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Eosinophilic meningitis

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https://www.readbyqxmd.com/read/29668140/-standardization-of-a-multiplex-real-time-pcr-test-for-the-identification-of-angiostrongylus-cantonensis-a-costaricensis-and-a-vasorum
#1
Rubén E Varela-M, Jinney Stefany Arias, Luz Elena Velásquez
INTRODUCTION: Angiostrongyliasis is a disease caused by Angiostrongylus nematodes that is present worldwide. The infections with the highest impact on human and animal health are caused by A. cantonensis, A. costaricensis, and A. vasorum. Clinical forms of the disease in humans are eosinophilic meningitis and abdominal angiostrongyliasis, while the most common effect on dogs are cardiopulmonary damages. It is deemed as an emerging disease as the result of the global dissemination of the African snail Lissachatina fulica, an intermediary host of these parasites...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29616650/pediatric-angiostrongyliasis
#2
F Lombard, D Basset, G Cambonie, P Bastien, E Jeziorski
Angiostrongyliasis, the leading cause worldwide of eosinophilic meningitis, is an emergent disease due to Angiostrongylus cantonensis larvae, transmitted accidentally to humans. Contamination of children usually occurs by direct contact with an infected mollusk. Eosinophilic meningoencephalitis is the major clinical feature of this parasitic infection in humans. It is usually benign for adults, but more severe for children. Clinical symptoms usually combine fever, meningitis, and neurological signs (somnolence, moaning, hypotonia, convulsions, and increased intracranial pressure)...
February 1, 2018: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29603737/clinical-presentation-and-magnetic-resonance-imaging-findings-in-11-dogs-with-eosinophilic-meningoencephalitis-of-unknown-aetiology
#3
T J A Cardy, I Cornelis
OBJECTIVES: To describe the clinical presentation, MRI findings and outcome in dogs with eosinophilic meningoencephalitis of unknown origin. MATERIALS AND METHODS: Dogs were included in this retrospective study if they had complete medical records, complete neurological examination, MR imaging, cerebellomedullary cerebrospinal fluid sample consistent with eosinophilic pleocytosis and negative infectious disease testing. RESULTS: Eleven dogs were included with a median age of 22·0 months (range 7·6 to 92·0 months)...
March 30, 2018: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/29574000/invasive-pomacea-snails-as-important-intermediate-hosts-of-angiostrongylus-cantonensis-in-laos-cambodia-and-vietnam-implications-for-outbreaks-of-eosinophilic-meningitis
#4
Shan Lv, Yun-Hai Guo, Hung Manh Nguyen, Muth Sinuon, Somphou Sayasone, Nathan C Lo, Xiao-Nong Zhou, Jason R Andrews
The rat lungworm Angiostrongylus cantonensis causes human eosinophilic meningitis and it is endemic in Southeast Asia, but little is known about its distribution in Laos, Cambodia and Vietnam. We conducted a multi-country survey for A. cantonensis in these countries to estimate its prevalence in snails along the Mekong River and the east coast of Vietnam. We identified Angiostrongylus species by morphological and molecular analysis. We found A. cantonensis in the invasive snail, Pomacea spp. The wide accessibility of Pomacea snails, along with their infection by A...
March 21, 2018: Acta Tropica
https://www.readbyqxmd.com/read/29547198/chronic-eosinophilic-meningitis-as-a-manifestation-of-isolated-spinal-neurocysticercosis-a-rare-case-and-a-review-of-literature
#5
Abhinith Shashidhar, Amey R Savardekar, Ravindranadh C Mundlamuri, M Netravathi, A Nalini, Yasha T Chickabasaviah, A Arivazhagan, Malla Bhaskar Rao
No abstract text is available yet for this article.
March 2018: Neurology India
https://www.readbyqxmd.com/read/29451597/achatina-fulica-infected-by-angiostrongylus-cantonensis-on-beaches-in-the-west-zone-of-rio-de-janeiro-brazil
#6
André H Bechara, Raquel O Simões, Marta Júlia Faro, Juberlan S Garcia
Angiostrongylus cantonensis is considered the main etiological agent of eosinophilic meningitis in humans. At present, this zoonosis is considered an emerging disease mainly in the Americas. The aim of this study was to determine the prevalence of Achatina fulica infected by Angiostrongylus cantonensis in restinga areas along beaches in the west zone of Rio de Janeiro city, Brazil. The study areas included the following beaches: Barra da Tijuca, Recreio dos Bandeirantes, Reserva, Prainha and Grumari. Ninety specimens of Achatina fulica were collected...
2018: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29438532/a-child-with-intermittent-headaches-and-eosinophilic-meningitis
#7
Sara R Saporta-Keating, Eric A F Simões, Guixia Yu, Scot Federman, David Mirsky, Samuel R Dominguez, Charles Y Chiu, Kevin Messacar
No abstract text is available yet for this article.
February 9, 2018: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29411969/diagnosing-and-understanding-angiostrongyliasis-a-zoonotic-cause-of-meningitis
#8
Carlos Graeff-Teixeira, Alessandra Loureiro Morassutti, Malcolm K Jones
Eosinophilic meningitis caused by Angiostrongylus cantonensis is spreading worldwide, and it can manifest as a severe neurological disease. Angiostrongyliasis is a food- and water-borne parasitosis that usually exhibits a seasonal and circumscribed geographical distribution. To improve control and treatment of these infections, further studies of transmission dynamics under natural conditions and the development of better diagnostic tools and treatment options are needed.
February 7, 2018: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/29408878/the-endocannabinoid-system-in-canine-steroid-responsive-meningitis-arteritis-and-intraspinal-spirocercosis
#9
Jessica Freundt-Revilla, Franciska Heinrich, Alexander Zoerner, Felix Gesell, Martin Beyerbach, Merav Shamir, Anna Oevermann, Wolfgang Baumgärtner, Andrea Tipold
Endocannabinoids (ECs) are involved in immunomodulation, neuroprotection and control of inflammation in the central nervous system (CNS). Activation of cannabinoid type 2 receptors (CB2) is known to diminish the release of pro-inflammatory factors and enhance the secretion of anti-inflammatory cytokines. Furthermore, the endocannabinoid 2-arachidonoyl glycerol (2-AG) has been proved to induce the migration of eosinophils in a CB2 receptor-dependent manner in peripheral blood and activate neutrophils independent of CB activation in humans...
2018: PloS One
https://www.readbyqxmd.com/read/29391024/chi3l3-a-potential-key-orchestrator-of-eosinophil-recruitment-in-meningitis-induced-by-angiostrongylus-cantonensis
#10
Shuo Wan, Xiaoqiang Sun, Feng Wu, Zilong Yu, Lifu Wang, Datao Lin, Zhengyu Li, Zhongdao Wu, Xi Sun
BACKGROUND: Angiostrongylus cantonensis, an important foodborne parasite, can induce serious eosinophilic meningitis in non-permissive hosts, such as mouse and human. However, the characteristics and mechanisms of the infection are still poorly understood. This study sought to determine the key molecules and its underlying mechanism in inducing brain eosinophilic infiltration caused by Angiostrongylus cantonensis. METHODS: Mathematical models were established for prediction of significantly changing genes and the functional associated protein with RNA-seq data in Angiostrongylus cantonensis infection...
February 2, 2018: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/29258580/apoptosis-and-necroptosis-of-mouse-hippocampal-and-parenchymal-astrocytes-microglia-and-neurons-caused-by-angiostrongylus-cantonensis-infection
#11
Zhang Mengying, Xu Yiyue, Pan Tong, Hu Yue, Yanin Limpanont, Huang Ping, Kamolnetr Okanurak, Wu Yanqi, Paron Dekumyoy, Zhou Hongli, Dorn Watthanakulpanich, Wu Zhongdao, Wang Zhi, Lv Zhiyue
BACKGROUND: Angiostrongylus cantonensis has been the only parasite among Angiostrongylidae to cause human central nervous system infection characterized by eosinophilic meningitis or meningoencephalitis. The mechanism of the extensive neurological impairments of hosts caused by A. cantonensis larvae remains unclear. The aim of the present study was to investigate apoptosis, necroptosis and autophagy in the brains of mice infected with A. cantonensis, which will be valuable for better understanding the pathogenesis of angiostrongyliasis cantonensis...
December 19, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29148389/angiostrongylus-cantonensis-dna-in-cerebrospinal-fluid-of-persons-with-eosinophilic-meningitis-laos
#12
Damien K Y Ming, Sayaphet Rattanavong, Tehmina Bharucha, Onanong Sengvilaipaseuth, Audrey Dubot-Pérès, Paul N Newton, Matthew T Robinson
Definitive identification of Angiostrongylus cantonensis parasites from clinical specimens is difficult. As a result, regional epidemiology and burden are poorly characterized. To ascertain presence of this parasite in patients in Laos with eosinophilic meningitis, we performed quantitative PCRs on 36 cerebrospinal fluid samples; 4 positive samples confirmed the parasite's presence.
December 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28989050/novel-application-of-time-spatial-labeling-inversion-pulse-magnetic-resonance-imaging-for-diagnosis-of-external-hydrocephalus
#13
Shunsuke Nakae, Kazuhiro Murayama, Kazuhide Adachi, Tadashi Kumai, Masato Abe, Yuichi Hirose
BACKGROUND: Although a subdural fluid collection frequently is observed, diagnostic methods that differentiate between the subdural collection caused by external hydrocephalus and that caused by subdural hygroma have not been established. Here, we report a case of external hydrocephalus caused by Gliadel-induced eosinophilic meningitis that has been previously reported in only 1 case and can be diagnosed by time-spatial labeling inversion pulse magnetic resonance imaging (time-SLIP MRI)...
January 2018: World Neurosurgery
https://www.readbyqxmd.com/read/28953426/proteomic-analysis-of-differentially-expressed-proteins-in-intracranial-angiostrongylus-cantonensis-larvae-in-permissive-and-non-permissive-hosts
#14
Dan She, Xin Zhang, Zexun Mo, Guilan Yang, Jyh-Wei Shin, Xiaoguang Chen, Liwang Cui, Hua Li
Angiostrongylus cantonensis infection can lead to severe neuropathological damage caused by the development of these nematodes in the central nervous system after penetrating the blood-brain barrier. They commonly cause eosinophilic meningitis or meningoencephalitis in non-permissive hosts (e.g., mice). It has been shown that differences exist in the brains of permissive and non-permissive hosts during the larval development of A. cantonensis; however, the mechanism underlying the difference is not completely understood...
December 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28950910/stimulation-of-il-1%C3%AE-and-il-6-through-nf-%C3%AE%C2%BAb-and-sonic-hedgehog-dependent-pathways-in-mouse-astrocytes-by-excretory-secretory-products-of-fifth-stage-larval-angiostrongylus-cantonensis
#15
Kuang-Yao Chen, Lian-Chen Wang
BACKGROUND: Angiostrongylus cantonensis is an important causative agent of eosinophilic meningitis and eosinophilic meningoencephalitis in humans. Previous studies have shown that the Sonic hedgehog (Shh) signaling pathway may reduce cell apoptosis by inhibiting oxidative stress in A. cantonensis infection. In this study, we investigated the relationship between cytokine secretion and Shh pathway activation after treatment with excretory/secretory products (ESP) of fifth-stage larval A...
September 26, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28947512/closing-the-brief-case-angiostrongylus-cantonensis-eosinophilic-meningitis-in-a-returned-traveler
#16
EDITORIAL
Kunatum Prasidthrathsint, Julia Lewis, Marc Roger Couturier
No abstract text is available yet for this article.
October 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28947508/the-brief-case-angiostrongylus-cantonensis-eosinophilic-meningitis-in-a-returned-traveler
#17
EDITORIAL
Kunatum Prasidthrathsint, Julia Lewis, Marc Roger Couturier
No abstract text is available yet for this article.
October 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28930003/angiostrongylus-cantonensis-eosinophilic-meningitis-in-an-infant-tennessee-usa
#18
Tim Flerlage, Yvonne Qvarnstrom, John Noh, John P Devincenzo, Arshia Madni, Bindiya Bagga, Nicholas D Hysmith
Angiostrongylus cantonensis, the rat lungworm, is the most common infectious cause of eosinophilic meningoencephalitis worldwide. This parasite is endemic to Southeast Asia and the Pacific Islands, and its global distribution is increasing. We report A. cantonensis meningoencephalitis in a 12-month-old boy in Tennessee, USA, who had not traveled outside of southwestern Tennessee or northwestern Mississippi.
October 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28859686/the-genetic-variation-of-angiostrongylus-cantonensis-in-the-people-s-republic-of-china
#19
Shan Lv, Yi Zhang, Peter Steinmann, Jürg Utzinger, Xiao-Nong Zhou
BACKGROUND: The People's Republic of China (P.R. China) is the presumptive home range of the rat lungworm Angiostrongylus cantonensis, a major aetiological agent of human eosinophilic meningitis. We present a study of the genetic variation of A. cantonensis in P.R. China. Our aim was to deepen the current knowledge pertaining to its origin and global spread from a molecular perspective. METHODS: Adult A. cantonensis were collected in the frame of a national survey and identified based on morphological criteria...
September 1, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28827809/phylogeography-of-angiostrongylus-cantonensis-nematoda-angiostrongylidae-in-southern-china-and-some-surrounding-areas
#20
Jian Peng, Zhang-Ping He, Shuai Zhang, Zhao-Rong Lun, Zhong-Dao Wu, Chia-Kwung Fan, Christopher L Brown, Po-Ching Cheng, Shih-Yi Peng, Ting-Bao Yang
Angiostrongylus cantonensis is of increasing public health importance as the main zoonotic pathogen causing eosinophilic meningitis or meningoencephalitis, which has been documented all over the world. However, there are very limited studies about its phylogeography and spread pattern. In the present study, the phylogeography of A. cantonensis in southern China (including Taiwan) and partial areas of Southeast Asia were studied based on the sequences of complete mitochondrial cytochrome b (Cytb) gene. A total of 520 individuals of A...
August 2017: PLoS Neglected Tropical Diseases
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