Yujin Ding, Pan Zhang, Tuo Deng, Xiang Yan, Min Zhang, Zhiguo Xie, Gan Huang, Ping Wang, Ting Cai, Xiaoli Zhang, Xinqiang Xiao, Ying Xia, Bingwen Liu, Ya Peng, Xiaohan Tang, Min Hu, Yang Xiao, Xia Li, Erik De Clercq, Guangdi Li, Zhiguang Zhou
AIMS: This study aims to investigate the interplay between hepatitis C virus (HCV) infection and major forms of diabetes: type 1 diabetes (T1D), type 2 diabetes (T2D), and latent autoimmune diabetes in adults (LADA). METHODS: This multicenter study analyzed a cohort of 2699 diabetic and 7344 non-diabetic subjects who visited medical centers in China from 2014 to 2021. T1D, T2D, LADA, and HCV were diagnosed using standard procedures. High-throughput sequencing was conducted to identify genetic footprints of human leukocyte antigen (HLA) alleles and haplotypes at the DRB1, DQA1, and DQB1 loci...
December 29, 2023: Diabetes & Metabolic Syndrome