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JOURNAL ARTICLE
Rafaela Oliveira Pilecco, Lucas Saldanha da Rosa, Andrea Baldi, Renan Vaz Machry, João Paulo Mendes Tribst, Luiz Felipe Valandro, Cornelis Johannes Kleverlaan, Nicola Scotti, Gabriel Kalil Rocha Pereira
The aim of this in vitro study was to evaluate the effect of the combinations of two different intraoral scanners (IOS), two milling machines, and two restorative materials on the marginal/internal fit and fatigue behavior of endocrowns produced by CAD-CAM. Eight groups (n= 10) were considered through the combination of TRIOS 3 (TR) or Primescan (PS) IOS; 4-axes (CR; CEREC MC XL) or 5-axes (PM; PrograMill PM7) milling machines; and lithium disilicate (LD; IPS e.max CAD) or resin composite (RC; Tetric CAD) restorative materials...
April 18, 2024: Journal of the Mechanical Behavior of Biomedical Materials
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JOURNAL ARTICLE
Yuta Ito, Amira Marouf, Yasunori Kogure, Junji Koya, Raphaël Liévin, Julie Bruneau, Mariko Tabata, Yuki Saito, Sumito Shingaki, Mitsuhiro Yuasa, Kentaro Yamaguchi, Koichi Murakami, Robert Weil, Manon Vavasseur, Guillaume P Andrieu, Mehdi Latiri, Layla Veleanu, Michaël Dussiot, Isabelle André, Akshay Joshi, Chantal Lagresle-Peyrou, Aude Magerus, Sammara Chaubard, David Lavergne, Emmanuel Bachy, Erika Brunet, Virginie Fataccioli, Chantal Brouzes, Camille Laurent, Laurence De Leval, Alexandra Traverse-Glehen, Céline Bossard, Marie-Cécile Parrens, Véronique Meignin, Laure Philippe, Julien Rossignol, Felipe Suarez, Jean-Marie Michot, Olivier Tournilhac, Gandhi Damaj, François Lemonnier, Christine Bôle-Feysot, Patrick Nitschké, Bruno Tesson, Cécile Laurent, Thierry Molina, Vahid Asnafi, Yosaku Watatani, Kenichi Chiba, Ai Okada, Yuichi Shiraishi, Sachiko Tsukita, Koji Izutsu, Hiroaki Miyoshi, Koichi Ohshima, Seiji Sakata, Akito Dobashi, Kengo Takeuchi, Masashi Sanada, Philippe Gaulard, Arnaud Jaccard, Seishi Ogawa, Olivier Hermine, Keisuke Kataoka, Lucile Couronné
Extranodal NK/T-cell lymphoma (ENKTCL) is an Epstein-Barr virus (EBV)-related neoplasm with male dominance and a poor prognosis. A better understanding of the genetic alterations and their functional roles in ENKTCL could help improve patient stratification and treatments. Here, we performed comprehensive genetic analysis of 177 ENKTCL cases to delineate the landscape of mutations, copy number alterations (CNAs), and structural variations, identifying 34 driver genes including six previously unappreciated ones, namely HLA-B, HLA-C, ROBO1, CD58, POT1, and MAP2K1...
April 24, 2024: Cancer Research
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JOURNAL ARTICLE
Dixan Pozo-Leyva, Fernando Casanova-Lugo, Felipe López-González, María D Celis-Álvarez, Alvar A Cruz-Tamayo, Jorge R Canúl-Solís, Alfonso J Chay-Canúl
This study evaluated three continuous grazing systems: Brachiaria Brizantha, Clitoria ternatea and naturalized pastures, complemented with commercial concentrate and C. ternatea silage on milk yield, nutrient use and enteric methane (CH4 ) emissions. Nine multiparous cows of local Zebu breeds, with an average weight of 448 ± 87 kg, were used. The chemical composition of the food was determined. Live weight, milk production, and quality were assessed. Furthermore, serum urea, urea nitrogen, creatinine and glucose in blood were monitored, and nitrogen use efficiency were calculated...
April 24, 2024: Tropical Animal Health and Production
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Ghee Rye Lee, Adam E Flanders, Tyler Richards, Felipe Kitamura, Errol Colak, Hui Ming Lin, Robyn L Ball, Jason Talbott, Luciano M Prevedello
No abstract text is available yet for this article.
May 2024: Radiology. Artificial intelligence
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REVIEW
Felipe Muñoz, Malin Fex, Thomas Moritz, Hindrik Mulder, Luis Rodrigo Cataldo
Pancreatic β cells play an essential role in the control of systemic glucose homeostasis as they sense blood glucose levels and respond by secreting insulin. Upon stimulating glucose uptake in insulin-sensitive tissues post-prandially, this anabolic hormone restores blood glucose levels to pre-prandial levels. Maintaining physiological glucose levels thus relies on proper β-cell function. To fulfill this highly specialized nutrient sensor role, β cells have evolved a unique genetic program that shapes its distinct cellular metabolism...
April 24, 2024: Acta Physiologica
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JOURNAL ARTICLE
Madona Tito-Betancur, Renzo Felipe Carranza Esteban, Calixto Tapullima-Mori, Josué Turpo Chaparro, Oscar Mamani-Benito
INTRODUCTION: Financial health is related to the overall health of an individual and their family. The objective of this study was to evaluate the scientific production on financial health in the Scopus database for the 2011-2022 period. METHOD: Scoping review of manuscripts published in journals indexed in the Scopus database between the years 2011 and 2022. The following search terms were used: "Financial obligations", "financial inclusion", "family economy", "financial education", "financial literacy", "financial wellness" and "financial stress", which were entered in the Scopus search engine together with the Boolean operators (AND, OR)...
January 18, 2024: Archivos de Prevención de Riesgos Laborales
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JOURNAL ARTICLE
Luciana Audi Castroneves, Flavia Regina Rotea Mangone, Antonio Marcondes Lerario, Ana Maria da Cunha Mercante, Rafael Loch Batista, Luciana Rodrigues Carvalho Barros, Carla Vaz Ferreira, Evelin Cavalcante Farias, Felipe Augusto Brasileiro Vanderlei, Ana Luiza Maia, Maria Aparecida Nagai, Alexander Augusto Lima Jorge, Ana Oliveira Hoff
CONTEXT: Genetic analysis of sporadic medullary thyroid carcinoma (MTC) has revealed somatic variants in RET , RAS , and occasionally other genes. However, around 20% of patients with sporadic MTC lack a known genetic driver. OBJECTIVE: To uncover potential new somatic or germline drivers, we analyze a distinct cohort of patients with sporadic, very early-onset, and aggressive MTC. METHODS: Germline and somatic DNA exome sequencing was performed in 19 patients, previously tested negative for germline RET variants...
April 6, 2024: Journal of the Endocrine Society
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EDITORIAL
Felipe N Martins, José Lima, Andre Schneider de Oliveira, Paulo Costa, Amy Eguchi
No abstract text is available yet for this article.
2024: Frontiers in Robotics and AI
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JOURNAL ARTICLE
Peter Novodvorský, Lenka Thieme, Ivana Laňková, Miloš Mráz, Zoltán J Taybani, Balázs Bótyik, Péter Stella, Miroslav Vytasil, Felipe Lauand, Mireille Bonnemaire, Martin Haluzík
INTRODUCTION: Multiple daily injection insulin regimen (MDI) represents the most intensive insulin regimen used in the management of people with type 2 diabetes (PwT2D). Its efficacy regarding glycaemic control is counterbalanced by the increased risk of hypoglycaemia, frequently observed tendency to weight gain and necessity for frequent glucose monitoring. Recent introduction of novel antidiabetic medications with pleiotropic effects reaching far beyond the reduction of glycaemia (HbA1c), such as the glucagon-like peptide 1 receptor agonist (GLP-1 RA), has significantly widened the therapeutic options available for management of T2D...
April 24, 2024: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
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JOURNAL ARTICLE
Frank August de Oliveira Toledo, Daniel Oliveira Dos Santos, Izabela Magalhães Arthuso Vasconcelos, Ayisa Rodrigues Oliveira, Juliana Araújo Gomes Cabral, Rômulo Antônio Righi de Toledo, Pedro Hugo Henriques Cunha, Diego Felipe Alves Batista, Fabiola de Oliveira Paes Leme, Marcelo Pires Nogueira de Carvalho, Tatiane Alves da Paixão, Mariana Machado-Neves, Marilia Martins Melo, Renato Lima Santos
Anthropogenic activities are the main sources of soil, air, and water pollution by metals, including cadmium (Cd), lead (Pb), chromium (Cr), the metalloid arsenic (As), magnesium (Mg), zinc (Zn), and copper (Cu). The goal of this study was to assess the presence and concentration of toxic (As, Cd, Pb, and Cr) and essential metals (Mg, Zn, and Cu) in the liver and kidneys from 96 free-ranging rattlesnakes (Crotalus durissus) from Minas Gerais (Brazil). Bioaccumulation of Cd and Pb were significantly higher in males and heavier rattlesnakes (those with body weight above the average of the study population)...
April 23, 2024: Environmental Science and Pollution Research International
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JOURNAL ARTICLE
Vítor Rodrigues Marin, Caio Felipe Cavicchia Zamuner, Giovane Böerner Hypolito, Juliano Henrique Ferrarezi, Natália Alleoni, Mario Nicolas Caccalano, Henrique Ferreira, Daiane Cristina Sass
Citrus canker is a disease caused by the Gram-negative bacterium Xanthomonas citri subp. citri (X. citri), which affects all commercially important varieties of citrus and can lead to significant losses. Fruit sanitization with products such as chlorine-based ones can reduce the spread of the disease. While effective, their usage raises concerns about safety of the workers. This work proposes essential oils (EOs) as viable alternatives for fruit sanitization. EOs from Cymbopogon species were evaluated as to their antibacterial activity, their effect on the bacterial membrane, and their ability to sanitize citrus fruit...
April 23, 2024: Letters in Applied Microbiology
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JOURNAL ARTICLE
Kevin Pacheco-Barrios, Paulo E P Teixeira, Daniela Martinez-Magallanes, Moacir Silva Neto, Elly Angelica Pichardo, Lucas Camargo, Daniel Lima, Alejandra Cardenas-Rojas, Felipe Fregni
BACKGROUND: The different clinical presentations of fibromyalgia (FMS) may play independent roles in the unclear etiology of cognitive impairments and depressive symptoms seen in this population. Understanding how these clinical presentations are associated with FMS's clinical and neurophysiological aspects is important when developing effective treatments. AIM: To explore the relationship between memory complaints and depressive symptoms, and the different clinical and neurophysiological characteristics of FMS...
April 23, 2024: Pain Medicine
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JOURNAL ARTICLE
Lais Ceschini Machado, Filipe Zimmer Dezordi, Gustavo Barbosa de Lima, Raul Emídio de Lima, Lilian Caroliny Amorim Silva, Leandro de Mattos Pereira, Alexandre Freitas da Silva, Antonio Marinho da Silva Neto, André Luiz Sá de Oliveira, Anderson da Costa Armstrong, Rômulo Pessoa-E-Silva, Rodrigo Moraes Loyo, Barbara de Oliveira Silva, Anderson Rodrigues de Almeida, Maira Galdino da Rocha Pitta, Francisco de Assis da Silva Santos, Marilda Mendonça Siqueira, Paola Cristina Resende, Edson Delatorre, Felipe Gomes Naveca, Fabio Miyajima, Tiago Gräf, Rodrigo Feliciano do Carmo, Michelly Cristiny Pereira, Tulio de Lima Campos, Matheus Filgueira Bezerra, Marcelo Henrique Santos Paiva, Gabriel da Luz Wallau
SARS-CoV-2 virus emerged as a new threat to humans and spread around the world, leaving a large death toll. As of January 2023, Brazil is among the countries with the highest number of registered deaths. Nonpharmacological and pharmacological interventions have been heterogeneously implemented in the country, which, associated with large socioeconomic differences between the country regions, has led to distinct virus spread dynamics. Here, we investigate the spatiotemporal dispersion of SARS-CoV-2 lineages in the Pernambuco state (Northeast Brazil) throughout the distinct epidemiological scenarios that unfolded in the first 2 years of the pandemic...
April 23, 2024: Microbiology Spectrum
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REVIEW
Jorge A Barrero, Felipe Duarte-Zambrano, Ismena Mockus
Background: The imminent increase in overweight and obesity prevalence constitutes a pervasive concern for the adult and pediatric Colombian population. Nonetheless, the unequal distribution across distinct social groups limits the implementation of public health policies targeting these escalating rates. Aim: This study aimed to compile existing evidence regarding the prevalence of overweight and obesity in relation to the socioeconomic status (SES) of the Colombian population. Methods: A scoping review was conducted according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews parameters in MEDLINE (PubMed), EMBASE, and LILACS databases for inclusion of investigations published up to January 2024...
April 23, 2024: Nutrition and Health
#15
Homero Loza, Gabriela Carrión, Alexis Haro, Felipe Loza
Hepatic rupture is a rare complication of severe preeclampsia. A high index of suspicion is required in the presence of abdominal pain accompanied by hemodynamic decompensation in a pregnant woman. Hepatic rupture constitutes a medical emergency that demands immediate intervention, often with the support of other medical disciplines, in a highly specialized hospital setting. Unruptured hepatic hematomas can be managed conservatively. Immediate delivery and surgical repair of the liver are necessary for maternal survival...
March 2024: Curēus
#16
JOURNAL ARTICLE
Jaiberth Antonio Cardona-Arias, Mauricio Vidales-Silva, Alexandra Ocampo-Ramírez, Luis Felipe Higuita-Gutiérrez, Juan Carlos Cataño-Correa
INTRODUCTION: In Colombia, HIV and gestational syphilis are notifiable events; however, they are poorly investigated infections in men who have sex with men (MSM). OBJECTIVE: To determine the prevalence of HIV, Treponema pallidum , and their co-infection in MSM treated at a Health Services Provider Institution (HSPI) specialized in infectious diseases from Medellín. METHODS: Cross-sectional study with 3454 MSM. Prevalence was determined with its 95% confidence interval; associated factors were identified using Fisher's Exact test, Pearson's Chi-square, and trend Chi-square...
2024: HIV/AIDS: Research and Palliative Care
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JOURNAL ARTICLE
Qingxian Chen, Manesh Gopaldas, Felipe Castillo, Emily Leckman-Westin, Edward V Nunes, Frances R Levin, Molly T Finnerty
OBJECTIVE: The authors examined the prevalence and correlates of co-occurring opioid use disorder and opioid overdose among individuals receiving psychiatric services. METHODS: This was a cross-sectional study of adults with continuous enrollment in New York State Medicaid who received at least one psychiatric service in 2020 (N=523,885). Logistic regression models were used to examine the correlates of both opioid use disorder and overdose. RESULTS: In the study sample, the prevalence rate of opioid use disorder was 8...
April 23, 2024: Psychiatric Services: a Journal of the American Psychiatric Association
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REVIEW
S Peters, S Loi, F André, S Chandarlapaty, E Felip, S P Finn, P A Jänne, K M Kerr, E Munzone, A Passaro, M Pérol, E F Smit, C Swanton, G Viale, R A Stahel
Following the approval of the first antibody-drug conjugates (ADCs) in the early 2000s, development has increased dramatically, with 14 ADCs now approved and >100 in clinical development. In lung cancer, trastuzumab deruxtecan (T-DXd) is approved in human epidermal growth factor receptor 2 (HER2)-mutated, unresectable or metastatic non-small cell lung cancer, with ADCs targeting HER3 (patritumab deruxtecan), trophoblast cell-surface antigen 2 (datopotamab deruxtecan and sacituzumab govitecan [SG]) and mesenchymal-epithelial transition factor (telisotuzumab vedotin) in late-stage clinical development...
April 20, 2024: Annals of Oncology: Official Journal of the European Society for Medical Oncology
#19
JOURNAL ARTICLE
Luiz Gustavo T Fabricio Dos Santos, Isabella Dos Santos Alves, Náthali Fernanda Feliciano, Africa Alejandra Ortuño Torres, Luis Felipe Castelli Correia de Campos, Maria Luiza Tanure Alves
The journey of Brazilian female Paralympians transcends mere statistical increases in women's participation. Behind the modest athlete growth lies the reality of women who are doubly marginalized by the intersection of gender and disability in an arena tailored for able-bodied men. Our study aimed to catalyze critical discourses surrounding the historical trajectory of Paralympic women's sports. Through a comprehensive documentary analysis based on the Brazilian Paralympic Committee's official documents from 1976 to 2021, we sought to shed light on this complex scenario...
April 22, 2024: Adapted Physical Activity Quarterly: APAQ
#20
JOURNAL ARTICLE
Felipe Agudelo-Hernández, Ana Giraldo Alvarez, Rodrigo Rojas-Andrade
Based on the need to implement strategies to reduce recovery gaps in mental health with the community as axes of recovery, the objective of the present study was to assess the impact on psychosocial disability and care continuity in individuals with suicidal behavior, of the clinical and community components of the Mental Health Gap Action Program (mhGAP), versus exclusive psychiatric care. For this, a controlled community trial carried out in 2023 was conducted, comprising intervention groups: Support Group (SG), mhGAP Group (mhGAPG) and a Control Group (CG)...
April 22, 2024: Psychological Reports
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