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https://www.readbyqxmd.com/read/28433877/affordances-in-the-home-environment-for-motor-development-validity-and-reliability-for-the-use-in-daycare-setting
#1
Alessandra Bombarda Müller, Nadia Cristina Valentini, Paulo Felipe Ribeiro Bandeira
The range of stimuli provided by physical space, toys and care practices contributes to the motor, cognitive and social development of children. However, assessing the quality of child education environments is a challenge, and can be considered a health promotion initiative. This study investigated the validity of the criterion, content, construct and reliability of the Affordances in the Home Environment for Motor Development - Infant Scale (AHEMD-IS), version 3-18 months, for the use in daycare settings...
April 20, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28433637/inhibition-of-pro-inflammatory-enzymes-by-medicinal-plants-from-the-argentinean-highlands-puna
#2
Romina Torres-Carro, María Inés Isla, Samanta Thomas-Valdes, Felipe Jiménez-Aspee, Guillermo Schmeda-Hirschmann, María Rosa Alberto
ETHNOPHARMACOLOGICAL RELEVANCE: Human groups in the Argentinean Andes highlands (Puna) selected native plants as anti-inflammatory agents. The indications of use are mainly to relieve pain, in infusions, ethanolic extracts or plasters. AIM OF THE STUDY: The objective of the study was to assess the effect of hydroalcoholic extracts from native highland plants as anti-inflammatory according to the traditional indications of use. The chemical profile of the three most active species was analyzed by HPLC-ESI-MS to get in insight into the constituents and the effects observed, according to the ethnopharmacological information...
April 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28433520/corrigendum-to-therapeutic-effect-of-ursolic-acid-in-experimental-visceral-leishmaniasis-int-j-parasitol-drugs-drug-resist-7-2017-1-11
#3
Jessica A Jesus, Thais N Fragoso, Eduardo S Yamamoto, Marcia D Laurenti, Marcelo S Silva, Aurea F Ferreira, João Henrique G Lago, Gabriela Santos-Gomes, Luiz Felipe D Passero
No abstract text is available yet for this article.
April 4, 2017: International Journal for Parasitology, Drugs and Drug Resistance
https://www.readbyqxmd.com/read/28432942/insights-into-the-diversity-of-nod-like-receptors-identification-and-expression-analysis-of-nlrc3-nlrc5-and-nlrx1-in-rainbow-trout
#4
Claudio A Álvarez, Felipe Ramírez-Cepeda, Paula Santana, Elisa Torres, Jimena Cortés, Fanny Guzmán, Paulina Schmitt, Luis Mercado
Nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) are efficient soluble intracellular sensors that activate defense mechanisms against pathogens. In teleost fish, the involvement of NLRs in the immune response is not well understood. However, recent work has evidenced the expression of different NLRs in response to some pathogen associated molecular patterns (PAMPs). In the present work, the cDNA sequence encoding three new NOD-like receptors were identified in Oncorhynchus mykiss, namely OmNLRC3, OmNLRC5 and OmNLRX1...
April 19, 2017: Molecular Immunology
https://www.readbyqxmd.com/read/28432565/parapharyngodon-hugoi-n-sp-a-new-nematode-oxyuroidea-pharyngodonidae-of-the-tree-frog-trachycephalus-typhonius-linnaeus-from-the-brazilian-pantanal-including-a-key-to-the-congeners-from-amphibians-of-the-american-continent
#5
Felipe B Pereira, Karla M Campião, José L Luque, Luiz E R Tavares
A new nematode Parapharyngodon hugoi n. sp. (Oxyuroidea: Pharyngodonidae) is described parasitising the large intestine of the tree frog Trachycephalus typhonius (Linnaeus) (Anura: Hylidae) from the wetlands of Pantanal, State of Mato Grosso do Sul, Brazil. The new species exhibits a unique structure of the posterior cloacal lip in males, which is supported by a rigid V-shaped structure. Parapharyngodon hylidae parasitic in hylid frogs, including T. typhonius, from Mexico, is the most similar congener to P...
April 21, 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28431817/pneumococcal-carriage-among-children-after-four-years-of-routine-10-valent-pneumococcal-conjugate-vaccine-use-in-brazil-the-emergence-of-multidrug-resistant-serotype-6c
#6
Felipe P G Neves, Nayara T Cardoso, Robert E Snyder, Mariel A Marlow, Claudete A A Cardoso, Lúcia M Teixeira, Lee W Riley
BACKGROUND: In 2010, the 10-valent pneumococcal conjugate vaccine (PCV10) was introduced free of charge in Brazil as part of the public immunization program. Here we investigated the carriage prevalence, colonization risk factors, capsular types, and antimicrobial resistance among pneumococcal isolates obtained from children in Brazil four years after routine PCV10 use. METHODS: Between September and December 2014, we conducted a cross-sectional study among children<6years old who attended one public and two private clinics in Niterói, RJ, Brazil to evaluate pneumococcal nasopharyngeal carriage...
April 18, 2017: Vaccine
https://www.readbyqxmd.com/read/28431491/fluoride-varnishes-containing-sodium-trimetaphosphate-reduce-enamel-demineralization-in-vitro
#7
Michele M Manarelli, Alberto C B Delbem, Liliana Carolina Báez-Quintero, Felipe Ricardo N de Moraes, Robson F Cunha, Juliano P Pessan
OBJECTIVE: This study evaluated the effects of fluoride varnishes containing sodium trimetaphosphate (TMP) on bovine enamel demineralization in vitro. MATERIAL AND METHODS: Enamel bovine discs were randomly assigned into six groups (n = 20/group): placebo, 2.5% NaF, 2.5% NaF/5% TMP, 5% NaF, 5% NaF/5% TMP, and a commercial formulation (Duraphat, 5% NaF). Varnishes were applied on all enamel discs and kept for 6 h. Loosely and firmly bound fluoride formed on/in enamel after treatment were analyzed in 10 discs from each group...
April 21, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28431490/new-challenges-in-therapeutic-vaccines-against-hiv-infection
#8
Lorna Leal, Constanza Lucero, Josep M Gatell, Teresa Gallart, Montserrat Plana, Felipe García
There is a growing interest in developing curative strategies for HIV infection. Therapeutic vaccines are one of the most promising approaches. We will review the current knowledge and the new challenges in this research field. Areas covered: PubMed and ClinicalTrial.gov databases were searched to review the progress and prospects for clinical development of immunotherapies aimed to cure HIV infection. Dendritic cells (DC)-based vaccines have yielded the best results in the field. However, major immune-virologic barriers may hamper current vaccine strategies...
April 21, 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28431294/exploring-the-experience-of-episodic-past-future-and-counterfactual-thinking-in-younger-and-older-adults-a-study-of-a-colombian-sample
#9
Felipe De Brigard, Diana Carolina Rodriguez, Patricia Montañés
Although extant evidence suggests that many neural and cognitive mechanisms underlying episodic past, future, and counterfactual thinking overlap, recent results have uncovered differences among these three processes. However, the extent to which there may be age-related differences in the phenomenological characteristics associated with episodic past, future and counterfactual thinking remains unclear. This study used adapted versions of the Memory Characteristics Questionnaire and the Autobiographical Interview in younger and older adults to investigate the subjective experience of episodic past, future and counterfactual thinking...
April 17, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28430532/overcoming-discourse-linking-difficulties-in-aphasia-the-case-of-clitic-pronouns
#10
Silvia Martínez-Ferreiro, Andrés Felipe Reyes, Roelien Bastiaanse
The present study aims to contribute to the ongoing discussion about the impact of discourse-linking deficits on the performance of individuals with aphasia by providing new data from a set of rarely investigated constructions: sentences in which a clitic pronoun coexists alongside with the full DP it agrees with. To do so, we use data of individuals with non-fluent aphasias who need to overcome the difficulties in direct object (accusative) clitic production. This results in overproduction of non-target clitic right dislocations (RDs) and clitic doubling (CD)...
April 21, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28430081/prevalence-and-factors-associated-with-criminal-behavior-among-illicit-drug-users-a-cross-sectional-study
#11
Rafael Alves Guimarães, Natália Silva Mesquita, Renata Silva Lopes, Roselma Lucchese, Rodrigo Lopes de Felipe, Ivânia Vera, Inaina Lara Fernandes, Paulo Alexandre de Castro, Luiz Henrique Batista Monteiro, Graciele Cristina Silva
BACKGROUND: Studies indicate high rates of criminal behavior, violent activities, and legal problems among illicit drug users (IDU) in Brazil. The aim of this study was to estimate the prevalence and factors associated with criminal behavior among IDU undergoing treatment for chemical dependency in Central Brazil. METHODS: Cross-sectional study carried out with IDU undergoing treatment for chemical dependence. Data were collected by means of face-to-face interviews and analyzed using logistic regression...
April 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28429898/subclassification-of-the-molecular-types-of-breast-cancer-based-on-the-expression-of-immunohistochemical-markers-and-evolution
#12
Aldo Reigosa, David Hardisson, Francisco Sanzi, Eduardo Caleiras, Felipe Saldivia, Angel Fernández
Breast carcinomas have been classified from the molecular point of view into four major groups (Luminal A, Luminal B, HER2 and triple negative). However, these groups are not homogeneous and there is a need to establish subcategories that can be identified by immunohistochemistry (IHC), to better predict prognosis and carry out treatments that are more effective. This study was conducted in 354 patients diagnosed with invasive ductal breast carci- noma. The expression of 22 molecules was analyzed by tissue matrices and the results obtained were compared with molecular classes defined by IHC, according to the expression of estrogen receptor (ER), progesterone receptor (PR) and HER2, and the overall survival...
June 2016: Investigación Clínica
https://www.readbyqxmd.com/read/28429400/the-circadian-clock-component-lhy-tells-a-plant-when-to-respond-photosynthetically-to-light-in-nature
#13
Youngsung Joo, Variluska Fragoso, Felipe Yon, Ian T Baldwin, Sang-Gyu Kim
The circadian clock is known to increase plant growth and fitness, and thought to prepare plants for photosynthesis at dawn and dusk; whether this happens in nature was unknown. We transformed the native tobacco, Nicotiana attenuata to silence two core clock components, NaLHY (irLHY) and NaTOC1 (irTOC1). We characterized growth and light-and dark-adapted photosynthetic rates (Ac ) throughout a 24 h day in empty vector-transformed (EV), irLHY, and irTOC1 plants in the field, and in NaPhyA-and NaPhyB1-silenced plants in the glasshouse...
April 21, 2017: Journal of Integrative Plant Biology
https://www.readbyqxmd.com/read/28428654/computed-tomography-guided-percutaneous-gastrostomy-initial-experience-at-a-cancer-center
#14
Chiang Jeng Tyng, Erich Frank Vater Santos, Luiz Felipe Alves Guerra, Almir Galvão Vieira Bitencourt, Paula Nicole Vieira Pinto Barbosa, Rubens Chojniak
Gastrostomy is indicated for patients with conditions that do not allow adequate oral nutrition. To reduce the morbidity and costs associated with the procedure, there is a trend toward the use of percutaneous gastrostomy, guided by endoscopy, fluoroscopy, or, most recently, computed tomography. The purpose of this paper was to review the computed tomography-guided gastrostomy procedure, as well as the indications for its use and the potential complications.
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28427542/recurrent-respiratory-papillomatosis-a-state-of-the-art-review
#15
REVIEW
Helena Ribeiro Fortes, Felipe Mussi von Ranke, Dante Luiz Escuissato, Cesar Augusto Araujo Neto, Gláucia Zanetti, Bruno Hochhegger, Carolina Althoff Souza, Edson Marchiori
Recurrent respiratory papillomatosis (RRP) is a benign disease of the upper aero-digestive tract caused by human papillomavirus (HPV) infection, which affects children and young adults. The aim of this review is to describe the main etiological, epidemiological, clinical, diagnostic, and treatment aspects of RRP. Most infections in children occur at birth, during passage through the birth canals of contaminated mothers. In adults, HPV is transmitted sexually. Papillomas usually appear as exophytic nodules, primarily in the larynx, but occasionally involving the nasopharynx, tracheobronchial tree, and pulmonary parenchyma...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28427013/the-accelerated-path-of-ceritinib-translating-pre-clinical-development-into-clinical-efficacy
#16
REVIEW
Tony S K Mok, Lucio Crino, Enriqueta Felip, Ravi Salgia, Tommaso De Pas, Daniel S W Tan, Laura Q M Chow
The discovery of anaplastic lymphoma kinase (ALK)-rearranged non-small-cell lung cancer (NSCLC) in 2007 led to the development and subsequent approval of the ALK inhibitor crizotinib in 2011. However, despite its clinical efficacy, resistance to crizotinib invariably develops. There is now a next generation of ALK inhibitors, including two that have been approved-ceritinib and alectinib-and others that are in development-brigatinib, lorlatinib and X-396. Ceritinib and the other next-generation ALK inhibitors are more potent than crizotinib and can overcome tumor cell resistance mechanisms...
March 30, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28426830/correction-p16ink4a-expression-and-immunologic-aging-in-chronic-hiv-infection
#17
Susan Pereira Ribeiro, Jeffrey M Milush, Edecio Cunha-Neto, Esper G Kallas, Jorge Kalil, Luiz Felipe D Passero, Peter W Hunt, Steven G Deeks, Douglas F Nixon, Devi SenGupta
[This corrects the article DOI: 10.1371/journal.pone.0166759.].
2017: PloS One
https://www.readbyqxmd.com/read/28426648/pregnancy-swimming-causes-short-and-long-term-neuroprotection-against-hypoxia-ischemia-in-very-immature-rats
#18
Eduardo Farias Sanches, Luz Elena Duran Carabali, Andrea Tosta, Fabrício Nicola, Felipe Schmitz, André Rodrigues, Cassiana Siebert, Angela Wyse, Carlos Alexandre Netto
BACKGROUND: Hypoxia-ischemia (HI) is a major cause of neurological damage in preterm. Pregnancy swimming alters the pup's brain development. We tested the effects of swimming during pregnancy in the very immature rat brain. METHODS: Female Wistar rats (n=12) were assigned to sedentary (SE, n=6) or swimming groups (SW, n=6). From the gestational day 0 (DG0) to GD21 they performed 20 min/daily swimming sessions. HI on postnatal day 3 rat cause sensorimotor and cognitive impairments...
April 20, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28426003/a-temperate-rocky-super-earth-transiting-a-nearby-cool-star
#19
Jason A Dittmann, Jonathan M Irwin, David Charbonneau, Xavier Bonfils, Nicola Astudillo-Defru, Raphaëlle D Haywood, Zachory K Berta-Thompson, Elisabeth R Newton, Joseph E Rodriguez, Jennifer G Winters, Thiam-Guan Tan, Jose-Manuel Almenara, François Bouchy, Xavier Delfosse, Thierry Forveille, Christophe Lovis, Felipe Murgas, Francesco Pepe, Nuno C Santos, Stephane Udry, Anaël Wünsche, Gilbert A Esquerdo, David W Latham, Courtney D Dressing
M dwarf stars, which have masses less than 60 per cent that of the Sun, make up 75 per cent of the population of the stars in the Galaxy. The atmospheres of orbiting Earth-sized planets are observationally accessible via transmission spectroscopy when the planets pass in front of these stars. Statistical results suggest that the nearest transiting Earth-sized planet in the liquid-water, habitable zone of an M dwarf star is probably around 10.5 parsecs away. A temperate planet has been discovered orbiting Proxima Centauri, the closest M dwarf, but it probably does not transit and its true mass is unknown...
April 19, 2017: Nature
https://www.readbyqxmd.com/read/28425743/i-m-not-the-person-i-used-to-be-the-self-and-autobiographical-memories-of-immoral-actions
#20
Matthew L Stanley, Paul Henne, Vijeth Iyengar, Walter Sinnott-Armstrong, Felipe De Brigard
People maintain a positive identity in at least two ways: They evaluate themselves more favorably than other people, and they judge themselves to be better now than they were in the past. Both strategies rely on autobiographical memories. The authors investigate the role of autobiographical memories of lying and emotional harm in maintaining a positive identity. For memories of lying to or emotionally harming others, participants judge their own actions as less morally wrong and less negative than those in which other people lied to or emotionally harmed them...
April 20, 2017: Journal of Experimental Psychology. General
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