Elizabeth R Harding, Cara H Kanner, Amy Pasternak, Allan M Glanzman, Sally Dunaway Young, Ashwini K Rao, Michael P McDermott, Zarazuela Zolkipli-Cunningham, John W Day, Richard S Finkel, Basil T Darras, Darryl C De Vivo, Jacqueline Montes
Background: The natural history of spinal muscular atrophy (SMA) is well understood, with progressive muscle weakness resulting in declines in function. The development of contractures is common and negatively impacts function. Clinically, joint hypermobility (JH) is observed but is poorly described, and its relationship with function is unknown. Methods : Lower-limb ROM (range of motion) assessments of extension and flexion at the hip, knee, and ankle were performed. ROMs exceeding the published norms were included in the analysis...
April 30, 2024: Journal of Clinical Medicine