: From June 15, 2007, to March 22, 2013, 637 patients were preregistered to the trial. Three hundred eighty-nine were randomized successfully (61%), and 248 patients were not randomized (39%)...
February 7, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28273608/single-stage-video-assisted-thoracoscopic-surgery-right-upper-lobectomy-and-left-lower-lobectomy-for-synchronous-bilateral-lung-cancers
#14
Takahiro Iida, Tadasu Kohno, Sakashi Fujimori, Takeshi Ikeda, Souichirou Suzuki
INTRODUCTION: Single-stage bilateral radical surgery for synchronous bilateral multiple lung cancers (SBMLCs) has strong advantages; however, it is considered highly invasive. We have therefore adopted video-assisted thoracoscopic surgery (VATS) as a minimally invasive surgical maneuver for bilateral lung resection. Although there have been a few reports concerning bilateral lung resection, the safety and appropriate operative indications remain unclear, especially for bilateral VATS-lobectomy...
February 21, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28272214/genetic-characterization-drives-personalized-therapy-for-early-stage-non-small-cell-lung-cancer-nsclc-patients-and-survivors-with-metachronous-second-primary-tumor-mst-a-case-report
#15
Xingchen Ding, Linlin Wang, Xijun Liu, Xindong Sun, Jinming Yu, Xue Meng
RATIONALE: The pathogenesis and progression of lung cancer is a complicated process in which many genes take part. But molecular gene testing is typically only performed in advanced-stage non-squamous non-small-cell lung cancer (NSCLC). The value of tyrosine kinase inhibitors (TKI) administration is not widely recognized with respect to early-stage NSCLC. PATIENT CONCERNS: Here, we present a case of a man, heavy smoker who initially presented with stage IA lung adenocarcinoma (LADC)...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28270738/assessing-survival-and-grading-the-severity-of-complications-in-octogenarians-undergoing-pulmonary-lobectomy
#16
Andrew Feczko, Elizabeth McKeown, Jennifer L Wilson, Brian E Louie, Ralph W Aye, Jed A Gorden, Eric Vallières, Alexander S Farivar
Introduction. Octogenarians are at increased risk for complications after lung resection. With alternatives such as radiation, understanding the risks of surgery and associated survival are valuable. Data grading the severity of complications and long-term survival in this population is lacking. We reviewed our experience with lobectomy in octogenarians, grading complications using a validated thoracic morbidity and mortality schema. Methods. We retrospectively reviewed consecutive patients aged ≥80 undergoing lobectomy between 2004 and 2012...
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/28267977/indications-for-adjuvant-mediastinal-radiotherapy-in-surgically-resected-small-cell-lung-cancer
#17
Elliot Wakeam, Meredith Giuliani, Natasha B Leighl, Samuel R G Finlayson, Thomas K Varghese, Gail E Darling
BACKGROUND: Adjuvant mediastinal radiotherapy (AMR) is used after surgical resection for patients with small cell lung cancer (SCLC), but data guiding its use are scant. We sought to examine whether AMR was associated with an improvement in survival for resected SCLC patients and to define subpopulations who should be selected for AMR. METHODS: Patients undergoing lobectomy, pneumonectomy, and sublobar resection for SCLC were identified in the National Cancer Database (2004 to 2013)...
March 3, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28262299/high-risk-for-thoracotomy-but-not-thoracoscopic-lobectomy
#18
Laura L Donahoe, Moira de Valence, Eshetu G Atenafu, Waël C Hanna, Thomas K Waddell, Andrew F Pierre, Kazuhiro Yasufuku, Marc de Perrot, Marcelo Cypel, Shaf Keshavjee, Gail E Darling
BACKGROUND: Pulmonary lobectomy is the standard of care for resection of non-small cell lung cancer (NSCLC). Patients with compromised lung function who are considered high risk may be denied surgical treatment; thus, proper identification of those truly at high risk is critical. Video-assisted thoracic surgery (VATS) may reduce the operative risk. This study reviews our institutional experience of pulmonary lobectomy by open thoracotomy or VATS techniques in patients deemed to be high risk...
March 2, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28255781/a-non-randomized-confirmatory-trial-of-segmentectomy-for-clinical-t1n0-lung-cancer-with-dominant-ground-glass-opacity-based-on-thin-section-computed-tomography-jcog1211
#19
Keiju Aokage, Hisashi Saji, Kenji Suzuki, Tomonori Mizutani, Hiroshi Katayama, Taro Shibata, Syunichi Watanabe, Hisao Asamura
INTRODUCTION: Lobectomy has been the standard surgery for even stage I lung cancer since the validity of limited resection for stage I lung cancer was denied by the randomized study reported in 1995. The aim of this non-randomized confirmatory going on since September 2013 is to confirm the efficacy of a segmentectomy for clinical T1N0 lung cancer with dominant ground glass opacity based on thin-slice computed tomography. METHOD: A total of 390 patients from 42 Japanese institutions are recruited within 4 years...
March 2, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28251378/role-of-segmentectomy-in-treatment-of-early-stage-non-small-cell-lung-cancer
#20
Mark Hennon, Rodney J Landreneau
PURPOSE AND DESIGN: Standard treatment for early-stage non-small cell lung cancer has traditionally involved lobectomy. Historical data that demonstrates suboptimal results for sublobar resection compared to lobectomy have been challenged in recent years with retrospective data for patients with T1a disease. For patients who are not candidates for lobectomy, options for sublobar resection include wedge resection or anatomic segmentectomy. Segmentectomy has long been held to be a better cancer operation than wedge resection, and its role in treating early-stage lung cancer remains controversial in patients who are candidates for lobectomy...
March 1, 2017: Annals of Surgical Oncology
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