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https://www.readbyqxmd.com/read/28933937/changes-in-sugar-sweetened-soda-consumption-weight-and-waist-circumference-2-year-cohort-of-mexican-women
#1
Dalia Stern, Nicole Middaugh, Megan S Rice, Francine Laden, Ruy López-Ridaura, Bernard Rosner, Walter Willett, Martin Lajous
OBJECTIVES: To evaluate 2-year changes in soda consumption, weight, and waist circumference. METHODS: We followed 11 218 women from the Mexican Teachers' Cohort from 2006 to 2008. Dietary data were collected using a semiquantitative food frequency questionnaire. Weight was self-reported, and waist circumference was self-measured. We used linear regression to evaluate changes in sugar-sweetened and sugar-free soda consumption in relation to changes in weight and waist circumference, adjusting for lifestyle and other dietary factors...
September 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28932309/the-effect-of-three-different-biomaterials-on-proliferation-and-viability-of-human-dental-pulp-stem-cells-in-vitro-study
#2
Dalia A Mohamed, Maha I Abdelfattah, Eman H A Aboulezz
BACKGROUND: Biomaterial cytotoxicity on dental stem cells plays a critical role in managing the regeneration of dental tissue. AIM: The aim of the present study was to evaluate the effect of Nano-hydroxy apatite (NHA), Mineral trioxide aggregate (MTA), and Calcium-enriched mixture (CEM) on the proliferation, and viability of human dental pulp stem cells (hDPSCs) isolated from third molar teeth. METHODS: Cultured DPSCs were characterized and the tested biomaterials were shaped into cylinders then inserted directly on the DPSCs...
August 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28932163/preparedness-of-dammam-primary-health-care-centers-to-deal-with-emergency-cases
#3
Sanaa S M Alsaad, Salma H S Abu-Grain, Dalia Y M El-Kheir
OBJECTIVES: The objective of the study was to assess the availability of human and nonhuman resources for emergency medical services (EMSs) at the primary health care (PHC) level. MATERIALS AND METHODS: A cross-sectional study with mixed research methods (quantitative and qualitative) was carried out in governmental PHC centers in Dammam, Eastern Province of Saudi Arabia, between September 2014 and January 2015. Using systematic random sampling technique, 13 out of 26 PHC centers were included in the study...
September 2017: Journal of Family & Community Medicine
https://www.readbyqxmd.com/read/28930183/substituting-sodium-hydrosulfite-with-sodium-metabisulfite-improves-long-term-stability-of-a-distributable-paper-based-test-kit-for-point-of-care-screening-for-sickle-cell-anemia
#4
Kian Torabian, Dalia Lezzar, Nathaniel Z Piety, Alex George, Sergey S Shevkoplyas
Sickle cell anemia (SCA) is a genetic blood disorder that is particularly lethal in early childhood. Universal newborn screening programs and subsequent early treatment are known to drastically reduce under-five SCA mortality. However, in resource-limited settings, cost and infrastructure constraints limit the effectiveness of laboratory-based SCA screening programs. To address this limitation our laboratory previously developed a low-cost, equipment-free, point-of-care, paper-based SCA test. Here, we improved the stability and performance of the test by replacing sodium hydrosulfite (HS), a key reducing agent in the hemoglobin solubility buffer which is not stable in aqueous solutions, with sodium metabisulfite (MS)...
September 20, 2017: Biosensors
https://www.readbyqxmd.com/read/28926774/concurrent-administration-effect-of-antibiotic-and-anti-inflammatory-drugs-on-the-immunotoxicity-of-bacterial-endotoxins
#5
Azza M El Amir, Dalia G Tanious, Hanaa A Mansour
Pseudomonas aeruginosa (P. aeruginosa) is a gram-negative bacterium that causes a variety of diseases in compromised hosts. Bacterial endotoxins such as lipopolysaccharide (LPS) are the major outer surface membrane components that are present in almost all gram-negative bacteria and act as extremely strong stimulators of innate immunity and inflammation of the airway. This study was undertaken to determine the effect of combined administration of Gentamicin (GENT) as an antibiotic and Dexamethasone (DEXA) as an anti-inflammatory drug on some immunological and histological parameters...
September 16, 2017: International Immunopharmacology
https://www.readbyqxmd.com/read/28924336/intravitreal-injections-of-bevacizumab-the-impact-of-needle-size-in-intraocular-pressure-and-pain
#6
Mónica Loureiro, Rita Matos, Paula Sepulveda, Dália Meira
AIM: To compare the effect of 30-gauge vs 27-gauge needle size on intraocular pressure (IOP) rise and patients' pain experience after intravitreal injection (IVI) of bevacizumab. MATERIALS AND METHODS: Cross-sectional, randomized, double-armed study. Patients were randomized to IVI with 30-gauge or 27-gauge needle. The IOP was measured pre and post IVI. Patients' pain was graded using the visual analog scale (VAS). RESULTS: A total of 54 eyes were included...
May 2017: Journal of Current Glaucoma Practice
https://www.readbyqxmd.com/read/28910231/professionals-attitude-toward-reporting-child-sexual-abuse-in-saudi-arabia
#7
Dalia M Al-Saif, Majid Al-Eissa, Hassan Saleheen, Huda Al-Mutlaq, Mark D Everson, Maha A Almuneef
Child sexual abuse (CSA) requires specialized knowledge and training that includes forensic interview skills. The aim of this study was to determine variations in professionals' attitudes toward CSA by measuring three aspects of forensic attitudes (sensitivity, specificity, and skepticism) and evaluating disagreements concerning the assessment of CSA cases in Saudi Arabia. A cross-sectional, web-based study, in which the Child Forensic Attitude Scale was used to measure professionals' attitudes, was conducted...
September 14, 2017: Journal of Child Sexual Abuse
https://www.readbyqxmd.com/read/28900865/genetic-counseling-in-primary-immunodeficiency-disorders-an-emerging-experience-in-egypt
#8
Rabab E El Hawary, Safa S Meshaal, Dalia S Abd Elaziz, Marwa A Elsharkawy, Radwa S Alkady, Sohilla Lotfy, Ahmad El-Sheikhah, Amr Hassan, Nermeen M Galal, Jeannette A Boutros, Aisha M Elmarsafy
BACKGROUND: Primary immunodeficiency disorders (PIDs) are a heterogeneous group of diseases of the immune system leading to life-threatening infections, and, unless urgently treated with immune reconstitution, patients do not usually survive. With the continuing progress in molecular diagnosis, many mutations have been described in more than 300 genes. Genetic counseling has recently been considered an essential part of the management of PIDs. This study presents the experience of genetic counseling services in the largest PID center in Egypt, and reports on our management plan and the impact of prenatal diagnosis (PND) on families...
September 12, 2017: Molecular Diagnosis & Therapy
https://www.readbyqxmd.com/read/28898254/serum-levels-of-adiponectin-and-leptin-as-biomarkers-of-proteinuria-in-lupus-nephritis
#9
Valeria Diaz-Rizo, David Bonilla-Lara, Laura Gonzalez-Lopez, Dalia Sanchez-Mosco, Nicte S Fajardo-Robledo, Edsaul E Perez-Guerrero, N Alejandra Rodriguez-Jimenez, A Miriam Saldaña-Cruz, M Luisa Vazquez-Villegas, Eduardo Gomez-Bañuelos, Monica Vazquez-Del Mercado, E German Cardona-Muñoz, David Cardona-Muller, Xochitl Trujillo, Miguel Huerta, Mario Salazar-Paramo, Jorge I Gamez-Nava
INTRODUCTION: There are controversial results about the role of serum leptin and adiponectin levels as biomarkers of the severity of proteinuria in lupus nephritis. OBJECTIVE: The aim of this study was to evaluate the relationship between serum leptin and adiponectin levels with severity of proteinuria secondary to lupus nephritis (LN). METHODS: In a cross-sectional study, 103 women with systemic lupus erythematosus (SLE) were evaluated for kidney involvement...
2017: PloS One
https://www.readbyqxmd.com/read/28892900/immunohistochemical-expression-of-caspase-3-in-psoriasis
#10
Shaimaa M M Bebars, Dalia Rifaat Al-Sharaky, Mohammed A Gaber, Dina Ragab Afify
INTRODUCTION: Psoriasis is a persistent chronic immune-mediated, relapsing, inflammatory and hyper proliferative skin disorder with genetic predisposition. Psoriasis can be considered as a T-cell mediated disease, with a complex role for a variety of cytokine interaction between keratinocytes and T-lymphocytes. Caspase-3 is an enzyme that plays a key role in apoptosis; it is a member of the family of cysteinyle aspartate specific proteases. AIM: To evaluate the expression of caspase-3 in Egyptian psoriasis patients and its role in apoptosis of keratinocytes...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28888074/early-recovery-of-circulating-immature-b-cells-in-b-lymphoblastic-leukemia-patients-after-cd19-targeted-car-t-cell-therapy-a-pitfall-for-minimal-residual-disease-detection
#11
Wenbin Xiao, Dalia Salem, Catherine McCoy, Daniel Lee, Nirali N Shah, Maryalice Stetler-Stevenson, Constance M Yuan
BACKGROUND: CD19-targeted chimeric-antigen receptor-modified T-cells (CAR-T) are promising in the treatment of refractory B-lymphoblastic leukemia (B-ALL). Minimal residual disease (MRD) detection by multicolor flow cytometry (FCM) is critical to distinguish B-ALL MRD from regenerating, non-neoplastic B-cell populations. METHODS: FCM was performed on samples from 9 patients with B-ALL treated with CAR-T. RESULTS: All 9 patients showed response to CAR-T...
September 9, 2017: Cytometry. Part B, Clinical Cytometry
https://www.readbyqxmd.com/read/28875530/the-revised-basel-statements-on-the-future-of-hospital-pharmacy-what-do-they-mean-for-saudi-arabia
#12
Hanadi Al Sabban, Ahmed Al-Jedai, Dalia Bajis, Jonathan Penm
OBJECTIVES: To describe the current hospital pharmacy practice in Saudi Arabia according to the revised Basel statements. METHODS: A review of the available data based on published literature in the subject area was carried out. KEY FINDINGS: The original Basel Statements were developed at the 2008 Global Conference on the Future of Hospital Pharmacy in Basel, Switzerland. Representatives from 98 countries, including Saudi Arabia, attended this conference...
September 6, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28874781/immunization-of-cervidized-transgenic-mice-with-multimeric-deer-prion-protein-induces-self-antibodies-that-antagonize-chronic-wasting-disease-infectivity-in-vitro
#13
Dalia H Abdelaziz, Simrika Thapa, Basant Abdulrahman, Li Lu, Shikha Jain, Hermann M Schatzl
Chronic wasting disease (CWD) is the most contagious prion disease. It is expanding rapidly in North America, was found recently in Europe, and the potential for transmission to humans cannot be excluded yet. We hypothesized that it is possible to prevent peripheral CWD infection and CWD prion shedding by inducing auto-antibodies against the cellular prion protein (PrP(C)) by active vaccination. Our objective is to overcome self-tolerance against PrP by using a multimeric recombinant PrP (recPrP) as an immunogen...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28871831/identification-of-some-novel-xanthine-based-derivatives-with-bronchodilator-activity
#14
Abdalla R Mohamed, Hanan H Georgey, Riham F George, Wafaa I El-Eraky, Dalia O Saleh, Nagwa M Abdel Gawad
AIM: The discovery of new bronchodilators with higher efficacy than theophylline is an important issue for asthmatic patients. MATERIALS & METHODS: Theophylline 2, 8-bromotheophylline 4 and theobromine 6 were reacted with different 2/3-chloro-N-phenylacetamides 1a-d or their propanamide analogs 1e-g to obtain 3a-g, 5a-g and 7a-g, respectively. The target compounds were screened for their in vitro bronchodilator activity using isolated guinea pig tracheal rings precontracted with histamine and compared with their precursors...
September 5, 2017: Future Medicinal Chemistry
https://www.readbyqxmd.com/read/28865259/current-margin-practice-and-effect-on-re-excision-rates-following-the-publication-of-the-sso-astro-consensus-and-abs-consensus-guidelines-a-national-prospective-study-of-2858-women-undergoing-breast-conserving-therapy-in-the-uk-and-ireland
#15
Sarah Shuk-Kay Tang, Sarantos Kaptanis, James B Haddow, Giuseppina Mondani, Beatrix Elsberger, Marios Konstantinos Tasoulis, Christine Obondo, Neil Johns, Wisam Ismail, Asim Syed, Panayioti Kissias, Mary Venn, Souganthy Sundaramoorthy, Gareth Irwin, Amtul S Sami, Dalia Elfadl, Alice Baggaley, Dionysios Dennis Remoundos, Fiona Langlands, Petros Charalampoudis, Zoe Barber, Werbena L S Hamilton-Burke, Ayesha Khan, Chiara Sirianni, Louise Anne-Marie Grant Merker, Sunita Saha, Risha Arun Lane, Sharat Chopra, Sophie Dupré, Aiden T Manning, Edward R St John, Aya Musbahi, Nokwanda Dlamini, Caitlin L McArdle, Chloe Wright, James O Murphy, Ravi Aggarwal, Matei Dordea, Karen Bosch, Donna Egbeare, Hisham Osman, Salim Tayeh, Faraz Razi, Javeria Iqbal, Serena F C Ledwidge, Vanessa Albert
INTRODUCTION: There is variation in margin policy for breast conserving therapy (BCT) in the UK and Ireland. In response to the Society of Surgical Oncology and American Society for Radiation Oncology (SSO-ASTRO) margin consensus ('no ink on tumour' for invasive and 2 mm for ductal carcinoma in situ [DCIS]) and the Association of Breast Surgery (ABS) consensus (1 mm for invasive and DCIS), we report on current margin practice and unit infrastructure in the UK and Ireland and describe how these factors impact on re-excision rates...
August 29, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28853738/erratum-the-eed-protein-protein-interaction-inhibitor-a-395-inactivates-the-prc2-complex
#16
Yupeng He, Sujatha Selvaraju, Michael L Curtin, Clarissa G Jakob, Haizhong Zhu, Kenneth M Comess, Bailin Shaw, Juliana The, Evelyne Lima-Fernandes, Magdalena M Szewczyk, Dong Cheng, Kelly L Klinge, Huan-Qiu Li, Marina Pliushchev, Mikkel A Algire, David Maag, Jun Guo, Justin Dietrich, Sanjay C Panchal, Andrew M Petros, Ramzi F Sweis, Maricel Torrent, Lance J Bigelow, Guillermo Senisterra, Fengling Li, Steven Kennedy, Qin Wu, Donald J Osterling, David J Lindley, Wenqing Gao, Scott Galasinski, Dalia Barsyte-Lovejoy, Masoud Vedadi, Fritz G Buchanan, Cheryl H Arrowsmith, Gary G Chiang, Chaohong Sun, William N Pappano
No abstract text is available yet for this article.
July 18, 2017: Nature Chemical Biology
https://www.readbyqxmd.com/read/28853129/patients-attitudes-and-perceptions-regarding-research-and-their-rights-a-pilot-survey-study-from-the-middle-east
#17
Tamer Hifnawy, Samer Kobrosly, Hillary Edwards, Manal Anwar, Dalia Zahran, Henry Silverman
Ethical and regulatory oversight of research may be suboptimal in low- and middle-income countries. To determine patients' attitudes and perceptions toward research participation and perceptions of their rights, we recruited 202 participants from hospitals in Egypt, Lebanon, Saudi Arabia and Sudan and asked them to complete a questionnaire assessing attitudes and perceptions. Around 20% believed that doctors sometimes perform research on patients without their knowledge and 35% believed that if participants withdrew from the research they would not receive good medical care...
August 27, 2017: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/28851905/honey-based-hydrogel-in-vitro-and-comparative-in-vivo-evaluation-for-burn-wound-healing
#18
Reham F El-Kased, Reham I Amer, Dalia Attia, M M Elmazar
Honey was used to treat wounds since ancient times till nowadays. The present study aimed at preparing a honey-based hydrogel and assay its antimicrobial properties and wound healing activity; in-vitro and in-vivo. Topical honey hydrogel formulations were prepared using three honey concentrations with gelling agents; chitosan and carbopol 934. The prepared formulae were evaluated for pH, spreadability, swelling index, in-vitro release and antimicrobial activity. The pH and spreadability were in the range of 4...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28851334/piloting-a-low-cost-hardware-intervention-to-reduce-improper-disposal-of-solid-waste-in-communal-toilets-in-low-income-settlements-in-dhaka-bangladesh
#19
Farzana Yeasmin, Stephen P Luby, Ronald E Saxton, Fosiul A Nizame, Mahbub-Ul Alam, Notan Chandra Dutta, Abdullah-Al Masud, Dalia Yeasmin, Anita Layden, Habibur Rahman, Rachel Abbott, Leanne Unicomb, Peter J Winch
BACKGROUND: Bangladesh faces daunting challenges in addressing the sanitation needs of its urban poor. Maintaining the cleanliness and functionality of communal toilets is dependent upon periodic emptying of fecal sludge, and cooperation between users of communal toilets. Trash disposal into latrines can block the outflow pipes, rendering the toilets non-functional. METHODS: Pre-intervention: We conducted in-depth interviews with five operators of fecal sludge emptying equipment and five adult residents who were also caregivers of children...
August 29, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28845128/clinical-characteristics-and-long-term-survival-differences-of-the-anca-associated-vasculitis-group-a-cross-sectional-study-of-27-patients
#20
Jolanta Dadonienė, Gintarė Kumžaitė, Rimvydė Mačiulytė, Dalia Miltinienė
OBJECTIVE: The goal of this study was to describe long-term patient survival and possible prognostic factors of a group of patients diagnosed with granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) hospitalized at the tertiary Rheumatology Centre in Vilnius. MATERIAL AND METHODS: A cross-sectional study of 27 patients hospitalized at the Rheumatology Centre of Santaros klinikos of Vilnius University Hospital from 1 January 2001 to 31 December 2015 with diagnoses of GPA and MPA were carried out...
2017: Acta medica Lituanica
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