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JOURNAL ARTICLE
Chirayu Mohindroo, Seyda Baydogan, Parul Agarwal, Robin D Wright, Laura R Prakash, Maureen E Mork, Alison P Klein, Daniel A Laheru, Jessica E Maxwell, Matthew H G Katz, Arvind Dasari, Michael P Kim, Jin He, Florencia McAllister, Ana De Jesus-Acosta
10% of pancreatic neuroendocrine tumors (pNETs) are related to inherited syndromes (MEN1, MEN4, VHL, NF1, TSC). Growing evidence suggests that clinically sporadic pNETs can also harbor germline pathogenic variants. In this study, we report the prevalence of pathological/likely pathological germline variants (P/LP) in a high-risk cohort and an unselected cohort. We collected clinical data of patients with pNETs seen at MD Anderson Cancer Center (MDACC) and Johns Hopkins Hospital (JHH). High-risk cohort included (n=132) patients seen at MDACC who underwent germline testing for high-risk criteria (early onset, personal or family history of cancer and syndromic features) between 2013-2019...
April 25, 2024: Cancer Prevention Research
#2
JOURNAL ARTICLE
Carliane Maria Guimarães Alves, Raimundo Rosemiro de Jesus Baia, Amanda Mendes Pacheco, Abthyllane Amaral de Carvalho, Vitor Araújo Farias, Marcela Nunes Videira, Francisco Célio Maia Chagas, Eliane Tie Oba Yoshioka, Marcos Tavares-Dias
PURPOSE: This study investigated the anthelmintic efficacy of therapeutic baths with the essential oil of Piper marginatum Jacq against the monogeneans Anacanthorus spathulatus Kritsky, Thatcher & Kayton, 1979, Notozothecium janauachensis Belmont-Jégu, Domingues & Laterça 2004, Mymarothecium boegeri Cohen & Kohn, 2005 and Linguadactyloides brinkmanni Thatcher & Krytsky, 1983 in Colossoma macropomum Cuvier, 1818, and its hematological and histopathological effects on this fish...
April 25, 2024: Acta Parasitologica
#3
JOURNAL ARTICLE
Alexandre R Zuntini, Tom Carruthers, Olivier Maurin, Paul C Bailey, Kevin Leempoel, Grace E Brewer, Niroshini Epitawalage, Elaine Françoso, Berta Gallego-Paramo, Catherine McGinnie, Raquel Negrão, Shyamali R Roy, Lalita Simpson, Eduardo Toledo Romero, Vanessa M A Barber, Laura Botigué, James J Clarkson, Robyn S Cowan, Steven Dodsworth, Matthew G Johnson, Jan T Kim, Lisa Pokorny, Norman J Wickett, Guilherme M Antar, Lucinda DeBolt, Karime Gutierrez, Kasper P Hendriks, Alina Hoewener, Ai-Qun Hu, Elizabeth M Joyce, Izai A B S Kikuchi, Isabel Larridon, Drew A Larson, Elton John de Lírio, Jing-Xia Liu, Panagiota Malakasi, Natalia A S Przelomska, Toral Shah, Juan Viruel, Theodore R Allnutt, Gabriel K Ameka, Rose L Andrew, Marc S Appelhans, Montserrat Arista, María Jesús Ariza, Juan Arroyo, Watchara Arthan, Julien B Bachelier, C Donovan Bailey, Helen F Barnes, Matthew D Barrett, Russell L Barrett, Randall J Bayer, Michael J Bayly, Ed Biffin, Nicky Biggs, Joanne L Birch, Diego Bogarín, Renata Borosova, Alexander M C Bowles, Peter C Boyce, Gemma L C Bramley, Marie Briggs, Linda Broadhurst, Gillian K Brown, Jeremy J Bruhl, Anne Bruneau, Sven Buerki, Edie Burns, Margaret Byrne, Stuart Cable, Ainsley Calladine, Martin W Callmander, Ángela Cano, David J Cantrill, Warren M Cardinal-McTeague, Mónica M Carlsen, Abigail J A Carruthers, Alejandra de Castro Mateo, Mark W Chase, Lars W Chatrou, Martin Cheek, Shilin Chen, Maarten J M Christenhusz, Pascal-Antoine Christin, Mark A Clements, Skye C Coffey, John G Conran, Xavier Cornejo, Thomas L P Couvreur, Ian D Cowie, Laszlo Csiba, Iain Darbyshire, Gerrit Davidse, Nina M J Davies, Aaron P Davis, Kor-Jent van Dijk, Stephen R Downie, Marco F Duretto, Melvin R Duvall, Sara L Edwards, Urs Eggli, Roy H J Erkens, Marcial Escudero, Manuel de la Estrella, Federico Fabriani, Michael F Fay, Paola de L Ferreira, Sarah Z Ficinski, Rachael M Fowler, Sue Frisby, Lin Fu, Tim Fulcher, Mercè Galbany-Casals, Elliot M Gardner, Dmitry A German, Augusto Giaretta, Marc Gibernau, Lynn J Gillespie, Cynthia C González, David J Goyder, Sean W Graham, Aurélie Grall, Laura Green, Bee F Gunn, Diego G Gutiérrez, Jan Hackel, Thomas Haevermans, Anna Haigh, Jocelyn C Hall, Tony Hall, Melissa J Harrison, Sebastian A Hatt, Oriane Hidalgo, Trevor R Hodkinson, Gareth D Holmes, Helen C F Hopkins, Christopher J Jackson, Shelley A James, Richard W Jobson, Gudrun Kadereit, Imalka M Kahandawala, Kent Kainulainen, Masahiro Kato, Elizabeth A Kellogg, Graham J King, Beata Klejevskaja, Bente B Klitgaard, Ronell R Klopper, Sandra Knapp, Marcus A Koch, James H Leebens-Mack, Frederic Lens, Christine J Leon, Étienne Léveillé-Bourret, Gwilym P Lewis, De-Zhu Li, Lan Li, Sigrid Liede-Schumann, Tatyana Livshultz, David Lorence, Meng Lu, Patricia Lu-Irving, Jaquelini Luber, Eve J Lucas, Manuel Luján, Mabel Lum, Terry D Macfarlane, Carlos Magdalena, Vidal F Mansano, Lizo E Masters, Simon J Mayo, Kristina McColl, Angela J McDonnell, Andrew E McDougall, Todd G B McLay, Hannah McPherson, Rosa I Meneses, Vincent S F T Merckx, Fabián A Michelangeli, John D Mitchell, Alexandre K Monro, Michael J Moore, Taryn L Mueller, Klaus Mummenhoff, Jérôme Munzinger, Priscilla Muriel, Daniel J Murphy, Katharina Nargar, Lars Nauheimer, Francis J Nge, Reto Nyffeler, Andrés Orejuela, Edgardo M Ortiz, Luis Palazzesi, Ariane Luna Peixoto, Susan K Pell, Jaume Pellicer, Darin S Penneys, Oscar A Perez-Escobar, Claes Persson, Marc Pignal, Yohan Pillon, José R Pirani, Gregory M Plunkett, Robyn F Powell, Ghillean T Prance, Carmen Puglisi, Ming Qin, Richard K Rabeler, Paul E J Rees, Matthew Renner, Eric H Roalson, Michele Rodda, Zachary S Rogers, Saba Rokni, Rolf Rutishauser, Miguel F de Salas, Hanno Schaefer, Rowan J Schley, Alexander Schmidt-Lebuhn, Alison Shapcott, Ihsan Al-Shehbaz, Kelly A Shepherd, Mark P Simmons, André O Simões, Ana Rita G Simões, Michelle Siros, Eric C Smidt, James F Smith, Neil Snow, Douglas E Soltis, Pamela S Soltis, Robert J Soreng, Cynthia A Sothers, Julian R Starr, Peter F Stevens, Shannon C K Straub, Lena Struwe, Jennifer M Taylor, Ian R H Telford, Andrew H Thornhill, Ifeanna Tooth, Anna Trias-Blasi, Frank Udovicic, Timothy M A Utteridge, Jose C Del Valle, G Anthony Verboom, Helen P Vonow, Maria S Vorontsova, Jurriaan M de Vos, Noor Al-Wattar, Michelle Waycott, Cassiano A D Welker, Adam J White, Jan J Wieringa, Luis T Williamson, Trevor C Wilson, Sin Yeng Wong, Lisa A Woods, Roseina Woods, Stuart Worboys, Martin Xanthos, Ya Yang, Yu-Xiao Zhang, Meng-Yuan Zhou, Sue Zmarzty, Fernando O Zuloaga, Alexandre Antonelli, Sidonie Bellot, Darren M Crayn, Olwen M Grace, Paul J Kersey, Ilia J Leitch, Hervé Sauquet, Stephen A Smith, Wolf L Eiserhardt, Félix Forest, William J Baker
Angiosperms are the cornerstone of most terrestrial ecosystems and human livelihoods1,2 . A robust understanding of angiosperm evolution is required to explain their rise to ecological dominance. So far, the angiosperm tree of life has been determined primarily by means of analyses of the plastid genome3,4 . Many studies have drawn on this foundational work, such as classification and first insights into angiosperm diversification since their Mesozoic origins5-7 . However, the limited and biased sampling of both taxa and genomes undermines confidence in the tree and its implications...
April 24, 2024: Nature
#4
JOURNAL ARTICLE
Daniel Rojas-Valverde, Renan Stocco de Camargo, Juan Calleja-González, Jesús Muñoz-Jiménez, Marcelo Tuesta, Sameer Badri Al-Mhanna, Tim N Ziegenfuss, Roberto Cannataro, Diego A Bonilla
No abstract text is available yet for this article.
April 24, 2024: Cannabis and Cannabinoid Research
#5
JOURNAL ARTICLE
Paulo Sérgio M Ferreira, Thiago Gonçalves-Souza, Lilian S Ouchi-Melo, Ary T Oliveira-Filho, Maria Jesus N Rodal
Here we studied the entire Atlantic Forest hotspot to investigate whether the effect of different environmental predictors depends on the phylogenetic extension and the biogeographical history of different Atlantic Forest sectors. We used occurrence data of 3,183 plant species with arboreal or arborescent habits. We reconstructed climatic stability across 120,000 years using the Random Forest method. Then, we compared the effect of biogeographical history, topographic, and climatic variables on species richness and phylogenetic diversity using Geographically Weighted Regression (GWR) models...
2024: Anais da Academia Brasileira de Ciências
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JOURNAL ARTICLE
Carlos Martins Neto, Fábio Nogueira da Silva, José de Jesus Dias Júnior, Maria Dos Remédios Freitas Carvalho Branco, Alcione Miranda Dos Santos, Bruno Luciano Carneiro Alves de Oliveira
OBJECTIVE: To analyze the influence of individual and contextual factors of the hospital and the municipality of care on the survival of patients with Severe Acute Respiratory Syndrome due to COVID-19. METHODS: Hospital cohort study with data from 159,948 adults and elderly with Severe Acute Respiratory Syndrome due to COVID-19 hospitalized from January 1 to December 31, 2022 and reported in the Influenza Epidemiological Surveillance Information System. The contextual variables were related to the structure, professionals and equipment of the hospital establishments and socioeconomic and health indicators of the municipalities...
2024: Brazilian Journal of Epidemiology
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JOURNAL ARTICLE
Karine Lino Rodrigues, Patrícia de Oliveira da Silva Scaranni, Evelyn Nunes Goulart da Silva Pereira, Vivian Vieira Dias da Silva, Raquel Rangel Silvares, Beatriz Peres de Araujo, Cristina Castilho, Maria Inês Schmidt, Maria de Jesus Mendes da Fonseca, Rosane Harter Griep, Anissa Daliry
INTRODUCTION: Hair cortisol level has recently been identified as a promising marker for detecting long-term cortisol levels and a marker of hypothalamic-pituitary-adrenal cortex (HPA) axis activity. However, research on the association between obesity and an altered cortisol metabolism remains controversial. OBJECTIVE: This study aimed to investigate the relationship between hair cortisol levels and overweight and obesity in participants from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)...
2024: Frontiers in Endocrinology
#8
Octavio Herrera, Maria V Rodriguez, Manuel R De Jesus, Alexis Garza, Henry Ruiz
Twiddler's syndrome is the voluntary or involuntary manipulation of an implanted device, most described in cardiac literature. Lead coiling may result in device malfunction due to lead migration or, less commonly, lead fracture. There are few but increasing reports of Twiddler's syndrome resulting in lead migration in sacral neuromodulation, but lead fracture has not yet been described. A 57-year-old Latina female presented with fecal incontinence and refractory overactive bladder. She underwent successful implantation of a sacral neuromodulation device with the resolution of symptoms...
March 2024: Curēus
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JOURNAL ARTICLE
Susana Monge, James Humphreys, Nathalie Nicolay, Toon Braeye, Izaak Van Evercooren, Christian Holm Hansen, Hanne-Dorthe Emborg, Chiara Sacco, Alberto Mateo-Urdiales, Jesús Castilla, Iván Martínez-Baz, Brechje de Gier, Susan Hahné, Hinta Meijerink, Anja Bråthen Kristoffersen, Ausenda Machado, Patricia Soares, Anthony Nardone, Sabrina Bacci, Esther Kissling, Baltazar Nunes
Using a common protocol across seven countries in the European Union/European Economic Area, we estimated XBB.1.5 monovalent vaccine effectiveness (VE) against COVID-19 hospitalisation and death in booster-eligible ≥ 65-year-olds, during October-November 2023. We linked electronic records to construct retrospective cohorts and used Cox models to estimate adjusted hazard ratios and derive VE. VE for COVID-19 hospitalisation and death was, respectively, 67% (95%CI: 58-74) and 67% (95%CI: 42-81) in 65- to 79-year-olds and 66% (95%CI: 57-73) and 72% (95%CI: 51-85) in ≥ 80-year-olds...
April 2024: Influenza and Other Respiratory Viruses
#10
JOURNAL ARTICLE
Maribel Domingues Carvalhais, Andrea Raquel Melo Oliveira, Paula Cristina Ferreira Fontoura, Catarina Sousa Soares, Bruna Filipa Conceição Pinho, Ana Catarina Lopes Beirão Fernandes, Vanessa Silva Azevedo, Sónia Catarina Silva Santos, Mariana Isabel Tavares Fernandes, Isabel de Jesus Oliveira
PURPOSE: To assess hospitalized children's satisfaction with nursing care. DESIGN AND METHODS: Cross-sectional study using the "Children Care Quality at Hospital" questionnaire. 61 children admitted to the Pediatrics Department of a hospital in the Northern Region of Portugal were enrolled. RESULTS: The ranged age of the participants was 6 to 15 (10,61 ± 2,66 years), and most were male (52.46%; n = 32). The mean score in the three domains was 128 (77...
April 22, 2024: Journal of Pediatric Nursing
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JOURNAL ARTICLE
Kader Cetin Gedik, Ana M Ortega-Villa, Grace Materne, Andre Rastegar, Gina A Montealegre Sanchez, Adam Reinhardt, Paul A Brogan, Yackov Berkun, Sara Murias, Maria Robles, Susanne Schalm, Adriana A de Jesus, Raphaela Goldbach-Mansky
OBJECTIVES: Patients with chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature/proteasome-associated autoinflammatory syndrome (CANDLE/PRAAS) respond to the janus kinase inhibitor 1/2 inhibition with baricitinib at exposures higher than in rheumatoid arthritis. Baricitinib dose reductions to minimise exposure triggered disease flares which we used to develop 'flare criteria'. METHODS: Of 10 patients with CANDLE/PRAAS treated with baricitinib in an open-label expanded-access programme, baricitinib doses were reduced 14 times in 9 patients between April 2014 and December 2019...
April 23, 2024: Annals of the Rheumatic Diseases
#12
JOURNAL ARTICLE
Maria Galvez-Llompart, Jesús Hierrezuelo, Mariluz Blasco, Riccardo Zanni, Jorge Galvez, Antonio de Vicente, Alejandro Pérez-García, Diego Romero
Antimicrobial resistance (AMR) is a pressing global issue exacerbated by the abuse of antibiotics and the formation of bacterial biofilms, which cause up to 80% of human bacterial infections. This study presents a computational strategy to address AMR by developing three novel quantitative structure-activity relationship (QSAR) models based on molecular topology to identify potential anti-biofilm and antibacterial agents. The models aim to determine the chemo-topological pattern of Gram (+) antibacterial, Gram (-) antibacterial, and biofilm formation inhibition activity...
December 2024: Journal of Enzyme Inhibition and Medicinal Chemistry
#13
REVIEW
América Patricia Pontigo-Loyola, Martha Mendoza-Rodriguez, Rubén de la Rosa-Santillana, Maria Gracia Rivera-Pacheco, Horacio Islas-Granillo, Juan Fernando Casanova-Rosado, María de Lourdes Márquez-Corona, José de Jesús Navarrete-Hernández, Carlo Eduardo Medina-Solís, David J Manton
The maintenance of oral health is a crucial aspect of general well-being; however, a significant proportion of the worldwide population experiences a range of oral diseases. Dental caries is a highly prevalent non-communicable disease globally, especially in children and adolescents. Fluoride is involved in the control of dental caries, primarily by decreasing the critical pH for dental hard tissue dissolution and decreasing enamel solubility. Due to the substantial data supporting the efficacy of fluoride in controlling dental caries, many community-level fluoridation initiatives have been devised and executed as global public health preventive interventions...
March 27, 2024: Pediatric Reports
#14
JOURNAL ARTICLE
Andressa Silva Costa, José de Ribamar Macedo Costa, Ana Vladia Bandeira Moreira, Marcelino Santos Neto, Virlane Kelly Lima Hunaldo, Floriacy Stabnow Santos, Márcio Flávio Moura de Araújo, Ana Cristina Pereira de Jesus Costa
Aim: To assess the effect of cashew nut flour on the hematological parameters of children living with HIV-AIDS. Method: A 32-week randomized, blind clinical trial conducted at a specialized outpatient clinic. Children aged 2-12 years were allocated to intervention groups (IGs) ( n = 11) receiving 12 g/day of cashew nut flour and control groups (CGs) ( n = 9) receiving 12 g/day of carboxymethyl cellulose. Parameters of erythrocytes, leukocytes, platelets, and lipid profiles were evaluated...
April 23, 2024: Nutrition and Health
#15
Alejandra G Martinez-Perez, Rodolfo Garza-Morales, Maria J de Loera-Arias, Sheila A Villa-Cedillo, Aracely Garcia-Garcia, Humberto Rodriguez-Rocha, Orlando E Flores-Maldonado, Jesus Valdes, Jose J Perez-Trujillo, Odila Saucedo-Cardenas
No abstract text is available yet for this article.
April 22, 2024: Molecular Biology Reports
#16
JOURNAL ARTICLE
Victoria Jiménez Carretero, Ninfa Liccardi, Maria Arribas Tejedor, Ricardo de Pascual, Jorge Hernández Campano, Jesús M Hernández-Guijo
The present work, using chromaffin cells of bovine adrenal medullae (BCCs), aims to describe what type of ionic current alterations induced by lead (Pb2+ ) underlies its effects reported on synaptic transmission. We observed that the acute application of Pb2+ lead to a drastic depression of neurotransmitters release in a concentration-dependent manner when the cells were stimulated with both K+ or acetylcholine, with an IC50 of 119,57 μM and of 5,19 μM, respectively. This effect was fully recovered after washout...
April 20, 2024: Toxicology
#17
JOURNAL ARTICLE
Jing Zhou, Jing Gong, Lorna Kwai Ping Suen, Binxu Yang, Xia Zhang, Shun Chan, David Hali De Jesus, Jin Tang
METHODS: This cross-sectional study sampled 833 nurses from 2 new hospitals in Guizhou Province, China. They completed a questionnaire on entrepreneurial leadership, nursing team creativity, innovation climate, creative self-efficacy, team psychological safety, and knowledge sharing. Data were analyzed using structural equation modeling. RESULTS: Entrepreneurial leadership positively influenced nursing team creativity. Innovation climate, creative self-efficacy, team psychological safety, and knowledge sharing mediated the relationship between entrepreneurial leadership and nursing team creativity in new hospitals...
May 1, 2024: Journal of Nursing Administration
#18
JOURNAL ARTICLE
Ernesto Pérez-Sánchez, Raúl Montiel-Cruz, Eréndira Romero-Domínguez, Griselda Pascacio-Bermúdez, Arturo Báez-Hernández, Guadalupe Díaz Del Castillo-Flores, Fabián Correa-Morales, Gonzalo Vázquez-Prokopec, Pablo Manrique-Saide, Azael Che-Mendoza, Gabriela Meneses-Ruiz, Irma López-Martínez, María Jesús Sánchez
Introduction. In 2021, the Secretaría de Salud de México and the Pan American Health Organization launched an initiative to interrupt intra-domiciliary vector transmission of Trypanosoma cruzi based on the prevalence of Chagas disease in children. The Mexican State of Veracruz was leading this initiative. Objective. To estimate the seroprevalence of T. cruzi infection among children under 15 years of age from rural areas of Veracruz, México. Materials and methods. We identified eight localities of high priority from the Municipality of Tempoal, Veracruz, for baseline serology...
March 31, 2024: Biomédica: Revista del Instituto Nacional de Salud
#19
JOURNAL ARTICLE
Silvia Fenix-Caballero, Adrián Sanchez-Vegas, Emilio Jesús Alegre Del-Rey, David Epstein, Leticia Garcia-Mochon, Antonio Olry de Labry Lima
INTRODUCTION: Abemaciclib is an oral inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). Data from the clinical trial monarchE (2023) showed improved survival from invasive disease. The aim of the present article was to conduct an economic assessment of adjuvant treatment with abemaciclib in women with luminal, HER2- and node-positive breast cancer. METHODS: A Markov model was constructed with four mutually exclusive health states (disease-free, local recurrence, distal recurrence and death)...
April 22, 2024: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
#20
REVIEW
Kristin N Henning, Rebba D Omer, Janet M de Jesus, Kristen Giombi, Jessi Silverman, Elle Neal, Tanya Agurs-Collins, Alison G M Brown, Charlotte Pratt, Sung Sug Sarah Yoon, Funke Ajenikoko, Erin Iturriaga
Every year, hundreds of thousands of youth across the country enter the juvenile legal system. A significantly disproportionate number of them are youth of color. While youth arrests have declined over the past several decades, racial disparities have increased and persist at every stage of the system. Many youth of color enter the juvenile legal system with a history of trauma and stress that compromises their health and well-being. Arrest, prosecution, and incarceration exacerbate these poor health outcomes...
April 22, 2024: Journal of Racial and Ethnic Health Disparities
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