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https://www.readbyqxmd.com/read/27910808/magnesium-and-depression
#1
Anna Serefko, Aleksandra Szopa, Ewa Poleszak
Magnesium is one of the most important elements in the human body and is involved in a number of biochemical processes crucial for the proper functioning of the cardiovascular, alimentary, endocrine, and osteoarticular systems. It also plays a vital modulatory role in brain biochemistry, influencing several neurotransmission pathways associated with the development of depression. Personality changes, including apathy, depression, agitation, confusion, anxiety, and delirium are observed when there is a deficiency of this element...
March 1, 2016: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/27910201/meal-insulin-cycle-a-visual-summary-of-the-biochemical-events-between-meals
#2
Stavros Kalogiannis
In the present article, a scheme that summarizes the biochemical events occurring in the human body after the consumption of a meal is proposed. The scheme illustrates the metabolic sequence as a series of counteracting components occupying opposite positions in a cycle, indicating their opposite actions or physiological states, such as meal versus energy consumption, increase versus decrease of blood glucose levels, and excretion of insulin versus excretion of glucagon. Furthermore, the cycle is complemented by a table indicating the acceleration or inhibition of selected metabolic pathways and actions...
December 2, 2016: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/27892861/effects-of-myxoma-virus-and-rabbit-hemorrhagic-disease-virus-on-the-physiological-condition-of-wild-european-rabbits-is-blood-biochemistry-a-useful-monitoring-tool
#3
Isabel Pacios-Palma, Simone Santoro, Alejandro Bertó-Moran, Sacramento Moreno, Carlos Rouco
Myxomatosis and rabbit hemorrhagic disease (RHD) are the major viral diseases that affect the wild European rabbit (Oryctolagus cuniculus). These diseases arrived in Europe within the last decades and have caused wild rabbit populations to decline dramatically. Both viruses are currently considered to be endemic in the Iberian Peninsula; periodic outbreaks that strongly impact wild populations regularly occur. Myxoma virus (MV) and rabbit hemorrhagic disease virus (RHDV) alter the physiology of infected rabbits, resulting in physical deterioration...
October 1, 2016: Research in Veterinary Science
https://www.readbyqxmd.com/read/27885226/association-between-the-nutritional-status-and-the-severity-of-sarcopenia-among-community-dwelling-elderly-japanese-people
#4
Satsuki Komai, Yutaka Watanabe, Yoshinori Fujiwara, Hunkyung Kim, Ayako Edahiro, Hisashi Kawai, Hideyo Yoshida, Shuichi Obuchi, Yayoi Tanaka, Hirohiko Hirano
AIM: To investigate the association between nutritional evaluation indices (body mass index, albumin, and weight loss) and sarcopenia severity among community-dwelling elderly people in Japan. METHODS: The subjects consisted of 758 community-dwelling elderly people ≥65 years of age, categorized into two groups by based on Operation of long life medical care system (medical care system for elderly in the latter stage of life), the cut-off value for age used was 75...
2016: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/27881988/identification-of-a-solanum-pennellii-chromosome-4-fruit-flavor-and-nutritional-quality-associated-metabolite-qtl
#5
Zhongyuan Liu, Saleh Alseekh, Yariv Brotman, Yi Zheng, Zhangjun Fei, Denise M Tieman, James J Giovannoni, Alisdair R Fernie, Harry J Klee
A major resource for tomato quality improvement and gene discovery is the collection of introgression lines (ILs) of cultivated Solanum lycopersicum that contain different, defined chromosomal segments derived from the wild tomato relative, S. pennellii. Among these lines, IL4-4, in which the bottom of S. lycopersicum (cv. M82) chromosome 4 is replaced by the corresponding S. pennellii segment, is altered in many primary and secondary metabolites, including many related to fruit flavor and nutritional quality...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27843571/cachexia-in-cancer-what-is-in-the-definition
#6
Greetje Vanhoutte, Mick van de Wiel, Kristin Wouters, Michaël Sels, Linda Bartolomeeussen, Sven De Keersmaecker, Caroline Verschueren, Veronique De Vroey, Annemieke De Wilde, Elke Smits, Kin Jip Cheung, Liesbeth De Clerck, Petra Aerts, Didier Baert, Caroline Vandoninck, Sofie Kindt, Sofie Schelfhaut, Marc Vankerkhoven, Annelies Troch, Lore Ceulemans, Hanne Vandenbergh, Sven Leys, Tim Rondou, Elke Dewitte, Kristel Maes, Patrick Pauwels, Benedicte De Winter, Luc Van Gaal, Dirk Ysebaert, Marc Peeters
OBJECTIVE: This study aimed to provide evidence-based results on differences in overall survival (OS) rate to guide the diagnosis of cancer cachexia. DESIGN: Data collection and clinical assessment was performed every 3 months (5 visits): baseline data, muscle strength, nutritional and psychosocial status. 2 definitions on cachexia using different diagnostic criteria were applied for the same patient population. Fearon et al's definition is based on weight loss, body mass index (BMI) and sarcopenia...
2016: BMJ Open Gastroenterology
https://www.readbyqxmd.com/read/27793524/use-of-routinely-available-clinical-nutritional-and-functional-criteria-to-classify-cachexia-in-advanced-cancer-patients
#7
Antonio A L Vigano, José A Morais, Lorella Ciutto, Leonard Rosenthall, Jonathan di Tomasso, Sarah Khan, Henry Olders, Manuel Borod, Robert D Kilgour
BACKGROUND: Cachexia is a highly prevalent syndrome in cancer and chronic diseases. However, due to the heterogeneous features of cancer cachexia, its identification and classification challenge clinical practitioners. OBJECTIVE: To determine the clinical relevance of a cancer cachexia classification system in advanced cancer patients. DESIGN: Beginning with the four-stage classification system proposed for cachexia [non-cachexia (NCa), pre-cachexia (PCa), cachexia (Ca) and refractory cachexia (RCa)], we assigned patients to these cachexia stages according to five classification criteria available in clinical practice: 1) biochemistry (high C-reactive protein or leukocytes, or hypoalbuminemia, or anemia), 2) food intake (normal/decreased), weight loss: 3) moderate (≤5%) or 4) significant (>5%/past six months) and 5) performance status (Eastern Cooperative Oncology Group Performance Status ≥ 3)...
September 20, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27756558/safety-assessment-of-widely-used-fermented-virgin-coconut-oil-cocos-nucifera-in-malaysia-chronic-toxicity-studies-and-sar-analysis-of-the-active-components
#8
Ahmad H Ibrahim, Md Shamsuddin Sultan Khan, Sawsan S Al-Rawi, Mohamed B Khadeer Ahamed, Aman Shah Bin Abdul Majid, Fouad Saleih R Al-Suede, Dan Ji, Amin Malik Shah Abdul Majid
Fermented Virgin Coconut Oil (FVCO) is widely used in the Southeast Asia as food and traditional medicine. The objective of the present study is the evaluation of chronic safety of the commercialized FVCO of Malaysia and other Southeast Asian countries. A single dose of 5000 mg/kg of FVCO was administered orally in rats (each group, n = 5) for the acute toxicity study and 175, 550 and 2000 mg/kg for sub-chronic and chronic studies (each group, n = 10), respectively. The behavior, mortality, and body weight of the rats were assessed to determine the toxic effects of FVCO...
November 2016: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/27751199/a-comparison-between-different-concentrations-and-sources-of-cobalt-in-goat-kid-nutrition
#9
A H Dezfoulian, H Aliarabi
There have been extensive studies in sheep and cattle considering cobalt (Co) supplementation and its effects on vitamin B12 concentrations in the body. However, there are limited studies on goats. The aim of this study was to compare two different sources of Co (sulfate v. glucoheptonate) at two different concentrations (0.25 and 0.5 mg/kg dry matter) in goat kid nutrition, and to evaluate the effects of these supplements on performance, serum vitamin B12, blood biochemistry and rumen volatile fatty acids...
October 18, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/27723384/physiologic-biomarkers-and-hendra-virus-infection-in-australian-black-flying-foxes-pteropus-alecto
#10
Lee McMichael, Daniel Edson, David Mayer, Alice Broos, Steven Kopp, Joanne Meers, Hume Field
Bats of the genus Pteropus (Pteropodidae), colloquially known as flying foxes, are recognized as the natural reservoir of Hendra virus, a zoonotic paramyxovirus responsible for mortality in horses and humans. Some previous studies have suggested that physiologic and ecologic factors promote Hendra virus infection in flying foxes, and by extension, spillover to horses and humans. However, the impact of Hendra virus infection on relevant physiologic biomarkers in flying foxes has not been measured. Over 12 mo in eastern Australia, we captured and sampled 446 individual black flying foxes ( Pteropus alecto ), a putative primary reservoir host species, and measured a suite of hematologic, plasma biochemistry, and urinary biomarkers...
October 10, 2016: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/27705753/leptin-levels-seasonality-and-thermal-acclimation-in-the-microbiotherid-marsupial-dromiciops-gliroides-does-photoperiod-play-a-role
#11
Marcela Franco, Carolina Contreras, Ned J Place, Francisco Bozinovic, Roberto F Nespolo
Mammals of the Neotropics are characterized by a marked annual cycle of activity, which is accompanied by several physiological changes at the levels of the whole organism, organs and tissues. The physiological characterization of these cycles is important, as it gives insight on the mechanisms by which animals adjust adaptively to seasonality. Here we studied the seasonal changes in blood biochemical parameters in the relict South American marsupial Dromiciops gliroides ("monito del monte" or "little mountain monkey"), under semi-natural conditions...
October 2, 2016: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/27702716/enteral-nutrition-preference-in-critical-care-fibre-enriched-or-fibre-free
#12
Hatice Yagmurdur, Figen Leblebici
BACKGROUND AND OBJECTIVES: This study's main aim was to observe the effects of a fibre-enriched nutrition solution on requisite feeding volume, which is directly proportional to energy intake in mechanically ventilated patients with enteral nutrition. METHODS AND STUDY DESIGN: Some 120 patients who required mechanical ventilation and enteral nutrition with a nasogastric tube were studied. Upon ICU admission, the patient's age, gender, weight, height, comorbidities, diagnosis and APACHE II score were recorded...
December 2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27666762/a-global-multicenter-study-on-reference-values-2-exploration-of-sources-of-variation-across-the-countries
#13
Kiyoshi Ichihara, Yesim Ozarda, Julian H Barth, George Klee, Yoshihisa Shimizu, Liangyu Xia, Mariza Hoffmann, Swarup Shah, Tandi Matsha, Janette Wassung, Francois Smit, Anna Ruzhanskaya, Joely Straseski, Daniel N Bustos, Shogo Kimura, Aki Takahashi
OBJECTIVES: The intent of this study, based on a global multicenter study of reference values (RVs) for serum analytes was to explore biological sources of variation (SVs) of the RVs among 12 countries around the world. METHODS: As described in the first part of this paper, RVs of 50 major serum analytes from 13,396 healthy individuals living in 12 countries were obtained. Analyzed in this study were 23 clinical chemistry analytes and 8 analytes measured by immunoturbidimetry...
September 22, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/27619544/daily-sesame-oil-supplementation-mitigates-ketoconazole-induced-oxidative-stress-mediated-apoptosis-and-hepatic-injury
#14
Srinivasan Periasamy, Chuan-Teng Liu, Se-Ping Chien, Ying-Chien Chen, Ming-Yie Liu
Ketoconazole (KCZ) is the most commonly used systemic antifungal drug. However, long-term treatment of KCZ induces hepatic injury. Oxidative stress is involved in KCZ-induced hepatic injury. Oxidative stress plays an important role in apoptosis-associated hepatic damage. Sesame oil is rich in potent antioxidants and antifungal constituents. It attenuates hepatic injury by inhibiting oxidative stress. Thus, sesame oil may protect against KCZ-induced oxidative stress, apoptosis and hepatic damage. The aim of the present study was to investigate the protective effect of sesame oil as a nutritional supplement on KCZ-induced hepatic injury in mice...
August 25, 2016: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/27599872/blood-type-biochemistry-and-human-disease
#15
REVIEW
D Rose Ewald, Susan C J Sumner
Associations between blood type and disease have been studied since the early 1900s when researchers determined that antibodies and antigens are inherited. In the 1950s, the chemical identification of the carbohydrate structure of surface antigens led to the understanding of biosynthetic pathways. The blood type is defined by oligosaccharide structures, which are specific to the antigens, thus, blood group antigens are secondary gene products, while the primary gene products are various glycosyltransferase enzymes that attach the sugar molecules to the oligosaccharide chain...
November 2016: Wiley Interdisciplinary Reviews. Systems Biology and Medicine
https://www.readbyqxmd.com/read/27547437/added-sugars-drive-nutrient-and-energy-deficit-in-obesity-a-new-paradigm
#16
REVIEW
James J DiNicolantonio, Amy Berger
Obesity has traditionally been thought of as a state of caloric imbalance, where the intake of calories exceeds the expenditure or 'burning' of calories. However, a more nuanced appreciation for the complex biochemistry and physiology of cellular energy generation suggests that obesity is a state of hormonal imbalance causing increased shunting of food energy into adipose tissue for storage, resulting in decreased satiety and ultimately leading to increased caloric intake. Adding to this hypothesis, we propose that obesity is also a state of nutrient and energy deficit, leading to decreased fatty acid mobilisation and oxidation, the result of which may be a natural disinclination towards physical activity...
2016: Open Heart
https://www.readbyqxmd.com/read/27545631/-nutritional-and-functional-assessment-of-peritoneal-dialysis-patients-in-the-clinical-practice-report-from-mito-dp-group
#17
Adamasco Cupisti, Claudia D'Alessandro, Gian Marco Caselli
Nutritional abnormalities and physical inactivity are risk factors of increased morbidity and mortality in patients with ESRD. Identify and define malnutrition, in particular protein-energy depletion (PEW), is an important task in the management of renal patients. The aim of this multicenter observational study was to implement the assessment of nutritional status and functional capacity in patients on peritoneal dialysis, including tests and validated methods which are relatively easy to apply in daily clinical practice...
July 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/27499393/nutritional-status-of-older-patients-with-oropharyngeal-dysphagia-in-a-chronic-versus-an-acute-clinical-situation
#18
Silvia Carrión, Maria Roca, Alicia Costa, Viridiana Arreola, Omar Ortega, Elisabet Palomera, Mateu Serra-Prat, Mateu Cabré, Pere Clavé
BACKGROUND: Oropharyngeal dysphagia (OD) is a prevalent risk factor for malnutrition (MN) in older patients and both conditions are related to poor outcome. OBJECTIVE: To explore the nutritional status in older patients with OD in a chronic and an acute clinical situation. DESIGN: We examined 95 older (≥70 years) patients with OD associated to chronic neurological diseases or aging, and 23 older patients with OD and acute community-acquired pneumonia (CAP) with videofluoroscopy; and 15 older people without OD...
July 26, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27485956/-conclusions-of-the-ii-international-and-iv-spanish-hydration-congress-toledo-spain-2nd-4th-december-2015
#19
Javier Aranceta-Bartrina, Ángel Gil, Ascensión Marcos, Carmen Pérez-Rodrigo, Lluis Serra-Majem, Gregorio Varela-Moreiras
Javier Aranceta-Bartrina1, Ángel Gil2, Ascensión Marcos3, Carmen Pérez-Rodrigo4, Lluis Serra-Majem5 and Gregorio Varela-Moreiras6*1Associate Professor at University of Navarra. Pamplona, Spain. 2Professor of Biochemistry and Molecular Biology. University of Granada. Granada, Spain. 3Research Professor at the Spanish National Research Council (CSIC). Madrid, Spain. 4President of Spanish Society of Community Nutrition (SENC). Bilbao, Spain. 5Professor of Preventive Medicine and Public Health. Director of Group of Nutrition...
2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/27477890/hypophosphataemia-and-parenteral-nutrition-biochemical-monitoring-incidence-and-outcomes
#20
En C Fung, Sasala R Wickramasinghe, Julia V Panteli, Martin A Crook
AIMS: The aim of this study was to assess the incidence and clinical associations of hypophosphataemia in patients undergoing parenteral nutrition (PN) and the importance of biochemical monitoring. METHODS: Patients (n = 57) on PN were identified from pharmacy and also dietician referral records. Access to patient case files and dietetics records provided details pertaining to diagnosis, indications for PN, the level of biochemistry monitoring, and any complications incurred...
August 1, 2016: British Journal of Biomedical Science
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