keyword
https://read.qxmd.com/read/38507460/effects-of-osteopathic-manipulative-treatment-on-maternal-fetal-hemodynamics-in-third-trimester-pregnant-women-a-prospective-study
#21
JOURNAL ARTICLE
Maria Luisa Arruda Correia, Fernando Maia Peixoto Filho, Saint Clair Gomes Júnior, Guilherme Ramires de Jesus
OBJECTIVE: To evaluate the maternal-fetal hemodynamic effects after osteopathic manipulative treatment by measuring vital signs and Doppler velocimetry in third-trimester pregnant women. MATERIALS AND METHODS: This is a prospective study with pregnant women undergoing outpatient follow-up and hospitalized in a ward at Instituto Fernandes Figueira/Fiocruz, between August 2021 to August 2022, during the SARS-CoV-2 pandemic. This study was registered in REBEC under Register Number RBR-9q7kvg and approved by the ethics committee under number 32216620...
2024: PloS One
https://read.qxmd.com/read/38505758/effect-of-maternal-serum-albumin-level-on-birthweight-and-gestational-age-an-analysis-of-39200-singleton-newborns
#22
JOURNAL ARTICLE
Jiayi Wu, Xiaorui Liu, Chuanmei Qin, Jinwen Zhang, Xueqing Liu, Jianing Hu, Fan Wu, Cailian Chen, Yi Lin
BACKGROUND: Serum albumin plays a pivotal role in regulating plasma oncotic pressure and modulating fluid distribution among various body compartments. Previous research examining the association between maternal serum albumin levels and fetal growth yielded limited and inconclusive findings. Therefore, the specific influence of serum albumin on fetal growth remains poorly understood and warrants further investigation. METHODS: A retrospective study involved 39200 women who had a singleton live birth at a tertiary-care academic medical center during the period from January 2017 to December 2020...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38505478/charge-syndrome-with-early-fetal-ear-abnormalities-a-case-report
#23
Yu Liang, Sijie He, Liuqiao Yang, Tao Li, Lijian Zhao, Cong-Xin Sun
KEY CLINICAL MESSAGE: CHARGE syndrome is a rare genetic disorder characterized by several distinct features. The presence of fetal ear abnormalities could be the early indicator of CHARGE syndrome. Subsequent prenatal diagnosis is essential to confirm the disorder. This is significant because the patient may receive genetic counseling and appropriate disposal based on the accurate diagnosis. ABSTRACT: CHARGE syndrome is a rare genetic disorder with multiple specific clinical features...
March 2024: Clinical Case Reports
https://read.qxmd.com/read/38505161/our-experience-with-management-of-congenital-urological-pathologies-in-adulthood-what-pediatric-urologists-should-know-and-adult-urologists-adopt-in-pediatric-practice-experience
#24
JOURNAL ARTICLE
Leon Chertin, Binyamin B Neeman, Jawdat Jaber, Guy Verhovsky, Amnon Zisman, Ariel Mamber, Ilan Kafka, Ala Eddin Natsheh, Dmitry Koulikov, Ofer Z Shenfeld, Boris Chertin, Stanislav Koucherov, Amos Neheman
PURPOSE: To summarize our experience in the management of congenital anomalies in the kidney and urinary tract (CAKUT) in adults. MATERIALS AND METHODS: We conducted a retrospective chart review of all adult patients who underwent primary surgical intervention for CAKUT between 1998 and 2021. RESULTS: The study included 102 patients with a median age of 25 (interquartile range, 23-36.5). Of these, 85 (83.3%) patients reported normal prenatal ultrasound, and the remaining 17 (16...
March 2024: Current Urology
https://read.qxmd.com/read/38504427/prenatal-diagnosis-of-ror-2-related-robinow-syndrome-presenting-with-fetal-ultrasound-findings-of-mesomelia-vertebral-digital-and-genital-abnormalities
#25
Liying Yang, Patrick Shannon, Rachel Silver, Maian Roifman, Carin Yates, David Chitayat
Autosomal recessive ROR2-Robinow syndrome is caused by pathogenic variants in the ROR2 gene. Fetal ultrasound done on our patient at 24 + 3/7 weeks gestation showed macrocephaly, brachycephaly, flat face, prominent forehead, mild frontal bossing, lower thoracic hemivertebrae, digital abnormalities and micropenis. Fetal trio whole exome sequencing done on amniocytes showed two pathogenic compound heterozygous variants in the ROR2 gene, c.1324 C > T; p.(Arg442*) maternally inherited and c.1366dup; p...
March 19, 2024: Prenatal Diagnosis
https://read.qxmd.com/read/38503486/morphologic-development-of-the-first-trimester-utero-placental-vasculature-is-positively-associated-with-embryonic-and-fetal-growth-the-rotterdam-periconception-cohort
#26
JOURNAL ARTICLE
E S De Vos, A G M G J Mulders, A H J Koning, S P Willemsen, M Rousian, B B Van Rijn, E A P Steegers, R P M Steegers-Theunissen
STUDY QUESTION: Is morphologic development of the first-trimester utero-placental vasculature associated with embryonic growth and development, fetal growth, and birth weight percentiles? SUMMARY ANSWER: Using the utero-placental vascular skeleton (uPVS) as a new imaging marker, this study reveals morphologic development of the first-trimester utero-placental vasculature is positively associated with embryonic growth and development, fetal growth, and birth weight percentiles...
March 19, 2024: Human Reproduction
https://read.qxmd.com/read/38500935/incidental-prenatal-diagnosis-of-congenital-inguinal-hernia-a-case-report
#27
Samir Asfour, Abdelsalam Alkharouf, Yara Sultan, Laila Qarawi, Amal Shraim, Muhannad Wael
Prenatal congenital inguinal hernia is a rare condition, with limited cases reported in the literature. Accurate prenatal diagnosis is crucial for appropriate management and outcomes. We report a case of a 44-year-old woman at 36 weeks of gestation with well-controlled gestational diabetes diagnosed with prenatal congenital inguinal hernia. The patient's antenatal history included abnormal first-trimester screening tests for Down syndrome, but subsequent amniocentesis revealed no chromosomal abnormalities...
February 2024: Curēus
https://read.qxmd.com/read/38500903/comparing-transvaginal-ultrasound-measurements-of-cervical-length-to-bishop-score-in-predicting-cesarean-section-following-induction-of-labor-a-prospective-observational-study
#28
JOURNAL ARTICLE
Parul Sinha, Mansi Gupta, Snehlata Meena
INTRODUCTION:  Bishop score (BS) has been used to see the favorability of the cervix for induction of labor (IOL), but it has limitations in today's diverse patient population. We aimed to assess the predictive value of transvaginal ultrasound (TVUS) measurements of cervical length (CL) compared to BS in determining the likelihood of cesarean section (CS) following IOL. METHODOLOGY: A prospective observational study was conducted on 120 women requiring IOL in a tertiary care hospital in central India...
February 2024: Curēus
https://read.qxmd.com/read/38500900/medical-imaging-in-pregnancy-safety-appropriate-utilization-and-alternative-modalities-for-imaging-pregnant-patients
#29
REVIEW
Abdullah A Albakri, Mohammed M Alzahrani, Saeed H Alghamdi
This article reviews the existing literature on diagnostic and medical imaging of pregnant women, the risks and safety measures of different medical imaging modalities, and alternative modalities for imaging pregnant patients. Different medical imaging modalities such as MRI, CT scan, ultrasound, nuclear medicine, and X-ray imaging help to evaluate women with recognized or unrecognized pregnancies and identify any underlying complications among pregnant patients. Fetuses are more sensitive to radiation and the effects of medical imaging as compared to adults since they have a rapidly developing cell system...
February 2024: Curēus
https://read.qxmd.com/read/38498837/first-trimester-maternal-tryptophan-metabolism-and-embryonic-and-fetal-growth-the-rotterdam-periconceptional-cohort-predict-study
#30
JOURNAL ARTICLE
Sofie K M van Zundert, Nina C M van Egmond, Lenie van Rossem, Sten P Willemsen, Pieter H Griffioen, Ron H N van Schaik, Mina Mirzaian, Régine P M Steegers-Theunissen
STUDY QUESTION: What is the association between first trimester maternal tryptophan (TRP) metabolites and embryonic and fetal growth? SUMMARY ANSWER: Higher 5-hydroxytryptophan (5-HTP) concentrations are associated with reduced embryonic growth and fetal growth and with an increased risk of small-for-gestational age (SGA), while higher kynurenine (KYN) concentrations are associated with a reduced risk of SGA. WHAT IS KNOWN ALREADY: The maternal TRP metabolism is involved in many critical processes for embryonic and fetal growth, including immune modulation and regulation of vascular tone...
March 18, 2024: Human Reproduction
https://read.qxmd.com/read/38498267/doppler-ultrasound-of-umbilical-and-middle-cerebral-artery-in-third-trimester-small-for-gestational-age-fetuses-to-decide-on-timing-of-delivery-for-suspected-fetal-growth-restriction-a-cohort-with-nested-rct-drigitat
#31
JOURNAL ARTICLE
Mauritia C Marijnen, Hester D Kamphof, Stefanie E Damhuis, Maddy Smies, Aleid G Leemhuis, Hans Wolf, Sanne J Gordijn, Wessel Ganzevoort
OBJECTIVE: To assess the association of the umbilicocerebral ratio (UCR) with adverse perinatal outcome in late preterm small-for-gestational age (SGA) fetuses and to investigate the effect on perinatal outcomes of immediate delivery. DESIGN: Multicentre cohort study with nested randomised controlled trial (RCT). SETTING: Nineteen secondary and tertiary care centres. POPULATION: Singleton SGA pregnancies (estimated fetal weight [EFW] or fetal abdominal circumference [FAC] <10th centile) from 32 to 36+6  weeks...
February 5, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
https://read.qxmd.com/read/38498110/prenatal-phenotype-of-a-homozygous-nonsense-mpdz-variant-in-a-fetus-with-severe-congenital-hydrocephalus
#32
JOURNAL ARTICLE
Nathalie Vanden Eynde, Eve Van den Mooter, Elise Vantroys, Elke De Schutter, Astrid Leus, Kathelijn Keymolen, Boyan Dimitrov, Kim van Berkel
The fetal phenotype of MPDZ-associated congenital hydrocephalus type 2 with or without brain or eye anomalies (HYC2) (OMIM 615219) is not well described in the literature. The present case shows not previously published clinical fetal features that are detected during routine second trimester ultrasound screening at 21 weeks of gestation such as bilateral ventriculomegaly, lean cavum septum pellucidum, suspicion of hypoplastic corpus callosum, and suspicion of gyration disorder with normal fossa posterior...
March 18, 2024: Prenatal Diagnosis
https://read.qxmd.com/read/38497811/enlarged-cavum-septum-pellucidum-and-small-thymus-as-markers-for-22q11-2-deletion-syndrome
#33
JOURNAL ARTICLE
Kimberly B Gaiser, Erica M Schindewolf, Laura J Conway, Beverly G Coleman, Edward R Oliver, Jack R Rychik, Suzanne E Debari, Donna M Mcdonald-Mcginn, Elaine H Zackai, Julie S Moldenhauer, Juliana S Gebb
BACKGROUND: Enlarged cavum septum pellucidum (CSP) and hypoplastic thymus are proposed extra-cardiac fetal markers for 22q11.2 deletion syndrome. We sought to determine if they were part of the fetal phenotype of our cohort of fetuses with 22q11.2 deletion syndrome. METHODS: Case-control study of fetuses evaluated from 2016 to 2022. The study group included fetuses with laboratory confirmation of 22q11.2 deletion syndrome. The control group included pregnancies with conotruncal cardiac anomalies with normal microarray as well as structurally normal fetuses with normal microarray...
March 18, 2024: Prenatal Diagnosis
https://read.qxmd.com/read/38497455/human-observer-sensitivity-to-temporal-noise-during-b-mode-ultrasound-scanning-characterization-and-imaging-implications
#34
JOURNAL ARTICLE
Matthew T Huber, Katelyn M Flint, Patricia J McNally, Sarah C Ellestad, Gregg E Trahey
This work measures temporal signal-to-noise ratio (SNR) thresholds that indicate when random noise during ultrasound scanning becomes imperceptible to expert human observers. Visible noise compromises image quality and can potentially lead to non-diagnostic scans. Noise can arise from both stable acoustic sources (clutter) or randomly varying electronic sources (temporal noise). Extensive engineering effort has focused on decreasing noise in both of these categories. In this work, an observer study with five practicing sonographers was performed to assess sonographer sensitivity to temporal noise in ultrasound cine clips...
March 18, 2024: Ultrasonic Imaging
https://read.qxmd.com/read/38496357/cfdna-from-maternal-plasma-for-noninvasive-screening-of-fetal-exomes
#35
JOURNAL ARTICLE
Longwei Qiao
In recent years, a shift in prenatal screening methods has been observed, moving away from traditional approaches such as ultrasound and maternal serologic markers towards the utilization of noninvasive prenatal testing (NIPT) based on cfDNA extracted from peripheral blood. This cutting-edge technology has established itself as the primary screening method, attributed to its superior detection rate and reduced false-positive rate. Although NIPT predominantly focuses on screening for chromosomal abnormalities, it currently does not encompass the identification of single-gene disorders...
2024: American Journal of Clinical and Experimental Immunology
https://read.qxmd.com/read/38496096/the-influence-of-abstinence-interval-on-semen-quality-and-its-effect-on-an-assisted-reproductive-technology-art-pregnancy-a-case-report
#36
Rokaiya Shaikh, Akash More, Shilpa Dutta, Namrata Choudhary, Shivani Khemani
This case report focuses on a couple facing primary infertility, where the male partner exhibited asthenoteratozoospermia and high DNA fragmentation. The treatment approach involved three cycles of intracytoplasmic sperm injection (ICSI), an assisted reproductive technology (ART), to indicate and address the specific challenges posed by male factor infertility. The initial two attempts failed as DNA fragmentation was high, which was observed on days 4 and 3 of abstinence, respectively. In the third cycle, DNA fragmentation was low on day 2 of the abstinence period, resulting in the successful formation and cryopreservation of embryos...
February 2024: Curēus
https://read.qxmd.com/read/38495518/accuracy-of-prenatal-and-postnatal-biomarkers-for-estimating-gestational-age-a-systematic-review-and-meta-analysis
#37
JOURNAL ARTICLE
Elizabeth Bradburn, Agustin Conde-Agudelo, Nia W Roberts, Jose Villar, Aris T Papageorghiou
BACKGROUND: Knowledge of gestational age (GA) is key in clinical management of individual obstetric patients, and critical to be able to calculate rates of preterm birth and small for GA at a population level. Currently, the gold standard for pregnancy dating is measurement of the fetal crown rump length at 11-14 weeks of gestation. However, this is not possible for women first presenting in later pregnancy, or in settings where routine ultrasound is not available. A reliable, cheap and easy to measure GA-dependent biomarker would provide an important breakthrough in estimating the age of pregnancy...
April 2024: EClinicalMedicine
https://read.qxmd.com/read/38494071/vasa-previa-in-singleton-pregnancies-diagnosis-and-clinical-management-based-on-an-international-expert-consensus
#38
JOURNAL ARTICLE
Yinka Oyelese, Ali Javinani, Brittany Gudanowski, Eyal Krispin, Andrei Rebarber, Ranjit Akolekar, Val Catanzarite, Rohan D'Souza, Richard Bronsteen, Anthony Odibo, Matthias A Scheier, Junichi Hasegawa, Eric Jauniaux, Christoph Lees, Deepa Srinivasan, Elizabeth Daly-Jones, Gregory Duncombe, Yaacov Melcer, Ron Maymon, Robert Silver, Federico Prefumo, Daisuke Tachibana, Wolfgang Henrich, Robert Cincotta, Scott A Shainker, Angela C Ranzini, Ashley S Roman, Ramen Chmait, Edgar A Hernandez-Andrade, Daniel L Rolnik, Waldo Sepulveda, Alireza A Shamshirsaz
BACKGROUND: There are limited data to guide the diagnosis and management of vasa previa. Currently, what is known is largely based on case reports or series and cohort studies. OBJECTIVE: (s): To systematically collect and classify expert opinions and achieve consensus on the diagnosis and clinical management of vasa previa using focus group discussions (FGD) and a Delphi technique. STUDY DESIGN: A four-round FGD and a three-round Delphi survey of an international panel of experts on vasa previa were conducted...
March 15, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38492743/-antenatal-care-for-fetuses-with-congenital-diaphragmatic-hernia
#39
JOURNAL ARTICLE
Charles Mégier, Alexandra Letourneau, Lina Bejjani, Meriem Macha Boumerzoug, Cécile Suffee, Van Huynh, Julien Saada, Grégoire Dumery, Alexandra Benachi
Congenital diaphragmatic hernia (CDH) can be diagnosed prenatally and its severity assessed by fetal imaging. The prognosis of a fetus with CDH is based on whether or not the hernia is isolated, the measurement of lung volume on ultrasound and MRI, and the position of the liver. The birth of a child with CDH should take place in a center adapted to the care of such children, and in accordance with the recommendations defined by the French National Diagnosis and Care Protocol. It has recently been demonstrated that for moderate and severe forms of CDH, tracheal occlusion using a balloon placed in utero by fetoscopy (FETO) increases survival until discharge from the neonatal unit, but at the cost of an increased risk of prematurity...
March 14, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
https://read.qxmd.com/read/38490217/diagnostic-potential-of-complementation-of-mri-to-prenatal-ultrasound-for-detecting-orofacial-clefts-in-high-risk-fetuses-a-network-meta-analysis
#40
JOURNAL ARTICLE
Jing Zhai, Shuyan You, Zhonghua Liang, Haihua Yu, Chengfeng Zhu, Lu Han
OBJECTIVE: To compare the complementation of magnetic resonance imaging (MRI) to prenatal ultrasound (US) with prenatal US alone in detecting orofacial clefts in high-risk fetuses. DESIGN: A network meta-analysis. SETTING: Literature retrieval in PubMed, EMBASE, and Cochrane library, and meta-analysis based on STATA 14.0. PATIENTS: Fetuses were at high-risk for orofacial clefts. INTERVENTIONS: Prenatal US and the complementation of MRI to prenatal US...
March 15, 2024: Cleft Palate-craniofacial Journal
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