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adolescent adhd

L Zimmer, P Fourneret
Methylphenidate (MPH) remains the only accessible psychostimulant used in France in the attention and behavior disturbances of attention deficit disorder with or without hyperactivity (ADHD). Its prescription has been extended during the past decade to other neurodevelopmental disorders in children and adolescents, also associated with a deficit of attentional resources or, more broadly, fragility of executive functions. Despite its efficiency, validated by more than 400 randomized controlled and double-blind studies, and the good tolerance of MPH in these indications, this treatment remains limited in France because of many fears and other prejudices on the part of medical practitioners and/or families...
March 12, 2018: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
Christina A Martin, Harriet Hiscock, Nicole Rinehart, Helen S Heussler, Christian Hyde, Matthew Fuller-Tyszkiewicz, Jane McGillivray, David W Austin, Alexa Chalmers, Emma Sciberras
OBJECTIVE: To determine whether self-reported sleep hygiene practices are associated with self- and parent-reported behavioral sleep problems in adolescents with ADHD. METHOD: Participants included 79 adolescents with ADHD (13-17 years) and their parents. Adolescents were asked to report on their sleep hygiene (Adolescent Sleep Hygiene Scale) and sleep (Adolescent Sleep Wake Scale). Parents also reported on their adolescent's sleep (Sleep Disturbance Scale for Children)...
March 1, 2018: Journal of Attention Disorders
Laura C Politte, Lawrence Scahill, Janet Figueroa, James T McCracken, Bryan King, Christopher J McDougle
In a prior report, we showed that extended-release guanfacine (GEXR) is safe and effective for children with autism spectrum disorder (ASD) accompanied by ADHD symptoms. Here, we examine the impact of GEXR on oppositional behavior, anxiety, repetitive behavior, and sleep disturbance. Sixty-two subjects with ASD (53 boys, 9 girls; ages 5-14 years) were randomly assigned to GEXR (n = 30) or placebo (n = 32) for 8 weeks. Outcomes include the Home Situation Questionnaire-Modified for ASD (HSQ-ASD), Anxiety scale of the Child and Adolescent Symptom Inventory (CASI), Children's Yale-Brown Obsessive-Compulsive Scale-Modified for ASD (CYBOCS-ASD), and Children's Sleep Habits Questionnaire (CSHQ)...
February 27, 2018: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
John T Mitchell, Andrea L Howard, Katherine A Belendiuk, Traci M Kennedy, Annamarie Stehli, James M Swanson, Lily Hechtman, L Eugene Arnold, Betsy Hoza, Benedetto Vitiello, Bo Lu, Scott H Kollins, Brooke S G Molina
Introduction: Children with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for smoking cigarettes, but there is little longitudinal research on the array of smoking characteristics known to be prognostic of long-term smoking outcomes into adulthood. These variables were studied into early adulthood in a multi-site sample diagnosed with ADHD combined-type at ages 7-9.9 and followed prospectively alongside an age- and sex-matched local normative comparison group (LNCG)...
March 12, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
Rikinkumar S Patel, Priya Patel, Kaushal Shah, Mandeep Kaur, Zeeshan Mansuri, Ramkrishna Makani
Objective To determine the impact of cannabis use disorder (CUD) on the inpatient outcomes of attention deficit hyperactivity disorder (ADHD) in adolescents Background Previous studies have evaluated the impact of CUD on the health-related quality of life in ADHD patients. Methods We used the nationwide inpatient sample (NIS) from the Healthcare Cost and Utilization Project (HCUP) from years 2010--2014. We identified ADHD and cannabis use (CU) as the primary and the other diagnosis, respectively, using validated International Classification of Diseases, 9th Revision, and Clinical Modification (ICD-9--CM) codes...
January 7, 2018: Curēus
Sarah K Mesrobian, Alessandro E P Villa, Michel Bader, Lorenz Götte, Alessandra Lintas
Attention-deficit hyperactivity disorder (ADHD) is characterized by deficits in executive functions and decision making during childhood and adolescence. Contradictory results exist whether altered event-related potentials (ERPs) in adults are associated with the tendency of ADHD patients toward risky behavior. Clinically diagnosed ADHD patients ( n = 18) and healthy controls ( n = 18), aged between 18 and 29 (median 22 Yo), were screened with the Conners' Adult ADHD Rating Scales and assessed by the Mini-International Neuropsychiatric Interview, adult ADHD Self-Report Scale, and by the 60-item HEXACO Personality Inventory...
2018: Frontiers in Human Neuroscience
Serhat Türkoğlu, Fatih Hilmi Çetin
No abstract text is available yet for this article.
March 2018: Clinical Neuropharmacology
Patrick D Quinn, Kwan Hur, Zheng Chang, Eric L Scott, Erin E Krebs, Matthew J Bair, Martin E Rickert, Robert D Gibbons, Kurt Kroenke, Brian M D'Onofrio
Importance: Adults with mental health conditions are more likely than those without to receive long-term opioid therapy. Less is known about opioid therapy among adolescents, especially those with mental health conditions. Objective: To examine associations between preexisting mental health conditions and treatments and initiation of any opioid and long-term opioid therapy among adolescents. Design, Setting, and Participants: A cohort of 1 224 520 incident opioid recipients without cancer diagnoses aged 14 to 18 years at first receipt was extracted from nationwide commercial health care claims data from January 1, 2003, to December 31, 2014...
March 12, 2018: JAMA Pediatrics
Lizanne Schweren, Pieter Hoekstra, Marloes van Lieshout, Jaap Oosterlaan, Nanda Lambregts-Rommelse, Jan Buitelaar, Barbara Franke, Catharina Hartman
BACKGROUND: Methodological and ethical constraints have hampered studies into long-term lasting outcomes of stimulant treatment in individuals with attention-deficit/hyperactivity disorder (ADHD). Lasting effects may be beneficial (i.e. improved functioning even when treatment is temporarily ceased) or detrimental (i.e. worse functioning while off medication), but both hypotheses currently lack empirical support. Here we investigate whether stimulant treatment history predicts long-term development of ADHD symptoms, social-emotional functioning or cognition, measured after medication wash-out...
March 13, 2018: Psychological Medicine
Cheima Bouziane, Matthan W A Caan, Hyke G H Tamminga, Anouk Schrantee, Marco A Bottelier, Michiel B de Ruiter, Sandra J J Kooij, Liesbeth Reneman
Several diffusion tensor imaging (DTI) studies in attention deficit hyperactivity disorder (ADHD) have shown a delay in brain white matter (WM) development. Because these studies were mainly conducted in children and adolescents, these WM abnormalities have been assumed, but not proven to progress into adulthood. To provide further insight in the natural history of WM maturation delay in ADHD, we here investigated the modulating effect of age on WM in children and adults. 120 stimulant-treatment naive male ADHD children (10-12 years of age) and adults (23-40 years of age) with ADHD (according to DSM-IV; all subtypes) were included, along with 23 age and gender matched controls...
2018: NeuroImage: Clinical
A J P Bloemen, A J Oldehinkel, O M Laceulle, J Ormel, N N J Rommelse, C A Hartman
BACKGROUND: We modeled both psychopathology and executive function (EF) as bi-factor models to study if EF impairments are transdiagnostic or relate to individual syndromes, and concurrently, if such associations are with general EF or specific EF impairments. METHODS: Data were obtained from the Tracking Adolescents' Individual Lives Survey (TRAILS; N = 2230). Psychopathology was assessed with parent-report questionnaires at ages 11, 14, 16, and 19, and EF with tasks from the Amsterdam Neuropsychological Tasks program at ages 11 and 19...
March 9, 2018: Psychological Medicine
Wei Liu, Yin Ting Cheung, Tara M Brinkman, Pia Banerjee, Deokumar Srivastava, Vikki G Nolan, Hongmei Zhang, James G Gurney, Ching-Hon Pui, Leslie L Robison, Melissa M Hudson, Kevin R Krull
BACKGROUND: Prevalence of emotional, behavioral and psychiatric outcomes in child and adolescent survivors of childhood acute lymphoblastic leukemia (ALL) treated on a chemotherapy-only protocol were not well defined. METHODS: Self- and parent-reported emotional and behavioral symptoms were assessed for 161 survivors of childhood ALL (51.0% female; mean [SD] age 12.1[2.6] years; 7.5[1.6] years post-diagnosis). Age- and sex-adjusted scores were calculated for standardized measures, and compared to 90th percentile of norms...
March 9, 2018: Psycho-oncology
Nowell Zammit, Owen Falzon, Kenneth Camilleri, Richard Muscat
The timing of neural activity is an intriguing way of exposing behaviourally-relevant neural activity, as neural populations exploit transient windows of synchronized activations to exchange dynamic communications in the service of various cognitive operations. The link between neural synchrony and working memory (WM) has been supported at the theoretical and empirical level. However, findings have also shown that WM encoding is also related to significant alpha-beta desynchronization. These findings have been primarily recorded during subsequent memory effect paradigms that compare correct with incorrect encoding trials...
March 7, 2018: European Journal of Neuroscience
Kathryn J Ralph, Bradley S Gibson, Dawn M Gondoli
INTRODUCTION: Existing evidence suggests that performance- and rating-based measures of working memory (WM) correlate poorly. Although some researchers have interpreted this evidence as suggesting that these measures may be assessing distinct cognitive constructs, another possibility is that rating-based measures are related to some but not all theoretically motivated performance-based measures. The current study distinguished between performance-based measures of primary memory (PM) and secondary memory (SM), and examined the relation between each of these components of WM and parent-ratings on the WM subscale of the Behavior Rating Inventory of Executive Function (BRIEF-WM)...
March 6, 2018: Journal of Clinical and Experimental Neuropsychology
Kai-Lin Huang, Han-Ting Wei, Ju-Wei Hsu, Ya-Mei Bai, Tung-Ping Su, Cheng-Ta Li, Wei-Chen Lin, Shih-Jen Tsai, Wen-Han Chang, Tzeng-Ji Chen, Mu-Hong Chen
BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) increases the risk of suicidal behaviours through psychiatric comorbidities; however, a significant direct association has not been observed between ADHD and suicide attempts. Aims To evaluate the risk of suicide attempt in adolescents and young adults with ADHD. METHOD: Using a nationwide, population-based insurance claims database, this longitudinal cohort study enrolled 20 574 adolescents and young adults with ADHD and 61 722 age- and gender-matched controls between 2001 and 2009...
March 4, 2018: British Journal of Psychiatry: the Journal of Mental Science
Gadi Lissak
A growing body of literature is associating excessive and addictive use of digital media with physical, psychological, social and neurological adverse consequences. Research is focusing more on mobile devices use, and studies suggest that duration, content, after-dark-use, media type and the number of devices are key components determining screen time effects. Physical health effects: excessive screen time is associated with poor sleep and risk factors for cardiovascular diseases such as high blood pressure, obesity, low HDL cholesterol, poor stress regulation (high sympathetic arousal and cortisol dysregulation), and Insulin Resistance...
February 27, 2018: Environmental Research
Margaret H Sibley, Stefany J Coxe, Mileini Campez, Candance Morley, Sandra Olson, Nick Hidalgo-Gato, Elizabeth Gnagy, Andrew Greiner, Erika K Coles, Timothy Page, William E Pelham
Spikes in symptom severity are noted for adolescents with attention deficit/hyperactivity disorder (ADHD) at the transitions to middle and high school that are attributed to developmental maladjustment. This study evaluated the effectiveness of high-intensity (HI; 412 hr, $4,373 per participant) versus low-intensity (LI; 24 hr, $97 per participant) skills-based summer intervention delivered to adolescents with ADHD by local school district staff. Participants were 325 ethnically diverse rising sixth and ninth graders with ADHD randomized to HI versus LI (n = 218) or recruited into an untreated comparison group (n = 107)...
March 2018: Journal of Clinical Child and Adolescent Psychology
Sabina Millenet, Manfred Laucht, Erika Hohm, Christine Jennen-Steinmetz, Sarah Hohmann, Martin H Schmidt, Günter Esser, Tobias Banaschewski, Daniel Brandeis, Katrin Zohsel
Reports of current ADHD symptoms in adults with a childhood diagnosis of ADHD are often discrepant: While one subgroup reports a particularly high level of current ADHD symptoms, another reports-in contrast-a very low level. The reasons for this difference remain unclear. Although sex might play a moderating role, it has not yet been examined in this regard. In an epidemiological cohort study from birth to young adulthood, childhood ADHD diagnoses were assessed at the ages of 4.5, 8, and 11 years based on parent ratings...
March 1, 2018: European Child & Adolescent Psychiatry
Berit Hjelde Hansen, Beate Oerbeck, Benedicte Skirbekk, Beáta Éva Petrovski, Hanne Kristensen
BACKGROUND: Accurate prevalence rates of the neurodevelopmental disorders (ND) and comorbid conditions in child and adolescent mental health services (CAMHS) are essential for treatment planning and organization of health care. However, valid and reliable prevalence estimates from Nordic CAMHS populations are scarce, and the published findings vary. AIMS: To report prevalence rates of ND (attention-deficit hyperactivity disorder: ADHD, tic disorder: TD or autism spectrum disorder: ASD) and comorbid disorders by a validated diagnostic instrument in children referred to CAMHS outpatient clinics...
February 28, 2018: Nordic Journal of Psychiatry
Francesca Rizzo, Ester Nespoli, Alireza Abaei, Izhar Bar-Gad, Dinesh K Deelchand, Jörg Fegert, Volker Rasche, Bastian Hengerer, Tobias M Boeckers
Tourette's syndrome (TS) is a neurodevelopmental disorder characterized primarily by motor and vocal tics. Comorbidities such as attention deficit and hyperactivity disorder (ADHD) are observed in over 50% of TS patients. We applied aripiprazole in a juvenile rat model that displays motor tics and hyperactivity. We additionally assessed the amount of ultrasonic vocalizations (USVs) as an indicator for the presence of vocal tics and evaluated the changes in the striatal neurometabolism using in vivo proton magnetic resonance spectroscopy (1H-MRS) at 11...
2018: Frontiers in Neurology
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