keyword
https://read.qxmd.com/read/38614726/appropriateness-of-the-use-of-ctpas-computed-tomographic-pulmonary-angiograms-in-suspected-pulmonary-embolisms
#21
JOURNAL ARTICLE
Thomas Dalia, Lakshmi Nijith, Alicia Enriquez, Munawer Al-Mudhaffar
No abstract text is available yet for this article.
November 2023: Clinical Medicine: Journal of the Royal College of Physicians of London
https://read.qxmd.com/read/38611955/development-of-paper-based-fluorescent-molecularly-imprinted-polymer-sensor-for-rapid-detection-of-lumpy-skin-disease-virus
#22
JOURNAL ARTICLE
Samr Kassem, Mervat E Hamdy, Karim M Selim, Dalia M A Elmasry, Momtaz A Shahein, Dalia M El-Husseini
Lumpy Skin Disease (LSD) is a notifiable viral disease caused by Lumpy Skin Disease virus (LSDV). It is usually associated with high economic losses, including a loss of productivity, infertility, and death. LSDV shares genetic and antigenic similarities with Sheep pox virus (SPV) and Goat pox (GPV) virus. Hence, the LSDV traditional diagnostic tools faced many limitations regarding sensitivity, specificity, and cross-reactivity. Herein, we fabricated a paper-based turn-on fluorescent Molecularly Imprinted Polymer (MIP) sensor for the rapid detection of LSDV...
April 8, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38611577/in-pursuit-of-optimal-quality-cultivar-specific-drying-approaches-for-medicinal-cannabis
#23
JOURNAL ARTICLE
Matan Birenboim, Nimrod Brikenstein, Danielle Duanis-Assaf, Dalia Maurer, Daniel Chalupowicz, David Kenigsbuch, Jakob A Shimshoni
A limited number of studies have examined how drying conditions affect the cannabinoid and terpene content in cannabis inflorescences. In the present study, we evaluated the potential of controlled atmosphere drying chambers for drying medicinal cannabis inflorescence. Controlled atmosphere drying chambers were found to reduce the drying and curing time by at least 60% compared to traditional drying methods, while preserving the volatile terpene content. On the other hand, inflorescences subjected to traditional drying were highly infested by Alternaria alternata and also revealed low infestation of Botrytis cinerea ...
April 8, 2024: Plants (Basel, Switzerland)
https://read.qxmd.com/read/38608280/proteome-wide-association-study-and-functional-validation-identify-novel-protein-markers-for-pancreatic-ductal-adenocarcinoma
#24
JOURNAL ARTICLE
Jingjing Zhu, Ke Wu, Shuai Liu, Alexandra Masca, Hua Zhong, Tai Yang, Dalia H Ghoneim, Praveen Surendran, Tanxin Liu, Qizhi Yao, Tao Liu, Sarah Fahle, Adam Butterworth, Md Ashad Alam, Jaydutt V Vadgama, Youping Deng, Hong-Wen Deng, Chong Wu, Yong Wu, Lang Wu
UNLABELLED: Pancreatic ductal adenocarcinoma (PDAC) remains a lethal malignancy, largely due to the paucity of reliable biomarkers for early detection and therapeutic targeting. Existing blood protein biomarkers for PDAC often suffer from replicability issues, arising from inherent limitations such as unmeasured confounding factors in conventional epidemiologic study designs. To circumvent these limitations, we use genetic instruments to identify proteins with genetically predicted levels to be associated with PDAC risk...
January 2, 2024: GigaScience
https://read.qxmd.com/read/38607809/an-artificial-intelligence-generated-model-predicts-90-day-survival-in-alcohol-associated-hepatitis-a-global-cohort-study
#25
JOURNAL ARTICLE
Winston Dunn, Yanming Li, Ashwani K Singal, Douglas A Simonetto, Luis A Díaz, Francisco Idalsoaga, Gustavo Ayares, Jorge Arnold, María Ayala-Valverde, Diego Perez, Jaime Gomez, Rodrigo Escarate, Eduardo Fuentes-López, Carolina Ramirez-Cadiz, Dalia Morales-Arraez, Wei Zhang, Steve Qian, Joseph C Ahn, Seth Buryska, Heer Mehta, Nicholas Dunn, Muhammad Waleed, Horia Stefanescu, Andreea Bumbu, Adelina Horhat, Bashar Attar, Rohit Agrawal, Joaquín Cabezas, Victor Echavaría, Berta Cuyàs, Maria Poca, German Soriano, Shiv K Sarin, Rakhi Maiwall, Prasun K Jalal, Fátima Higuera-de-la-Tijera, Anand V Kulkarni, P Nagaraja Rao, Patricia Guerra-Salazar, Lubomir Skladaný, Natália Kubánek, Veronica Prado, Ana Clemente-Sanchez, Diego Rincon, Tehseen Haider, Kristina R Chacko, Gustavo A Romero, Florencia D Pollarsky, Juan C Restrepo, Luis G Toro, Pamela Yaquich, Manuel Mendizabal, Maria L Garrido, Sebastián Marciano, Melisa Dirchwolf, Victor Vargas, César Jiménez, David Hudson, Guadalupe García-Tsao, Guillermo Ortiz, Juan G Abraldes, Patrick S Kamath, Marco Arrese, Vijay H Shah, Ramon Bataller, Juan P Arab
BACKGROUND AIMS: Alcohol-associated hepatitis (AH) poses significant short-term mortality. Existing prognostic models lack precision for 90-day mortality. Utilizing artificial intelligence (AI) in a global cohort, we sought to derive and validate an enhanced prognostic model. APPROACH AND RESULTS: The Global AlcHep initiative, a retrospective study across 23 centers in 12 countries, enrolled AH patients per NIAAA criteria. Centers were partitioned into derivation (11 centers, 860 patients) and validation cohorts (12 centers, 859 patients)...
April 12, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://read.qxmd.com/read/38607658/the-impact-of-poverty-and-socioeconomic-status-on-brain-behaviour-and-development-a-unified-framework
#26
REVIEW
Eid Abo Hamza, Richard Tindle, Simon Pawlak, Dalia Bedewy, Ahmed A Moustafa
In this article, we, for the first time, provide a comprehensive overview and unified framework of the impact of poverty and low socioeconomic status (SES) on the brain and behaviour. While there are many studies on the impact of low SES on the brain (including cortex, hippocampus, amygdala, and even neurotransmitters) and behaviours (including educational attainment, language development, development of psychopathological disorders), prior studies did not integrate behavioural, educational, and neural findings in one framework...
April 15, 2024: Reviews in the Neurosciences
https://read.qxmd.com/read/38607353/comparing-single-tooth-implant-placement-with-and-without-allogenic-soft-tissue-augmentation-a-randomized-clinical-trial
#27
JOURNAL ARTICLE
Sandra K Al-Tarawneh, Ghadeer Thalji, Mariana Fernandez Lozada, Dalia Waia, Lyndon F Cooper
OBJECTIVE: To explore the effect of adding an allogenic soft tissue graft at time of single implant placement using a fully digital workflow for single implant placement and restoration without making either analog or digital impressions. MATERIALS AND METHODS: A prospective randomized clinical study was performed enrolling thirtynine participants requiring single tooth implant randomized into (+ graft) group which received an allogenic dermal graft at the time of implant placement (n=19), or (- graft) group (n=20)...
April 5, 2024: International Journal of Oral & Maxillofacial Implants
https://read.qxmd.com/read/38595615/evaluation-of-prevalence-and-cause-of-endodontic-treatment-of-permanent-molars-in-10-year-old-children-of-riyadh-saudi-arabia
#28
JOURNAL ARTICLE
Dalia Alharthi, Reema K Abumelha, Deema M AlOjayen, Nouf S Alanezi, Reema M Aldakheel, Abdulaziz S Abumelha
The study aimed to assess the prevalence and cause of endodontic treatment in the first permanent molars of children aged ten in Saudi Arabia. Out of 824 children, 104 had dental caries, with a prevalence rate of 12.62%. The research revealed that the most involved teeth were mandibular left first molar, followed by mandibular right first molar, maxillary left first molar, and maxillary right first molar. Majority of patients had grossly decayed teeth, followed by caries, restorations, and endodontic treatment...
February 2024: Journal of Pharmacy & Bioallied Sciences
https://read.qxmd.com/read/38595182/understanding-preferences-for-receiving-health-communications-and-information-about-clinical-trials-a-cross-sectional-study-among-us-adults
#29
JOURNAL ARTICLE
Dalia Majumdar, Diane Webb, Stephanie Parsons, Elizabeth M Selwan-Lewis, Trisha Rettig, Emily Chastain, Winifred Obanor, Rob Birnberg, Amy Kuang
OBJECTIVE: Effective health communication is critical for understanding and acting on health information. This cross-sectional study explored participants' understanding of their health condition, their preferences for receiving health communications, and their interest in receiving clinical trial results across several therapeutic areas. METHODS: The study recruited participants via social media, email newsletters, and advocacy organizations. An online screener captured demographic information (health conditions, age, race/ethnicity, gender, and education)...
April 10, 2024: Current Medical Research and Opinion
https://read.qxmd.com/read/38594788/short-term-immunotoxicity-induced-by-florpyrauxifen-benzyl-herbicide-exposure-in-the-spleen-of-male-albino-mice
#30
JOURNAL ARTICLE
Dalia S Morsi, Hagar A Abu Quora, Hind S AboShabaan, Islam M El-Garawani, Ahmed E Abdel Moneim, Heba M R Hathout
Florpyrauxifen-benzyl (FPB) is a new arylpicolinate systemic herbicide that has been used to control or suppress the majority of herbicide-resistant biotype weeds in rice. To our knowledge, the impact of FPB on the immune system remains undetected thus far. Hence, this work aimed to address the toxic effects of FPB and the possible related mechanisms on the spleen of exposed mice. Initially, an acute toxicological test was performed to ascertain the median lethal dose (LD50 ) of FPB for 24 h which was found to be 371...
April 9, 2024: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://read.qxmd.com/read/38594696/a-portable-system-to-measure-knee-extensor-spasticity-after-spinal-cord-injury
#31
JOURNAL ARTICLE
Dalia De Santis, Monica A Perez
BACKGROUND: The pendulum test is a quantitative method used to assess knee extensor spasticity in humans with spinal cord injury (SCI). Yet, the clinical implementation of this method remains limited. The goal of our study was to develop an objective and portable system to assess knee extensor spasticity during the pendulum test using inertial measurement units (IMU). METHODS: Spasticity was quantified by measuring the first swing angle (FSA) using a 3-dimensional optical tracking system (with external markers over the iliotibial band, lateral knee epicondyle, and lateral malleolus) and two wireless IMUs (positioned over the iliotibial band and mid-part of the lower leg) as well as a clinical exam (Modified Ashworth Scale, MAS)...
April 9, 2024: Journal of Neuroengineering and Rehabilitation
https://read.qxmd.com/read/38582421/unveiling-the-capacity-of-bioaugmentation-application-in-comparison-with-biochar-and-rhamnolipid-for-tphs-degradation-in-aged-hydrocarbons-polluted-soil
#32
JOURNAL ARTICLE
Sandra Curiel-Alegre, Dalia de la Fuente-Vivas, Aqib Hassan Ali Khan, Javier García-Tojal, Blanca Velasco-Arroyo, Carlos Rumbo, Gerhard Soja, Carlos Rad, Rocío Barros
Persistent, aged hydrocarbons in soil hinder remediation, posing a significant environmental threat. While bioremediation offers an environmentally friendly and cost-effective approach, its efficacy for complex contaminants relies on enhancing pollutant bioavailability. This study explores the potential of immobilized bacterial consortia combined with biochar and rhamnolipids to accelerate bioremediation of aged total petroleum hydrocarbon (TPH)-contaminated soil. Previous research indicates that biochar and biosurfactants can increase bioremediation rates, while mixed consortia offer sequential degradation and higher hydrocarbon mineralization...
April 4, 2024: Environmental Research
https://read.qxmd.com/read/38582157/detection-and-characterisation-of-microplastics-in-tap-water-from-gauteng-south-africa
#33
JOURNAL ARTICLE
Gibbon Ramaremisa, Hlanganani Tutu, Dalia Saad
This study reports the presence, concentration, and characteristics of microplastics (MPs) in tap water in three suburbs in Gauteng Province in South Africa. Physical characterisation was conducted using stereomicroscopy and scanning electron microscopy following staining of MPs with the Rose Bengal dye. The concentrations of MPs in all samples ranged from 4.7 to 31 particles/L, with a mean of 14 ± 5.6 particles/L. Small-sized (<1 mm) and fibrous-shaped MPs were most abundant in all samples...
April 4, 2024: Chemosphere
https://read.qxmd.com/read/38581646/the-safe-addition-of-nitric-oxide-to-the-sweep-gas-of-the-extracorporeal-membrane-oxygenation-circuit-in-a-pediatric-cardiac-intensive-care-unit
#34
JOURNAL ARTICLE
Michael A Brock, Mohammed Ebraheem, Andrew Jaudon, Sukumar Suguna Narasimhulu, Zasha Vazquez-Colon, Joseph Philip, Dalia Lopez-Colon, Jeffrey P Jacobs, Mark S Bleiweis, Giles J Peek
Background: Nitric Oxide (NO) is a naturally occurring modulator of inflammation found in the human body. Several studies in the pediatric cardiothoracic surgery literature have demonstrated some beneficial clinical effects when NO is added to the sweep gas of the cardiopulmonary bypass circuit. Purpose: Our primary aim was to determine the safety of incorporating nitric oxide into the oxygenator sweep gas of the extracorporeal membrane oxygenation (ECMO) circuit. Secondarily, we looked at important clinical outcomes, such as survival, blood product utilization, and common complications related to ECMO...
April 6, 2024: Perfusion
https://read.qxmd.com/read/38580905/the-relationship-between-serum-astroglial-and-neuronal-markers-and-aqp4-and-mog-autoantibodies
#35
JOURNAL ARTICLE
Miyo K Chatanaka, Lisa M Avery, Maria D Pasic, Shanthan Sithravadivel, Dalia Rotstein, Catherine Demos, Rachel Cohen, Taron Gorham, Mingyue Wang, Martin Stengelin, Anu Mathew, George Sigal, Jacob Wohlstadter, Ioannis Prassas, Eleftherios P Diamandis
BACKGROUND: Certain demyelinating disorders, such as neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) exhibit serum autoantibodies against aquaporin-4 (αAQP4) and myelin oligodendrocyte glycoprotein (αMOG). The variability of the autoantibody presentation warrants further research into subtyping each case. METHODS: To elucidate the relationship between astroglial and neuronal protein concentrations in the peripheral circulation with occurrence of these autoantibodies, 86 serum samples were analyzed using immunoassays...
April 5, 2024: Clinical Proteomics
https://read.qxmd.com/read/38578238/strategies-for-inducing-and-validating-zinc-deficiency-and-zinc-repletion
#36
JOURNAL ARTICLE
Tara-Yesomi Wenegieme, Dalia Elased, Kelia E McMichael, Jananie Rockwood, Khanzada Hasrat, Adaku C Ume, Andrea G Marshall, Kit Neikirk, Annet Kirabo, Khalid M Elased, Antentor Hinton, Clintoria R Williams
Given the growing interest in the role of zinc in the onset and progression of diseases, there is a crucial demand for reliable methods to modulate zinc homeostasis. Using a dietary approach, we provide validated strategies to alter whole-body zinc in mice, applicable across species. For confirmation of zinc status, animal growth rates as well as plasma and urine zinc levels were evaluated. The accessible and cost-effective methodology outlined will increase scientific rigor, ensuring reproducibility in studies exploring the impact of zinc deficiency and repletion on the onset and progression of diseases...
April 5, 2024: American Journal of Physiology. Heart and Circulatory Physiology
https://read.qxmd.com/read/38571324/long-term-surgical-outcomes-of-one-muscle-vs-two-muscle-horizontal-strabismus-surgery
#37
JOURNAL ARTICLE
Hanadi A Ibrahim, Andre Slim, Dalia El Hadi, Christiane Al-Haddad
PURPOSE: While horizontal strabismus surgery is generally considered to have favorable outcomes, success rates can vary by type of procedure. Our purpose is to compare the long-term outcomes of patients who underwent one-muscle vs. two-muscle horizontal strabismus surgery. METHODS: This is a retrospective study comparing one-muscle to two-muscle strabismus surgery for small to moderate angle horizontal strabismus. Demographic data and eye exam parameters were compared at baseline and postoperatively (6 months up to 6 years)...
April 3, 2024: Strabismus
https://read.qxmd.com/read/38569334/advances-and-future-perspectives-of-water-defluoridation-by-adsorption-technology-a-review
#38
REVIEW
Noureddine El Messaoudi, Dison Stracke Pfingsten Franco, Sylwia Gubernat, Jordana Georgin, Zeynep Mine Şenol, Zeynep Ciğeroğlu, Dalia Allouss, Maryam El Hajam
Fluoride contamination in water sources poses a significant challenge to human health and the environment. In recent years, adsorption technology has emerged as a promising approach for water defluoridation due to its efficiency and cost-effectiveness. This review article comprehensively explores the advances in water defluoridation through adsorption processes. Various adsorbents, including natural and synthetic materials, have been investigated for their efficacy in removing fluoride ions from water. The mechanisms underlying adsorption interactions are elucidated, shedding light on the factors influencing defluoridation efficiency...
April 2, 2024: Environmental Research
https://read.qxmd.com/read/38568384/the-outcome-of-genetic-and-non-genetic-pediatric-cardiomyopathies
#39
JOURNAL ARTICLE
Ali AlAlakhfash, Luciano Agati, Giuseppe Mazzesi, Dalia Elhobi, Abdullah Alqwaiee, Khalid Alhory, Abdulrahman Almesned, Zuhair Alhasnan, Abdullah Alwadai
BACKGROUND: Pediatric cardiomyopathies (CMP) can be familial or idiopathic with increasing detection of genetic mutations. The study is a retrospective single-center review of cardiomyopathy patients from January 2011 to May 2020. Results of the genetic study, as well as the outcome, were reported. Patients were divided according to the type of CMP, age of presentation, and EF at presentation. Univariate and multivariate analysis and ROC and survival curves were done. RESULTS: We reported 229 patients under 14 years of age with a diagnosis of cardiomyopathy, most commonly DCM (160 patients (70%)) followed by HCM (26...
April 3, 2024: Egyptian Heart Journal: EHJ
https://read.qxmd.com/read/38568244/l-carnitine-decreases-myocardial-injury-in-children-undergoing-open-heart-surgery-a-randomized-controlled-trial
#40
JOURNAL ARTICLE
Wael El Feky, Dalia El-Afify, Dina Abdelhai, Mohamed Elkashlan, Ahmed Fakhreldin, Doaa El Amrousy
Myocardial injury in open-heart surgery is related to several factors including ischemia-reperfusion injury, generation of reactive oxygen species, increased production of inflammatory mediators, and enhancement of apoptosis of cardiomyocytes. The aim of this study was to study the effect of L-carnitine on myocardial injury in children undergoing open-heart surgery. This clinical trial was performed on 60 children with congenital heart disease (CHD) who underwent open-heart surgery. They were randomized into two groups: L-carnitine group who received L-carnitine 50 mg\kg\day once daily for 1 month before cardiac surgery and control group who received placebo for 1 month before cardiac surgery...
April 3, 2024: European Journal of Pediatrics
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