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https://www.readbyqxmd.com/read/27900347/isolated-dysphagia-as-initial-sign-of-anti-iglon5-syndrome
#1
Jens Burchard Schröder, Nico Melzer, Tobias Ruck, Anna Heidbreder, Ilka Kleffner, Ralf Dittrich, Paul Muhle, Tobias Warnecke, Rainer Dziewas
OBJECTIVE: To report on dysphagia as initial sign in a case of anti-IgLON5 syndrome and provide an overview of the current literature. METHODS: The diagnostic workup included cerebral MRI, fiber optic endoscopic evaluation of swallowing (FEES) with the FEES tensilon test, a videofluoroscopic swallowing study, evoked potentials and peripheral nerve conduction studies, polysomnography, lumbar puncture, and screening for neural autoantibodies. A systematic review of all published cases of IgLON5 syndrome is provided...
January 2017: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/27878065/corticobulbar-tract-involvement-in-neuropsychiatric-systemic-lupus-erythematosus-a-case-report
#2
Ho Kyun Kim, Mun Han, Hui Joong Lee
A 36-year-old woman, diagnosed with systemic lupus erythematosus (SLE), showed bulbar symptoms including impaired memory, slurred speech and swallowing difficulty 7 days before admission. Magnetic resonance imaging (MRI) showed symmetric confluent hyperintensities in the bilateral cerebral white matter on T2 weighted imaging (T2-WI), extended into the genu of the internal capsule and the crus cerebri of the midbrain. MR spectroscopy showed increased choline and decreased N-acetyl aspartate (NAA) peak and positron emission computed tomography (PET CT) showed decreased fluorodeoxyglucose (FDG) uptake on the lateral portion of the frontal lobe, suggesting demyelination of the white matter...
July 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27812617/analysis-of-speech-and-tongue-motion-in-normal-and-post-glossectomy-speaker-using-cine-mri
#3
Jinhee Ha, Iel-Yong Sung, Jang-Ho Son, Maureen Stone, Robert Ord, Yeong-Cheol Cho
Objective: Since the tongue is the oral structure responsible for mastication, pronunciation, and swallowing functions, patients who undergo glossectomy can be affected in various aspects of these functions. The vowel /i/ uses the tongue shape, whereas /u/ uses tongue and lip shapes. The purpose of this study is to investigate the morphological changes of the tongue and the adaptation of pronunciation using cine MRI for speech of patients who undergo glossectomy. Material and Methods: Twenty-three controls (11 males and 12 females) and 13 patients (eight males and five females) volunteered to participate in the experiment...
September 2016: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/27784474/-clinical-features-and-gene-mutations-in-epilepsy-of-infancy-with-migrating-focal-seizures
#4
K W Shang, Y H Zhang, X L Yang, A J Liu, Z X Yang, X Y Liu, Y W Jiang, X R Wu
Objective: To summarize the clinical features and gene mutations of epilepsy of infancy with migrating focal seizures (EIMFS). Method: Clinical features and electroencephalograms(EEG)of 9 patients with EIMFS of Peking University First Hospital from May 2015 to January 2016 were analyzed. Candidate gene mutations were screened by next generation sequencing. Result: Among the 9 patients, 3 were males and 6 were females. Two patients had family history. Seizure onset age was 2 days to 3 months after birth (median age 35 days)...
October 2, 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27770070/evaluation-of-dysphagia-by-novel-real-time-mri
#5
Arno Olthoff, Per-Ole Carstens, Shuo Zhang, Eva von Fintel, Tim Friede, Joachim Lotz, Jens Frahm, Jens Schmidt
OBJECTIVE: To assess safety and feasibility of real-time (RT) MRI for evaluation of dysphagia and to compare this technique to standard assessment by flexible endoscopic evaluation of swallowing (FEES) and videofluoroscopy (VF) in a cohort of patients with inclusion body myositis (IBM). METHODS: Using RT-MRI, FEES, and VF, an unselected cohort of 20 patients with IBM was studied as index disease with a uniform dysphagia. Symptoms of IBM and dysphagia were explored by standardized tools including Swallowing-Related Quality of Life Questionnaire (SWAL-QoL), IBM Functional Rating Scale, Patient-Reported Functional Assessment, and Medical Research Council Scale...
November 15, 2016: Neurology
https://www.readbyqxmd.com/read/27765110/-fourth-branchial-cleft-deformity-with-skin-orifice-a-series-of-10-cases
#6
S L Huang, B Zhang, L S Chen, L Liang, X N Luo, Z M Lu, S Y Zhang
Objective: To report rare cases of congenital neck cutaneous sinus with an orifice near the sternoclavicular joint and to investigate their origins and managements. Methods: A total of ten patients with congenital neck cutaneous sinus having an orifice near the sternoclavicular joint treated in the Guangdong General Hospital from January 2010 to June 2015 were retrospectively analyzed. Results: There four boys and six girls, aging from 11 months to 96 months with an average of 33.4 months, and they had a common feature showing a congenital cutaneous sinus with an orifice near sternoclavicular joint...
October 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27703110/-isolated-severe-dysphagia-associated-with-medial-medullary-infarction-a-case-report-and-review-of-the-literature
#7
Keiko Tamaki, Jun Tsugawa, Takeshi Murakami, George Umemoto, Yoshio Tsuboi
A 59-year-old man developed a sudden onset of vertigo and nausea, and after a few hours, he could not swallow at all. On admission, neurological examination revealed severe dysphagia associated with other transient and mild neurological deficits, including left facial paresis, and hypesthesia in the right side of his body. MRI with diffusion weighted imaging showed a hyperintense signal lesion at the left rostral medial region of the medulla, prompting the diagnosis of an acute medial medullary infarction. His facial paresis and hypesthesia disappeared within 2 weeks...
October 2016: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/27687293/real-time-mri-of-swallowing-intraoral-pressure-reduction-supports-larynx-elevation
#8
Arno Olthoff, Arun A Joseph, Matthias Weidenmüller, Blake Riley, Jens Frahm
The reduction in intraoral pressure during swallowing has previously been linked to bolus transport, although no such relation has yet been proven. The purpose of this work was to evaluate the time course of intraoral pressure during swallowing using simultaneous real-time magnetic resonance imaging (MRI) and dynamic pressure recordings. Real-time MRI based on highly undersampled radial fast low-angle shot (FLASH) and regularized nonlinear inverse reconstruction was performed at 3 T using a standard head coil and a mid-sagittal section covering the entire oral cavity...
September 30, 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27686304/frequency-of-post-stroke-dysphagia-in-pakistan-a-hospital-based-study
#9
Fazaila Ehsaan, Muhammad Sikander Ghayas Khan, Sumera Nawaz Malik, Sana Kanwal
OBJECTIVE: Purpose of the study is to determine the frequency of dysphagia after stroke and to see the factors associated with it. METHODS: Cross Sectional study design was used by including individuals pre-diagnosed as stroke on the basis of CT scan or MRI findings. Study was conducted in three hospitals of Lahore within six months. Sample size of 150 patients of any age and both gender was taken by using convenient sampling technique. To assess the conscious level, Glasgow coma scale was administered and those who scored mild or moderate on GCS were included in the study...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27583413/laryngeal-elevation-velocity-and-aspiration-in-acute-ischemic-stroke-patients
#10
Jing Zhang, Yun Zhou, Na Wei, Bo Yang, Anxin Wang, Hai Zhou, Xingquan Zhao, Yongjun Wang, Liping Liu, Melody Ouyoung, Brenda Villegas, Michael Groher
OBJECTIVES: Aspiration after stroke has been associated with aspiration pneumonia, which contributes to increased mortality of stroke. Laryngeal elevation is a core mechanism for protection from aspiration. Few studies have explored the predictive value of laryngeal elevation velocity for aspiration after stroke. This study aimed to explore the ability of laryngeal elevation velocity to predict aspiration in patients with acute ischemic stroke. METHODS: This was a prospective cohort study that included consecutive acute ischemic stroke patients treated at a teaching hospital during a 10-month period...
2016: PloS One
https://www.readbyqxmd.com/read/27559425/nigrosome-1-on-susceptibility-weighted-imaging-to-differentiate-parkinson-s-disease-from-atypical-parkinsonism-an-in-vivo-and-ex-vivo-pilot-study
#11
Frederick J A Meijer, Stefan C Steens, Anouke van Rumund, Anne-Marie van Cappellen van Walsum, Benno Küsters, Rianne A J Esselink, Marcel M Verbeek, Bastiaan R Bloem, Bożena Goraj
BACKGROUND: Previous case-control studies have suggested that the absence of a swallow-tail appearance in the substantia nigra on high-resolution SWI, representing nigrosome-1, has high accuracy to identify Parkinson's disease (PD). The first goal of our study was to evaluate nigrosome-1 ex vivo using optimized high-resolution susceptibility sensitive MRI. Our second goal was to evaluate its diagnostic value in vivo using a clinical 3T SWI sequence to differentiate between PD and atypical parkinsonism (AP) in a cohort of patients with early-stage parkinsonism...
2016: Polish Journal of Radiology
https://www.readbyqxmd.com/read/27534085/-case-control-study-on-zero-profile-implant-for-anterior-cervical-discectomy-and-fusion-and-conventional-cage-plate-internal-fixation-for-the-treatment-of-single-segmental-cervical-intervertebral-disc-herniation
#12
Hai-yu Shao, Jun Zhang, Di Yang, Jin-ping Chen, Ya-zeng Huang
OBJECTIVE: To compare clinical efficacy of Zero-profile implant for anterior cervical discectomy and fusion and conventional titanium plate with cage internal fixation for the treatment of single segmental cervical intervertebral disc herniation. METHODS: From August 2011 to March 2014, clinical data of 139 patients with single cervical disc herniation treated with anterior cervical discectomy and interbody fusion with internal fixation were retrospectively analyzed...
June 2016: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/27524383/microvascular-reconstruction-of-the-tongue-using-a-free-anterolateral-thigh-flap-three-dimensional-evaluation-of-volume-loss-after-radiotherapy
#13
Achille Tarsitano, Salvatore Battaglia, Riccardo Cipriani, Claudio Marchetti
The goal of tongue microvascular reconstruction is to maximise oral function with less morbidity while preserving speech and swallowing. This kind of reconstruction often requires a bigger flap volume than is actually needed to repair the defect. This is because every reconstructive flap is subject to a shrinking process due to oedema reduction and differences among individual tissue healing processes. Moreover, patients with advanced cancers often need adjuvant radiation therapy, which can result in further flap volume loss...
September 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27522149/retropharyngeal-liposarcoma-a-rare-cause-of-dysphagia
#14
O Vella, A Bequignon, F Comoz, E Babin
INTRODUCTION: Liposarcoma is a rare malignant mesenchymal tumour. Very few cases of retropharyngeal liposarcoma have been reported in the literature. SUMMARY: A 30-year-old woman with no notable history reported swallowing disorders for the past year associated with dysphonia. Nasal endoscopic examination demonstrated a tumour arising from the left lateral pharyngeal wall, ascending as far as the junction of the free margin of the epiglottis, aryepiglottic fold, and pharyngoepiglottic fold and obliterating the ipsilateral pyriform sinus with preservation of cord mobility...
December 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/27512221/anterior-cervical-discectomy-and-fusion-for-noncontiguous-cervical-spondylotic-myelopathy
#15
Sun Qizhi, Li Peijia, Sun Lei, Chen Junsheng, Li Jianmin
BACKGROUND: Noncontiguous cervical spondylotic myelopathy (CSM) is a special degenerative disease because of the intermediate normal level or levels between supra and infraabnormal levels. Some controversy exists over the optimal procedure for two noncontiguous levels of CSM. The study was to evaluate the outcomes of the anterior cervical discectomy and fusion (ACDF) with zero-profile devices for two noncontiguous levels of CSM. MATERIALS AND METHODS: 17 consecutive patients with two noncontiguous levels of CSM operated between December 2009 and August 2012 were included in the study...
July 2016: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/27497399/chiari-malformations-an-important-cause-of-pediatric-aspiration
#16
Jennifer C Fuller, Sumi Sinha, Paul A Caruso, Cheryl J Hersh, William E Butler, Kalpathy S Krishnamoorthy, Christopher J Hartnick
Chronic aspiration poses a major health risk to the pediatric population. We describe four cases in which work up for chronic aspiration with a brain MRI revealed a Chiari I malformation, a poorly described etiology of pediatric aspiration. All patients had at least one non-specific neurologic symptom but had swallow studies more characteristic of an anatomic than a neurologic etiology. Patients were referred to neurosurgery and underwent posterior fossa decompression with symptom improvement. A high index of suspicion for Chiari malformation should be maintained when the standard work up for aspiration is non-diagnostic, particularly when non-specific neurologic symptoms are present...
September 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27496007/a-case-of-vertebral-artery-aneurysm-presenting-with-dysphagia
#17
Hiroyuki Morishita, Satoshi Nakamura, Naoki Toma, Yoshinari Nakatsuka, Kazuhiko Takeuchi
Here, we report a case of vertebral artery aneurysm causing dysphagia in a 56-year-old man who had no remarkable past history. Two months before the first visit, he developed posterior neck pain followed by difficulty swallowing 1 month later. He was referred to our clinic because of gradually worsening dysphagia. Physical examination showed paralysis of cranial nerves IX, X, and XII; therefore, he was hospitalized. Because enhanced CT and MRI showed a partially thrombosed right vertebral artery aneurysm, he was transferred to the care of the Department of Neurosurgery...
August 2, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/27487887/an-integrated-model-driven-method-for-in-treatment-upper-airway-motion-tracking-using-cine-mri-in-head-and-neck-radiation-therapy
#18
Hua Li, Hsin-Chen Chen, Steven Dolly, Harold Li, Benjamin Fischer-Valuck, James Victoria, James Dempsey, Su Ruan, Mark Anastasio, Thomas Mazur, Michael Gach, Rojano Kashani, Olga Green, Vivian Rodriguez, Hiram Gay, Wade Thorstad, Sasa Mutic
PURPOSE: For the first time, MRI-guided radiation therapy systems can acquire cine images to dynamically monitor in-treatment internal organ motion. However, the complex head and neck (H&N) structures and low-contrast/resolution of on-board cine MRI images make automatic motion tracking a very challenging task. In this study, the authors proposed an integrated model-driven method to automatically track the in-treatment motion of the H&N upper airway, a complex and highly deformable region wherein internal motion often occurs in an either voluntary or involuntary manner, from cine MRI images for the analysis of H&N motion patterns...
August 2016: Medical Physics
https://www.readbyqxmd.com/read/27328011/optimal-contrast-enhancement-liquid-for-dynamic-mri-of-swallowing
#19
M Ohkubo, T Higaki, K Nishikawa, M Otonari-Yamamoto, T Sugiyama, R Ishida, M Wakoh
Several dynamic magnetic resonance imaging (MRI) techniques to observe swallowing and their parameters have been reported. Although these studies used several contrast enhancement liquids, no studies were conducted to investigate the most suitable liquids. The purpose of this study was to identify the optimal contrast enhancement liquid for dynamic MRI of swallowing. MRI was performed using a new sequence consisting of true fast imaging with steady-state precession, generalised auto-calibrating partially parallel acquisition and a keyhole imaging technique...
September 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/27172522/oesophageal-foreign-bodies-from-diagnostic-challenge-to-therapeutic-dilemma
#20
Dragoş Predescu, Irina Predescu, Codruţ Sarafoleanu, Silviu Constantinoiu
Ingestion of foreign bodies, common in the emergency services, remains a challenge for physicians despite preventive measures and technical progress due to the frequency and possible complications, serious complications that can darken vital prognosis or may be a source of remote morbidity. Clinical experience at "St. Mary" Hospital included, between 2000-2015, 39 patients diagnosed with FB ingestion, of which 26 fixed in the oesophagus, with the remaining 13 having spontaneously progressed along the digestive tract (5 recovered from the stomach, 6 naturally evacuated, and 2 cases with colic perforation)...
March 2016: Chirurgia
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