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Hip development

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https://www.readbyqxmd.com/read/29451944/total-hip-arthroplasty-in-patients-with-avascular-necrosis-after-hematopoietic-stem-cell-transplantation
#1
Anita Vijapura, Harlan B Levine, Michele Donato, Mark A Hartzband, Melissa Baker, Gregg R Klein
The immunosuppressive regimens required for hematopoietic stem cell transplantation predispose recipients to complications, including avascular necrosis. Cancer-related comorbidities, immunosuppression, and poor bone quality theoretically increase the risk for perioperative medical complications, infection, and implant-related complications in total joint arthroplasty. This study reviewed 20 primary total hip arthroplasties for avascular necrosis in 14 patients. Outcomes were assessed at routine clinical visits and Harris hip scores were calculated...
February 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29451057/comparison-between-modified-dunn-procedure-and-in-situ-fixation-for-severe-stable-slipped-capital-femoral-epiphysis
#2
Giovanni Trisolino, Stefano Stilli, Giovanni Gallone, Pedro Santos Leite, Giovanni Pignatti
Background and purpose - The best treatment option for severe slipped capital femoral epiphysis (SCFE) is still controversial. We compared clinical and radiographic outcomes of modified Dunn procedure (D) and in situ fixation (S) in severe SCFE. Patients and methods - We retrospectively compared D and S, used for severe stable SCFE (posterior sloping angle (PSA) > 50°) in 29 patients (15 D; 14 S). Propensity analysis and inverse probability of treatment weights (IPTW) to adjust for baseline differences were performed...
February 16, 2018: Acta Orthopaedica
https://www.readbyqxmd.com/read/29449003/upper-partial-fibulectomy-improves-knee-biomechanics-and-function-and-decreases-knee-pain-of-osteoarthritis-a-pilot-and-biomechanical-study
#3
Yong Nie, Jun Ma, ZeYu Huang, Bin Xu, Shuo Tang, Bin Shen, Virginia Byers Kraus, FuXing Pei
To investigate the change in clinical outcomes and biomechanical properties of the knee in response to upper partial fibulectomy. Sixteen patients with medial compartment knee osteoarthritis (KOA) underwent upper partial fibulectomy. Visual analog scale (VAS) pain, the hospital for special surgery knee score (HSS), hip-knee-ankle (HKA) angle (measured in the frontal plane), and flexion/extension range of motion of the knee were assessed before and up to 6 months after surgery. Patients were evaluated for gait parameters and overall peak knee adduction moment (KAM)...
December 13, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29448132/%C3%AE-calpain-capn1-calpastatin-cast-and-growth-hormone-receptor-ghr-genetic-effects-on-angus-beef-heifer-performance-traits-and-reproduction
#4
Richard G Tait, Robert A Cushman, Anthony K McNeel, Eduardo Casas, Timothy P L Smith, Harvey C Freetly, Gary L Bennett
Genetic marker effects and type of inheritance are estimated with poor precision when minor marker allele frequencies are low. An Angus population was subjected to marker assisted selection for multiple years to equalize CAPN1 haplotypes, CAST, and GHR genetic marker frequencies. The objective was to estimate the pleiotropic effects of these carcass quality oriented markers for body weight, reproduction, and first calf performance traits in 174 replacement beef females which were managed under 2 post-weaning development protocols...
February 3, 2018: Theriogenology
https://www.readbyqxmd.com/read/29446787/the-treatment-of-femoral-fractures-in-children-with-cerebral-palsy
#5
P Persiani, M Murgia, F M Ranaldi, O Mazza, M Mariani, M Crostelli, C Villani
OBJECTIVE: The purpose of this study is to retrospectively evaluate a group of children affected by cerebral palsy with a recent femoral fracture, and to analyse the results and complications in relation to the treatment used. MATERIALS AND METHODS: The analysis was performed on 36 children (21 M, 15 F, 8-14 years old) with cerebral palsy (7 diplegia, 28 tetraparesis, 1 hemiplegia) with a metaphyseal or a diaphyseal femoral fracture. The patients were subdivided into two groups according to their Gross Motor Function Classification System (GMFCS) level: level 2-3 (9 patients) and level 4-5 (27 patients), evaluating the presence of complications and malunions for each group at the end of each follow up...
January 2018: La Clinica Terapeutica
https://www.readbyqxmd.com/read/29443839/how-common-and-how-serious-is-clostridium-difficile-colitis-after-geriatric-hip-fracture-findings-from-the-nsqip-dataset
#6
Patawut Bovonratwet, Daniel D Bohl, Glenn S Russo, Nathaniel T Ondeck, Denis Nam, Craig J Della Valle, Jonathan N Grauer
BACKGROUND: Patients with geriatric hip fractures may be at increased risk for postoperative Clostridium difficile colitis, which can cause severe morbidity and can influence hospital quality metrics. However, to our knowledge, no large database study has calculated the incidence of, factors associated with, and effect of C. difficile colitis on geriatric patients undergoing hip fracture surgery. QUESTIONS/PURPOSES: To use a large national database with in-hospital and postdischarge data (National Surgical Quality Improvement Program [NSQIP®]) to (1) determine the incidence and timing of C...
March 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29443824/improving-hip-worn-accelerometer-estimates-of-sitting-using-machine-learning-methods
#7
Jacqueline Kerr, Jordan Carlson, Suneeta Godbole, Lisa Cadmus-Bertram, John Bellettiere, Sheri Hartman
PURPOSE: To improve estimates of sitting time from hip worn accelerometers used in large cohort studies by employing machine learning methods developed on free living activPAL data. METHODS: Thirty breast cancer survivors concurrently wore a hip worn accelerometer and a thigh worn activPAL for 7 days. A random forest classifier, trained on the activPAL data, was employed to detect sitting, standing and sit-stand transitions in 5 second windows in the hip worn accelerometer...
February 13, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29441427/isolated-focal-cartilage-and-labral-defects-in-patients-with-femoroacetabular-impingement-syndrome-may-represent-new-unique-injury-patterns
#8
Ashley L Kapron, Stephen K Aoki, Jeffrey A Weiss, Aaron J Krych, Travis G Maak
PURPOSE: Develop a framework to quantify the size, location and severity of femoral and acetabular-sided cartilage and labral damage observed in patients undergoing hip arthroscopy, and generate a database of individual defect parameters to facilitate future research and treatment efforts. METHODS: The size, location, and severity of cartilage and labral damage were prospectively collected using a custom, standardized post-operative template for 100 consecutive patients with femoroacetabular impingement syndrome...
February 13, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29439949/lower-limb-biomechanics-in-femoroacetabular-impingement-syndrome-a-systematic-review-and-meta-analysis
#9
REVIEW
Matthew G King, Peter R Lawrenson, Adam I Semciw, Kane J Middleton, Kay M Crossley
OBJECTIVE: (1) Identify differences in hip and pelvic biomechanics in patients with femoroacetabular impingement syndrome (FAIS) compared with controls during everyday activities (eg, walking, squatting); and (2) evaluate the effects of interventions on hip and pelvic biomechanics during everyday activities. DESIGN: Systematic review. DATA SOURCES: Medline, CINAHL, EMBASE, Scopus and SPORTDiscus until February 2017. METHODS: Primary aim: studies that investigated hip or pelvic kinematics and/or joint torques of everyday activities in patients with FAIS compared with the asymptomatic contralateral limb or a control group...
February 13, 2018: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/29439274/relation-of-paraoxonase-1-activity-with-biochemical-variables-brachial-artery-intima-media-thickness-in-patients-with-diabetes-with-or-without-obesity
#10
Pinar Karakaya, Bahar Ozdemir, Meral Mert, Yildiz Okuturlar
AIM: The sodium-sparing effect of insulin leads to increase in total sodium pool of the body which is a chronic stimulus for atrial natriuretic peptide (ANP). In our study we aimed to determine the relationship between ANP and microvascular complications of diabetes. METHODS: 60 patients, 30-70 years old, with the diagnosis of type 2 diabetes mellitus (DM) are enrolled into the study. Patients with a chronic disease other than DM are excluded. Blood samples for routine biochemical tests are taken after at least 12 h fasting at 8-9 am...
February 14, 2018: Obesity Facts
https://www.readbyqxmd.com/read/29437055/aseptic-revision-total-hip-arthroplasty-in-the-elderly-quantifying-the-risks-for-patients-over-80-years-old
#11
P Bovonratwet, R Malpani, T D Ottesen, V Tyagi, N T Ondeck, L E Rubin, J N Grauer
AIMS: The aim of this study was to compare the rate of perioperative complications following aseptic revision total hip arthroplasty (THA) in patients aged ≥ 80 years with that in those aged < 80 years, and to identify risk factors for the incidence of serious adverse events in those aged ≥ 80 years using a large validated national database. PATIENTS AND METHODS: Patients who underwent aseptic revision THA were identified in the 2005 to 2015 National Surgical Quality Improvement Program (NSQIP) database and stratified into two age groups: those aged < 80 years and those aged ≥ 80 years...
February 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29435594/-periacetabular-osteotomy-what-influence-does-age-have-on-patient-relevant-results-a-prospective-5%C3%A2-year-investigation
#12
L Franken, F Thielemann, A Postler, S Blum, A Hartmann, K-P Günther, J Goronzy
INTRODUCTION: Periacetabular osteotomy (PAO) is an effective procedure in treatment of symptomatic hip dysplasia. To achieve a good outcome a strict patient selection has to be applied. The aim of this study was to evaluate the influence of patient age at surgery on clinical outcome. METHODS: In a prospective study 86 patients (106 hips) underwent clinical and radiographic follow-up at a mean time of 5 years (2.5-8.5 years) after PAO. Patient-related outcome measurements (PROMs: EQ-5D, WOMAC, OHS, GTO) were applied preoperatively as well as postoperatively and the deformity correction as well as development of osteoarthritis were evaluated...
February 12, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29434922/association-of-abnormal-glucose-metabolism-and-insulin-resistance-in-patients-with-atypical-and-typical-endometrial-cancer
#13
Yongjing Lai, Chuanying Sun
This study aimed to detect glucose metabolism indicators and insulin resistance index in patients with endometrial cancer, and to explore the clinical significance and correlation between them. A total of 65 patients with endometrial cancer (52 of typical endometrial and 13 cases of atypical endometrial cancer patients, 27 with diabetes mellitus, and 38 cases without diabetes mellitus) were selected at the People's Hospital of Rizhao from June, 2010 to June, 2016 to serve as the observation group. During the same period, 62 patients with endometrial benign lesions (24 with diabetes mellitus and 38 cases without diabetes mellitus) were selected as the control group...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29432506/eating-habits-and-nutritional-status-of-patients-with-affective-disorders-and-schizophrenia
#14
Ewa Stefańska, Magdalena Lech, Agnieszka Wendołowicz, Beata Konarzewska, Napoleon Waszkiewicz, Lucyna Ostrowska
OBJECTIVES: The aim of the study was to assess the nutritional value of the food intake in the group of men and women suffering from recurrent affective disorders and schizophrenia, and also to determine the relation between selected nutritional parameters with anthropometric indices defining the nutritional status of the subjects. METHODS: 219 persons participated in the study (61 patients with recurrent depressive disorders, 60 patients with schizophrenia and 98 healthy volunteers)...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29432264/longitudinal-growth-and-pqct-measures-in-hutterite-children-and-grandchildren-are-associated-with-prevalence-of-hip-or-knee-replacement-resulting-from-osteoarthritis-in-parents-and-grandparents
#15
Lee Weidauer, Tianna Beare, Teresa Binkley, Maggie Minett, Bonny Specker
BACKGROUND: Osteoarthritis (OA) is one of the leading causes of disability in the world. Several genes are associated with the development of OA, and previous studies have shown adult children of individuals with OA have higher areal bone mineral density (BMD). Because childhood is an important period of growth and bone development, and body composition is known to be associated with BMD, we speculated that there may be differences in growth and bone measures among young children with a genetic predisposition to OA...
February 8, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29430633/phacomatosis-pigmentokeratotica-a-case-of-hras-mosaicism-causing-rhabdomyosarcoma
#16
M Prieto-Barrios, R Llamas-Martin, V Velasco-Tamariz, A Calleja-Algarra, Y Ruano, P L Ortiz-Romero, J L Rodriguez-Peralto
A 17-year-old male presented with a large sebaceous naevus (SN) comprising part of his left face and scalp and a speckled lentiginous naevus (SLN) on his right trunk, hip, neck and scalp with a checkerboard pattern. His right oral hemimucosa showed extensive papillomatous lesions which were contiguous to the upper lip SN lesions. As for extracutaneous manifestations he suffered from cardiac, musculoskeletal and ocular alterations. On the other hand, he developed two primary rhabdomyosarcomas. DNA samples of the SN, SLN, the oral papillomatous hyperplasia and both rhabdomyosarcomas were analyzed by Sanger sequencing...
February 12, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29430049/developing-clinical-procedures-to-diagnose-specific-motor-control-impairments-associated-with-low-back-pain-prone-hip-extension-phe-active-straight-leg-raise-aslr-and-gait-variability
#17
https://www.readbyqxmd.com/read/29429942/pooled-human-serum-a-new-culture-supplement-for-bioreactor-based-cell-therapies-preliminary-results
#18
Sara Savelli, Luisa Trombi, Delfo D'Alessandro, Stefania Moscato, Simone Pacini, Simone Lapi, Fabrizio Scatena, Stefano Giannotti, Mario Petrini
BACKGROUND AIMS: Bone marrow mesenchymal stromal cells (MSCs) are an appealing source for several cell-based therapies. Many bioreactors, such as the Quantum Cell Expansion System, have been developed to generate a large number of MSCs under Good Manufacturing Practice conditions by using human platelet lysate (HPL). Previously, we isolated a novel cell population in human bone marrow, mesodermal progenitor cells (MPCs), which we identified as precursors of MSCs. MPCs may represent an important cell source for regenerative medicine applications...
February 8, 2018: Cytotherapy
https://www.readbyqxmd.com/read/29429067/hip-malformation-is-a-very-common-finding-in-young-patients-scheduled-for-total-hip-arthroplasty
#19
Dennis Karimi, Thomas Kallemose, Anders Troelsen, Jakob Klit
INTRODUCTION: In Denmark, 20% of all registered total hip arthroplasties (THA) from 1995 to 2014 has been patients younger than 60 years with primary idiopathic osteoarthritis (OA). It is speculated that hip malformations may be a major contributor to early OA development. It has been shown that hip malformation may compromise implant position and, therefore, identifying and knowing the incidence of malformations is important. Our aim was to assess the prevalence and type of hip malformations in a cohort of younger patients undergoing THA...
February 10, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29427011/self-learning-computers-for-surgical-planning-and-prediction-of-postoperative-alignment
#20
Renaud Lafage, Sébastien Pesenti, Virginie Lafage, Frank J Schwab
PURPOSE: In past decades, the role of sagittal alignment has been widely demonstrated in the setting of spinal conditions. As several parameters can be affected, identifying the driver of the deformity is the cornerstone of a successful treatment approach. Despite the importance of restoring sagittal alignment for optimizing outcome, this task remains challenging. Self-learning computers and optimized algorithms are of great interest in spine surgery as in that they facilitate better planning and prediction of postoperative alignment...
February 9, 2018: European Spine Journal
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