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JOURNAL ARTICLE
Jonas Ghouse, Gardar Sveinbjörnsson, Marijana Vujkovic, Anne-Sofie Seidelin, Helene Gellert-Kristensen, Gustav Ahlberg, Vinicius Tragante, Søren A Rand, Joseph Brancale, Silvia Vilarinho, Pia Rengtved Lundegaard, Erik Sørensen, Christian Erikstrup, Mie Topholm Bruun, Bitten Aagaard Jensen, Søren Brunak, Karina Banasik, Henrik Ullum, Niek Verweij, Luca Lotta, Aris Baras, Tooraj Mirshahi, David J Carey, David E Kaplan, Julie Lynch, Timothy Morgan, Tae-Hwi Schwantes-An, Daniel R Dochtermann, Saiju Pyarajan, Philip S Tsao, Triin Laisk, Reedik Mägi, Julia Kozlitina, Anne Tybjærg-Hansen, David Jones, Kirk U Knowlton, Lincoln Nadauld, Egil Ferkingstad, Einar S Björnsson, Magnus O Ulfarsson, Árni Sturluson, Patrick Sulem, Ole B Pedersen, Sisse R Ostrowski, Daniel F Gudbjartsson, Kari Stefansson, Morten Salling Olesen, Kyong-Mi Chang, Hilma Holm, Henning Bundgaard, Stefan Stender
We report a multi-ancestry genome-wide association study on liver cirrhosis and its associated endophenotypes, alanine aminotransferase (ALT) and γ-glutamyl transferase. Using data from 12 cohorts, including 18,265 cases with cirrhosis, 1,782,047 controls, up to 1 million individuals with liver function tests and a validation cohort of 21,689 cases and 617,729 controls, we identify and validate 14 risk associations for cirrhosis. Many variants are located near genes involved in hepatic lipid metabolism...
April 17, 2024: Nature Genetics
#2
JOURNAL ARTICLE
Abraham Dejene, Zoie Carter, Erin Woo, Shufang Sun, Eric B Loucks, Jeffrey Proulx
BACKGROUND: There is a lack of mindfulness instructors from underserved/underrepresented communities who have completed systematic mindfulness teacher-training programs to meet the growing demand for culturally responsive mindfulness training in those communities. OBJECTIVES: To investigate strategies for increasing the representation of Mindfulness-Based Stress Reduction (MBSR) teachers who serve historically underrepresented racial and ethnic groups. METHODS: Conducted through 4 one-hour Zoom focus groups (n = 54; women = 74%), this study queried individuals with experience serving underrepresented racial and ethnic communities, and had mindfulness experience, on how to increase participation from underrepresented communities in mindfulness...
2024: Glob Adv Integr Med Health
#3
JOURNAL ARTICLE
P L Russo, A C Cheng, M Asghari-Jafarabadi, T Bucknall
BACKGROUND: Surveillance of healthcare associated infections (HAIs) in Australia is disparate, resource intensive, unsustainable and provides limited information. Traditional HAI surveillance is time intensive and agreement levels between clinicians has been shown to be variable. The aim was to compare two methods, a semi-automated algorithm, and coding data, against traditional surgical site infections (SSI) surveillance methods. METHODS: This retrospective multi-centre cohort study included all patients undergoing a hip (HPRO) or knee (KPRO) joint replacements and coronary artery bypass graft (CBGB) surgery over 2 years at 2 large metropolitan hospitals...
April 12, 2024: Journal of Hospital Infection
#4
JOURNAL ARTICLE
Marissa A Feldman, Anna Monica Agoston, Amanda N Burnside, Natacha D Emerson, Emily Mudd, Kate Z Koehn, Lauren E Gallanis
Since the onset of the COVID-19 pandemic, consultation/liaison (C/L) psychologists had to drastically shift their practices to care for psychiatrically acute pediatric patients admitted to medical settings. The aim of the current study was to provide an updated state of the field surrounding these changes and their implications for clinical practice. Psychologists and psychology post-doctoral fellows completed an anonymous, 51-item survey distributed via a national professional organization listserv. The results review responses, by percentages, about C/L team composition and practice patterns, as they relate to suicide risk assessments, transfers to inpatient psychiatric and other levels of care, intervention for boarding patients, and disposition and safety planning...
April 14, 2024: Journal of Clinical Psychology in Medical Settings
#5
JOURNAL ARTICLE
Abobakr Al-Amoodi, Derek Debicki, Osama Sefein, Daniel Bainbridge
OBJECTIVE: To investigate the frequency of stroke and code stroke activation and the factors influencing code stroke management in postoperative cardiac surgical patients. DESIGN: A retrospective quality improvement study was conducted between January 1, 2016, and December 31, 2021. SETTING: The Cardiac Surgery Recovery Unit (CSRU) at London Health Sciences Centre in London, Ontario, Canada. PARTICIPANTS: Postcardiac surgery patients aged 18 years or older who developed ischemic stroke during their admission to the CSRU...
March 12, 2024: Journal of Cardiothoracic and Vascular Anesthesia
#6
JOURNAL ARTICLE
Anthony Kayiira, Sarah McLaughlin, Jennifer Neda John, Daniel Zaake, Serena Xiong, Joyce Kambugu Balagadde, Veronica Gomez-Lobo, Henry Wabinga, Rahel Ghebre
Purpose: Although fertility preservation for patients with childhood and adolescent cancer is considered standard of care in the high-resource settings, it is rarely offered in low-resource settings. This study explores the experiences and perspectives of oncology health care professionals in Uganda to identify contextual barriers and facilitators to addressing oncofertility in low-resource settings. Methods: Using ground theory, we conducted in-depth face-to-face interviews of health care professionals managing pediatric patients at the Uganda Cancer Institute (UCI)...
April 13, 2024: Journal of Adolescent and Young Adult Oncology
#7
JOURNAL ARTICLE
Terri Elizabeth Workman, Joel Kupersmith, Phillip Ma, Christopher Spevak, Friedhelm Sandbrink, Yan Cheng, Qing Zeng-Treitler
Opioid use disorder is known to be under-coded as a diagnosis, yet problematic opioid use can be documented in clinical notes, which are included in electronic health records. We sought to identify problematic opioid use from a full range of clinical notes and compare the demographic and clinical characteristics of patients identified as having problematic opioid use exclusively in clinical notes to patients documented through ICD opioid use disorder diagnostic codes. We developed and applied a natural language processing (NLP) tool that combines rule-based pattern analysis and a trained support vector machine to the clinical notes of a patient cohort (n = 222,371) from two Veteran Affairs service regions to identify patients with problematic opioid use...
April 6, 2024: Healthcare (Basel, Switzerland)
#8
JOURNAL ARTICLE
John W Ambrose, Ken Catchpole, Heather L Evans, Lynne S Nemeth, Diana M Layne, Michelle Nichols
BACKGROUND: Resilience, in the field of Resilience Engineering, has been identified as the ability to maintain the safety and the performance of healthcare systems and is aligned with the resilience potentials of anticipation, monitoring, adaptation, and learning. In early 2020, the COVID-19 pandemic challenged the resilience of US healthcare systems due to the lack of equipment, supply interruptions, and a shortage of personnel. The purpose of this qualitative research was to describe resilience in the healthcare team during the COVID-19 pandemic with the healthcare team situated as a cognizant, singular source of knowledge and defined by its collective identity, purpose, competence, and actions, versus the resilience of an individual or an organization...
April 12, 2024: BMC Health Services Research
#9
JOURNAL ARTICLE
Olivia J Killeen, Lizbeth A Gonzalez, Amy E Rothberg, Sangeeta Khanna, Wayne T Cornblath, Tatiana Deveney, Sui H Wong, Lindsey B De Lott
BACKGROUND: Little is known about motivation for weight loss and barriers to weight loss among patients with idiopathic intracranial hypertension (IIH). Such information is crucial for developing tailored weight management recommendations and novel interventions. METHODS: We administered a survey to patients with IIH presenting to neuro-ophthalmology clinics at The University of Michigan Kellogg Eye Center (Michigan, USA) and St. Thomas' Hospital (London, England)...
April 12, 2024: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
#10
JOURNAL ARTICLE
Tsuyoshi Igami, Akihiro Maehigashi, Yoshihiko Nakamura, Yuichiro Hayashi, Masahiro Oda, Yukihiro Yokoyama, Takashi Mizuno, Junpei Yamaguchi, Shunsuke Onoe, Masaki Sunagawa, Nobuyuki Watanabe, Taisuke Baba, Shoji Kawakatsu, Kensaku Mori, Kazuhisa Miwa, Tomoki Ebata
PURPOSES: We performed a conversation analysis of the speech conducted among the surgical team during three-dimensional (3D)-printed liver model navigation for thrice or more repeated hepatectomy (TMRH). METHODS: Seventeen patients underwent 3D-printed liver navigation surgery for TMRH. After transcription of the utterances recorded during surgery, the transcribed utterances were coded by the utterer, utterance object, utterance content, sensor, and surgical process during conversation...
April 12, 2024: Surgery Today
#11
JOURNAL ARTICLE
Eui-Ryoung Han, Eun-Kyung Chung
Duty hour regulations (DHRs) were enforced in 2017 in Korea to prevent the detrimental effects of excessively prolonged working hours among medical residents. We investigated the adoption of and implications of the new DHRs among medical residents and faculty members. Semi-structured interviews were conducted with 15 medical residents and 9 faculty members across general surgery, internal medicine, obstetrics-gynecology, and pediatrics departments at Chonnam National University Hospital. Based on the constructivist grounded theory, we developed themes from the data by concurrent coding and analysis with theoretical sampling until data saturation...
2024: PloS One
#12
JOURNAL ARTICLE
Jeremy Singer, Julie A Marsh, David Menefee-Libey, Jacob Alonso, Dwuana Bradley, Hanora Tracy
Purpose: Nearly all schools in the United States closed in spring 2020, at the onset of the COVID-19 pandemic. We analyze traditional public and charter school reopenings for the 2020-21 school year in five urban districts. We provide a rich and theoretically grounded description of how and why educational leaders made reopening decisions in each of our case districts. Research Methods: We used data from a multiple-case study from March 2020 to July 2021. The research team conducted 56 interviews with school, district, and system-level leaders; triangulated with publicly available data; and also drew on interview data from a subsample of parents and guardians in each of our sites...
August 2023: Educational Administration Quarterly: EAQ
#13
JOURNAL ARTICLE
Jeff Walls, Karen Seashore Louis
Purpose: This study examines the sources and intensity of moral distress among school district leaders during the first full school year of the Covid-19 pandemic and investigates their coping mechanisms for addressing issues that create moral dilemmas for them. Design and Evidence: We draw on semi-structured interviews with 26 school district leaders across 13 school districts in the Northwestern United States. Brief summaries detailing themes in each interview were prepared. Magnitude coding was used to understand the intensity of district leaders' feelings of distress...
August 2023: Educational Administration Quarterly: EAQ
#14
REVIEW
Michael J Goldfarb, Martha Abshire Saylor, Biykem Bozkurt, Jillianne Code, Katherine E Di Palo, Angela Durante, Kristin Flanary, Ruth Masterson Creber, Modele O Ogunniyi, Fatima Rodriguez, Martha Gulati
Patient-centered care is gaining widespread acceptance by the medical and lay communities and is increasingly recognized as a goal of high-quality health care delivery. Patient-centered care is based on ethical principles and aims at establishing a partnership between the health care team and patient, family member, or both in the care planning and decision-making process. Patient-centered care involves providing respectful care by tailoring management decisions to patients' beliefs, preferences, and values...
April 11, 2024: Circulation
#15
JOURNAL ARTICLE
Nancy M Gell, Paula A Smith, Mariana Wingood
Introduction Mobile applications (apps) for exercise prescription may enhance communication between healthcare providers and patients while addressing common barriers to exercise among people with osteoarthritis. However, little is known about preferences and barriers to the use of mobile apps by physical therapists or people aging with osteoarthritis. Therefore, we aimed to examine physical therapist and patient perspectives on mobile apps to support physical therapist-prescribed home exercise for people with osteoarthritis...
March 2024: Curēus
#16
REVIEW
Stephanie Ballmann
After discharge of premature infants with complex care needs from the neonatal intensive care unit, a care gap arises due to the transition from inpatient to outpatient care. Consequences can be rehospitalization, revolving door effects, and high costs. Therefore, following hospitalization or inpatient rehabilitation, the patient is intended to transition to sociomedical aftercare. The legal basis for this is formed by § 43 paragraph 2 of the Fifth Book of the German Social Code (SGB V)...
April 10, 2024: Medizinische Klinik, Intensivmedizin und Notfallmedizin
#17
JOURNAL ARTICLE
Shaniece Criss, Melanie Kim, Monica M De La Cruz, Nhung Thai, Quynh C Nguyen, Thu T Nguyen
INTRODUCTION: Racism is a critical social determinant of health because it can have a direct impact on health and well-being, as well as infiltrate systems, policies, and practices. Few studies have explored the similarities and differences of experiences with racism and health between different minoritized groups. The objective of this paper is to examine how racism influences life experiences from the perspectives of Asian & Pacific Islander, Black, Latina, and Middle Eastern women...
April 15, 2024: Heliyon
#18
JOURNAL ARTICLE
Sarah Knight, Jill Rodda, Emma Tavender, Vicki Anderson, Natasha A Lannin, Adam Scheinberg
Background While goal setting with children and their families is considered best practice during rehabilitation following acquired brain injury, its successful implementation in an interdisciplinary team is not straightforward. This paper describes the application of a theoretical framework to understand factors influencing goal setting with children and their families in a large interdisciplinary rehabilitation team. Methods A semi-structured focus group was conducted with rehabilitation clinicians and those with lived experience of paediatric acquired brain injury (ABI)...
April 2024: Brain Impairment: a Multidisciplinary Journal of the Australian Society for the Study of Brain Impairment
#19
REVIEW
Cosmin M Banceu, Diana M Banceu, David S Kauvar, Adrian Popentiu, Vladimir Voth, Markus Liebrich, Marius Halic Neamtu, Marvin Oprean, Daiana Cristutiu, Marius Harpa, Klara Brinzaniuc, Horatiu Suciu
This work aims to provide a comprehensive description of the characteristics of a group of acute aortic diseases that are all potentially life-threatening and are collectively referred to as acute aortic syndromes (AASs). There have been recent developments in the care and diagnostic plan for AAS. A substantial clinical index of suspicion is required to identify AASs before irreversible fatal consequences arise because of their indefinite symptoms and physical indicators. A methodical approach to the diagnosis of AAS is addressed...
February 21, 2024: Journal of Clinical Medicine
#20
JOURNAL ARTICLE
Alida M Gertz, Michele Smith, Davon Thomas, Angeline Ti, Cheryl Vamos, Joe Bohn
BACKGROUND: Racism contributes to health disparities and is a serious threat to public health. Teaching physicians about racism, how to address it in medical practice, and developing high quality and sustainable curricula are essential to combating racism. OBJECTIVE: This study aimed to (1) describe the experience of racism and anti-racism teaching in residency programs, and elicit recommendations from key informants, and (2) use these data and formative research to develop recommendations for other residencies creating, implementing, and evaluating anti-racism curricula in their own programs...
April 8, 2024: BMC Medical Education
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