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Hip maturity

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https://www.readbyqxmd.com/read/29765930/effect-of-fennel-on-the-health-status-of-menopausal-women-a-systematic-and-meta-analysis
#1
Talat Khadivzadeh, Mona Najaf Najafi, Leila Kargarfard, Masumeh Ghazanfarpour, Fatemeh Rajab Dizavandi, Imaneh Khorsand
Objectives: The aim of the present study is the systematic and critical investigation of the effectiveness of fennel on the climacteric symptoms among menopausal females. Methods: A search of the trials studying the effect of fennel on menopausal females was conducted in 2017 using the MEDLINE and Scopus databases and the Cochrane Library with the following keywords: fennel, Foeniculum vulgare , and menopause. Results: Fennel combined with officinalis is more effective in the attenuating of sleep disorders compared to Citalopram...
April 2018: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/29747677/use-of-clinical-and-computed-tomography-findings-to-assess-long-term-unsatisfactory-outcome-after-femoral-head-and-neck-ostectomy-in-four-large-breed-dogs
#2
Ciprian Ober, Cosmin Pestean, Lucia Bel, Marian Taulescu, Joshua Milgram, Adrian Todor, Rodica Ungur, Mirela Leșu, Liviu Oana
Femoral head and neck ostectomy (FHNO) is a salvage surgical procedure intended to eliminate hip joint laxity associated pain in the immature dog, or pain due to secondary osteoarthritis in the mature dog. The outcome of the procedure is associated with the size of the dog but the cause of a generally poorer outcome in larger breeds has not been determined. The objective of this study was to assess the long-term results of FHNO associated with unsatisfactory functional outcome by means of clinical examination and computed tomography (CT) scanning...
May 10, 2018: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/29716892/human-proislet-peptide-promotes-pancreatic-progenitor-cells-to-ameliorate-diabetes-via-foxo1-menin-mediated-epigenetic-regulation
#3
Zongzhe Jiang, Diwen Shi, Yifan Tu, Jingjing Tian, Wenjian Zhang, Bowen Xing, Jihua Wang, Suhuan Liu, Jinning Lou, Jan-Åke Gustafsson, Xianxin Hua, Xiaosong Ma
In this study, we investigated how human proislet peptide (HIP) regulates differentiation of human fetus-derived pancreatic progenitor cells (HFPPCs), and explored the potential link between HIP signaling and the menin pathway, a key pathway that regulates differentiation of pancreatic islets. Our data showed that HIP promoted expression of pro-islet transcription factors (TFs) including PDX-1, MAFA and NKX6.1 as well as other maturation markers of β-cells such as insulin, GLUT2, KIR6.2, SUR1 and VDCC. Moreover, HIP increased insulin content, and promoted the ability of HFPPCs to normalize the blood glucose in diabetic mice...
May 1, 2018: Diabetes
https://www.readbyqxmd.com/read/29622494/evaluation-of-the-learning-curve-when-transitioning-from-posterolateral-to-direct-anterior-hip-arthroplasty-a-consecutive-series-of-1000-cases
#4
Andrea H Stone, Udai S Sibia, Ryan Atkinson, Timothy R Turner, Paul J King
BACKGROUND: The direct anterior approach (DAA) for primary hip replacement has been gaining more attention and widespread use in recent years. There are a number of published studies evaluating the learning curve when a surgeon changes technique; these studies typically look at complications during the initial cases. This study examines procedure and total operating room (OR) time along with all complications for a surgeon transitioning from the posterolateral approach (PA) to DAA. METHODS: A retrospective review of a single surgeon series of 1000 initial DAA procedures...
March 8, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29595056/live-cell-imaging-in-microfluidic-device-proves-resistance-to-oxygen-glucose-deprivation-in-human-induced-pluripotent-stem-cell-derived-cardiomyocytes
#5
Sebastian Martewicz, Giulia Gabrel, Marika Campesan, Marcella Canton, Fabio Di Lisa, Nicola Elvassore
Analyses of cellular responses to fast oxygen dynamics are challenging and require ad hoc technological solutions, especially when decoupling from liquid media composition is required. In this work, we present a microfluidic device specifically designed for culture analyses with high resolution and magnification objectives, providing full optical access to the cell culture chamber. This feature allows fluorescence-based assays, photoactivated surface chemistry, and live cell imaging under tightly controlled pO2 environments...
May 1, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29540184/analysis-of-human-sperm-dna-fragmentation-index-dfi-related-factors-a-report-of-1010-subfertile-men-in-china
#6
Jin-Chun Lu, Jun Jing, Li Chen, Yi-Feng Ge, Rui-Xiang Feng, Yuan-Jiao Liang, Bing Yao
BACKGROUND: Many factors may lead to sperm DNA damage. However, it is little known that the correlations of sperm DNA damage with obesity-associated markers, and reproductive hormones and lipids levels in serum and seminal plasma. METHODS: In our prospective study, a total of 1 010 subfertile men, aged from 18 to 50 years old, were enrolled from August 2012 through June 2015. Their obesity-associated markers, semen parameters, sperm acrosomal enzyme activity, seminal plasma biochemical markers, and reproductive hormones and lipids levels in serum and seminal plasma were detected...
March 14, 2018: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/29499808/improving-identification-and-diagnosis-of-hypertensive-patients-hiding-in-plain-sight-hips-in-health-centers
#7
Margaret Meador, Jerome A Osheroff, Benjamin Reisler
BACKGROUND: Hypertension is the most prevalent chronic condition diagnosed among patients served in the safety net in the United States; however, many safety-net patients with hypertension are not formally diagnosed and may remain untreated and at increased risk for cardiovascular events. Identifying undiagnosed hypertension using algorithmic logic programmed into clinical decision support (CDS) approaches is a promising practice but has not been broadly tested in the safety-net setting...
March 2018: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29465155/effects-of-physical-activity-on-sclerostin-concentrations
#8
Małgorzata Janik, Michał Stuss, Marta Michalska-Kasiczak, Anna Jegier, Ewa Sewerynek
Osteoporosis is a serious medical and socioeconomic problem of the 21st century. Mechanical load is a key regulator which controls bone formation and remodelling, with participation of osteocytes. Sclerostin is produced and released by mature osteocytes into bone surface, where it inhibits the conveyance of osteoblast proliferation and differentiation activating signals from mesenchymal cells, thus suppressing new bone formation. The goal of the study was an evaluation of the effects of a 12-week physical training programme on the levels of bone turnover markers [Sclerostin, Osteocalcin (OC), C-terminal telopeptide of type I collagen (β-CTX)] in blood serum of women with osteopenia...
February 21, 2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29460315/sealed-osteons-in-animals-and-humans-low-prevalence-and-lack-of-relationship-with-age
#9
John G Skedros, Tanner R Henrie, Madison S Doutré, Roy D Bloebaum
Sealed osteons are unusual variants of secondary osteons that have received little attention, especially in non-human bones. Sealed osteons are characterized by central canals that are plugged with bone tissue. As with other variants of secondary osteons (e.g. drifting, dumbbell, multi-canal), understanding how and why sealed osteons form can shed light on the mechanisms that regulate normal bone remodeling and how this process can be perturbed with aging and some diseases. In a recent microscopic evaluation of human tibiae obtained after traumatic amputations, 4-5% of the osteons were sealed...
May 2018: Journal of Anatomy
https://www.readbyqxmd.com/read/29456754/management-of-osteonecrosis-of-the-femoral-head-in-children-with-sickle-cell-disease-results-of-conservative-and-operative-treatments-at-skeletal-maturity
#10
C Mallet, A Abitan, C Vidal, L Holvoet, K Mazda, A-L Simon, B Ilharreborde
Purpose: Sickle cell disease (SCD) is the most common cause of femoral head osteonecrosis (ONFH) during childhood with an overall prevalence of 10%. In children, spontaneous revascularization can occur, as in Legg-Calve-Perthes disease. Consequently, the aim of treatment is to restore proper hip containment to prevent joint arthritis. This is the first study reporting long-term results at skeletal maturity of non-operative and surgical treatments for ONFH in SCD children. Methods: All children with ONFH due to SCD were retrospectively reviewed...
February 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29432264/longitudinal-growth-and-pqct-measures-in-hutterite-children-and-grandchildren-are-associated-with-prevalence-of-hip-or-knee-replacement-resulting-from-osteoarthritis-in-parents-and-grandparents
#11
Lee Weidauer, Tianna Beare, Teresa Binkley, Maggie Minett, Bonny Specker
BACKGROUND: Osteoarthritis (OA) is one of the leading causes of disability in the world. Several genes are associated with the development of OA, and previous studies have shown adult children of individuals with OA have higher areal bone mineral density (BMD). Because childhood is an important period of growth and bone development, and body composition is known to be associated with BMD, we speculated that there may be differences in growth and bone measures among young children with a genetic predisposition to OA...
May 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29427092/treatment-of-tibial-nonunion-with-bone-defect-using-a-heterotopic-ossification-as-autologous-bone-graft-literature-overview-and-case-report
#12
REVIEW
Michael Schlumberger, Raul Mayr, Christian Koidl, Martin Eichinger, Tobias Roth
INTRODUCTION: Nonunion after open fracture of the lower leg is a frequent complication with a prevalence of up to 40%. In cases with major bone defects, revision of the osteosynthesis with bone grafting is commonly performed. Until today, there is no report on treatment of a tibial nonunion with transplantation of a heterotopic ossification. PRESENTATION OF CASE: We present a case of a 27-year-old male patient, who suffered from a paragliding accident with major injuries...
May 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29415458/alterations-of-subchondral-bone-progenitor-cells-in-human-knee-and-hip-osteoarthritis-lead-to-a-bone-sclerosis-phenotype
#13
Daniel Bianco, Atanas Todorov, Tomislav Čengić, Geert Pagenstert, Stefan Schären, Cordula Netzer, Thomas Hügle, Jeroen Geurts
Subchondral bone tissue plays a key role in the initiation and progression of human and experimental osteoarthritis and has received considerable interest as a treatment target. Elevated bone turnover and remodeling leads to subchondral bone sclerosis that is characterized by an increase in bone material that is less mineralized. The aim of this study was to investigate whether perturbations in subchondral bone-resident progenitor cells might play a role in aberrant bone formation in osteoarthritis. Colony formation assays indicated similar clonogenicity of progenitor cells from non-sclerotic and sclerotic subchondral trabecular bone tissues of osteoarthritic knee and hip joints compared with controls from iliac crest bone...
February 6, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29351755/bone-mineral-density-at-the-hip-and-its-relation-to-fat-mass-and-lean-mass-in-adolescents-the-troms%C3%A3-study-fit-futures
#14
Anne Winther, Lone Jørgensen, Luai Awad Ahmed, Tore Christoffersen, Anne-Sofie Furberg, Guri Grimnes, Rolf Jorde, Ole Andreas Nilsen, Elaine Dennison, Nina Emaus
BACKGROUND: Positive association between body weight and bone mass is well established, and the concept of body mass index (BMI) is associated with higher areal bone mineral density (aBMD) and reduced fracture risk. BMI, that comprises both fat mass (FM) and lean mass (LM) may contribute to peak bone mass achievement in different ways. This study explored the influence of body composition in terms of total body LM and FM on hip aBMD-values in adolescence. METHODS: In 2010/2011, 93% of the region's first-year upper-secondary school students (15-17 years old) in Tromsø, Norway attended the Tromsø Study, Fit Futures...
January 19, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29283748/femoral-neck-stress-in-older-adults-during-stair-ascent-and-descent
#15
Chen Deng, Jason C Gillette, Timothy R Derrick
A detailed understanding of the hip loading environment is needed to help prevent hip fractures, minimize hip pain, rehabilitate hip injuries and design osteogenic exercises for the hip. The purpose of this study was to compare femoral neck stress during stair ascent and descent and to identify the contribution of muscles and reaction forces to the stress environment in mature adult subjects (n=17; age: 50-65 years). Motion analysis and inverse dynamics were combined with musculoskeletal modelling and optimization, then used as input to an elliptical femoral neck cross-section model to estimate femoral neck stress...
December 28, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/29282554/soccer-helps-build-strong-bones-during-growth-a-systematic-review-and-meta-analysis
#16
REVIEW
Gabriel Lozano-Berges, Ángel Matute-Llorente, Alejandro González-Agüero, Alejandro Gómez-Bruton, Alba Gómez-Cabello, Germán Vicente-Rodríguez, José A Casajús
The aim of this study was to analyze the effects of soccer practice on bone in male and female children and adolescents. MEDLINE, PubMed, SPORTDiscus and Web of Science databases were searched for scientific articles published up to and including October 2016. Twenty-seven studies were included in this systematic review (13 in the meta-analysis). The meta-analysis was performed by using OpenMeta[Analyst] software. It is well documented that soccer practice during childhood provides positive effects on bone mineral content (BMC) and density (BMD) compared to sedentary behaviors and other sports, such as tennis, weightlifting, or swimming...
March 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29250336/preoperative-planning-for-redirective-periacetabular-osteotomies
#17
REVIEW
Christoph E Albers, Piet Rogers, Nicholas Wambeek, Sufian S Ahmad, Piers J Yates, Gareth H Prosser
Redirective, periacetabular osteotomies (PAO) represent a group of surgical procedures for treatment of developmental dysplasia of the hip (DDH) in skeletally mature and immature patients. The ultimate goal of all procedures is to reduce symptoms, improve function and delay or prevent progression of osteoarthritis. During the last two decades, the understanding of the underlying pathomechanisms has continuously evolved. This is mainly attributable to the development of the femoroacetabular impingement concept that has increased the awareness of the underlying three-dimensional complexity associated with DDH...
December 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/29225159/histopathology-of-periarticular-non-hereditary-heterotopic-ossification
#18
Kristin L Foley, Nader Hebela, Mary Ann Keenan, Robert J Pignolo
In the mature adult skeleton, new bone formation is normally restricted to regeneration of osseous tissue at sites of fracture. However, heterotopic ossification, or the formation of bone outside the normal skeleton, can occur within muscle, adipose, or fibrous connective tissue. Periarticular non-hereditary heterotopic ossification (NHHO) may occur after musculoskeletal trauma, following CNS injury, with certain arthropathies, or following injury or surgery that is often sustained in the context of age-related pathology...
December 7, 2017: Bone
https://www.readbyqxmd.com/read/29201291/long-term-results-of-modified-salter-innominate-osteotomy-for-legg-calv%C3%A3-perthes-disease
#19
Kyung Soon Park, Kyu Jin Cho, Hong Yeol Yang, Kamolhuja Eshnazarovich Eshnazarov, Taek Rim Yoon
Background: In a previous study, we reported clinical and radiographic results of our modified Salter innominate osteotomy technique in 16 hips affected by Legg-Calvé-Perthes disease (LCPD) with an average follow-up of 31.8 months. In this study, we present the long-term results of the osteotomy in LCPD patients followed until physeal closure. Methods: Thirty hips of 29 patients were followed until skeletal maturation after modified Salter innominate osteotomy...
December 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/29181348/focal-periphyseal-edema-zone-on-magnetic-resonance-imaging-in-the-greater-trochanter-apophysis-a-case-report
#20
Akio Sakamoto, Shuichi Matsuda
Introduction: Magnetic resonance imaging (MRI) has been used to identify focal bone marrow edema or a focal periphyseal edema (FOPE) zone, in the closing growth plates of adolescent knees. Case Report: In the current case, an 11-year-old boy reported pain in his left hip. He had been participating in gymnastic classes at school, but otherwise, he was not an active athlete. Based on MRI findings, he was diagnosed with a FOPE zone in his greater trochanteric apophysis...
July 2017: Journal of Orthopaedic Case Reports
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