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https://www.readbyqxmd.com/read/28350480/lung-cancer-in-never-smoking-women-a-sub-analysis-of-the-spanish-female-specific-database-world07
#1
Nuria Viñolas, Pilar Garrido, Dolores Isla, Mariano Provencio, Margarita Majem, Angel Artal, Enric Carcereny, Rosario Garcia Campelo, Pilar Lianes, Ramon De La Peñas, Enriqueta Felip
The WORLD07 study characterizes lung cancer in Spanish women. This analysis investigated lung cancer features in never-smoking women. Of 2072 women recruited, 2035 were analyzed. Patient characteristics and demographics were similar for current/former smokers and never smokers. Among never smokers, 38.3% were exposed to passive smoking. Non-small-cell lung cancer was the most common type (78.8% of current/former smokers and 96.1% of never smokers) and adenocarcinoma the most common histology (69.1% and 83.4% respectively)...
March 28, 2017: Cancer Investigation
https://www.readbyqxmd.com/read/28350447/self-functionalization-behind-a-solution-processed-niox-film-used-as-hole-transporting-layer-for-efficient-perovskite-solar-cells
#2
John Ciro, Daniel Ramírez, Mario Alejandro Mejía Escobar, Juan Felipe Montoya, Santiago Mesa, Rafael Betancur, Franklin Jaramillo
Fabrication of solution-processed perovskite solar cells (PSCs) requires the deposition of high quality films from precursor inks. Frequently, buffer layers of PSCs are formed from dispersions of metal oxide nanoparticles (NPs). Therefore, the development of trustable methods for the preparation of stable colloidal NPs dispersions is crucial. In this work, a novel approach to form very compact semiconducting buffer layers with suitable optoelectronic properties is presented through a self-functionalization process of the nanocrystalline particles by their own amorphous phase and without adding any other inorganic or organic functionalization component or surfactant...
March 28, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28346259/igg4-related-ophthalmic-disease-presenting-as-choroidal-and-orbital-lesions
#3
William S Gange, Stephen M Holland, Felipe De Alba
PURPOSE: To report a case of IgG4-related ophthalmic disease (IgG4-ROD) which presented as choroidal and orbital lesions. METHODS: Case report. RESULTS: A 64-year-old man presented with left eye photopsias and a history of IgG4-related perirenal fibrosis. Fundoscopic examination showed multiple bilateral yellow choroidal lesions, and optical coherence tomography showed multiple choroidal lesions. Magnetic resonance imaging of the orbits showed an enhancing lesion present circumferential to the optic nerve, but greater medially, abutting the posterior surface of the left globe...
March 24, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28345339/synthesis-of-positional-isomeric-phenylphenalenones
#4
Felipe Ospina, Adrian Ramirez, Marisol Cano, William Hidalgo, Bernd Schneider, Felipe Otálvaro
A series of isomeric phenylphenalenones in which the phenyl ring is located at all possible peripheral positions of the phenalenone nuclei was synthesized. The structural characteristics of the series, in which topological variation is permitted with minimal electronic disturbance, could, in principle, allow for easy pharmacophore recognition when the compounds are aligned in steroidomimetic conformations.
March 27, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28345265/cytokine-and-antioxidant-gene-profiles-from-peripheral-blood-mononuclear-cells-of-pelibuey-lambs-after-haemonchus-contortus-infection
#5
Zaira Estrada-Reyes, Ma Eugenia López-Arellano, Felipe Torres-Acosta, Alberto López-Reyes, Alfredo Lagunas-Martínez, Pedro Mendoza-de-Gives, Roberto González-Garduño, Sara Olazarán-Jenkins, David Reyes-Guerrero, Gabriel Ramírez-Vargas
The expression profiles of cytokines and anti-oxidant genes were determined from an experimental infection with H. contortus in Pelibuey lambs. The infection was followed for 34 days (d) to determine the number of eggs per gram (epg) and the packed cell volume (PCV). Differential white cell counts and expression profile estimations of IL2, IL4, IL5, IL6, IL8, IL10, IL13, FCεR1A, GPX and SOD1 were determined at 0 h, 4 h, 2 d and 14 d post-infection (PI) in infected and control groups. Comparison of the fold-change between 0 and 4 h, 4 h and 2 d, and 2 and 14 d periods was performed...
March 27, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28344986/erratum-to-pharmacological-treatments-of-presbyopia-a-review-of-modern-perspectives
#6
Antonio Renna, Jorge L Alió, Luis Felipe Vejarano
[This corrects the article DOI: 10.1186/s40662-017-0068-8.].
2017: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/28344378/the-long-and-the-short-of-it-a-global-analysis-of-hawkmoth-pollination-niches-and-interaction-networks
#7
Steven D Johnson, Marcela Moré, Felipe W Amorim, William A Haber, Gordon W Frankie, Dara A Stanley, Andrea A Coccuci, Robert A Raguso
1. Proboscis length has been proposed as a key dimension of plant pollination niches, but this niche space has not previously been explored at regional and global scales for any pollination system. Hawkmoths are ideal organisms for exploring pollinator niches as they are important pollinators in most of the biodiverse regions of the earth and vary greatly in proboscis length, with some species having the longest proboscides of all insects. 2. Using datasets for nine biogeographical regions spanning the Old and New World, we ask whether it is possible to identify distinct hawkmoth pollination niches based on the frequency distribution of proboscis length, and whether these niches are reflected in the depths of flowers that are pollinated by hawkmoths...
January 2017: Functional Ecology
https://www.readbyqxmd.com/read/28343624/salivary-%C3%AE-2-microglobulin-positively-correlates-with-esspri-in-patients-with-primary-sj%C3%A3-gren-s-syndrome
#8
Felipe Garza-García, Guillermo Delgado-García, Mario Garza-Elizondo, Luis Ángel Ceceñas-Falcón, Dionicio Galarza-Delgado, Janett Riega-Torres
No abstract text is available yet for this article.
March 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28343257/leaf-ontogeny-of-schinus-molle-l-plants-under-cadmium-contamination-the-meristematic-origin-of-leaf-structural-changes
#9
Marcio Paulo Pereira, Felipe Fogaroli Corrêa, Evaristo Mauro de Castro, Jean Paulo Vitor de Oliveira, Fabricio José Pereira
Previous works show the development of thicker leaves on tolerant plants growing under cadmium (Cd(2+)) contamination. The aim of this study was to evaluate the Cd(2+) effects on the leaf meristems of the tolerant species Schinus molle. Plants were grown in nutrient solution containing 0, 10, and 50 μM of Cd(2+). Anatomical analysis was performed on leaf primordia sampled at regular time intervals. Under the lowest Cd(2+) level (10 μM), increased ground meristem thickness, diameter of the cells, cell elongation rate, and leaf dry mass were found...
March 25, 2017: Protoplasma
https://www.readbyqxmd.com/read/28342611/short-communication-identification-of-corynebacterium-bovis-by-matrix-assisted-laser-desorption-ionization-mass-spectrometry
#10
Helio Langoni, Carolina Polo Camargo da Silva, Marcella Zampoli Troncarelli, Alessandra Tata, Katia Roberta Anacleto Belaz, Marcos Nogueira Eberlin, Samea Fernandes Joaquim, Felipe Freitas Guimarães, Renata Bonini Pardo, Eduardo Nardini Gomes
Corynebacterium bovis is a mastitis-causing microorganism responsible for economic losses related to decrease in milk production. The aim of the study was identify Corynebacterium spp. strains recovered from milk samples of subclinical mastitis by using matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). Samples were collected during a 10-mo mastitis-monitoring program in a high-production dairy farm. In this study, 80 strains were analyzed; from these 54 (67.5%) were identified at species level as Corynebacterium bovis, 24 (31...
March 22, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28342126/learning-curve-takes-65-repetitions-of-totally-extraperitoneal-laparoscopy-on-inguinal-hernias-for-reduction-of-operating-time-and-complications
#11
Fábio Yuji Suguita, Felipe Futema Essu, Lucas Torres Oliveira, Leandro Ryuchi Iuamoto, Juliana Mika Kato, Matheus Beloni Torsani, André Silva Franco, Alberto Meyer, Wellington Andraus
BACKGROUND: Inguinal hernia repair is one of the most frequently conducted surgical procedures worldwide. Totally extraperitoneal (TEP) hernioplasty has shown many advantages over traditional open surgery. However, because of increased surgical complexity, it requires more practice to achieve optimal results. OBJECTIVES: The aim of this study is to evaluate the learning curve for TEP hernioplasty, analysing parameters related to the mean operating time. The secondary objective is to assess the complications and early discharge rates related to this procedure...
March 24, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28341965/reliability-of-a-laryngo-pharyngeal-esthesiometer-and-a-method-for-measuring-laryngo-pharyngeal-mechano-sensitivity-in-a-prospectively-recruited-cohort-of-patients
#12
Luis F Giraldo-Cadavid, Javier Burguete, Felipe Rueda, Ana M Galvis, Natalia Castaneda, Luis M Agudelo-Otalora, William D Moscoso, Nelson Paez, Secundino Fernandez
There are not reliable methods for measuring laryngo-pharyngeal mechano-sensitivity (LPMS). We aimed to determine the reliability of a new method for measuring LPMS using a new laryngo-pharyngeal esthesiometer (LPEER) in a prospective cohort of dysphagic stroke and non-dysphagic patients. The patients underwent clinical and endoscopic evaluations of swallowing (FESSST). The LPMS assessments consisted of measurements by an expert and a novel rater of the laryngeal-adductor reflex threshold (LART), cough reflex threshold (CRT) and gag reflex threshold (GRT) using the LPEER...
March 24, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28341740/nanomolar-nitric-oxide-concentrations-quickly-and-reversibly-modulate-astrocytic-energy-metabolism
#13
Alejandro San Martín, Robinson Arce-Molina, Alex Galaz, Gustavo Pérez-Guerra, L Felipe Barros
Nitric oxide (NO) is an intercellular messenger involved in multiple bodily functions. Prolonged NO exposure irreversibly inhibits respiration by covalent modification of mitochondrial cytochrome oxidase, a phenomenon of pathological relevance. However, the speed and potency of NO's metabolic effects at physiological concentrations are incompletely characterized. To this end, we set out to investigate the metabolic effects of NO in cultured astrocytes from mice by taking advantage of the high spatiotemporal resolution afforded by genetically-encoded Foerster resonance energy transfer (FRET) nanosensors...
March 24, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28340618/are-cells-from-a-snowman-realistic-cryopreserved-tissues-as-a-source-for-single-cell-rna-sequencing-experiments
#14
Felipe A Vieira Braga, Sarah A Teichmann, Michael J T Stubbington
A recently published study in Genome Biology shows that cells isolated from cryopreserved tissues are a reliable source of genetic material for single-cell RNA-sequencing experiments.Please see related Method article: http://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1171-9.
March 24, 2017: Genome Biology
https://www.readbyqxmd.com/read/28340281/high-ten-year-remission-rates-following-rituximab-fludarabine-mitoxantrone-and-dexamethasone-r-fnd-with-interferon-maintenance-in-indolent-lymphoma-results-of-a-randomized-study
#15
Loretta J Nastoupil, Peter McLaughlin, Lei Feng, Sattva S Neelapu, Felipe Samaniego, Fredrick B Hagemeister, Ana Ayala, Jorge E Romaguera, Andre H Goy, Eleanor Neal, Michael Wang, Luis Fayad, Michelle A Fanale, Yasuhiro Oki, Jason R Westin, Maria A Rodriguez, Fernando Cabanillas, Nathan H Fowler
We report a single-centre, randomized study evaluating the efficacy and safety of concurrent fludarabine, mitoxantrone, dexamethasone (FND) and rituximab versus sequential FND followed by rituximab in 158 patients with advanced stage, previously untreated indolent lymphoma, enrolled between 1997 and 2002. Patients were randomized to 6-8 cycles of FND followed by 6 monthly doses of rituximab or 6 doses of rituximab given concurrently with FND. All patients who achieved at least a partial response received 12 months of interferon (IFN) maintenance...
March 24, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28338303/what-is-the-quickest-scoring-system-to-predict-percutaneous-nephrolithotomy-outcomes-a-comparative-study-among-s-t-o-n-e-score-guy-s-stone-score-and-croes-nomogram
#16
Fabio C Vicentini, Felipe R Serzedello, Kay Thomas, Giovanni S Marchini, Fabio C M Torricelli, Miguel Srougi, Eduardo Mazzucchi
OBJECTIVE: To compare the application time and the capacity of the nomograms to predict the success of Guy's Stone Score (GSS), S.T.O.N.E. Nephrolithometry (STONE) and Clinical Research Office of the Endourological Society nephrolithometric nomogram (CROES) of percutaneous nephrolithotomy (PCNL), evaluating the most efficient one for clinical use. MATERIALS AND METHODS: We studied 48 patients who underwent PCNL by the same surgeon between 2010 and 2011. We calculated GSS, STONE and CROES based on preoperative non-contrast computed tomography (CT) images and clinical data...
March 24, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28337795/current-update-on-the-diagnosis-and-management-of-head-and-neck-hard-tissue-sarcomas
#17
REVIEW
Ben Tudor-Green, Felipe Paiva Fonseca, Ricardo Gomez, Peter A Brennan
Head and neck hard tissue sarcomas form a rare group of mesenchymal derived tumours that comprise less than 1% of all head and neck neoplasms. Hard tissue sarcomas account for 20% of head and neck sarcomas and they form a heterogeneous group with a diverse origin. Unlike head and neck soft tissue sarcomas, they have lower recurrence and mortality rates. In this article, we review the current management of head and neck hard tissue sarcomas. This article is protected by copyright. All rights reserved.
March 24, 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28337705/the-effects-of-polyunsaturated-fatty-acids-and-antioxidant-vitamins-on-atrial-oxidative-stress-nitrotyrosine-residues-and-connexins-following-extracorporeal-circulation-in-patients-undergoing-cardiac-surgery
#18
Felipe Petersen, Ramón Rodrigo, Manfred Richter, Sawa Kostin
Cardiac surgery with extracorporeal circulation is characterized by different degrees of myocardial ischemia/reperfusion, which is often associated with postoperative atrial fibrillation (POAF). We have previously shown that a novel preventive therapy based on the reinforcement of the antioxidant system using omega-3 fatty acids plus antioxidant vitamin supplementation applied to patients undergoing cardiac surgery reduces POAF occurrence. We hypothesized that oxidative stress and nitrosative stress are involved in the development of an arrhythmogenic substrate by their effect on connexins (Cx40, Cx43 and Cx45) abundance and distribution pattern...
March 23, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28337070/genomic-methods-and-microbiological-technologies-for-profiling-novel-and-extreme-environments-for-the-extreme-microbiome-project-xmp
#19
Scott Tighe, Ebrahim Afshinnekoo, Tara M Rock, Ken McGrath, Noah Alexander, Alexa McIntyre, Sofia Ahsanuddin, Daniela Bezdan, Stefan J Green, Samantha Joye, Sarah Stewart Johnson, Don A Baldwin, Nathan Bivens, Nadim Ajami, Joseph R Carmical, Ian Charold Herriott, Rita Colwell, Mohamed Donia, Jonathan Foox, Nick Greenfield, Tim Hunter, Jessica Hoffman, Joshua Hyman, Ellen Jorgensen, Diana Krawczyk, Jodie Lee, Shawn Levy, Natàlia Garcia-Reyero, Matthew Settles, Kelley Thomas, Felipe Gómez, Lynn Schriml, Nikos Kyrpides, Elena Zaikova, Jon Penterman, Christopher E Mason
The Extreme Microbiome Project (XMP) is a project launched by the Association of Biomolecular Resource Facilities Metagenomics Research Group (ABRF MGRG) that focuses on whole genome shotgun sequencing of extreme and unique environments using a wide variety of biomolecular techniques. The goals are multifaceted, including development and refinement of new techniques for the following: 1) the detection and characterization of novel microbes, 2) the evaluation of nucleic acid techniques for extremophilic samples, and 3) the identification and implementation of the appropriate bioinformatics pipelines...
March 10, 2017: Journal of Biomolecular Techniques: JBT
https://www.readbyqxmd.com/read/28336451/effect-of-soybean-phosphatidylcholine-on-lipid-profile-of-bovine-oocytes-matured-in-vitro
#20
Caroline P Pitangui-Molina, Alessandra A Vireque, Alessandra Tata, Katia Roberta A Belaz, Vanessa G Santos, Christina R Ferreira, Marcos N Eberlin, Marcos Felipe S Sá, Rui A Ferriani, Ana Carolina J S Rosa-E-Silva
The phospholipid (PL) composition of embryo and oocyte membranes affects thermal phase behavior and several physicochemical properties such as fluidity and permeability. The characterization of PL profiles and the development of suitable in vitro maturation (IVM) protocols, that are able to modify membrane's composition, may result in significant improvements in oocyte developmental potential and cryotolerance. Using soybean phosphatidylcholine (PC) as a model supplement, we evaluated the effect of PL supplementation during IVM on bovine cumulus-oocyte-complex (COC)...
March 20, 2017: Chemistry and Physics of Lipids
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