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Invasive fungal sinusitis

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https://www.readbyqxmd.com/read/28797492/fungal-infections-after-lung-transplantation
#1
REVIEW
Cassie C Kennedy, Raymund R Razonable
Infection remains a significant source of morbidity and mortality after lung transplant, including fungal infection. Various antifungal prophylactic agents are administered for a variable duration after transplant with the goal of preventing invasive fungal infections. Alternatively, some programs target the use of antifungal agents only in those colonized with Aspergillus spp. Despite prophylaxis or preemptive therapy, a significant number of invasive fungal infections occur after lung transplant. Risk factors for fungal infections include single lung transplant, pretransplant Aspergillus colonization, environmental risks, structural lung disease such as cystic fibrosis, augmented immunosuppression, sinus disease, and use of indwelling airway stents...
September 2017: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/28774699/pulmonary-and-sinus-fungal-diseases-in-non-immunocompromised-patients
#2
REVIEW
David W Denning, Arunaloke Chakrabarti
The human respiratory tract is exposed daily to airborne fungi, fungal enzymes, and secondary metabolites. The endemic fungi Histoplasma capsulatum, Coccidioides spp, Blastomyces dermatitidis, and Paracoccidioides brasiliensis, and occasionally Aspergillus fumigatus, are primary pulmonary pathogens of otherwise healthy people. Such infections resolve in most people, and only a few infections lead to disease. However, many fungi are directly allergenic by colonising the respiratory tract or indirectly through contact with cell wall constituents and proteases, causing or exacerbating allergic disease...
July 31, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28770205/fatal-mycotic-aneurysm-of-the-basilar-artery-caused-by-aspergillus-fumigatus-in-a-patient-with-pituitary-adenoma-and-meningitis
#3
Martin Winterholler, Roland Coras, Walter Geißdörfer, Rudolf Rammensee, Philipp Gölitz, Christian Bogdan, Roland Lang
Fungal infections of the central nervous system (CNS) frequently occur in immunosuppressed patients. Here, we describe the case of an immunocompetent 64-year-old man who presented with diplopia, right-sided hemiparesis, and a mild headache after cleaning and replacing nesting boxes of wild birds during the preceding months. Lumbar puncture revealed pleocytosis, elevated protein, and lactate levels in the cerebrospinal fluid (CSF). Initial imaging showed ischemia in the left thalamus and an enlargement of the sellar region...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28748192/extranodal-nk-t-cell-lymphoma-nasal-type-presenting-as-refractory-pseudomonas-aeruginosa-facial-cellulitis
#4
Erika Reategui Schwarz, Katerina G Oikonomou, Megan Reynolds, Juliette Kim, Rajeev L Balmiki, Stephanie A Sterling
Extranodal natural killer T-cell lymphoma, nasal type (ENKL), formerly called lethal midline granuloma or angiocentric T-cell lymphoma, is a predominantly extranodal non-Hodgkin lymphoma characterized by vascular damage, necrosis, and an association with Epstein-Barr virus. In the United States, it is more frequently seen in Asian, Asian Pacific Islander, and Hispanic descent populations and is more prevalent in males in their fifth decade. Clinical presentation of NK nasal lymphoma most commonly involves epistaxis; obstruction; discharge; destructive mass in sinuses, palate, and nose; and skin ulceration...
July 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28747616/assessment-of-non-invasive-chronic-fungal-rhinosinusitis-by-cone-beam-ct-comparison-with-multidetector-ct-findings
#5
Tomohiko Yamauchi, Akiko Tani, Shuji Yokoyama, Hiroshi Ogawa
OBJECTIVE: To investigate the accuracy of cone beam CT (CBCT) to diagnose non-invasive chronic fungal rhinosinusitis. METHODS: Preoperative CT evaluation of non-invasive chronic fungal rhinosinusitis was performed by CBCT (3D Accuitomo 170(®)) and traditional multidetector CT (MDCT) (Aquilion 32(®)) in 13 and 38 patients with non-invasive chronic fungal maxillary sinusitis, respectively, in different facilities. Detection of intrasinus calcification was compared between these two groups...
July 26, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28707783/aggressive-necrotizing-pseudomonal-sinonasal-infections
#6
Edward C Kuan, Bobby A Tajudeen, Kevin C Welch, Rakesh K Chandra, Ben J Glasgow, Jeffrey D Suh
BACKGROUND: Pseudomonas aeruginosa is a gram-negative bacterium frequently implicated in recalcitrant sinonasal infections, especially in immunocompromised hosts. We report 6 cases of rapidly progressive pseudomonal acute rhinosinusitis producing tissue necrosis and, in certain cases, cranial nerve palsies. METHODS: Retrospective review of 6 patients with aggressive necrotizing sinonasal infections treated at 4 tertiary academic medical centers with sinonasal cultures growing P...
July 14, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28705685/-fungal-sinusitis
#7
REVIEW
E Lafont, C Aguilar, P Vironneau, R Kania, A Alanio, S Poirée, O Lortholary, F Lanternier
Although sinusitis affects about 20 % of the population, fungal sinusitis is rare. Aspergillus sp. are most frequently implicated. Fungal sinusitis represents a wide spectrum of disorders, including acute or chronic and invasive or non-invasive forms. Invasive fungal sinusitis may develop in an immunocompromised or diabetic patient, whereas non-invasive fungal sinusitis should be considered in a chronic situation, resistant to antibiotics in immunocompetent patients. Allergic fungal sinusitis is related to hypersensitivity of the host to the fungus...
June 2017: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/28636087/extended-inferior-antrostomy-for-maxillary-sinus-surgery
#8
Justin Michel, Thomas Radulesco, Martin Penicaud, Patrick Dessi
Functional endoscopic sinus surgery (FESS) has considerably evolved over the past 20 years while minimally-invasive surgery also applies to sinus procedures. Development of new technologies combined with better knowledge of risks has allowed surgeons to achieve improved results in their FESS indications. One of the most difficult areas to visualize using the exclusive endoscopic approach is still the anterior recess of the maxillary sinus. Hence, external approaches, such as the Caldwell-Luc procedure, are still used by many surgeons to ensure visual control of this area in diseases such as fungal balls, mucoceles, inverted papilloma and other tumors...
June 21, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28622118/imaging-spectrum-of-invasive-fungal-and-fungal-like-infections
#9
Hilary L P Orlowski, Sebastian McWilliams, Vincent M Mellnick, Sanjeev Bhalla, Meghan G Lubner, Perry J Pickhardt, Christine O Menias
Invasive fungal and fungal-like infections contribute to substantial morbidity and mortality in immunocompromised individuals. The incidence of these infections is increasing-largely because of rising numbers of immunocompromised patients, including those with neutropenia, human immunodeficiency virus, chronic immunosuppression, indwelling prostheses, burns, and diabetes mellitus, and those taking broad-spectrum antibiotics. Invasive fungal pathogens include primary mycotic organisms such as Histoplasma capsulatum, Coccidioides immitis, Blastomyces dermatitidis, and Paracoccidioides brasiliensis, which are true pathogens and inherently virulent...
July 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28616054/an-investigation-on-non-invasive-fungal-sinusitis-molecular-identification-of-etiologic-agents
#10
Abdolrasoul Mohammadi, Seyed Mostafa Hashemi, Sayed Hamidreza Abtahi, Seyed Mohammad Lajevardi, Sahar Kianipour, Rasoul Mohammadi
BACKGROUND: Fungal sinusitis is increasing worldwide in the past two decades. It is divided into two types including invasive and noninvasive. Noninvasive types contain allergic fungal sinusitis (AFS) and fungus ball. AFS is a hypersensitivity reaction to fungal allergens in the mucosa of the sinonasal tract in atopic individuals. The fungus ball is a different type of noninvasive fungal rhinosinusitis which is delineated as an accumulation of debris and fungal elements inside a paranasal sinus...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/28586604/orbital-involvement-in-sinonasal-diseases
#11
Zia-Us-Salam Qazi, Sarfraz Latif, Sadia Maqsood Awan
BACKGROUND: Orbital involvement in sinonasal diseases can present as proptosis, ophthalmoplegia or even as blindness due to optic nerve damage. There are a number of sinonasal diseases which can involve eyes. The purpose of this study was to enlist diagnoses of all the patients with sinonasal disease, in which orbit was also involved unilaterally or bilaterally and to analyse the management strategy and final outcome in all the cases. METHODS: Hundred consecutive patients having orbital symptoms along with sinonasal complaints that presented in ENT department of Shaikh Zayed federal postgraduate medical institute were included in our prospective study...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28512505/chronic-invasive-fungal-sinusitis-presenting-as-inferior-altitudinal-visual-field-defect
#12
Reema Bansal, Aastha Takkar, Vivek Lal, Amanjit Bal, Sandeep Bansal
A young male with acute blurring of vision (6/9) complained of an inferior altitudinal field defect in right eye. Clinical ophthalmological examination was normal. Magnetic resonance imaging (MRI) of the brain revealed the expansion and mucosal thickening of right posterior ethmoid and sphenoid sinuses and opacified right maxillary sinus. Surgical intervention (transethmoidal sphenoidotomy) and histopathological examination revealed chronic invasive granulomatous fungal sinusitis. Anti-fungal therapy led to resolution of visual complaints and restoration of visual field defects...
June 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/28505035/invasive-fungal-sinusitis-treatment-of-the-orbit
#13
Evan Kalin-Hajdu, Kristin E Hirabayashi, M Reza Vagefi, Robert C Kersten
PURPOSE OF REVIEW: To summarize diagnostic techniques for invasive fungal rhinosinusitis and provide a review of treatment options once disease has spread to the orbit. RECENT FINDINGS: Improved imaging criteria, polymerase chain reaction and other serologic tests show promise in advancing our ability to accurately diagnose invasive fungal disease. Currently, there exists three treatment options for infected orbital tissue: exenteration, conservative debridement and transcutaneous retrobulbar injection of amphotericin B...
May 12, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28484525/invasive-aspergillus-sinusitis-with-orbitocranial-extension
#14
Saleh S Baeesa, Rakan F Bokhari, Khalid B Alghamdi, Hisham B Alem, Jaudah A Al-Maghrabi, Tariq A Madani
CONTEXT: Invasive sinonasal aspergillosis is a silently progressive disease that, left untreated, may invade the adjacent intracranial and intra-orbital compartments incurring serious morbidity. AIM: To evaluate our results of a collaborative surgical management plans for patients with invasive sinonasal aspergillosis with orbitocranial extension. SETTING AND DESIGN: Retrospective study. MATERIALS AND METHODS: Between the years 2000 and 2012, 12 patients with Aspergillus sinusitis with orbitocranial extension were treated at our institution...
April 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28452707/complete-surgical-resection-and-short-term-survival-in-acute-invasive-fungal-rhinosinusitis
#15
Christopher R Roxbury, David F Smith, Thomas S Higgins, Stella E Lee, Gary L Gallia, Masaru Ishii, Andrew P Lane, Douglas D Reh
BACKGROUND: Acute invasive fungal rhinosinusitis (AIFR) is a fulminant fungal infection seen in patients who are immunocompromised. Due to its rarity, there is little evidence regarding the appropriate antifungal treatment regimen, especially the degree of surgical intervention. OBJECTIVE: To assess factors that impact short-term survival in AIFR as defined by survival to hospital discharge and to develop a staging system to predict survival and complete surgical resection...
March 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28438285/fungal-rhinosinusitis-a-radiological-review-with-intraoperative-correlation
#16
REVIEW
Elaine Ni Mhurchu, Javier Ospina, Arif S Janjua, Jason R Shewchuk, Alexandra T Vertinsky
The interaction between fungi and the sinonasal tract results in a range of clinical presentations with a broad spectrum of clinical severity. The most commonly accepted classification system divides fungal rhinosinusitis into invasive and noninvasive subtypes based on histopathological evidence of tissue invasion by fungi. Invasive fungal rhinosinusitis is subdivided into acute invasive and chronic invasive categories. The chronic invasive category includes a subcategory of chronic granulomatous disease. Noninvasive fungal disease includes localized fungal colonization, fungal ball, and allergic fungal rhinosinusitis...
May 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28429616/advanced-surgical-technique-for-invasive-fungal-sinusitis-endoscopic-orbit-sinus-combined-approach
#17
Kunihiro Nishimura, Yasuhiro Takahashi, Yuka Yamagishi, Shinya Banno, Yasue Uchida, Tohru Tanigawa, Munekazu Naito, Hirohiko Kakizaki, Hiromi Ueda, Tetsuya Ogawa
BACKGROUND: Invasive fungal sinusitis is usually associated with poor prognosis, but no clear guidelines have been established for surgical treatment. Here, we report the development and application of the endoscopic orbit-sinus combined approach (EOSCA), a novel surgical technique to approach the nasal cavity and orbit concurrently, in patients with invasive fungal sinusitis with orbital infiltration. MATERIAL AND METHODS: Two patients with invasive fungal sinusitis infiltrating the orbit underwent EOSCA...
April 21, 2017: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/28349786/the-use-of-frozen-section-in-the-early-diagnosis-of-acute-invasive-fungal-sinusitis
#18
C Claire Melancon, John D Clinger
Objectives Acute invasive fungal sinusitis (AIFS) remains a significant cause of morbidity and mortality in the immunocompromised patient population. Early diagnosis is key to improving patient outcomes. Frozen section biopsies have been shown to decrease time to diagnosis when compared with permanent pathology. However, its accuracy has not been adequately described in the literature, specifically in regard to AIFS. The aim of this study is to evaluate the statistical diagnostic accuracy of frozen sections and to review the etiology, clinical presentation, and current diagnostic protocols in management of AIFS...
March 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28341385/imaging-of-intracranial-and-orbital-complications-of-sinusitis-and-atypical-sinus-infection-what-the-radiologist-needs-to-know
#19
REVIEW
Vinodkumar Velayudhan, Zeshan A Chaudhry, Wendy R K Smoker, Roman Shinder, Deborah L Reede
Sinusitis is a common disease. Complications, however, are less common and can be life threatening. Major complications occur from extension of disease into the orbit and intracranial compartment and often require emergent treatment with intravenous (IV) antibiotics or operative intervention. Immunocompromised patients with acute sinusitis are susceptible to atypical infections, such as invasive fungal sinusitis, which is a surgical emergency. Therefore, it is important to accurately and promptly identify potentional complications of acute sinusitis to ensure appropriate treatment and minimize negative outcomes...
January 18, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28336168/-pseudo-tumoral-invasive-fungus-infection-of-the-maxillary-sinus-in-abidjan
#20
A K Tanon, C Assouan, E Anzouan-Kacou, D N'guessan, A Salami, S Boni, E Konan
INTRODUCTION: The invasive fungal infection of the maxillary sinus is a rare and serious disease generally favored by immunosuppression. We report an exceptional case of pseudotumoral invasive fungal infection of the maxillary sinus in an immunocompetent patient. OBSERVATION: A 32-year-old patient consulted for labial and left temporal swelling associated with proptosis and chemosis that has been developing for 18 months. The scanner objectified a filling of the left maxillary sinus, and the ipsilateral orbital cavity, and the surrounding muscles...
March 20, 2017: Journal de Mycologie Médicale
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