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French medicine / research

G Aubertin, C Schröder, F Sevin, F Clouteau, M-D Lamblin, M-F Vecchierini
The French Society of Research and Sleep Medicine (SFRMS) organized a meeting on obstructive sleep apnea syndrome (OSAS) in children. A multidisciplinary group of specialists (pulmonologist, ENT surgeons, pediatricians, orofacial myofunctional therapists, neurophysiologists, and sleep specialists) reached a consensus on the value of isolated or clustered clinical symptoms and of questionnaires completed by parents in the clinical diagnosis and in assessing the severity of OSAS. Are clinical history with validated questionnaires and a rigorous physical examination sufficient to suspect OSAS, to appreciate its severity, and finally to confirm the diagnosis? Usually, a sleep recording of respiratory parameters remains mandatory for the diagnosis of OSAS to be made...
October 18, 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
D Resiere
Martinique was accepted as an associate member by the Council of Ministers of the Organization of Eastern Caribbean State since February 2015. This membership constitutes a major asset in bringing Martiniquais closer to the other Caribbean populations and should play a key role as it relates to regional cooperation especially in the domain of healthcare. Martinique and several Caribbean countries share common health issues such as; dengue, chikungunya virus, Zika Virus leptospirosis, snakebite, severe cardiovascular diseases (CVD), HTLV-1, sickle cell diseases and so on...
August 1, 2016: Médecine et Santé Tropicales
F Saillour-Glénisson, S Domecq, M Kret, M Sibe, J P Dumond, P Michel
BACKGROUND: Although many organizational culture questionnaires have been developed, there is a lack of any validated multidimensional questionnaire assessing organizational culture at hospital ward level and adapted to health care context. Facing the lack of an appropriate tool, a multidisciplinary team designed and validated a dimensional organizational culture questionnaire for healthcare settings to be administered at ward level. METHODS: A database of organizational culture items and themes was created after extensive literature review...
2016: BMC Health Services Research
Fabien Salesses, Paul Perez, Aline E Maillard, Julie Blanchard, Sabine Mallard, Laurence Bordenave
BACKGROUND: The recent spread of positron emission tomography-computed tomography (PET/CT) poses extremity dosimetry challenges. The question arose whether the radiation dose measured by the ring thermoluminescent dosimeter usually worn on the proximal phalanx (P1) of the index finger measures doses that are representative of the true doses received by the upper extremities of the operators. A prospective individual dosimetry study was performed in which the personal equivalent dose Hp (0...
December 2016: EJNMMI Physics
Jørgen V Grevsen, Hanne Kirkegaard, Edith Kruse, Poul R Kruse
The article series provides a written and pictorial account of the Danish pharmaceutical industry's products from their introduction until about 1950. Part 8 deals with products from Lundbeck. Lundbeck which today is known as a considerable international pharmaceutical company could in 2015 celebrate its 100 years' jubilee. Among the early Danish medicinal companies H. Lundbeck & Co. is in many ways an exception as the company was not originally established as a pharmaceutical company. Not until several years after the foundation the company began to import foreign ready-made medicinal products and later-on to manufacture these medicinal products in own factory and even later to do research and development of own innovative products...
2016: Theriaca
Carla Vaucher, Emilie Bovet, Theresa Bengough, Vincent Pidoux, Michèle Grossen, Francesco Panese, Bernard Burnand
BACKGROUND: Multiple barriers to knowledge translation in medicine have been identified (ranging from information overload to abstraction of models), leading to important implementation gaps. This study aimed at assessing the suggestions of practicing physicians for possible improvements of knowledge translation (KT) effectiveness into clinical practice. METHODS: We used a mixed methods design. French- German- and Italian-speaking general practitioners, psychiatrists, orthopaedic surgeons, cardiologists, and diabetologists practicing in Switzerland were interrogated through semi-structured interviews, focus group discussions, and an online survey...
2016: Health Research Policy and Systems
P Aubry, B-A Gaüzère
In 1498, the Portuguese crossed the Cape of Good Hope. It was not until the period of 1633 and 1666, dates of the founding, respectively, of the Compagnie de l'Orient and the Compagnie des Indes orientales, that the way was definitively opened for trade between France and India. Because so many sailors developed scurvy after voyages that lasted 4 to 5 months, the French settled on Bourbon Island (Réunion) and Ile de France (Mauritius), to provide them with medical care. Created in 1689 by Louis XIV, the Navy Health Service was responsible for health in the colonies until it was replaced in 1890 by the Colonial Health Service...
May 1, 2016: Médecine et Santé Tropicales
Nadia Benmoussa, Jennifer Kerner, Patrice Josset, Patrick Conan, Philippe Charlier
Joseph Gensoul was a pioneer of ENT surgery. In 1827, he performed the first total maxillectomy on 17-year-old boy. His work inspired many surgeons, who were previously unwilling to remove maxillary tumours. A paleopathological study performed in the Dupuytren museum allowed us to identify a skull from the early 19th century, with a large maxillar tumour. There were indications that this skull was operated according to Gensoul's technique. The aim of this study is to confirm that this patient had, in fact, received this surgical treatment...
July 4, 2016: European Archives of Oto-rhino-laryngology
Pacifique Irankunda, Laurie Heatherington
Best practices in global mental health stress the importance of understanding local values and beliefs. Research demonstrates that expectancies about the effectiveness of a given treatment significantly predicts outcome, beyond the treatment effect itself. To help inform the development of mental health interventions in Burundi, we studied expectancies about the effectiveness of four treatments: spiritual healing, traditional healing, medication, and selected evidence-based psychosocial treatments widely used in the US...
June 17, 2016: Transcultural Psychiatry
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
Hye-Min Lee
This article aims to investigate the shaping of knowledge and discourse on ginseng, especially among physicians and botanists, since its introduction to France from the 17th century until the early 18th century. In France, knowledge on herbal medicine, including that of ginseng, was shaped under the influence of the modern state's policy and institution: mercantilism and the Académie royale des sciences. The knowledge of herbal medicine developed as an important part of the mercantilist policy supported systematically by the Académie...
April 2016: Ŭi Sahak
Annie-Pierre Jonville-Béra, Michel Mallaret, Catherine Sgro
In 1976, the Regional Pharmacovigilance Centres were created in France to collect and analyze adverse drug reactions. Even if they have, to date, managed and transmitted more than 583,000 adverse drug reactions to the French and international health authorities, the missions of these university hospital structures supervised by clinical pharmacologists are not limited to this activity. They also provide a consulting and diagnostic aid for drug diseases. Their other main mission is information about drugs and their proper use for health professionals and patients on any matter relating to medicines...
September 2016: Thérapie
Emmanuel Delille
Henri Ellenberger (1905-1993) wrote the first French-language synthesis of transcultural psychiatry ("Ethno-psychiatrie") for the French Encyclopédie Médico-Chirurgicale in 1965. His work casts new light on the early development of transcultural psychiatry in relation to scientific communities and networks, particularly on the role of Georges Devereux (1908-1985). The Ellenberger archives offer the possibility of comparing published texts with archival ones to create a more nuanced account of the history of transcultural psychiatry, and notably of the psychological treatment of Native Americans...
June 2016: Transcultural Psychiatry
L Mische Lawson, J Cline, A French, N Ismael
Patients with various forms of cancer receiving blood and marrow transplant (BMT) treatment at an outpatient clinic develop chemotherapy-related symptoms and an increased desire to use complementary and alternative medicine in order to address these symptoms. Art-making offers an inexpensive way to pass time and relieve symptoms during long hours in treatment. Twenty-one BMT patients painted a tile and participated in research. Researchers used semi-structured interviews to understand patients' experiences with art-making...
May 16, 2016: European Journal of Cancer Care
Maureen French, Alexandra Albanese, Dana R Gossett
OBJECTIVE: To evaluate the effect of high-risk pregnancy status on antepartum contraceptive planning and postpartum use. METHODS: We performed a retrospective cohort study of women delivering at a university hospital during 2009-2010 who received prenatal care in the faculty or resident clinics. We defined high-risk status by Society for Maternal-Fetal Medicine guidelines. We abstracted contraceptive planning and postpartum administration from medical records and categorized these into World Health Organization tiers of contraceptive effectiveness...
August 2016: Contraception
Aurélie Mahalatchimy
Cell-based regenerative therapies are presented as being able to cure the diseases of the twenty-first century, especially those coming from the degeneration of the aging human body. But their specific nature based on biological materials raises particular challenging issues on how regulation should frame biomedical innovation for society's benefit regarding public health. The European Union (EU) supports the development of cell-based regenerative therapies that are medicinal products with a specific regulation providing their wide access to the European market for European patients...
2016: Medical Law Review
Raphael Toledano
August Hirt (1898-1945) was director of the Institute of Anatomy of the Reichsuniversität Strassburg from November 1941 to November 1944. During this period, he was involved in many criminal activities: mustard gas experiments on prisoners of KL Natzweiler-Struthof, creating a collection of Jewish skeletons by gassing 86 Jews from KL Auschwitz in the Struthof-Natzweiler gas chamber, and involvement in experiments on phosgene gas performed by Otto Bickenbach. Extensive literature exists on these crimes. However, there has been very little work completed on the so-called normal activity of the Institute of Anatomy of which he was head and in particular the question of deliveries of corpses...
May 2016: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
Jean-Marie Milleliri
He would have celebrated his 100th birthday in 2015, but finally, it doesn't matter, since by leaving his name to African meningitis belt, that isohyetal band in sub-Saharan Africa where epidemics of cerebrospinal meningitis are rife, Lapeyssonnie, the trailblazer at the end of his trail, has gone straight into the textbooks of tropical medicine. There was probably nothing he enjoyed more than wandering the lateritic paths and Sudano-Sahelian bush in that zone. His first job, in the Mossi country in Upper Volta that had not yet become Burkina Faso, was of course an initiation...
January 2016: Médecine et Santé Tropicales
Marie-Odile Habert, Sullivan Marie, Hugo Bertin, Moana Reynal, Jean-Baptiste Martini, Mamadou Diallo, Aurélie Kas, Régine Trébossen
BACKGROUND: CATI is a French initiative launched in 2010 to handle the neuroimaging of a large cohort of subjects recruited for an Alzheimer's research program called MEMENTO. This paper presents our test protocol and results obtained for the 22 PET centres (overall 13 different scanners) involved in the MEMENTO cohort. We determined acquisition parameters using phantom experiments prior to patient studies, with the aim of optimizing PET quantitative values to the highest possible per site, while reducing, if possible, variability across centres...
December 2016: EJNMMI Physics
Olaf H Klungel, Xavier Kurz, Mark C H de Groot, Raymond G Schlienger, Stephanie Tcherny-Lessenot, Lamiae Grimaldi, Luisa Ibáñez, Rolf H H Groenwold, Robert F Reynolds
PURPOSE: To assess the impact of a variety of methodological parameters on the association between six drug classes and five key adverse events in multiple databases. METHODS: The selection of Drug-Adverse Event pairs was based on public health impact, regulatory relevance, and the possibility to study a broad range of methodological issues. Common protocols and data analytical specifications were jointly developed and independently and blindly executed in different databases in Europe with replications in the same and different databases...
March 2016: Pharmacoepidemiology and Drug Safety
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