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https://www.readbyqxmd.com/read/28101160/facile-mechanical-shaking-method-is-an-improved-isolation-approach-for-islet-preparation-and-transplantation
#1
Nina Yin, Tao Chen, Yuling Yu, Yongming Han, Fei Yan, Zhou Zheng, Zebin Chen
Successful islet isolation is crucial for islet transplantation and cell treatment for type 1 diabetes. Current isolation methods are able to obtain 500-1,000 islets per rat, which results in a waste of ≥50% of total islets. In the present study, a facile mechanical shaking method for improving islet yield (up to 1,500 per rat) was developed and summarized, which was demonstrated to be more effective than the existing well-established stationary method. The present results showed that isolated islets have a maximum yield of 1,326±152 when shaking for 15 min for the fully-cannulated pancreas...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28099283/the-characteristics-of-excimer-laser-refractive-surgery-candidates
#2
Hassan Hashemi, Mehdi Khabazkhoob, Reza Pakzad, Abbasali Yekta, Marzieh Nojomi, Payam Nabovati
PURPOSE: To determine the demographic and refractive characteristics of excimer laser refractive surgery candidates in Iran. METHODS: This was a cross-sectional study between 2010 and 2014. All information was collected from 28 centers randomly selected from 12 provinces. Then, for each season of the year, one week was chosen through simple random selection, and within each week, 3 days were again chosen randomly. All excimer laser surgical procedures performed during these 3 days were identified by training staff, and data were extracted from patient charts...
January 17, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28096654/comparison-of-visian-toric-collamer-lens-and-toric-acrylic-intraocular-lens-implantation-for-the-treatment-of-myopia-with-astigmatism
#3
Hatem Ammar, Mohamed Anbar, Marwa M Abdellah
PURPOSE: To compare the efficacy and outcome of phakic toric implantable collamer lens (TICL) and refractive clear lens extraction with AcrySof Toric intraocular lens (TIOL) implantation for the treatment of myopic astigmatism. PATIENTS AND METHODS: This study assessed eyes with myopic astigmatism >-1 D and ≤-4 D with a spherical equivalent >10 D or <10 D if the patients were unsuitable for corneal refractive surgery. These eyes were divided into group A, in which Visian Toric ICL™ Phakic TICL was implanted, and group B, which involved clear lens extraction with implantation of an AcrySof IQ toric SN60T3-9™ IOL...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28096650/refractive-and-visual-outcomes-after-keraring-intrastromal-corneal-ring-segment-implantation-for-keratoconus-assisted-by-femtosecond-laser-at-6-months-follow-up
#4
Mohamed A Heikal, Marwa Abdelshafy, Tarek T Soliman, Abdelmonem M Hamed
PURPOSE: We attempted to evaluate the efficacy of femtosecond laser-assisted intrastromal corneal ring segment implantation in patients with keratoconus (KC). PATIENTS AND METHODS: A retrospective interventional consecutive clinical study was conducted on patients with KC who were treated with femtosecond laser Keraring implantation. All procedures were performed at Ebsar Eye Center in the period from January 5, 2015, to February 28, 2016. RESULTS: Thirty eyes of 20 patients were included in this study...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28095867/effects-of-ablation-depth-and-repair-time-on-the-corneal-elastic-modulus-after-laser-in-situ-keratomileusis
#5
Xiaojun Wang, Xiaona Li, Weiyi Chen, Rui He, Zhipeng Gao, Pengfei Feng
BACKGROUND: The biomechanical properties of the cornea should be taken into account in the refractive procedure in order to perform refractive surgery more accurately. The effects of the ablation depth and repair time on the elastic modulus of the rabbit cornea after laser in situ keratomileusis (LASIK) are still unclear. METHODS: In this study, LASIK was performed on New Zealand rabbits with different ablation depth (only typical LASIK flaps were created; residual stroma bed was 50 or 30% of the whole cornea thickness respectively)...
January 17, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28091897/comparative-analysis-of-the-visual-and-refractive-outcomes-of-a-refractive-segmented-multifocal-intraocular-lens-with-and-without-toricity-1-year-results
#6
Ryo Shodai, Kazuno Negishi, Hiroyuki Arai, Ikuko Toda, Hidemasa Torii, Kazuo Tsubota
PURPOSE: To compare the visual and refractive outcomes up to 1 year postoperatively following implantation of a refractive segmented or a refractive segmented toric multifocal intraocular lens (IOL). METHODS: This retrospective study included 108 eyes of 64 patients who underwent cataract surgery with implantation of a refractive segmented multifocal IOL (Lentis Mplus LS-313 MF30 IOL) (LM group) and 81 eyes of 49 patients with implantation of a refractive segmented toric multifocal IOL (Lentis Mplus LU-313 MF30T IOL) (LMT group)...
January 13, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28079222/infrared-characterisation-of-acetonitrile-and-propionitrile-aerosols-under-titan-s-atmospheric-conditions
#7
C Ennis, R Auchettl, M Ruzi, E G Robertson
Pure, crystalline acetonitrile (CH3CN) and propionitrile (CH3CH2CN) particles were formed in a collisional cooling cell allowing for infrared (IR) signatures to be compiled from 50 to 5000 cm(-1). The cell temperature and pressure conditions were controlled to simulate Titan's lower atmosphere (80-130 K and 1-100 mbar), allowing for the comparison of laboratory data to the spectra obtained from the Cassini-Huygens mission. The far-IR features confirmed the morphology of CH3CN aerosols as the metastable β-phase (monoclinic) ice, however, a specific crystalline phase for CH3CH2CN could not be verified...
January 12, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28068449/repeated-cross-linking-after-a-short-time-does-not-provide-any-additional-biomechanical-stiffness-in-the-mouse-cornea-in-vivo
#8
David Tabibian, Sabine Kling, Arthur Hammer, Olivier Richoz, Farhad Hafezi
PURPOSE: To study whether repeated collagen cross-linking (CXL) performed in vivo in mice shows an additive effect on mechanical corneal stiffness. METHODS: In this experimental study, epithelium-off CXL was performed in a total of 18 eyes from male C57BL/6 mice, with 0.27%-riboflavin solution applied for 20 minutes, followed by ultraviolet-A (UVA) irradiation (365 nm, 9mW/cm(2)) for 2:50 minutes (fluence 1.53 J/cm(2)). CXL was performed as either a single (1×CXL) or a repeated (2×CXL) treatment...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28068444/effectiveness-of-an-eyelid-thermal-pulsation-procedure-to-treat-recalcitrant-dry-eye-symptoms-after-laser-vision-correction
#9
Craig S Schallhorn, Julie M Schallhorn, Stephen Hannan, Steven C Schallhorn
PURPOSE: To provide an initial retrospective evaluation of the effectiveness of a thermal pulsation system to treat intractable patient-reported dye eye symptoms following laser vision correction. METHODS: A total of 109 eyes of 57 patients underwent thermal pulsation therapy (LipiFlow; TearScience, Morrisville, NC) for the treatment of dry eye symptoms following laser vision correction. A standardized dry eye questionnaire, the Standard Patient Evaluation of Eye Dryness (SPEED II), was administered to all patients before and after thermal pulsation therapy...
January 1, 2017: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/28059361/fabry-perot-description-for-mie-resonances-of-rectangular-dielectric-nanowire-optical-resonators
#10
Patrick E Landreman, Hamidreza Chalabi, Junghyun Park, Mark L Brongersma
We show that a dielectric nanowire (NW) with a rectangular cross section can effectively be modeled as a Fabry-Perot cavity formed by truncating a dielectric slab waveguide. By calculating the mode indices of the supported waveguide modes and the reflection phase pickup of the guided waves from the end facets, we can numerically predict the spectral locations of optical, Mie-like resonances for such NWs. This type of analysis must be performed twice in order to account for all resonances of these structures, corresponding to light propagating in the vertical or horizontal directions...
December 26, 2016: Optics Express
https://www.readbyqxmd.com/read/28034710/a-multicenter-prospective-cohort-study-on-refractive-surgery-in-15011-eyes
#11
Kazutaka Kamiya, Akihito Igarashi, Ken Hayashi, Kazuno Negishi, Masaki Sato, Hiroko Bissen-Miyajima
PURPOSE: To assess the clinical outcomes of currently used refractive surgery procedures performed in 2015. DESIGN: Prospective, multicenter cohort study. METHODS: This prospective study included 15,011 eyes of 7622 consecutive patients who underwent laser in situ keratomileusis (LASIK), surface ablation, refractive lenticule extraction (ReLEx), or phakic intraocular lens (IOL) implantation at 42 major institutions. We determined the safety, efficacy, predictability, stability, and adverse events of these surgeries preoperatively and at 1 week and 1 and 3 months postoperatively...
December 26, 2016: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28030877/an-alternative-clinical-routine-for-subjective-refraction-based-on-power-vectors-with-trial-frames
#12
Antonia María Revert, Maria Amparo Conversa, César Albarrán Diego, Vicente Micó
PURPOSE: Subjective refraction determines the final point of refractive error assessment in most clinical environments and its foundations have remained unchanged for decades. The purpose of this paper is to compare the results obtained when monocular subjective refraction is assessed in trial frames by a new clinical procedure based on a pure power vector interpretation with conventional clinical refraction procedures. METHODS: An alternative clinical routine is described that uses power vector interpretation with implementation in trial frames...
January 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28003982/assessment-of-contrast-sensitivity-loss-after-intrastromal-femtosecond-laser-and-lasik-procedure
#13
Elsa L C Mai, Ie-Bin Lian, David C K Chang
AIM: To assess the loss of contrast sensitivity (CS) function for INTRACOR or intrastromal femtosecond laser presbyopia procedure to conventional LASIK procedures. METHODS: Patients were recruited from a refractive surgery center for either INTRACOR or conventional LASIK. INTRACOR was performed on 8 eyes and LASIK was performed for 40 eyes in an overlapping period. Pre-operative evaluation and post-operative follow up for up to three months was done. Drops of CS in 4 spatial frequency (3 cpd, 6 cpd, 12 cpd and 18 cpd) right before and 3mo after the surgery were compared by Wilcoxon signed ranks test...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28002107/astigmatism-correction-with-toric-intraocular-lenses-in-descemet-membrane-endothelial-keratoplasty-triple-procedures
#14
Hideaki Yokogawa, P James Sanchez, Zachary M Mayko, Michael D Straiko, Mark A Terry
PURPOSE: To report the clinical efficacy of astigmatism correction with toric intraocular lenses (IOLs) in patients undergoing the Descemet membrane endothelial keratoplasty (DMEK) triple procedure and to evaluate the accuracy of the correction. METHODS: Fifteen eyes of 10 patients who received cataract extraction, toric IOL placement, and DMEK surgery for Fuchs corneal dystrophy and cataracts were evaluated. The cylinder power of toric IOLs was determined by an online toric calculator with keratoscopy measurements obtained using Scheimpflug corneal imaging...
December 20, 2016: Cornea
https://www.readbyqxmd.com/read/27999294/phase-and-index-of-refraction-imaging-by-hyperspectral-reflectance-confocal-microscopy
#15
Stefano Selci
A hyperspectral reflectance confocal microscope (HSCM) was realized by CNR-ISC (Consiglio Nazionale delle Ricerche-Istituto dei Sistemi Complessi) a few years ago. The instrument and data have been already presented and discussed. The main activity of this HSCM has been within biology, and reflectance data have shown good matching between spectral signatures and the nature or evolution on many types of cells. Such a relationship has been demonstrated mainly with statistical tools like Principal Component Analysis (PCA), or similar concepts, which represent a very common approach for hyperspectral imaging...
December 16, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27984063/off-axis-astigmatism-in-the-isolated-chicken-crystalline-lens
#16
Felix Maier, Siegfried Wahl, Frank Schaeffel
The chicken eye was previously found to have little off-axis astigmatism which is not explained by its special corneal shape but rather by the optical properties of the crystalline lens. To learn more about lens design, we studied off-axis astigmatism in the chicken lens in situ and compared it to a glass lens of similar power but with homogenous refractive index. After euthanasia, enucleated eye balls were cut in the equatorial plane right behind the scleral ossicles. The anterior segment was placed in a water-filled chamber...
October 28, 2016: Vision Research
https://www.readbyqxmd.com/read/27983608/refractive-index-sensing-with-d-shaped-plastic-optical-fibers-for-chemical-and-biochemical-applications
#17
Filipa Sequeira, Daniel Duarte, Lúcia Bilro, Alisa Rudnitskaya, Maria Pesavento, Luigi Zeni, Nunzio Cennamo
We report the optimization of the length of a D-shaped plastic optical fiber (POF) sensor for refractive index (RI) sensing from a numerical and experimental point of view. The sensing principle is based on total internal reflection (TIR). POFs with 1 mm in diameter were embedded in grooves, realized in planar supports with different lengths, and polished to remove the cladding and part of the core. All D-shaped POF sensors were tested using aqueous medium with different refractive indices (from 1.332 to 1...
December 13, 2016: Sensors
https://www.readbyqxmd.com/read/27975341/refractive-lenticule-implantation-for-correction-of-ametropia-case-reports-and-literature-review
#18
A Lazaridis, A Messerschmidt-Roth, W Sekundo, S Schulze
The ReLEx® technique allows correction of refractive errors through the creation and extraction of refractive stromal lenticules. Contrary to excimer laser corneal refractive procedures, where the stromal tissue is photoablated, the extracted lenticules obtained with ReLEx® can be preserved. Recent studies and case reports have described autologous re-implantation and allogeneic implantation of refractive lenticules into femtosecond-laser created stromal pockets in order to reverse the refractive outcome of a myopic corneal refractive procedure, correct hyperopia, aphakia, presbyopia and treat keratoconus...
December 14, 2016: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/27956284/myopia-correction-with-transepithelial-photorefractive-keratectomy-versus-femtosecond-assisted-laser-in-situ-keratomileusis-one-year-case-matched-analysis
#19
Michiel H A Luger, Tobias Ewering, Samuel Arba-Mosquera
PURPOSE: To compare the postoperative clinical outcomes of single-step transepithelial photorefractive keratectomy (PRK) and femtosecond-assisted laser in situ keratomileusis (LASIK). SETTING: Bergman Clinics, Utrecht, the Netherlands. DESIGN: Retrospective case series. METHODS: The eyes of consecutive patients who had transepithelial PRK were retrospectively compared with the same number of case-matched eyes (based on the preoperative refractive components) treated with femtosecond-assisted LASIK...
November 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27943250/multifocal-versus-monofocal-intraocular-lenses-after-cataract-extraction
#20
REVIEW
Samantha R de Silva, Jennifer R Evans, Varo Kirthi, Mohammed Ziaei, Martin Leyland
BACKGROUND: Good unaided distance visual acuity (VA) is now a realistic expectation following cataract surgery and intraocular lens (IOL) implantation. Near vision, however, still requires additional refractive power, usually in the form of reading glasses. Multiple optic (multifocal) IOLs are available which claim to allow good vision at a range of distances. It is unclear whether this benefit outweighs the optical compromises inherent in multifocal IOLs. OBJECTIVES: To assess the visual effects of multifocal IOLs in comparison with the current standard treatment of monofocal lens implantation...
December 12, 2016: Cochrane Database of Systematic Reviews
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