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Interrupted Time Series

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https://www.readbyqxmd.com/read/28339354/the-effects-of-an-educational-meeting-and-subsequent-computer-reminders-on-the-ordering-of-laboratory-tests-by-rheumatologists-an-interrupted-time-series-analysis
#1
Nienke Lesuis, Nathan den Broeder, Nadine Boers, Ester Piek, Steven Teerenstra, Marlies Hulscher, Ronald van Vollenhoven, Alfons A den Broeder
OBJECTIVES: To examine the effects of an educational meeting and subsequent computer reminders on the number of ordered laboratory tests. METHODS: Using interrupted time series analysis we assessed whether trends in the number of laboratory tests ordered by rheumatologists between September 2012 and September 2015 at the Sint Maartenskliniek (the Netherlands) changed following an educational meeting (September 2013) and the introduction of computer reminders into the Computerised Physician Order Entry System (July 2014)...
March 23, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28333762/impact-of-targeted-interventions-on-trends-in-central-line-associated-bloodstream-infection-a-single-center-experience-from-the-republic-of-korea
#2
Sun Young Cho, Doo Ryeon Chung, Jae Geum Ryu, Jong Rim Choi, Nayeon Ahn, Seonwoo Kim, Min-Ji Kim, Young Eun Ha, Cheol-In Kang, Kyong Ran Peck, Jae-Hoon Song
OBJECTIVE: To assess the impact of targeted interventions on trends in central line-associated bloodstream infection. DESIGN: A before-and-after study between January 2013 and September 2014. SETTING: Tertiary hospital in the Republic of Korea. PATIENTS: All patients with central-line catheters in the hospital. INTERVENTIONS: In September 2013, interventions that targeted central line insertion practices were implemented in 10 ICUs, including compliance monitoring with a central line insertion practices bundle and use of an all-inclusive catheter kit...
March 22, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28333302/outcomes-of-multisite-antimicrobial-stewardship-programme-implementation-with-a-shared-clinical-decision-support-system
#3
Stuart E Bond, Adriana J Chubaty, Suman Adhikari, Spiros Miyakis, Craig S Boutlis, Wilfred W Yeo, Marijka J Batterham, Cara Dickson, Brendan J McMullan, Mona Mostaghim, Samantha Li-Yan Hui, Kate R Clezy, Pamela Konecny
Background: Studies evaluating antimicrobial stewardship programmes (ASPs) supported by computerized clinical decision support systems (CDSSs) have predominantly been conducted in single site metropolitan hospitals. Objectives: To examine outcomes of multisite ASP implementation supported by a centrally deployed CDSS. Methods: An interrupted time series study was conducted across five hospitals in New South Wales, Australia, from 2010 to 2014...
March 14, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28333297/effect-of-adding-a-mobile-health-intervention-to-a-multimodal-antimicrobial-stewardship-programme-across-three-teaching-hospitals-an-interrupted-time-series-study
#4
E Charani, M Gharbi, L S P Moore, E Castro-Sanchéz, W Lawson, M Gilchrist, A H Holmes
Objectives: To evaluate the impact of adding a mobile health (mHealth) decision support system for antibiotic prescribing to an established antimicrobial stewardship programme (ASP). Methods: In August 2011, the antimicrobial prescribing policy was converted into a mobile application (app). A segmented regression analysis of interrupted time series was used to assess the impact of the app on prescribing indicators, using data (2008-14) from a biannual point prevalence survey of medical and surgical wards...
February 28, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28323460/supply-side-disruption-in-cocaine-production-associated-with-cocaine-related-maternal-and-child-health-outcomes-in-the-united-states
#5
Chris Delcher, Melvin Livingston, Yanning Wang, Meredith Mowitz, Mildred Maldonado-Molina, Bruce A Goldberger
OBJECTIVES: To investigate the effects of precursor chemical regulation aimed at reducing cocaine production on cocaine-related maternal and newborn hospital stays in the United States. METHODS: We analyzed monthly counts of maternal and neonatal stays from January 2002 through December 2013 by using a quasi-experimental interrupted time series design. We estimated the preregulation linear trend, postregulation change in linear trend, and abrupt change in level...
March 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28321553/enhanced-recovery-after-surgery-eras-%C3%A2-in-individuals-with-diabetes-a-systematic-review
#6
Zaina Albalawi, Michael Laffin, Leah Gramlich, Peter Senior, Finlay A McAlister
BACKGROUND: Prevalence of diabetes in surgical patients is 10-40%. It is well recognized that they have higher rates of complications, and longer stays in hospital compared to patients without diabetes. Enhanced recovery after surgery (ERAS) is an evidence-based multimodal surgical care pathway that improves postoperative complications and length of stay in patients without diabetes. This review evaluates the evidence on whether individuals with diabetes would benefit from ERAS implementation...
March 20, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28318769/impact-of-meningococcal-c-conjugate-vaccination-four-years-after-introduction-of-routine-childhood-immunization-in-brazil
#7
Ana Lucia Andrade, Ruth Minamisava, Lisia Moura Tomich, Ana Paula Lemos, Maria Cecilia Gorla, Maria Cristina de Cunto Brandileone, Carla Madga S Domingues, Camile de Moraes, Gabriela Policena, Ana Luiza Bierrenbach
BACKGROUND: Routine infant immunization with meningococcal C conjugate (MCC) vaccination started in Brazil in November 2010, scheduled at three and five months plus a booster at 12-15months of age. No catch-up was implemented. We assessed the impact of vaccination on meningococcal C disease (MenC) four years after vaccination start in the National Immunization Program. METHODS: We performed an ecological quasi-experimental design from 2008 to 2014 using a deterministic linkage between the National Notification and the National Reference Laboratory databases for meningitis...
March 15, 2017: Vaccine
https://www.readbyqxmd.com/read/28299592/the-effect-of-a-celebrity-health-disclosure-on-demand-for-health-care-trends-in-brca-testing-and-subsequent-health-services-use
#8
Megan C Roberts, Stacie B Dusetzina
In May 2013, an internationally renowned celebrity-Angelina Jolie-disclosed her receipt of BRCA1/BRCA2 (BRCA) testing and subsequent double mastectomy in a highly publicized editorial. Publicity surrounding celebrity health services use increases awareness of important health issues and demand for health services. We aimed to describe BRCA testing trends before and after Jolie's disclosure, breast cancer-related services use following testing, and test reimbursement trends. MarketScan Commercial Claims data were used to compare trends in BRCA testing before and after Jolie's health disclosure using an interrupted time series model among women aged 18-64...
March 15, 2017: Journal of Community Genetics
https://www.readbyqxmd.com/read/28293198/fetal-heart-rate-analysis-for-automatic-detection-of-perinatal-hypoxia-using-normalized-compression-distance-and-machine-learning
#9
Óscar Barquero-Pérez, Ricardo Santiago-Mozos, José M Lillo-Castellano, Beatriz García-Viruete, Rebeca Goya-Esteban, Antonio J Caamaño, José L Rojo-Álvarez, Carlos Martín-Caballero
Accurate identification of Perinatal Hypoxia from visual inspection of Fetal Heart Rate (FHR) has been shown to have limitations. An automated signal processing method for this purpose needs to deal with time series of different lengths, recording interruptions, and poor quality signal conditions. We propose a new method, robust to those issues, for automated detection of perinatal hypoxia by analyzing the FHR during labor. Our system consists of several stages: (a) time series segmentation; (b) feature extraction from FHR signals, including raw time series, moments, and usual heart rate variability indices; (c) similarity calculation with Normalized Compression Distance, which is the key element for dealing with FHR time series; and (d) a simple classification algorithm for providing the hypoxia detection...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28292850/clinical-outcomes-of-bronchiolitis-after-implementation-of-a-general-ward-high-flow-nasal-cannula-guideline
#10
Jeffrey Riese, Timothy Porter, Jamie Fierce, Alison Riese, Troy Richardson, Brian K Alverson
OBJECTIVE: The goal of this study was to assess the association of the introduction of a ward's high-flow nasal cannula (HFNC) guideline with clinical outcomes of infants with bronchiolitis. METHODS: We conducted a retrospective, pre-post intervention study with an interrupted time series analysis of infants admitted with bronchiolitis between 2010 and 2014 at an urban, tertiary care children's hospital. Patients admitted in the 24 months before and after initiation of a guideline for HFNC use on the general wards were compared...
March 14, 2017: Hospital Pediatrics
https://www.readbyqxmd.com/read/28291809/impact-of-a-structured-icu-training-programme-in-resource-limited-settings-in-asia
#11
Rashan Haniffa, Yoel Lubell, Ben S Cooper, Sanjib Mohanty, Shamsul Alam, Arjun Karki, Rajya Pattnaik, Ahmed Maswood, R Haque, Raju Pangeni, Marcus J Schultz, Arjen M Dondorp
OBJECTIVE: To assess the impact on ICU performance of a modular training program in three resource-limited general adult ICUs in India, Bangladesh, and Nepal. METHOD: A modular ICU training programme was evaluated using performance indicators from June 2009 to June 2012 using an interrupted time series design with an 8 to 15 month pre-intervention and 18 to 24 month post-intervention period. ICU physicians and nurses trained in Europe and the USA provided training for ICU doctors and nurses...
2017: PloS One
https://www.readbyqxmd.com/read/28283785/a-quality-improvement-initiative-to-reduce-central-line-infection-in-neonates-using-checklists
#12
Jacqueline E Taylor, Susan J McDonald, Arul Earnest, Jim Buttery, Bree Fusinato, Samantha Hovenden, Andrea Wallace, Kenneth Tan
Central line associated blood stream infections (CLABSI) are the most common complication of central catheters in neonates. These infections increase length of hospital stay, hospital costs and impact on mortality and morbidities. We performed a quasi-experimental study, over 24 months, utilising a pre-post design to determine the impact checklists had on central line infections. We introduced checklists for insertion, daily maintenance and procedural access based on the existing clinical guideline. Infections and compliance were monitored and reported back to the unit each month...
March 10, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28275705/distraction-in-diagnostic-radiology-how-is-search-through-volumetric-medical-images-affected-by-interruptions
#13
Lauren H Williams, Trafton Drew
Observational studies have shown that interruptions are a frequent occurrence in diagnostic radiology. The present study used an experimental design in order to quantify the cost of these interruptions during search through volumetric medical images. Participants searched through chest CT scans for nodules that are indicative of lung cancer. In half of the cases, search was interrupted by a series of true or false math equations. The primary cost of these interruptions was an increase in search time with no corresponding increase in accuracy or lung coverage...
2017: Cogn Res Princ Implic
https://www.readbyqxmd.com/read/28271236/the-impact-of-single-container-malt-liquor-sales-restrictions-on-urban-crime
#14
Patricia McKee, Darin J Erickson, Traci Toomey, Toben Nelson, Elyse Levine Less, Spruha Joshi, Rhonda Jones-Webb
Many US cities have adopted legal restrictions on high-alcohol malt liquor sales in response to reports of crime and nuisance behaviors around retail alcohol outlets. We assessed whether these policies are effective in reducing crime in urban areas. We used a rigorous interrupted time-series design with comparison groups to examine monthly crime rates in areas surrounding alcohol outlets in the 3 years before and after adoption of malt liquor sales restrictions in two US cities. Crime rates in matched comparison areas not subject to restrictions served as covariates...
March 7, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28265574/longitudinal-impact-of-the-smoking-ban-legislation-in-acute-coronary-syndrome-admissions
#15
D Abreu, P Sousa, C Matias-Dias, F J Pinto
Background and Purpose. The association between smoking and CV has been proved; however smoking is still the first preventable cause of death in the EU. We aim to evaluate the potential impact of the smoke ban on the number of ACS events in the Portuguese population. In addition, we evaluate the longitudinal effects of the smoking ban several years after its implementation. Methods. We analyzed the admission rate for ACS before and after the ban using data from hospital admission. Monthly crude rate was computed, using the Portuguese population as the denominator...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28259089/the-recovery-of-online-drug-markets-following-law-enforcement-and-other-disruptions
#16
Joe Van Buskirk, Raimondo Bruno, Timothy Dobbins, Courtney Breen, Lucinda Burns, Sundresan Naicker, Amanda Roxburgh
INTRODUCTION: Online drug markets operating on the 'darknet' ('cryptomarkets') facilitate the trade of illicit substances at an international level. The present study assessed the longitudinal impact on cryptomarket trading of two major disruptions: a large international law enforcement operation, 'Operation Onymous'; and the closure of the largest cryptomarket, Evolution. METHODS: Almost 1150 weekly snapshots of a total of 39 cryptomarkets were collected between October 2013 and November 2015...
February 20, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28255995/meaningful-use-and-hospital-performance-on-post-acute-utilization-indicators
#17
Yanick N Brice, Karen E Joynt, Christopher P Tompkins, Grant A Ritter
OBJECTIVES: To examine trends in hospital post-acute utilization indicators and to determine whether improvement in these indicators is associated with attesting to meaningful use (MU). DATA SOURCES: Medicare claims-based, repeated measures on 30-day hospital-wide all-cause readmission and emergency department (ED) utilization rates for 160 short-stay hospitals (2009-2012); Medicare EHR Incentive Program Payments files (2011-2012); and other hospital and market data...
March 2, 2017: Health Services Research
https://www.readbyqxmd.com/read/28253914/non-pharmacological-interventions-designed-to-reduce-health-risks-due-to-unhealthy-eating-behaviour-and-linked-risky-or-excessive-drinking-in-adults-aged-18-25%C3%A2-years-a-systematic-review-protocol
#18
Stephanie Scott, Kathryn Parkinson, Eileen Kaner, Shannon Robalino, Martine Stead, Christine Power, Niamh Fitzgerald, Wendy Wrieden, Ashley Adamson
BACKGROUND: Excess body weight and heavy alcohol consumption are two of the greatest contributors to global disease. Alcohol use peaks in early adulthood. Alcohol consumption can also exacerbate weight gain. A high body mass index and heavy drinking are independently associated with liver disease but, in combination, they produce an intensified risk of damage, with individuals from lower socio-economic status groups disproportionately affected. METHODS: We will conduct searches in MEDLINE, Embase, PubMed, PsycINFO, ERIC, ASSIA, Web of Knowledge (WoK), Scopus, CINAHL via EBSCO, LILACS, CENTRAL and ProQuest Dissertations and Theses for studies that assess targeted preventative interventions of any length of time or duration of follow-up that are focused on reducing unhealthy eating behaviour and linked risky alcohol use in 18-25-year-olds...
March 3, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28253540/payment-methods-for-outpatient-care-facilities
#19
REVIEW
Beibei Yuan, Li He, Qingyue Meng, Liying Jia
BACKGROUND: Outpatient care facilities provide a variety of basic healthcare services to individuals who do not require hospitalisation or institutionalisation, and are usually the patient's first contact. The provision of outpatient care contributes to immediate and large gains in health status, and a large portion of total health expenditure goes to outpatient healthcare services. Payment method is one of the most important incentive methods applied by purchasers to guide the performance of outpatient care providers...
March 3, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28249067/adoption-of-the-2013-american-college-of-cardiology-american-heart-association-cholesterol-management-guideline-in-cardiology-practices-nationwide
#20
Yashashwi Pokharel, Fengming Tang, Philip G Jones, Vijay Nambi, Vera A Bittner, Ravi S Hira, Khurram Nasir, Paul S Chan, Thomas M Maddox, William J Oetgen, Paul A Heidenreich, William B Borden, John A Spertus, Laura A Petersen, Christie M Ballantyne, Salim S Virani
Importance: The 2013 American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Management Guideline recommends moderate-intensity to high-intensity statin therapy in eligible patients. Objective: To examine adoption of the 2013 ACC/AHA guideline in US cardiology practices. Design, Setting, and Participants: Among 161 cardiology practices, trends in the use of moderate-intensity to high-intensity statin and nonstatin lipid-lowering therapy (LLT) were analyzed before (September 1, 2012, to November 1, 2013) and after (February 1, 2014, to April 1, 2015) publication of the 2013 ACC/AHA guideline among 4 mutually exclusive risk groups within the ACC Practice Innovation and Clinical Excellence Registry...
March 1, 2017: JAMA Cardiology
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