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https://www.readbyqxmd.com/read/29777900/material-basis-research-for-huangqi-jianzhong-tang-against-chronic-atrophic-gastritis-rats-through-integration-of-urinary-metabonomics-and-systemsdock
#1
Yuetao Liu, Wenqian Xu, GuoHong Wang, Xuemei Qin
ETHNOPHARMACOLOGICAL RELEVANCE: Huangqi Jianzhong Tang (HQJZ), a celebrated traditional Chinese medicine (TCM), is commonly used for treatment of chronic atrophic gastritis (CAG) in China. AIM OF THE STUDY: We aimed to screen out the material basis of HQJZ against CAG. MATERIALS AND METHODS: CAG rat model was constructed by alternant administrations of ammonia solution and sodium deoxycholate, and the hunger disorder method. Body weight, biochemical indexes and histopathological exam were used to evaluate the efficacy of HQJZ...
May 16, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29775226/moxibustion-for-cephalic-version-of-breech-presentation
#2
REVIEW
Judith M Schlaeger, Cynthia L Stoffel, Jeanie L Bussell, Hui Yan Cai, Miho Takayama, Hiroyoshi Yajima, Nobuari Takakura
Moxibustion, a form of traditional Chinese medicine (TCM), is the burning of the herb moxa (Folium Artemisiae argyi or mugwort) over acupuncture points. It is often used in China to facilitate cephalic version of breech presentation. This article reviews the history, philosophy, therapeutic use, possible mechanisms of action, and literature pertaining to its use for this indication. For moxibustion, moxa can be rolled into stick form, placed directly on the skin, or placed on an acupuncture needle and ignited to warm acupuncture points...
May 18, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29770277/a-strategy-to-find-novel-candidate-anti-alzheimer-s-disease-drugs-by-constructing-interaction-networks-between-drug-targets-and-natural-compounds-in-medical-plants
#3
Bi-Wen Chen, Wen-Xing Li, Guang-Hui Wang, Gong-Hua Li, Jia-Qian Liu, Jun-Juan Zheng, Qian Wang, Hui-Juan Li, Shao-Xing Dai, Jing-Fei Huang
Background: Alzheimer' disease (AD) is an ultimately fatal degenerative brain disorder that has an increasingly large burden on health and social care systems. There are only five drugs for AD on the market, and no new effective medicines have been discovered for many years. Chinese medicinal plants have been used to treat diseases for thousands of years, and screening herbal remedies is a way to develop new drugs. Methods: We used molecular docking to screen 30,438 compounds from Traditional Chinese Medicine (TCM) against a comprehensive list of AD target proteins...
2018: PeerJ
https://www.readbyqxmd.com/read/29765502/the-phenolic-components-of-gastrodia-elata-improve-prognosis-in-rats-after-cerebral-ischemia-reperfusion-by-enhancing-the-endogenous-antioxidant-mechanisms
#4
Anhuan Shi, Jianming Xiang, Fangyan He, Yanping Zhu, Gongbei Zhu, Yuhan Lin, Ningna Zhou
Pharmacological or spontaneous thrombolysis in ischemic stroke triggers an outbreak of reactive oxygen species and results in neuron death. Nrf2-mediated antioxidation in cells has been proved as a pivotal target for neuroprotection. This research reports that phenolic components of Gastrodia elata Blume (PCGE), a traditional Chinese medicine, can alleviate the pathological lesions in the penumbra and hippocampus by increasing the survival of neurons and astrocytes and improve neurofunction and cognition after reperfusion in a rat model of middle cerebral artery occlusion...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29764877/efficacy-of-practising-tai-chi-for-older-people-with-mild-dementia-protocol-for-a-randomised-controlled-study
#5
Jihui Lyu, Wenjie Li, Xiangjiang Rong, Lian Wei, Nayan Huang, Mei Champ, Qian Xiong, Xueli Chen, Mo Li, Fangling Li
INTRODUCTION: Many studies suggest that Tai Chi exercise is a safe and appropriate mind-body exercise for older people and effectively slows down age-related cognitive decline. A set of bespoke Tai Chi exercise named 'Cognition Protecting Tai Chi' (CPT) has been created for older people with cognitive impairments by the research team of geriatricians, neurologists, rehabilitation specialists, experts of sports medicine and experienced practitioners of traditional Chinese medicine. This trial is designed to evaluate its effects on cognitive function, behaviour/moods, risk of falls and activities of daily living of the participants with mild dementia...
May 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29758520/probing-the-transcriptome-of-aconitum-carmichaelii-reveals-the-candidate-genes-associated-with-the-biosynthesis-of-the-toxic-aconitine-type-c-19-diterpenoid-alkaloids
#6
Dake Zhao, Yong Shen, Yana Shi, Xingqiao Shi, Qin Qiao, Shuhui Zi, Erqiang Zhao, Diqiu Yu, Edward J Kennelly
Aconitum carmichaelii has long been used as a traditional Chinese medicine, and its processed lateral roots are known commonly as fuzi. Aconitine-type C19 -diterpenoid alkaloids accumulating in the lateral roots are some of the main toxicants of this species, yet their biosynthesis remains largely unresolved. As a first step towards understanding the biosynthesis of aconitine-type C19 -diterpenoid alkaloids, we performed de novo transcriptome assembly and analysis of rootstocks and leaf tissues of Aconitum carmichaelii by next-generation sequencing...
May 11, 2018: Phytochemistry
https://www.readbyqxmd.com/read/29755358/therapeutic-angiogenesis-of-chinese-herbal-medicines-in-ischemic-heart-disease-a-review
#7
REVIEW
Dongqing Guo, Colin E Murdoch, Tianhua Liu, Jia Qu, Shihong Jiao, Yong Wang, Wei Wang, Xing Chen
Ischemic heart disease (IHD) is one of the primary causes of death around the world. Therapeutic angiogenesis is a promising innovative approach for treating IHD, improving cardiac function by promoting blood perfusion to the ischemic myocardium. This treatment is especially important for targeting patients that are unable to undergo angioplasty or bypass surgery. Chinese herbal medicines have been used for more than 2,500 years and they play an important role alongside contemporary medicines in China. Growing evidence in animal models show Chinese herbal medicines can provide therapeutic effect on IHD by targeting angiogenesis...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29752731/metabolomic-comparison-between-wild-ophiocordyceps-sinensis-and-artificial-cultured-cordyceps-militaris
#8
Lin Chen, Yuetao Liu, Qingfeng Guo, Qingxia Zheng, Wancun Zhang
In this study, a systematic research on the metabolome differences between wild Ophiocordyceps sinensis (O. sinensis) and artificial cultured Cordyceps militaris (C. militaris) was conducted using liquid chromatography-mass spectrometry. Principal components analysis (PCA) and Orthogonal projection on latent structure-discriminant analysis (OPLS-DA) results showed that C. militaris grown on solid rice medium (R-CM) and C. militaris grown on tussah pupa (T-CM) evidently separated and individually separated from wild O...
May 11, 2018: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29752613/immune-homeostasis-effects-of-chinese-herbal-formulae-and-herb-derived-compounds-on-allergic-asthma-in-different-experimental-models
#9
REVIEW
Lu Liu, Lin-Peng Wang, Shan He, Yan Ma
Allergic asthma is thought to arise from an imbalance of immune regulation, which is characterized by the production of large quantities of IgE antibodies by B cells and a decrease of the interferon-γ/interleukin-4 (Th1/Th2) ratio. Certain immunomodulatory components and Chinese herbal formulae have been used in traditional herbal medicine for thousands of years. However, there are few studies performing evidence-based Chinese medicine (CM) research on the mechanisms and effificacy of these drugs in allergic asthma...
May 2018: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29751724/-textual-research-on-origin-and-genuine-of-lilii-bulbus
#10
Chang-Hua Wang, Shu Shu, Fu-Jun Yin, Ji-Feng Zhao, Zhi-Wei Zhang, Xiang Liu, Zhi-Lai Zhan
Lilii Bulbus, which comes from many medicinal plants,is a frequently-used traditional Chinese medicine,the records in previous herbal literatures of it's origin and quality were inconstant. To trace back it's sources, we conducted a systematical study on it's origin and quality by textual research and investigation in this paper,The result showed that the origins of Lilii Bulbus are mainly source from white-flowers, red-yellow-flowers and red-flowers of Lilium, L. brownii var. viridulum, which were believed authentic or good quality in all previous herbal literatures,and L...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29751723/-study-on-medication-laws-of-tibetan-medicine-in-treatment-of-plateau-disease-based-on-data-mining-technology
#11
Huan Liu, Cai-Yun Zhao, Wen Zhang, Yi Zhang, Jia Nie
Traditional Chinese medicine inheritance support system (TCMISS, V2.5) was used in this study to analyze the common medicines, frequency of medicine combination, core herbal combinations and new prescriptions for the treatment of plateau disease from the Four-Volume Medical Code, Mannose Herbal Mirror and other related books. TCMISS V2.5 software was used to construct the database of drug treatment for plateau disease. The frequency analysis and association rules apriori algorithm, improved mutual information method and other data mining methods were used to explore the law of drug compatibility...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29751698/-pharmacological-effect-of-schisandrae-chinensis-fructus-and-relative-active-components-on-cardiovascular-and-cerebrovascular-diseases
#12
Min-Yu Zhang, Hong-Wei Wu, Li-Ping Xu, Hong-Jun Yang
Cardiovascular and cerebrovascular diseases (CCDs) are the primary causes of death in Chinese adults. With the increase in morbidity and mortality rates and the decrease in the age of onset, CCD becomes a very natural target for traditional Chinese medicine. Schisandrae Chinensis Fructus (SCF) is the dry ripe fruit of Schisandra chinensis (Turcz.) Baill., which features a sweet and sour taste and the effects of calming the heart and tranquilizing the mind. It is mainly used for treatment of dysphoria and palpitation, insomnia and dreamful sleep due to the lack of spirit preservation...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29751697/-emotional-stress-induced-shanghuo-syndrome-increases-disease-susceptibility
#13
Si-Rui Zhu, Xiang Luo, Yi-Fang Li, Kurihara Hiroshi, Rong-Rong He
Shanghuo(excessive internal heat) is a special organic state based on the concept of traditional Chinese medicine(TCM), commonly known as the abnormal heating syndrome of body in folks. With the acceleration of modern life rhythm and the increase of the social competition pressure, emotional stress has become an important cause for the spread of Shanghuo symptoms. What's more, Shanghuo can impact the body physiological functions to cause the onset, recurrence and progression of common diseases, harming the health of the body...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29751696/-research-of-pollution-free-and-precision-cultivation-system-of-chinese-herbal-medicines
#14
Shi-Lin Chen, Lin-Lin Dong, Qiao-Sheng Guo, Jian-He Wei, Xi-Wen Li, Gang Li, Qi Li, Yu-de Liu, Si-Jing Liu, Hong Xu, Yu-Qi Yu, Jie Wu, Chong-Heng Liang
The issues of disordering production and non-standard pesticide application are common in the production of Chinese herbal medicines. Aimed to above problems, research groups built the pollution-free and precision cultivation system of medicinal plants. This system mainly included the precise site selection of medicinal plants based on the GIS technology, modern omics-assisted breeding, metagenomics guiding the soil complex improvement, and the precise field management based on rational application of fertilizer and comprehensive control of disease...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29751647/rapid-characterization-of-components-in-bolbostemma-paniculatum-by-uplc-ltq-orbitrap-ms-n-analysis-and-multivariate-statistical-analysis-for-herb-discrimination
#15
Yanling Zeng, Yang Lu, Zhao Chen, Jiawei Tan, Jie Bai, Pengyue Li, Zhixin Wang, Shouying Du
Bolbostemma paniculatum is a traditional Chinese medicine (TCM) showed various therapeutic effects. Owing to its complex chemical composition, few investigations have acquired a comprehensive cognition for the chemical profiles of this herb and explicated the differences between samples collected from different places. In this study, a strategy based on UPLC tandem LTQ-Orbitrap MSn was established for characterizing chemical components of B. paniculatum . Through a systematic identification strategy, a total of 60 components in B...
May 11, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29751596/network-medicine-for-alzheimer-s-disease-and-traditional-chinese-medicine
#16
REVIEW
Juliet T Jarrell, Li Gao, David S Cohen, Xudong Huang
Alzheimer’s Disease (AD) is a neurodegenerative condition that currently has no known cure. The principles of the expanding field of network medicine (NM) have recently been applied to AD research. The main principle of NM proposes that diseases are much more complicated than one mutation in one gene, and incorporate different genes, connections between genes, and pathways that may include multiple diseases to create full scale disease networks. AD research findings as a result of the application of NM principles have suggested that functional network connectivity, myelination, myeloid cells, and genes and pathways may play an integral role in AD progression, and may be integral to the search for a cure...
May 11, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29751517/bibliometric-analysis-of-traditional-chinese-medicine-scientific-production-between-1982-and-2016-indexed-in-pubmed
#17
Ricardo Consentino, Maria João Santos, Luís Carlos Matos, Jorge Pereira Machado
Background: Traditional Chinese medicine (TCM) may be understood as a system of sensations and findings designed to establish the functional vegetative state of the body. This state may be treated by several therapeutic methods such as acupuncture, Chinese pharmacotherapy, dietetics, Tuina , and Qigong . Nowadays, as a result of several evidence-based reported beneficial effects over specific pathological conditions, there is an increasing tendency to integrate some of these practices in Western medicine. The main goal of this study was to perform a bibliometric analysis of TCM scientific production between 1982 and 2016 indexed in PubMed, by analyzing several parameters including time and location distribution, publication quality, experimental design, and treatment methods...
May 3, 2018: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29751125/anti-inflammatory-activities-and-potential-mechanisms-of-phenolic-acids-isolated-from-salvia-miltiorrhiza-f-alba-roots-in-thp-1-macrophages
#18
Haimei Liu, Shuli Ma, Hongrui Xia, Hongxiang Lou, Faliang Zhu, Longru Sun
ETHNOPHARMACOLOGICAL RELEVANCE: The roots of Salvia miltiorrhiza f. alba (Lamiaceae) (RSMA) are used as the Danshen, a traditional Chinese medicine, to treat the vascular diseases at local clinics, especially for the remedy of thromboangiitis obliterans (TAO) more than 100 years. Phenolic acids are one of the major effective constituents of RSMA, and some studies have linked phenolic acids with anti-inflammatory functions. AIM OF THE STUDY: The purpose of this research was to isolate phenolic acids from RSMA and investigate their anti-inflammatory effects and potential mechanisms...
May 8, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29750635/mechanism-research-of-bu-shen-huo-xue-formula-against-renal-fibrosis-in-rats-with-5-6-nephrectomy-via-e-cadherin-%C3%AE-sma-and-tgf-%C3%AE-1
#19
Jian-Rao Lu, Hai-Yan Han, Jing Hu, Chuan-Fu Zhang, Jie Chen, Xiu-Feng Chen, Xin-Hua Wang, Rong-Hua Pan
OBJECTIVE: Renal fibrosis generally results in renal failure during the end stage of chronic renal diseases. There are many cell factors including E-cadherin, α-SMA, and TGF-β1 influencing deposition of extracellular matrix and leading to renal fibrosis. As the most important and widely-used therapy for various diseases in China for thousands of years, traditional Chinese medicine (TCM) provides a novel treatment for renal fibrosis. For clinical application, we explore the effect of Bu-Shen-Huo-Xue formula (BSHX), a traditional Chinese herbal formula, on E-cadherin and α-SMA in rats with 5/6 nephrectomy...
May 11, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29747718/what-has-traditional-chinese-medicine-delivered-for-modern-medicine
#20
Jigang Wang, Yin-Kwan Wong, Fulong Liao
The field of Traditional Chinese Medicine (TCM) represents a vast and largely untapped resource for modern medicine. Exemplified by the success of the antimalarial artemisinin, the recent years have seen a rapid increase in the understanding and application of TCM-derived herbs and formulations for evidence-based therapy. In this review, we summarise and discuss the developmental history, clinical background and molecular basis of an action for several representative TCM-derived medicines, including artemisinin, arsenic trioxide, berberine and Salvia miltiorrhiza or Danshen...
May 11, 2018: Expert Reviews in Molecular Medicine
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