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Interrupted Time Series

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https://www.readbyqxmd.com/read/27923050/the-effect-of-alignment-changes-on-unilateral-transtibial-amputee-s-gait-a-systematic-review
#1
Niels Jonkergouw, Maarten R Prins, Arjan W P Buis, Peter van der Wurff
INTRODUCTION: Prosthetic alignment, positioning of a prosthetic foot relative to a socket, is an iterative process in which an amputee's gait is optimized through repetitive optical gait observation and induction of alignment adjustments when deviations are detected in spatiotemporal and kinematic gait parameters. An important limitation of the current prosthetic alignment approach is the subjectivity and the lack of standardized quantifiable baseline values. The purpose of this systematic review is to investigate if an optimal alignment criterion can be derived from published articles...
2016: PloS One
https://www.readbyqxmd.com/read/27920248/use-of-proton-pump-inhibitors-among-older-australians-national-quality-improvement-programmes-have-led-to-sustained-practice-change
#2
Nicole L Pratt, Lisa M Kalisch Ellett, Janet K Sluggett, Svetla V Gadzhanova, Emmae N Ramsay, Mhairi Kerr, Vanessa T LeBlanc, John D Barratt, Elizabeth E Roughead
OBJECTIVE: To evaluate the impact of national multifaceted initiatives to improve use of proton pump inhibitors (PPIs) on the use of PPIs among older Australians. DESIGN: Interrupted time series analysis using administrative health claims data from the Australian Government Department of Veterans' Affairs (DVA). SETTING: Australia. PARTICIPANTS: All veterans and dependents who received PPIs between January 2003 and December 2013...
December 4, 2016: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/27913372/an-ehealth-project-on-invasive-pneumococcal-disease-comprehensive-evaluation-of-a-promotional-campaign
#3
Donatella Panatto, Alexander Domnich, Roberto Gasparini, Paolo Bonanni, Giancarlo Icardi, Daniela Amicizia, Lucia Arata, Stefano Carozzo, Alessio Signori, Angela Bechini, Sara Boccalini
BACKGROUND: The recently launched Pneumo Rischio eHealth project, which consists of an app, a website, and social networking activity, is aimed at increasing public awareness of invasive pneumococcal disease (IPD). The launch of this project was prompted by the inadequate awareness of IPD among both laypeople and health care workers, the heavy socioeconomic burden of IPD, and the far from optimal vaccination coverage in Italy, despite the availability of safe and effective vaccines. OBJECTIVE: The objectives of our study were to analyze trends in Pneumo Rischio usage before and after a promotional campaign, to characterize its end users, and to assess its user-rated quality...
December 2, 2016: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/27911489/palliative-care-interventions-in-advanced-dementia
#4
REVIEW
Edel Murphy, Katherine Froggatt, Sheelah Connolly, Eamon O'Shea, Elizabeth L Sampson, Dympna Casey, Declan Devane
BACKGROUND: Dementia is a chronic, progressive and ultimately fatal neurodegenerative disease. Advanced dementia is characterised by profound cognitive impairment, inability to communicate verbally and complete functional dependence. Usual care of people with advanced dementia is not underpinned universally by a palliative approach. Palliative care has focused traditionally on care of people with cancer but for more than a decade, there have been increased calls worldwide to extend palliative care services to include all people with life-limiting illnesses in need of specialist care, including people with dementia...
December 2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27911487/external-inspection-of-compliance-with-standards-for-improved-healthcare-outcomes
#5
REVIEW
Gerd Flodgren, Daniela C Gonçalves-Bradley, Marie-Pascale Pomey
BACKGROUND: Inspection systems are used in healthcare to promote quality improvements (i.e. to achieve changes in organisational structures or processes, healthcare provider behaviour and patient outcomes). These systems are based on the assumption that externally promoted adherence to evidence-based standards (through inspection/assessment) will result in higher quality of healthcare. However, the benefits of external inspection in terms of organisational-, provider- and patient-level outcomes are not clear...
December 2, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27909040/association-between-organisational-and-workplace-cultures-and-patient-outcomes-systematic-review-protocol
#6
J Braithwaite, J Herkes, K Ludlow, G Lamprell, L Testa
INTRODUCTION: Despite widespread interest in the topic, no current synthesis of research is available analysing the linkages between organisational or workplace cultures on the one hand, and patient outcomes on the other. This protocol proposes a systematic review to analyse and synthesise the literature to date on this topic. The resulting review will discuss characteristics of included studies in terms of the type of healthcare settings researched, the measurements of organisational and workplace culture, patient outcomes measured and the influence of these cultures on patient outcomes...
December 1, 2016: BMJ Open
https://www.readbyqxmd.com/read/27899905/effects-of-individual-differences-in-working-memory-on-plan-presentational-choices
#7
Nava Tintarev, Judith Masthoff
This paper addresses research questions that are central to the area of visualization interfaces for decision support: (RQ1) whether individual user differences in working memory should be considered when choosing how to present visualizations; (RQ2) how to present the visualization to support effective decision making and processing; and (RQ3) how to evaluate the effectiveness of presentational choices. These questions are addressed in the context of presenting plans, or sequences of actions, to users. The experiments are conducted in several domains, and the findings are relevant to applications such as semi-autonomous systems in logistics...
2016: Frontiers in Psychology
https://www.readbyqxmd.com/read/27873322/non-medical-prescribing-versus-medical-prescribing-for-acute-and-chronic-disease-management-in-primary-and-secondary-care
#8
REVIEW
Greg Weeks, Johnson George, Katie Maclure, Derek Stewart
BACKGROUND: A range of health workforce strategies are needed to address health service demands in low-, middle- and high-income countries. Non-medical prescribing involves nurses, pharmacists, allied health professionals, and physician assistants substituting for doctors in a prescribing role, and this is one approach to improve access to medicines. OBJECTIVES: To assess clinical, patient-reported, and resource use outcomes of non-medical prescribing for managing acute and chronic health conditions in primary and secondary care settings compared with medical prescribing (usual care)...
November 22, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27871537/-1-8-million-and-counting-how-volatile-agent-education-has-decreased-our-spending-1000-per-day
#9
Scott A Miller, Carol A Aschenbrenner, Justin R Traunero, Loren A Bauman, Samuel S Lobell, Jeffrey S Kelly, John E Reynolds
STUDY OBJECTIVE: Volatile anesthetic agents comprise a substantial portion of every hospital's pharmacy budget. Challenged with an initiative to lower anesthetic drug expenditures, we developed an education-based intervention focused on reducing volatile anesthetic costs while preserving access to all available volatile anesthetics. When postintervention evaluation demonstrated a dramatic year-over-year reduction in volatile agent acquisition costs, we undertook a retrospective analysis of volatile anesthetic purchasing data using time series analysis to determine the impact of our educational initiative...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27868200/impact-of-copayment-changes-on-children-s-albuterol-inhaler-use-and-costs-after-the-clean-air-act-chlorofluorocarbon-ban
#10
Alison A Galbraith, Vicki Fung, Lingling Li, Melissa G Butler, James D Nordin, John Hsu, David Smith, William M Vollmer, Tracy A Lieu, Stephen B Soumerai, Ann Chen Wu
OBJECTIVE: To examine changes in children's albuterol use and out-of-pocket (OOP) costs in response to increased copayments after the Food and Drug Administration banned inhalers with chlorofluorocarbon (CFC) propellants. SETTING: Four health maintenance organizations (HMOs), two that increased copayments for albuterol inhalers that went from generic CFC-containing to branded CFC-free versions, and two that retained generic copayments for CFC-free inhalers (controls)...
November 20, 2016: Health Services Research
https://www.readbyqxmd.com/read/27865024/impact-of-the-zero-markup-drug-policy-on-hospitalization-expenditure-in-western-rural-china-an-interrupted-time-series-analysis
#11
Caijun Yang, Qian Shen, Wenfang Cai, Wenwen Zhu, Zongjie Li, Lina Wu, Yu Fang
OBJECTIVES: To assess the long-term effects of the introduction of China's zero markup drug policy on hospitalization expenditure and hospitalization expenditures after reimbursement. METHODS: An interrupted time series was used to evaluate the impact of the zero markup drug policy on hospitalization expenditure and hospitalization expenditure after reimbursement at primary health institutions in Fufeng County of Shaanxi Province, western China. Two regression models were developed...
November 16, 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27862597/impact-of-an-opioid-risk-reduction-initiative-on-motor-vehicle-crash-risk-among-chronic-opioid-therapy-patients
#12
Ryan N Hansen, Rod L Walker, Susan M Shortreed, Sascha Dublin, Kathleen Saunders, Evette J Ludman, Michael Von Korff
PURPOSE: Although prescription opioids have been associated with higher motor vehicle crash (MVC) risk, it is unknown whether health system initiatives to better manage chronic opioid therapy (COT) can reduce MVC risk at the population level. METHODS: We conducted an interrupted time series population-level cohort study at Group Health (GH), between January 2006 and September 2014, comparing MVC risk among COT patients who were GH members receiving care in either group practice or contracted care settings...
November 14, 2016: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/27861350/chlorhexidine-bathing-for-the-prevention-of-colonization-and-infection-with-multidrug-resistant-microorganisms-in-a-hematopoietic-stem-cell-transplantation-unit-over-a-9-year-period-impact-on-chlorhexidine-susceptibility
#13
Elisa Teixeira Mendes, Otavio T Ranzani, Ana Paula Marchi, Mariama Tomaz da Silva, José Ulysses Amigo Filho, Tânia Alves, Thais Guimarães, Anna S Levin, Silvia Figueiredo Costa
Health care associated infections (HAIs) are currently among the major challenges to the care of hematopoietic stem cell transplantation (HSCT) patients. The objective of the present study was to evaluate the impact of 2% chlorhexidine (CHG) bathing on the incidence of colonization and infection with vancomycin-resistant Enterococcus (VRE), multidrug-resistant (MDR) gram-negative pathogens, and to evaluate their CHG minimum inhibitory concentration (MIC) after the intervention.A quasi-experimental study with duration of 9 years was conducted...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27859873/impact-of-an-intervention-on-the-prescription-of-aliskiren-after-new-evidence-on-safety-reported
#14
Isabel Rosich Martí, Alejandro Allepuz, Gemma Rodriguez Palomar, Francesca Ortin Font, Maria Soler Cera
PURPOSE: The purpose of the study is to analyze the impact of an intervention to disseminate safety alerts on the utilization of Aliskiren added to angiotensin converting enzyme inhibitor (ACEI) or an angiotensin-receptor blocker (ARB). METHODS: Quasi-experimental design (non-randomized intervention) comparing the utilization of Aliskiren + ACEI or ARB in a primary care area-intervention (PCA-I) with a primary care area-control (PCA-C) following a safety alert...
November 16, 2016: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/27859370/how-user-fees-influence-contraception-in-low-and-middle-income-countries-a-systematic-review
#15
Catherine Korachais, Elodie Macouillard, Bruno Meessen
Accessible and quality reproductive health services are critical for low- and middle-income countries (LMICs). After a decade of waning investment in family planning, interest and funding are growing once again. This article assesses whether introducing, removing, or changing user fees for contraception has an effect on contraceptive use. We conducted a search of 14 international databases. We included randomized controlled trials, interrupted-time series analyses, controlled before-and-after study designs, and cohort studies that reported contraception-related variables as an outcome and a change in the price of contraceptives as an intervention...
November 17, 2016: Studies in Family Planning
https://www.readbyqxmd.com/read/27859338/family-planning-vouchers-in-low-and-middle-income-countries-a-systematic-review
#16
Ben Bellows, Carol Bulaya, Sophie Inambwae, Craig L Lissner, Moazzam Ali, Ashish Bajracharya
Family planning (FP) vouchers have targeted subsidies to disadvantaged populations for quality reproductive health services since the 1960s. To summarize the effect of FP voucher programs in low- and middle-income countries, a systematic review was conducted, screening studies from 33 databases through three phases: keyword search, title and abstract review, and full text review. Sixteen articles were selected including randomized control trials, controlled before-and-after, interrupted time series analyses, cohort, and before-and-after studies...
November 17, 2016: Studies in Family Planning
https://www.readbyqxmd.com/read/27856087/hemodialysis-hospitalizations-and-readmissions-the-effects-of-payment-reform
#17
Kevin F Erickson, Wolfgang C Winkelmayer, Glenn M Chertow, Jay Bhattacharya
BACKGROUND: In 2004, the Centers for Medicare & Medicaid Services changed reimbursement for physicians and advanced practitioners caring for patients receiving hemodialysis from a capitated to a tiered fee-for-service system, encouraging increased face-to-face visits. This early version of a pay-for-performance initiative targeted a care process: more frequent provider visits in hemodialysis. Although more frequent provider visits in hemodialysis are associated with fewer hospitalizations and rehospitalizations, it is unknown whether encouraging more frequent visits through reimbursement policy also yielded these benefits...
November 14, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27853954/spectral-domain-optical-coherence-tomography-findings-in-idiopathic-lamellar-macular-hole
#18
Elena Zampedri, Federica Romanelli, Francesco Semeraro, Barbara Parolini, Rino Frisina
BACKGROUND: To evaluate demographic, functional, and morphological parameters of idiopathic lamellar macular hole (ILMH). METHODS: Observational longitudinal retrospective study. Optical coherence tomography examinations and corresponding clinical charts of a series of consecutive patients affected by ILMH, between January 2010 and March 2015, from the database of the Department of Ophthalmology of Trento Hospital, Italy, have been collected and examined. Demographic and functional parameters were: age (year), gender (male/female), eye (right/left), lens status, best-corrected visual acuity (BCVA) in logarithm of the minimum angle of resolution (LogMAR)...
November 16, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27843420/historical-data-analysis-of-hospital-discharges-related-to-the-amerithrax-attack-in-florida
#19
Lauralyn K Burke, C Perry Brown, Tammie M Johnson
Interrupted time-series analysis (ITSA) can be used to identify, quantify, and evaluate the magnitude and direction of an event on the basis of time-series data. This study evaluates the impact of the bioterrorist anthrax attacks ("Amerithrax") on hospital inpatient discharges in the metropolitan statistical area of Palm Beach, Broward, and Miami-Dade counties in the fourth quarter of 2001. Three statistical methods-standardized incidence ratio (SIR), segmented regression, and an autoregressive integrated moving average (ARIMA)-were used to determine whether Amerithrax influenced inpatient utilization...
2016: Perspectives in Health Information Management
https://www.readbyqxmd.com/read/27836075/evaluation-of-the-implementation-and-effects-of-an-obstetric-kit-used-in-the-adamawa-region-of-cameroon
#20
Joachim Aimé Cacko, Kadari Cissé, Madeleine Wayack Pambè, Rachidatou Compaoré, Seni Kouanda
OBJECTIVE: To assess the implementation and effects of the strategy, introduced in June 2011, of making obstetric kits readily available in health facilities in the Adamaoua region of Cameroon. METHODS: We conducted a quasi-experimental study using an interrupted time series to assess the effects of the strategy, and a case study to evaluate its implementation. The reviewed data were gathered from 13 health facilities over a period from January 2008 to December 2014...
November 2016: International Journal of Gynaecology and Obstetrics
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