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Cancer survivor fertility

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https://www.readbyqxmd.com/read/29785559/childbirth-after-adolescent-and-young-adult-cancer-a-population-based-study
#1
Hazel B Nichols, Chelsea Anderson, Kathryn J Ruddy, Kristin Z Black, Barbara Luke, Stephanie M Engel, Jennifer E Mersereau
PURPOSE: Annually, > 45,000 US women are diagnosed with cancer during adolescence and young adulthood (AYA). Since 2006, national guidelines have recommended fertility counseling for cancer patients. We examined childbirth after AYA cancer by calendar period, cancer diagnosis, and maternal characteristics. METHODS: We identified a cohort of women with an incident invasive AYA cancer diagnosis at ages 15-39 during 2000-2013 in North Carolina. Cancer records were linked with statewide birth certificates through 2014...
May 22, 2018: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29782184/the-growth-of-preantral-follicles-and-the-impact-of-different-supplementations-and-circumstances-a-review-study-with-focus-on-bovine-and-human-preantral-follicles
#2
Zahra Rajabi, Zunair Khokhar, Hossein Yazdekhasti
One of the most important concerns cancer survivors face is fertility. Current treatment modalities often result in damage to the reproductive system. Different options have been proposed to preserve the fertility of affected women, and many attempts have been made to improve their chance of childbearing after therapy. Cryopreservation of ovarian tissue and follicles before the onset of cancer treatment and then either transplantation of ovarian tissue or culture of ovarian tissue and individual follicles in vitro is a commonly cited approach...
May 21, 2018: Cellular Reprogramming
https://www.readbyqxmd.com/read/29774444/male-fertility-preservation
#3
REVIEW
J Abram McBride, Larry I Lipshultz
PURPOSE OF REVIEW: With improvements in cancer treatment outcomes and an increase in cancer survivorship, understanding the importance of fertility preservation options prior to undergoing cancer treatment is essential. Therefore, we review herein the effect of cancer and its treatment on male fertility, the rationale for sperm cryopreservation, options for sperm retrieval, ART outcomes, and experimental options. RECENT FINDINGS: Recent data update fertility outcomes with newer cancer therapies and provide longitudinal insight into survivor paternity with and without fertility preservation...
May 17, 2018: Current Urology Reports
https://www.readbyqxmd.com/read/29754073/fertility-preservation-and-cancer-how-many-persons-are-concerned
#4
Christine Le Bihan-Benjamin, Natalie Hoog-Labouret, Delphine Lefeuvre, Frédérique Carré-Pigeon, Philippe Jean Bousquet
OBJECTIVE: A significant proportion of cancer survivors experience chronic health sequelae, one of them being fertility impairment. However, even if many reports, guidelines and positions papers focus on fertility preservation and its needs, access to fertility preservation is not currently offered to all the patients concerned, and the targeted population is not well counted. STUDY DESIGN: A cross sectional study was conducted using the French cancer cohort, a cohort covering the whole French population and including around 7 million of cancer patients...
May 8, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29721475/practical-consensus-recommendations-on-fertility-preservation-in-patients-with-breast-cancer
#5
Jyoti Bajpai, A Majumdar, R Satwik, N Rohatgi, V Jain, D Gupta, R Agarwal, S Mittal, S K Verma, P M Parikh, S Aggarwal
Young women diagnosed with cancer today have a greater chance of long-term survival than ever before. Successful survivorship for this group of patients includes maintaining a high quality of life after a cancer diagnosis and treatment; however, lifesaving treatments such as chemotherapy, radiation, and surgery can impact survivors by impairing reproductive and endocrine health. Expert oncologists along with reproductive medicine specialists discuss fertility preservation options in this chapter since fertility preservation is becoming a priority for young women with breast cancer...
April 2018: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/29715049/pregnancy-achieved-using-donor-eggs-in-cancer-survivors-with-treatment-induced-ovarian-failure-obstetric-and-perinatal-outcome
#6
Anna Marklund, Josefine Nasiell, Ann-Sofie Berger, Antonia Fagerberg, Kenny A Rodriguez-Wallberg
BACKGROUND: Egg donation is a common fertility treatment in female cancer survivors with reproductive wish and iatrogenic ovarian failure. We examined whether women previously treated for cancer have a higher risk of pregnancy complications after egg donation treatments when compared to women without cancer history. METHODS: In this prospective cohort treated during 2003-2015 at a single center, 31 women with previous history of cancer achieved 25 deliveries and 212 women without cancer history achieved 244 deliveries...
May 1, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29704433/retrievable-hydrogels-for-ovarian-follicle-transplantation-and-oocyte-collection
#7
Peter D Rios, Ekaterina Kniazeva, Hoi Chang Lee, Shuo Xiao, Robert S Oakes, Eiji Saito, Jacqueline S Jeruss, Ariella Shikanov, Teresa K Woodruff, Lonnie D Shea
Cancer survivorship rates have drastically increased due to improved efficacy of oncologic treatments. Consequently, clinical concerns have shifted from solely focusing on survival to quality of life, with fertility preservation as an important consideration. Among fertility preservation strategies for female patients, ovarian tissue cryopreservation and subsequent re-implantation has been the only clinical option available to cancer survivors with cryopreserved tissue. However, follicle atresia post-transplantation and risk of re-introducing malignant cells have prevented this procedure from becoming widely adopted in clinics...
April 28, 2018: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/29674220/childbearing-across-borders-fertility-and-parenthood-attitudes-and-decisions-among-breast-cancer-survivors-in-usa-and-portugal
#8
Vânia Gonçalves, Janella Hudson, Maria Cristina Canavarro, Julie Morris, M Catherine Lee, Kristine A Donovan, Steven K Sutton, Susan T Vadaparampil, Gwendolyn P Quinn
OBJECTIVE: To compare fertility and childbearing attitudes and decisions of Portuguese and American female reproductive aged breast cancer survivors. METHODS: This was a cross-sectional study of 102 young breast cancer survivors (59 from Portugal and 43 from USA). Demographic, clinical and reproductive information were collected. Fertility and parenthood attitudes and decisions were assessed through a self-report questionnaire devised specifically for the study...
April 16, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29672191/knowledge-and-beliefs-about-oncofertility-and-associations-with-quality-of-life-among-adolescent-and-young-adult-survivors-of-pediatric-cancer
#9
Andrea C Johnson, Darren Mays, Kathryn Rehberg, Aziza Shad, Kenneth P Tercyak
PURPOSE: Adolescent and young adult (AYA) cancer survivors experience fertility and childrearing challenges in adulthood, but there is limited evidence on awareness, beliefs, and concerns about oncofertility in this population, needs for supportive resources, and associations with quality of life (QoL). METHODS: Participants were 69 AYAs aged 12-25 who were diagnosed with cancer at age 18 years or younger and ≥1 year cancer free, recruited from childhood cancer clinical records and support organizations...
April 19, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29671528/testicular-cancer-diagnosis-and-treatment
#10
Drew C Baird, Garrett J Meyers, Jocelyn S Hu
Testicular cancer is the most common solid tumor among males 15 to 34 years of age, with an estimated 8,850 new cases and 410 deaths during 2017 in the United States. With effective treatment, the overall five-year survival rate is 97%. Risk factors for testicular cancer include undescended testis (cryptorchidism), personal or family history of testicular cancer, age, ethnicity, and infertility. The U.S. Preventive Services Task Force recommends against routine screening in asymptomatic men. Men with symptoms should receive a complete history and physical examination...
February 15, 2018: American Family Physician
https://www.readbyqxmd.com/read/29660436/in-vitro-study-of-doxorubicin-induced-oxidative-stress-in-spermatogonia-and-immature-sertoli-cells
#11
Amélie R Tremblay, Geraldine Delbes
Pediatric chemotherapy treatments can impair long-term male fertility. Unfortunately, no fertility preservation solution is available for pre-pubertal boys. Studies suggest that doxorubicin, used against pediatric cancers, induces oxidative stress in the testis. However, the targeted testicular cell types remain unknown. The goal of this study was to determine whether doxorubicin can induce oxidative stress in rat spermatogonia (GC-6Spg) and immature Sertoli (Ser-W3) cell lines, and to assess their protection by antioxidants...
April 13, 2018: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29617794/reproductive-intentions-and-use-of-reproductive-health-care-among-female-survivors-of-childhood-cancer
#12
M van Dijk, M H van den Berg, A Overbeek, C B Lambalk, M M van den Heuvel-Eibrink, W J Tissing, L C Kremer, H J van der Pal, J J Loonen, B Versluys, D Bresters, G J L Kaspers, F E van Leeuwen, E van Dulmen-den Broeder
STUDY QUESTION: Do female childhood cancer survivors (CCSs) express a decreased desire to have children and do they use reproductive health care more often compared to women without a history of cancer? SUMMARY ANSWER: Overall, no difference was found in the desire to have children between CCSs and controls, whereas CCSs consult a fertility specialist more often, at a younger age, and sooner after their first attempt at conceiving. WHAT IS KNOWN ALREADY: Female CCSs may face a shorter than anticipated reproductive window as a result of their cancer treatment...
March 30, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29588102/women-treated-for-gynaecological-cancer-during-young-adulthood-a-mixed-methods-study-of-perceived-psychological-distress-and-experiences-of-support-from-health-care-following-end-of-treatment
#13
Elisabet Mattsson, Kim Einhorn, Lisa Ljungman, Inger Sundström-Poromaa, Karin Stålberg, Anna Wikman
OBJECTIVE: To investigate the prevalence and predictors of cancer-related distress in younger women treated for gynaecological cancer, and to explore women's needs and experiences of psychosocial support following end-of-treatment. METHODS: Data were collected from 337 gynaecological cancer survivors, 19-39years at diagnosis, using a study-specific questionnaire and the Swedish Quality Register of Gynaecologic Cancer. Predictors of distress were investigated with multivariable logistic regression analysis...
March 24, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29537742/-fertility-and-cancer-in-young-adults-cured-but-what-about-having-children
#14
Marie-Estelle Gaignard, Julie Bénard, Noémie Lang
Every year, cancer affects more than a million adolescents and young adults (AYA) in high-income countries. AYA patients represent a heterogeneous but distinct population, aged from 15 to 39 (-45) years old, among which different types of cancer are found compared to the ones affecting children and older adults. Although these pathologies remain the leading cause of death in the AYA age range, the survival rate in this population has significantly improved in recent years, averaging 85%. The aim of this article is to review one major issue in AYA survivors, which is the risk of impaired fertility due to oncological treatments, and the different strategies available to address this problem...
March 14, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29537134/fertility-perspectives-and-priorities-among-male-adolescents-and-young-adults-in-cancer-survivorship
#15
Leena Nahata, Nicole M Caltabellotta, Nicholas D Yeager, Vicky Lehmann, Stacy L Whiteside, Sarah H O'Brien, Gwendolyn P Quinn, Cynthia A Gerhardt
Infertility is a common and distressing late effect of cancer treatment among male survivors. Investigators examined desire for parenthood, prioritization of fertility compared to other life goals, and reports of fertility-related discussions among a cohort of male adolescent and young adult survivors. Eighty percent desired a biological child, yet only 31% ranked having a child among their "top 3" life goals. Only 40% reported fertility-related discussions with their health care providers in survivorship...
March 14, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29528188/challenges-in-fertility-preservation-among-male-adolescent-and-young-adult-cancer-survivors
#16
Esther L Finney, Emilie K Johnson
No abstract text is available yet for this article.
March 12, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29508213/sexual-function-in-adolescent-and-young-adult-cancer-survivors-a-population-based-study
#17
Maria Olsson, Gunnar Steineck, Karin Enskär, Ulrica Wilderäng, Marianne Jarfelt
PURPOSE: Previous research has established that treatments for cancer can result in short- and long-term effects on sexual function in adult cancer patients. The purpose was to investigate patient-reported physical and psychosexual complications in adolescents and young adults after they have undergone treatment for cancer. METHODS: In this population-based study, a study-specific questionnaire was developed by a method used in several previous investigations carried out by our research group, Clinical Cancer Epidemiology...
March 5, 2018: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29493127/options-for-fertility-preservation-in-children
#18
Asma Javed, Zaraq Khan, Siobhan T Pittock, Jani R Jensen
Fertility preservation therapies can conserve future reproductive potential for persons facing serious medical diagnoses. With cure rates for childhood cancer reaching almost 80%, quality-of-life concerns for long-term survivors, including future parenting, are becoming more pertinent. Late effects of childhood cancer can be divided into physical, social, psychological, and spiritual domains. Potential loss of fertility threatens the well-being of these children in all these domains. Providers often hesitate to discuss fertility preservation with the patients...
March 2018: Pediatric Endocrinology Reviews: PER
https://www.readbyqxmd.com/read/29466084/fertility-related-perceptions-and-impact-on-romantic-relationships-among-adult-survivors-of-childhood-cancer
#19
Vicky Lehmann, Leena Nahata, Amanda C Ferrante, Jennifer A Hansen-Moore, Nicholas D Yeager, James L Klosky, Cynthia A Gerhardt
PURPOSE: To present an overview of fertility-related perceptions and describe the perceived negative/positive impact of (potential) infertility on romantic relationships among childhood cancer survivors. METHODS: Male and female long-term childhood cancer survivors (N = 92) aged 22-43 and 7-37 years postdiagnosis, completed an online survey about fertility-related perceptions (i.e., knowledge, beliefs, uncertainty, concern, and attitudes toward testing) and romantic relationships...
February 21, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29461592/health-related-quality-of-life-and-psychosocial-implications-in-testicular-cancer-survivors-a-literature-review
#20
F Cappuccio, S Rossetti, C Cavaliere, G Iovane, R Taibi, C D'Aniello, C Imbimbo, S Facchini, V Abate, D Barberio, G Facchini
OBJECTIVE: In this review, we focused our attention on Quality of Life (QoL) of testicular cancer survivors (TCSs), in general and in the most relevant areas. Several key findings have been highlighted in our review. MATERIALS AND METHODS: PubMed, MEDLINE and PsycINFO databases were consulted to find published studies, from 1980 to May 2017, that met our inclusion criteria. RESULTS: The majority of studies investigated older adult TCSs, while few studies on adolescent and young adult patients were available...
February 2018: European Review for Medical and Pharmacological Sciences
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