EPAT

IMPORTANCE: Epicardial and pericardial adipose tissue (EPAT) has been associated with cardiovascular diseases such as atrial fibrillation or flutter (AF) and coronary artery disease (CAD), but studies have been limited in sample size or drawn from selected populations. It has been suggested that the association between EPAT and cardiovascular disease could be mediated by local or paracrine effects. OBJECTIVE: To evaluate the association of EPAT with prevalent and incident cardiovascular disease and to elucidate the genetic basis of EPAT in a large population cohort...

PURPOSE: In the absence of a standardized tool to assess the quality of pediatric hematology/oncology training programs, the Education Program Assessment Tool (EPAT) was conceptualized as a user-friendly and adaptable tool to evaluate and identify areas of opportunity, pinpoint needed modifications, and monitor progress for training programs around the world. METHODS: The development of EPAT consisted of three main phases: operationalization, consensus, and piloting...

Recent clinical evidence has suggested that interatrial septal (IAS) adiposity contributes to atrial fibrillation (AF). The present study aimed to confirm the usefulness of transesophageal echocardiography (TEE) to estimate IAS adiposity in patients with AF. The histological IAS analysis based on autopsy samples sought to clarify characteristics that underlie the contribution of IAS adiposity to AF. The imaging study analyzed the TEE results in patients with AF (n = 184) in comparison with transthoracic echocardiography (TTE) and computed tomography (CT) results...

OBJECTIVES: To understand individual prescribing and associated costs in patients managed with the Edinburgh Pain Assessment and management Tool (EPAT). METHODS: The EPAT study was a two-arm parallel group cluster randomised (1:1) trial, including 19 UK cancer centres. Study outcome assessments, including pain levels, analgesia and non-pharmacological and anaesthetic interventions, collected at baseline, 3-5 days and, if applicable, 7-10 days after admission...

The obesity epidemic is associated with increased colorectal cancer (CRC) risk and progression, the mechanisms of which remain unclear. In obese individuals, hypertrophic epiploic adipose tissue (EPAT), attached to the colon, has unique characteristics compared to other fats. We hypothesized that this understudied fat could serve as a tumor-promoting tissue and developed a novel microphysiological system (MPS) for human EPAT-dependent colorectal cancer (CRC-MPS). In CRC-MPS, obese EPAT, unlike lean EPAT, considerably attracted colon cancer HT29-GFP cells and enhanced their growth...

OBJECTIVES: Epicardial adipose tissue (EpAT) is known for its role in supporting the cardiomyocytes. Lysine-specific demethylase 1 (LSD1), a typical lysine demethylase, is an essential regulator for the maintenance of beige adipocytes. However, the effect of LSD1 in the adipogenic differentiation of beige adipocytes in EpAT, and its function on oxygen and glucose deprivation (OGD)-injured cardiomyocytes remain unclear. MATERIALS AND METHODS: Heart tissues from young mice and elder mice were collected for immunohistochemical staining...

Enhancing energy efficiency is an important issue for countries facing pressures from energy shortages and environment pollution. Given increasing interest in the role of environmental supervision and the current lack of empirical evidence on this topic, this study investigates the impact of environmental supervision on firms' energy efficiency by taking the Environmental Protection Admonishing Talk (EPAT) policy in China as a quasi-natural experiment. Using the difference-in-differences method and the panel data of more than 3 million firms in China from 2008 to 2016, we find that environmental supervision improves firms' energy efficiency...

Endoscopic photoacoustic tomography (EPAT) is a catheter-based hybrid imaging modality capable of providing structural and functional information of biological luminal structures, such as coronary arterial vessels and the digestive tract. The recovery of the optical properties of the imaged tissue from acoustic measurements achieved by optical inversion is essential for implementing quantitative EPAT (qEPAT). In this paper, a convolutional neural network (CNN) based on deep gradient descent is developed for qEPAT...

INTRODUCTION: To effectively foster patient-centeredness (PC), it is crucial to measure its implementation. So far, there is no German measure to assess PC comprehensively. The aim of this study is to develop and select items for the Experienced Patient-Centeredness (EPAT) Questionnaire, a patient-reported experience measure (PREM). The EPAT intends to assess PC from the perspective of adult patients treated for different chronic diseases in inpatient and outpatient settings in Germany...

BACKGROUND: In endoscopic photoacoustic tomography (EPAT), the photoacoustically induced ultrasonic wave reflects at tissue boundaries due to the acoustic inhomogeneity of the imaged tissue, resulting in reflection artifacts (RAs) in the reconstructed images. OBJECTIVE: To suppress RAs in EPAT image reconstruction for improving the image quality. METHODS: A method was presented to render the cross-sectional images of the optical absorption with reduced RAs from acoustic measurements...

Background: This paper presents the case study of a health campaign for mobile devices launched in Italy in 2019 aimed at raising viral hepatitis awareness. The research project " ABC epatite. Sviluppo di una app per la prevenzione delle epatiti virali e per la consapevolezza dei comportamenti a rischio ", winner of the 2018 Digital Health Program of Gilead Italia, was carried out by the Italian National Research Council. Methods: The project entailed the development of a free Italian language Progressive Web App (PWA) providing current and scientifically validated information on viral hepatitis (A, B and C)...

PURPOSE: The Affordable Care Act (ACA), enacted in 2010, created the Expansion of Physician Assistant Training (EPAT) grant with the goal of increasing the number of physician assistants (PAs) entering primary care. There has been no analysis regarding the practice patterns of students graduating from EPAT-funded programs. This study aimed to describe the workforce impact of federal investment in PA education through the EPAT program. METHODS: In 2018 the authors administered an anonymous electronic survey to all 27 EPAT PA programs funded from 2010 to 2015...

BACKGROUND: Hepatocellular carcinoma (HCC) is the most common primary liver malignancy that is strongly associated with chronic liver disease. Isolated hepatic tuberculosis is an uncommon type of tuberculosis. Concomitant occurrence of both conditions is extremely rare. CASE PRESENTATION: We report the case of a 47-year-old man who presented with fever and abdominal pain for 3 months prior to presentation. He reported a history of anorexia and significant weight loss...

BACKGROUND: Clinical studies have reported that epicardial adipose tissue (EpAT) accumulation associates with the progression of atrial fibrillation (AF) pathology and adversely affects AF management. The role of local cardiac EpAT deposition in disease progression is unclear, and the electrophysiological, cellular, and molecular mechanisms involved remain poorly defined. OBJECTIVES: The purpose of this study was to identify the underlying mechanisms by which EpAT influences the atrial substrate for AF...

Endoscopic photoacoustic tomography (EPAT) is an interventional application of photoacoustic tomography (PAT) to visualize anatomical features and functional components of biological cavity structures such as nasal cavity, digestive tract or coronary arterial vessels. One of the main challenges in clinical applicability of EPAT is the incomplete acoustic measurements due to the limited detectors or the limited-view acoustic detection enclosed in the cavity. In this case, conventional image reconstruction methodologies suffer from significantly degraded image quality...

BACKGROUND: Minimally invasive intragastric surgery [IGS] was first described by Ohashi in 1995 for early gastric cancer, with 3 trocars placed in the gastric lumen. Prior abdominal surgery is not a contraindication to IGS while the abdominal cavity is not explored, always that exist transilumination. But conversion to laparoscopic and open surgery can be challenging owing to the insufflated stomach and/or small bowel, although gas can be easily released via the gastrostomy. CASE PRESENTATION: A 53-year-old female patient, presented with a sub epithelial gastric antrum lesion confirmed by endoscopic ultrasonography managed with surgical endoscopic percutaneous assisted transgastric technique [EPATS] using a gastrostomy tube and the endoscope...

External volume expansion (EVE) is an effective method of adipose tissue regeneration. However, it remains unclear how EVE induces adipose tissue regeneration. Here, we developed EVE devices to generate expanded prefabricated adipose tissue (EPAT) in rats and investigated cell proliferation, adipogenesis and the expression of extracellular matrix (ECM) proteins during the 12 weeks suction. In addition, EPAT-generated decellularized adipose tissue (DAT) was used to assess the role of ECM proteins in cell proliferation and differentiation...

BACKGROUND: Plantar fasciitis is one of the most common clinical presentations seen by podiatric clinicians today. With corticosteroid injection being a classic treatment modality and extracorporeal pulse-activated therapy (EPAT) technology improving, the purpose of this study was to retrospectively compare pain and functional outcomes of patients with plantar fasciitis treated with either injection or EPAT. METHODS: Between November 1, 2014, and April 30, 2016, 60 patients who met the inclusion criteria were treated with either corticosteroid injection or EPAT...

The idealized assumption of a constant speed of sound (SOS) in acoustically inhomogeneous biological tissues usually results in blurred details, acoustic distortion and artifacts in in vivo endoscopic photoacoustic tomographic (EPAT) images. In this paper, we propose an image reconstruction method to improve EPAT imaging for luminal structures with the variable SOS. In our method, an optimal SOS providing the maximal local focusing of a measuring location within the imaging region is firstly determined. The deviation in the ultrasonic propagation time caused by the variable SOS is then compensated...

OBJECTIVE: In this systematic review, we aim to synthesize the literature on the use of natural language processing (NLP) and text mining as they apply to symptom extraction and processing in electronic patient-authored text (ePAT). MATERIALS AND METHODS: A comprehensive literature search of 1964 articles from PubMed and EMBASE was narrowed to 21 eligible articles. Data related to purpose, text source, number of users and/or posts, evaluation metrics, and quality indicators were recorded...