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citicoline, hormone

Antonino Maria Cotroneo, Alberto Castagna, Salvatore Putignano, Roberto Lacava, Fausto Fant├▓, Francesco Monteleone, Filomena Rocca, Alba Malara, Pietro Gareri
BACKGROUND: The studio di intervento nel decadimento vascolare lieve (IDEALE study) was an open multicenter Italian study, the aim of which was to assess the effectiveness and safety of oral citicoline in elderly people with mild vascular cognitive impairment. METHODS: The study was performed in 349 patients. The active or citicoline group was composed of 265 patients and included 122 men and 143 women of mean age 79.9 ┬▒ 7.8 years selected from six Italian regions...
2013: Clinical Interventions in Aging
L Parnetti, L Ambrosoli, G Abate, C Azzini, R Balestreri, L Bartorelli, A Bordin, G Crepaldi, G Cristianini, D Cucinotta
INTRODUCTION: Posatirelin (L-pyro-2-aminoadipyl-L-leucil-L-prolinamide) a new synthetic tripeptide with cholinergic, catecholaminergic and neurotrophic properties, was investigated in the treatment of Alzheimer's disease. MATERIAL AND METHODS: A multicentre, double-blind study vs citicoline (reference drug) and ascorbic acid (inactive drug) was carried out in elderly patients suffering from late-onset Alzheimer's disease. The once daily intramuscular treatment lasted for three months followed by one-month oral treatment with a placebo...
August 1995: Acta Neurologica Scandinavica
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