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https://www.readbyqxmd.com/read/29331744/urinary-metabolomics-study-the-mechanism-of-taohong-siwu-decoction-intervention-in-acute-blood-stasis-model-rats-based-on-liquid-chromatography-coupled-to-quadrupole-time-of-flight-mass-spectrometry
#1
Xiaosong Zhang, Pengling Li, Yongli Hua, Peng Ji, Wanling Yao, Qi Ma, Ziwen Yuan, Yanqiao Wen, Chaoxue Yang, Yanming Wei
Taohong Siwu Decoction (TSD) is a classic prescription in traditional Chinese medicine and is widely used to promote blood circulation to remove blood stasis. However, the effect mechanisms are not yet well understood. Here, a urinary metabolomic approach based on liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (LC/Q-TOF-MS) was conducted to explore the changes in the endogenous metabolites and to assess the integral efficacy of TSD on acute blood stasis model rats. Then, parameters for hemorheology and coagulation functions were detected...
January 2, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29330687/evaluation-of-the-mitochondria-related-redox-and-bioenergetics-effects-of-gastrodin-in-sh-sy5y-cells-exposed-to-hydrogen-peroxide
#2
Marcos Roberto de Oliveira, Flávia Bittencourt Brasil, Cristina Ribas Fürstenau
Mitochondrion is the main site of ATP production in animal cells and also orchestrates signaling pathways associated with cell survival and death. Mitochondrial dysfunction has been linked to bioenergetics and redox impairment in human diseases, such as neurodegeneration and cardiovascular disease. Protective agents able to attenuate mitochondrial impairment are of pharmacological interest. Gastrodin (GAS; 4-hydroxybenzyl alcohol 4-O-beta-D-glucoside) is a phenolic glucoside obtained from the Chinese herbal medicine Gastrodia elata Blume and exhibits antioxidant, anti-inflammatory, and antiapoptotic effects in several cell types...
January 12, 2018: Journal of Molecular Neuroscience: MN
https://www.readbyqxmd.com/read/29327548/-research-of-tcm-synthetic-rehabilitation-on-the-recovery-of-wrist-joint-after-distal-radius-fractures
#3
Yong Zhao, Qing-Qing Dong, Wei-Kai Qin, An Yan, Kuan Zhang, Guo-Dong Zhao, Gang Wang, Jin-Chao Geng, Zhan-Feng Wang, Ze-Ming Lu
OBJECTIVE: To evaluate efficacy and advantages of the Traditional Chinese Medicine (TCM) synthetic rehabilitation therapy in the treatment of wrist dysfunction after distal radius fractures. METHODS: From May 2014 to October 2015, 72 patients with distal radius fracture meeting standards were treated using central randomization system for clinical research. All the patients were divided into two groups: 36 patients in test group and 36 in control group. Sixty-nine cases were finished treatment and followed up in the end...
January 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29320646/transfer-of-fresh-versus-frozen-embryos-in-ovulatory-women
#4
Yuhua Shi, Yun Sun, Cuifang Hao, Heping Zhang, Daimin Wei, Yunshan Zhang, Yimin Zhu, Xiaohui Deng, Xiujuan Qi, Hong Li, Xiang Ma, Haiqin Ren, Yaqin Wang, Dan Zhang, Bo Wang, Fenghua Liu, Qiongfang Wu, Ze Wang, Haiyan Bai, Yuan Li, Yi Zhou, Mei Sun, Hong Liu, Jing Li, Lin Zhang, Xiaoli Chen, Songying Zhang, Xiaoxi Sun, Richard S Legro, Zi-Jiang Chen
BACKGROUND: Elective frozen-embryo transfer has been shown to result in a higher live-birth rate than fresh-embryo transfer among anovulatory women with the polycystic ovary syndrome. It is uncertain whether frozen-embryo transfer increases live-birth rates among ovulatory women with infertility. METHODS: In this multicenter, randomized trial, we randomly assigned 2157 women who were undergoing their first in vitro fertilization cycle to undergo either fresh-embryo transfer or embryo cryopreservation followed by frozen-embryo transfer...
January 11, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29318840/-application-of-remote-sensing-and-gis-in-study-of-suitability-distribution-of-swertia-mussotii-a-tibetan-medicine-in-sichuan-province
#5
Yong-Bo Dong, Yao Luo, Cong Zhu, Wen-Fu Peng, Xin-Liang Xu, Qing-Mao Fang
Swertia mussotii is a kind of rare medicinal materials, the relevant researches are mainly concentrated on its medicinal efficacy and medicinal value till now, researches of adaptive distribution by applying remote sensing and GIS are relatively less. This study is to analyze the adaptive distribution of S.mussotii in Sichuan province by applying remote sensing and GIS technology, and provide scientific basis for the protection and development of wild resources, artificial cultivation and adjustment of Chinese medicine industrial distribution in Sichuan province...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318837/-study-on-distribution-division-of-codonopsis-radix
#6
Xiao-Jun Wu, Xiao-Bo Zhang, Lan-Ping Guo, Yi Yu, Lu-Qi Huang
This paper is aimed to clarify the distribution of Codonopsis Radix in China and search the main ecological factors that affect the suitability distribution. Through literature reading, National Specimen Information Infrastructure researching, field investigation and general survey of Chinese medicine resources, the distribution information was acquired. The MaxEnt model and ArcGIS technology were applied to analyze the main environmental factors influencing the suitability of Codonopsis Radix with integrated 55 environmental factors...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318824/-design-and-implementation-of-data-checking-system-for-chinese-materia-medica-resources-survey
#7
Hui Wang, Xiao-Bo Zhang, Xiao-Guang Ge, Yan Jin, Zhi-Xian Jing, Yuan-Hua Qi, Ling Wang, Yu-Ping Zhao, Wei Wang, Lan-Ping Guo, Lu-Qi Huang
The Chinese material medica resources (CMMR) national survey information management system has collected a large amount of data. To help dealing with data recheck, reduce the work of inside, improve the recheck of survey data from provincial and county level, National Resource Center for Chinese Materia Medical has designed a data checking system for Chinese material medica resources survey based on J2EE technology, Java language, Oracle data base in accordance with the SOA framework. It includes single data check, check score, content manage, check the survey data census data with manual checking and automatic checking about census implementation plan, key research information, general survey information, cultivation of medicinal materials information, germplasm resources information the medicine information, market research information, traditional knowledge information, specimen information of this 9 aspects 20 class 175 indicators in two aspects of the quantity and quality...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318822/-design-and-implementation-of-data-reporting-system-for-chinese-materia-medica-resources-survey
#8
Hui Wang, Xiao-Bo Zhang, Xiao-Guang Ge, Zhi-Xian Jing, Ling Wang, Yu-Ping Zhao, Lan-Ping Guo, Lu-Qi Huang
The collection, summary and sharing of all kinds of survey data are one of the main tasks and achievements in the national census of Chinese materia medica resources organized and implemented by the State Administration of Traditional Chinese Medicine. It is a key link in the implementation of the national census of Chinese materia medica resources. Based on the client / server architecture, the data reporting system for Chinese materia medica resources survey has been established for reporting system application model of geospatial data service based on Web implementation, through the SOA framework, to achieve the data collection summary of the seven aspects of the local data configuration, data reporting, data verification, data reporting, PDA data import and export, APP data import, track instrument data import...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29318814/-information-work-of-national-census-of-traditional-chinese-medicine-resources
#9
Lu-Qi Huang, Xiao-Bo Zhang
In order to promote the protection, development and rational utilization on traditional Chinese medicine resources (TCM resoueces), the State Administration of Traditional Chinese Medicine is organizing and implementing the fourth national survey on TCM resources. Informatization is the core for this survey and is also one of the main innovative points which transcend the previous three surveys. The extensive application on informatization technology has not only improved the work efficiency of the survey, but also expanded the new development directions of TCM resources research...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29316796/scutellaria-baicalensis-and-cancer-treatment-recent-progress-and-perspectives-in-biomedical-and-clinical-studies
#10
Chien-Shan Cheng, Jie Chen, Hor-Yue Tan, Ning Wang, Zhen Chen, Yibin Feng
Scutellaria baicalensis (Huangqin in Chinese) is a major traditional Chinese medicine (TCM) herb, which has a long history of use in the treatment of a variety of symptoms correlated with cancer. In the past decade, the potential of S. baicalensis and single compounds derived from it as anticancer agents targeting various pathways has received extensive research attention. Specifically, the proliferation and metastases inhibiting properties of the single compounds in cancer have been studied; however, the underlying mechanisms remain unclear...
January 9, 2018: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/29311532/the-formation-of-the-military-medical-system-of-the-korean-people-s-army-and-the-military-medical-officer
#11
Seonho Kim
The military medical system of the Korean People's Army (KPA) first appeared in August 1946 when a central military hospita was established at the headquarters. Inside the KPA, the military medical and veteran services were first established in February 1948. The military medical officers of the KPA were those who were initially engaged in North Korea's health care sector. Most of the early military medical officers were those who had been trained in the Japanese medical system before liberation and were surgeons...
December 2017: Ŭi Sahak
https://www.readbyqxmd.com/read/29295501/the-herb-drug-pharmacokinetic-interaction-of-5-fluorouracil-and-its-metabolite-5-fluoro-5-6-dihydrouracil-with-a-traditional-chinese-medicine-in-rats
#12
Ju-Han Liu, Yung-Yi Cheng, Chen-Hsi Hsieh, Tung-Hu Tsai
BACKGROUND: Xiang-Sha-Liu-Jun-Zi-Tang (XSLJZT) is the most common traditional formula given to colorectal and breast cancer patients in Taiwan, according to a statistical study of the National Health Insurance Research Database. 5-Fluorouracil (5-FU) is widely used as the first line of treatment for colorectal cancer. Thus, the aim of study is to investigate the pharmacokinetic interaction of XSLJZT and 5-FU. METHODS: To investigate the herb-drug interaction of XSLJZT with 5-FU as well as its metabolite 5-fluoro-5,6-dihydrouracil (5-FDHU) using pharmacokinetics, a high-performance liquid chromatography (HPLC) system coupled with a photodiode array detector was developed to monitor 5-FU and 5-FDHU levels in rat blood...
December 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29291006/the-application-of-precis-2-ratings-in-randomized-controlled-trials-of-chinese-herbal-medicine
#13
Liming Lu, Li Zhou, Jing Dong, Yu Xiang, Zehuai Wen
This study tests the feasibility of applying the pragmatic-explanatory continuum indicator summary (version "PRECIS-2") tool to randomized controlled trials of Chinese herbal medicine. A search was conducted to identify potentially eligible randomized controlled trials. Using the PRECIS-2 tool, assessment of trials was performed independently by 2 evaluators using a scale of 1-5 for each criterion (1 = maximal efficacy, 5 = maximal effectiveness). A total of 7,166 reports were retrieved from databases and 159 were included in the full text...
December 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/29283218/identifying-the-genotypes-of-hepatitis-b-virus-hbv-with-dna-origami-label
#14
Ke Liu, Dun Pan, Yanqin Wen, Honglu Zhang, Jie Chao, Lihua Wang, Shiping Song, Chunhai Fan, Yongyong Shi
The hepatitis B virus (HBV) genotyping may profoundly affect the accurate diagnosis and antiviral treatment of viral hepatitis. Existing genotyping methods such as serological, immunological, or molecular testing are still suffered from substandard specificity and low sensitivity in laboratory or clinical application. In a previous study, a set of high-efficiency hybridizable DNA origami-based shape ID probes to target the templates through which genetic variation could be determined in an ultrahigh resolution of atomic force microscopy (AFM) nanomechanical imaging are established...
December 28, 2017: Small
https://www.readbyqxmd.com/read/29281497/poly-drug-use-of-prescription-medicine-among-people-with-opioid-use-disorder-in-china-a-systematic-review-and-meta-analysis
#15
Tongyu Wang, Jun Ma, Rujia Wang, Zhimin Liu, Jie Shi, Lin Lu, Yanping Bao
BACKGROUND: Opioid use disorder (OUD) causes substantial public health and social problems worldwide. Poly-drug use is common in people with OUD and increases morbidity and mortality. Investigation of the patterns and characteristics of poly-drug use of prescription medicine among opioid users is needed to develop appropriate prevention and intervention strategies. OBJECTIVES: To estimate the prevalence of poly-drug use of prescription medicine among people with OUD in China using meta-analysis...
December 27, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/29278723/single-nucleotide-polymorphisms-of-microrna-in-cardiovascular-diseases
#16
REVIEW
Kamna Srivastava, Kirti Tyagi
Despite the advances in medicine and in science of diagnosis, cardiovascular diseases (CVD) remain the number one cause of morbidity and mortality worldwide. Apart from the modifiable risk factors, genetic factors are believed to also influence the outcome of this umbrella of diseases. Under the genetic factors, miRNA polymorphisms, namely miR-146a (rs2910164), miR-196 (rs11614913) and miR-499 (rs3746444), have become an important tool to study the mechanism that underlie the pathogenesis of this disease. In this review, we analyze the advances made through various research studies and the evidence provided by them in the area of miRNA polymorphisms by comparing the allelic frequencies and genotyping patterns...
December 24, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29276207/effects-of-antrodia-camphorata-and-panax-ginseng-supplementation-on-anti-fatigue-properties-in-mice
#17
Chien-Yu Hsiao, Yi-Ju Hsu, Yu-Tang Tung, Mon-Chien Lee, Chi-Chang Huang, City C Hsieh
Antrodia camphorata and Panax ginseng are well-known medicinal plants in Taiwan folk and traditional Chinese medicine, which have been reported for multifunctional bioactivities. However, there is limited evidence that a fixed combination formula of these two plant extracts is effective for the exercise improvement or anti-fatigue. We aimed to evaluate the potential beneficial effects of the mix formulation of these two herbal medicines (AG formulation) on fatigue and ergogenic functions following physiological challenge...
December 25, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29259982/pharmacokinetics-tissue-distribution-and-metabolism-study-of-icariin-in-rat
#18
Shunjun Xu, Jiejing Yu, Jingjing Zhan, Liu Yang, Longgang Guo, Yijuan Xu
Icariin is one of the predominant flavonoids contained in Herba Epimedii (Yin-yang-huo in Chinese), a well-known Chinese medicine for the treatment of cancers and immune system diseases. Although Herba Epimedii has been widely used in China and there are so many and various research reports on the herbal drug and its main flavones, very limited data is available on the tissue distribution and biotransformation of icariin. In the present study, a liquid chromatographic method combined with electrospray ionization tandem mass spectrometry was developed to quantify the concentration of icariin in rat plasma and various tissues collected at different time points after oral administration of the total flavonoid extract of Herba Epimedii at a dose of 0...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29259640/effectiveness-and-safety-of-the-combination-of-the-traditional-chinese-medicine-prescription-jade-screen-and-desloratadine-in-the-treatment-of-chronic-urticaria-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#19
REVIEW
Shao-Fei Yuan, Jing-Zhi Guan, Yong Hao, Jian-Yuan Chai, Feng-Li Gao, Su-Qin Shi, Jian-Xin Wang, Jin He, Ji-Hai Shi
Objective: The aim of this study is to systematically evaluate the clinical efficacy and safety of the traditional Chinese medicine prescription Jade Screen combined with desloratadine in the treatment of chronic urticaria. Methods: Two researchers independently conducted literature searches. The extracted data were analyzed using Rev Man 5.2.3 software. The established retrieval time range of the various databases was up to 15 March, 2017. Results: Sixteen randomized controlled trials were included in this study...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29258255/structure-features-and-anti-gastric-ulcer-effects-of-inulin-type-fructan-cp-a-from-the-roots-of-codonopsis-pilosula-franch-nannf
#20
Jiankuan Li, Tao Wang, Zhichuan Zhu, Fengrong Yang, Lingya Cao, Jianping Gao
Radix Codonopsis has been used in traditional Chinese medicine for strengthening the immune system, improving poor gastrointestinal function, treating gastric ulcers and chronic gastritis and so on. In the present study, an inulin-type fructan CP-A was obtained from the roots of Codonopsis pilosula (Franch.) Nannf. and its structure was confirmed by MS and NMR as (2 → 1) linked-β-d-fructofuranose. The protective effects of CP-A against ethanol-induced acute gastric ulcer in rats were intensively investigated...
December 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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