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DES Exposure

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https://www.readbyqxmd.com/read/29443486/effects-on-patients-of-variations-in-the-implementation-of-a-cardiometabolic-risk-intervention-program-in-montr%C3%A3-al
#1
Marie-Ève Beauregard, Sylvie Provost, Raynald Pineault, Dominique Grimard, José Pérez, Michel Fournier
INTRODUCTION: In 2011, the Agence de la santé et des services sociaux de Montréal (ASSSM), in partnership with the region's Centres de santé et de services sociaux (CSSS), coordinated the implementation of a program on cardiometabolic risk based on the Chronic Care Model. The program, intended for patients suffering from diabetes or hypertension, involved a series of individual follow-up appointments, group classes and exercise sessions. Our study assesses the impact on patient health outcomes of variations in the implementation of some aspects of the program among the six CSSSs taking part in the study...
February 2018: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29409055/effectiveness-of-additional-lead-shielding-to-protect-staff-from-scattering-radiation-during-endoscopic-retrograde-cholangiopancreatography-procedures
#2
Yoshiaki Morishima, Koichi Chida, Takayoshi Meguro
Endoscopic retrograde cholangiopancreatography (ERCP) is often complex and involves long fluoroscopic times, with significant radiation exposure to medical staff. We investigated protective effects of an additional attached lead shielding device. The lead shielding device covered with the X-ray tube table (0.125 mm lead equivalent) during ERCP procedures. Fluoroscopy scatter radiation, with or without the lead shielding device, was measured using an acrylic phantom and a radiation survey meter. Measurements (25 points) were made at 50 cm intervals, at both 90 and 150 cm above the floor...
February 2, 2018: Journal of Radiation Research
https://www.readbyqxmd.com/read/29407680/factors-associated-with-successful-vs-unsuccessful-smoking-cessation-data-from-a-nationally-representative-study
#3
Fabienne El-Khoury Lesueur, Camille Bolze, Maria Melchior
INTRODUCTION: A substantial proportion of smokers who attempt to stop smoking relapse in the first months. Yet to date, there is limited understanding of the predictors of smoking attempts and their success. We examine the role of tobacco use characteristics, other substance-related factors, as well as socio-demographic characteristics in relation to successful and unsuccessful smoking cessation. METHODS: DePICT (Description des Perceptions, Images, et Comportements liés au Tabagisme) is a nationally representative sample of adults aged between 18 and 64years residing in metropolitan France, who were interviewed by telephone survey (n=4342)...
February 1, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29397003/outcome-of-full-pulpotomy-using-biodentine-in-adult-patients-with-symptoms-indicative-of-irreversible-pulpitis
#4
N A Taha, S Z Abdelkhader
AIM: To assess the outcome of full pulpotomy using Biodentine in permanent teeth with carious exposures and symptoms indicative of irreversible pulpitis. METHODOLOGY: Sixty-four permanent molar teeth with symptomatic vital pulps in 52 patients aged 19-69 years were included. Preoperative pulpal and periapical diagnosis was established. After informed consent the tooth was anaesthetized, isolated using rubber dam and disinfected with 5% NaOCl before caries excavation; subsequently the pulp was amputated to the level of the canal orifices...
February 3, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29340879/diethylstilbestrol-arrested-spermatogenesis-and-somatic-growth-in-the-juveniles-of-yellow-catfish-pelteobagrus-fulvidraco-a-fish-with-sexual-dimorphic-growth
#5
Zhi-Hao Liu, Qi-Liang Chen, Qiang Chen, Fang Li, Ying-Wen Li
In fish, spermatogenesis and somatic growth are mainly regulated by hypothalamic-pituitary-gonadal (HPG) and hypothalamic-pituitary-somatic (HPS) axes, respectively. Xenoestrogens have been reported to impair spermatogenesis in some fishes, and arrest somatic growth in some others, whereas, whether xenoestrogens are capable of disrupting spermatogenesis and somatic growth simultaneously in fish that exhibits sexual dimorphic growth is little known, and the underlying mechanisms remain poorly understood. In this study, male juveniles of yellow catfish (Pelteobagrus fulvidraco), which exhibits a sexual dimorphic growth that favors males, were exposed to diethylstilbestrol (DES) for 28 days...
January 16, 2018: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29326091/erratum-regulation-of-chromatin-assembly-and-cell-transformation-by-formaldehyde-exposure-in-human-cells
#6
Danqi Chen, Lei Fang, Shenglin Mei, Hongjie Li, Xia Xu, Thomas L Des Marais, Kun Lu, X Shirley Liu, Chunyuan Jin
[This corrects the article DOI: 10.1289/EHP1275.].
January 3, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29294725/association-of-domestic-violence-against-women-with-sociodemographic-factors-clinical-features-and-dissociative-symptoms-in-patients-who-receive-services-from-psychiatric-outpatient-units-in-turkey
#7
Zeynep Kotan, Vahap Ozan Kotan, Hayriye Dilek Yalvaç, Sibel Demir
Domestic violence (DV) against women is a serious problem with its negative effects on all family members and the society. Women exposed to DV not only have physical but also psychological damage. This study investigates prevalence of DV and its relations with some descriptive and clinical features in a psychiatric outpatient population in Turkey. A total of 277 female outpatients were included in the study. After a semistructured clinical interview, they were assessed by sociodemographic data form, DV questionnaire, Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Rating Scale (HARS), Dissociative Experiences Scale (DES), and Somatoform Dissociation Questionnaire (SDQ)...
April 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29275294/effects-of-2-3-bis-4-hydroxyphenyl-propionitrile-on-induction-of-polyovular-follicles-in-the-mouse-ovary
#8
Tomomi Sato, Hannah Kim, Hanako Kakuta, Taisen Iguchi
BACKGROUND/AIM: Neonatal diethylstilbestrol (DES) treatment induces polyovular follicles (PFs), which contain more than two oocytes in a follicle, through estrogen receptor (ER) β, not ERα. 2,3-Bis(4-hydroxyphenyl)-propionitrile (DPN) is a specific ERβ agonist; the effects of neonatal DPN exposure on PF induction and gene expression in the mouse ovary were examined. MATERIALS AND METHODS: Histological analysis and real-time reverse transcription-polymerase chain reaction were performed...
January 2018: In Vivo
https://www.readbyqxmd.com/read/29219636/physiological-effects-of-brominated-flame-retardants-on-nc-nga-mice
#9
Michitaka Tanaka, Ken-Ichiro Inoue, Akinori Shimada, Hirohisa Takano
PURPOSE: Brominated flame retardants (BFRs) are used as an additive or reactive components in various materials. Regarding their health concerns, their immunotoxicity have not been clarified yet. MATERIALS AND METHODS: In the current study, we examined the effects of systemic exposure to two types of BFRs, DE71 and DE79, on pathophysiologic traits of murine atopic dermatitis (AD). Male NC/Nga mice were repeatedly injected intraperitoneally with DE71 and DE79 and/or mite allergen (Dermatophagoides pteronyssinus: Dp) into their right ears...
December 8, 2017: Immunopharmacology and Immunotoxicology
https://www.readbyqxmd.com/read/29216539/influence-of-extracellular-environment-on-the-motility-and-structural-properties-of-spermatozoa-collected-from-hormonally-stimulated-panamanian-golden-frog-atelopus-zeteki
#10
Gina Della Togna, Brian Gratwicke, Matthew Evans, Lauren Augustine, Han Chia, Ed Bronikowski, James B Murphy, Pierre Comizzoli
A better understanding of the factors influencing the biology of amphibian spermatozoa after release from the testis is a prerequisite to the development of sperm preservation methods. The objective of the study was to determine the effect of extracellular conditions (exposure to water and different temperatures) over time on the sperm motility and structural properties (including morphology and DNA integrity) collected from hormonally stimulated Atelopus zeteki. Following intraperitoneal injection of gonadotropin-releasing hormone agonist (des-Gly10, D-Ala6, Pro-NHEt9 GnRH; 4 μg/g of body weight), human chorionic gonadotropin (hCG, 10 IU/gbw), or Amphiplex™ (0...
November 29, 2017: Theriogenology
https://www.readbyqxmd.com/read/29146150/the-effect-of-cold-acclimation-on-active-ion-transport-in-cricket-ionoregulatory-tissues
#11
Lauren E Des Marteaux, Soheila Khazraeenia, Gil Y Yerushalmi, Andrew Donini, Natalia G Li, Brent J Sinclair
Cold-acclimated insects defend ion and water transport function during cold exposure. We hypothesized that this is achieved via enhanced active transport. The Malpighian tubules and rectum are likely targets for such transport modifications, and recent transcriptomic studies indicate shifts in Na(+)-K(+) ATPase (NKA) and V-ATPase expression in these tissues following cold acclimation. Here we quantify the effect of cold acclimation (one week at 12°C) on active transport in the ionoregulatory organs of adult Gryllus pennsylvanicus field crickets...
November 13, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/29124779/prenatal-diethylstilbestrol-exposure-and-cancer-risk-in-women
#12
Rebecca Troisi, Elizabeth E Hatch, Linda Titus, William Strohsnitter, Mitchell H Gail, Dezheng Huo, Ervin Adam, Stanley J Robboy, Marianne Hyer, Robert N Hoover, Julie R Palmer
In the Diethylstilbestrol [DES] Combined Cohort Follow-up, the age- and calendar-year specific standardized incidence ratio [SIR] for clear cell adenocarcinoma [CCA] was 27.6 (95% confidence interval [CI] 7.51-70.6) for the exposed women. The SIR for breast cancer was 1.17 (95% CI 1.01-1.36) and the hazard ratio [HR] adjusted for birth year and cohort for comparison with the unexposed was 1.05 (95% CI 0.79-1.41). The SIR for pancreatic cancer was 2.43 (95% CI 1.21-4.34) and the adjusted HR for comparison with unexposed women was 7...
November 10, 2017: Environmental and Molecular Mutagenesis
https://www.readbyqxmd.com/read/29081918/seroprevalence-and-risk-factors-for-peste-des-petits-ruminants-and-selected-differential-diagnosis-in-sheep-and-goats-in-tanzania
#13
Emeli Torsson, Mikael Berg, Gerald Misinzo, Ida Herbe, Tebogo Kgotlele, Malin Päärni, Nils Roos, Anne-Lie Blomström, Karl Ståhl, Jonas Johansson Wensman
Introduction: Livestock husbandry is critical for food security and poverty reduction in a low-income country like Tanzania. Infectious disease is one of the major constraints reducing the productivity in this sector. Peste des petits ruminants (PPR) is one of the most important diseases affecting small ruminants, but other infectious diseases may also be present. Objective: The objective of this study was to determine the seroprevalence and risk factors for exposure to PPR, contagious caprine pleuropneumonia (CCPP), foot-and-mouth disease (FMD), bluetongue (BT), and bovine viral diarrhoea (BVD) in sheep and goats in Tanzania...
2017: Infection Ecology & Epidemiology
https://www.readbyqxmd.com/read/29069384/a-prospective-cohort-study-of-prenatal-diethylstilbestrol-exposure-and-cardiovascular-disease-risk
#14
Rebecca Troisi, Linda Titus, Elizabeth E Hatch, Julie R Palmer, Dezheng Huo, William C Strohsnitter, Ervin Adam, Winnie Ricker, Marianne Hyer, Robert N Hoover
Purpose: Prenatal exposure to diethylstilbestrol (DES), a prototype endocrine disrupting chemical, is associated with risk of adverse reproductive outcomes and cancer in women. We investigated whether cardiovascular disease (CVD) risk might also be greater in prenatally DES exposed women. Methods: DES exposed (n=3941) and unexposed (n=1705) women participating in the Diethylstilbestrol Combined Cohort Follow-up Study were followed prospectively from 1994-2013. Prenatal DES exposure (or lack of exposure) was documented in the birth record or physician's note...
October 20, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29066032/-night-workers-exposure-to-harshness-factors-in-france-lessons-learned-from-the-2010%C3%A2-sumer-survey
#15
N Havet, M Huguet, J Tonietta
BACKGROUND: Despite the fact that French laws state that night work should be exceptional, the number of night workers has sharply increased in the past 20 years. At the same time, empirical and epidemiological studies indicate that night work has negative effects on workers' health. This is why the 2010 French pension act considered night work to be a drudgery. The aim of this study is to investigate whether night workers are more subject to other factors defined as contributing to the drudgery of work than are day workers...
November 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/29051608/transcription-factors-and-stress-response-gene-alterations-in-human-keratinocytes-following-solar-simulated-ultra-violet-radiation
#16
Thomas L Des Marais, Thomas Kluz, Dazhong Xu, Xiaoru Zhang, Lisa Gesumaria, Mary S Matsui, Max Costa, Hong Sun
Ultraviolet radiation (UVR) from sunlight is the major effector for skin aging and carcinogenesis. However, genes and pathways altered by solar-simulated UVR (ssUVR), a mixture of UVA and UVB, are not well characterized. Here we report global changes in gene expression as well as associated pathways and upstream transcription factors in human keratinocytes exposed to ssUVR. Human HaCaT keratinocytes were exposed to either a single dose or 5 repetitive doses of ssUVR. Comprehensive analyses of gene expression profiles as well as functional annotation were performed at 24 hours post irradiation...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29028249/a-method-to-quantitatively-assess-dermal-exposure-to-volatile-organic-compounds
#17
Matteo Creta, Katrien Poels, Laurens Thoelen, Karine Vranckx, Peter Collaerts, Fleur Jansen, Michel Vangeel, Lode Godderis, Radu-Corneliu Duca, Jeroen A J Vanoirbeek
Assessing dermal exposure of workers to noxious chemicals becomes increasingly important in industrial settings. Among various chemicals, volatile organic compounds (VOCs) are widely used in industrialized countries, but still there are no validated methodologies able to accurately quantify skin exposure. In this study, we developed a sensitive methodology based on activated charcoal cloth (ACC) to quantitatively assess skin exposure to 181 VOCs. The majority of the VOCs (156) showed a constant desorption efficiency (DE) of ~100% over the studied concentration range...
October 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/28990450/revisiting-the-role-of-durable-polymers-in-cardiovascular-devices
#18
Hiroyoshi Mori, Fumiyuki Otsuka, Anuj Gupta, Hiroyuki Jinnouchi, Sho Torii, Emanuel Harari, Renu Virmani, Aloke V Finn
Polymers are an essential component of drug-eluting stents (DES) used to control drug release but remain the most controversial component of DES technology. There are two types of polymers employed in DES: durable polymer based DES (DP-DES) and biodegradable polymer DES (BP-DES). First-generation DES were exclusively composed of DP and demonstrated increased rates of late stent failure due in part to poor polymer biocompatibility. Newer generations DES use more biocompatible durable polymers or biodegradable polymers...
November 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28960386/diethylstilbestrol-impaired-oogenesis-of-yellow-catfish-juveniles-through-disrupting-hypothalamic-pituitary-gonadal-axis-and-germ-cell-development
#19
Yaqin Wang, Yingwen Li, Qiliang Chen, Zhihao Liu
Diethylstilbestrol (DES), a non-steroidal estrogen, has been found to cause altered germ cell development and disordered ovarian development in fish females. However, the mechanisms that might be involved are poorly understood. In this study, female juveniles of yellow catfish (Pelteobagrus fulvidraco) (120 days post-hatching) were exposed to two doses (10 and 100 ng l(-1) ) of DES for 28 days. After the endpoint of exposure, decreased ovary weight and gonadosomatic index, as well as various ovarian impairments were observed in response to DES...
September 28, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28945747/establishment-of-primary-mixed-cell-cultures-from-spontaneous-canine-mammary-tumors-characterization-of-classic-and-new-cancer-associated-molecules
#20
Luciana B Gentile, Marcia K Nagamine, Luiz R Biondi, Daniel S Sanches, Fábio Toyota, Tatiane M Giovani, Isis P de Jesus, Ivone I M da Fonseca, Nicolle Queiroz-Hazarbassanov, Bruno L Diaz, Cristina de O Massoco Salles Gomes, Maria Lucia Z Dagli
There are many factors which make canine cancer like cancer in humans. The occurrence of spontaneous mammary tumors in pet dogs, tumor genetics, molecular targets and exposure to the same environmental risk factors are among these factors. Therefore, the study of canine cancer can provide useful information to the oncology field. This study aimed to establish and characterize a panel of primary mixed cell cultures obtained from spontaneous canine mammary tumors. Eight established cell cultures obtained from one normal mammary gland, one complex adenoma, one mixed adenoma, two complex carcinomas and two mixed carcinomas were analyzed...
2017: PloS One
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