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https://www.readbyqxmd.com/read/28724004/international-cooperation-and-shortage-of-doctors-an-analysis-of-the-interaction-between-brazil-angola-and-cuba
#1
Sandra Mara Campos Alves, Felipe Proenço de Oliveira, Mateus Falcão Martins Matos, Leonor Maria Pacheco Santos, Maria Celia Delduque
The shortage of doctors, especially in remote areas, is a critical issue for the development of national health systems and has thus been the focus of a number of international cooperation projects. An exploratory and qualitative study was conducted to examine cooperation between Brazil, Angola and Cuba. A nonsystematic literature review was conducted of selected open access articles and official documents addressing relevant health cooperation initiatives. Previously selected characteristics of actions designed to redress the shortage of doctors were compared...
July 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/28723924/a-context-for-the-last-neandertals-of-interior-iberia-los-casares-cave-revisited
#2
Manuel Alcaraz-Castaño, Javier Alcolea-González, Martin Kehl, Rosa-María Albert, Javier Baena-Preysler, Rodrigo de Balbín-Behrmann, Felipe Cuartero, Gloria Cuenca-Bescós, Fernando Jiménez-Barredo, José-Antonio López-Sáez, Raquel Piqué, David Rodríguez-Antón, José Yravedra, Gerd-Christian Weniger
INTRODUCTION AND OBJECTIVES: Although the Iberian Peninsula is a key area for understanding the Middle to Upper Paleolithic transition and the demise of the Neandertals, valuable evidence for these debates remains scarce and problematic in its interior regions. Sparse data supporting a late Neandertal persistence in the Iberian interior have been recently refuted and hence new evidence is needed to build new models on the timing and causes of Neandertal disappearance in inland Iberia and the whole peninsula...
2017: PloS One
https://www.readbyqxmd.com/read/28722578/study-of-the-salivary-glands-in-triatominae-hemiptera-reduviidae-triatominae-their-color-and-application-to-the-chagas-disease-vector-evolution
#3
Jader de Oliveira, Amanda Ravazi, Eder Dos Santos Souza, Felipe Ferraz Figueiredo Moreira, Cleber Galvão, João Aristeu da Rosa, Kaio Cesar Chaboli Alevi
Chagas disease is caused by Trypanosoma cruzi and transmitted by feces of a triatomine that has the habit of defecating during blood feeding. The salivary glands of triatomines are important to hematophagy because their saliva is rich in anticoagulant and hemolytic proteins. The salivary glands of some Rhodnius species analyzed are reddish due to the presence of nitrophorins (antihemostatic activity). The present study aimed to analyze the color pattern of the salivary glands of 67 triatomine species to evaluate whether the presence of nitrophorins is a synapomorphy of Rhodnius or the tribe Rhodniini, or if it is shared with triatomines of the tribes Triatomini and Cavernicolini...
July 10, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28721747/faster-v%C3%AC-o2-kinetics-after-priming-exercises-of-different-duration-but-same-fatigue
#4
Felipe Mattioni Maturana, Arthur Peyrard, John Temesi, Guillaume Y Millet, Juan M Murias
This study compared the responses of two priming exercises of similar fatigue on the adjustment of the oxygen uptake time constant (τV̇O2) in cycling. Ten healthy young adults (25 ± 3 yr) performed: three step transitions from a 20-W baseline to the power output (PO) below the gas exchange threshold (MOD, MODPRE); a 3-min bout (P3MIN) at 90% of peak PO (POpeak), followed by MOD (MOD3MIN); and a 6-min bout (P6MIN) at 80% of POpeak, followed by MOD (MOD6MIN). The O2 supply-to-O2 demand ([HHb]/V̇O2) ratio was calculated for MODPRE, MOD3MIN, and MOD6MIN...
July 19, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28720975/active-starch-biopolymeric-packaging-film-for-sausages-embedded-with-essential-oil-of-syzygium-aromaticum
#5
Mariane L Ugalde, Aline M de Cezaro, Felipe Vedovatto, Natalia Paroul, Juliana Steffens, Eunice Valduga, Geciane T Backes, Elton Franceschi, Rogério L Cansian
Starch polymer matrices were developed with the incorporation of 1% clove essential oil (EO) (Syzygium aromaticum) aiming for use as active packaging for sausages. At the concentration of 1% EO in the polymer matrix, it showed exponential behavior with respect to oil release over 30 days, with faster release in the beginning and a tendency towards a reduction in release velocity over time. The presence of OE in the biofilm led to significant differences versus the control in terms of aroma and flavor parameters...
June 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28720787/comparison-between-an-african-town-and-a-neighbouring-village-shows-delayed-but-not-decreased-sleep-during-the-early-stages-of-urbanisation
#6
Andrew D Beale, Mario Pedrazzoli, Bruno da Silva B Gonçalves, Felipe Beijamini, Núbia E Duarte, Kieren J Egan, Kristen L Knutson, Malcolm von Schantz, Laura C Roden
The well-established negative health outcomes of sleep deprivation, and the suggestion that availability of electricity may enable later bed times without compensating sleep extension in the morning, have stimulated interest in studying communities whose sleep pattern may resemble a pre-industrial state. Here, we describe sleep and activity in two neighbouring communities, one urban (Milange) and one rural (Tengua), in a region of Mozambique where urbanisation is an ongoing process. The two communities differ in the amount and timing of daily activity and of light exposure, with later bedtimes (≈1 h) associated with more evening and less daytime light exposure seen in the town of Milange...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28720551/accelerating-permutation-testing-in-voxel-wise-analysis-through-subspace-tracking-a-new-plugin-for-snpm
#7
Felipe Gutierrez-Barragan, Vamsi K Ithapu, Chris Hinrichs, Camille Maumet, Sterling C Johnson, Thomas E Nichols, Vikas Singh
Permutation testing is a non-parametric method for obtaining the max null distribution used to compute corrected p-values that provide strong control of false positives. In neuroimaging, however, the computational burden of running such an algorithm can be significant. We find that by viewing the permutation testing procedure as the construction of a very large permutation testing matrix, T, one can exploit structural properties derived from the data and the test statistics to reduce the runtime under certain conditions...
July 15, 2017: NeuroImage
https://www.readbyqxmd.com/read/28720466/antinociceptive-effects-of-huf-101-a-fluorinated-cannabidiol-derivative
#8
Nicole R Silva, Felipe V Gomes, Miriam D Fonseca, Raphael Mechoulam, Aviva Breuer, Thiago M Cunha, Francisco S Guimarães
Cannabidiol (CBD) is a phytocannabinoid with multiple pharmacological effects and several potential therapeutic properties. Its low oral bioavailability, however, can limit its clinical use. Preliminary results indicate that fluorination of the CBD molecule increases its pharmacological potency. Here, we investigated whether HUF-101 (3, 10, and 30mg/kg), a fluorinated CBD analogue, would induce antinociceptive effects. HUF-101 effects were compared to those induced by CBD (10, 30, and 90mg/kg) and the cannabinoid CB1/2 receptor agonist WIN55,212-2 (1, 3, and 5mg/kg)...
July 15, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28720278/-development-of-a-liquid-fermentation-system-and-encystment-for-a-nitrogen-fixing-bacterium-strain-having-biofertilizer-potential
#9
Mauricio Camelo-Rusinque, Andrés Moreno-Galván, Felipe Romero-Perdomo, Ruth Bonilla-Buitrago
The indiscriminate use of chemical fertilizers has contributed to the deterioration of the biological, physical and chemical properties of the soil, resulting in the loss of its productive capacity. For this reason, the use of biofertilizers has emerged as a technological alternative. The objective of this research was to develop a suitable liquid fermentation system and encystment for the multiplication of Azotobacter chroococcum AC1 strain, a bacterium employed in a biofertilizer formulation produced at present by CARPOICA, Colombia...
July 15, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28719236/applying-an-artificial-neural-network-model-for-developing-a-severity-score-for-patients-with-hereditary-amyloid-polyneuropathy
#10
Shenia Novis, Felipe Machado, Victor B Costa, Debora Foguel, Marcia W Cruz, José Manoel de Seixas
Hereditary (familial) amyloid polyneuropathy (FAP) is a systemic disease that includes a sensorimotor polyneuropathy related to transthyretin (TTR) mutations. So far, a scale designed to classify the severity of this disease has not yet been validated. This work proposes the implementation of an artificial neural network (ANN) in order to develop a severity scale for monitoring the disease progression in FAP patients. In order to achieve this goal, relevant symptoms and laboratory findings were collected from 98 Brazilian patients included in THAOS - the Transthyretin Amyloidosis Outcomes Survey...
July 18, 2017: Amyloid: the International Journal of Experimental and Clinical Investigation
https://www.readbyqxmd.com/read/28719210/thermally-regulated-reversible-formation-of-vesicle-like-assemblies-by-hexaproline-amphiphiles
#11
Carles Felip-León, Francisco Galindo, Juan F Miravet, Valeria Castelletto, Ian W Hamley
Peptides composed of hexaproline and glutamic acid (P6E) or lysine (P6K) as C-terminal units show thermally promoted aggregation, affording vesicle-like assemblies upon heating to 80 ºC. The aggregation is analyzed by dynamic light scattering (DLS), with number averaged diameters of ca. 600 and 300 nm respectively for P6E and P6K. NMR studies reveal that upon heating the amount of NMR-visible species is reduced to ca. 50% and that an important conformational change is experienced by the molecules in solution...
July 18, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28719104/modeling-solvation-in-supercritical-co2
#12
Francesca Ingrosso, Manuel Felipe Ruiz-López
In the past decades, a microscopic understanding of the solute solvent intermolecular interactions has been key to advances in the technologies based on supercritical carbon dioxide (scCO2). In many cases, computational work has provided the impetus for new discoveries, shedding a new light on important concepts such as the local structure around the solute in the supercritical medium, the influence of the peculiar properties of the latter on the molecular behavior of dissolved substances and, importantly, CO2-philicity...
July 18, 2017: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/28718785/uv-surface-treatment-of-fungal-resistant-polyether-polyurethane-film-induced-growth-of-entomopathogenic-fungi
#13
Gabriela Albara Lando, Letícia Marconatto, Felipe Kessler, William Lopes, Augusto Schrank, Marilene Henning Vainstein, Daniel Eduardo Weibel
Synthetic polymers are the cause of some major environmental impacts due to their low degradation rates. Polyurethanes (PU) are widely used synthetic polymers, and their growing use in industry has produced an increase in plastic waste. A commercial polyether-based thermoplastic PU with hydrolytic stability and fungus resistance was only attacked by an entomopathogenic fungus, Metarhiziumanisopliae, when the films were pre-treated with Ultraviolet (UV) irradiation in the presence of reactive atmospheres. Water contact angle, Fourier transform infrared spectroscopy in attenuated total reflection mode (FTIR-ATR), scanning electron microscopy (SEM), and profilometer measurements were mainly used for analysis...
July 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28717669/pitfalls-in-genetic-testing-a-case-of-a-snp-in-primer-annealing-region-leading-to-allele-dropout-in-brca1
#14
Felipe Carneiro Silva, Giovana Tardin Torrezan, Rafael Canfield Brianese, Raquel Stabellini, Dirce Maria Carraro
BACKGROUND: Hereditary breast and ovarian cancer is characterized by mutations in BRCA1 or BRCA2 genes and PCR-based screening techniques, such as capillary sequencing and next-generation sequencing (NGS), are considered gold standard methods for detection of pathogenic mutations in these genes. Single-nucleotide polymorphisms (SNPs) constitute a vast source of variation in the human genome and represent a risk for misdiagnosis in genetic testing, since the presence of a SNP in primer-annealing sites may cause false negative results due to allele dropout...
July 2017: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/28717645/whole-genome-amplification-of-day-3-or-day-5-human-embryos-biopsies-provides-a-suitable-dna-template-for-pcr-based-techniques-for-genotyping-a-complement-of-preimplantation-genetic-testing
#15
Elizabeth Schaeffer, Bruno López-Bayghen, Adina Neumann, Leonardo M Porchia, Rafael Camacho, Efraín Garrido, Rocío Gómez, Felipe Camargo, Esther López-Bayghen
Our objective was to determine if whole genome amplification (WGA) provides suitable DNA for qPCR-based genotyping for human embryos. Single blastomeres (Day 3) or trophoblastic cells (Day 5) were isolated from 342 embryos for WGA. Comparative Genomic Hybridization determined embryo sex as well as Trisomy 18 or Trisomy 21. To determine the embryo's sex, qPCR melting curve analysis for SRY and DYS14 was used. Logistic regression indicated a 4.4%, 57.1%, or 98.8% probability of a male embryo when neither gene, SRY only, or both genes were detected, respectively (accuracy = 94...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28716970/prolonged-force-depression-after-mechanically-demanding-contractions-is-largely-independent-of-ca-2-and-reactive-oxygen-species
#16
Sigitas Kamandulis, Felipe de Souza Leite, Andres Hernández, Abram Katz, Marius Brazaitis, Joseph D Bruton, Tomas Venckunas, Nerijus Masiulis, Dalia Mickeviciene, Nerijus Eimantas, Andrejus Subocius, Dilson E Rassier, Albertas Skurvydas, Niklas Ivarsson, Håkan Westerblad
Increased production of reactive oxygen/nitrogen species (ROS) and impaired cellular Ca(2+) handling are implicated in the prolonged low-frequency force depression (PLFFD) observed in skeletal muscle after both metabolically and mechanically demanding exercise. Metabolically demanding high-intensity exercise can induce PLFFD accompanied by ROS-dependent fragmentation of the sarcoplasmic reticulum Ca(2+) release channels, the ryanodine receptor (RyR)-1. We tested whether similar changes occur after mechanically demanding eccentric contractions...
July 17, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28716960/bacterial-tubulin-a-b-exhibit-polarized-growth-mixed-polarity-bundling-and-destabilization-by-gtp-hydrolysis
#17
César Díaz-Celis, Viviana I Risca, Felipe Hurtado, Jessica K Polka, Scott D Hansen, Daniel Maturana, Rosalba Lagos, R Dyche Mullins, Octavio Monasterio
Bacteria of the genus Prosthecobacter express homologs of eukaryotic α- and β-tubulin, called BtubA and BtubB, that have been observed to assemble into filaments in presence of GTP. BtubA/B polymers are proposed to be composed in vitro by two to six protofilaments, in contrast to in vivo where they have been reported to form 5-protofilaments tubes named bacterial microtubules (bMTs). The btubAB genes likely entered the Prosthecobacter lineage via horizontal gene transfer and may derive from an early ancestor of the modern eukaryotic microtubule (MT)...
July 17, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28715118/microrna159-targeted-slgamyb-transcription-factors-are-required-for-fruit-set-in-tomato
#18
Eder Marques da Silva, Geraldo Felipe Ferreira E Silva, Débora Brussolo Bidoia, Mariana da Silva Azevedo, Frederico Almeida de Jesus, Lilian Ellen Pino, Lázaro Eustáquio Pereira Peres, Esther Carrera, Isabel López-Díaz, Fabio Tebaldi Silveira Nogueira
The transition from flowering to fruit production, namely fruit set, is crucial to ensure successful sexual plant reproduction. Although studies have described the importance of hormones (i.e., auxin and gibberelins) in controlling fruit set after pollination and fertilization, the role of microRNA-based regulation during ovary development and fruit set is still poorly understood. Here we show that microRNA159/GAMYB1 and -2 pathway (the miR159/GAMYB1/2 module) is crucial for tomato ovule development and fruit set...
July 17, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/28713688/childhood-trauma-and-factors-associated-with-depression-among-inpatients-with-cardiovascular-disease
#19
Felipe José Nascimento Barreto, Frederico Duarte Garcia, Paulo Henrique Teixeira Prado, Paulo Marcos Brasil Rocha, Nádia Souza Las Casas, Felipe Barbosa Vallt, Humberto Correa, Maila Castro Lourenço Neves
AIM: To identify factors associated with depressive symptoms among inpatients with cardiovascular disease (CVD). METHODS: This is a cross-sectional study performed in a subsample of a large cross-sectional research that investigated affective disorders and suicide behaviour among inpatients hospitalized in non-surgical wards of the University Hospital of the Federal University of Minas Gerais from November 2013 to October 2015. Sociodemographic and clinical data were obtained through a structured interview and medical record review...
June 22, 2017: World Journal of Psychiatry
https://www.readbyqxmd.com/read/28713471/assessment-of-specificity-of-the-badcamp-agility-test-for-badminton-players
#20
Luiz de França Bahia Loureiro, Mário Oliveira Costa Dias, Felipe Couto Cremasco, Maicon Guimarães da Silva, Paulo Barbosa de Freitas
The Badcamp agility test was created to evaluate agility of badminton players. The Badcamp is a valid and reliable test, however, a doubt about the need for the use of this test exists as simpler tests could provide similar information about agility in badminton players. Thus, the aim of this study was to examine the specificity of the Badcamp, comparing the performance of badminton players and athletes from other sports in the Badcamp and the shuttle run agility test (SRAT). Sixty-four young male and female athletes aged between 14 and 16 years participated in the study...
June 2017: Journal of Human Kinetics
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